MCID: TXC003
MIFTS: 33

Toxicodendron Dermatitis

Categories: Immune diseases, Skin diseases

Aliases & Classifications for Toxicodendron Dermatitis

MalaCards integrated aliases for Toxicodendron Dermatitis:

Name: Toxicodendron Dermatitis 12 15 17
Dermatitis, Toxicodendron 43 71
Contact Dermatitis Due to Genus Toxicodendron 12
Dermatitis Toxicodendron 54
Rhus Dermatitis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3819
MeSH 43 D011040
SNOMED-CT 67 410049000
UMLS 71 C0032342

Summaries for Toxicodendron Dermatitis

Disease Ontology : 12 An allergic contact dermatitis that has allergic trigger members of the toxicodendron family, including urushiol producing poison ivy, poison oak, and poison sumac, has symptom pruritic erythematous rash with papules, vesicles, and plaques, and has material basis in a type IV hypersensitivity reaction.

MalaCards based summary : Toxicodendron Dermatitis, also known as dermatitis, toxicodendron, is related to dermatitis and irritant dermatitis, and has symptoms including pruritic erythematous rash An important gene associated with Toxicodendron Dermatitis is CXCL8 (C-X-C Motif Chemokine Ligand 8), and among its related pathways/superpathways are Measles and Allograft rejection. Affiliated tissues include skin and t cells, and related phenotypes are cardiovascular system and cellular

Related Diseases for Toxicodendron Dermatitis

Diseases related to Toxicodendron Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 356)
# Related Disease Score Top Affiliating Genes
1 dermatitis 30.7 TNF IL2 CXCL8
2 irritant dermatitis 30.0 TNF CXCL8
3 allergic contact dermatitis 29.2 TNF SELL SELE ICAM1 CXCL8
4 erythema multiforme 29.2 TNF IL2 ICAM1 CXCL8
5 cellulitis 29.2 TNF IL2 CD8A
6 exanthem 29.1 TNF IL2 CXCL8 CD8A
7 contact dermatitis 29.1 TNF SELE IL2 ICAM1 CXCL8
8 proteasome-associated autoinflammatory syndrome 1 28.7 TNF SELL SELE ICAM1 CXCL8
9 herpes simplex virus keratitis 10.4 ICAM1 CXCL8
10 bronchopulmonary dysplasia 10.3 SELL CXCL8
11 myasthenic syndrome, congenital, 1a, slow-channel 10.3 HCCS CXCL8
12 retinal vascular occlusion 10.3 ICAM1 CXCL8
13 diabetic peripheral angiopathy 10.2 SELE ICAM1
14 heterophyiasis 10.2 SELE ICAM1
15 fixed drug eruption 10.2 SELL IL2
16 mooren's ulcer 10.2 SELE ICAM1
17 wells syndrome 10.2 IL2 CXCL8
18 aztreonam allergy 10.2 IL2 HCCS
19 relapsing polychondritis 10.1 IL2 CXCL8
20 b-cell expansion with nfkb and t-cell anergy 10.1 SELL IL2
21 acute hemorrhagic encephalitis 10.1 ICAM1 CD8A
22 neutrophil migration 10.1 ICAM1 CXCL8
23 hydrocele 10.1 SELE ICAM1
24 necrotizing fasciitis 10.1 IL2 CXCL8
25 periapical granuloma 10.1 IL2 CXCL8
26 autoimmune glomerulonephritis 10.1 ICAM1 CD8A
27 chronic active epstein-barr virus infection 10.1 SELE IL2
28 idiopathic anterior uveitis 10.0 TNF CXCL8
29 haemophilus influenzae 10.0 TNF CXCL8
30 mycobacterium abscessus 10.0 TNF CXCL8
31 cardiac rupture 10.0 TNF CXCL8
32 transverse myelitis 10.0 TNF CXCL8
33 aspiration pneumonitis 10.0 TNF CXCL8
34 nickel allergic contact dermatitis 10.0 SELE CD8A
35 pustulosis of palm and sole 10.0 TNF CXCL8
36 mastitis 10.0 SELE ICAM1 CXCL8
37 macular degeneration, age-related, 9 10.0 SELL SELE ICAM1
38 tuberculous meningitis 10.0 TNF CXCL8
39 plummer's disease 10.0 SELL SELE ICAM1
40 progressive myoclonus epilepsy 8 10.0 TNF CXCL8
41 chlamydia pneumonia 10.0 TNF CXCL8
42 peptic esophagitis 10.0 TNF CXCL8
43 polyarteritis nodosa 10.0 SELL SELE ICAM1
44 sapho syndrome 10.0 TNF CXCL8
45 periapical periodontitis 10.0 TNF CXCL8
46 dental pulp disease 10.0 TNF CXCL8
47 leukocyte adhesion deficiency, type i 10.0 SELL SELE ICAM1
48 vaginal discharge 10.0 TNF CXCL8
49 granulocytopenia 10.0 TNF SELL
50 background diabetic retinopathy 10.0 TNF ICAM1

Graphical network of the top 20 diseases related to Toxicodendron Dermatitis:



Diseases related to Toxicodendron Dermatitis

Symptoms & Phenotypes for Toxicodendron Dermatitis

Symptoms:

12
  • pruritic erythematous rash

MGI Mouse Phenotypes related to Toxicodendron Dermatitis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.87 HCCS ICAM1 IL2 LDB3 SELE SELL
2 cellular MP:0005384 9.8 CD8A HCCS ICAM1 IL2 SELE SELL
3 endocrine/exocrine gland MP:0005379 9.63 CD8A ICAM1 IL2 LDB3 SELL TNF
4 mortality/aging MP:0010768 9.56 CD8A HCCS ICAM1 IL2 LDB3 SELE
5 respiratory system MP:0005388 9.02 IL2 LDB3 SELE SELL TNF

Drugs & Therapeutics for Toxicodendron Dermatitis

Search Clinical Trials , NIH Clinical Center for Toxicodendron Dermatitis

Cochrane evidence based reviews: dermatitis, toxicodendron

Genetic Tests for Toxicodendron Dermatitis

Anatomical Context for Toxicodendron Dermatitis

MalaCards organs/tissues related to Toxicodendron Dermatitis:

40
Skin, T Cells

Publications for Toxicodendron Dermatitis

Articles related to Toxicodendron Dermatitis:

(show all 16)
# Title Authors PMID Year
1
Cost and diagnostic characteristics of toxicodendron dermatitis in the USA: a retrospective cross-sectional analysis. 61
32294234 2020
2
Postexposure prevention of Toxicodendron dermatitis by early forceful unidirectional washing with liquid dishwashing soap. 61
29410167 2019
3
Toxicodendron dermatitis in the UK. 61
16863516 2006
4
Toxicodendron dermatitis: poison ivy, oak, and sumac. 61
16805148 2006
5
Treatment of toxicodendron dermatitis (poison ivy and poison oak). 61
11376396 2001
6
Cost-effective post-exposure prevention of poison ivy dermatitis. 61
10940115 2000
7
Rhus (Toxicodendron) dermatitis. 61
10815057 2000
8
Effectiveness of various barrier preparations in preventing and/or ameliorating experimentally produced Toxicodendron dermatitis. 61
1430354 1992
9
Modulation of leucocyte adhesion molecules, a T-cell chemotaxin (IL-8) and a regulatory cytokine (TNF-alpha) in allergic contact dermatitis (rhus dermatitis). 54
1712219 1991
10
Toxicodendron dermatitis. 61
2970948 1988
11
Toxicodendron radicans dermatitis with black lacquer deposit on the skin. 61
6461673 1982
12
Therapeutic use of triamcinolone (kenacort), especially in toxicodendron dermatitis and chronic bronchial asthma. 61
13637696 1959
13
The effect of hydrous zirconium oxide on Rhus toxicodendron dermatitis; further laboratory experience. 61
24543391 1955
14
Zirconium salts in prevention and treatment of rhus toxicodendron dermatitis. 61
14943274 1952
15
Complications of poison ivy (rhus toxicodendron) dermatitis. 61
14911019 1952
16
Prophylaxis of Rhus toxicodendron dermatitis. 61
15408998 1950

Variations for Toxicodendron Dermatitis

Expression for Toxicodendron Dermatitis

Search GEO for disease gene expression data for Toxicodendron Dermatitis.

Pathways for Toxicodendron Dermatitis

Pathways related to Toxicodendron Dermatitis according to GeneCards Suite gene sharing:

(show all 30)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.62 TNF IL2 ICAM1 CXCL8
2
Show member pathways
12.62 TNF IL2 ICAM1 CXCL8 CD8A
3 12.16 TNF IL2 ICAM1
4
Show member pathways
12.15 TNF IL2 CXCL8
5
Show member pathways
12.14 TNF IL2 ICAM1
6 11.92 TNF SELE ICAM1
7 11.9 SELL ICAM1 CD8A
8 11.9 SELL SELE ICAM1 CD8A
9 11.84 TNF IL2 CXCL8
10 11.81 TNF ICAM1 CXCL8
11 11.79 TNF SELE ICAM1
12 11.78 TNF IL2 ICAM1 CXCL8
13 11.75 TNF ICAM1 CXCL8
14 11.73 TNF SELL IL2 CD8A
15 11.69 TNF ICAM1 CXCL8
16 11.62 TNF IL2 CD8A
17 11.62 TNF SELE ICAM1 CXCL8
18
Show member pathways
11.58 TNF IL2 CXCL8
19
Show member pathways
11.47 TNF IL2 CD8A
20 11.47 SELE IL2 ICAM1 CXCL8
21 11.36 TNF ICAM1 CXCL8
22 11.33 TNF SELL IL2 CD8A
23 11.2 TNF SELE ICAM1
24 11.14 IL2 CD8A
25 11.09 TNF IL2
26 11 TNF CXCL8
27 10.96 TNF SELE ICAM1 CXCL8
28 10.9 TNF CXCL8
29
Show member pathways
10.82 TNF SELE IL2 ICAM1 CXCL8
30 10.81 TNF ICAM1

GO Terms for Toxicodendron Dermatitis

Cellular components related to Toxicodendron Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.35 TNF SELL SELE ICAM1 CD8A
2 external side of plasma membrane GO:0009897 8.92 TNF SELL ICAM1 CD8A

Biological processes related to Toxicodendron Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell adhesion GO:0007155 9.73 SELL SELE IL2 ICAM1
2 regulation of immune response GO:0050776 9.65 SELL ICAM1 CD8A
3 immune response GO:0006955 9.62 TNF IL2 CXCL8 CD8A
4 cellular response to lipopolysaccharide GO:0071222 9.58 TNF ICAM1 CXCL8
5 leukocyte cell-cell adhesion GO:0007159 9.46 SELE ICAM1
6 cytokine-mediated signaling pathway GO:0019221 9.46 TNF IL2 ICAM1 CXCL8
7 embryonic digestive tract development GO:0048566 9.37 TNF CXCL8
8 positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996 9.26 TNF ICAM1
9 leukocyte migration GO:0050900 9.26 TNF SELL SELE ICAM1
10 leukocyte tethering or rolling GO:0050901 8.8 TNF SELL SELE

Molecular functions related to Toxicodendron Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.43 TNF IL2 CXCL8
2 carbohydrate binding GO:0030246 9.33 SELL SELE IL2
3 oligosaccharide binding GO:0070492 8.96 SELL SELE
4 glycosphingolipid binding GO:0043208 8.62 SELL IL2

Sources for Toxicodendron Dermatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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