HYD2
MCID: TTH011
MIFTS: 17

Tooth Agenesis, Selective, 2 (HYD2)

Categories: Genetic diseases, Oral diseases

Aliases & Classifications for Tooth Agenesis, Selective, 2

MalaCards integrated aliases for Tooth Agenesis, Selective, 2:

Name: Tooth Agenesis, Selective, 2 58 13 74
Hypodontia/oligodontia 2; Hyd2 58
Hypodontia/oligodontia 2 58
Sthag2 58
Hyd2 58

Classifications:



External Ids:

OMIM 58 602639
MedGen 43 C1865092
UMLS 74 C1865092

Summaries for Tooth Agenesis, Selective, 2

MalaCards based summary : Tooth Agenesis, Selective, 2, also known as hypodontia/oligodontia 2; hyd2, is related to perrault syndrome 1 and tooth agenesis. An important gene associated with Tooth Agenesis, Selective, 2 is HYD2 (Hypodontia 2 (Autosomal Recessive)). The drugs AT-101 and Nitric Oxide have been mentioned in the context of this disorder.

Description from OMIM: 602639

Related Diseases for Tooth Agenesis, Selective, 2

Diseases in the Tooth Agenesis, Selective, 1 family:

Tooth Agenesis, Selective, 4 Tooth Agenesis, Selective, 2
Tooth Agenesis, Selective, 3 Tooth Agenesis, Selective, 5
Tooth Agenesis, Selective, 7 Tooth Agenesis, Selective, 8
Tooth Agenesis, Selective, 9

Diseases related to Tooth Agenesis, Selective, 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 perrault syndrome 1 11.1
2 tooth agenesis 11.1

Symptoms & Phenotypes for Tooth Agenesis, Selective, 2

Clinical features from OMIM:

602639

Drugs & Therapeutics for Tooth Agenesis, Selective, 2

Drugs for Tooth Agenesis, Selective, 2 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
AT-101 Approved, Investigational Phase 1 90141-22-3, 652-67-5 12597
2
Nitric Oxide Approved Phase 1 10102-43-9 145068
3
Hydralazine Approved Phase 1 86-54-4 3637
4
Isosorbide Dinitrate Approved, Investigational Phase 1 87-33-2 6883
5 Vasodilator Agents Phase 1
6 Natriuretic Agents Phase 1
7 Nitric Oxide Donors Phase 1
8 isosorbide-5-mononitrate Phase 1
9 Antihypertensive Agents Phase 1
10 diuretics Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Comparison of Various Combinations of BiDil Capsules and BiDil Tablets in Healthy Human Volunteers Completed NCT01587313 Phase 1 Isosorbide dinitrate / hydralazine capsules

Search NIH Clinical Center for Tooth Agenesis, Selective, 2

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Anatomical Context for Tooth Agenesis, Selective, 2

Publications for Tooth Agenesis, Selective, 2

Variations for Tooth Agenesis, Selective, 2

Expression for Tooth Agenesis, Selective, 2

Search GEO for disease gene expression data for Tooth Agenesis, Selective, 2.

Pathways for Tooth Agenesis, Selective, 2

GO Terms for Tooth Agenesis, Selective, 2

Sources for Tooth Agenesis, Selective, 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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