MCID: TTH002
MIFTS: 60

Tooth Agenesis

Categories: Genetic diseases, Oral diseases, Rare diseases

Aliases & Classifications for Tooth Agenesis

MalaCards integrated aliases for Tooth Agenesis:

Name: Tooth Agenesis 12 36 6 15 17
Oligodontia 12 58 29 6
Selective Tooth Agenesis 12 58 6
Hypodontia 12 54 39
Tooth Agenesis, Selective 54
Familial Tooth Agenesis 12
Anodontia 43

Characteristics:

Orphanet epidemiological data:

58
oligodontia
Inheritance: Autosomal dominant,Autosomal recessive,X-linked recessive; Age of onset: Childhood; Age of death: normal life expectancy;

Classifications:

Orphanet: 58  
Rare odontological diseases


External Ids:

Disease Ontology 12 DOID:0050591
KEGG 36 H00625
ICD9CM 34 520.0
MeSH 43 D000848
SNOMED-CT 67 16958000
ICD10 32 K00.0
ICD10 via Orphanet 33 K00.0
Orphanet 58 ORPHA99798
SNOMED-CT via HPO 68 32337007 32958008
UMLS 71 C0399352

Summaries for Tooth Agenesis

KEGG : 36 Tooth agenesis, or hypodontia/origodontia, refers to the congenital absence of a few teeth without any systemic disorders. Tooth development is a complex process that involves interactions between the oral epithelium and an underlying mesenchyme. Perturbation of this process results in tooth agenesis. This disease could be inherited as either an autosomal dominant, autosomal recessive, or X-linked trait.

MalaCards based summary : Tooth Agenesis, also known as oligodontia, is related to witkop syndrome and ectodermal dysplasia 11a, hypohidrotic/hair/tooth type, autosomal dominant. An important gene associated with Tooth Agenesis is PAX9 (Paired Box 9), and among its related pathways/superpathways are Wnt signaling pathway and Nanog in Mammalian ESC Pluripotency. The drugs Amoxicillin and Ibuprofen have been mentioned in the context of this disorder. Affiliated tissues include bone, eye and salivary gland, and related phenotypes are microdontia and micrognathia

Disease Ontology : 12 A tooth disease characterized by failure to develop on or more missing teeth.

Wikipedia : 74 Hypodontia is defined as the developmental absence of one or more teeth excluding the third molars. It... more...

Related Diseases for Tooth Agenesis

Diseases related to Tooth Agenesis via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 355, show less)
# Related Disease Score Top Affiliating Genes
1 witkop syndrome 34.6 PAX9 MSX1 EDAR
2 ectodermal dysplasia 11a, hypohidrotic/hair/tooth type, autosomal dominant 32.7 PAX9 EDARADD EDAR EDA
3 ectodermal dysplasia 11b, hypohidrotic/hair/tooth type, autosomal recessive 32.7 PAX9 EDARADD EDAR EDA
4 ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant 32.7 PAX9 EDARADD EDAR EDA
5 ectodermal dysplasia 1, hypohidrotic, x-linked 32.6 EDARADD EDAR EDA
6 ectodermal dysplasia 31.9 WNT10A MSX1 EDARADD EDAR EDA DSP
7 cleft lip 31.8 TGFB3 TGFA SUMO1 PAX9 MSX1 IRF6
8 cleft lip/palate 31.8 TGFA MSX1 IRF6 FGFR1 CDH1 BMP4
9 ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive 31.7 WNT10A PAX9 EDARADD EDAR EDA
10 cleft palate, isolated 31.6 TGFB3 TGFA SUMO1 PAX9 MSX1 IRF6
11 anodontia 31.4 WNT10A PAX9 MSX1 EDARADD EDAR EDA
12 chromosome 2q35 duplication syndrome 31.4 MSX1 IRF6 FGFR1 BMP4
13 ankyloglossia with or without tooth anomalies 31.2 PAX9 MSX1 IRF6
14 cleft lip with or without cleft palate 31.2 TGFA MSX1 IRF6 CDH1 BMP4
15 van der woude syndrome 1 31.2 TGFB3 TGFA PAX9 MSX1 IRF6 FGFR1
16 orofacial cleft 31.2 WNT10A TGFB3 TGFA SUMO1 PAX9 MSX1
17 hyaline fibromatosis syndrome 31.0 WNT10B EDAR BMP4
18 tooth size 31.0 PAX9 MSX1 BMP4
19 hypohidrotic ectodermal dysplasia autosomal recessive 31.0 WNT10A EDARADD EDAR
20 cleft lip and alveolus 31.0 MSX1 IRF6
21 popliteal pterygium syndrome 30.9 TGFB3 MSX1 IRF6
22 schopf-schulz-passarge syndrome 30.9 WNT10A EDARADD EDAR
23 anhidrosis 30.9 EDARADD EDAR EDA
24 hypotrichosis 30.9 WNT10A EDARADD EDAR EDA
25 synostosis 30.8 FGFR1 BMP4 AXIN2
26 tooth agenesis, selective, 1 12.8
27 tooth agenesis, selective, 4 12.8
28 tooth agenesis, selective, 3 12.8
29 tooth agenesis, selective, x-linked, 1 12.8
30 tooth agenesis, selective, 7 12.6
31 tooth agenesis, selective, 8 12.6
32 tooth agenesis, selective, 9 12.6
33 cardiomyopathy, dilated, with woolly hair, keratoderma, and tooth agenesis 12.6
34 leukodystrophy, hypomyelinating, 8, with or without oligodontia and/or hypogonadotropic hypogonadism 12.6
35 malposition of teeth with or without hypodontia/oligodontia 12.5
36 tooth agenesis, selective, 5 12.5
37 hypodontia, x-linked 12.4
38 microdontia hypodontia short stature 12.4
39 leukomelanoderma, infantilism, mental retardation, hypodontia, hypotrichosis 12.3
40 tooth agenesis, selective, 2 12.3
41 brachymetapody-anodontia-hypotrichosis-albinoidism 12.3
42 epidermolysis bullosa simplex with anodontia/hypodontia 12.2
43 facial dysmorphism, selective tooth agenesis, and choroid calcification 12.2
44 cleft palate, deafness, and oligodontia 12.2
45 split-hand and split-foot with hypodontia 12.2
46 congenital heart disease ptosis hypodontia craniostosis 12.2
47 cleft lip palate oligodontia syndactyly pili torti 12.2
48 cleft palate stapes fixation oligodontia 12.2
49 leukodystrophy, hypomyelinating, 7, with or without oligodontia and/or hypogonadotropic hypogonadism 12.1
50 polr3-related leukodystrophy 12.1
51 oligodontia-colorectal cancer syndrome 12.1
52 adult syndrome 12.1
53 dermatoosteolysis, kirghizian type 11.9
54 deafness-oligodontia syndrome 11.9
55 zadik barak levin syndrome 11.9
56 ectodermal dysplasia 13, hair/tooth type 11.6
57 dental anomalies and short stature 11.6
58 late-onset localized junctional epidermolysis bullosa-intellectual disability syndrome 11.6
59 rapp-hodgkin syndrome 11.5
60 limb-mammary syndrome 11.5
61 ankyloblepharon-ectodermal defects-cleft lip/palate 11.5
62 mehta lewis patton syndrome 11.5
63 dentin dysplasia, type i 11.4
64 ectodermal dysplasia, trichoodontoonychial type 11.3
65 anauxetic dysplasia 1 11.3
66 ectodermal dysplasia 14, hair/tooth type with or without hypohidrosis 11.3
67 blepharocheilodontic syndrome 1 11.2
68 deafness, congenital, with onychodystrophy, autosomal dominant 11.2
69 ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome 11.2
70 blepharocheilodontic syndrome 2 11.2
71 osteoglophonic dysplasia 11.2
72 cranioectodermal dysplasia 1 11.2
73 lelis syndrome 11.2
74 even-plus syndrome 11.2
75 anauxetic dysplasia 2 11.2
76 trichorhinophalangeal syndrome, type ii 11.1
77 schimmelpenning-feuerstein-mims syndrome 11.1
78 trichorhinophalangeal syndrome, type i 11.1
79 uncombable hair, retinal pigmentary dystrophy, dental anomalies, and brachydactyly 11.1
80 johanson-blizzard syndrome 11.1
81 lipoid proteinosis of urbach and wiethe 11.1
82 ectodermal dysplasia with natal teeth, turnpenny type 11.1
83 acrofacial dysostosis, palagonia type 11.1
84 zechi-ceide syndrome 11.1
85 au-kline syndrome 11.1
86 acrofacial dysostosis, patagonia type 11.1
87 autosomal dominant deafness-onychodystrophy syndrome 11.1
88 stoll alembik finck syndrome 11.1
89 angel-shaped phalangoepiphyseal dysplasia 11.0
90 lacrimoauriculodentodigital syndrome 11.0
91 axenfeld-rieger syndrome, type 1 11.0
92 weyers acrofacial dysostosis 11.0
93 amelogenesis imperfecta, type ig 11.0
94 cerebellar ataxia and ectodermal dysplasia 11.0
95 cleft lip/palate-ectodermal dysplasia syndrome 11.0
96 faciocardiorenal syndrome 11.0
97 pilodental dysplasia with refractive errors 11.0
98 wiedemann-rautenstrauch syndrome 11.0
99 short syndrome 11.0
100 ectodermal dysplasia and immunodeficiency 1 11.0
101 immunodeficiency 33 11.0
102 arthrogryposis, ectodermal dysplasia, cleft lip/palate, and developmental delay 11.0
103 nicolaides-baraitser syndrome 11.0
104 ectodermal dysplasia 8, hair/tooth/nail type 11.0
105 ichthyosis, leukocyte vacuoles, alopecia, and sclerosing cholangitis 11.0
106 alopecia, neurologic defects, and endocrinopathy syndrome 11.0
107 fontaine progeroid syndrome 11.0
108 epileptic encephalopathy, early infantile, 25, with amelogenesis imperfecta 11.0
109 ectodermal dysplasia 12, hypohidrotic/hair/tooth/nail type 11.0
110 charlie m syndrome 11.0
111 odonto onycho dysplasia with alopecia 11.0
112 pinheiro freire-maia miranda syndrome 11.0
113 ectodermal dysplasia 10b 10.8 PAX9 EDARADD EDAR EDA
114 physical disorder 10.8 TGFB3 PAX9 MSX1 IRF6 BMP4
115 syngnathia 10.8 MSX1 IRF6 BMP4
116 pompholyx 10.8 EDARADD EDAR EDA
117 synovial chondromatosis 10.8 TGFB3 FGFR1 BMP4
118 sweat gland disease 10.8 EDARADD EDAR EDA
119 basal cell carcinoma 10.8 WNT10B WNT10A CDH1 BMP4 AXIN2
120 norrie disease 10.8 WNT10B WNT10A GREM2
121 odontochondrodysplasia 10.7 TGFB3 MSX1 FGFR1 BMP4
122 arrhythmogenic right ventricular dysplasia, familial, 4 10.7 TGFB3 DSP
123 arrhythmogenic right ventricular dysplasia, familial, 3 10.7 TGFB3 DSP
124 chromosome 10q23 deletion syndrome 10.7 MSX1 BMP4
125 lymphoid interstitial pneumonia 10.7 PAX9 MSX1 IRF6
126 arrhythmogenic right ventricular dysplasia, familial, 6 10.7 TGFB3 DSP
127 orofacial cleft 10 10.7 SUMO1 IRF6
128 orofacial cleft 4 10.7 WNT10B SUMO1
129 familial isolated arrhythmogenic ventricular dysplasia, left dominant form 10.7 TGFB3 DSP
130 familial isolated arrhythmogenic ventricular dysplasia, biventricular form 10.7 TGFB3 DSP
131 neural tube defects 10.7 TGFB3 PAX9 MSX1 LRP6 BMP4
132 familial isolated arrhythmogenic ventricular dysplasia, right dominant form 10.7 TGFB3 DSP
133 isolated cleft lip 10.7 MSX1 IRF6
134 atrophic rhinitis 10.6 EDARADD EDA
135 arrhythmogenic right ventricular dysplasia, familial, 8 10.6 TGFB3 DSP
136 fibular aplasia or hypoplasia, femoral bowing and poly-, syn-, and oligodactyly 10.6 WNT10A EDARADD
137 exudative vitreoretinopathy 10.6 WNT10B WNT10A LRP6
138 charge syndrome 10.5 MSX1 FGFR1 BMP4
139 arrhythmogenic right ventricular dysplasia, familial, 5 10.5 TGFB3 DSP
140 arrhythmogenic right ventricular dysplasia, familial, 13 10.4 TGFB3 DSP
141 hypogonadotropic hypogonadism 10.3
142 hypogonadism 10.3
143 gapo syndrome 10.3
144 ataxia and polyneuropathy, adult-onset 10.3
145 arrhythmogenic right ventricular dysplasia, familial, 2 10.2 TGFB3 DSP
146 hair whorl 10.2
147 down syndrome 10.2
148 hidrotic ectodermal dysplasia 2 10.2
149 split-hand/foot malformation 1 10.2
150 leukodystrophy 10.2
151 keratosis 10.2
152 taurodontism 10.2
153 nail disorder, nonsyndromic congenital, 9 10.1
154 ankylosis 10.1
155 craniosynostosis 10.1
156 isolated split hand-split foot malformation 10.1
157 colorectal cancer 10.1
158 odontoonychodermal dysplasia 10.1
159 isolated pierre robin sequence 10.1
160 cherubism 10.1
161 treacher collins syndrome 1 10.1
162 wolf-hirschhorn syndrome 10.1
163 chromosome 4p deletion 10.1
164 epidermolysis bullosa, late-onset localized junctional, with mental retardation 10.0
165 nephronophthisis 1 10.0
166 rothmund-thomson syndrome, type 2 10.0
167 patau syndrome 10.0
168 diarrhea 10.0
169 epidermolysis bullosa simplex 10.0
170 waardenburg's syndrome 10.0
171 periodontosis 10.0
172 medullary sponge kidney 10.0
173 sotos syndrome 1 10.0
174 ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 1 10.0
175 hemifacial microsomia 10.0
176 strabismus 10.0
177 fraser syndrome 1 10.0
178 autosomal recessive disease 10.0
179 dental caries 10.0
180 learning disability 10.0
181 mechanical strabismus 10.0
182 cryptophthalmos 10.0
183 ovarian cancer 10.0
184 teeth, supernumerary 10.0
185 incontinentia pigmenti 10.0
186 brittle bone disorder 10.0
187 root resorption 10.0
188 axenfeld-rieger syndrome 10.0
189 dentinogenesis imperfecta 10.0
190 achondroplasia 9.9
191 chorea, benign hereditary 9.9
192 floating-harbor syndrome 9.9
193 hypercholesterolemia, familial, 1 9.9
194 hypertelorism 9.9
195 keratitis, hereditary 9.9
196 macroglossia 9.9
197 microcephaly, autosomal dominant 9.9
198 otitis media 9.9
199 steatocystoma multiplex 9.9
200 anodontia of permanent dentition 9.9
201 ellis-van creveld syndrome 9.9
202 metachromatic leukodystrophy 9.9
203 microcephaly 1, primary, autosomal recessive 9.9
204 pseudoxanthoma elasticum 9.9
205 tibial hemimelia 9.9
206 focal dermal hypoplasia 9.9
207 orthostatic intolerance 9.9
208 chorea, childhood-onset, with psychomotor retardation 9.9
209 nevus comedonicus 9.9
210 seckel syndrome 9.9
211 mucositis 9.9
212 familial woolly hair syndrome 9.9
213 geleophysic dysplasia 9.9
214 suppression amblyopia 9.9
215 amblyopia 9.9
216 interstitial nephritis 9.9
217 juvenile glaucoma 9.9
218 polycystic ovary syndrome 9.9
219 choreatic disease 9.9
220 dilated cardiomyopathy 9.9
221 osteopetrosis 9.9
222 polyneuropathy 9.9
223 thrombocytopenia 9.9
224 hyperostosis 9.9
225 syringoma 9.9
226 focal epilepsy 9.9
227 corneal dystrophy 9.9
228 dermatitis 9.9
229 syphilis 9.9
230 pustulosis of palm and sole 9.9
231 mitral valve disease 9.9
232 psoriasis 9.9
233 congenital syphilis 9.9
234 nkx2-1-related disorders 9.9
235 48,xyyy 9.9
236 chromosome 9q duplication 9.9
237 dwarfism 9.9
238 pachygyria 9.9
239 hemimelia 9.9
240 temporomandibular joint anomaly 9.9
241 acanthosis nigricans 9.9
242 aniridia 1 9.9
243 book syndrome 9.9
244 alagille syndrome 1 9.9
245 coloboma of macula 9.9
246 dupuytren contracture 9.9
247 ear malformation 9.9
248 spondyloepiphyseal dysplasia with congenital joint dislocations 9.9
249 hypotrichosis 4 9.9
250 ige responsiveness, atopic 9.9
251 actinic prurigo 9.9
252 smith-magenis syndrome 9.9
253 teeth present at birth 9.9
254 telecanthus 9.9
255 renal hypodysplasia/aplasia 1 9.9
256 uvula, bifid 9.9
257 vertical talus, congenital 9.9
258 wolff-parkinson-white syndrome 9.9
259 yunis-varon syndrome 9.9
260 cryptorchidism, unilateral or bilateral 9.9
261 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 9.9
262 papillon-lefevre syndrome 9.9
263 neu-laxova syndrome 1 9.9
264 teeth, congenital absence of, with taurodontia and sparse hair 9.9
265 teeth, fused 9.9
266 yemenite deaf-blind hypopigmentation syndrome 9.9
267 langerhans cell histiocytosis 9.9
268 split-hand/foot malformation 4 9.9
269 hurler syndrome 9.9
270 choanal atresia, posterior 9.9
271 leukodystrophy, hypomyelinating, 5 9.9
272 intraocular pressure quantitative trait locus 9.9
273 glass syndrome 9.9
274 fanconi renotubular syndrome 2 9.9
275 alacrima, achalasia, and mental retardation syndrome 9.9
276 leukoencephalopathy with ataxia 9.9
277 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.9
278 fibroma 9.9
279 scoliosis 9.9
280 ptosis 9.9
281 hypomyelinating leukodystrophy 9.9
282 split hand-foot malformation 9.9
283 sensorineural hearing loss 9.9
284 fanconi syndrome 9.9
285 microcephaly 9.9
286 chronic apical periodontitis 9.9
287 heart disease 9.9
288 lacrimal duct obstruction 9.9
289 dysostosis 9.9
290 gingivitis 9.9
291 palmoplantar keratosis 9.9
292 histiocytosis 9.9
293 epidermolysis bullosa dystrophica 9.9
294 peripheral nervous system disease 9.9
295 situs inversus 9.9
296 periapical periodontitis 9.9
297 cataract 9.9
298 neuropathy 9.9
299 exophthalmos 9.9
300 clcn2-related leukoencephalopathy 9.9
301 pnpla6-related disorders 9.9
302 sickle cell disease 9.9
303 tp63-related disorders 9.9
304 cleft palate x-linked 9.9
305 erythrokeratoderma ''en cocardes'' 9.9
306 gigantism 9.9
307 hyperacusis 9.9
308 metatarsus adductus 9.9
309 odontoma 9.9
310 pili torti 9.9
311 encephalopathy 9.9
312 hypotonia 9.9
313 tremor 9.9
314 facial cleft 9.9
315 rare genetic skin disease 9.9
316 overgrowth syndrome 9.9
317 eec syndrome and related disorders 9.9
318 apert syndrome 9.9
319 amelogenesis imperfecta, type ia 9.9
320 cleidocranial dysplasia 9.9
321 crouzon syndrome 9.9
322 velocardiofacial syndrome 9.9
323 immune deficiency disease 9.9
324 3-methylglutaconic aciduria, type iii 9.9
325 pierre robin syndrome 9.9
326 microphthalmia, syndromic 2 9.9
327 orofaciodigital syndrome i 9.9
328 axenfeld-rieger syndrome, type 3 9.9
329 branchiootic syndrome 1 9.9
330 cardiomyopathy, dilated, with woolly hair and keratoderma 9.9
331 deafness, autosomal recessive 9.9
332 orofacial cleft 5 9.9
333 choreoathetosis and congenital hypothyroidism with or without pulmonary dysfunction 9.9
334 chromosome 14q11-q22 deletion syndrome 9.9
335 gastric cancer 9.9
336 deafness, autosomal recessive 98 9.9
337 myelomeningocele 9.9
338 syndromic microphthalmia 9.9
339 microphthalmia 9.9
340 fissured tongue 9.9
341 hypothyroidism 9.9
342 amelogenesis imperfecta 9.9
343 hemangioma 9.9
344 epidermolysis bullosa 9.9
345 junctional epidermolysis bullosa 9.9
346 dentin dysplasia 9.9
347 anthrax disease 9.9
348 periodontitis 9.9
349 alopecia 9.9
350 47,xyy 9.9
351 cleidocranial dysplasia spectrum disorder 9.9
352 irf6-related disorders 9.9
353 chromosomal triplication 9.9
354 ovarian epithelial cancer 9.9
355 regional odontodysplasia 9.9

Graphical network of the top 20 diseases related to Tooth Agenesis:



Diseases related to Tooth Agenesis

Symptoms & Phenotypes for Tooth Agenesis

Human phenotypes related to Tooth Agenesis:

58 31 (showing 6, show less)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 microdontia 58 31 hallmark (90%) Very frequent (99-80%) HP:0000691
2 micrognathia 58 31 hallmark (90%) Very frequent (99-80%) HP:0000347
3 hypoplasia of the maxilla 58 31 hallmark (90%) Very frequent (99-80%) HP:0000327
4 oligodontia 58 31 hallmark (90%) Very frequent (99-80%) HP:0000677
5 abnormality of the face 58 Very frequent (99-80%)
6 abnormality of dental morphology 58 Very frequent (99-80%)

GenomeRNAi Phenotypes related to Tooth Agenesis according to GeneCards Suite gene sharing:

26 (showing 30, show less)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-110 9.77 IRF6
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-119 9.77 TGFA
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-126 9.77 FGFR1
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.77 FGFR1
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-152 9.77 TGFA
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-169 9.77 TGFA
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-176 9.77 IRF6
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-179 9.77 TGFA
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-40 9.77 FGFR1
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-61 9.77 IRF6
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-73 9.77 FGFR1
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-85 9.77 TGFA
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-87 9.77 TGFA
14 Increased shRNA abundance (Z-score > 2) GR00366-A-102 9.64 LRP6
15 Increased shRNA abundance (Z-score > 2) GR00366-A-104 9.64 WNT10B
16 Increased shRNA abundance (Z-score > 2) GR00366-A-117 9.64 AXIN2 LRP6 WNT10B
17 Increased shRNA abundance (Z-score > 2) GR00366-A-146 9.64 LRP6
18 Increased shRNA abundance (Z-score > 2) GR00366-A-153 9.64 LRP6 WNT10B
19 Increased shRNA abundance (Z-score > 2) GR00366-A-155 9.64 WNT10B
20 Increased shRNA abundance (Z-score > 2) GR00366-A-195 9.64 LRP6
21 Increased shRNA abundance (Z-score > 2) GR00366-A-198 9.64 LRP6
22 Increased shRNA abundance (Z-score > 2) GR00366-A-211 9.64 LRP6
23 Increased shRNA abundance (Z-score > 2) GR00366-A-213 9.64 LRP6 WNT10B
24 Increased shRNA abundance (Z-score > 2) GR00366-A-23 9.64 AXIN2
25 Increased shRNA abundance (Z-score > 2) GR00366-A-34 9.64 WNT10B
26 Increased shRNA abundance (Z-score > 2) GR00366-A-36 9.64 AXIN2
27 Increased shRNA abundance (Z-score > 2) GR00366-A-49 9.64 LRP6
28 Increased shRNA abundance (Z-score > 2) GR00366-A-60 9.64 AXIN2
29 Increased shRNA abundance (Z-score > 2) GR00366-A-81 9.64 LRP6
30 Increased shRNA abundance (Z-score > 2) GR00366-A-88 9.64 AXIN2

MGI Mouse Phenotypes related to Tooth Agenesis:

45 (showing 16, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 10.41 AXIN2 BMP4 DSP EDAR EDARADD FGFR1
2 growth/size/body region MP:0005378 10.38 AXIN2 BMP4 CDH1 DSP EDAR EDARADD
3 digestive/alimentary MP:0005381 10.37 AXIN2 BMP4 CDH1 DSP EDAR FGFR1
4 cardiovascular system MP:0005385 10.3 AXIN2 BMP4 CDH1 DSP EDAR FGFR1
5 cellular MP:0005384 10.29 AXIN2 BMP4 CDH1 DSP EDAR FGFR1
6 endocrine/exocrine gland MP:0005379 10.24 AXIN2 BMP4 CDH1 EDAR EDARADD FGFR1
7 embryo MP:0005380 10.21 AXIN2 BMP4 CDH1 DSP FGFR1 IRF6
8 integument MP:0010771 10.21 AXIN2 BMP4 CDH1 DSP EDAR EDARADD
9 mortality/aging MP:0010768 10.21 AXIN2 BMP4 CDH1 DSP EDAR EDARADD
10 limbs/digits/tail MP:0005371 10.14 AXIN2 BMP4 EDAR EDARADD FGFR1 IRF6
11 hearing/vestibular/ear MP:0005377 10 BMP4 EDARADD FGFR1 IRF6 LRP6 MSX1
12 normal MP:0002873 9.91 AXIN2 BMP4 CDH1 FGFR1 LRP6 MSX1
13 muscle MP:0005369 9.87 BMP4 DSP FGFR1 MSX1 PAX9 TGFA
14 reproductive system MP:0005389 9.85 AXIN2 BMP4 CDH1 EDAR EDARADD FGFR1
15 skeleton MP:0005390 9.8 AXIN2 BMP4 EDAR EDARADD FGFR1 GREM2
16 vision/eye MP:0005391 9.32 AXIN2 BMP4 EDAR EDARADD FGFR1 GREM2

Drugs & Therapeutics for Tooth Agenesis

Drugs for Tooth Agenesis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 12, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
2
Ibuprofen Approved Phase 4 15687-27-1 3672
3 Acetaminophen, hydrocodone drug combination Phase 4
4 Pharmaceutical Solutions Phase 4
5
Cobalt Approved, Experimental 7440-48-4 104729
6
Salicylic acid Approved, Investigational, Vet_approved 69-72-7 338
7
Lithium carbonate Approved 554-13-2
8 Anesthetics
9 Anti-Bacterial Agents
10 Antibiotics, Antitubercular
11 Antidepressive Agents
12 Psychotropic Drugs

Interventional clinical trials:

(showing 38, show less)
# Name Status NCT ID Phase Drugs
1 The Effectiveness of the Cytoplast Technique in Preventing Bone Loss Around Immediate Implant Placement in the Esthetic Zone. A Randomized Clinical Trial. Completed NCT01628367 Phase 4 Medications
2 A Phase III, Randomized, Controlled Clinical Trial of Lateral Ridge Augmentation Using Autogenous Bone Blocks or Xenogenic Bone Block Grafts Loaded With Recombinant Human Bone Morphogenic Protein 2 Active, not recruiting NCT01541345 Phase 3 InductOs
3 Cephalometric Indicators of Biological Responsiveness to Orthodontic Treatment of Class II/I in Growing Patients Completed NCT00248014 Phase 2
4 Linkage and Identification of (a) Candidate Gene(s) for Tooth Disorders Unknown status NCT00026026
5 Frequency of Hypodontia After Chemotherapy in Childhood Cancer Survivors: A Cross Sectional Study Unknown status NCT03445026
6 Hypodontia and Ovarian Cancer - the Connection Between Dental Agenesis and Epithelial Cancers, Especially Ovarian Cancer. Unknown status NCT01470235
7 Evaluation of Retention of Metal Reinforced Polyamide Denture Base Compared to Conventional Heat Cured Acrylic Resin Denture Base in Complete Mandibular Denture Unknown status NCT03385746
8 Clinical and Radiological Outcomes Study on Astra Tech Osseospeed Tx Profile Implant Unknown status NCT01510470
9 Clinical Study on Zirconia Bridges Unknown status NCT01835834
10 A Single-centre Randomised Controlled Clinical Trial of Zirconia-based Versus Metal-based Adhesive Bridges for Replacing 2 Missing Teeth or Less in Adults. Unknown status NCT01347177
11 Immediate and Early Loading of Hydrothermally Treated, Hydroxyapatite-Coated Dental Implants:a Controlled Randomized Prospective Clinical Study Unknown status NCT02397044
12 The Effect of Platform-Matching Versus Platform-Switching Using Standard Internal Versus Tapered Internal Plus Dental Implants on Peri-implant Hard and Soft Tissue Healing Unknown status NCT02536716
13 Is a Primer Needed for Orthodontic Bonding? A Multi-centre RCT Unknown status NCT01782521
14 A Comparison of Zirconia CAD/CAM and Conventionally Fabricated Single Implant Abutments and Restorations in the Esthetic Zone: a Randomized Controlled Clinical Trial. Unknown status NCT01229995
15 Investigation of Chronic Inflammatory Processes in the Respiratory Tract and the Eyes of Male Individuals With X-linked Hypohidrotic Ectodermal Dysplasia Completed NCT01308333
16 Correlation Study Between Socio-economical Deprivation and Oral Health in in French Children of 9 Years of Age in 2017. A Nationwide Database Retrospective Observational Cohort Study Completed NCT03817437
17 A Pilot Study Investigating Oral Health Related Quality of Life Improvements in Removable Partial Denture Treatments for the Replacement of Missing Teeth Completed NCT01953991
18 Platform Switching vs Regular Platform Implants. One Year Results From a RCT Completed NCT02123420
19 A Comparative, Randomized, Prospective, Clinical Study to Evaluate the Facial Bone and Esthetic Outcome of Buccal Augmentation Bone Grafting Techniques in Early (Type 2) Implant Placement Completed NCT03302143
20 Orodental Manifestations of Rare Diseases Recruiting NCT02397824
21 Effect of Neurectomy of Nasopalatine Nerve on Sensation of Anterior Palate in Patient Undergoing Rehabilitation of Atrophic Anterior Maxillary Ridge With Dental Implant Recruiting NCT04153851
22 Evaluation Of Innovative 3D Printed Space Maintainer Versus Conventional One Recruiting NCT04221243
23 Comparison of Different Drilling Speed to Classify Bone Quality by Tactile Sensation on a Saw Bone Model Recruiting NCT03877419
24 Autotransplantation of Teeth With Advanced or Completed Root Development With Intraoperative Extra-corporal Apicoectomy Recruiting NCT04041518
25 A Prospective, Single-Centre, Post-Market Study to Evaluate the Use of Polyetheretherketone (PEEK) Full-Arch Implant-Supported Prostheses in the Edentulous Jaw Recruiting NCT03655990
26 Evaluation of the Efficacy of Clear Aligners in the Correction of Severe Dental Crowding Cases Combined With Premolar Extraction Versus Vestibular Fixed Orthodontic Appliances: A Randomized Clinical Controlled Trial Recruiting NCT03645356
27 Novel Use of 2-unit Cantilever Resin-bonded Bridges for Replacing Missing Molar Teeth - a Randomized Clinical Trial Recruiting NCT02239718
28 Retention and Durability of the Anterior Zirconia Wing Bridge Recruiting NCT04378140
29 Coordination of Rare Diseases at Sanford Recruiting NCT01793168
30 REFRAME RPD Post-Market Clinical Study Active, not recruiting NCT03198520
31 A Histomorphometric Analysis of New Bone Formation Following Sinus Augmentation Using Two Different Bone Graft Materials. A Pilot Study in Humans. Active, not recruiting NCT03059914
32 Extension Study of XLHED-Affected Male Subjects Treated With EDI200 in Protocol ECP-002 Active, not recruiting NCT01992289 EDI200
33 A Proof of Concept for All-ceramic Zirconia Resin Bonded Bridges for Canine, Premolar and Short Span Posterior Teeth Official Title: Enrolling by invitation NCT02793037
34 Evaluation of the Effect of Slopped Shoulder Implant Neck Versus Conventional Implant Neck Design on the Crestal Bone Level in the Maxilla: Randomized Clinical Trial (RCT) Not yet recruiting NCT03614442
35 No-preparation Resin Bonded Bridges for the Replacement of Single Missing Teeth Not yet recruiting NCT03029637
36 Clinical Assessment Of Inlay Retained Bridge Designs (Tub Shaped And Inlay Shaped) In Missing Posterior Teeth Cases. Not yet recruiting NCT03715842
37 Clinical Evaluation of Chairside Computer Assisted Design/Computer Assisted Machining (CAD/CAM) Lithium Disilicate Fixed Partial Dentures (FPD) Suspended NCT03036566
38 Observational, Case-Series Study Evaluation of Bone Width and Dental Implant Stability When Using the Densah Bur™ Bone Compaction Process to Prepare Dental Implant Sites Withdrawn NCT02502058

Search NIH Clinical Center for Tooth Agenesis

Cochrane evidence based reviews: anodontia

Genetic Tests for Tooth Agenesis

Genetic tests related to Tooth Agenesis:

# Genetic test Affiliating Genes
1 Oligodontia 29

Anatomical Context for Tooth Agenesis

MalaCards organs/tissues related to Tooth Agenesis:

40
Bone, Eye, Salivary Gland, Brain, Heart, Thyroid, Liver

Publications for Tooth Agenesis

Articles related to Tooth Agenesis:

(showing 1054, show less)
# Title Authors PMID Year
1
EDA gene mutations underlie non-syndromic oligodontia. 54 6 61
19278982 2009
2
A novel missense mutation in the paired domain of human PAX9 causes oligodontia. 6 54 61
17910065 2007
3
[Novel mutations of PAX9 gene in Chinese patients with oligodontia]. 61 6 54
16191360 2005
4
A novel missense mutation in the paired domain of PAX9 causes non-syndromic oligodontia. 61 54 6
14689302 2004
5
Novel mutation in the paired box sequence of PAX9 gene in a sporadic form of oligodontia. 54 6 61
12786960 2003
6
A novel mutation in human PAX9 causes molar oligodontia. 54 61 6
11827258 2002
7
Identification of a nonsense mutation in the PAX9 gene in molar oligodontia. 6 54 61
11781684 2001
8
Haploinsufficiency of MSX1: a mechanism for selective tooth agenesis. 61 54 6
9742121 1998
9
A human MSX1 homeodomain missense mutation causes selective tooth agenesis. 6 61 54
8696335 1996
10
Mutations in WNT10B Are Identified in Individuals with Oligodontia. 6 61
27321946 2016
11
Loss-of-Function Mutations in the WNT Co-receptor LRP6 Cause Autosomal-Dominant Oligodontia. 61 6
26387593 2015
12
WNT10A mutations account for ¼ of population-based isolated oligodontia and show phenotypic correlations. 61 6
24449199 2014
13
Mutations in WNT10A are frequently involved in oligodontia associated with minor signs of ectodermal dysplasia. 6 61
23401279 2013
14
Mutations in WNT10A are present in more than half of isolated hypodontia cases. 6 61
22581971 2012
15
Pathogenic mechanisms of tooth agenesis linked to paired domain mutations in human PAX9. 61 6
19429910 2009
16
WNT10A mutations are a frequent cause of a broad spectrum of ectodermal dysplasias with sex-biased manifestation pattern in heterozygotes. 61 6
19559398 2009
17
Novel EDA mutation resulting in X-linked non-syndromic hypodontia and the pattern of EDA-associated isolated tooth agenesis. 61 6
18657636 2008
18
A novel Gln358Glu mutation in ectodysplasin A associated with X-linked dominant incisor hypodontia. 54 6
17256800 2007
19
Molecular characterization of a novel PAX9 missense mutation causing posterior tooth agenesis. 6 61
16479262 2006
20
Novel MSX1 frameshift causes autosomal-dominant oligodontia. 61 6
16498076 2006
21
A novel mutation in PAX9 causes familial form of molar oligodontia. 6 61
16333316 2006
22
A novel missense mutation of the EDA gene in a Mongolian family with congenital hypodontia. 6 54
16583127 2006
23
Novel mutation of the initiation codon of PAX9 causes oligodontia. 6 61
15615874 2005
24
A novel MSX1 mutation in hypodontia. 6 61
15264286 2004
25
Functional analysis of a mutation in PAX9 associated with familial tooth agenesis in humans. 61 6
14607846 2004
26
A missense mutation in PAX9 in a family with distinct phenotype of oligodontia. 6 61
14571272 2003
27
Novel missense mutations and a 288-bp exonic insertion in PAX9 in families with autosomal dominant hypodontia. 6 54
12605438 2003
28
Haploinsufficiency of PAX9 is associated with autosomal dominant hypodontia. 6 54
11941488 2002
29
The role of MSX1 in human tooth agenesis. 61 6
12097313 2002
30
MSX1 mutation is associated with orofacial clefting and tooth agenesis in humans. 61 6
10742093 2000
31
Mutation of PAX9 is associated with oligodontia. 6 61
10615120 2000
32
WNT10A mutations also associated with agenesis of the maxillary permanent canines, a separate entity. 6
24311251 2014
33
WNT10A and isolated hypodontia. 6
21484994 2011
34
A 223-kb de novo deletion of PAX9 in a patient with oligodontia. 54 61
20485064 2010
35
[Analysis of clinical features and mutation associated with oligodontia]. 61 54
20077892 2009
36
Genetic basis of tooth agenesis. 61 54
19219933 2009
37
Mutations in the human homeobox MSX1 gene in the congenital lack of permanent teeth. 54 61
19346736 2009
38
Dento-craniofacial phenotypes and underlying molecular mechanisms in hypohidrotic ectodermal dysplasia (HED): a review. 61 54
19029074 2008
39
Deletion of PAX9 and oligodontia: a third family and review of the literature. 54 61
18445003 2008
40
Identification of a novel missense mutation of MSX1 gene in Chinese family with autosomal-dominant oligodontia. 61 54
18374898 2008
41
[A novel mutation of MSX1 gene in a Chinese pedigree with oligodontia]. 54 61
18788550 2008
42
Investigating the etiology of multiple tooth agenesis in three sisters with severe oligodontia. 54 61
18199077 2008
43
Identification of a novel mutation in the PAX9 gene in a family affected by oligodontia and other dental anomalies. 61 54
18028048 2007
44
A novel nonsense mutation in PAX9 is associated with marked variability in number of missing teeth. 54 61
17697174 2007
45
Seckel syndrome associated with oligodontia, microdontia, enamel hypoplasia, delayed eruption, and dentin dysmineralization: a new variant? 54 61
17032400 2006
46
Exclusion of coding region mutations in MSX1, PAX9 and AXIN2 in eight patients with severe oligodontia phenotype. 54 61
16918677 2006
47
Natural selection and molecular evolution in primate PAX9 gene, a major determinant of tooth development. 61 54
16585527 2006
48
A novel c.581C>T transition localized in a highly conserved homeobox sequence of MSX1: is it responsible for oligodontia? 54 61
16682758 2006
49
Association between PAX-9 promoter polymorphisms and hypodontia in humans. 54 61
16137495 2005
50
[Functional analysis of novel mutations in PAX9 associated with familial oligodontia]. 61 54
16086281 2005
51
Novel identification of a four-base-pair deletion mutation in PITX2 in a Rieger syndrome family. 61 54
14630904 2003
52
MSX1 gene is deleted in Wolf-Hirschhorn syndrome patients with oligodontia. 61 54
14630905 2003
53
The novel polymorphic variants within the paired box of the PAX9 gene are associated with selective tooth agenesis. 61 54
11374781 2001
54
Clinical, radiographic, and genetic evaluation of a novel form of autosomal-dominant oligodontia. 54 61
11005730 2000
55
[Palmoplantar epidermal atrophy with hypokeratosis, dys- and hypotrichosis, hypodontia, enamel and dentin hypoplasia, isolated cleft palate with cleft uvula, strabismus cryptorchism and other anomalies--an undescribed ecto-mesodermal dysplasia?]. 54 61
1677642 1991
56
Genodermatoses with teeth abnormalities. 61
32027427 2020
57
Microcephalic osteodysplastic primordial dwarfism type II: Additional nine patients with implications on phenotype and genotype correlation. 61
32267100 2020
58
Impacts of oligodontia on oral health-related quality of life reported by affected children and their parents. 61
31184709 2020
59
Novel TSPEAR mutations in non-syndromic oligodontia. 61
32112661 2020
60
The C-terminal region including the MH6 domain of Msx1 regulates skeletal development. 61
32192766 2020
61
Exploring the presence of dental anomalies as a consequence of treatment of malignancy: A case report. 61
32322476 2020
62
Co-morbidity of down syndrome with autism spectrum disorder: Dental implications. 61
32489813 2020
63
Developmental dental anomalies assessed by panoramic radiographs in a Greek orthodontic population sample. 61
31494863 2020
64
The Connective Tissue Disorder Associated with Recessive Variants in the SLC39A13 Zinc Transporter Gene (Spondylo-Dysplastic Ehlers-Danlos Syndrome Type 3): Insights from Four Novel Patients and Follow-Up on Two Original Cases. 61
32295219 2020
65
Novel EDAR mutation in tooth agenesis and variable associated features. 61
32325225 2020
66
Association between craniofacial morphological patterns and tooth agenesis-related genes. 61
32249341 2020
67
POLR3A variants in striatal involvement without diffuse hypomyelination. 61
31932101 2020
68
LEF1 haploinsufficiency causes ectodermal dysplasia. 61
32022899 2020
69
A variant of neonatal progeroid syndrome, or Wiedemann-Rautenstrauch syndrome, is associated with a nonsense variant in POLR3GL. 61
31695177 2020
70
Mutations in COL1A1/A2 and CREB3L1 are associated with oligodontia in osteogenesis imperfecta. 61
32234057 2020
71
Size and bridging of the sella turcica in Japanese orthodontic patients with tooth agenesis. 61
32232696 2020
72
Third molar agenesis: Prevalence and Association with agenesis of other teeth in a Turkish population. 61
32134041 2020
73
Number of teeth is associated with facial size in humans. 61
32019986 2020
74
Maxillary incisor root morphology in patients with nonsyndromic tooth agenesis: A controlled cross-sectional pilot study. 61
32005473 2020
75
Microcephalic osteodyplastic primordial dwarfism type II: case report with unique oral findings and a new mutation in the pericentrin gene. 61
31606423 2020
76
Aymé-Gripp Syndrome 61
32027476 2020
77
Association between MSX1 rs12532 polymorphism with nonsyndromic unilateral complete cleft lip and palate and tooth agenesis. 61
31568994 2020
78
Two novel mutations in MSX1 causing oligodontia. 61
31914153 2020
79
Orthodontic management of a non-syndromic patient with concomitant bimaxillary hypohyperdontia: a case report. 61
32215476 2020
80
Biallelic variants in POLR3GL cause endosteal hyperostosis and oligodontia. 61
31089205 2020
81
A novel mutation of MSX1 inherited from maternal mosaicism causes a severely affected child with nonsyndromic oligodontia. 61
31469409 2020
82
Some Cancer Chemotherapy (CH) Agents May Be Associated With Tooth Agenesis, Though CH Dose, Age of CH Exposure, and Dental Development at the Time of Treatment May Be Critical Determinants. 61
31843187 2019
83
Comparison of the Angulation of the Unerupted Mandibular Second Premolar in Turkish Population with Tooth Agenesis. 61
32110463 2019
84
EDA, EDAR, EDARADD and WNT10A allelic variants in patients with ectodermal derivative impairment in the Spanish population. 61
31796081 2019
85
Three rare disease diagnoses in one patient through exome sequencing. 61
31427378 2019
86
Prosthodontic Management of a Pediatric Patient with Christ-Siemens-Touraine Syndrome: A Case Report. 61
32440077 2019
87
Prosthetic rehabilitation with fixed prosthesis of a 5-year-old child with Hypohidrotic Ectodermal Dysplasia and Oligodontia: a case report. 61
31699141 2019
88
Novel PITX2 mutations identified in Axenfeld-Rieger syndrome and the pattern of PITX2-related tooth agenesis. 61
31529555 2019
89
Prevalence and patterns of tooth agenesis among malocclusion classes in a Japanese orthodontic population. 61
31548453 2019
90
Familial oligodontia and regional odontodysplasia associated with a PAX9 initiation codon mutation. 61
30809714 2019
91
Association between Maternal Smoking during Pregnancy and Missing Teeth in Adolescents. 61
31744054 2019
92
Deleterious Variants in WNT10A, EDAR, and EDA Causing Isolated and Syndromic Tooth Agenesis: A Structural Perspective from Molecular Dynamics Simulations. 61
31652981 2019
93
Autosomal-Recessive Mutations in MESD Cause Osteogenesis Imperfecta. 61
31564437 2019
94
Oral Rehabilitation of Hypodontia Patients Using an Endosseous Dental Implant: Functional and Aesthetic Results. 61
31618898 2019
95
Stage- and tissue-specific effect of cyclophosphamide during tooth development. 61
30715254 2019
96
Α de novo 3.8-Mb inversion affecting the EDA and XIST genes in a heterozygous female calf with generalized hypohidrotic ectodermal dysplasia. 61
31533624 2019
97
Oral Rehabilitation of a Child with Hypohidrotic Ectodermal Dysplasia. 61
31645258 2019
98
Oral and dental findings in emanuel syndrome. 61
30980693 2019
99
Prevalence and patterns of tooth agenesis in Angle class II division 2 malocclusion in Italy: A case-control study. 61
31300232 2019
100
Follow-Up of Non-Syndromic Oligodontia With Conservative Approach. 61
31033683 2019
101
The Era of the Genome and Dental Medicine. 61
31329043 2019
102
Tooth agenesis patterns in Japanese orthodontic patients with nonsyndromic oligodontia. 61
31375234 2019
103
BMP4 mutations in tooth agenesis and low bone mass. 61
31128441 2019
104
Tooth Agenesis in Patients with Complete Bilateral Cleft Lip and Palate. 61
31909016 2019
105
Tooth agenesis-related GLI2 and GLI3 genes may contribute to craniofacial skeletal morphology in humans. 61
31112935 2019
106
WNT10A mutations causing oligodontia. 61
31103801 2019
107
Phenotypic confirmation of oligodontia, colorectal polyposis and cancer in a family carrying an exon 7 nonsense variant in the AXIN2 gene. 61
30671715 2019
108
Oral Health-Related Quality of Life in Dutch Children Diagnosed with Oligodontia. A Cross-Sectional Study. 61
31277355 2019
109
Prevalence of WNT10A gene mutations in non-syndromic oligodontia. 61
30426266 2019
110
Early prosthodontic intervention on two three-year-old twin girls with ectodermal dysplasia. 61
31246091 2019
111
Concurrent manifestation of oligodontia and thrombocytopenia caused by a contiguous gene deletion in 12p13.2: A three-generation clinical report. 61
30950205 2019
112
Relationship between obesity and prevalence of dental anomalies: Does body mass index play a role? 61
31246082 2019
113
The Smith-Lemli-Opitz syndrome and dentofacial anomalies diagnostic: Case reports and literature review. 61
31005410 2019
114
Chromosomal imbalance in pigs showing a syndromic form of cleft palate. 61
31068123 2019
115
A Bibliometric Analysis of Cleft Lip and Palate-Related Publication Trends From 2000 to 2017. 61
30376727 2019
116
Using of modified rapid palate expander with miniscrews in a patient affected by ectodermic dysplasia. 61
31173044 2019
117
A novel inhibitor of nuclear factor kappa-B kinase subunit gamma mutation identified in an incontinentia pigmenti patient with syndromic tooth agenesis. 61
30913450 2019
118
Special-needs patients in pediatric dentistry: Progeroid syndrome. A case of dental management and oral rehabilitation. 61
31214300 2019
119
Experiences of daily life and oral rehabilitation in oligodontia - a qualitative study. 61
30646789 2019
120
Anatomical analysis of zygomatic bone in ectodermal dysplasia patients with oligodontia. 61
30793468 2019
121
Hypodontia, Oligodontia and Anodontia in West Virginia Appalachia. 61
31015306 2019
122
[Tooth agenesis]. 61
30982737 2019
123
Genetic analysis: Wnt and other pathways in nonsyndromic tooth agenesis. 61
29969831 2019
124
Hypohydrotic Ectodermal Dysplasia in an Indian Family. 61
30925967 2019
125
Non-syndromic cleft lip with or without palate susceptible loci is associated with tooth agenesis. 61
30578605 2019
126
Au-Kline Syndrome 61
30998304 2019
127
Interdisciplinary Approach to Treat Patients With Tooth Agenesis: A Case Report. 61
31490036 2019
128
Novel mutations identified in patients with tooth agenesis by whole-exome sequencing. 61
30417976 2019
129
Variants of the ectodysplasin A1 receptor gene underlying homozygous cases of autosomal recessive hypohidrotic ectodermal dysplasia. 61
30623979 2019
130
Oral sequelae and rehabilitation considerations for survivors of childhood cancer. 61
30850784 2019
131
Oculo-Facio-Cardio-Dental Syndrome: A Case Report about a Rare Pathological Condition. 61
30875852 2019
132
Patterns of congenitally missing teeth of non-syndromic and syndromic patients treated at a single-center over the past thirty years. 61
30496934 2019
133
[Detection and functional analysis of BMP2 gene mutation in patients with tooth agenesis]. 61
30773537 2019
134
Oro-dental phenotype in patients with RUNX2 duplication. 61
29852250 2019
135
Novel dental phenotype in non-syndromic Pierre Robin Sequence: A retrospective study. 61
30391793 2019
136
Multidisciplinary Treatment Intervention in 24 Patients with Oligodontia: A Case-Cohort Study. 61
30677108 2019
137
Prevalence of Hypodontia and Supernumerary Teeth in Patients Attending Private Pediatric Dental Clinic in Lebanon. 61
31560586 2019
138
Coexistence of tooth agenesis and ovarian cancer - a systematic literature review. 61
31909464 2019
139
A novel PTCH1 mutation in basal cell nevus syndrome with rare craniofacial features. 61
30962945 2019
140
KDF1 is a novel candidate gene of non-syndromic tooth agenesis. 61
30384154 2019
141
Third molar tooth agenesis and pattern of impaction in patients with palatally displaced canines. 61
30324806 2019
142
Tooth agenesis: part 1. Incidence and diagnosis in orthodontics. 61
30759978 2019
143
Tooth agenesis: part 2. Orthodontic treatment and prosthetic possibilities. 61
30966729 2019
144
A novel 14q13.1-21.1 deletion identified by CNV-Seq in a patient with brain-lung-thyroid syndrome, tooth agenesis and immunodeficiency. 61
31890031 2019
145
Establishment of an ectodermal dysplasia related gene EDA Knockout human embryonic stem cell line (WAe001-A-22) by CRISPR-Cas9 technology. 61
30605838 2019
146
Cephalometric Measurements Of Non-Syndromic Oligodontia In Early Dental Age In A Japanese Population. 61
31819657 2019
147
Occlusal Rehabilitation in a Patient with Oligodontia and Microdontia using Implants and Full-Ceramic Restorations: A Clinical Report. 61
31859288 2019
148
POLR3B-associated leukodystrophy: clinical, neuroimaging and molecular-genetic analyses in four patients: clinical heterogeneity and novel mutations in POLR3B gene. 61
31577365 2019
149
WNT10A variants in relation to nonsyndromic hypodontia in eastern Slovak population. 61
30555066 2018
150
Interceptive treatment in ectodermal dysplasia using an innovative orthodontic/prosthetic modular appliance. A case report with 10- year follow-up. 61
30567449 2018
151
Bi-allelic POLR3A Loss-of-Function Variants Cause Autosomal-Recessive Wiedemann-Rautenstrauch Syndrome. 61
30414627 2018
152
Non-syndromic tooth agenesis patterns and their association with other dental anomalies: A retrospective study. 61
30172942 2018
153
Further evidence for the role of WNT10A, WNT10B and GREM2 as candidate genes for isolated tooth agenesis. 61
30246922 2018
154
What factors affect the severity of permanent tooth impaction? 61
30382922 2018
155
Parental Perceptions of Prosthetic Treatment for and Coping Abilities of Children with Ectodermal Dysplasia: A Pilot Study. 61
31840646 2018
156
Patterns of Dental Agenesis Highlight the Nature of the Causative Mutated Genes. 61
29879364 2018
157
Dental implants with fixed prosthodontics in oligodontia: A retrospective cohort study with a follow-up of up to 25 years. 61
29703671 2018
158
Examination of craniofacial morphology in Japanese patients with congenitally missing teeth: a cross-sectional study. 61
30270414 2018
159
Agenesis of Permanent Canines in Orthodontic Patients: Prevalence, Location, Treatment Options and Outcomes. 61
30869590 2018
160
Homozygosity for CREB3L1 premature stop codon in first case of recessive osteogenesis imperfecta associated with OASIS-deficiency to survive infancy. 61
29936144 2018
161
Identification of likely pathogenic and known variants in TSPEAR, LAMB3, BCOR, and WNT10A in four Turkish families with tooth agenesis. 61
30046887 2018
162
Frequency of missing teeth and reduction of mesiodistal tooth width in Japanese patients with tooth agenesis. 61
30123921 2018
163
Nonsyndromic cleft lip and/or palate: A multicenter study of the dental anomalies involved. 61
30305871 2018
164
A novel mutation of MSX1 in oligodontia inhibits odontogenesis of dental pulp stem cells via the ERK pathway. 61
30134957 2018
165
Adverse effects of chemotherapy on the teeth and surrounding tissues of children with cancer: A systematic review with meta-analysis. 61
30098781 2018
166
Associations between tooth agenesis and displaced maxillary canines: a cross-sectional radiographic study. 61
30027405 2018
167
Tooth agenesis code (TAC) in complete unilateral and bilateral cleft lip and palate patients. 61
29243181 2018
168
Clinical Risk Factors Influencing Dental Developmental Disturbances in Childhood Cancer Survivors. 61
29020731 2018
169
Dental Anomalies in Different Types of Cleft Lip and Palate: Is There Any Relation? 61
29485555 2018
170
[Clinical features and mutational analysis of a case with Sensenbrenner syndrome]. 61
29896747 2018
171
Orthognathic surgery in Melnick-Needles syndrome: a review of the literature and report of two siblings. 61
29336932 2018
172
WNT10A mutation results in severe tooth agenesis in a family of three sisters. 61
29927056 2018
173
Maxillary Hypoplasia With Congenital Oligodontia Treated by Maxillary Distraction Osteogenesis. 61
29489572 2018
174
A novel PITX2 mutation in non-syndromic orodental anomalies. 61
29121437 2018
175
The Changing Landscape in the Genetic Etiology of Human Tooth Agenesis. 61
29772684 2018
176
Rare and Common Variants Conferring Risk of Tooth Agenesis. 61
29364747 2018
177
GREM2 nucleotide variants and the risk of tooth agenesis. 61
28992378 2018
178
WNT10B mutations associated with isolated dental anomalies. 61
29364501 2018
179
A biallelic ANTXR1 variant expands the anthrax toxin receptor associated phenotype to tooth agenesis. 61
29436111 2018
180
Rethinking isolated cleft lip and palate as a syndrome. 61
29500156 2018
181
Third molar agenesis as a potential marker for craniofacial deformities. 61
29358133 2018
182
Tooth agenesis: A susceptible indicator for colorectal cancer? 61
29893310 2018
183
Agenesis of all permanent maxillary incisors: A rare clinical case with an interdisciplinary solution. 61
29750104 2018
184
Long-term implant performance and patients' satisfaction in oligodontia. 61
29360491 2018
185
Dental anomalies in different growth and skeletal malocclusion patterns. 61
29215300 2018
186
Let-7b regulates alpaca hair growth by downregulating ectodysplasin A. 61
29344666 2018
187
A review on non-syndromic tooth agenesis associated with PAX9 mutations. 61
29628999 2018
188
Nine Novel PAX9 Mutations and a Distinct Tooth Agenesis Genotype-Phenotype. 61
28910570 2018
189
Colorectal Cancer-Associated Genes Are Associated with Tooth Agenesis and May Have a Role in Tooth Development. 61
29445242 2018
190
Mesenchymal Wnt/β-catenin signaling limits tooth number. 61
29437780 2018
191
Genetic study of non-syndromic tooth agenesis through the screening of paired box 9, msh homeobox 1, axin 2, and Wnt family member 10A genes: a case-series. 61
29114927 2018
192
Disturbances of dental development distinguish patients with oligodontia-ectodermal dysplasia from isolated oligodontia. 61
29271123 2018
193
Next generation sequencing reveals a novel nonsense mutation in MSX1 gene related to oligodontia. 61
30192788 2018
194
Biology Explaining Tooth Repair and Regeneration: A Mini-Review. 61
29533942 2018
195
Phenotypic Features and Salivary Parameters in Patients with Ectodermal Dysplasia: Report of Three Cases. 61
29854479 2018
196
Non-syndromic hypodontia of permanent dentition associated with other dental anomalies in children and adolescents. 61
30534829 2018
197
Diagnosis of Tooth Agenesis in Childhood and Risk for Neoplasms in Adulthood. 61
30559619 2018
198
Sanjad-Sakati Syndrome: Oral Health Care. 61
29533933 2018
199
Whole-Exome Sequencing Identifies Novel Variants for Tooth Agenesis. 61
28813618 2018
200
Investigation of prevalence of dental anomalies by using digital panoramic radiographs. 61
28933802 2018
201
Nonsyndromic cleft lip and palate, gastric cancer and tooth agenesis. 61
29274157 2018
202
Al-Awadi-Raas-Rothschild syndrome with dental anomalies and a novel WNT7A mutation. 61
28917830 2017
203
A cross-sectional analysis of the prevalence of tooth agenesis and structural dental anomalies in association with cleft type in non-syndromic oral cleft patients. 61
28681357 2017
204
Gene screening facilitates diagnosis of complicated symptoms: A case report. 61
28944914 2017
205
A novel PAX9 mutation causing oligodontia. 61
28965043 2017
206
Three-dimensional computer-guided implant placement in oligodontia. 61
28689266 2017
207
Role of WNT10A in failure of tooth development in humans and zebrafish. 61
29178643 2017
208
A novel G to A transition at initiation codon and exon-intron boundary of PAX9 identified in association with familial isolated oligodontia. 61
28847717 2017
209
Associations between ectodermal dysplasia, psychological distress and quality of life in a group of adults with oligodontia. 61
28754083 2017
210
A Comprehensive Craniofacial Study of 22q11.2 Deletion Syndrome. 61
28732176 2017
211
A novel finding of oligodontia and ankyloglossia in a 14-year-old with Floating-Harbor syndrome. 61
29210485 2017
212
Dental and extra-oral clinical features in 41 patients with WNT10A gene mutations: A multicentric genotype-phenotype study. 61
28105635 2017
213
PAX9 gene mutations and tooth agenesis: A review. 61
28155232 2017
214
Permanent tooth agenesis in individuals with non-syndromic Robin sequence: a systematic review and meta-analysis. 61
29027749 2017
215
Establishment of a congenital tooth agenesis related gene MSX1 knockout human embryonic stem cell lines by CRISPR-Cas9 technology. 61
29034883 2017
216
Novel EDA or EDAR Mutations Identified in Patients with X-Linked Hypohidrotic Ectodermal Dysplasia or Non-Syndromic Tooth Agenesis. 61
28981473 2017
217
Tooth Abnormalities In Individuals With Unilateral Alveolar Clefts: A Comparison Between Sides Using Cone-Beam Computed Tomography. 61
29167708 2017
218
The Biology Underlying Abnormalities of Tooth Number in Humans. 61
28783411 2017
219
Permanent tooth agenesis in non-syndromic Robin sequence and cleft palate: prevalence and patterns. 61
27933446 2017
220
TFAP2B mutation and dental anomalies. 61
28381879 2017
221
Craniofacial shape differs in patients with tooth agenesis: geometric morphometric analysis. 61
27464525 2017
222
Morphometric covariation between palatal shape and skeletal pattern in children and adolescents: a cross-sectional study. 61
27694577 2017
223
EDA mutation by exome sequencing in non-syndromic X-linked oligodontia. 61
28052341 2017
224
Evaluation of the skeletal and dental effects in orthodontic patients with maxillary lateral incisor agenesis. 61
28560844 2017
225
Mutations in AXIN2 gene as a risk factor for tooth agenesis and cancer: A review. 61
28759178 2017
226
Patterns of non-syndromic permanent tooth agenesis in a large orthodontic population. 61
28288390 2017
227
Acromelia-oligodontia syndrome. 61
28588849 2017
228
Contemporary surgical management of hypodontia. 61
28410841 2017
229
Oral Rehabilitation of a Patient With Ectodermal Dysplasia Treated With Fresh-Frozen Bone Allografts and Computer-Guided Implant Placement: A Clinical Case Report. 61
28208056 2017
230
Dental anomaly patterns associated with tooth agenesis. 61
28121195 2017
231
Association between Tooth Agenesis and Skeletal Malocclusions. 61
28791079 2017
232
Blepharocheilodontic (BCD) syndrome: New insights on craniofacial and dental features. 61
28181393 2017
233
Nonsyndromic oligodontia : Does the Tooth Agenesis Code (TAC) enable prediction of the causative mutation? 61
28204848 2017
234
Non-syndromic severe hypodontia caused by a novel frameshift insertion mutation in the homeobox of the MSX1 gene. 61
27951410 2017
235
Dental anomalies: prevalence and associations between them in a large sample of non-orthodontic subjects, a cross-sectional study. 61
28284207 2017
236
Genetic Disorders of Dental Development: Tales from the Bony Crypt. 61
28124261 2017
237
Management of missing mandibular second premolars: a review. 61
29709125 2017
238
Second premolar agenesis as a subclinical phenotype of isolated cleft palate. 61
27860241 2017
239
Novel IRF6 Mutations Detected in Orofacial Cleft Patients by Targeted Massively Parallel Sequencing. 61
27834299 2017
240
Pyramidal and Taurodont Molars and Their Association With Other Tooth Anomalies. 61
28292341 2017
241
Prevalence of dental anomalies in deciduous dentition and its association with succedaneous dentition: A cross-sectional study of 4180 South Indian children. 61
28139484 2017
242
Prevalence of delayed tooth development and its relation to tooth agenesis in Korean children. 61
27810381 2017
243
Comprehensive genetic exploration of selective tooth agenesis of mandibular incisors by exome sequencing. 61
28265457 2017
244
Characterization of PAX9 variant P20L identified in a Japanese family with tooth agenesis. 61
29023497 2017
245
Association between EDAR Polymorphisms and Non-Syndromic Tooth Agenesis in the Chinese Han Population. 61
28808699 2017
246
WNT10A variants isolated from Japanese patients with congenital tooth agenesis. 61
29367877 2017
247
Tooth agenesis in osteogenesis imperfecta related to mutations in the collagen type I genes. 61
27510842 2017
248
Evaluation of Masticatory Stimulation Effect on the Maxillary Transversal Growth in Ectodermal Dysplasia Children. 61
28377657 2017
249
Combined Orthodontic and Restorative Approach to Esthetic Treatment of Maxillary Peg Lateral Incisor in Adolescent Female Patient: Case Report. 61
29916685 2017
250
Endodontic Management of an Infected Primary Molar in a Child with Agenesis of the Permanent Premolar. 61
28179938 2017
251
Hypodontia: An Update on Its Etiology, Classification, and Clinical Management. 61
28401166 2017
252
Agenesis of Third Molars among Turkish Children between the Ages of 12 and 18 Years: A Retrospective Radiographic Study. 61
28422596 2017
253
Influence of Deformation and Stress between Bone and Implant from Various Bite Forces by Numerical Simulation Analysis. 61
28630862 2017
254
Patterns of incisor-premolar agenesis combinations: A retrospective study. 61
28139483 2017
255
Bmp4-Msx1 signaling and Osr2 control tooth organogenesis through antagonistic regulation of secreted Wnt antagonists. 61
27713059 2016
256
Tooth agenesis and orofacial clefting: genetic brothers in arms? 61
27699475 2016
257
MSX1 mutations and associated disease phenotypes: genotype-phenotype relations. 61
27381090 2016
258
A novel heterozygous mutation in desmoplakin gene in a Lebanese patient with Carvajal syndrome and tooth agenesis. 61
26833927 2016
259
Genetic Basis of Nonsyndromic and Syndromic Tooth Agenesis. 61
27895972 2016
260
Novel human mutation and CRISPR/Cas genome-edited mice reveal the importance of C-terminal domain of MSX1 in tooth and palate development. 61
27917906 2016
261
Dental Anomalies in a Brazilian Cleft Population. 61
26575968 2016
262
Dental anomalies in an orthodontic patient population with maxillary lateral incisor agenesis. 61
28125145 2016
263
Abnormal primary and permanent dentitions with ectodermal symptoms predict WNT10A deficiency. 61
27881089 2016
264
Mutation analysis by direct and whole exome sequencing in familial and sporadic tooth agenesis. 61
27665865 2016
265
Novel mutations in LRP6 highlight the role of WNT signaling in tooth agenesis. 61
26963285 2016
266
Effects of PAX9 and MSX1 gene variants to hypodontia, tooth size and the type of congenitally missing teeth. 61
28040065 2016
267
Characterization of a novel mutation in PAX9 gene in a family with non-syndromic dental agenesis. 61
27491081 2016
268
Role of the Wnt signaling molecules in the tooth. 61
28408959 2016
269
Association between hypodontia and Angles malocclusion. 61
27895346 2016
270
A novel MSX1 intronic mutation associated with autosomal dominant non-syndromic oligodontia in a large Chinese family pedigree. 61
27485761 2016
271
Mutation of KREMEN1, a modulator of Wnt signaling, is responsible for ectodermal dysplasia including oligodontia in Palestinian families. 61
27049303 2016
272
Genetics: The Future Is Now with Interprofessional Collaboration. 61
27671963 2016
273
Autosomal dominant Carvajal plus syndrome due to the novel desmoplakin mutation c.1678A > T (p.Ile560Phe). 61
28649555 2016
274
Midfacial Protraction With Skeletal Anchorage After Pterygomaxillary Separation. 61
27428915 2016
275
Long-term effect of chemotherapy-intensity-modulated radiation therapy (chemo-IMRT) on dentofacial development in head and neck rhabdomyosarcoma patients. 61
27689858 2016
276
Multidisciplinary Management of Oligodontia in the Adolescent. 61
29182258 2016
277
Alteration of palatine ruga pattern in subjects with oligodontia: A pilot study. 61
27476363 2016
278
De novo EDA mutations: Variable expression in two Egyptian families. 61
27054699 2016
279
Mutations in MSX1, PAX9 and MMP20 genes in Saudi Arabian patients with tooth agenesis. 61
27365112 2016
280
[EDA mutation screening and phenotype analysis in patients with tooth agenesis]. 61
29263514 2016
281
Prevalence and patterns of permanent tooth agenesis in individuals with Down syndrome: a meta-analysis. 61
27311636 2016
282
Functional analysis of a novel missense mutation in AXIN2 associated with non-syndromic tooth agenesis. 61
27090353 2016
283
Rehabilitation of a patient with non-syndromic partial oligodontia. 61
27350861 2016
284
Waardenburg syndrome type I: Dental phenotypes and genetic analysis of an extended family. 61
27031059 2016
285
A Digital Approach to Improved Overdentures for the Adolescent Oligodontia Patient. 61
27154432 2016
286
Hypodontia, a prospective predictive marker for tumor? 61
26600092 2016
287
Prosthodontic Rehabilitation with a Telescopic Prosthesis of a Nonsyndromic Oligodontia Patient. 61
26032146 2016
288
Early functional, esthetic, and psychological rehabilitation of preschool child with nonsyndromic oligodontia and anodontia in mixed dentition stage through conservative systematic approach: A case report with 5-year follow-up. 61
27307674 2016
289
WNT10A polymorphism may be a risk factor for non-syndromic hypodontia. 61
27050986 2016
290
Odonto-onycho-dermal dysplasia in a patient homozygous for a WNT10A nonsense mutation and mild manifestations of ectodermal dysplasia in carriers of the mutation. 61
26964878 2016
291
Clinical and Radiographic Evaluation of a Small-Diameter Dental Implant Used for the Restoration of Patients with Permanent Tooth Agenesis (Hypodontia) in the Maxillary Lateral Incisor and Mandibular Incisor Regions: A 36-Month Follow-Up. 61
26929953 2016
292
A targeted next-generation sequencing assay for the molecular diagnosis of genetic disorders with orodental involvement. 61
26502894 2016
293
[EDA mutation screening and phenotype analysis in patients with tooth agenesis]. 61
27538153 2016
294
Genetic Variants of BMP2 and Their Association with the Risk of Non-Syndromic Tooth Agenesis. 61
27362534 2016
295
Functional Study of Ectodysplasin-A Mutations Causing Non-Syndromic Tooth Agenesis. 61
27144394 2016
296
DNA methylation is critical for tooth agenesis: implications for sporadic non-syndromic anodontia and hypodontia. 61
26759063 2016
297
Antineoplastic chemotherapy and congenital tooth abnormalities in children and adolescents. 61
28373822 2016
298
Carvajal syndrome with oligodontia, hypoacusis, recurrent infections, and noncompaction. 61
26599742 2016
299
Dental anomalies inside the cleft region in individuals with nonsyndromic cleft lip with or without cleft palate. 61
26615505 2016
300
The association between WNT10A variants and dental development in patients with isolated oligodontia. 61
27650966 2016
301
Possible association between acetazolamide administration during pregnancy and multiple congenital malformations. 61
27143854 2016
302
Antagonistic Functions of USAG-1 and RUNX2 during Tooth Development. 61
27518316 2016
303
A novel initiation codon mutation of PAX9 in a family with oligodontia. 61
26571067 2016
304
Symmetrical agenesis of the mandibular third molars and agenesis of other teeth in a Japanese orthodontic population. 61
27349537 2016
305
Novel missense mutation in the EDA gene in a family affected by oligodontia. 61
26753551 2016
306
Patterns of bilateral agenesis of maxillary third molars and agenesis of other teeth. 61
25636272 2016
307
Diagnosis and Management of a Patient with Congenitally Missing Maxillary First Permanent Molars: A Rare Case Report. 61
27525130 2016
308
Surgically Assisted Orthodontics: Use of Piezocision in a Case of Oligodontia to Accelerate the Rate of Tooth Movement. 61
27319046 2016
309
Gene responsible for oligodontia found, say researchers. 61
26942238 2015
310
A simplified approach for prosthodontic management of syndromic oligodontia. 61
26858479 2015
311
[Investigation of teeth number and morphology abnormalities in children at the mixed dentition stage]. 61
27051952 2015
312
GREMLIN 2 Mutations and Dental Anomalies. 61
26416033 2015
313
Prevalence and distribution of dental anomalies: a comparison between maxillary and mandibular tooth agenesis. 61
26522039 2015
314
Permanent Tooth Agenesis and Maxillary Hypoplasia in Patients with Unilateral Cleft Lip and Palate. 61
26505722 2015
315
Ultra-Thin Veneers Without Tooth Preparation in Extensive Oligodontia. 61
26509995 2015
316
Mesiodistal inclination of the unerupted second premolar in the mandible of Japanese orthodontic patients with incisor agenesis. 61
25757185 2015
317
Intermediate rehabilitation with (non)-prep all-ceramic onlays in an adolescent patient with oligodontia--4-year follow-up. 61
25109372 2015
318
A multidisciplinary treatment of patients with craniofacial disorders. Own experience. 61
26982754 2015
319
Prosthodontic Treatment for Severe Oligodontia with Long-term Follow-up. 61
26485508 2015
320
Further delineation of the KBG syndrome phenotype caused by ANKRD11 aberrations. 61
25424714 2015
321
Genetic epidemiology of tooth agenesis in Japan: a population- and family-based study. 61
25041097 2015
322
Noninvasive Prenatal Diagnosis of Hypohidrotic Ectodermal Dysplasia by Tooth Germ Sonography. 61
25140498 2015
323
Beni Solow Award 2014. 61
26209690 2015
324
The Gene Network Underlying Hypodontia. 61
25910507 2015
325
A novel frameshift MSX1 mutation in a Saudi family with autosomal dominant premolar and third molar agenesis. 61
25874811 2015
326
Bilateral Hypodontia in Adolescents With Pierre Robin Sequence. 61
25058123 2015
327
Prevalence and patterns of tooth agenesis in Angle Class II Division 2 malocclusion in Japan. 61
26124035 2015
328
Erratum to: Living with orofacial conditions: psychological distress and quality of life in adults affected with Treacher Collins syndrome, cherubism, or oligodontia/ectodermal dysplasia--a comparative study. 61
25480422 2015
329
The functional EGF+61 polymorphism and nonsyndromic oral clefts susceptibility in a Brazilian population. 61
26398511 2015
330
New recessive truncating mutation in LTBP3 in a family with oligodontia, short stature, and mitral valve prolapse. 61
25899461 2015
331
Association of BMP4 polymorphisms with isolated tooth agenesis in a Chinese Han population: a case-control study. 61
26166641 2015
332
A Nonsyndromic Autosomal Dominant Oligodontia with A Novel Mutation of PAX9-A Clinical and Genetic Report. 61
26266225 2015
333
Relationship between the maxillary transverse dimension and palatally displaced canines: A cone-beam computed tomographic study. 61
25098187 2015
334
Agenesis of multiple primary and permanent teeth unilaterally and its possible management. 61
26028909 2015
335
An evaluation of clinical, radiological and three-dimensional dental tomography findings in ectodermal dysplasia cases. 61
25662550 2015
336
An AXIN2 Mutant Allele Associated With Predisposition to Colorectal Neoplasia Has Context-Dependent Effects on AXIN2 Protein Function. 61
26025668 2015
337
Living with orofacial conditions: psychological distress and quality of life in adults affected with Treacher Collins syndrome, cherubism, or oligodontia/ectodermal dysplasia-a comparative study. 61
25344415 2015
338
Identical deletion at 14q13.3 including PAX9 and NKX2-1 in siblings from mosaicism of unaffected parent. 61
25608831 2015
339
A screen of a large Czech cohort of oligodontia patients implicates a novel mutation in the PAX9 gene. 61
25683653 2015
340
Limitations of a method used for adolescent assessment of smile aesthetics. 61
25016580 2015
341
Dental implants are a viable alternative for compensating oligodontia in adolescents. 61
24383943 2015
342
Familial Hypodontia: A Case Series. 61
26643836 2015
343
Axis inhibition protein 2 polymorphisms may be a risk factor for families with isolated oligodontia. 61
25377791 2015
344
Distribution of permanent canine agenesis in Down syndrome: 15 cases from a Centre for Special Care Dentistry. 61
25081021 2015
345
Determination of vertical dimension in prosthodontic rehabilitation of a growing patient with severe oligodontia. 61
25793956 2015
346
An interdisciplinary noninvasive all-ceramic treatment concept for nonsyndromic oligodontia in adolescence. 61
25191671 2015
347
[BMP2/BMP4 genetic evaluation in 40 patients with tooth agenesis]. 61
25858375 2015
348
Prevalence of tooth agenesis in adolescent Chinese populations with or without orthodontics. 61
25815384 2015
349
Novel PAX9 gene polymorphisms and mutations and susceptibility to tooth agenesis in the Czech population. 61
26707046 2015
350
Retrospective Study of Association between Displacement of Maxillary Canine and Tooth Agenesis. 61
26551375 2015
351
An aberrant splice acceptor site due to a novel intronic nucleotide substitution in MSX1 gene is the cause of congenital tooth agenesis in a Japanese family. 61
26030286 2015
352
The prevalence of dental anomalies in a turkish population. 61
28955542 2015
353
[Optimization of diagnostics and orthodontic treatment planning in children and adolescents with multiply adentia]. 61
26331177 2015
354
[In Process Citation]. 61
26631270 2015
355
Taurodontism, variations in tooth number, and misshapened crowns in Wnt10a null mice and human kindreds. 61
25629078 2015
356
Oligodontia in a teenager with Down syndrome - a case study. 61
25338122 2015
357
A Novel AXIN2 Missense Mutation Is Associated with Non-Syndromic Oligodontia. 61
26406231 2015
358
Conventional Complete Denture in Patients with Ectodermal Dysplasia. 61
26425372 2015
359
Bilateral agenesis of maxillary permanent canines: Review of the literature. 61
25657989 2015
360
Local anesthetics induce autophagy in young permanent tooth pulp cells. 61
27551457 2015
361
Simultaneous Occurence of an Autosomal Dominant Inherited MSX1 Mutation and an X-linked Recessive Inherited EDA Mutation in One Chinese Family with Non-syndromic Oligodontia. 61
26629556 2015
362
Maxillary dental anomalies in patients with cleft lip and palate: a cone beam computed tomography study. 61
25823490 2015
363
Association between third molar agenesis patterns and agenesis of other teeth in a Japanese orthodontic population. 61
23990107 2015
364
Prevalence of hypodontia and associated factors: a systematic review and meta-analysis. 61
25404667 2014
365
Interstitial 12p deletion involving more than 40 genes in a patient with postnatal microcephaly, psychomotor delay, optic nerve atrophy, and facial dysmorphism. 61
25606391 2014
366
Intragenic duplication--a novel causative mechanism for SATB2-associated syndrome. 61
25251319 2014
367
Skeletal malocclusion: a developmental disorder with a life-long morbidity. 61
25247012 2014
368
[WNT 10A-mutations as explanation for tooth agenesis]. 61
26188476 2014
369
Association of MSX1 and TGF-β1 genetic polymorphisms with hypodontia: meta-analysis. 61
25501212 2014
370
PAX-9 polymorphism may be a risk factor for hypodontia: a meta-analysis. 61
25501211 2014
371
Autogenous premolar transplantation into artificial socket in maxillary lateral incisor site. 61
25134733 2014
372
Mutations in the MSX1 gene in Turkish children with non-syndromic tooth agenesis and other dental anomalies. 61
25565750 2014
373
A study of prevalence and distribution of tooth agenesis. 61
25713620 2014
374
The WNT10A gene in ectodermal dysplasias and selective tooth agenesis. 61
24700731 2014
375
Orodental manifestations in ectodermal dysplasia-a review. 61
24719393 2014
376
Msx1 role in craniofacial bone morphogenesis. 61
24929242 2014
377
Variability in dentofacial phenotypes in four families with WNT10A mutations. 61
24398796 2014
378
Non-syndromic oligodontia in permanent dentition: a case report. 61
25709129 2014
379
A novel non-stop mutation in MSX1 causing autosomal dominant non-syndromic oligodontia. 61
24914010 2014
380
Using implants for prosthodontic rehabilitation of a 4-year-old with ectodermal dysplasia. 61
25184725 2014
381
Dento-maxillo-facial phenotype and implants-based oral rehabilitation in Ectodermal Dysplasia with WNT10A gene mutation: report of a case and literature review. 61
24702986 2014
382
From childhood to adulthood: oral rehabilitation of a patient with ectodermal dysplasia. 61
24831743 2014
383
Implant-retained overdentures for young children with severe oligodontia: a series of four cases. 61
25109582 2014
384
Bilateral maxillary canine-first premolar transposition in permanent dentition. 61
25149842 2014
385
Bilateral hypodontia is more common than unilateral hypodontia in children with Down syndrome: a prospective population-based study. 61
24014738 2014
386
Assessing the association of taurodontism with numeric dentition anomalies in an adult central Indian population. 61
25097429 2014
387
Labial ankyloglossia associated with oligodontia: a case report. 61
25584061 2014
388
A novel WNT10A mutation causes non-syndromic hypodontia in an Egyptian family. 61
24798981 2014
389
Esthetic rehabilitation of a patient with severe oligodontia. 61
24502758 2014
390
Nonsyndromic oligodontia in siblings: A rare case report. 61
25210374 2014
391
Evaluation of tooth number anomalies in a subpopulation of the North-East of Turkey. 61
25202213 2014
392
Bilateral agenesis of permanent mandibular central incisors: report of two cases. 61
25083043 2014
393
Blepharo-cheilo-dontic (BCD) syndrome: expanding the phenotype, case report and review of literature. 61
24719364 2014
394
Wolf-Hirschhorn syndrome (WHS) - literature review on the features of the syndrome. 61
24979523 2014
395
EDAR-induced hypohidrotic ectodermal dysplasia: a clinical study on signs and symptoms in individuals with a heterozygous c.1072C > T mutation. 61
24884697 2014
396
Exclusion of PAX9 and MSX1 mutation in six families affected by tooth agenesis. A genetic study and literature review. 61
24316698 2014
397
Identification of genetic risk factors for maxillary lateral incisor agenesis. 61
24554542 2014
398
[Association between AXIN2 polymorphism and oligodontia]. 61
24743819 2014
399
Interdisciplinary treatment of a nonsyndromic oligodontia patient with implant-anchored orthodontics. 61
24680022 2014
400
Complex analysis of multiple single nucleotide polymorphisms as putative risk factors of tooth agenesis in the Hungarian population. 61
23964635 2014
401
Association between rs11001553 of DKK1 and non-syndromic tooth agenesis in the Chinese Han population. 61
24737523 2014
402
Prevalence and patterns of permanent tooth agenesis in patients with nonsyndromic Pierre Robin sequence. 61
24703283 2014
403
Tricho-odonto-onycho-dermal dysplasia and WNT10A mutations. 61
24458874 2014
404
Oligodontia and curly hair occur with ectodysplasin-a mutations. 61
24487376 2014
405
Three novel GJA1 missense substitutions resulting in oculo-dento-digital dysplasia (ODDD) - further extension of the mutational spectrum. 61
24508941 2014
406
Is there a link between ovarian cancer and tooth agenesis? 61
24631698 2014
407
Prevalence of second premolar hypodontia in the Polish cleft lip and palate population. 61
24584216 2014
408
Patterns of tooth agenesis in patients with crouzon or apert syndrome. 61
23126314 2014
409
Colorectal cancer and self-reported tooth agenesis. 61
24607150 2014
410
Rehabilitation of medically complex ectodermal dysplasia with novel surgical and prosthodontic protocols. 61
24035129 2014
411
Prevalence of dental anomalies among 7- to 35-year-old people in Hamadan, Iran in 2012-2013 as observed using panoramic radiographs. 61
24701453 2014
412
Novel PAX9 mutations cause non-syndromic tooth agenesis. 61
24436340 2014
413
Prevalence and patterns of tooth agenesis among Malay children. 61
24968691 2014
414
Novel missense mutations in the AXIN2 gene associated with non-syndromic oligodontia. 61
24581859 2014
415
Deep submersion: severe phenotype of deciduous-molar infraocclusion with biological associations. 61
24001108 2014
416
Genetic basis of dental agenesis--molecular genetics patterning clinical dentistry. 61
24121910 2014
417
Novel nonsense mutation in MSX1 in familial nonsyndromic oligodontia: subcellular localization and role of homeodomain/MH4. 61
24329876 2014
418
Ion channels, channelopathies, and tooth formation. 61
24076519 2014
419
Tooth agenesis patterns and phenotype variation in a cohort of Belgian patients with hypodontia and oligodontia clustered in 79 families with their pedigrees. 61
23598609 2014
420
Whole genome sequencing reveals novel non-synonymous mutation in ectodysplasin A (EDA) associated with non-syndromic X-linked dominant congenital tooth agenesis. 61
25203534 2014
421
WNT10A variants are associated with non-syndromic tooth agenesis in the general population. 61
24043634 2014
422
Characterization of novel MSX1 mutations identified in Japanese patients with nonsyndromic tooth agenesis. 61
25101640 2014
423
A rare case of osteogenesis imperfecta combined with complete tooth loss. 61
23934635 2014
424
IRF6 AP-2a binding site promoter polymorphism is associated with oral clefts in Latvia. 61
25896037 2014
425
A newly identified missense mutation of the EDA1 gene in a Hungarian patient with Christ-Siemens-Touraine syndrome. 61
23989902 2014
426
A novel PITX2 mutation causing iris hypoplasia. 61
27081499 2014
427
Unilateral maxillary canine agenesis: a case report and literature review. 61
25177502 2014
428
Clinical and genetic analysis of a nonsyndromic oligodontia in a child. 61
25215247 2014
429
Molecular patterning of the mammalian dentition. 61
24355560 2014
430
Candidate gene studies in hypodontia suggest role for FGF3. 61
23549991 2013
431
A comparison of skeletal maturation in patients with tooth agenesis and unaffected controls assessed by the cervical vertebral maturation (CVM) index. 61
24297960 2013
432
A genome-wide association study of third molar agenesis in Japanese and Korean populations. 61
24172245 2013
433
Prosthodontic management of a patient with ectodermal dysplasia. 61
24304998 2013
434
Different manifestations of class II division 2 incisor retroclination and their association with dental anomalies. 61
24297961 2013
435
MSX1 and PAX9 investigation in monozygotic twins with variable expression of tooth agenesis. 61
24103583 2013
436
Associations between the risk of tooth agenesis and single-nucleotide polymorphisms of MSX1 and PAX9 genes in nonsyndromic cleft patients. 61
23718693 2013
437
Nucleotide variants of genes encoding components of the Wnt signalling pathway and the risk of non-syndromic tooth agenesis. 61
23167694 2013
438
Discordant tooth agenesis and peg-shaped in a pair of monozygotic twins: Clinical and molecular study. 61
24379875 2013
439
[Analysis of dental agenesis patterns of the oligodontia patients using the method of tooth agenesis code]. 61
24513068 2013
440
Developmental disorders of the dentition: an update. 61
24124058 2013
441
BMP4 Polymorphism is Associated With Nonsyndromic Oral Cleft in a Brazilian Population. 61
23237431 2013
442
Bilateral missing lower permanent incisors: a case report. 61
24380140 2013
443
Msx1 Gene Variant - its Association in Isolated Hypodontia: A Case Control Genetic study!!! 61
24497713 2013
444
MSX1 gene variant - its presence in tooth absence - a case control genetic study. 61
24324300 2013
445
Prosthodontic rehabilitation in patient with ectodermal dysplasia combining preprosthetic techniques: a case report. 61
24013396 2013
446
Mutational analysis of AXIN2, MSX1, and PAX9 in two Mexican oligodontia families. 61
24222224 2013
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A 3-year prospective study of implant-supported, single-tooth restorations of all-ceramic and metal-ceramic materials in patients with tooth agenesis. 61
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An inductive signalling network regulates mammalian tooth morphogenesis with implications for tooth regeneration. 61
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PAX9 polymorphisms and susceptibility with sporadic tooth agenesis in Turkish populations: a case-control study. 61
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Novel PAX9 mutation associated with syndromic tooth agenesis. 61
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Achondroplasia with oligodontia: Report of a rare case. 61
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Patient with oligodontia treated with a miniscrew for unilateral mesial movement of the maxillary molars and alignment of an impacted third molar. 61
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Isolated oligodontia in monozygotic twins. 61
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Clinical and genetic evaluation of a Chinese family with isolated oligodontia. 61
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The prevalence and distribution pattern of hypodontia among orthodontic patients in Southern Iran. 61
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A network of transcription factors operates during early tooth morphogenesis. 61
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[Identification of mutation in PAX9 gene in a Mongolian family with non-syndromic oligodontia]. 61
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Functional evaluation of a novel tooth agenesis-associated bone morphogenetic protein 4 prodomain mutation. 61
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[Research progress on gene involved in tooth agenesis]. 61
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Patterns of tooth agenesis in patients with orofacial clefts. 61
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Patterns of tooth agenesis in Japanese subjects with bilateral agenesis of mandibular second premolars. 61
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Prevalence of Dental Anomalies in Patients With Nonsyndromic Cleft Lip and/or Palate in a Brazilian Population. 61
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Genetic background of nonsyndromic oligodontia: a systematic review and meta-analysis. 61
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Tooth agenesis patterns in unilateral cleft lip and palate in humans. 61
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Comparison of mesiodistal crown dimension and arch width in subjects with and without hypodontia. 61
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Three-dimensional analysis of tooth dimensions in the MSX1-missense mutation. 61
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Dental anomalies in a Portuguese population. 61
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The impact of tooth agenesis on oral health-related quality of life in children. 61
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Non-syndromic tooth agenesis associated with a nonsense mutation in ectodysplasin-A (EDA). 61
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Recessive oligodontia linked to a homozygous loss-of-function mutation in the SMOC2 gene. 61
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Risk factors to cause tooth formation anomalies in chemotherapy of paediatric cancers. 61
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Non-syndromic oligodontia of primary and permanent dentition: 5 year follow up- a rare case report. 61
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Immediate loading rehabilitation of a severe oligodontia: minimum impact on a young patient's social life. 61
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[Sandwich osteotomy--a biologic method for vertical augmentation of edentulous alveolar ridges]. 61
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Dental and maxillofacial characteristics of six Japanese individuals with ectrodactyly-ectodermal dysplasia-clefting syndrome. 61
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Prevalence of tooth agenesis in orthodontic patient population in Western New York. 61
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Prosthetic rehabilitation interventions in adolescents with fixed bridges: a 5-year observational study. 61
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Tooth agenesis association with self-reported family history of cancer. 61
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Genetics of tooth agenesis: how to move the field forward. 61
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Nonsyndromic tooth agenesis patterns and associated developmental dental anomalies: a literature review with radiographic illustrations. 61
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Genetic variations in MMP9 and MMP13 contribute to tooth agenesis in a Brazilian population. 61
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Novel missense mutation in PAX9 gene associated with familial tooth agenesis. 61
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rs929387 of GLI3 is involved in tooth agenesis in Chinese Han population. 61
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Involvement of and interaction between WNT10A and EDA mutations in tooth agenesis cases in the Chinese population. 61
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Evaluation of tooth size in patients with congenitally-missing teeth. 61
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The original family revisited after 37 years: odontoma-dysphagia syndrome is most likely caused by a microduplication of chromosome 11q13.3, including the FGF3 and FGF4 genes. 61
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Multidisciplinary therapy of extensive oligodontia: a case report. 61
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Prosthetic rehabilitation in children: an alternative clinical technique. 61
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Aesthetic rehabilitation of oligodontia in primary dentition with adhesive partial denture. 61
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Nonsyndromic familial oligodontia with multiple dens invaginatus: a case report of an unusual case. 61
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Candidate gene analysis of tooth agenesis identifies novel mutations in six genes and suggests significant role for WNT and EDA signaling and allele combinations. 61
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PAX9 polymorphism and susceptibility to sporadic non-syndromic severe anodontia: a case-control study in southwest China. 61
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Association of agenesis of mandibular lateral incisors with other dental anomalies in a Japanese population. 61
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Developmental basis of toothlessness in turtles: insight into convergent evolution of vertebrate morphology. 61
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[Severe hypodontia in permanent dentition. Orthodontic treatment of oligodontia in children]. 61
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Studies on dentition and oral disorders of Camels in Maiduguri Abattoir, Borno State, Nigeria. 61
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Oligodontia with taurodontism in monozygous twins. 61
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Molecular factors resulting in tooth agenesis and contemporary approaches for regeneration: a review. 61
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A novel SPRY2 and SPRY4 interaction increases tooth agenesis susceptibility. 61
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Long-term follow-up of implant treatment for oligodontia in an actively growing individual: a clinical report. 61
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Dental anomalies in children born with clefts: a case-control study. 61
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Expanding the phenotype associated with a desmoplakin dominant mutation: Carvajal/Naxos syndrome associated with leukonychia and oligodontia. 61
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Phenotype characterization and sequence analysis of BMP2 and BMP4 variants in two Mexican families with oligodontia. 61
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Multidisciplinary approach for the aesthetic treatment of maxillary lateral incisors agenesis: thinking about implants? 61
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Is missing maxillary lateral incisor in complete cleft lip and palate a product of genetics or local environment? 61
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Non syndromic oligodontia: case report. 61
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Polymorphism in the MSX1 gene in a family with upper lateral incisor agenesis. 61
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Oligodontia--treatment planning of a case. 61
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A case-control study of the association between tooth-development gene polymorphisms and non-syndromic hypodontia in the Chinese Han population. 61
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From the transcription of genes involved in ectodermal dysplasias to the understanding of associated dental anomalies. 61
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Association of common PAX9 variants with permanent tooth size variation in non-syndromic East Asian populations. 61
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Relationship between dental anomalies and orthodontic root resorption of upper incisors. 61
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Phenotypic findings in Chinese families with X-linked hypohydrotic ectodermal dysplasia. 61
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Tooth transposition: a descriptive study in a 547-patient sample. 61
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Esthetic and functional rehabilitation for oligodontia in the mixed dentition: case report. 61
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Famlial nonsyndromic oligodontia. 61
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Orthognathic surgery of a patient with oligodontia: alternative technique for intermaxillary fixation. 61
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Implant-prosthetic rehabilitation of a patient with nonsyndromic oligodontia: a clinical report. 61
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Isolated aglossia congenita: A rare case of oromandibular limb hypogenesis syndrome type I B. 61
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Oral manifestations of patients with Kenny-Caffey Syndrome. 61
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Taurodontism in Brazilian patients with tooth agenesis and first and second-degree relatives: a case-control study. 61
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Novel nonsense mutation in MSX1 causes tooth agenesis with cleft lip in a Chinese family. 61
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The use of onplants and implants in children with severe oligodontia: a retrospective evaluation. 61
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Novel missense mutations in PAX9 causing oligodontia. 61
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Novel MSX1 mutation in a family with autosomal-dominant hypodontia of second premolars and third molars. 61
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Tooth agenesis in a Portuguese population. 61
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Defining predictors of cleft lip and palate risk. 61
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Dental developmental disturbances in 50 individuals with the 22q11.2 deletion syndrome; relation to medical conditions? 61
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Tooth size reduction and agenesis associated with palatally displaced canines. 61
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Left-sided predominance of hypodontia irrespective of cleft sidedness in a French population. 61
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Evidence for genetic heterogeneity in Carvajal syndrome. 61
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NEMO syndrome (incontinentia pigmenti) and systemic lupus erythematosus: a new disease association. 61
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TGFB3 and BMP4 polymorphism are associated with isolated tooth agenesis. 61
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A novel nonsense mutation in PAX9 is associated with sporadic hypodontia. 61
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Dental manifestations of a pediatric patient with hyperimmunoglobulin e syndrome: a case report. 61
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Root resorption of primary molars without successor teeth. An experimental study in the beagle dog. 61
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Multidisciplinary treatment of non-syndromic oligodontia. 61
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Dentistry and molecular biology: a promising field for tooth agenesis management. 61
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Dental impactions related to pseudoxanthoma elasticum. 61
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TBX22 mutation associated with cleft lip/palate, hypodontia, and limb anomaly. 61
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Prevalence of dental anomalies in nonsyndromic individuals with cleft lip and palate: a systematic review and meta-analysis. 61
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Radiographic study of prevalence and distribution of hypodontia in a pediatric orthodontic population in Venezuela. 61
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Prevalence and intra-oral distribution of agenesis of permanent teeth among Eastern Turkish children. 61
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Revision of "A 223-kb de novo deletion of PAX9 in a patient with oligodontia". 61
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Fahr's disease with oral manifestations: report of a rare case. 61
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Interaction between IRF6 and TGFA genes contribute to the risk of nonsyndromic cleft lip/palate. 61
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Novel PAX9 and COL1A2 missense mutations causing tooth agenesis and OI/DGI without skeletal abnormalities. 61
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An insight into the genesis of hypohidrotic ectodermal dysplasia in a case report. 61
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Homozygosity mapping and candidate prioritization identify mutations, missed by whole-exome sequencing, in SMOC2, causing major dental developmental defects. 61
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Patterns of third-molar agenesis and associated dental anomalies in an orthodontic population. 61
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Understanding the implications of the PAX9 gene in tooth development. 61
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Recessive mutations in POLR3B, encoding the second largest subunit of Pol III, cause a rare hypomyelinating leukodystrophy. 61
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A novel heterozygous point mutation in the p63 gene in a patient with ectodermal dysplasia associated with B-cell leukemia. 61
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Severe oligodontia and dental anomalies in a child with a history of multiple natal teeth: An eight-year retrospective. 61
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Dental development and tooth agenesis in children with velocardiofacial syndrome. 61
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Sequence analysis of PAX9, MSX1 and AXIN2 genes in a Chinese oligodontia family. 61
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A rat model of hypohidrotic ectodermal dysplasia carries a missense mutation in the Edaradd gene. 61
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Review of ectodermal dysplasia: case report on treatment planning and surgical management of oligodontia with implant restorations. 61
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Ellis van Creveld syndrome--a report of two siblings. 61
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Genetic basis for tooth malformations: from mice to men and back again. 61
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Maxillary sagittal growth evaluated on dry skulls from children and adolescents. 61
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Mutations of POLR3A encoding a catalytic subunit of RNA polymerase Pol III cause a recessive hypomyelinating leukodystrophy. 61
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Clinical and functional data implicate the Arg(151)Ser variant of MSX1 in familial hypodontia. 61
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Isolated oligodontia associated with mutations in EDARADD, AXIN2, MSX1, and PAX9 genes. 61
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Correlation between the phenotypes and genotypes of X-linked hypohidrotic ectodermal dysplasia and non-syndromic hypodontia caused by ectodysplasin-A mutations. 61
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Oral features in five adult patients with Wolf-Hirschhorn syndrome. 61
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Prevalence and distribution of selected developmental dental anomalies in an Indian population. 61
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Dental agenesis patterns of permanent teeth in Apert syndrome. 61
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Assessment of dental anomalies on panoramic radiographs: inter- and intraexaminer agreement. 61
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Endodontic management in oculo-facio-cardio-dental syndrome: a case report. 61
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Congenitally missing lateral incisors--a comparison between restorative, implant, and orthodontic approaches. 61
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Non-syndromic oligodontia with a novel mutation of PAX9. 61
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Genetic basis of non syndromic hypodontia: a DNA investigation performed on three couples of monozygotic twins about PAX9 mutation. 61
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Case report of oligodontia: long term stability of orthognatic surgery and prosthetic rehabilitation. 61
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Application of orthodontic mini-implants and ligation for absolute skeletal anchorage to the intraoral labiolingual appliance: midface distraction osteogenesis cases treated with the RED System. 61
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Prevalence and patterns of permanent tooth agenesis in Down syndrome and their association with craniofacial morphology. 61
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Eponym: Johanson-Blizzard syndrome. 61
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A whole-genome scan in a large family with leukodystrophy and oligodontia reveals linkage to 10q22. 61
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Survey of congenitally missing teeth in orthodontic patients in Eastern Bavaria. 61
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The genetic basis of craniofacial and dental abnormalities. 61
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Transcriptional regulation of MSX1 natural antisense transcript. 61
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Agenesis of permanent mandibular anterior teeth: a case report. 61
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Regulation of bmp4 expression in odontogenic mesenchyme: from simple to complex. 61
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A new hypo/oligodontia syndrome: Carvajal/Naxos syndrome secondary to desmoplakin-dominant mutations. 61
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Psoriatic triad in a patient presenting with oligodontia. 61
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Functional aspects of treatment with implant-supported single crowns: a quality control study in subjects with tooth agenesis. 61
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Functional analysis of Ectodysplasin-A mutations causing selective tooth agenesis. 61
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Tooth dimensions in hypodontia with a known PAX9 mutation. 54
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Tooth abnormalities and soft tissue alterations in patients with G/BBB syndrome. 61
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Polyneuropathy, scoliosis, tall stature, and oligodontia represent novel features of the interstitial 6p deletion phenotype. 61
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Studies of dental anomalies in a large group of school children. 61
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[Clinical examination of children with tooth aplasia. Correlations between dental symptoms and the whole organism]. 61
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Hypohidrotic ectodermal dysplasia. 61
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Mutations in the EDA gene are responsible for X-linked hypohidrotic ectodermal dysplasia and hypodontia in Chinese kindreds. 54
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Impacted primary tooth and tooth agenesis: a case report of monozygotic twins. 61
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Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts. 61
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Dental management of a patient with oculo-facio-cardio-dental syndrome. 61
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Evidence of linkage disequilibrium between polymorphisms at the IRF6 locus and isolate tooth agenesis, in a Turkish population. 61
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Tooth abnormalities and soft tissue changes in patients with velocardiofacial syndrome. 61
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The genetic basis of inherited anomalies of the teeth. Part 1: clinical and molecular aspects of non-syndromic dental disorders. 61
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Dental anomalies as part of the cleft spectrum. 61
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Johanson-Blizzard syndrome: report of a novel mutation and severe liver involvement. 61
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Tooth agenesis: from molecular genetics to molecular dentistry. 61
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Can persistence of primary molars be predicted in subjects with multiple tooth agenesis? 61
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Non-syndromic tooth agenesis in two Chinese families associated with novel missense mutations in the TNF domain of EDA (ectodysplasin A). 61
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A genome wide linkage scan for cleft lip and palate and dental anomalies. 61
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An orthopantomographic study of hypodontia in permanent teeth of Japanese pediatric patients. 61
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Implant failure in young children with ectodermal dysplasia: a retrospective evaluation of use and outcome of dental implant treatment in children in Sweden. 61
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Assessing the proposed association between tooth agenesis and taurodontism in 975 paediatric subjects. 61
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PAX9 polymorphisms and susceptibility to sporadic tooth agenesis: a case-control study in southeast China. 61
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A new autosomal recessive syndrome of ocular colobomas, ichthyosis, brain malformations and endocrine abnormalities in an inbred Emirati family. 61
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Familial non-syndromic cleft lip and palate--analysis of the IRF6 gene and clinical phenotypes. 54
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Dental implants in the management of nonsyndromal oligodontia. 61
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Use of dental implants in the management of syndromal oligodontia. 61
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Treatment of a patient with oligodontia: a case report. 61
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Genotype-phenotype correlation in 21 patients with Wolf-Hirschhorn syndrome using high resolution array comparative genome hybridisation (CGH). 61
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[Establishment of electronic medical record of patients with tooth agenesis]. 61
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Treatment with removable prosthesis in hypohidrotic ectodermal dysplasia. A clinical case. 61
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Tooth agenesis in a family and homozygous PAX9 mutation in exon 3: a case report. 61
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When should we extract deciduous teeth and place implants in young individuals with tooth agenesis? 61
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A novel missense mutation in the EDA gene associated with X-linked recessive isolated hypodontia. 54
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Multidisciplinary Management of Oligodontia. 61
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Progressive symmetric erythro-keratosis associated with oligodontia, severe caries, disturbed hair growth and ectopic nail: a new syndrome? 61
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[Clinical analysis of simple hypodontia]. 61
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Biomechanical aspects of external root resorption in orthodontic therapy. 61
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Occipital atretic cephalocele, striking facial anomalies, and large feet in three siblings of a consanguineous union. 61
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Treatment of oligodontia with endo-osseous fixtures: experience in eight consecutive patients at the end of dental growth. 61
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Genes affecting tooth morphogenesis. 61
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Association between polymorphism in the promoter region (G/C-915) of PAX9 gene and third molar agenesis. 54
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Cranial suture biology and dental development: genetic and clinical perspectives. 54
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Quest for the cause of oligodontia in Suncus murinus (Soricomorpha, Soricidae): Morphological re-examination. 61
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Genes affecting tooth morphogenesis. 61
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Familial human hypodontia--is it all in the genes? 61
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Derivation of a mouse model for conditional inactivation of Pax9. 61
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Patterns of missing teeth in a population of oligodontia patients. 61
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The role of MSX1 in tooth agenesis in Iranians. 61
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Oligodontia and associated characteristics: assessment in view of prosthodontic rehabilitation. 61
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