MCID: TTH002
MIFTS: 62

Tooth Agenesis

Categories: Genetic diseases, Oral diseases, Rare diseases

Aliases & Classifications for Tooth Agenesis

MalaCards integrated aliases for Tooth Agenesis:

Name: Tooth Agenesis 12 37 6 15 17
Oligodontia 12 59 29 6
Selective Tooth Agenesis 12 59 6
Hypodontia 12 55 40
Tooth Agenesis, Selective 55
Familial Tooth Agenesis 12
Anodontia 44

Characteristics:

Orphanet epidemiological data:

59
oligodontia
Inheritance: Autosomal dominant,Autosomal recessive,X-linked recessive; Age of onset: Childhood; Age of death: normal life expectancy;

Classifications:

Orphanet: 59  
Rare odontological diseases


External Ids:

Disease Ontology 12 DOID:0050591
KEGG 37 H00625
ICD9CM 35 520.0
MeSH 44 D000848
SNOMED-CT 68 16958000 26624006
ICD10 33 K00.0
ICD10 via Orphanet 34 K00.0
Orphanet 59 ORPHA99798
UMLS 72 C0399352

Summaries for Tooth Agenesis

KEGG : 37
Tooth agenesis, or hypodontia/origodontia, refers to the congenital absence of a few teeth without any systemic disorders. Tooth development is a complex process that involves interactions between the oral epithelium and an underlying mesenchyme. Perturbation of this process results in tooth agenesis. This disease could be inherited as either an autosomal dominant, autosomal recessive, or X-linked trait.

MalaCards based summary : Tooth Agenesis, also known as oligodontia, is related to ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant and ectodermal dysplasia. An important gene associated with Tooth Agenesis is PAX9 (Paired Box 9), and among its related pathways/superpathways are Wnt signaling pathway and Nanog in Mammalian ESC Pluripotency. The drugs Amoxicillin and Ibuprofen have been mentioned in the context of this disorder. Affiliated tissues include bone, eye and salivary gland, and related phenotypes are micrognathia and microdontia

Disease Ontology : 12 A tooth disease characterized by failure to develop on or more missing teeth.

Wikipedia : 75 Hypodontia is defined as the developmental absence of one or more teeth (excluding the third molars)... more...

Related Diseases for Tooth Agenesis

Diseases related to Tooth Agenesis via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 341, show less)
# Related Disease Score Top Affiliating Genes
1 ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant 32.5 EDARADD EDAR
2 ectodermal dysplasia 31.7 WNT10A EDARADD EDAR EDA DSP
3 ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive 31.4 WNT10A PAX9 MSX1 EDARADD EDAR EDA
4 cleft lip/palate 31.3 TGFA MSX1 IRF6 FGFR1 CDH1 BMP4
5 anodontia 31.2 PAX9 MSX1 EDARADD EDA AXIN2
6 cleft palate, isolated 31.1 TGFB3 TGFA PAX9 MSX1 IRF6 FGFR1
7 cleft lip and alveolus 31.0 MSX1 IRF6
8 tooth size 31.0 PAX9 MSX1 BMP4
9 hypohidrotic ectodermal dysplasia autosomal recessive 31.0 WNT10A EDARADD EDAR
10 cleft lip 30.7 TGFB3 TGFA SUMO1 PAX9 MSX1 IRF6
11 orofacial cleft 30.7 SUMO1 MSX1 IRF6 BMP4
12 split hand-foot malformation 30.5 WNT10B SUMO1 FGFR1
13 tooth agenesis, selective, 1 12.8
14 tooth agenesis, selective, 4 12.8
15 tooth agenesis, selective, 3 12.7
16 tooth agenesis, selective, x-linked, 1 12.7
17 tooth agenesis, selective, 7 12.6
18 tooth agenesis, selective, 8 12.6
19 tooth agenesis, selective, 9 12.6
20 cardiomyopathy, dilated, with woolly hair, keratoderma, and tooth agenesis 12.6
21 leukodystrophy, hypomyelinating, 8, with or without oligodontia and/or hypogonadotropic hypogonadism 12.6
22 malposition of teeth with or without hypodontia/oligodontia 12.5
23 tooth agenesis, selective, 5 12.4
24 hypodontia, x-linked 12.4
25 microdontia hypodontia short stature 12.4
26 leukomelanoderma, infantilism, mental retardation, hypodontia, hypotrichosis 12.3
27 brachymetapody-anodontia-hypotrichosis-albinoidism 12.3
28 tooth agenesis, selective, 2 12.3
29 facial dysmorphism, selective tooth agenesis, and choroid calcification 12.2
30 witkop syndrome 12.2
31 epidermolysis bullosa simplex with anodontia/hypodontia 12.2
32 cleft palate, deafness, and oligodontia 12.2
33 split-hand and split-foot with hypodontia 12.2
34 congenital heart disease ptosis hypodontia craniostosis 12.2
35 cleft lip palate oligodontia syndactyly pili torti 12.2
36 cleft palate stapes fixation oligodontia 12.2
37 polr3-related leukodystrophy 12.1
38 leukodystrophy, hypomyelinating, 7, with or without oligodontia and/or hypogonadotropic hypogonadism 12.1
39 oligodontia-colorectal cancer syndrome 12.1
40 adult syndrome 12.0
41 dermatoosteolysis, kirghizian type 11.9
42 deafness-oligodontia syndrome 11.9
43 zadik barak levin syndrome 11.9
44 dental anomalies and short stature 11.6
45 late-onset localized junctional epidermolysis bullosa-intellectual disability syndrome 11.5
46 ectodermal dysplasia 13, hair/tooth type 11.5
47 martinez monasterio pinheiro syndrome 11.5
48 mehta lewis patton syndrome 11.4
49 dentin dysplasia, type i 11.4
50 rapp-hodgkin syndrome 11.4
51 limb-mammary syndrome 11.4
52 ankyloblepharon-ectodermal defects-cleft lip/palate 11.3
53 ectodermal dysplasia, trichoodontoonychial type 11.3
54 anauxetic dysplasia 1 11.3
55 blepharocheilodontic syndrome 1 11.2
56 deafness, congenital, with onychodystrophy, autosomal dominant 11.2
57 ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome 11.2
58 blepharocheilodontic syndrome 2 11.2
59 osteoglophonic dysplasia 11.2
60 cranioectodermal dysplasia 1 11.2
61 even-plus syndrome 11.2
62 anauxetic dysplasia 2 11.2
63 ectodermal dysplasia 14, hair/tooth type with or without hypohidrosis 11.2
64 trichorhinophalangeal syndrome, type ii 11.1
65 schimmelpenning-feuerstein-mims syndrome 11.1
66 trichorhinophalangeal syndrome, type i 11.1
67 johanson-blizzard syndrome 11.1
68 lipoid proteinosis of urbach and wiethe 11.1
69 ectodermal dysplasia with natal teeth, turnpenny type 11.1
70 acrofacial dysostosis, palagonia type 11.1
71 zechi-ceide syndrome 11.1
72 acrofacial dysostosis, patagonia type 11.1
73 autosomal dominant deafness-onychodystrophy syndrome 11.1
74 bork stender schmidt syndrome 11.1
75 stoll alembik finck syndrome 11.1
76 angel-shaped phalangoepiphyseal dysplasia 11.0
77 lacrimoauriculodentodigital syndrome 11.0
78 axenfeld-rieger syndrome, type 1 11.0
79 weyers acrofacial dysostosis 11.0
80 amelogenesis imperfecta, type ig 11.0
81 cerebellar ataxia and ectodermal dysplasia 11.0
82 faciocardiorenal syndrome 11.0
83 pilodental dysplasia with refractive errors 11.0
84 wiedemann-rautenstrauch syndrome 11.0
85 short syndrome 11.0
86 ectodermal dysplasia and immunodeficiency 1 11.0
87 arthrogryposis, ectodermal dysplasia, cleft lip/palate, and developmental delay 11.0
88 ectodermal dysplasia 1, hypohidrotic, x-linked 11.0
89 nicolaides-baraitser syndrome 11.0
90 ichthyosis, leukocyte vacuoles, alopecia, and sclerosing cholangitis 11.0
91 lelis syndrome 11.0
92 alopecia, neurologic defects, and endocrinopathy syndrome 11.0
93 fontaine progeroid syndrome 11.0
94 ectodermal dysplasia 11a, hypohidrotic/hair/tooth type, autosomal dominant 11.0
95 ectodermal dysplasia 11b, hypohidrotic/hair/tooth type, autosomal recessive 11.0
96 epileptic encephalopathy, early infantile, 25, with amelogenesis imperfecta 11.0
97 ectodermal dysplasia 12, hypohidrotic/hair/tooth/nail type 11.0
98 charlie m syndrome 11.0
99 odonto onycho dysplasia with alopecia 11.0
100 pinheiro freire-maia miranda syndrome 11.0
101 zlotogora syndrome 11.0
102 syngnathia 10.8 MSX1 IRF6 BMP4
103 familial isolated arrhythmogenic ventricular dysplasia, left dominant form 10.7 TGFB3 DSP
104 familial isolated arrhythmogenic ventricular dysplasia, biventricular form 10.7 TGFB3 DSP
105 clouston syndrome 10.7 WNT10A EDARADD EDAR EDA
106 familial isolated arrhythmogenic ventricular dysplasia, right dominant form 10.7 TGFB3 DSP
107 isolated cleft lip 10.7 MSX1 IRF6
108 physical disorder 10.7 TGFB3 MSX1 IRF6 BMP4
109 synovial chondromatosis 10.7 TGFB3 FGFR1 BMP4
110 cocoon syndrome 10.6 TGFB3 IRF6
111 fibular aplasia or hypoplasia, femoral bowing and poly-, syn-, and oligodactyly 10.6 WNT10A PAX9 MSX1 GREM2 EDARADD EDAR
112 arrhythmogenic right ventricular dysplasia, familial, 1 10.5 TGFB3 DSP
113 arrhythmogenic right ventricular dysplasia, familial, 9 10.4 TGFB3 DSP
114 hypotrichosis 10.4
115 hypogonadotropic hypogonadism 10.3
116 anhidrosis 10.3
117 hypogonadism 10.3
118 hypogonadotropism 10.3
119 ataxia and polyneuropathy, adult-onset 10.3
120 gapo syndrome 10.3
121 arrhythmogenic right ventricular dysplasia, familial, 8 10.3 TGFB3 DSP
122 hair whorl 10.2
123 down syndrome 10.2
124 orofacial clefting syndrome 10.2
125 split-hand/foot malformation 1 10.2
126 leukodystrophy 10.2
127 keratosis 10.2
128 hidrotic ectodermal dysplasia 2 10.2
129 taurodontism 10.2
130 nail disorder, nonsyndromic congenital, 9 10.1
131 ankylosis 10.1
132 craniosynostosis 10.1
133 isolated split hand-split foot malformation 10.1
134 colorectal cancer 10.1
135 odontoonychodermal dysplasia 10.1
136 isolated pierre robin sequence 10.1
137 cherubism 10.1
138 treacher collins syndrome 1 10.1
139 wolf-hirschhorn syndrome 10.1
140 chromosome 4p deletion 10.1
141 regional odontodysplasia 10.1
142 ankyloglossia with or without tooth anomalies 10.0
143 sotos syndrome 1 10.0
144 ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 1 10.0
145 hemifacial microsomia 10.0
146 strabismus 10.0
147 chromosome 2q35 duplication syndrome 10.0
148 aceruloplasminemia 10.0
149 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.0
150 autosomal recessive disease 10.0
151 dental caries 10.0
152 learning disability 10.0
153 mechanical strabismus 10.0
154 epidermolysis bullosa, late-onset localized junctional, with mental retardation 10.0
155 nephronophthisis 1 10.0
156 rothmund-thomson syndrome 10.0
157 erythrokeratodermia variabilis et progressiva 5 10.0
158 patau syndrome 10.0
159 diarrhea 10.0
160 epidermolysis bullosa simplex 10.0
161 waardenburg's syndrome 10.0
162 periodontosis 10.0
163 medullary sponge kidney 10.0
164 van der woude syndrome 1 10.0
165 teeth, supernumerary 10.0
166 incontinentia pigmenti 10.0
167 brittle bone disorder 10.0
168 root resorption 10.0
169 dentinogenesis imperfecta 10.0
170 col1a1/2-related osteogenesis imperfecta 10.0
171 cleft lip with or without cleft palate 10.0
172 achondroplasia 9.9
173 chorea, benign hereditary 9.9
174 floating-harbor syndrome 9.9
175 hypercholesterolemia, familial, 1 9.9
176 hypertelorism 9.9
177 keratitis, hereditary 9.9
178 macroglossia 9.9
179 microcephaly, autosomal dominant 9.9
180 otitis media 9.9
181 steatocystoma multiplex 9.9
182 anodontia of permanent dentition 9.9
183 ellis-van creveld syndrome 9.9
184 hyaline fibromatosis syndrome 9.9
185 metachromatic leukodystrophy 9.9
186 microcephaly 1, primary, autosomal recessive 9.9
187 pseudoxanthoma elasticum 9.9
188 tibial hemimelia 9.9
189 focal dermal hypoplasia 9.9
190 orthostatic intolerance 9.9
191 chorea, childhood-onset, with psychomotor retardation 9.9
192 nevus comedonicus 9.9
193 seckel syndrome 9.9
194 mucositis 9.9
195 suppression amblyopia 9.9
196 amblyopia 9.9
197 interstitial nephritis 9.9
198 juvenile glaucoma 9.9
199 polycystic ovary syndrome 9.9
200 choreatic disease 9.9
201 dilated cardiomyopathy 9.9
202 osteopetrosis 9.9
203 polyneuropathy 9.9
204 thrombocytopenia 9.9
205 hyperostosis 9.9
206 syringoma 9.9
207 focal epilepsy 9.9
208 corneal dystrophy 9.9
209 dermatitis 9.9
210 syphilis 9.9
211 pustulosis of palm and sole 9.9
212 mitral valve disease 9.9
213 psoriasis 9.9
214 hard palate cancer 9.9
215 congenital syphilis 9.9
216 geleophysic dysplasia 9.9
217 nkx2-1-related disorders 9.9
218 48,xyyy 9.9
219 chromosome 9q duplication 9.9
220 dwarfism 9.9
221 pachygyria 9.9
222 woolly hair syndrome 9.9
223 hemimelia 9.9
224 temporomandibular joint anomaly 9.9
225 acanthosis nigricans 9.9
226 aniridia 1 9.9
227 book syndrome 9.9
228 alagille syndrome 1 9.9
229 coloboma of macula 9.9
230 dupuytren contracture 9.9
231 ear malformation 9.9
232 spondyloepiphyseal dysplasia with congenital joint dislocations 9.9
233 hypotrichosis 4 9.9
234 ige responsiveness, atopic 9.9
235 actinic prurigo 9.9
236 smith-magenis syndrome 9.9
237 teeth present at birth 9.9
238 telecanthus 9.9
239 uvula, bifid 9.9
240 wolff-parkinson-white syndrome 9.9
241 yunis-varon syndrome 9.9
242 fraser syndrome 1 9.9
243 cryptorchidism, unilateral or bilateral 9.9
244 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 9.9
245 papillon-lefevre syndrome 9.9
246 neu-laxova syndrome 1 9.9
247 teeth, congenital absence of, with taurodontia and sparse hair 9.9
248 teeth, fused 9.9
249 yemenite deaf-blind hypopigmentation syndrome 9.9
250 langerhans cell histiocytosis 9.9
251 split-hand/foot malformation 4 9.9
252 hurler syndrome 9.9
253 choanal atresia, posterior 9.9
254 leukodystrophy, hypomyelinating, 5 9.9
255 intraocular pressure quantitative trait locus 9.9
256 glass syndrome 9.9
257 alacrima, achalasia, and mental retardation syndrome 9.9
258 leukoencephalopathy with ataxia 9.9
259 fibroma 9.9
260 scoliosis 9.9
261 ptosis 9.9
262 hypomyelinating leukodystrophy 9.9
263 sensorineural hearing loss 9.9
264 fanconi syndrome 9.9
265 chronic apical periodontitis 9.9
266 heart disease 9.9
267 synostosis 9.9
268 lacrimal duct obstruction 9.9
269 dysostosis 9.9
270 gingivitis 9.9
271 palmoplantar keratosis 9.9
272 histiocytosis 9.9
273 epidermolysis bullosa dystrophica 9.9
274 peripheral nervous system disease 9.9
275 situs inversus 9.9
276 periapical periodontitis 9.9
277 cataract 9.9
278 neuropathy 9.9
279 exophthalmos 9.9
280 microcephaly 9.9
281 clcn2-related leukoencephalopathy 9.9
282 fgfr-related craniosynostosis syndromes 9.9
283 pnpla6-related disorders 9.9
284 satb2-associated syndrome 9.9
285 sickle cell disease 9.9
286 tp63-related disorders 9.9
287 47, xxy 9.9
288 cleft palate x-linked 9.9
289 cryptophthalmos 9.9
290 erythrokeratoderma ''en cocardes'' 9.9
291 gigantism 9.9
292 hyperacusis 9.9
293 metatarsus adductus 9.9
294 odontoma 9.9
295 pili torti 9.9
296 encephalopathy 9.9
297 hypotonia 9.9
298 tremor 9.9
299 facial cleft 9.9
300 rare genetic skin disease 9.9
301 overgrowth syndrome 9.9
302 eec syndrome and related disorders 9.9
303 apert syndrome 9.9
304 amelogenesis imperfecta, type ia 9.9
305 popliteal pterygium syndrome 9.9
306 cleidocranial dysplasia 9.9
307 crouzon syndrome 9.9
308 ovarian cancer 9.9
309 velocardiofacial syndrome 9.9
310 schopf-schulz-passarge syndrome 9.9
311 immune deficiency disease 9.9
312 3-methylglutaconic aciduria, type iii 9.9
313 pierre robin syndrome 9.9
314 microphthalmia, syndromic 2 9.9
315 orofaciodigital syndrome i 9.9
316 axenfeld-rieger syndrome, type 3 9.9
317 branchiootic syndrome 1 9.9
318 cardiomyopathy, dilated, with woolly hair and keratoderma 9.9
319 deafness, autosomal recessive 9.9
320 orofacial cleft 5 9.9
321 gastric cancer 9.9
322 deafness, autosomal recessive 98 9.9
323 myelomeningocele 9.9
324 microphthalmia 9.9
325 fissured tongue 9.9
326 hypothyroidism 9.9
327 axenfeld-rieger syndrome 9.9
328 amelogenesis imperfecta 9.9
329 hemangioma 9.9
330 epidermolysis bullosa 9.9
331 junctional epidermolysis bullosa 9.9
332 large intestine cancer 9.9
333 dentin dysplasia 9.9
334 anthrax disease 9.9
335 periodontitis 9.9
336 alopecia 9.9
337 47,xyy 9.9
338 cleidocranial dysplasia spectrum disorder 9.9
339 irf6-related disorders 9.9
340 chromosomal triplication 9.9
341 ovarian epithelial cancer 9.9

Graphical network of the top 20 diseases related to Tooth Agenesis:



Diseases related to Tooth Agenesis

Symptoms & Phenotypes for Tooth Agenesis

Human phenotypes related to Tooth Agenesis:

59 32 (showing 6, show less)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 micrognathia 59 32 hallmark (90%) Very frequent (99-80%) HP:0000347
2 microdontia 59 32 hallmark (90%) Very frequent (99-80%) HP:0000691
3 hypoplasia of the maxilla 59 32 hallmark (90%) Very frequent (99-80%) HP:0000327
4 oligodontia 59 32 hallmark (90%) Very frequent (99-80%) HP:0000677
5 abnormality of the face 59 Very frequent (99-80%)
6 abnormality of dental morphology 59 Very frequent (99-80%)

MGI Mouse Phenotypes related to Tooth Agenesis:

46 (showing 17, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 10.41 AXIN2 BMP4 DSP EDAR EDARADD FGFR1
2 growth/size/body region MP:0005378 10.38 AXIN2 BMP4 CDH1 DSP EDAR EDARADD
3 digestive/alimentary MP:0005381 10.34 BMP4 CDH1 DSP EDAR FGFR1 IRF6
4 cellular MP:0005384 10.29 AXIN2 BMP4 CDH1 DSP EDAR FGFR1
5 behavior/neurological MP:0005386 10.27 BMP4 EDARADD FGFR1 GREM2 LRP6 MSX1
6 cardiovascular system MP:0005385 10.21 AXIN2 BMP4 CDH1 DSP EDAR FGFR1
7 embryo MP:0005380 10.21 AXIN2 BMP4 CDH1 DSP FGFR1 IRF6
8 endocrine/exocrine gland MP:0005379 10.19 AXIN2 BMP4 CDH1 EDAR EDARADD FGFR1
9 mortality/aging MP:0010768 10.18 AXIN2 BMP4 CDH1 DSP EDAR EDARADD
10 integument MP:0010771 10.17 BMP4 CDH1 DSP EDAR EDARADD FGFR1
11 limbs/digits/tail MP:0005371 10.14 AXIN2 BMP4 EDAR EDARADD FGFR1 IRF6
12 hearing/vestibular/ear MP:0005377 10 BMP4 EDARADD FGFR1 IRF6 LRP6 MSX1
13 normal MP:0002873 9.91 AXIN2 BMP4 CDH1 FGFR1 LRP6 MSX1
14 muscle MP:0005369 9.87 BMP4 DSP FGFR1 MSX1 PAX9 TGFA
15 reproductive system MP:0005389 9.81 AXIN2 BMP4 CDH1 EDAR EDARADD FGFR1
16 skeleton MP:0005390 9.77 AXIN2 BMP4 EDAR EDARADD FGFR1 GREM2
17 vision/eye MP:0005391 9.32 AXIN2 BMP4 EDAR EDARADD FGFR1 GREM2

Drugs & Therapeutics for Tooth Agenesis

Drugs for Tooth Agenesis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 22, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
2
Ibuprofen Approved Phase 4 15687-27-1 3672
3 Acetaminophen, hydrocodone drug combination Phase 4
4 Pharmaceutical Solutions Phase 4
5
Cobalt Approved, Experimental 7440-48-4 104729
6
Lithium carbonate Approved 554-13-2
7
Salicylic acid Approved, Investigational, Vet_approved 69-72-7 338
8
Miconazole Approved, Investigational, Vet_approved 22916-47-8 4189
9 Antibodies
10 Immunologic Factors
11 Immunoglobulins
12 Immunoglobulin Fc Fragments
13 Tranquilizing Agents
14 Antidepressive Agents
15 Antimanic Agents
16 Central Nervous System Depressants
17 Psychotropic Drugs
18 Antifungal Agents
19 Keratolytic Agents
20 Dermatologic Agents
21 Buchu
22 Anti-Infective Agents

Interventional clinical trials:

(showing 35, show less)
# Name Status NCT ID Phase Drugs
1 The Effectiveness of the Cytoplast Technique in Preventing Bone Loss Around Immediate Implant Placement in the Esthetic Zone. A Randomized Clinical Trial. Completed NCT01628367 Phase 4 Medications
2 A Phase III, Randomized, Controlled Clinical Trial of Lateral Ridge Augmentation Using Autogenous Bone Blocks or Xenogenic Bone Block Grafts Loaded With Recombinant Human Bone Morphogenic Protein 2 Active, not recruiting NCT01541345 Phase 3 InductOs
3 Cephalometric Indicators of Biological Responsiveness to Orthodontic Treatment of Class II/I in Growing Patients Completed NCT00248014 Phase 2
4 A Histomorphometric Analysis of New Bone Formation Following Sinus Augmentation Using Two Different Bone Graft Materials. A Pilot Study in Humans. Active, not recruiting NCT03059914 Phase 1
5 Hypodontia and Ovarian Cancer - the Connection Between Dental Agenesis and Epithelial Cancers, Especially Ovarian Cancer. Unknown status NCT01470235
6 Clinical and Radiological Outcomes Study on Astra Tech Osseospeed Tx Profile Implant Unknown status NCT01510470
7 Clinical Study on Zirconia Bridges Unknown status NCT01835834
8 Immediate and Early Loading of Hydrothermally Treated, Hydroxyapatite-Coated Dental Implants:a Controlled Randomized Prospective Clinical Study Unknown status NCT02397044
9 A Single-centre Randomised Controlled Clinical Trial of Zirconia-based Versus Metal-based Adhesive Bridges for Replacing 2 Missing Teeth or Less in Adults. Unknown status NCT01347177
10 Is a Primer Needed for Orthodontic Bonding? A Multi-centre RCT Unknown status NCT01782521
11 A Comparison of Zirconia CAD/CAM and Conventionally Fabricated Single Implant Abutments and Restorations in the Esthetic Zone: a Randomized Controlled Clinical Trial. Unknown status NCT01229995
12 Investigation of Chronic Inflammatory Processes in the Respiratory Tract and the Eyes of Male Individuals With X-linked Hypohidrotic Ectodermal Dysplasia Completed NCT01308333
13 A Pilot Study Investigating Oral Health Related Quality of Life Improvements in Removable Partial Denture Treatments for the Replacement of Missing Teeth Completed NCT01953991
14 Platform Switching vs Regular Platform Implants. One Year Results From a RCT Completed NCT02123420
15 A Comparative, Randomized, Prospective, Clinical Study to Evaluate the Facial Bone and Esthetic Outcome of Buccal Augmentation Bone Grafting Techniques in Early (Type 2) Implant Placement Completed NCT03302143
16 Frequency of Hypodontia After Chemotherapy in Childhood Cancer Survivors: A Cross Sectional Study Recruiting NCT03445026
17 Orodental Manifestations of Rare Diseases Recruiting NCT02397824
18 One-Tooth One-Time (1T1T) A Straightforward Approach to Replace Missing Teeth in the Posterior Region: a Case Series Recruiting NCT02898311
19 Comparison of Different Drilling Speed to Classify Bone Quality by Tactile Sensation on a Saw Bone Model Recruiting NCT03877419
20 Autotransplantation of Teeth With Advanced or Completed Root Development With Intraoperative Extra-corporal Apicoectomy Recruiting NCT04041518
21 Evaluation of the Efficacy of Clear Aligners in the Correction of Severe Dental Crowding Cases Combined With Premolar Extraction Versus Vestibular Fixed Orthodontic Appliances: A Randomized Clinical Controlled Trial Recruiting NCT03645356
22 A Prospective, Single-Centre, Post-Market Study to Evaluate the Use of Polyetheretherketone (PEEK) Full-Arch Implant-Supported Prostheses in the Edentulous Jaw Recruiting NCT03655990
23 Novel Use of 2-unit Cantilever Resin-bonded Bridges for Replacing Missing Molar Teeth - a Randomized Clinical Trial Recruiting NCT02239718
24 Coordination of Rare Diseases at Sanford Recruiting NCT01793168
25 REFRAME RPD Post-Market Clinical Study Active, not recruiting NCT03198520
26 Correlation Study Between Socio-economical Deprivation and Oral Health in in French Children of 9 Years of Age in 2017. A Nationwide Database Retrospective Observational Cohort Study Active, not recruiting NCT03817437
27 Extension Study of XLHED-Affected Male Subjects Treated With EDI200 in Protocol ECP-002 Active, not recruiting NCT01992289 EDI200
28 Clinical Evaluation of Chairside Computer Assisted Design/Computer Assisted Machining (CAD/CAM) Lithium Disilicate Fixed Partial Dentures (FPD) Active, not recruiting NCT03036566
29 The Effect of Platform-Matching Versus Platform-Switching Using Standard Internal Versus Tapered Internal Plus Dental Implants on Peri-implant Hard and Soft Tissue Healing Active, not recruiting NCT02536716
30 A Proof of Concept for All-ceramic Zirconia Resin Bonded Bridges for Canine, Premolar and Short Span Posterior Teeth Official Title: Enrolling by invitation NCT02793037
31 Evaluation of Retention of Metal Reinforced Polyamide Denture Base Compared to Conventional Heat Cured Acrylic Resin Denture Base in Complete Mandibular Denture Not yet recruiting NCT03385746
32 Evaluation of the Effect of Slopped Shoulder Implant Neck Versus Conventional Implant Neck Design on the Crestal Bone Level in the Maxilla: Randomized Clinical Trial (RCT) Not yet recruiting NCT03614442
33 No-preparation Resin Bonded Bridges for the Replacement of Single Missing Teeth Not yet recruiting NCT03029637
34 Clinical Assessment Of Inlay Retained Bridge Designs (Tub Shaped And Inlay Shaped) In Missing Posterior Teeth Cases. Not yet recruiting NCT03715842
35 Observational, Case-Series Study Evaluation of Bone Width and Dental Implant Stability When Using the Densah Bur™ Bone Compaction Process to Prepare Dental Implant Sites Withdrawn NCT02502058

Search NIH Clinical Center for Tooth Agenesis

Cochrane evidence based reviews: anodontia

Genetic Tests for Tooth Agenesis

Genetic tests related to Tooth Agenesis:

# Genetic test Affiliating Genes
1 Oligodontia 29

Anatomical Context for Tooth Agenesis

MalaCards organs/tissues related to Tooth Agenesis:

41
Bone, Eye, Salivary Gland, Brain, Heart, Liver, Thyroid

Publications for Tooth Agenesis

Articles related to Tooth Agenesis:

(showing 1008, show less)
# Title Authors PMID Year
1
EDA gene mutations underlie non-syndromic oligodontia. 9 38 71
19278982 2009
2
A novel missense mutation in the paired domain of human PAX9 causes oligodontia. 9 38 71
17910065 2007
3
[Novel mutations of PAX9 gene in Chinese patients with oligodontia]. 9 38 71
16191360 2005
4
A novel missense mutation in the paired domain of PAX9 causes non-syndromic oligodontia. 9 38 71
14689302 2004
5
Novel mutation in the paired box sequence of PAX9 gene in a sporadic form of oligodontia. 9 38 71
12786960 2003
6
A novel mutation in human PAX9 causes molar oligodontia. 9 38 71
11827258 2002
7
Identification of a nonsense mutation in the PAX9 gene in molar oligodontia. 9 38 71
11781684 2001
8
Haploinsufficiency of MSX1: a mechanism for selective tooth agenesis. 9 38 71
9742121 1998
9
A human MSX1 homeodomain missense mutation causes selective tooth agenesis. 9 38 71
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10
Mutations in WNT10B Are Identified in Individuals with Oligodontia. 38 71
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Loss-of-Function Mutations in the WNT Co-receptor LRP6 Cause Autosomal-Dominant Oligodontia. 38 71
26387593 2015
12
WNT10A mutations account for ¼ of population-based isolated oligodontia and show phenotypic correlations. 38 71
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13
Mutations in WNT10A are frequently involved in oligodontia associated with minor signs of ectodermal dysplasia. 38 71
23401279 2013
14
Mutations in WNT10A are present in more than half of isolated hypodontia cases. 38 71
22581971 2012
15
Pathogenic mechanisms of tooth agenesis linked to paired domain mutations in human PAX9. 38 71
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16
WNT10A mutations are a frequent cause of a broad spectrum of ectodermal dysplasias with sex-biased manifestation pattern in heterozygotes. 38 71
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17
Novel EDA mutation resulting in X-linked non-syndromic hypodontia and the pattern of EDA-associated isolated tooth agenesis. 38 71
18657636 2008
18
A novel Gln358Glu mutation in ectodysplasin A associated with X-linked dominant incisor hypodontia. 9 71
17256800 2007
19
Molecular characterization of a novel PAX9 missense mutation causing posterior tooth agenesis. 38 71
16479262 2006
20
Novel MSX1 frameshift causes autosomal-dominant oligodontia. 38 71
16498076 2006
21
A novel mutation in PAX9 causes familial form of molar oligodontia. 38 71
16333316 2006
22
A novel missense mutation of the EDA gene in a Mongolian family with congenital hypodontia. 9 71
16583127 2006
23
Novel mutation of the initiation codon of PAX9 causes oligodontia. 38 71
15615874 2005
24
A novel MSX1 mutation in hypodontia. 38 71
15264286 2004
25
Functional analysis of a mutation in PAX9 associated with familial tooth agenesis in humans. 38 71
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26
A missense mutation in PAX9 in a family with distinct phenotype of oligodontia. 38 71
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27
Novel missense mutations and a 288-bp exonic insertion in PAX9 in families with autosomal dominant hypodontia. 9 71
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28
Haploinsufficiency of PAX9 is associated with autosomal dominant hypodontia. 9 71
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29
The role of MSX1 in human tooth agenesis. 38 71
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30
MSX1 mutation is associated with orofacial clefting and tooth agenesis in humans. 38 71
10742093 2000
31
Mutation of PAX9 is associated with oligodontia. 38 71
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WNT10A mutations also associated with agenesis of the maxillary permanent canines, a separate entity. 71
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WNT10A and isolated hypodontia. 71
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A 223-kb de novo deletion of PAX9 in a patient with oligodontia. 9 38
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[Analysis of clinical features and mutation associated with oligodontia]. 9 38
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Genetic basis of tooth agenesis. 9 38
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37
Mutations in the human homeobox MSX1 gene in the congenital lack of permanent teeth. 9 38
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Dento-craniofacial phenotypes and underlying molecular mechanisms in hypohidrotic ectodermal dysplasia (HED): a review. 9 38
19029074 2008
39
Deletion of PAX9 and oligodontia: a third family and review of the literature. 9 38
18445003 2008
40
Identification of a novel missense mutation of MSX1 gene in Chinese family with autosomal-dominant oligodontia. 9 38
18374898 2008
41
[A novel mutation of MSX1 gene in a Chinese pedigree with oligodontia]. 9 38
18788550 2008
42
Investigating the etiology of multiple tooth agenesis in three sisters with severe oligodontia. 9 38
18199077 2008
43
Identification of a novel mutation in the PAX9 gene in a family affected by oligodontia and other dental anomalies. 9 38
18028048 2007
44
A novel nonsense mutation in PAX9 is associated with marked variability in number of missing teeth. 9 38
17697174 2007
45
Seckel syndrome associated with oligodontia, microdontia, enamel hypoplasia, delayed eruption, and dentin dysmineralization: a new variant? 9 38
17032400 2006
46
Exclusion of coding region mutations in MSX1, PAX9 and AXIN2 in eight patients with severe oligodontia phenotype. 9 38
16918677 2006
47
Natural selection and molecular evolution in primate PAX9 gene, a major determinant of tooth development. 9 38
16585527 2006
48
A novel c.581C>T transition localized in a highly conserved homeobox sequence of MSX1: is it responsible for oligodontia? 9 38
16682758 2006
49
Association between PAX-9 promoter polymorphisms and hypodontia in humans. 9 38
16137495 2005
50
[Functional analysis of novel mutations in PAX9 associated with familial oligodontia]. 9 38
16086281 2005
51
Novel identification of a four-base-pair deletion mutation in PITX2 in a Rieger syndrome family. 9 38
14630904 2003
52
MSX1 gene is deleted in Wolf-Hirschhorn syndrome patients with oligodontia. 9 38
14630905 2003
53
The novel polymorphic variants within the paired box of the PAX9 gene are associated with selective tooth agenesis. 9 38
11374781 2001
54
Clinical, radiographic, and genetic evaluation of a novel form of autosomal-dominant oligodontia. 9 38
11005730 2000
55
[Palmoplantar epidermal atrophy with hypokeratosis, dys- and hypotrichosis, hypodontia, enamel and dentin hypoplasia, isolated cleft palate with cleft uvula, strabismus cryptorchism and other anomalies--an undescribed ecto-mesodermal dysplasia?]. 9 38
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Oral and dental findings in emanuel syndrome. 38
30980693 2019
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Tooth agenesis patterns in Japanese orthodontic patients with nonsyndromic oligodontia. 38
31375234 2019
58
Three Rare Disease Diagnoses in One Patient through Exome Sequencing. 38
31427378 2019
59
The Era of the Genome and Dental Medicine. 38
31329043 2019
60
Oral Health-Related Quality of Life in Dutch Children Diagnosed with Oligodontia. A Cross-Sectional Study. 38
31277355 2019
61
Phenotypic confirmation of oligodontia, colorectal polyposis and cancer in a family carrying an exon 7 nonsense variant in the AXIN2 gene. 38
30671715 2019
62
Prevalence of WNT10A gene mutations in non-syndromic oligodontia. 38
30426266 2019
63
WNT10A mutations causing oligodontia. 38
31103801 2019
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BMP4 mutations in tooth agenesis and low bone mass. 38
31128441 2019
65
Prevalence and patterns of tooth agenesis in Angle class II division 2 malocclusion in Italy: A case-control study. 38
31300232 2019
66
Tooth agenesis-related GLI2 and GLI3 genes may contribute to craniofacial skeletal morphology in humans. 38
31112935 2019
67
Concurrent manifestation of oligodontia and thrombocytopenia caused by a contiguous gene deletion in 12p13.2: A three-generation clinical report. 38
30950205 2019
68
Relationship between obesity and prevalence of dental anomalies: Does body mass index play a role? 38
31246082 2019
69
The Smith-Lemli-Opitz syndrome and dentofacial anomalies diagnostic: Case reports and literature review. 38
31005410 2019
70
Impacts of oligodontia on oral health-related quality of life reported by affected children and their parents. 38
31184709 2019
71
Early prosthodontic intervention on two three-year-old twin girls with ectodermal dysplasia. 38
31246091 2019
72
Special-needs patients in pediatric dentistry: Progeroid syndrome. A case of dental management and oral rehabilitation. 38
31214300 2019
73
Biallelic variants in POLR3GL cause endosteal hyperostosis and oligodontia. 38
31089205 2019
74
A Bibliometric Analysis of Cleft Lip and Palate-Related Publication Trends From 2000 to 2017. 38
30376727 2019
75
Chromosomal imbalance in pigs showing a syndromic form of cleft palate. 38
31068123 2019
76
Using of modified rapid palate expander with miniscrews in a patient affected by ectodermic dysplasia. 38
31173044 2019
77
A novel inhibitor of nuclear factor kappa-B kinase subunit gamma mutation identified in an incontinentia pigmenti patient with syndromic tooth agenesis. 38
30913450 2019
78
[Tooth agenesis]. 38
30982737 2019
79
Genetic analysis: Wnt and other pathways in nonsyndromic tooth agenesis. 38
29969831 2019
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Au-Kline Syndrome 38
30998304 2019
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Hypohydrotic Ectodermal Dysplasia in an Indian Family. 38
30925967 2019
82
Non-syndromic cleft lip with or without palate susceptible loci is associated with tooth agenesis. 38
30578605 2019
83
Hypodontia, Oligodontia and Anodontia in West Virginia Appalachia. 38
31015306 2019
84
Follow-Up of Non-Syndromic Oligodontia With Conservative Approach. 38
31033683 2019
85
Anatomical analysis of zygomatic bone in ectodermal dysplasia patients with oligodontia. 38
30793468 2019
86
Experiences of daily life and oral rehabilitation in oligodontia - a qualitative study. 38
30646789 2019
87
Oral sequelae and rehabilitation considerations for survivors of childhood cancer. 38
30850784 2019
88
Oculo-Facio-Cardio-Dental Syndrome: A Case Report about a Rare Pathological Condition. 38
30875852 2019
89
Novel mutations identified in patients with tooth agenesis by whole-exome sequencing. 38
30417976 2019
90
Variants of the ectodysplasin A1 receptor gene underlying homozygous cases of autosomal recessive hypohidrotic ectodermal dysplasia. 38
30623979 2019
91
[Detection and functional analysis of BMP2 gene mutation in patients with tooth agenesis]. 38
30773537 2019
92
Oro-dental phenotype in patients with RUNX2 duplication. 38
29852250 2019
93
Stage- and tissue-specific effect of cyclophosphamide during tooth development. 38
30715254 2019
94
Familial oligodontia and regional odontodysplasia associated with a PAX9 initiation codon mutation. 38
30809714 2019
95
Patterns of congenitally missing teeth of non-syndromic and syndromic patients treated at a single-center over the past thirty years. 38
30496934 2019
96
Establishment of an ectodermal dysplasia related gene EDA Knockout human embryonic stem cell line (WAe001-A-22) by CRISPR-Cas9 technology. 38
30605838 2019
97
Multidisciplinary Treatment Intervention in 24 Patients with Oligodontia: A Case-Cohort Study. 38
30677108 2019
98
Novel dental phenotype in non-syndromic Pierre Robin Sequence: A retrospective study. 38
30391793 2019
99
A novel PTCH1 mutation in basal cell nevus syndrome with rare craniofacial features. 38
30962945 2019
100
KDF1 is a novel candidate gene of non-syndromic tooth agenesis. 38
30384154 2019
101
Third molar tooth agenesis and pattern of impaction in patients with palatally displaced canines. 38
30324806 2019
102
Tooth agenesis: part 2. Orthodontic treatment and prosthetic possibilities. 38
30966729 2019
103
Tooth agenesis: part 1. Incidence and diagnosis in orthodontics. 38
30759978 2019
104
Interceptive treatment in ectodermal dysplasia using an innovative orthodontic/prosthetic modular appliance. A case report with 10- year follow-up. 38
30567449 2018
105
Bi-allelic POLR3A Loss-of-Function Variants Cause Autosomal-Recessive Wiedemann-Rautenstrauch Syndrome. 38
30414627 2018
106
Non-syndromic tooth agenesis patterns and their association with other dental anomalies: A retrospective study. 38
30172942 2018
107
WNT10A variants in relation to nonsyndromic hypodontia in eastern Slovak population. 38
30555066 2018
108
What factors affect the severity of permanent tooth impaction? 38
30382922 2018
109
Patterns of Dental Agenesis Highlight the Nature of the Causative Mutated Genes. 38
29879364 2018
110
Further evidence for the role of WNT10A, WNT10B and GREM2 as candidate genes for isolated tooth agenesis. 38
30246922 2018
111
Dental implants with fixed prosthodontics in oligodontia: A retrospective cohort study with a follow-up of up to 25 years. 38
29703671 2018
112
Examination of craniofacial morphology in Japanese patients with congenitally missing teeth: a cross-sectional study. 38
30270414 2018
113
Agenesis of Permanent Canines in Orthodontic Patients: Prevalence, Location, Treatment Options and Outcomes. 38
30869590 2018
114
Homozygosity for CREB3L1 premature stop codon in first case of recessive osteogenesis imperfecta associated with OASIS-deficiency to survive infancy. 38
29936144 2018
115
Identification of likely pathogenic and known variants in TSPEAR, LAMB3, BCOR, and WNT10A in four Turkish families with tooth agenesis. 38
30046887 2018
116
Frequency of missing teeth and reduction of mesiodistal tooth width in Japanese patients with tooth agenesis. 38
30123921 2018
117
Nonsyndromic cleft lip and/or palate: A multicenter study of the dental anomalies involved. 38
30305871 2018
118
A novel mutation of MSX1 in oligodontia inhibits odontogenesis of dental pulp stem cells via the ERK pathway. 38
30134957 2018
119
Adverse effects of chemotherapy on the teeth and surrounding tissues of children with cancer: A systematic review with meta-analysis. 38
30098781 2018
120
Tooth agenesis code (TAC) in complete unilateral and bilateral cleft lip and palate patients. 38
29243181 2018
121
Associations between tooth agenesis and displaced maxillary canines: a cross-sectional radiographic study. 38
30027405 2018
122
Clinical Risk Factors Influencing Dental Developmental Disturbances in Childhood Cancer Survivors. 38
29020731 2018
123
Dental Anomalies in Different Types of Cleft Lip and Palate: Is There Any Relation? 38
29485555 2018
124
[Clinical features and mutational analysis of a case with Sensenbrenner syndrome]. 38
29896747 2018
125
Orthognathic surgery in Melnick-Needles syndrome: a review of the literature and report of two siblings. 38
29336932 2018
126
WNT10A mutation results in severe tooth agenesis in a family of three sisters. 38
29927056 2018
127
Maxillary Hypoplasia With Congenital Oligodontia Treated by Maxillary Distraction Osteogenesis. 38
29489572 2018
128
A novel PITX2 mutation in non-syndromic orodental anomalies. 38
29121437 2018
129
The Changing Landscape in the Genetic Etiology of Human Tooth Agenesis. 38
29772684 2018
130
GREM2 nucleotide variants and the risk of tooth agenesis. 38
28992378 2018
131
WNT10B mutations associated with isolated dental anomalies. 38
29364501 2018
132
Rare and Common Variants Conferring Risk of Tooth Agenesis. 38
29364747 2018
133
A biallelic ANTXR1 variant expands the anthrax toxin receptor associated phenotype to tooth agenesis. 38
29436111 2018
134
Rethinking isolated cleft lip and palate as a syndrome. 38
29500156 2018
135
Third molar agenesis as a potential marker for craniofacial deformities. 38
29358133 2018
136
Tooth agenesis: A susceptible indicator for colorectal cancer? 38
29893310 2018
137
Agenesis of all permanent maxillary incisors: A rare clinical case with an interdisciplinary solution. 38
29750104 2018
138
Long-term implant performance and patients' satisfaction in oligodontia. 38
29360491 2018
139
Dental anomalies in different growth and skeletal malocclusion patterns. 38
29215300 2018
140
Let-7b regulates alpaca hair growth by downregulating ectodysplasin A. 38
29344666 2018
141
A review on non-syndromic tooth agenesis associated with PAX9 mutations. 38
29628999 2018
142
Nine Novel PAX9 Mutations and a Distinct Tooth Agenesis Genotype-Phenotype. 38
28910570 2018
143
Genetic study of non-syndromic tooth agenesis through the screening of paired box 9, msh homeobox 1, axin 2, and Wnt family member 10A genes: a case-series. 38
29114927 2018
144
Colorectal Cancer-Associated Genes Are Associated with Tooth Agenesis and May Have a Role in Tooth Development. 38
29445242 2018
145
Mesenchymal Wnt/β-catenin signaling limits tooth number. 38
29437780 2018
146
Disturbances of dental development distinguish patients with oligodontia-ectodermal dysplasia from isolated oligodontia. 38
29271123 2018
147
Next generation sequencing reveals a novel nonsense mutation in MSX1 gene related to oligodontia. 38
30192788 2018
148
Biology Explaining Tooth Repair and Regeneration: A Mini-Review. 38
29533942 2018
149
Phenotypic Features and Salivary Parameters in Patients with Ectodermal Dysplasia: Report of Three Cases. 38
29854479 2018
150
Non-syndromic hypodontia of permanent dentition associated with other dental anomalies in children and adolescents. 38
30534829 2018
151
Diagnosis of Tooth Agenesis in Childhood and Risk for Neoplasms in Adulthood. 38
30559619 2018
152
Sanjad-Sakati Syndrome: Oral Health Care. 38
29533933 2018
153
Whole-Exome Sequencing Identifies Novel Variants for Tooth Agenesis. 38
28813618 2018
154
Investigation of prevalence of dental anomalies by using digital panoramic radiographs. 38
28933802 2018
155
Nonsyndromic cleft lip and palate, gastric cancer and tooth agenesis. 38
29274157 2018
156
Al-Awadi-Raas-Rothschild syndrome with dental anomalies and a novel WNT7A mutation. 38
28917830 2017
157
A cross-sectional analysis of the prevalence of tooth agenesis and structural dental anomalies in association with cleft type in non-syndromic oral cleft patients. 38
28681357 2017
158
Gene screening facilitates diagnosis of complicated symptoms: A case report. 38
28944914 2017
159
Three-dimensional computer-guided implant placement in oligodontia. 38
28689266 2017
160
A novel PAX9 mutation causing oligodontia. 38
28965043 2017
161
Role of WNT10A in failure of tooth development in humans and zebrafish. 38
29178643 2017
162
Associations between ectodermal dysplasia, psychological distress and quality of life in a group of adults with oligodontia. 38
28754083 2017
163
Dental and extra-oral clinical features in 41 patients with WNT10A gene mutations: A multicentric genotype-phenotype study. 38
28105635 2017
164
A Comprehensive Craniofacial Study of 22q11.2 Deletion Syndrome. 38
28732176 2017
165
A novel finding of oligodontia and ankyloglossia in a 14-year-old with Floating-Harbor syndrome. 38
29210485 2017
166
PAX9 gene mutations and tooth agenesis: A review. 38
28155232 2017
167
A novel G to A transition at initiation codon and exon-intron boundary of PAX9 identified in association with familial isolated oligodontia. 38
28847717 2017
168
Permanent tooth agenesis in individuals with non-syndromic Robin sequence: a systematic review and meta-analysis. 38
29027749 2017
169
The Biology Underlying Abnormalities of Tooth Number in Humans. 38
28783411 2017
170
Establishment of a congenital tooth agenesis related gene MSX1 knockout human embryonic stem cell lines by CRISPR-Cas9 technology. 38
29034883 2017
171
Novel EDA or EDAR Mutations Identified in Patients with X-Linked Hypohidrotic Ectodermal Dysplasia or Non-Syndromic Tooth Agenesis. 38
28981473 2017
172
Tooth Abnormalities In Individuals With Unilateral Alveolar Clefts: A Comparison Between Sides Using Cone-Beam Computed Tomography. 38
29167708 2017
173
Permanent tooth agenesis in non-syndromic Robin sequence and cleft palate: prevalence and patterns. 38
27933446 2017
174
TFAP2B mutation and dental anomalies. 38
28381879 2017
175
Craniofacial shape differs in patients with tooth agenesis: geometric morphometric analysis. 38
27464525 2017
176
Morphometric covariation between palatal shape and skeletal pattern in children and adolescents: a cross-sectional study. 38
27694577 2017
177
EDA mutation by exome sequencing in non-syndromic X-linked oligodontia. 38
28052341 2017
178
Evaluation of the skeletal and dental effects in orthodontic patients with maxillary lateral incisor agenesis. 38
28560844 2017
179
Patterns of non-syndromic permanent tooth agenesis in a large orthodontic population. 38
28288390 2017
180
Mutations in AXIN2 gene as a risk factor for tooth agenesis and cancer: A review. 38
28759178 2017
181
Acromelia-oligodontia syndrome. 38
28588849 2017
182
Contemporary surgical management of hypodontia. 38
28410841 2017
183
Oral Rehabilitation of a Patient With Ectodermal Dysplasia Treated With Fresh-Frozen Bone Allografts and Computer-Guided Implant Placement: A Clinical Case Report. 38
28208056 2017
184
Association between Tooth Agenesis and Skeletal Malocclusions. 38
28791079 2017
185
Dental anomaly patterns associated with tooth agenesis. 38
28121195 2017
186
Blepharocheilodontic (BCD) syndrome: New insights on craniofacial and dental features. 38
28181393 2017
187
Nonsyndromic oligodontia : Does the Tooth Agenesis Code (TAC) enable prediction of the causative mutation? 38
28204848 2017
188
Non-syndromic severe hypodontia caused by a novel frameshift insertion mutation in the homeobox of the MSX1 gene. 38
27951410 2017
189
Dental anomalies: prevalence and associations between them in a large sample of non-orthodontic subjects, a cross-sectional study. 38
28284207 2017
190
Management of missing mandibular second premolars: a review. 38
29709125 2017
191
Genetic Disorders of Dental Development: Tales from the Bony Crypt. 38
28124261 2017
192
Novel IRF6 Mutations Detected in Orofacial Cleft Patients by Targeted Massively Parallel Sequencing. 38
27834299 2017
193
Second premolar agenesis as a subclinical phenotype of isolated cleft palate. 38
27860241 2017
194
Pyramidal and Taurodont Molars and Their Association With Other Tooth Anomalies. 38
28292341 2017
195
Prevalence of dental anomalies in deciduous dentition and its association with succedaneous dentition: A cross-sectional study of 4180 South Indian children. 38
28139484 2017
196
Patterns of incisor-premolar agenesis combinations: A retrospective study. 38
28139483 2017
197
Comprehensive genetic exploration of selective tooth agenesis of mandibular incisors by exome sequencing. 38
28265457 2017
198
Association between EDAR Polymorphisms and Non-Syndromic Tooth Agenesis in the Chinese Han Population. 38
28808699 2017
199
Prevalence of delayed tooth development and its relation to tooth agenesis in Korean children. 38
27810381 2017
200
Characterization of PAX9 variant P20L identified in a Japanese family with tooth agenesis. 38
29023497 2017
201
WNT10A variants isolated from Japanese patients with congenital tooth agenesis. 38
29367877 2017
202
Tooth agenesis in osteogenesis imperfecta related to mutations in the collagen type I genes. 38
27510842 2017
203
Evaluation of Masticatory Stimulation Effect on the Maxillary Transversal Growth in Ectodermal Dysplasia Children. 38
28377657 2017
204
Agenesis of Third Molars among Turkish Children between the Ages of 12 and 18 Years: A Retrospective Radiographic Study. 38
28422596 2017
205
Combined Orthodontic and Restorative Approach to Esthetic Treatment of Maxillary Peg Lateral Incisor in Adolescent Female Patient: Case Report. 38
29916685 2017
206
Endodontic Management of an Infected Primary Molar in a Child with Agenesis of the Permanent Premolar. 38
28179938 2017
207
Hypodontia: An Update on Its Etiology, Classification, and Clinical Management. 38
28401166 2017
208
Influence of Deformation and Stress between Bone and Implant from Various Bite Forces by Numerical Simulation Analysis. 38
28630862 2017
209
Bmp4-Msx1 signaling and Osr2 control tooth organogenesis through antagonistic regulation of secreted Wnt antagonists. 38
27713059 2016
210
MSX1 mutations and associated disease phenotypes: genotype-phenotype relations. 38
27381090 2016
211
A novel heterozygous mutation in desmoplakin gene in a Lebanese patient with Carvajal syndrome and tooth agenesis. 38
26833927 2016
212
Tooth agenesis and orofacial clefting: genetic brothers in arms? 38
27699475 2016
213
Genetic Basis of Nonsyndromic and Syndromic Tooth Agenesis. 38
27895972 2016
214
Novel human mutation and CRISPR/Cas genome-edited mice reveal the importance of C-terminal domain of MSX1 in tooth and palate development. 38
27917906 2016
215
Dental Anomalies in a Brazilian Cleft Population. 38
26575968 2016
216
Dental anomalies in an orthodontic patient population with maxillary lateral incisor agenesis. 38
28125145 2016
217
Abnormal primary and permanent dentitions with ectodermal symptoms predict WNT10A deficiency. 38
27881089 2016
218
Novel mutations in LRP6 highlight the role of WNT signaling in tooth agenesis. 38
26963285 2016
219
Mutation analysis by direct and whole exome sequencing in familial and sporadic tooth agenesis. 38
27665865 2016
220
Effects of PAX9 and MSX1 gene variants to hypodontia, tooth size and the type of congenitally missing teeth. 38
28040065 2016
221
Role of the Wnt signaling molecules in the tooth. 38
28408959 2016
222
Characterization of a novel mutation in PAX9 gene in a family with non-syndromic dental agenesis. 38
27491081 2016
223
Association between hypodontia and Angles malocclusion. 38
27895346 2016
224
A novel MSX1 intronic mutation associated with autosomal dominant non-syndromic oligodontia in a large Chinese family pedigree. 38
27485761 2016
225
Mutation of KREMEN1, a modulator of Wnt signaling, is responsible for ectodermal dysplasia including oligodontia in Palestinian families. 38
27049303 2016
226
Genetics: The Future Is Now with Interprofessional Collaboration. 38
27671963 2016
227
Autosomal dominant Carvajal plus syndrome due to the novel desmoplakin mutation c.1678A > T (p.Ile560Phe). 38
28649555 2016
228
Midfacial Protraction With Skeletal Anchorage After Pterygomaxillary Separation. 38
27428915 2016
229
Long-term effect of chemotherapy-intensity-modulated radiation therapy (chemo-IMRT) on dentofacial development in head and neck rhabdomyosarcoma patients. 38
27689858 2016
230
Alteration of palatine ruga pattern in subjects with oligodontia: A pilot study. 38
27476363 2016
231
Multidisciplinary Management of Oligodontia in the Adolescent. 38
29182258 2016
232
De novo EDA mutations: Variable expression in two Egyptian families. 38
27054699 2016
233
[EDA mutation screening and phenotype analysis in patients with tooth agenesis]. 38
29263514 2016
234
Mutations in MSX1, PAX9 and MMP20 genes in Saudi Arabian patients with tooth agenesis. 38
27365112 2016
235
Prevalence and patterns of permanent tooth agenesis in individuals with Down syndrome: a meta-analysis. 38
27311636 2016
236
Functional analysis of a novel missense mutation in AXIN2 associated with non-syndromic tooth agenesis. 38
27090353 2016
237
Rehabilitation of a patient with non-syndromic partial oligodontia. 38
27350861 2016
238
Hypodontia, a prospective predictive marker for tumor? 38
26600092 2016
239
Waardenburg syndrome type I: Dental phenotypes and genetic analysis of an extended family. 38
27031059 2016
240
A Digital Approach to Improved Overdentures for the Adolescent Oligodontia Patient. 38
27154432 2016
241
Prosthodontic Rehabilitation with a Telescopic Prosthesis of a Nonsyndromic Oligodontia Patient. 38
26032146 2016
242
Early functional, esthetic, and psychological rehabilitation of preschool child with nonsyndromic oligodontia and anodontia in mixed dentition stage through conservative systematic approach: A case report with 5-year follow-up. 38
27307674 2016
243
WNT10A polymorphism may be a risk factor for non-syndromic hypodontia. 38
27050986 2016
244
Odonto-onycho-dermal dysplasia in a patient homozygous for a WNT10A nonsense mutation and mild manifestations of ectodermal dysplasia in carriers of the mutation. 38
26964878 2016
245
Clinical and Radiographic Evaluation of a Small-Diameter Dental Implant Used for the Restoration of Patients with Permanent Tooth Agenesis (Hypodontia) in the Maxillary Lateral Incisor and Mandibular Incisor Regions: A 36-Month Follow-Up. 38
26929953 2016
246
A targeted next-generation sequencing assay for the molecular diagnosis of genetic disorders with orodental involvement. 38
26502894 2016
247
[EDA mutation screening and phenotype analysis in patients with tooth agenesis]. 38
27538153 2016
248
Functional Study of Ectodysplasin-A Mutations Causing Non-Syndromic Tooth Agenesis. 38
27144394 2016
249
DNA methylation is critical for tooth agenesis: implications for sporadic non-syndromic anodontia and hypodontia. 38
26759063 2016
250
Genetic Variants of BMP2 and Their Association with the Risk of Non-Syndromic Tooth Agenesis. 38
27362534 2016
251
Carvajal syndrome with oligodontia, hypoacusis, recurrent infections, and noncompaction. 38
26599742 2016
252
Antineoplastic chemotherapy and congenital tooth abnormalities in children and adolescents. 38
28373822 2016
253
Dental anomalies inside the cleft region in individuals with nonsyndromic cleft lip with or without cleft palate. 38
26615505 2016
254
The association between WNT10A variants and dental development in patients with isolated oligodontia. 38
27650966 2016
255
Possible association between acetazolamide administration during pregnancy and multiple congenital malformations. 38
27143854 2016
256
Antagonistic Functions of USAG-1 and RUNX2 during Tooth Development. 38
27518316 2016
257
Novel missense mutation in the EDA gene in a family affected by oligodontia. 38
26753551 2016
258
Symmetrical agenesis of the mandibular third molars and agenesis of other teeth in a Japanese orthodontic population. 38
27349537 2016
259
Diagnosis and Management of a Patient with Congenitally Missing Maxillary First Permanent Molars: A Rare Case Report. 38
27525130 2016
260
Patterns of bilateral agenesis of maxillary third molars and agenesis of other teeth. 38
25636272 2016
261
A novel initiation codon mutation of PAX9 in a family with oligodontia. 38
26571067 2016
262
Surgically Assisted Orthodontics: Use of Piezocision in a Case of Oligodontia to Accelerate the Rate of Tooth Movement. 38
27319046 2016
263
A simplified approach for prosthodontic management of syndromic oligodontia. 38
26858479 2015
264
Gene responsible for oligodontia found, say researchers. 38
26942238 2015
265
[Investigation of teeth number and morphology abnormalities in children at the mixed dentition stage]. 38
27051952 2015
266
GREMLIN 2 Mutations and Dental Anomalies. 38
26416033 2015
267
Prevalence and distribution of dental anomalies: a comparison between maxillary and mandibular tooth agenesis. 38
26522039 2015
268
Permanent Tooth Agenesis and Maxillary Hypoplasia in Patients with Unilateral Cleft Lip and Palate. 38
26505722 2015
269
Ultra-Thin Veneers Without Tooth Preparation in Extensive Oligodontia. 38
26509995 2015
270
Mesiodistal inclination of the unerupted second premolar in the mandible of Japanese orthodontic patients with incisor agenesis. 38
25757185 2015
271
Intermediate rehabilitation with (non)-prep all-ceramic onlays in an adolescent patient with oligodontia--4-year follow-up. 38
25109372 2015
272
A multidisciplinary treatment of patients with craniofacial disorders. Own experience. 38
26982754 2015
273
Prosthodontic Treatment for Severe Oligodontia with Long-term Follow-up. 38
26485508 2015
274
Further delineation of the KBG syndrome phenotype caused by ANKRD11 aberrations. 38
25424714 2015
275
Genetic epidemiology of tooth agenesis in Japan: a population- and family-based study. 38
25041097 2015
276
Noninvasive Prenatal Diagnosis of Hypohidrotic Ectodermal Dysplasia by Tooth Germ Sonography. 38
25140498 2015
277
Beni Solow Award 2014. 38
26209690 2015
278
A novel frameshift MSX1 mutation in a Saudi family with autosomal dominant premolar and third molar agenesis. 38
25874811 2015
279
Bilateral Hypodontia in Adolescents With Pierre Robin Sequence. 38
25058123 2015
280
Prevalence and patterns of tooth agenesis in Angle Class II Division 2 malocclusion in Japan. 38
26124035 2015
281
The Gene Network Underlying Hypodontia. 38
25910507 2015
282
Erratum to: Living with orofacial conditions: psychological distress and quality of life in adults affected with Treacher Collins syndrome, cherubism, or oligodontia/ectodermal dysplasia--a comparative study. 38
25480422 2015
283
The functional EGF+61 polymorphism and nonsyndromic oral clefts susceptibility in a Brazilian population. 38
26398511 2015
284
New recessive truncating mutation in LTBP3 in a family with oligodontia, short stature, and mitral valve prolapse. 38
25899461 2015
285
Association of BMP4 polymorphisms with isolated tooth agenesis in a Chinese Han population: a case-control study. 38
26166641 2015
286
A Nonsyndromic Autosomal Dominant Oligodontia with A Novel Mutation of PAX9-A Clinical and Genetic Report. 38
26266225 2015
287
Relationship between the maxillary transverse dimension and palatally displaced canines: A cone-beam computed tomographic study. 38
25098187 2015
288
An AXIN2 Mutant Allele Associated With Predisposition to Colorectal Neoplasia Has Context-Dependent Effects on AXIN2 Protein Function. 38
26025668 2015
289
Agenesis of multiple primary and permanent teeth unilaterally and its possible management. 38
26028909 2015
290
An evaluation of clinical, radiological and three-dimensional dental tomography findings in ectodermal dysplasia cases. 38
25662550 2015
291
Living with orofacial conditions: psychological distress and quality of life in adults affected with Treacher Collins syndrome, cherubism, or oligodontia/ectodermal dysplasia-a comparative study. 38
25344415 2015
292
Identical deletion at 14q13.3 including PAX9 and NKX2-1 in siblings from mosaicism of unaffected parent. 38
25608831 2015
293
Familial Hypodontia: A Case Series. 38
26643836 2015
294
A screen of a large Czech cohort of oligodontia patients implicates a novel mutation in the PAX9 gene. 38
25683653 2015
295
Limitations of a method used for adolescent assessment of smile aesthetics. 38
25016580 2015
296
Dental implants are a viable alternative for compensating oligodontia in adolescents. 38
24383943 2015
297
Axis inhibition protein 2 polymorphisms may be a risk factor for families with isolated oligodontia. 38
25377791 2015
298
Distribution of permanent canine agenesis in Down syndrome: 15 cases from a Centre for Special Care Dentistry. 38
25081021 2015
299
Determination of vertical dimension in prosthodontic rehabilitation of a growing patient with severe oligodontia. 38
25793956 2015
300
An interdisciplinary noninvasive all-ceramic treatment concept for nonsyndromic oligodontia in adolescence. 38
25191671 2015
301
[BMP2/BMP4 genetic evaluation in 40 patients with tooth agenesis]. 38
25858375 2015
302
[Optimization of diagnostics and orthodontic treatment planning in children and adolescents with multiply adentia]. 38
26331177 2015
303
The prevalence of dental anomalies in a turkish population. 38
28955542 2015
304
[In Process Citation]. 38
26631270 2015
305
An aberrant splice acceptor site due to a novel intronic nucleotide substitution in MSX1 gene is the cause of congenital tooth agenesis in a Japanese family. 38
26030286 2015
306
Prevalence of tooth agenesis in adolescent Chinese populations with or without orthodontics. 38
25815384 2015
307
Novel PAX9 gene polymorphisms and mutations and susceptibility to tooth agenesis in the Czech population. 38
26707046 2015
308
Retrospective Study of Association between Displacement of Maxillary Canine and Tooth Agenesis. 38
26551375 2015
309
Taurodontism, variations in tooth number, and misshapened crowns in Wnt10a null mice and human kindreds. 38
25629078 2015
310
Oligodontia in a teenager with Down syndrome - a case study. 38
25338122 2015
311
A Novel AXIN2 Missense Mutation Is Associated with Non-Syndromic Oligodontia. 38
26406231 2015
312
Association between third molar agenesis patterns and agenesis of other teeth in a Japanese orthodontic population. 38
23990107 2015
313
Maxillary dental anomalies in patients with cleft lip and palate: a cone beam computed tomography study. 38
25823490 2015
314
Simultaneous Occurence of an Autosomal Dominant Inherited MSX1 Mutation and an X-linked Recessive Inherited EDA Mutation in One Chinese Family with Non-syndromic Oligodontia. 38
26629556 2015
315
Local anesthetics induce autophagy in young permanent tooth pulp cells. 38
27551457 2015
316
Bilateral agenesis of maxillary permanent canines: Review of the literature. 38
25657989 2015
317
Conventional Complete Denture in Patients with Ectodermal Dysplasia. 38
26425372 2015
318
Prevalence of hypodontia and associated factors: a systematic review and meta-analysis. 38
25404667 2014
319
Interstitial 12p deletion involving more than 40 genes in a patient with postnatal microcephaly, psychomotor delay, optic nerve atrophy, and facial dysmorphism. 38
25606391 2014
320
Intragenic duplication--a novel causative mechanism for SATB2-associated syndrome. 38
25251319 2014
321
Skeletal malocclusion: a developmental disorder with a life-long morbidity. 38
25247012 2014
322
[WNT 10A-mutations as explanation for tooth agenesis]. 38
26188476 2014
323
Autogenous premolar transplantation into artificial socket in maxillary lateral incisor site. 38
25134733 2014
324
Association of MSX1 and TGF-β1 genetic polymorphisms with hypodontia: meta-analysis. 38
25501212 2014
325
PAX-9 polymorphism may be a risk factor for hypodontia: a meta-analysis. 38
25501211 2014
326
Mutations in the MSX1 gene in Turkish children with non-syndromic tooth agenesis and other dental anomalies. 38
25565750 2014
327
A study of prevalence and distribution of tooth agenesis. 38
25713620 2014
328
The WNT10A gene in ectodermal dysplasias and selective tooth agenesis. 38
24700731 2014
329
Orodental manifestations in ectodermal dysplasia-a review. 38
24719393 2014
330
Msx1 role in craniofacial bone morphogenesis. 38
24929242 2014
331
Variability in dentofacial phenotypes in four families with WNT10A mutations. 38
24398796 2014
332
Non-syndromic oligodontia in permanent dentition: a case report. 38
25709129 2014
333
A novel non-stop mutation in MSX1 causing autosomal dominant non-syndromic oligodontia. 38
24914010 2014
334
Implant-retained overdentures for young children with severe oligodontia: a series of four cases. 38
25109582 2014
335
Using implants for prosthodontic rehabilitation of a 4-year-old with ectodermal dysplasia. 38
25184725 2014
336
Dento-maxillo-facial phenotype and implants-based oral rehabilitation in Ectodermal Dysplasia with WNT10A gene mutation: report of a case and literature review. 38
24702986 2014
337
From childhood to adulthood: oral rehabilitation of a patient with ectodermal dysplasia. 38
24831743 2014
338
Bilateral maxillary canine-first premolar transposition in permanent dentition. 38
25149842 2014
339
Bilateral hypodontia is more common than unilateral hypodontia in children with Down syndrome: a prospective population-based study. 38
24014738 2014
340
Assessing the association of taurodontism with numeric dentition anomalies in an adult central Indian population. 38
25097429 2014
341
Labial ankyloglossia associated with oligodontia: a case report. 38
25584061 2014
342
A novel WNT10A mutation causes non-syndromic hypodontia in an Egyptian family. 38
24798981 2014
343
Nonsyndromic oligodontia in siblings: A rare case report. 38
25210374 2014
344
Esthetic rehabilitation of a patient with severe oligodontia. 38
24502758 2014
345
Evaluation of tooth number anomalies in a subpopulation of the North-East of Turkey. 38
25202213 2014
346
Bilateral agenesis of permanent mandibular central incisors: report of two cases. 38
25083043 2014
347
Blepharo-cheilo-dontic (BCD) syndrome: expanding the phenotype, case report and review of literature. 38
24719364 2014
348
Wolf-Hirschhorn syndrome (WHS) - literature review on the features of the syndrome. 38
24979523 2014
349
EDAR-induced hypohidrotic ectodermal dysplasia: a clinical study on signs and symptoms in individuals with a heterozygous c.1072C > T mutation. 38
24884697 2014
350
Exclusion of PAX9 and MSX1 mutation in six families affected by tooth agenesis. A genetic study and literature review. 38
24316698 2014
351
Identification of genetic risk factors for maxillary lateral incisor agenesis. 38
24554542 2014
352
[Association between AXIN2 polymorphism and oligodontia]. 38
24743819 2014
353
Interdisciplinary treatment of a nonsyndromic oligodontia patient with implant-anchored orthodontics. 38
24680022 2014
354
Complex analysis of multiple single nucleotide polymorphisms as putative risk factors of tooth agenesis in the Hungarian population. 38
23964635 2014
355
Association between rs11001553 of DKK1 and non-syndromic tooth agenesis in the Chinese Han population. 38
24737523 2014
356
Oligodontia and curly hair occur with ectodysplasin-a mutations. 38
24487376 2014
357
Prevalence and patterns of permanent tooth agenesis in patients with nonsyndromic Pierre Robin sequence. 38
24703283 2014
358
Tricho-odonto-onycho-dermal dysplasia and WNT10A mutations. 38
24458874 2014
359
Three novel GJA1 missense substitutions resulting in oculo-dento-digital dysplasia (ODDD) - further extension of the mutational spectrum. 38
24508941 2014
360
Is there a link between ovarian cancer and tooth agenesis? 38
24631698 2014
361
Prevalence of second premolar hypodontia in the Polish cleft lip and palate population. 38
24584216 2014
362
Patterns of tooth agenesis in patients with crouzon or apert syndrome. 38
23126314 2014
363
Colorectal cancer and self-reported tooth agenesis. 38
24607150 2014
364
Rehabilitation of medically complex ectodermal dysplasia with novel surgical and prosthodontic protocols. 38
24035129 2014
365
Prevalence and patterns of tooth agenesis among Malay children. 38
24968691 2014
366
Prevalence of dental anomalies among 7- to 35-year-old people in Hamadan, Iran in 2012-2013 as observed using panoramic radiographs. 38
24701453 2014
367
Novel PAX9 mutations cause non-syndromic tooth agenesis. 38
24436340 2014
368
Novel missense mutations in the AXIN2 gene associated with non-syndromic oligodontia. 38
24581859 2014
369
Genetic basis of dental agenesis--molecular genetics patterning clinical dentistry. 38
24121910 2014
370
Deep submersion: severe phenotype of deciduous-molar infraocclusion with biological associations. 38
24001108 2014
371
Ion channels, channelopathies, and tooth formation. 38
24076519 2014
372
Novel nonsense mutation in MSX1 in familial nonsyndromic oligodontia: subcellular localization and role of homeodomain/MH4. 38
24329876 2014
373
Tooth agenesis patterns and phenotype variation in a cohort of Belgian patients with hypodontia and oligodontia clustered in 79 families with their pedigrees. 38
23598609 2014
374
Whole genome sequencing reveals novel non-synonymous mutation in ectodysplasin A (EDA) associated with non-syndromic X-linked dominant congenital tooth agenesis. 38
25203534 2014
375
Clinical and genetic analysis of a nonsyndromic oligodontia in a child. 38
25215247 2014
376
A novel PITX2 mutation causing iris hypoplasia. 38
27081499 2014
377
Unilateral maxillary canine agenesis: a case report and literature review. 38
25177502 2014
378
WNT10A variants are associated with non-syndromic tooth agenesis in the general population. 38
24043634 2014
379
Characterization of novel MSX1 mutations identified in Japanese patients with nonsyndromic tooth agenesis. 38
25101640 2014
380
A rare case of osteogenesis imperfecta combined with complete tooth loss. 38
23934635 2014
381
IRF6 AP-2a binding site promoter polymorphism is associated with oral clefts in Latvia. 38
25896037 2014
382
A newly identified missense mutation of the EDA1 gene in a Hungarian patient with Christ-Siemens-Touraine syndrome. 38
23989902 2014
383
Molecular patterning of the mammalian dentition. 38
24355560 2014
384
A genome-wide association study of third molar agenesis in Japanese and Korean populations. 38
24172245 2013
385
Candidate gene studies in hypodontia suggest role for FGF3. 38
23549991 2013
386
Prosthodontic management of a patient with ectodermal dysplasia. 38
24304998 2013
387
Different manifestations of class II division 2 incisor retroclination and their association with dental anomalies. 38
24297961 2013
388
MSX1 and PAX9 investigation in monozygotic twins with variable expression of tooth agenesis. 38
24103583 2013
389
A comparison of skeletal maturation in patients with tooth agenesis and unaffected controls assessed by the cervical vertebral maturation (CVM) index. 38
24297960 2013
390
Nucleotide variants of genes encoding components of the Wnt signalling pathway and the risk of non-syndromic tooth agenesis. 38
23167694 2013
391
Associations between the risk of tooth agenesis and single-nucleotide polymorphisms of MSX1 and PAX9 genes in nonsyndromic cleft patients. 38
23718693 2013
392
[Analysis of dental agenesis patterns of the oligodontia patients using the method of tooth agenesis code]. 38
24513068 2013
393
Discordant tooth agenesis and peg-shaped in a pair of monozygotic twins: Clinical and molecular study. 38
24379875 2013
394
Developmental disorders of the dentition: an update. 38
24124058 2013
395
Bilateral missing lower permanent incisors: a case report. 38
24380140 2013
396
BMP4 Polymorphism is Associated With Nonsyndromic Oral Cleft in a Brazilian Population. 38
23237431 2013
397
Mutational analysis of AXIN2, MSX1, and PAX9 in two Mexican oligodontia families. 38
24222224 2013
398
Prosthodontic rehabilitation in patient with ectodermal dysplasia combining preprosthetic techniques: a case report. 38
24013396 2013
399
An inductive signalling network regulates mammalian tooth morphogenesis with implications for tooth regeneration. 38
23952789 2013
400
A 3-year prospective study of implant-supported, single-tooth restorations of all-ceramic and metal-ceramic materials in patients with tooth agenesis. 38
22708959 2013
401
PAX9 polymorphisms and susceptibility with sporadic tooth agenesis in Turkish populations: a case-control study. 38
24160254 2013
402
Novel PAX9 mutation associated with syndromic tooth agenesis. 38
24028587 2013
403
Msx1 Gene Variant - its Association in Isolated Hypodontia: A Case Control Genetic study!!! 38
24497713 2013
404
MSX1 gene variant - its presence in tooth absence - a case control genetic study. 38
24324300 2013
405
Achondroplasia with oligodontia: Report of a rare case. 38
24574672 2013
406
Patient with oligodontia treated with a miniscrew for unilateral mesial movement of the maxillary molars and alignment of an impacted third molar. 38
23992816 2013
407
Clinical and genetic evaluation of a Chinese family with isolated oligodontia. 38
23731659 2013
408
The prevalence and distribution pattern of hypodontia among orthodontic patients in Southern Iran. 38
24966733 2013
409
Isolated oligodontia in monozygotic twins. 38
24966717 2013
410
A network of transcription factors operates during early tooth morphogenesis. 38
23754753 2013
411
[Identification of mutation in PAX9 gene in a Mongolian family with non-syndromic oligodontia]. 38
24238416 2013
412
Functional evaluation of a novel tooth agenesis-associated bone morphogenetic protein 4 prodomain mutation. 38
23841782 2013
413
[Research progress on gene involved in tooth agenesis]. 38
23991591 2013
414
Patterns of tooth agenesis in patients with orofacial clefts. 38
23841784 2013
415
Patterns of tooth agenesis in Japanese subjects with bilateral agenesis of mandibular second premolars. 38
22832847 2013
416
Prevalence of Dental Anomalies in Patients With Nonsyndromic Cleft Lip and/or Palate in a Brazilian Population. 38
21973329 2013
417
Genetic background of nonsyndromic oligodontia: a systematic review and meta-analysis. 38
23828301 2013
418
Tooth agenesis patterns in unilateral cleft lip and palate in humans. 38
23295124 2013
419
Comparison of mesiodistal crown dimension and arch width in subjects with and without hypodontia. 38
23773516 2013
420
Three-dimensional analysis of tooth dimensions in the MSX1-missense mutation. 38
22936299 2013
421
Dental anomalies in a Portuguese population. 38
23541047 2013
422
The impact of tooth agenesis on oral health-related quality of life in children. 38
23794692 2013
423
Non-syndromic tooth agenesis associated with a nonsense mutation in ectodysplasin-A (EDA). 38
23603338 2013
424
Risk factors to cause tooth formation anomalies in chemotherapy of paediatric cancers. 38
23336315 2013
425
Recessive oligodontia linked to a homozygous loss-of-function mutation in the SMOC2 gene. 38
23317772 2013
426
Immediate loading rehabilitation of a severe oligodontia: minimum impact on a young patient's social life. 38
23588213 2013
427
Non-syndromic oligodontia of primary and permanent dentition: 5 year follow up- a rare case report. 38
23730675 2013
428
[Sandwich osteotomy--a biologic method for vertical augmentation of edentulous alveolar ridges]. 38
24020241 2013
429
Prosthetic rehabilitation interventions in adolescents with fixed bridges: a 5-year observational study. 38
23597223 2013
430
Dental and maxillofacial characteristics of six Japanese individuals with ectrodactyly-ectodermal dysplasia-clefting syndrome. 38
22236363 2013
431
Prevalence of tooth agenesis in orthodontic patient population in Western New York. 38
23691726 2013
432
Tooth agenesis association with self-reported family history of cancer. 38
23169889 2013
433
Genetics of tooth agenesis: how to move the field forward. 38
23857660 2013
434
Nonsyndromic tooth agenesis patterns and associated developmental dental anomalies: a literature review with radiographic illustrations. 38
23446448 2013
435
Genetic variations in MMP9 and MMP13 contribute to tooth agenesis in a Brazilian population. 38
24351915 2013
436
rs929387 of GLI3 is involved in tooth agenesis in Chinese Han population. 38
24278334 2013
437
Novel missense mutation in PAX9 gene associated with familial tooth agenesis. 38
22747565 2013
438
Candidate gene analysis of tooth agenesis identifies novel mutations in six genes and suggests significant role for WNT and EDA signaling and allele combinations. 38
23991204 2013
439
Evaluation of tooth size in patients with congenitally-missing teeth. 38
23487169 2013
440
The original family revisited after 37 years: odontoma-dysphagia syndrome is most likely caused by a microduplication of chromosome 11q13.3, including the FGF3 and FGF4 genes. 38
22297612 2013
441
Involvement of and interaction between WNT10A and EDA mutations in tooth agenesis cases in the Chinese population. 38
24312213 2013
442
Multidisciplinary therapy of extensive oligodontia: a case report. 38
23780360 2013
443
Prosthetic rehabilitation in children: an alternative clinical technique. 38
24175103 2013
444
Aesthetic rehabilitation of oligodontia in primary dentition with adhesive partial denture. 38
24319602 2013
445
Nonsyndromic familial oligodontia with multiple dens invaginatus: a case report of an unusual case. 38
24319603 2013
446
PAX9 polymorphism and susceptibility to sporadic non-syndromic severe anodontia: a case-control study in southwest China. 38
23857653 2013
447
Association of agenesis of mandibular lateral incisors with other dental anomalies in a Japanese population. 38
23595238 2013
448
Developmental basis of toothlessness in turtles: insight into convergent evolution of vertebrate morphology. 38
23289576 2013
449
[Severe hypodontia in permanent dentition. Orthodontic treatment of oligodontia in children]. 38
23387131 2012
450
Studies on dentition and oral disorders of Camels in Maiduguri Abattoir, Borno State, Nigeria. 38
22573007 2012
451
Oligodontia with taurodontism in monozygous twins. 38
23272313 2012
452
Molecular factors resulting in tooth agenesis and contemporary approaches for regeneration: a review. 38
23235129 2012
453
A novel SPRY2 and SPRY4 interaction increases tooth agenesis susceptibility. 38
25460790 2012
454
Long-term follow-up of implant treatment for oligodontia in an actively growing individual: a clinical report. 38
23107235 2012
455
Dental anomalies in children born with clefts: a case-control study. 38
21740171 2012
456
Expanding the phenotype associated with a desmoplakin dominant mutation: Carvajal/Naxos syndrome associated with leukonychia and oligodontia. 38
22795705 2012
457
Phenotype characterization and sequence analysis of BMP2 and BMP4 variants in two Mexican families with oligodontia. 38
23079991 2012
458
Non syndromic oligodontia: case report. 38
23209359 2012
459
Is missing maxillary lateral incisor in complete cleft lip and palate a product of genetics or local environment? 38
22612415 2012
460
Multidisciplinary approach for the aesthetic treatment of maxillary lateral incisors agenesis: thinking about implants? 38
23083483 2012
461
A case-control study of the association between tooth-development gene polymorphisms and non-syndromic hypodontia in the Chinese Han population. 38
22984994 2012
462
Polymorphism in the MSX1 gene in a family with upper lateral incisor agenesis. 38
22591773 2012
463
From the transcription of genes involved in ectodermal dysplasias to the understanding of associated dental anomalies. 38
23239958 2012
464
Oligodontia--treatment planning of a case. 38
23951748 2012
465
Association of common PAX9 variants with permanent tooth size variation in non-syndromic East Asian populations. 38
22810112 2012
466
Relationship between dental anomalies and orthodontic root resorption of upper incisors. 38
21745825 2012
467
Phenotypic findings in Chinese families with X-linked hypohydrotic ectodermal dysplasia. 38
22633615 2012
468
Famlial nonsyndromic oligodontia. 38
23230360 2012
469
Esthetic and functional rehabilitation for oligodontia in the mixed dentition: case report. 38
23433626 2012
470
Orthognathic surgery of a patient with oligodontia: alternative technique for intermaxillary fixation. 38
22976687 2012
471
Implant-prosthetic rehabilitation of a patient with nonsyndromic oligodontia: a clinical report. 38
21905913 2012
472
Tooth transposition: a descriptive study in a 547-patient sample. 38
22906375 2012
473
Isolated aglossia congenita: A rare case of oromandibular limb hypogenesis syndrome type I B. 38
23248477 2012
474
Oral manifestations of patients with Kenny-Caffey Syndrome. 38
22522175 2012
475
Novel nonsense mutation in MSX1 causes tooth agenesis with cleft lip in a Chinese family. 38
22813217 2012
476
Taurodontism in Brazilian patients with tooth agenesis and first and second-degree relatives: a case-control study. 38
22647425 2012
477
POLR3-Related Leukodystrophy 38
22855961 2012
478
Dental anomalies in Richieri-Costa-Pereira syndrome. 38
22727098 2012
479
The use of onplants and implants in children with severe oligodontia: a retrospective evaluation. 38
21631598 2012
480
Novel missense mutations in PAX9 causing oligodontia. 38
22277187 2012
481
Novel MSX1 mutation in a family with autosomal-dominant hypodontia of second premolars and third molars. 38
22297032 2012
482
Tooth agenesis in a Portuguese population. 38
22541886 2012
483
Defining predictors of cleft lip and palate risk. 38
22496123 2012
484
Dental developmental disturbances in 50 individuals with the 22q11.2 deletion syndrome; relation to medical conditions? 38
22070626 2012
485
Tooth size reduction and agenesis associated with palatally displaced canines. 38
22795154 2012
486
NEMO syndrome (incontinentia pigmenti) and systemic lupus erythematosus: a new disease association. 38
22235006 2012
487
Evidence for genetic heterogeneity in Carvajal syndrome. 38
22350851 2012
488
Left-sided predominance of hypodontia irrespective of cleft sidedness in a French population. 38
21905908 2012
489
TGFB3 and BMP4 polymorphism are associated with isolated tooth agenesis. 38
22191848 2012
490
A novel nonsense mutation in PAX9 is associated with sporadic hypodontia. 38
22058014 2012
491
Dental manifestations of a pediatric patient with hyperimmunoglobulin e syndrome: a case report. 38
22828767 2012
492
Root resorption of primary molars without successor teeth. An experimental study in the beagle dog. 38
22409221 2012
493
Multidisciplinary treatment of non-syndromic oligodontia. 38
22509127 2012
494
Dentistry and molecular biology: a promising field for tooth agenesis management. 38
22452934 2012
495
Prevalence and intra-oral distribution of agenesis of permanent teeth among Eastern Turkish children. 38
22455529 2012
496
Dental impactions related to pseudoxanthoma elasticum. 38
22374064 2012
497
TBX22 mutation associated with cleft lip/palate, hypodontia, and limb anomaly. 38
21375406 2012
498
Prevalence of dental anomalies in nonsyndromic individuals with cleft lip and palate: a systematic review and meta-analysis. 38
21740173 2012
499
Revision of "A 223-kb de novo deletion of PAX9 in a patient with oligodontia". 38
22446453 2012
500
Radiographic study of prevalence and distribution of hypodontia in a pediatric orthodontic population in Venezuela. 38
22583882 2012
501
Phacomatosis spilorosea with oligodontia, scoliosis and fibrous cortical defects. 38
21435028 2012
502
Disturbed dental development of permanent teeth in children with solid tumors and lymphomas. 38
21254371 2012
503
Surgical and implant-supported fixed prosthetic treatment of a patient with ectodermal dysplasia: a case report. 38
22229591 2012
504
Fahr's disease with oral manifestations: report of a rare case. 38
22472706 2012
505
Hypohidrotic ectodermal dysplasia: a multidisciplinary approach. 38
23586278 2012
506
Interaction between IRF6 and TGFA genes contribute to the risk of nonsyndromic cleft lip/palate. 38
23029012 2012
507
Patients with oro-facial clefts have more dental anomalies. 38
23059923 2012
508
An insight into the genesis of hypohidrotic ectodermal dysplasia in a case report. 38
23316396 2012
509
Novel PAX9 and COL1A2 missense mutations causing tooth agenesis and OI/DGI without skeletal abnormalities. 38
23227268 2012
510
Homozygosity mapping and candidate prioritization identify mutations, missed by whole-exome sequencing, in SMOC2, causing major dental developmental defects. 38
22152679 2011
511
Understanding the implications of the PAX9 gene in tooth development. 38
22185249 2011
512
Patterns of third-molar agenesis and associated dental anomalies in an orthodontic population. 38
22133951 2011
513
Recessive mutations in POLR3B, encoding the second largest subunit of Pol III, cause a rare hypomyelinating leukodystrophy. 38
22036172 2011
514
A novel heterozygous point mutation in the p63 gene in a patient with ectodermal dysplasia associated with B-cell leukemia. 38
21906144 2011
515
Severe oligodontia and dental anomalies in a child with a history of multiple natal teeth: An eight-year retrospective. 38
22313932 2011
516
Dental development and tooth agenesis in children with velocardiofacial syndrome. 38
21689177 2011
517
Sequence analysis of PAX9, MSX1 and AXIN2 genes in a Chinese oligodontia family. 38
21530942 2011
518
Tooth agenesis. 38
22679169 2011
519
A rat model of hypohidrotic ectodermal dysplasia carries a missense mutation in the Edaradd gene. 38
22013926 2011
520
Review of ectodermal dysplasia: case report on treatment planning and surgical management of oligodontia with implant restorations. 38
21844814 2011
521
Ellis van Creveld syndrome--a report of two siblings. 38
22675019 2011
522
Genetic basis for tooth malformations: from mice to men and back again. 38
21819395 2011
523
Maxillary sagittal growth evaluated on dry skulls from children and adolescents. 38
21395472 2011
524
Mutations of POLR3A encoding a catalytic subunit of RNA polymerase Pol III cause a recessive hypomyelinating leukodystrophy. 38
21855841 2011
525
Clinical and functional data implicate the Arg(151)Ser variant of MSX1 in familial hypodontia. 38
21448236 2011
526
Isolated oligodontia associated with mutations in EDARADD, AXIN2, MSX1, and PAX9 genes. 38
21626677 2011
527
Correlation between the phenotypes and genotypes of X-linked hypohidrotic ectodermal dysplasia and non-syndromic hypodontia caused by ectodysplasin-A mutations. 38
21457804 2011
528
Oral features in five adult patients with Wolf-Hirschhorn syndrome. 38
21709654 2011
529
Prevalence and distribution of selected developmental dental anomalies in an Indian population. 38
21712629 2011
530
Dental agenesis patterns of permanent teeth in Apert syndrome. 38
21564313 2011
531
Assessment of dental anomalies on panoramic radiographs: inter- and intraexaminer agreement. 38
20798209 2011
532
Multidisciplinary approach to a nonsyndromic oligodontia patient using advanced surgical techniques. 38
21556386 2011
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[Prosthodontic treatment of congenital tooth agenesis III. Prosthodontic principles of congenital tooth agenesis]. 38
21733387 2011
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MMP1 and MMP20 contribute to tooth agenesis in humans. 38
21144496 2011
535
The genetic basis of tooth agenesis: basic concepts and genes involved. 38
21911943 2011
536
Severe hypodontia: identifying patterns of human tooth agenesis. 38
20660128 2011
537
AXIN2-associated autosomal dominant ectodermal dysplasia and neoplastic syndrome. 38
21416598 2011
538
Congenitally missing lateral incisors--a comparison between restorative, implant, and orthodontic approaches. 38
21473994 2011
539
PAX9 and MSX1 transcription factor genes in non-syndromic dental agenesis. 38
21111400 2011
540
Endodontic management in oculo-facio-cardio-dental syndrome: a case report. 38
21419309 2011
541
Application of orthodontic mini-implants and ligation for absolute skeletal anchorage to the intraoral labiolingual appliance: midface distraction osteogenesis cases treated with the RED System. 38
21403527 2011
542
Genetic basis of non syndromic hypodontia: a DNA investigation performed on three couples of monozygotic twins about PAX9 mutation. 38
21434731 2011
543
Non-syndromic oligodontia with a novel mutation of PAX9. 38
21098475 2011
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Case report of oligodontia: long term stability of orthognatic surgery and prosthetic rehabilitation. 38
21270740 2011
545
Prevalence and patterns of permanent tooth agenesis in Down syndrome and their association with craniofacial morphology. 38
21208078 2011
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Polymorphisms in CHDH gene and the risk of tooth agenesis. 38
21308979 2011
547
[Prosthodontic treatment of congenital tooth agenesis II. Clinical character of tooth agenesis]. 38
21575444 2011
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Msx1 mutations: how do they cause tooth agenesis? 38
21297014 2011
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Tooth agenesis: dento-skeletal characteristics in subjects with orthodontic treatment need. 38
21434730 2011
550
Eponym: Johanson-Blizzard syndrome. 38
20556422 2011
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A whole-genome scan in a large family with leukodystrophy and oligodontia reveals linkage to 10q22. 38
20721593 2011
552
Survey of congenitally missing teeth in orthodontic patients in Eastern Bavaria. 38
20660130 2011
553
The genetic basis of craniofacial and dental abnormalities. 38
21861247 2011
554
Oligodontia associated with osteopetrosis: a rare case report. 38
22041010 2011
555
Transcriptional regulation of MSX1 natural antisense transcript. 38
21625063 2011
556
Regulation of bmp4 expression in odontogenic mesenchyme: from simple to complex. 38
21546760 2011
557
A new hypo/oligodontia syndrome: Carvajal/Naxos syndrome secondary to desmoplakin-dominant mutations. 38
20940358 2011
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Side of dental anomalies and taurodontism as potential clinical markers for cleft subphenotypes. 38
20507240 2011
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Dental agenesis patterns in Crouzon syndrome. 38
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[Prosthodontic treatment of congenital tooth agenesis I. The classicfication, prevalence and etiology of congenital tooth agenesis]. 38
21418949 2011
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Tooth agenesis: newer concept. 38
22900446 2011
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Agenesis of permanent mandibular anterior teeth: a case report. 38
22041015 2011
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Tooth agenesis patterns in bilateral cleft lip/palate (BCLP) indicate possible common genetic pathways. 38
21093815 2010
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Case report: Early prosthetic treatment in children with ectodermal dysplasia. 38
21108923 2010
565
Maxillary canine-first premolar transposition in the permanent dentition: treatment considerations and a case report. 38
21322365 2010
566
A novel missense mutation in the ectodysplasin-A (EDA) gene underlies X-linked recessive nonsyndromic hypodontia. 38
21091672 2010
567
Studies with Wnt genes and nonsyndromic cleft lip and palate. 38
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The contribution of orthodontics to the prosthodontic treatment of ectodermal dysplasia: a long-term clinical report. 38
21037191 2010
569
Maxillary first molar agenesis and other dental anomalies. 38
20677947 2010
570
Orthodontic treatment of a congenitally missing maxillary lateral incisor. 38
21029334 2010
571
Mutational analysis of MSX1 and PAX9 genes in Portuguese families with maxillary lateral incisor agenesis. 38
20660504 2010
572
Psoriatic triad in a patient presenting with oligodontia. 38
21273720 2010
573
Transcriptional activity analysis of promoter region of human PAX9 gene under dexamethasone, retinoic acid, and ergocalciferol treatment in MCF-7 and MDPC23. 38
20941745 2010
574
Non-syndromic hypodontia in an Iranian orthodontic population. 38
20881340 2010
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Non-syndromic oligodontia: a case report. 38
21089027 2010
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Frequency and characteristics of tooth agenesis among an orthodontic patient population. 38
20383097 2010
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X-linked and autosomal recessive Hypohidrotic Ectodermal Dysplasia: genotypic-dental phenotypic findings. 38
20236127 2010
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Transcriptional analysis of the human PAX9 promoter. 38
21085804 2010
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The role of complete overdentures in esthetic rehabilitation of the adolescent oligodontia patient. A case report. 38
20690948 2010
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Mutations in the PAX9 gene in sporadic oligodontia. 38
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COMMENTARY. The role of complete overdentures in esthetic rehabilitation of the adolescent oligodontia patient. A case report. 38
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An epidemiological study of dental agenesis in a primary health area in Spain: estimated prevalence and associated factors. 38
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Nevus comedonicus syndrome--nevus comedonicus associated with ipsilateral polysyndactyly and bilateral oligodontia. 38
20653857 2010
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[Correlation between the phenotype and genotype of tooth agenesis patients by tooth agenesis code]. 38
20602873 2010
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Prevalence of hypodontia in orthodontic patients in Brasilia, Brazil. 38
19837747 2010
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Agenesis of maxillary lateral incisors and associated dental anomalies. 38
20685523 2010
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Patterns of tooth agenesis in patients with Down syndrome in relation to hypothyroidism and congenital heart disease: an aid for treatment planning. 38
20451772 2010
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Missense mutation of the EDA gene in a Jordanian family with X-linked hypohidrotic ectodermal dysplasia: phenotypic appearance and speech problems. 38
20486090 2010
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Increased occurrence of dental anomalies associated with infraocclusion of deciduous molars. 38
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[Isolated oligodontia: a case presentation and review of the literature]. 38
21250401 2010
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Role of genes in oro-dental diseases. 38
20657100 2010
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Genetic interactions between Pax9 and Msx1 regulate lip development and several stages of tooth morphogenesis. 38
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[Msh homebox-1 polymorphisms and susceptibility to 198 sporadic tooth agenesis: a case-control study]. 38
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Non-syndromic oligodontia in permanent dentition of monozygotic twins: report of a rare case. 38
20228990 2010
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A treatment planning classification for oligodontia. 38
20305845 2010
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Implant treatment in patients with severe hypodontia: a retrospective evaluation. 38
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Genome-wide association study reveals multiple loci associated with primary tooth development during infancy. 38
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Tooth agenesis in patients referred to an Irish tertiary care clinic for the developmental dental disorders. 38
20337142 2010
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Tooth agenesis patterns in bilateral cleft lip and palate. 38
20156264 2010
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Dental abnormalities associated with X-linked hypohidrotic ectodermal dysplasia in dogs. 38
20078794 2010
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Functional aspects of treatment with implant-supported single crowns: a quality control study in subjects with tooth agenesis. 38
19845708 2010
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Ectodermal dysplasia-like syndrome with mental retardation due to contiguous gene deletion: further clinical and molecular delineation of del(2q32) syndrome. 38
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Functional analysis of Ectodysplasin-A mutations causing selective tooth agenesis. 38
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[Clinical and radiographic association between tooth agenesis and systemic pathology on a group of children from U.O.C. of paediatric dentistry of Sapienza University, Rome]. 38
20476664 2010
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Oral health-related quality of life of children with oligodontia. 38
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Oligodontia ectodermal dysplasia--on signs, symptoms, genetics, and outcomes of dental treatment. 38
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[Agenesis in permanent dentition]. 38
20379669 2009
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Studies of palatine rugae and interferon regulatory factor 6 variations in a group of families with sporadic hypodontia. 38
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[Mutation analysis of the eda-A1 gene for hypohidrotic ectodermal dysplasia and construction of recombined eukaryotic expression vector]. 38
20077893 2009
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Pseudoaminopterin syndrome: clinical report with new characteristics. 38
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Tooth dimensions in hypodontia with a known PAX9 mutation. 9
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Developmental disturbances associated with agenesis of the permanent maxillary lateral incisor. 38
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Steatocystoma multiplex, oligodontia and partial persistent primary dentition associated with a novel keratin 17 mutation. 38
19659471 2009
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Agenesis of a mandibular canine: a case report. 38
20486101 2009
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[Hypodontia: therapeutic strategy elaborated from 30 cases]. 38
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Treatment planning and surgical considerations in implant therapy for patients with agenesis, oligodontia, and ectodermal dysplasia: review and case presentation. 38
19835745 2009
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Polymorphism in the Msx1 gene associated with hypodontia in a Brazilian family. 9
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A longitudinal cephalometric study from age 5 to 18 years on individuals with complete bilateral cleft lip and palate. 38
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Genetics and human malformations. 38
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Molecular aspects of hypohidrotic ectodermal dysplasia. 38
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Long-term adverse effects of hematopoietic stem cell transplantation on dental development in children. 38
19139926 2009
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Recurrent mutations in functionally-related EDA and EDAR genes underlie X-linked isolated hypodontia and autosomal recessive hypohidrotic ectodermal dysplasia. 9
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From ectodermal dysplasia to selective tooth agenesis. 38
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Failures and complications in patients with birth defects restored with fixed dental prostheses and single crowns on teeth and/or implants. 38
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Cumulative costs for the prosthetic reconstructions and maintenance in young adult patients with birth defects affecting the formation of teeth. 38
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Autotransplantation of impacted teeth: a report of 3 cases and review of the literature. 38
19626234 2009
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Professional and patient-based evaluation of oral rehabilitation in patients with tooth agenesis. 38
19515060 2009
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Increased occurrence of dental anomalies associated with second-premolar agenesis. 38
19413376 2009
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Phylloid hypomelanosis and mosaic partial trisomy 13: two cases that provide further evidence of a distinct clinicogenetic entity. 38
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Morphological abnormalities in children with thyroidal congenital hypothyroidism. 38
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Dental implants in patients with ectodermal dysplasia and tooth agenesis: a critical review of the literature. 38
19548409 2009
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Agenesis of permanent teeth in 8138 Danish schoolchildren: prevalence and intra-oral distribution according to gender. 38
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Two novel mutations in the ED1 gene in Japanese families with X-linked hypohidrotic ectodermal dysplasia. 9
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Oligodontia is caused by mutation in LTBP3, the gene encoding latent TGF-beta binding protein 3. 38
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[A description of a population with severe oligodontia]. 38
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Oral rehabilitation for a patient with oligodontia and maxillary hypoplasia. 38
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Congenital oligodontia of the deciduous teeth and anodontia of the permanent teeth in a cat. 38
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[Anhidrotic ectodermal dysplasia. Rehabilitation]. 38
19155030 2009
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AXIN2 and CDH1 polymorphisms, tooth agenesis, and oral clefts. 38
18683894 2009
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[Patterns of tooth agenesis. A numerical code for describing dental agenesis]. 38
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Transforming growth factor-alfa gene (TGFA), human tooth agenesis, and evidence of segmental uniparental isodisomy. 38
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Defining subphenotypes for tooth agenesis: does side matter? 38
20297711 2009
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Consequences of X-linked hypohidrotic ectodermal dysplasia for the human jaw bone. 38
19828977 2009
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Craniodentofacial manifestations in Hallermann-Streiff syndrome. 38
19241797 2009
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Hypocalcified type of amelogenesis imperfecta in a large family: clinical, radiographic, and histological findings, associated dento-facial anomalies, and resulting treatment load. 38
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Axis inhibition protein 2 (AXIN2) polymorphisms and tooth agenesis. 38
18790474 2009
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Dental agenesis: genetic and clinical perspectives. 9
18771513 2009
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Christ Siemens Touraine syndrome: a case report. 38
19134218 2009
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Implant-prosthetic partial-arch restoration in a patient with ectodermal dysplasia characterized by oligodontia and localized bone deficiency: a case report. 38
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Msx1 expression regulation by its own antisense RNA: consequence on tooth development and bone regeneration. 38
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Identification and functional analysis of two novel PAX9 mutations. 38
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Dental arch dimensions in oligodontia patients. 38
19061803 2008
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X-linked hypohidrotic ectodermal dysplasia: a ten-year case report and clinical considerations. 38
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Oculofaciocardiodental syndrome: report of a rare case. 38
19093058 2008
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Tooth abnormalities and soft tissue alterations in patients with G/BBB syndrome. 38
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Polyneuropathy, scoliosis, tall stature, and oligodontia represent novel features of the interstitial 6p deletion phenotype. 38
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[Clinical examination of children with tooth aplasia. Correlations between dental symptoms and the whole organism]. 38
19039920 2008
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Hypohidrotic ectodermal dysplasia. 38
19061621 2008
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Mutations in the EDA gene are responsible for X-linked hypohidrotic ectodermal dysplasia and hypodontia in Chinese kindreds. 9
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Impacted primary tooth and tooth agenesis: a case report of monozygotic twins. 38
19212538 2008
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Studies of dental anomalies in a large group of school children. 38
18490001 2008
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Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts. 38
18978678 2008
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Dental management of a patient with oculo-facio-cardio-dental syndrome. 38
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Evidence of linkage disequilibrium between polymorphisms at the IRF6 locus and isolate tooth agenesis, in a Turkish population. 38
18452891 2008
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Tooth abnormalities and soft tissue changes in patients with velocardiofacial syndrome. 38
18554940 2008
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The genetic basis of inherited anomalies of the teeth. Part 1: clinical and molecular aspects of non-syndromic dental disorders. 38
18499550 2008
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Dental anomalies as part of the cleft spectrum. 38
18616370 2008
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Johanson-Blizzard syndrome: report of a novel mutation and severe liver involvement. 38
18553553 2008
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Tooth agenesis: from molecular genetics to molecular dentistry. 38
18573979 2008
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Non-syndromic tooth agenesis in two Chinese families associated with novel missense mutations in the TNF domain of EDA (ectodysplasin A). 38
18545687 2008
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Can persistence of primary molars be predicted in subjects with multiple tooth agenesis? 38
18540013 2008
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A genome wide linkage scan for cleft lip and palate and dental anomalies. 38
18442096 2008
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An orthopantomographic study of hypodontia in permanent teeth of Japanese pediatric patients. 38
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Implant failure in young children with ectodermal dysplasia: a retrospective evaluation of use and outcome of dental implant treatment in children in Sweden. 38
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Assessing the proposed association between tooth agenesis and taurodontism in 975 paediatric subjects. 38
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PAX9 polymorphisms and susceptibility to sporadic tooth agenesis: a case-control study in southeast China. 38
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A new autosomal recessive syndrome of ocular colobomas, ichthyosis, brain malformations and endocrine abnormalities in an inbred Emirati family. 38
18271001 2008
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Familial non-syndromic cleft lip and palate--analysis of the IRF6 gene and clinical phenotypes. 9
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Treatment of a patient with oligodontia: a case report. 38
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Dental implants in the management of nonsyndromal oligodontia. 38
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Use of dental implants in the management of syndromal oligodontia. 38
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Genotype-phenotype correlation in 21 patients with Wolf-Hirschhorn syndrome using high resolution array comparative genome hybridisation (CGH). 38
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Treatment with removable prosthesis in hypohidrotic ectodermal dysplasia. A clinical case. 38
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[Establishment of electronic medical record of patients with tooth agenesis]. 38
18683739 2008
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When should we extract deciduous teeth and place implants in young individuals with tooth agenesis? 38
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Tooth agenesis in a family and homozygous PAX9 mutation in exon 3: a case report. 38
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A novel missense mutation in the EDA gene associated with X-linked recessive isolated hypodontia. 9
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Multidisciplinary Management of Oligodontia. 38
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Progressive symmetric erythro-keratosis associated with oligodontia, severe caries, disturbed hair growth and ectopic nail: a new syndrome? 38
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[Clinical analysis of simple hypodontia]. 38
18476552 2007
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Biomechanical aspects of external root resorption in orthodontic therapy. 38
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Occipital atretic cephalocele, striking facial anomalies, and large feet in three siblings of a consanguineous union. 38
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Treatment of oligodontia with endo-osseous fixtures: experience in eight consecutive patients at the end of dental growth. 38
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Genes affecting tooth morphogenesis. 38
17973693 2007
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Association between polymorphism in the promoter region (G/C-915) of PAX9 gene and third molar agenesis. 9
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Cranial suture biology and dental development: genetic and clinical perspectives. 9
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Quest for the cause of oligodontia in Suncus murinus (Soricomorpha, Soricidae): Morphological re-examination. 38
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Genes affecting tooth morphogenesis. 38
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Familial human hypodontia--is it all in the genes? 38
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Derivation of a mouse model for conditional inactivation of Pax9. 38
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The role of MSX1 in tooth agenesis in Iranians. 38
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Patterns of missing teeth in a population of oligodontia patients. 38
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Treatment of severe hypodontia-oligodontia--an interdisciplinary concept. 38
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Oligodontia and associated characteristics: assessment in view of prosthodontic rehabilitation. 38
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Oligodontia in the primary dentition: report of a case. 38
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A critical evaluation of meta-analyses in orthodontics. 38
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An analysis of peripheral giant cell granuloma associated with dental implant treatment. 38
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Transitional implants in a patient with Williams-Beuren syndrome: a four-year follow-up. 38
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Developmental biology and genetics of dental malformations. 38
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Oligodontia in pseudoxanthoma elasticum. 38
17331755 2007
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Prevalence and distribution of dental anomalies in orthodontic patients. 38
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Craniofacial growth and functional change in oligodontia with ectodermal dysplasia: a case report. 38
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[Msx1 and its influence on craniofacial growth]. 38
17571531 2007
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Interferon regulatory factor 6 (IRF6) and fibroblast growth factor receptor 1 (FGFR1) contribute to human tooth agenesis. 38
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Abnormal dentin structure in two novel gene mutations [COL1A1, Arg134Cys] and [ADAMTS2, Trp795-to-ter] causing rare type I collagen disorders. 38
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[Research advances in tooth agenesis]. 38
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[Preprosthesis surgery: a case of oligodontia]. 38
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Esthetic and functional rehabilitation of a patient with nonsyndromic oligodontia: a case report from China. 38
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Idiopathic oligodontia in primary dentition: case report and review of literature. 38
18274474 2007
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Chondroectodermal dysplasia (Ellis van Creveld syndrome): a report of three cases with review of literature. 38
17347543 2007
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Oral findings in patients with Apert syndrome. 38
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Craniofacial and dental phenotype of Smith-Magenis syndrome. 38
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[Genetic studies of a Chilean family with three different dental anomalies]. 38
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Low frequency of AXIN2 mutations and high frequency of MUTYH mutations in patients with multiple polyposis. 38
16941501 2006
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Coffin-Lowry syndrome: findings and dental treatment. 38
17249444 2006
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Signs and symptoms from ectodermal organs in young Swedish individuals with oligodontia. 38
16879328 2006
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Functional consequences of interactions between Pax9 and Msx1 genes in normal and abnormal tooth development. 38
16651263 2006
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Prevalence of hypodontia and hyperdontia in paedodontic and orthodontic patients in Budapest. 38
16800362 2006
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MSX1 and orofacial clefting with and without tooth agenesis. 38
16723652 2006
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Prevalence of dental anomalies, ectopic eruption and associated oral malformations in subjects with Treacher Collins syndrome. 38
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A numeric code for identifying patterns of human tooth agenesis: a new approach. 38
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Growth analysis of a patient with ectodermal dysplasia treated with endosseous implants: 6-year follow-up. 38
16512883 2006
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Blepharo-cheilo-dontic (BCD) syndrome: case report. 38
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Ectrodactyly, ectodermal dysplasia, macular degeneration syndrome: a further contribution. 38
16970031 2006
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Axis inhibition protein 2 (AXIN2) polymorphisms may be a risk factor for selective tooth agenesis. 38
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Multiple developmental dental anomalies and hypermobility type Ehlers-Danlos syndrome. 9
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A novel missense mutation in MSX1 underlies autosomal recessive oligodontia with associated dental anomalies in Pakistani families. 38
16932841 2006
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A survey of hypodontia in Japanese orthodontic patients. 38
16443475 2006
739
Oligodontia in partial trisomy 9q syndrome. 38
17375539 2006
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Reduction of Pax9 gene dosage in an allelic series of mouse mutants causes hypodontia and oligodontia. 38
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[Gene mutation detection in a cleidocranial dysplasia family]. 38
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Acro-dermato-ungual-lacrimal-tooth (ADULT) syndrome: report of a child with phenotypic overlap with ulnar-mammary syndrome and a new mutation in TP63. 38
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Maxillary canine anomalies and tooth agenesis. 38
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[Oligodontia: treatment plan and therapy]. 38
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Mandibular lateral incisor-canine transposition associated with dental anomalies. 38
16015651 2005
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Skeletal Class III oligodontia patient treated with titanium screw anchorage and orthognathic surgery. 38
15953899 2005
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Oral rehabilitation with dental implants in oligodontia patients. 38
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Investigation of craniofacial morphology in patients with hypo- and oligodontia. 38
15959633 2005
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[Prevalence of congenitally missing teeth in Israeli recruits]. 38
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Maxillary distraction osteogenesis to treat maxillary hypoplasia: comparison of an internal and an external system. 38
15821694 2005
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[Recent advances in research of genes associated with human tooth agenesis and craniofacial malformation syndromes]. 38
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