Aliases & Classifications for Tooth Size

MalaCards integrated aliases for Tooth Size:

Name: Tooth Size 57

Characteristics:

OMIM:

57
Inheritance:
x-linked
also a y chromosome locus


HPO:

32
tooth size:
Inheritance x-linked inheritance


External Ids:

OMIM 57 314240
MedGen 42 C1839140
SNOMED-CT via HPO 69 422775003 263934009

Summaries for Tooth Size

MalaCards based summary : Tooth Size is related to cleft lip and cleft lip/palate. An important gene associated with Tooth Size is PAX9 (Paired Box 9), and among its related pathways/superpathways are Pathways in cancer and Mesodermal Commitment Pathway. The drugs Benzocaine and Metformin have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and kidney, and related phenotypes are abnormality of the dentition and Synthetic lethal with vaccinia virus (VACV) infection

Description from OMIM: 314240

Related Diseases for Tooth Size

Graphical network of the top 20 diseases related to Tooth Size:



Diseases related to Tooth Size

Symptoms & Phenotypes for Tooth Size

Symptoms via clinical synopsis from OMIM:

57
Teeth:
tooth size


Clinical features from OMIM:

314240

Human phenotypes related to Tooth Size:

32
# Description HPO Frequency HPO Source Accession
1 abnormality of the dentition 32 HP:0000164

GenomeRNAi Phenotypes related to Tooth Size according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with vaccinia virus (VACV) infection GR00362-A 8.8 BMP4 MSX1 PAX9

MGI Mouse Phenotypes related to Tooth Size:

46 (show all 14)
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.93 BMP4 FGF8 MSX1 PAX9 SHH
2 craniofacial MP:0005382 9.92 BMP4 FGF8 MSX1 PAX9 SHH
3 digestive/alimentary MP:0005381 9.91 BMP4 FGF8 MSX1 PAX9 SHH
4 embryo MP:0005380 9.89 BMP4 FGF8 MSX1 PAX9 SHH
5 endocrine/exocrine gland MP:0005379 9.88 PAX9 SHH BMP4 FGF8 MSX1
6 growth/size/body region MP:0005378 9.85 BMP4 FGF8 MSX1 PAX9 SHH
7 hearing/vestibular/ear MP:0005377 9.83 BMP4 FGF8 MSX1 PAX9 SHH
8 limbs/digits/tail MP:0005371 9.8 BMP4 FGF8 MSX1 PAX9 SHH
9 muscle MP:0005369 9.77 BMP4 FGF8 MSX1 PAX9 SHH
10 normal MP:0002873 9.72 BMP4 FGF8 MSX1 PAX9 SHH
11 reproductive system MP:0005389 9.56 BMP4 FGF8 PAX9 SHH
12 respiratory system MP:0005388 9.55 BMP4 FGF8 MSX1 PAX9 SHH
13 skeleton MP:0005390 9.35 BMP4 FGF8 MSX1 PAX9 SHH
14 vision/eye MP:0005391 8.92 BMP4 FGF8 MSX1 SHH

Drugs & Therapeutics for Tooth Size

Drugs for Tooth Size (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 163)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzocaine Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 1994-09-7, 94-09-7 2337
2
Metformin Approved Phase 4,Not Applicable 657-24-9 14219 4091
3
Anastrozole Approved, Investigational Phase 4,Phase 3,Phase 2 120511-73-1 2187
4
Letrozole Approved, Investigational Phase 4,Phase 3 112809-51-5 3902
5 Poractant alfa Approved Phase 4 129069-19-8
6
Acetaminophen Approved Phase 4 103-90-2 1983
7 tannic acid Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Not Applicable
8
Caffeine Approved, Nutraceutical Phase 4 58-08-2 2519
9 Deslorelin Investigational, Vet_approved Phase 4,Phase 2 57773-65-6
10 Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
11 Hormones Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
12 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
13 Imatinib Mesylate Phase 4 220127-57-1 123596
14 Hypoglycemic Agents Phase 4,Phase 2,Phase 3,Not Applicable
15 insulin Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
16 Insulin, Globin Zinc Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
17 Estrogens Phase 4,Phase 3,Phase 2
18 Contraceptive Agents Phase 4,Phase 3
19 Coagulants Phase 4,Phase 3
20 Factor VIII Phase 4,Phase 3,Not Applicable
21 Hemostatics Phase 4,Phase 3
22 Dipeptidyl-Peptidase IV Inhibitors Phase 4
23 HIV Protease Inhibitors Phase 4
24 Incretins Phase 4
25
protease inhibitors Phase 4
26 Sitagliptin Phosphate Phase 4
27 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2
28 Aromatase Inhibitors Phase 4,Phase 3,Phase 2
29 Estrogen Antagonists Phase 4,Phase 3,Phase 2
30 Steroid Synthesis Inhibitors Phase 4,Phase 3,Phase 2
31 Respiratory System Agents Phase 4,Phase 2
32 Central Nervous System Stimulants Phase 4
33 Neurotransmitter Agents Phase 4,Phase 2
34 Peripheral Nervous System Agents Phase 4,Phase 2,Not Applicable
35 Phosphodiesterase Inhibitors Phase 4,Phase 2
36 Purinergic P1 Receptor Antagonists Phase 4,Phase 2
37 Mitogens Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
38 Analgesics Phase 4,Not Applicable
39 Luteolytic Agents Phase 4
40 Triptorelin Pamoate Phase 4
41 Pulmonary Surfactants Phase 4
42 Analgesics, Non-Narcotic Phase 4
43 Antipyretics Phase 4
44
Estradiol Approved, Investigational, Vet_approved Phase 3 50-28-2 5757
45 Estradiol valerate Approved, Investigational, Vet_approved Phase 3 979-32-8
46
Polyestradiol phosphate Approved Phase 3 28014-46-2
47
Zinc Approved, Investigational Phase 2, Phase 3,Phase 3,Not Applicable 7440-66-6 23994
48
Ethinyl Estradiol Approved Phase 3 57-63-6 5991
49
Medroxyprogesterone acetate Approved, Investigational Phase 3 71-58-9
50
Ergocalciferol Approved, Nutraceutical Phase 3 50-14-6 5280793

Interventional clinical trials:

(show top 50) (show all 186)
# Name Status NCT ID Phase Drugs
1 Assessment Of Gh-Igf-1 Axis In Children With Chronic Myelogenous Leukemia (CML) In Remission Unknown status NCT01901666 Phase 4 Growth Hormone
2 Short Stature Related Distress Completed NCT01246219 Phase 4 GH treatment (Genotropin);1 year treatment with placebo followed by optional 3 years of GH treatment
3 Biochemical Markers of Growth Response to Growth Hormone Treatment in Children With Idiopathic Short Stature Completed NCT00458263 Phase 4 Somatotropin growth hormone recombinant human
4 Growth Hormone Treatment for the Prevention of Short Stature in Young Girls With Turner Syndrome Before the Age of 4 Years Completed NCT01066052 Phase 4
5 Long Term Study of Genotropin (Somatropin) for Short Children Born Small for Gestational Age (SGA) Completed NCT01859949 Phase 4 Genotropin (somatropin)
6 Long Term Effect of Somatropin in Subjects With Intrauterine Growth Retardation Completed NCT01734447 Phase 4 somatropin;somatropin;somatropin
7 Endocrine Dysfunction and Growth Hormone Deficiency in Children With Optic Nerve Hypoplasia Completed NCT00140413 Phase 4 Nutropin AQ
8 Growth Hormone and Endothelial Function in Children Completed NCT00373386 Phase 4 growth hormone
9 A Study to Optimize Growth Hormone Dosing in Children With Chronic Kidney Disease by Measuring IGF-1 Levels in Blood Completed NCT00212758 Phase 4 Nutropin AQ
10 Phase 3/4 Study of a Recombinant Protein-Free Factor VIII (rAHF-PFM): Comparison of Continuous Infusion Versus Intermittent Bolus Infusion in Hemophilia A Subjects Undergoing Major Orthopedic Surgery Completed NCT00357656 Phase 4 Recombinant Protein-Free Factor VIII (rAHF-PFM);Recombinant Protein-Free Factor VIII (rAHF-PFM)
11 Sitagliptin + Metformin Compared to Metformin Monotherapy and Placebo in Women With a Recent GDM Completed NCT01856907 Phase 4 Sitagliptin-Metformin;Metformin;Placebo pill
12 Aromatase Inhibitor Growth Study: Letrozole vs. Anastrozole Recruiting NCT02137538 Phase 4 Letrozole;Anastrozole
13 Clinical Study of Pegylated Somatropin to Treat Children Growth Hormone Deficiency Recruiting NCT02908958 Phase 4
14 Extension Study of Pegylated Somatropin to Treat Growth Retardation Caused by Endogenous Growth Hormone Deficiency in Children Recruiting NCT03290235 Phase 4 PEG-somatropin
15 Evaluation of the Ease of Use, Preference, and Safety of EutropinPen Inj. Recruiting NCT03015909 Phase 4 Somatropin
16 A 4 Year Combination Therapy of Growth Hormone and (GnRH) Agonist in Children With a Short Predicted Height Active, not recruiting NCT00840944 Phase 4 somatropin;triptorelin
17 Exogenous Surfactant in Very Preterm Neonates in Prevention of Bronchopulmonary Dysplasia Active, not recruiting NCT01039285 Phase 4 Curosurf
18 Exploratory Study to Investigate Cognition Function and Mobility in Individuals With Pain Terminated NCT02974114 Phase 4 Paracetamol and caffeine;Paracetamol
19 Predictive Value of the Insulin-like Growth Factor-1 (IGF-1) Generation Test for the Growth Response to Growth Hormone Treatment (PRED-IGF) Withdrawn NCT01438801 Phase 4 Nutropin [Somatropin (rDNA origin) for injection]
20 The Role of Igf-1 Generation Test in Diagnosis and Treatment of Short Stature Unknown status NCT01970800 Phase 2, Phase 3 Growth Hormone
21 Individualized, Target-Driven Treatment Of Children With Idiopathic Short Stature Completed NCT00396097 Phase 3 Genotropin;Genotropin
22 Somatropin + Leuprorelin vs Somatropin Alone in Pubertal Children With Idiopathic Short Stature Completed NCT00355030 Phase 3 somatropin;leuprorelin
23 Aromatase Inhibitors, Alone And In Combination With Growth Hormone In Adolescent Boys With Idiopathic Short Stature Completed NCT01248416 Phase 3 Aromatase Inhibitor;Growth Hormone;Aromatase Inhibitor and Growth Hormone
24 Efficacy and Safety of Recombinant Human Growth Hormone on Height Velocity in Subjects With Idiopathic Short Stature Completed NCT01778023 Phase 3 somatropin
25 A Phase 3 Study to Evaluate the Safety and Efficacy of Saizen® in Children With Idiopathic Short Stature (ISS) Completed NCT01746862 Phase 3 Saizen®;Saizen®
26 Efficacy and Safety of DA-3002 in Children With Idiopathic Short Stature Completed NCT01786902 Phase 3 DA-3002
27 Weekly Zinc Chelate Supplementation on Children's Growth Completed NCT01911260 Phase 2, Phase 3
28 Amendment (g) Unblinded Extension Phase of Somatropin in Patients With Idiopathic Short Stature Completed NCT00191074 Phase 3 somatropin, rDNA origin, for injection
29 Recombinant Human Insulin-Like Growth Factor (rhIGF-1) Treatment of Short Stature Associated With IGF-1 Deficiency Completed NCT00125190 Phase 2, Phase 3 rhIGF-1 (mecasermin) for a period of 86 weeks
30 Treatment With Recombinant Human Growth Hormone Genotonorm (Registered) In Children With Short Stature Secondary Completed NCT00174278 Phase 3 Somatropin
31 Efficacy and Safety of Intravenous and Subcutaneous Secukinumab in Moderate to Severe Chronic Plaque-type Psoriasis Completed NCT01412944 Phase 3 secukinumab 150mg;secukinumab 10mg/kg i.v. regimen
32 Individualizing Dose of Growth Hormone to Maintain Normal Growth Velocity After Fulfilled Catch up Growth in Children Completed NCT02879747 Phase 2, Phase 3 Genotropin
33 Effect of Growth Hormone in Children With Growth Hormone Deficiency Completed NCT00262249 Phase 3 somatropin
34 Treatment Of Short Stature With Genotropin In Children Born Small For Gestational Age Until Final Height Completed NCT00174421 Phase 3 Treatment with Genotropin in different dosages
35 Treatment Of Children With Short Stature At An Age Of 3-7 Years Who Were Born Small For Gestational Age Completed NCT00174408 Phase 3 Genotropin
36 Somatropin Treatment in Patients With SHOX Deficiency and Turner Syndrome Completed NCT00190658 Phase 3 Somatropin (rDNA origin) for injection
37 Long-Term Treatment With rhIGF-1 in GHIS Completed NCT00571727 Phase 2, Phase 3 mecasermin
38 A Prebiotic Agave Derivated Metlin & Metlos in Infant Formula Completed NCT01251783 Phase 3
39 Growth Hormone Treatment in Children Born Small for Gestational Age (SGA) Completed NCT00184717 Phase 3 somatropin;somatropin
40 Genotropin Study Assessing Use of Injection Pen Completed NCT00965484 Phase 3
41 Genotropin Treatment in Short Prepubertal Children With Intra-Uterine Growth Retardation Completed NCT01073605 Phase 3 Genotonorm;Genotonorm;Genotonorm
42 Prepubertal Children With Growth Failure Associated With Primary Insulin-Like Growth Factor-1 (IGF-1) Deficiency Completed NCT00125164 Phase 3 rhIGF-1 (mecasermin, Tercica, Inc.)
43 Saizen in Intra-uterine Growth Retardation Completed NCT01400698 Phase 3 Saizen® A;Saizen® B
44 Growth Hormone Therapy in Osteogenesis Imperfecta Completed NCT00001305 Phase 3 Humatrope;Nutropin;GRH
45 Study of Ivacaftor in Cystic Fibrosis Subjects 2 Through 5 Years of Age With a CFTR Gating Mutation Completed NCT01705145 Phase 3 Ivacaftor
46 Three Times Weekly (TIW) Growth Hormone Therapy in Children on Hemodialysis Completed NCT00943995 Phase 3 somatropin
47 Roll-Over Study of Ivacaftor in Cystic Fibrosis Pediatric Subjects With a CF Transmembrane Conductance Regulator Gene (CFTR) Gating Mutation Completed NCT01946412 Phase 3 Ivacaftor
48 Arimidex Multicenter Trial in Growth Hormone (GH) Deficient Boys Completed NCT00133354 Phase 2, Phase 3 Arimidex (Anastrozole);Placebo;Growth Hormone
49 A Study of MK-0822 in Postmenopausal Women With Osteoporosis to Assess Fracture Risk (MK-0822-018) Completed NCT00529373 Phase 3 Odanacatib;Placebo for Odanacatib
50 Somatropin Treatment to Final Height in Turner Syndrome Completed NCT00191113 Phase 3 Somatropin;Ethinyl estradiol;Medroxyprogesterone acetate

Search NIH Clinical Center for Tooth Size

Genetic Tests for Tooth Size

Anatomical Context for Tooth Size

MalaCards organs/tissues related to Tooth Size:

41
Bone, Testes, Kidney, Endothelial, Liver, Skeletal Muscle, Thyroid

Publications for Tooth Size

Articles related to Tooth Size:

(show all 45)
# Title Authors Year
1
Dental arch dimensions, form and tooth size ratio among a Saudi sample. ( 29332114 )
2018
2
Dental occlusion analysis in the Mesolithic-Neolithic Age, Bronze Age, and Roman to Medieval times in Serbia: Tooth size comparison in skeletal samples. ( 28167335 )
2017
3
Prediction of Un-erupted Canine and Premolar Tooth Size in Mixed Dentition among Bangladeshi Population. ( 29208869 )
2017
4
Bolton tooth size ratio among qatari population sample: An odontometric study. ( 28197399 )
2017
5
The impact of premature birth on the permanent tooth size of incisors and first molars. ( 28371880 )
2017
6
Relative tooth size at birth in primates: Life history correlates. ( 28832934 )
2017
7
Heritability and genetic integration of tooth size in the South Carolina Gullah. ( 28832922 )
2017
8
Primary tooth size asymmetry in twins and singletons. ( 26898820 )
2016
9
A simple rule governs the evolution and development of hominin tooth size. ( 26911784 )
2016
10
The apportionment of tooth size and its implications in Australopithecus sediba versus other Plio-pleistocene and recent African hominins. ( 27402184 )
2016
11
Maxillary lateral incisor agenesis and its relationship to overall tooth size. ( 26460168 )
2016
12
Intermaxillary tooth size discrepancy in a Pakistani population: A stereomicroscope versus digital caliper. ( 27095892 )
2016
13
Simplifying optimal tooth-size calculations and communications between practitioners. ( 27894526 )
2016
14
Effects of PAX9 and MSX1 gene variants to hypodontia, tooth size and the type of congenitally missing teeth. ( 28040065 )
2016
15
Tooth-Size Discrepancies in Patients Requiring Mandibular Advancement Surgery. ( 27616536 )
2016
16
Tooth Size in Patients with Mild, Moderate and Severe Hypodontia and a Control Group. ( 27583048 )
2016
17
Outcome of premolar extractions on Bolton's overall ratio and tooth size discrepancies in South India. ( 27583218 )
2016
18
Management of Tooth Size Arch Size Discrepancy (TSASD) in Patients with Sleep Disorder Breathing. ( 29799696 )
2016
19
Evaluation and Comparison of Intermaxillary Tooth Size Discrepancy among Class I, Class II Division 1, and Class III Subjects Using Bolton's Analysis: An in vitro Study. ( 26435619 )
2015
20
Tooth Size Variation in Pinniped Dentitions. ( 26317362 )
2015
21
The Overbite Complexity: How The Vertical Position, Tooth-Size Ratios And Other Factors Affect Occlusion and Overbites. ( 26349293 )
2015
22
Hedgehog signaling regulates dental papilla formation and tooth size during zebrafish odontogenesis. ( 25645398 )
2015
23
Mesiodistal tooth size in non-syndromic unilateral cleft lip and palate patients: a meta-analysis. ( 23011523 )
2013
24
Association of common PAX9 variants with permanent tooth size variation in non-syndromic East Asian populations. ( 22810112 )
2012
25
Is gingival recession a consequence of an orthodontic tooth size and/or tooth position discrepancy? "A paradigm shift". ( 23738895 )
2011
26
Is gingival recession a consequence of an orthodontic tooth size and/or tooth position discrepancy? "A paradigm shift". ( 21462624 )
2011
27
Canine tooth size and fitness in male mandrills (Mandrillus sphinx). ( 18472142 )
2008
28
Tooth size and arch dimension in uncrowded versus crowded Class I malocclusions. ( 17351681 )
2007
29
Bolton tooth size discrepancies in skeletal Class I individuals presenting with different dental angle classifications. ( 16808571 )
2006
30
Evolution of genetically correlated traits: tooth size and body size in baboons. ( 16617432 )
2006
31
Individual variation in tooth-size/ arch-length changes from the primary to permanent dentitions. ( 16779973 )
2006
32
Dental arch space and permanent tooth size in the mixed dentition of a skeletal sample from the 14th to the 19th centuries and 3 contemporary samples. ( 12142897 )
2002
33
Tooth-size discrepancies among different occlusion groups of southern Chinese children. ( 11709674 )
2001
34
Secular trend in tooth size in urban Chinese assessed from two-generation family data. ( 11471129 )
2001
35
Inhibition of Wnt signaling by exogenous Mfrzb1 protein affects molar tooth size. ( 10831093 )
2000
36
Mesiodistal crown dimensions and tooth size discrepancy of the permanent dentition of Dominican Americans. ( 10961780 )
2000
37
An allometric perspective on primate postcanine tooth size. ( 2007503 )
1991
38
Sweat pore count, hair density and tooth size: heritability and genetic correlation. ( 3679235 )
1987
39
Postcanine tooth size in female primates. ( 3688209 )
1987
40
An example of a 46,XX infertile man and his permanent tooth sizes. ( 6140236 )
1983
41
Tooth size in children and young adults with trisomy 21 (Down) syndrome. ( 6223615 )
1983
42
Orthodontic-restorative treatment for relative mandibular anterior excess tooth-size problems. ( 6937140 )
1981
43
Family studies of tooth size factors in the permanent dentition. ( 443354 )
1979
44
Increase of tooth size in prehistoric coastal Peru, 10,000 B.P.-1,000 B.P. ( 375747 )
1979
45
The relationship of tooth size to body size in a population of rhesus monkeys (Macaca mulatta). ( 813527 )
1975

Variations for Tooth Size

Expression for Tooth Size

Search GEO for disease gene expression data for Tooth Size.

Pathways for Tooth Size

GO Terms for Tooth Size

Biological processes related to Tooth Size according to GeneCards Suite gene sharing:

(show top 50) (show all 73)
# Name GO ID Score Top Affiliating Genes
1 multicellular organism development GO:0007275 9.97 BMP4 FGF8 MSX1 PAX9 SHH
2 negative regulation of apoptotic process GO:0043066 9.94 BMP4 FGF8 MSX1 SHH
3 negative regulation of transcription, DNA-templated GO:0045892 9.92 BMP4 MSX1 PAX9
4 positive regulation of cell proliferation GO:0008284 9.92 BMP4 FGF8 SHH
5 regulation of signaling receptor activity GO:0010469 9.91 BMP4 FGF8 SHH
6 positive regulation of gene expression GO:0010628 9.9 BMP4 FGF8 SHH
7 kidney development GO:0001822 9.81 BMP4 FGF8 SHH
8 BMP signaling pathway GO:0030509 9.78 BMP4 FGF8 MSX1
9 lung development GO:0030324 9.77 BMP4 FGF8 SHH
10 anterior/posterior pattern specification GO:0009952 9.75 MSX1 SHH
11 canonical Wnt signaling pathway GO:0060070 9.75 FGF8 SHH
12 roof of mouth development GO:0060021 9.74 MSX1 SHH
13 determination of left/right symmetry GO:0007368 9.74 FGF8 SHH
14 cartilage development GO:0051216 9.74 BMP4 MSX1
15 smoothened signaling pathway GO:0007224 9.74 BMP4 SHH
16 camera-type eye development GO:0043010 9.74 BMP4 SHH
17 heart looping GO:0001947 9.73 FGF8 SHH
18 cell development GO:0048468 9.73 BMP4 SHH
19 bone development GO:0060348 9.73 BMP4 FGF8
20 cellular response to growth factor stimulus GO:0071363 9.73 BMP4 PAX9
21 outflow tract morphogenesis GO:0003151 9.73 BMP4 FGF8
22 heart development GO:0007507 9.73 BMP4 FGF8 MSX1 SHH
23 heart morphogenesis GO:0003007 9.72 FGF8 MSX1
24 positive regulation of cell division GO:0051781 9.72 FGF8 SHH
25 positive chemotaxis GO:0050918 9.72 BMP4 FGF8
26 embryonic skeletal system development GO:0048706 9.72 BMP4 SHH
27 forebrain development GO:0030900 9.72 BMP4 MSX1 SHH
28 midbrain development GO:0030901 9.71 MSX1 SHH
29 positive regulation of BMP signaling pathway GO:0030513 9.71 BMP4 MSX1
30 embryonic forelimb morphogenesis GO:0035115 9.71 MSX1 SHH
31 face morphogenesis GO:0060325 9.71 MSX1 PAX9
32 cell fate commitment GO:0045165 9.71 BMP4 FGF8 SHH
33 endoderm development GO:0007492 9.7 BMP4 PAX9
34 branching involved in blood vessel morphogenesis GO:0001569 9.7 FGF8 SHH
35 pituitary gland development GO:0021983 9.7 BMP4 MSX1
36 branching morphogenesis of an epithelial tube GO:0048754 9.7 BMP4 SHH
37 embryonic digit morphogenesis GO:0042733 9.7 BMP4 MSX1 SHH
38 neuron fate commitment GO:0048663 9.69 BMP4 SHH
39 telencephalon development GO:0021537 9.69 BMP4 FGF8
40 thyroid gland development GO:0030878 9.69 FGF8 SHH
41 odontogenesis of dentin-containing tooth GO:0042475 9.69 BMP4 MSX1 SHH
42 outflow tract septum morphogenesis GO:0003148 9.68 BMP4 FGF8
43 vasculature development GO:0001944 9.68 BMP4 SHH
44 dopaminergic neuron differentiation GO:0071542 9.68 FGF8 SHH
45 anatomical structure formation involved in morphogenesis GO:0048646 9.68 BMP4 SHH
46 renal system development GO:0072001 9.67 BMP4 SHH
47 signal transduction involved in regulation of gene expression GO:0023019 9.67 FGF8 MSX1
48 male genitalia development GO:0030539 9.67 FGF8 SHH
49 embryonic limb morphogenesis GO:0030326 9.67 BMP4 MSX1 SHH
50 embryonic morphogenesis GO:0048598 9.66 BMP4 SHH

Molecular functions related to Tooth Size according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemoattractant activity GO:0042056 8.62 BMP4 FGF8

Sources for Tooth Size

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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