MCID: TXC003
MIFTS: 30

Toxicodendron Dermatitis

Categories: Immune diseases, Skin diseases

Aliases & Classifications for Toxicodendron Dermatitis

MalaCards integrated aliases for Toxicodendron Dermatitis:

Name: Toxicodendron Dermatitis 12 15 17
Dermatitis, Toxicodendron 44 70
Contact Dermatitis Due to Genus Toxicodendron 12
Dermatitis Toxicodendron 54
Rhus Dermatitis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3819
MeSH 44 D011040
SNOMED-CT 67 410049000
UMLS 70 C0032342

Summaries for Toxicodendron Dermatitis

Disease Ontology : 12 An allergic contact dermatitis that has allergic trigger members of the toxicodendron family, including urushiol producing poison ivy, poison oak, and poison sumac, has symptom pruritic erythematous rash with papules, vesicles, and plaques, and has material basis in a type IV hypersensitivity reaction.

MalaCards based summary : Toxicodendron Dermatitis, also known as dermatitis, toxicodendron, is related to irritant dermatitis and cellulitis, and has symptoms including pruritic erythematous rash An important gene associated with Toxicodendron Dermatitis is CXCL8 (C-X-C Motif Chemokine Ligand 8), and among its related pathways/superpathways are Innate Immune System and Toll-like Receptor Signaling Pathway. Affiliated tissues include skin.

Related Diseases for Toxicodendron Dermatitis

Diseases related to Toxicodendron Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 445)
# Related Disease Score Top Affiliating Genes
1 irritant dermatitis 29.9 TNF CXCL8
2 cellulitis 29.6 TNF CD8A
3 dermatitis 29.5 TNF IL2 ICAM1 CXCL8 CD8A
4 erythema multiforme 29.3 TNF IL2 ICAM1 CXCL8
5 allergic contact dermatitis 29.2 TNF SELL SELE ICAM1 CXCL8
6 exanthem 29.2 TNF IL2 CXCL8 CD8A
7 proteasome-associated autoinflammatory syndrome 1 28.9 TNF SELL SELE ICAM1 CXCL8
8 contact dermatitis 28.8 TNF SELL SELE IL2 ICAM1 CXCL8
9 herpes simplex virus keratitis 10.2 ICAM1 CXCL8
10 severe nonproliferative diabetic retinopathy 10.2 ICAM1 CXCL8
11 retinal vascular occlusion 10.2 ICAM1 CXCL8
12 heterophyiasis 10.2 SELE ICAM1
13 bronchopulmonary dysplasia 10.2 SELL CXCL8
14 wells syndrome 10.2 IL2 CXCL8
15 fixed drug eruption 10.1 SELL IL2
16 subacute lymphocytic thyroiditis 10.1 SELL IL2
17 necrotizing fasciitis 10.1 IL2 CXCL8
18 periapical granuloma 10.1 IL2 CXCL8
19 relapsing polychondritis 10.1 IL2 CXCL8
20 mooren's ulcer 10.1 ICAM1 CD8A
21 hydrocele 10.1 SELE ICAM1
22 acute hemorrhagic encephalitis 10.1 ICAM1 CD8A
23 b-cell expansion with nfkb and t-cell anergy 10.1 SELL IL2
24 chronic venous insufficiency 10.1 SELL ICAM1
25 venous insufficiency 10.1 SELL ICAM1
26 chronic active epstein-barr virus infection 10.1 SELE IL2
27 autoimmune glomerulonephritis 10.1 ICAM1 CD8A
28 bullous keratopathy 10.1 SELE CXCL8
29 metal allergy 10.1 IL2 CD8A
30 myelitis 10.0 TNF CXCL8
31 nickel allergic contact dermatitis 10.0 IL2 CD8A
32 idiopathic anterior uveitis 10.0 TNF CXCL8
33 immunodeficiency 41 with lymphoproliferation and autoimmunity 10.0 IL2 CD8A
34 haemophilus influenzae 10.0 TNF CXCL8
35 mycobacterium abscessus 10.0 TNF CXCL8
36 filarial elephantiasis 10.0 IL2 CD8A
37 aspiration pneumonitis 10.0 TNF CXCL8
38 bacterial conjunctivitis 10.0 TNF CXCL8
39 alopecia universalis congenita 10.0 IL2 CD8A
40 cardiac rupture 10.0 TNF CXCL8
41 enterocolitis 10.0 TNF CXCL8
42 anthracosis 10.0 TNF CXCL8
43 progressive myoclonus epilepsy 8 10.0 TNF CXCL8
44 peptic esophagitis 10.0 TNF CXCL8
45 pasteurellosis 10.0 TNF CXCL8
46 pustulosis of palm and sole 10.0 TNF CXCL8
47 tungiasis 10.0 TNF CXCL8
48 tuberculous meningitis 10.0 TNF CXCL8
49 t-cell adult acute lymphocytic leukemia 10.0 IL2 CD8A
50 vaginal discharge 10.0 TNF CXCL8

Graphical network of the top 20 diseases related to Toxicodendron Dermatitis:



Diseases related to Toxicodendron Dermatitis

Symptoms & Phenotypes for Toxicodendron Dermatitis

Symptoms:

12
  • pruritic erythematous rash

Drugs & Therapeutics for Toxicodendron Dermatitis

Search Clinical Trials , NIH Clinical Center for Toxicodendron Dermatitis

Cochrane evidence based reviews: dermatitis, toxicodendron

Genetic Tests for Toxicodendron Dermatitis

Anatomical Context for Toxicodendron Dermatitis

MalaCards organs/tissues related to Toxicodendron Dermatitis:

40
Skin

Publications for Toxicodendron Dermatitis

Articles related to Toxicodendron Dermatitis:

(show all 16)
# Title Authors PMID Year
1
Cost and diagnostic characteristics of toxicodendron dermatitis in the USA: a retrospective cross-sectional analysis. 61
32294234 2020
2
Postexposure prevention of Toxicodendron dermatitis by early forceful unidirectional washing with liquid dishwashing soap. 61
29410167 2019
3
Toxicodendron dermatitis in the UK. 61
16863516 2006
4
Toxicodendron dermatitis: poison ivy, oak, and sumac. 61
16805148 2006
5
Treatment of toxicodendron dermatitis (poison ivy and poison oak). 61
11376396 2001
6
Cost-effective post-exposure prevention of poison ivy dermatitis. 61
10940115 2000
7
Rhus (Toxicodendron) dermatitis. 61
10815057 2000
8
Effectiveness of various barrier preparations in preventing and/or ameliorating experimentally produced Toxicodendron dermatitis. 61
1430354 1992
9
Modulation of leucocyte adhesion molecules, a T-cell chemotaxin (IL-8) and a regulatory cytokine (TNF-alpha) in allergic contact dermatitis (rhus dermatitis). 54
1712219 1991
10
Toxicodendron dermatitis. 61
2970948 1988
11
Toxicodendron radicans dermatitis with black lacquer deposit on the skin. 61
6461673 1982
12
Therapeutic use of triamcinolone (kenacort), especially in toxicodendron dermatitis and chronic bronchial asthma. 61
13637696 1959
13
The effect of hydrous zirconium oxide on Rhus toxicodendron dermatitis; further laboratory experience. 61
24543391 1955
14
Zirconium salts in prevention and treatment of rhus toxicodendron dermatitis. 61
14943274 1952
15
Complications of poison ivy (rhus toxicodendron) dermatitis. 61
14911019 1952
16
Prophylaxis of Rhus toxicodendron dermatitis. 61
15408998 1950

Variations for Toxicodendron Dermatitis

Expression for Toxicodendron Dermatitis

Search GEO for disease gene expression data for Toxicodendron Dermatitis.

Pathways for Toxicodendron Dermatitis

Pathways related to Toxicodendron Dermatitis according to GeneCards Suite gene sharing:

(show all 38)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.75 TNF SELL IL2 ICAM1 CXCL8 CD8A
2
Show member pathways
12.95 TNF SELE IL2 ICAM1 CXCL8
3
Show member pathways
12.62 TNF IL2 ICAM1 CXCL8
4
Show member pathways
12.62 TNF IL2 ICAM1 CXCL8 CD8A
5 12.36 TNF IL2 CD8A
6
Show member pathways
12.31 TNF IL2 ICAM1
7 12.16 TNF IL2 ICAM1
8
Show member pathways
12.15 TNF IL2 CXCL8
9
Show member pathways
12.14 TNF IL2 ICAM1
10 11.93 TNF SELE ICAM1
11 11.93 SELL SELE ICAM1 CD8A
12 11.9 SELL ICAM1 CD8A
13 11.87 TNF IL2 CXCL8 CD8A
14 11.82 TNF ICAM1 CXCL8
15 11.81 TNF SELE ICAM1
16 11.78 TNF IL2 ICAM1 CXCL8
17 11.77 TNF ICAM1 CXCL8
18 11.73 TNF SELL IL2 CD8A
19 11.71 TNF ICAM1 CXCL8
20 11.63 TNF IL2 CD8A
21 11.62 TNF SELE ICAM1 CXCL8
22
Show member pathways
11.59 TNF IL2 CXCL8
23
Show member pathways
11.49 TNF IL2 CD8A
24 11.47 SELE IL2 ICAM1 CXCL8
25 11.38 TNF ICAM1 CXCL8
26 11.33 TNF SELL IL2 CD8A
27 11.32 SELE ICAM1
28 11.31 ICAM1 CXCL8
29 11.25 SELL SELE
30 11.24 TNF SELE ICAM1
31
Show member pathways
11.21 TNF IL2
32 11.14 IL2 CD8A
33 11.11 TNF IL2
34 11.01 TNF CXCL8
35 10.96 TNF SELE ICAM1 CXCL8
36 10.9 TNF CXCL8
37 10.82 TNF ICAM1
38
Show member pathways
10.82 TNF SELE IL2 ICAM1 CXCL8

GO Terms for Toxicodendron Dermatitis

Cellular components related to Toxicodendron Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.55 TNF SELE IL2 ICAM1 CXCL8
2 membrane raft GO:0045121 9.13 TNF SELE ICAM1
3 integral component of plasma membrane GO:0005887 9.02 TNF SELL SELE ICAM1 CD8A

Biological processes related to Toxicodendron Dermatitis according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 cell adhesion GO:0007155 9.73 SELL SELE IL2 ICAM1
2 regulation of immune response GO:0050776 9.63 SELL ICAM1 CD8A
3 cellular response to lipopolysaccharide GO:0071222 9.58 TNF ICAM1 CXCL8
4 immune response GO:0006955 9.56 TNF IL2 CXCL8 CD8A
5 positive regulation of nitric oxide biosynthetic process GO:0045429 9.49 TNF ICAM1
6 leukocyte cell-cell adhesion GO:0007159 9.48 SELE ICAM1
7 cytokine-mediated signaling pathway GO:0019221 9.46 TNF IL2 ICAM1 CXCL8
8 embryonic digestive tract development GO:0048566 9.37 TNF CXCL8
9 positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996 9.32 TNF ICAM1
10 leukocyte migration GO:0050900 9.26 TNF SELL SELE ICAM1
11 leukocyte tethering or rolling GO:0050901 8.8 TNF SELL SELE

Molecular functions related to Toxicodendron Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.43 TNF IL2 CXCL8
2 carbohydrate binding GO:0030246 9.33 SELL SELE IL2
3 oligosaccharide binding GO:0070492 8.96 SELL SELE
4 glycosphingolipid binding GO:0043208 8.62 SELL IL2

Sources for Toxicodendron Dermatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....