Aliases & Classifications for Tooth Size

MalaCards integrated aliases for Tooth Size:

Name: Tooth Size 58

Characteristics:

OMIM:

58
Inheritance:
x-linked
also a y chromosome locus


HPO:

33
tooth size:
Inheritance x-linked inheritance


External Ids:

OMIM 58 314240
MedGen 43 C1839140
SNOMED-CT via HPO 70 263934009 422775003

Summaries for Tooth Size

MalaCards based summary : Tooth Size is related to cleft lip and cleft lip/palate. An important gene associated with Tooth Size is PAX9 (Paired Box 9), and among its related pathways/superpathways are Pathways in cancer and Mesodermal Commitment Pathway. The drugs tannic acid and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and kidney, and related phenotypes are abnormality of the dentition and Synthetic lethal with vaccinia virus (VACV) infection

Description from OMIM: 314240

Related Diseases for Tooth Size

Diseases related to Tooth Size via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 33)
# Related Disease Score Top Affiliating Genes
1 cleft lip 29.6 BMP4 MSX1 PAX9
2 cleft lip/palate 29.6 BMP4 MSX1
3 cleft palate, isolated 29.0 BMP4 MSX1 PAX9
4 septopreoptic holoprosencephaly 9.9 FGF8 SHH
5 holoprosencephaly 9.9 FGF8 SHH
6 midline interhemispheric variant of holoprosencephaly 9.9 FGF8 SHH
7 alobar holoprosencephaly 9.9 FGF8 SHH
8 lobar holoprosencephaly 9.9 FGF8 SHH
9 teeth, supernumerary 9.9
10 gingival recession 9.9
11 47,xyy 9.9
12 47, xxy 9.9
13 microform holoprosencephaly 9.9 FGF8 SHH
14 anodontia 9.9 MSX1 PAX9
15 semilobar holoprosencephaly 9.9 FGF8 SHH
16 focal epithelial hyperplasia 9.9 FGF8 SHH
17 hypothyroidism, thyroidal or athyroidal, with spiky hair and cleft palate 9.8 MSX1 SHH
18 ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive 9.7 MSX1 PAX9
19 hemifacial microsomia 9.7
20 schizophrenia 9.7
21 down syndrome 9.7
22 turner syndrome 9.7
23 sleep disorder 9.7
24 neuroendocrine neoplasm of appendix 9.7
25 axenfeld-rieger syndrome, type 1 9.7 BMP4 FGF8 SHH
26 orofacial cleft 9.6 BMP4 MSX1
27 fibular aplasia or hypoplasia, femoral bowing and poly-, syn-, and oligodactyly 9.6 MSX1 PAX9 SHH
28 tooth agenesis 9.6 BMP4 MSX1 PAX9
29 mouth disease 9.5 MSX1 PAX9
30 syngnathia 9.5 BMP4 FGF8 MSX1
31 cleft palate with or without ankyloglossia, x-linked 9.5 BMP4 FGF8 MSX1
32 agnathia-otocephaly complex 9.2 BMP4 FGF8 MSX1 SHH
33 physical disorder 9.2 BMP4 FGF8 MSX1 SHH

Graphical network of the top 20 diseases related to Tooth Size:



Diseases related to Tooth Size

Symptoms & Phenotypes for Tooth Size

Human phenotypes related to Tooth Size:

33
# Description HPO Frequency HPO Source Accession
1 abnormality of the dentition 33 HP:0000164

Symptoms via clinical synopsis from OMIM:

58
Teeth:
tooth size

Clinical features from OMIM:

314240

GenomeRNAi Phenotypes related to Tooth Size according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with vaccinia virus (VACV) infection GR00362-A 8.8 BMP4 MSX1 PAX9

MGI Mouse Phenotypes related to Tooth Size:

47 (show all 15)
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.95 BMP4 FGF8 MSX1 PAX9 SHH
2 craniofacial MP:0005382 9.93 BMP4 FGF8 MSX1 PAX9 SHH
3 digestive/alimentary MP:0005381 9.92 BMP4 FGF8 MSX1 PAX9 SHH
4 embryo MP:0005380 9.91 BMP4 FGF8 MSX1 PAX9 SHH
5 endocrine/exocrine gland MP:0005379 9.89 BMP4 FGF8 MSX1 PAX9 SHH
6 growth/size/body region MP:0005378 9.88 BMP4 FGF8 MSX1 PAX9 SHH
7 hearing/vestibular/ear MP:0005377 9.85 BMP4 FGF8 MSX1 PAX9 SHH
8 limbs/digits/tail MP:0005371 9.83 BMP4 FGF8 MSX1 PAX9 SHH
9 mortality/aging MP:0010768 9.8 BMP4 FGF8 MSX1 PAX9 SHH
10 muscle MP:0005369 9.77 BMP4 FGF8 MSX1 PAX9 SHH
11 normal MP:0002873 9.72 BMP4 FGF8 MSX1 PAX9 SHH
12 reproductive system MP:0005389 9.56 BMP4 FGF8 PAX9 SHH
13 respiratory system MP:0005388 9.55 BMP4 FGF8 MSX1 PAX9 SHH
14 skeleton MP:0005390 9.35 BMP4 FGF8 MSX1 PAX9 SHH
15 vision/eye MP:0005391 8.92 BMP4 FGF8 MSX1 SHH

Drugs & Therapeutics for Tooth Size

Drugs for Tooth Size (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 171)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
tannic acid Approved Phase 4,Phase 2,Phase 3,Not Applicable 1401-55-4
2
Benzocaine Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 94-09-7, 1994-09-7 2337
3
Metformin Approved Phase 4,Not Applicable 657-24-9 14219 4091
4
Anastrozole Approved, Investigational Phase 4,Phase 3,Phase 2 120511-73-1 2187
5
Letrozole Approved, Investigational Phase 4,Phase 3 112809-51-5 3902
6
Caffeine Approved Phase 4 58-08-2 2519
7
Mecasermin Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 68562-41-4
8 Poractant alfa Approved Phase 4 129069-19-8
9
Acetaminophen Approved Phase 4 103-90-2 1983
10 Deslorelin Investigational, Vet_approved Phase 4,Phase 2 57773-65-6
11 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
12 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
13 Imatinib Mesylate Phase 4 220127-57-1 123596
14 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
15 Hypoglycemic Agents Phase 4,Phase 2,Phase 3,Not Applicable
16 Insulin, Globin Zinc Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
17 insulin Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
18 Estrogens Phase 4,Phase 3,Phase 2
19 Contraceptive Agents Phase 4,Phase 3
20 Coagulants Phase 4,Phase 3
21 Factor VIII Phase 4,Phase 3,Not Applicable
22 Hemostatics Phase 4,Phase 3
23 HIV Protease Inhibitors Phase 4
24 Sitagliptin Phosphate Phase 4
25
protease inhibitors Phase 4
26 Dipeptidyl-Peptidase IV Inhibitors Phase 4
27 Incretins Phase 4
28 Biguanides Phase 4
29 Steroid Synthesis Inhibitors Phase 4,Phase 3,Phase 2
30 Aromatase Inhibitors Phase 4,Phase 3,Phase 2
31 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2
32 Estrogen Antagonists Phase 4,Phase 3,Phase 2
33 Estrogen Receptor Antagonists Phase 4,Phase 3,Phase 2
34 Respiratory System Agents Phase 4,Phase 2
35 Analgesics Phase 4,Not Applicable
36 Central Nervous System Stimulants Phase 4
37 Neurotransmitter Agents Phase 4,Phase 2
38 Phosphodiesterase Inhibitors Phase 4,Phase 2
39 Purinergic P1 Receptor Antagonists Phase 4,Phase 2
40 Peripheral Nervous System Agents Phase 4,Phase 2,Not Applicable
41 Mitogens Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
42 Luteolytic Agents Phase 4
43 Triptorelin Pamoate Phase 4
44 Pulmonary Surfactants Phase 4
45 Antipyretics Phase 4
46 Analgesics, Non-Narcotic Phase 4
47
Zinc Approved, Investigational Phase 2, Phase 3,Phase 3,Not Applicable 7440-66-6 32051
48
Estradiol Approved, Investigational, Vet_approved Phase 3 50-28-2 5757
49
Polyestradiol phosphate Approved Phase 3 28014-46-2
50
Ivacaftor Approved Phase 3,Phase 2 873054-44-5 16220172

Interventional clinical trials:

(show top 50) (show all 196)
# Name Status NCT ID Phase Drugs
1 Assessment Of Gh-Igf-1 Axis In Children With Chronic Myelogenous Leukemia (CML) In Remission Unknown status NCT01901666 Phase 4 Growth Hormone
2 Clinical Study of Pegylated Somatropin to Treat Children Growth Hormone Deficiency Unknown status NCT02908958 Phase 4
3 Short Stature Related Distress Completed NCT01246219 Phase 4 GH treatment (Genotropin);1 year treatment with placebo followed by optional 3 years of GH treatment
4 Biochemical Markers of Growth Response to Growth Hormone Treatment in Children With Idiopathic Short Stature Completed NCT00458263 Phase 4 Somatotropin growth hormone recombinant human
5 Growth Hormone Treatment for the Prevention of Short Stature in Young Girls With Turner Syndrome Before the Age of 4 Years Completed NCT01066052 Phase 4 r-hGH
6 Long Term Study of Genotropin (Somatropin) for Short Children Born Small for Gestational Age (SGA) Completed NCT01859949 Phase 4 Genotropin (somatropin)
7 Long Term Effect of Somatropin in Subjects With Intrauterine Growth Retardation Completed NCT01734447 Phase 4 somatropin;somatropin;somatropin
8 Endocrine Dysfunction and Growth Hormone Deficiency in Children With Optic Nerve Hypoplasia Completed NCT00140413 Phase 4 Nutropin AQ
9 Growth Hormone and Endothelial Function in Children Completed NCT00373386 Phase 4 growth hormone
10 A Study to Optimize Growth Hormone Dosing in Children With Chronic Kidney Disease by Measuring IGF-1 Levels in Blood Completed NCT00212758 Phase 4 Nutropin AQ
11 Evaluation of the Ease of Use, Preference, and Safety of EutropinPen Inj. Completed NCT03015909 Phase 4 Somatropin
12 Phase 3/4 Study of a Recombinant Protein-Free Factor VIII (rAHF-PFM): Comparison of Continuous Infusion Versus Intermittent Bolus Infusion in Hemophilia A Subjects Undergoing Major Orthopedic Surgery Completed NCT00357656 Phase 4 Recombinant Protein-Free Factor VIII (rAHF-PFM);Recombinant Protein-Free Factor VIII (rAHF-PFM)
13 Sitagliptin + Metformin Compared to Metformin Monotherapy and Placebo in Women With a Recent GDM Completed NCT01856907 Phase 4 Sitagliptin-Metformin;Metformin;Placebo pill
14 Aromatase Inhibitor Growth Study: Letrozole vs. Anastrozole Recruiting NCT02137538 Phase 4 Letrozole;Anastrozole
15 Extension Study of Pegylated Somatropin to Treat Growth Retardation Caused by Endogenous Growth Hormone Deficiency in Children Recruiting NCT03290235 Phase 4 PEG-somatropin
16 A 4 Year Combination Therapy of Growth Hormone and (GnRH) Agonist in Children With a Short Predicted Height Active, not recruiting NCT00840944 Phase 4 somatropin;triptorelin
17 Exogenous Surfactant in Very Preterm Neonates in Prevention of Bronchopulmonary Dysplasia Active, not recruiting NCT01039285 Phase 4 Curosurf
18 Exploratory Study to Investigate Cognition Function and Mobility in Individuals With Pain Terminated NCT02974114 Phase 4 Paracetamol and caffeine;Paracetamol
19 Predictive Value of the Insulin-like Growth Factor-1 (IGF-1) Generation Test for the Growth Response to Growth Hormone Treatment (PRED-IGF) Withdrawn NCT01438801 Phase 4 Nutropin [Somatropin (rDNA origin) for injection]
20 Individualized, Target-Driven Treatment Of Children With Idiopathic Short Stature Completed NCT00396097 Phase 3 Genotropin;Genotropin
21 Somatropin + Leuprorelin vs Somatropin Alone in Pubertal Children With Idiopathic Short Stature Completed NCT00355030 Phase 3 somatropin;leuprorelin
22 Aromatase Inhibitors, Alone And In Combination With Growth Hormone In Adolescent Boys With Idiopathic Short Stature Completed NCT01248416 Phase 3 Aromatase Inhibitor;Growth Hormone;Aromatase Inhibitor and Growth Hormone
23 Efficacy and Safety of Recombinant Human Growth Hormone on Height Velocity in Subjects With Idiopathic Short Stature Completed NCT01778023 Phase 3 somatropin
24 A Phase 3 Study to Evaluate the Safety and Efficacy of Saizen® in Children With Idiopathic Short Stature (ISS) Completed NCT01746862 Phase 3 Saizen®;Saizen®
25 Efficacy and Safety of DA-3002 in Children With Idiopathic Short Stature Completed NCT01786902 Phase 3 DA-3002
26 Investigating the Long-term Efficacy and Safety of Two Doses of NN-220 (Somatropin) in Short Stature Due to Noonan Syndrome Completed NCT01927861 Phase 3 somatropin
27 Weekly Zinc Chelate Supplementation on Children's Growth Completed NCT01911260 Phase 2, Phase 3
28 Amendment (g) Unblinded Extension Phase of Somatropin in Patients With Idiopathic Short Stature Completed NCT00191074 Phase 3 somatropin, rDNA origin, for injection
29 Recombinant Human Insulin-Like Growth Factor (rhIGF-1) Treatment of Short Stature Associated With IGF-1 Deficiency Completed NCT00125190 Phase 2, Phase 3 rhIGF-1 (mecasermin) for a period of 86 weeks
30 Treatment With Recombinant Human Growth Hormone Genotonorm (Registered) In Children With Short Stature Secondary Completed NCT00174278 Phase 3 Somatropin
31 Efficacy and Safety of Intravenous and Subcutaneous Secukinumab in Moderate to Severe Chronic Plaque-type Psoriasis Completed NCT01412944 Phase 3 secukinumab 150mg;secukinumab 10mg/kg i.v. regimen
32 Individualizing Dose of Growth Hormone to Maintain Normal Growth Velocity After Fulfilled Catch up Growth in Children Completed NCT02879747 Phase 2, Phase 3 Genotropin
33 Effect of Growth Hormone in Children With Growth Hormone Deficiency Completed NCT00262249 Phase 3 somatropin
34 Treatment Of Short Stature With Genotropin In Children Born Small For Gestational Age Until Final Height Completed NCT00174421 Phase 3 Treatment with Genotropin in different dosages
35 Treatment Of Children With Short Stature At An Age Of 3-7 Years Who Were Born Small For Gestational Age Completed NCT00174408 Phase 3 Genotropin
36 Somatropin Treatment in Patients With SHOX Deficiency and Turner Syndrome Completed NCT00190658 Phase 3 Somatropin (rDNA origin) for injection
37 Long-Term Treatment With rhIGF-1 in GHIS Completed NCT00571727 Phase 2, Phase 3 mecasermin
38 A Prebiotic Agave Derivated Metlin & Metlos in Infant Formula Completed NCT01251783 Phase 3
39 Growth Hormone Treatment in Children Born Small for Gestational Age (SGA) Completed NCT00184717 Phase 3 somatropin;somatropin
40 Genotropin Study Assessing Use of Injection Pen Completed NCT00965484 Phase 3
41 Genotropin Treatment in Short Prepubertal Children With Intra-Uterine Growth Retardation Completed NCT01073605 Phase 3 Genotonorm;Genotonorm;Genotonorm
42 Prepubertal Children With Growth Failure Associated With Primary Insulin-Like Growth Factor-1 (IGF-1) Deficiency Completed NCT00125164 Phase 3 rhIGF-1 (mecasermin, Tercica, Inc.)
43 Saizen in Intra-uterine Growth Retardation Completed NCT01400698 Phase 3 Saizen® A;Saizen® B
44 Growth Hormone Therapy in Osteogenesis Imperfecta Completed NCT00001305 Phase 3 Humatrope
45 A Clinical Study to Assess the Efficacy and Safety of DA-3002 Completed NCT01813630 Phase 3 DA-3002;Genotropin®
46 Study of Ivacaftor in Cystic Fibrosis Subjects 2 Through 5 Years of Age With a CFTR Gating Mutation Completed NCT01705145 Phase 3 Ivacaftor
47 Three Times Weekly (TIW) Growth Hormone Therapy in Children on Hemodialysis Completed NCT00943995 Phase 3 somatropin
48 Roll-Over Study of Ivacaftor in Cystic Fibrosis Pediatric Subjects With a CF Transmembrane Conductance Regulator Gene (CFTR) Gating Mutation Completed NCT01946412 Phase 3 Ivacaftor
49 Safety and Pharmacokinetic Study of Lumacaftor/Ivacaftor in Subjects Aged 2 Through 5 Years With Cystic Fibrosis, Homozygous for F508del Completed NCT02797132 Phase 3 LUM/IVA
50 Arimidex Multicenter Trial in Growth Hormone (GH) Deficient Boys Completed NCT00133354 Phase 2, Phase 3 Arimidex (Anastrozole);Placebo;Growth Hormone

Search NIH Clinical Center for Tooth Size

Genetic Tests for Tooth Size

Anatomical Context for Tooth Size

MalaCards organs/tissues related to Tooth Size:

42
Bone, Testes, Kidney, Endothelial, Skeletal Muscle, Thyroid, Brain

Publications for Tooth Size

Articles related to Tooth Size:

(show top 50) (show all 295)
# Title Authors Year
1
Dental arch dimensions, form and tooth size ratio among a Saudi sample. ( 29332114 )
2018
2
Space conditions, palatal vault height, and tooth size in patients with and without palatally displaced canines: A prospective cohort study. ( 30102088 )
2018
3
A Comparative Analysis of Tooth Size Discrepancy between Male and Female Subjects Presenting with a Class I Malocclusion. ( 30104915 )
2018
4
Overall and Anterior Tooth Size Ratios in a Group of Emiratis. ( 30369975 )
2018
5
Correlation between tooth size-arch length discrepancy and interradicular distances measured on CBCT and panoramic radiograph: an evaluation for miniscrew insertion. ( 30427499 )
2018
6
Dental occlusion analysis in the Mesolithic-Neolithic Age, Bronze Age, and Roman to Medieval times in Serbia: Tooth size comparison in skeletal samples. ( 28167335 )
2017
7
Prediction of Un-erupted Canine and Premolar Tooth Size in Mixed Dentition among Bangladeshi Population. ( 29208869 )
2017
8
Bolton tooth size ratio among qatari population sample: An odontometric study. ( 28197399 )
2017
9
The impact of premature birth on the permanent tooth size of incisors and first molars. ( 28371880 )
2017
10
Relative tooth size at birth in primates: Life history correlates. ( 28832934 )
2017
11
Heritability and genetic integration of tooth size in the South Carolina Gullah. ( 28832922 )
2017
12
Primary tooth size asymmetry in twins and singletons. ( 26898820 )
2016
13
A simple rule governs the evolution and development of hominin tooth size. ( 26911784 )
2016
14
The apportionment of tooth size and its implications in Australopithecus sediba versus other Plio-pleistocene and recent African hominins. ( 27402184 )
2016
15
Maxillary lateral incisor agenesis and its relationship to overall tooth size. ( 26460168 )
2016
16
Intermaxillary tooth size discrepancy in a Pakistani population: A stereomicroscope versus digital caliper. ( 27095892 )
2016
17
Simplifying optimal tooth-size calculations and communications between practitioners. ( 27894526 )
2016
18
Effects of PAX9 and MSX1 gene variants to hypodontia, tooth size and the type of congenitally missing teeth. ( 28040065 )
2016
19
Tooth-Size Discrepancies in Patients Requiring Mandibular Advancement Surgery. ( 27616536 )
2016
20
Tooth Size in Patients with Mild, Moderate and Severe Hypodontia and a Control Group. ( 27583048 )
2016
21
Outcome of premolar extractions on Bolton's overall ratio and tooth size discrepancies in South India. ( 27583218 )
2016
22
Management of Tooth Size Arch Size Discrepancy (TSASD) in Patients with Sleep Disorder Breathing. ( 29799696 )
2016
23
Evaluation and Comparison of Intermaxillary Tooth Size Discrepancy among Class I, Class II Division 1, and Class III Subjects Using Bolton's Analysis: An in vitro Study. ( 26435619 )
2015
24
Tooth Size Variation in Pinniped Dentitions. ( 26317362 )
2015
25
The Overbite Complexity: How The Vertical Position, Tooth-Size Ratios And Other Factors Affect Occlusion and Overbites. ( 26349293 )
2015
26
Hedgehog signaling regulates dental papilla formation and tooth size during zebrafish odontogenesis. ( 25645398 )
2015
27
Association between tooth size and interarch relationships in children with operated complete unilateral cleft lip and palate. ( 26061984 )
2015
28
Tooth size in Chinese Oroqen ethnic minority of Inner Mongolia Autonomous Region. ( 24996929 )
2015
29
Effect of intermaxillary tooth-size discrepancy on accuracy of prediction equations for mixed dentition space analysis. ( 25373496 )
2015
30
Tooth size discrepancy in a Libyan population, a cross-sectional study in schoolchildren. ( 25810819 )
2015
31
Is arch form influenced by sagittal molar relationship or Bolton tooth-size discrepancy? ( 26113007 )
2015
32
The relationship between tooth size discrepancy and archform classification in orthodontic patients. ( 26155344 )
2015
33
Incidence of Tooth Size Discrepancy in Different Groups of Malocclusion and its Relation to Extraction. ( 26225105 )
2015
34
Bolton tooth size ratio among Sudanese Population sample: A preliminary study. ( 26229948 )
2015
35
Tooth size discrepancies in Class II division 1 and Class III malocclusion requiring surgical-orthodontic or orthodontic treatment. ( 24526719 )
2014
36
On the relationships of postcanine tooth size with dietary quality and brain volume in primates: implications for hominin evolution. ( 24592388 )
2014
37
Sex determination by tooth size in a sample of Greek population. ( 24938541 )
2014
38
Interarch tooth size relationship of Indian population: does Bolton's analysis apply? ( 24939274 )
2014
39
Is there a relationship between increased tooth number and increased tooth size? A case report. ( 25195487 )
2014
40
Bolton tooth size ratio and its relation with arch widths, arch length and arch perimeter: a cone beam computed tomography (CBCT) study. ( 25220521 )
2014
41
Tooth-size discrepancy: a comparison between manual and digital methods. ( 25279529 )
2014
42
Estimation of Tooth Size Discrepancies among Different Malocclusion Groups. ( 25356005 )
2014
43
Generational differences in tooth size in the Japanese population: analysis of cohorts with a generation gap of four to five decades. ( 25895239 )
2014
44
Mesiodistal tooth size in non-syndromic unilateral cleft lip and palate patients: a meta-analysis. ( 23011523 )
2013
45
Evaluation of tooth size in patients with congenitally-missing teeth. ( 23487169 )
2013
46
Overjet, overbite and dental midline shift as predictors of tooth size discrepancy in a Bangladeshi population and a graphical overview of global tooth size ratios. ( 23530813 )
2013
47
Predicting tooth-size discrepancy: A new formula utilizing revised landmarks and 3-dimensional laser scanning technology. ( 23561420 )
2013
48
Mesiodistal crown diameters and tooth size discrepancy of permanent dentition in thalassemic patients. ( 24455089 )
2013
49
Comparison of Bolton analysis and tooth size measurements obtained using conventional and three-dimensional orthodontic models. ( 24966731 )
2013
50
Effects of premolar extractions on Bolton overall ratios and tooth-size discrepancies in a north Indian population. ( 24987639 )
2013

Variations for Tooth Size

Expression for Tooth Size

Search GEO for disease gene expression data for Tooth Size.

Pathways for Tooth Size

GO Terms for Tooth Size

Biological processes related to Tooth Size according to GeneCards Suite gene sharing:

(show top 50) (show all 73)
# Name GO ID Score Top Affiliating Genes
1 multicellular organism development GO:0007275 9.95 BMP4 FGF8 MSX1 PAX9 SHH
2 negative regulation of apoptotic process GO:0043066 9.94 BMP4 FGF8 MSX1 SHH
3 negative regulation of transcription, DNA-templated GO:0045892 9.92 BMP4 MSX1 PAX9
4 positive regulation of cell proliferation GO:0008284 9.92 BMP4 FGF8 SHH
5 regulation of signaling receptor activity GO:0010469 9.91 BMP4 FGF8 SHH
6 positive regulation of gene expression GO:0010628 9.9 BMP4 FGF8 SHH
7 kidney development GO:0001822 9.81 BMP4 FGF8 SHH
8 lung development GO:0030324 9.78 BMP4 FGF8 SHH
9 BMP signaling pathway GO:0030509 9.76 BMP4 FGF8 MSX1
10 anterior/posterior pattern specification GO:0009952 9.75 MSX1 SHH
11 cartilage development GO:0051216 9.74 BMP4 MSX1
12 canonical Wnt signaling pathway GO:0060070 9.74 FGF8 SHH
13 determination of left/right symmetry GO:0007368 9.74 FGF8 SHH
14 camera-type eye development GO:0043010 9.74 BMP4 SHH
15 roof of mouth development GO:0060021 9.74 MSX1 SHH
16 smoothened signaling pathway GO:0007224 9.74 BMP4 SHH
17 cell development GO:0048468 9.73 BMP4 SHH
18 heart looping GO:0001947 9.73 FGF8 SHH
19 cellular response to growth factor stimulus GO:0071363 9.73 BMP4 PAX9
20 bone development GO:0060348 9.73 BMP4 FGF8
21 forebrain development GO:0030900 9.73 BMP4 MSX1 SHH
22 heart development GO:0007507 9.73 BMP4 FGF8 MSX1 SHH
23 outflow tract morphogenesis GO:0003151 9.72 BMP4 FGF8
24 heart morphogenesis GO:0003007 9.72 FGF8 MSX1
25 positive chemotaxis GO:0050918 9.72 BMP4 FGF8
26 positive regulation of cell division GO:0051781 9.72 FGF8 SHH
27 embryonic skeletal system development GO:0048706 9.72 BMP4 SHH
28 midbrain development GO:0030901 9.71 MSX1 SHH
29 positive regulation of BMP signaling pathway GO:0030513 9.71 BMP4 MSX1
30 embryonic forelimb morphogenesis GO:0035115 9.71 MSX1 SHH
31 face morphogenesis GO:0060325 9.71 MSX1 PAX9
32 cell fate commitment GO:0045165 9.71 BMP4 FGF8 SHH
33 endoderm development GO:0007492 9.7 BMP4 PAX9
34 neuron fate commitment GO:0048663 9.7 BMP4 SHH
35 pituitary gland development GO:0021983 9.7 BMP4 MSX1
36 telencephalon development GO:0021537 9.7 BMP4 FGF8
37 embryonic digit morphogenesis GO:0042733 9.7 BMP4 MSX1 SHH
38 branching involved in blood vessel morphogenesis GO:0001569 9.69 FGF8 SHH
39 outflow tract septum morphogenesis GO:0003148 9.69 BMP4 FGF8
40 branching morphogenesis of an epithelial tube GO:0048754 9.69 BMP4 SHH
41 odontogenesis of dentin-containing tooth GO:0042475 9.69 BMP4 MSX1 SHH
42 vasculature development GO:0001944 9.68 BMP4 SHH
43 thyroid gland development GO:0030878 9.68 FGF8 SHH
44 anatomical structure formation involved in morphogenesis GO:0048646 9.68 BMP4 SHH
45 renal system development GO:0072001 9.68 BMP4 SHH
46 dopaminergic neuron differentiation GO:0071542 9.67 FGF8 SHH
47 signal transduction involved in regulation of gene expression GO:0023019 9.67 FGF8 MSX1
48 male genitalia development GO:0030539 9.67 FGF8 SHH
49 embryonic limb morphogenesis GO:0030326 9.67 BMP4 MSX1 SHH
50 epithelial tube branching involved in lung morphogenesis GO:0060441 9.66 BMP4 SHH

Molecular functions related to Tooth Size according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemoattractant activity GO:0042056 8.62 BMP4 FGF8

Sources for Tooth Size

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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