HYD2
MCID: TTH011
MIFTS: 13

Tooth Agenesis, Selective, 2 (HYD2)

Categories: Genetic diseases, Oral diseases

Aliases & Classifications for Tooth Agenesis, Selective, 2

MalaCards integrated aliases for Tooth Agenesis, Selective, 2:

Name: Tooth Agenesis, Selective, 2 57 13 73
Hypodontia/oligodontia 2; Hyd2 57
Hypodontia/oligodontia 2 57
Sthag2 57
Hyd2 57

Classifications:



External Ids:

OMIM 57 602639
MedGen 42 C1865092
UMLS 73 C1865092

Summaries for Tooth Agenesis, Selective, 2

MalaCards based summary : Tooth Agenesis, Selective, 2, also known as hypodontia/oligodontia 2; hyd2, is related to perrault syndrome 1 and tooth agenesis. An important gene associated with Tooth Agenesis, Selective, 2 is HYD2 (Hypodontia 2 (Autosomal Recessive)). The drugs Hydralazine and AT-101 have been mentioned in the context of this disorder.

Description from OMIM: 602639

Related Diseases for Tooth Agenesis, Selective, 2

Diseases in the Tooth Agenesis, Selective, 1 family:

Tooth Agenesis, Selective, 4 Tooth Agenesis, Selective, 2
Tooth Agenesis, Selective, 3 Tooth Agenesis, Selective, 5
Tooth Agenesis, Selective, 7 Tooth Agenesis, Selective, 8
Tooth Agenesis, Selective, 9

Diseases related to Tooth Agenesis, Selective, 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 perrault syndrome 1 11.1
2 tooth agenesis 11.1

Symptoms & Phenotypes for Tooth Agenesis, Selective, 2

Clinical features from OMIM:

602639

Drugs & Therapeutics for Tooth Agenesis, Selective, 2

Drugs for Tooth Agenesis, Selective, 2 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hydralazine Approved Phase 1 86-54-4 3637
2
AT-101 Approved, Investigational Phase 1 90141-22-3, 652-67-5 12597
3
Nitric Oxide Approved Phase 1 10102-43-9 145068
4
Isosorbide Dinitrate Approved, Investigational Phase 1 87-33-2 6883
5 Nitric Oxide Donors Phase 1
6 isosorbide-5-mononitrate Phase 1
7 Natriuretic Agents Phase 1
8 Antihypertensive Agents Phase 1
9 diuretics Phase 1
10 Vasodilator Agents Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Comparison of Various Combinations of BiDil Capsules and BiDil Tablets in Healthy Human Volunteers Completed NCT01587313 Phase 1 Isosorbide dinitrate / hydralazine capsules

Search NIH Clinical Center for Tooth Agenesis, Selective, 2

Genetic Tests for Tooth Agenesis, Selective, 2

Anatomical Context for Tooth Agenesis, Selective, 2

Publications for Tooth Agenesis, Selective, 2

Variations for Tooth Agenesis, Selective, 2

Expression for Tooth Agenesis, Selective, 2

Search GEO for disease gene expression data for Tooth Agenesis, Selective, 2.

Pathways for Tooth Agenesis, Selective, 2

GO Terms for Tooth Agenesis, Selective, 2

Sources for Tooth Agenesis, Selective, 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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