MCID: TRC014
MIFTS: 25

Trachea Adenoid Cystic Carcinoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Trachea Adenoid Cystic Carcinoma

MalaCards integrated aliases for Trachea Adenoid Cystic Carcinoma:

Name: Trachea Adenoid Cystic Carcinoma 12 15
Tracheal Adenoid Cystic Carcinoma 12 17
Adenoid Cystic Carcinoma of Trachea 70

Classifications:



External Ids:

Disease Ontology 12 DOID:4875
NCIt 50 C6051
SNOMED-CT 67 254619006
UMLS 70 C0345945

Summaries for Trachea Adenoid Cystic Carcinoma

MalaCards based summary : Trachea Adenoid Cystic Carcinoma, also known as tracheal adenoid cystic carcinoma, is related to adenoid cystic carcinoma and tracheal cancer, and has symptoms including pain An important gene associated with Trachea Adenoid Cystic Carcinoma is ALPI (Alkaline Phosphatase, Intestinal), and among its related pathways/superpathways are PI3K-Akt signaling pathway and C-MYB transcription factor network. Affiliated tissues include trachea and thyroid, and related phenotype is digestive/alimentary.

Related Diseases for Trachea Adenoid Cystic Carcinoma

Diseases related to Trachea Adenoid Cystic Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 53)
# Related Disease Score Top Affiliating Genes
1 adenoid cystic carcinoma 30.3 NFIB MYB KRT5 KIT
2 tracheal cancer 29.7 MYB LPAR3 KRT5 ALPI
3 bronchitis 10.3
4 dysphagia 10.3
5 rare tumor 10.3
6 thyroid tumor 10.3
7 asthma 10.1
8 lung cancer susceptibility 3 10.1
9 chronic asthma 10.1
10 squamous cell carcinoma 10.1
11 tracheal disease 10.1
12 tracheal stenosis 10.1
13 lung squamous cell carcinoma 10.1
14 bronchiectasis 10.1
15 syncope 10.1
16 posttransplant acute limbic encephalitis 10.1
17 virus-associated trichodysplasia spinulosa 10.1
18 thyroid carcinoma 10.1
19 breast secretory carcinoma 9.9 NFIB KRT5
20 cutaneous adenocystic carcinoma 9.9 NFIB KRT5
21 lymphoepithelioma-like thymic carcinoma 9.8 KRT5 KIT
22 ceruminous adenocarcinoma 9.8 KRT5 KIT
23 laryngeal small cell carcinoma 9.8 KRT5 KIT
24 liver fibroma 9.8 KRT5 KIT
25 colon leiomyosarcoma 9.8 KRT5 KIT
26 mucinous stomach adenocarcinoma 9.8 KRT5 KIT
27 breast malignant phyllodes tumor 9.8 KRT5 KIT
28 thymus clear cell carcinoma 9.8 KRT5 KIT
29 liver leiomyosarcoma 9.8 KRT5 KIT
30 lung leiomyosarcoma 9.8 KRT5 KIT
31 esophagus sarcoma 9.8 KRT5 KIT
32 uterus leiomyosarcoma 9.8 KRT5 KIT
33 uterine corpus sarcoma 9.8 KRT5 KIT
34 cribriform carcinoma 9.8 KRT5 KIT
35 heart cancer 9.8 KRT5 KIT
36 bladder sarcoma 9.8 KRT5 KIT
37 dowling-degos disease 1 9.8 KRT5 KIT
38 fibrosarcoma of bone 9.7 MYB KIT
39 mixed cell type cancer 9.7 KRT5 KIT
40 thymus gland disease 9.7 KRT5 KIT
41 thymus cancer 9.7 KRT5 KIT
42 lipomatosis, multiple 9.7 NFIB KIT
43 adenosquamous carcinoma 9.6 KRT5 KIT
44 large cell carcinoma 9.6 KRT5 KIT
45 cervical adenoid cystic carcinoma 9.5 NFIB MYB KIT
46 lung adenoid cystic carcinoma 9.5 NFIB MYB KIT
47 polymorphous low-grade adenocarcinoma 9.5 NFIB MYB KIT
48 synchronous bilateral breast carcinoma 9.5 NFIB KRT5 KIT
49 oropharynx cancer 9.5 NFIB KRT5 KIT
50 salivary gland disease 9.5 NFIB KRT5 KIT

Graphical network of the top 20 diseases related to Trachea Adenoid Cystic Carcinoma:



Diseases related to Trachea Adenoid Cystic Carcinoma

Symptoms & Phenotypes for Trachea Adenoid Cystic Carcinoma

UMLS symptoms related to Trachea Adenoid Cystic Carcinoma:


pain

MGI Mouse Phenotypes related to Trachea Adenoid Cystic Carcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 8.92 ALPI KIT KRT5 NFIB

Drugs & Therapeutics for Trachea Adenoid Cystic Carcinoma

Search Clinical Trials , NIH Clinical Center for Trachea Adenoid Cystic Carcinoma

Genetic Tests for Trachea Adenoid Cystic Carcinoma

Anatomical Context for Trachea Adenoid Cystic Carcinoma

MalaCards organs/tissues related to Trachea Adenoid Cystic Carcinoma:

40
Trachea, Thyroid

Publications for Trachea Adenoid Cystic Carcinoma

Articles related to Trachea Adenoid Cystic Carcinoma:

(show top 50) (show all 55)
# Title Authors PMID Year
1
Endoscopic Resection for Tracheal Adenoid Cystic Carcinoma? Is It Time to Change How We Practice? 61
32710844 2021
2
Clinical features, treatment and outcomes in patients with tracheal adenoid cystic carcinoma: a systematic literature review. 61
33608038 2021
3
A Case of Solid Variant of Adenoid Cystic Carcinoma from Trachea: A Case Report and Review of Literature. 61
33776449 2021
4
Huffing and Puffing: A Rare Case of Tracheal Adenoid Cystic Carcinoma. 61
33415039 2020
5
Metastases from tracheal adenoid cystic carcinoma. 61
33023994 2020
6
[Covered airway stent loaded with (125)I seeds for tracheal adenoid cystic carcinoma: a clinical observation of 8 cases]. 61
32629556 2020
7
Tumor immune microenvironment and mutational analysis of tracheal adenoid cystic carcinoma. 61
32647675 2020
8
Impact of Positive Margins and Radiation After Tracheal Adenoid Cystic Carcinoma Resection on Survival. 61
31589850 2020
9
Multimodal Bronchoscopic Treatment of Unresectable Tracheal Adenoid Cystic Carcinoma. 61
32209920 2020
10
Tracheal Adenoid Cystic Carcinoma Presented with Chronic Asthma Diagnosed by Bronchial Washing Cytology. 61
32015749 2020
11
The incidence of mTOR marker in tracheal adenoid cystic carcinoma by immunohistochemical staining. 61
32869263 2020
12
Syncope due to tracheal adenoid cystic carcinoma. 61
31304017 2019
13
Combined surgery and radiotherapy as curative treatment for tracheal adenoid cystic carcinoma: a case report. 61
30836992 2019
14
Central airway obstruction caused by adenoid cystic carcinoma in pregnancy: a case report and review of the literature. 61
29721318 2018
15
Liver resection for metastases of tracheal adenoid cystic carcinoma: Report of two cases. 61
29778031 2018
16
A 10-year clinical outcome of radiotherapy as an adjuvant or definitive treatment for primary tracheal adenoid cystic carcinoma. 61
29202770 2017
17
Use of Univent tube for intermittent lung isolation during thoracoscopic mediastinal tracheal resection and reconstruction: A case report. 61
29390285 2017
18
Case report of apatinib mesylate treatment in rare advanced tracheal adenoid cystic carcinoma. 61
28892250 2017
19
Percutaneous CT-fluoroscopic-guided radioisotope seed placement for the management of adenoid cystic carcinoma of the trachea. 61
28039009 2017
20
Advanced Tracheal Adenoid Cystic Carcinoma with Thyroid Invasion Mimicking Thyroid Cancer Treated with Definitive Radiation: Case Report and Review of the Literature. 61
28878654 2017
21
Reconstruction of human oncological tracheal defects with xenogenic acellular dermal matrix. 61
27117221 2017
22
Resected Tracheal Adenoid Cystic Carcinoma: Improvements in Outcome at a Single Institution. 61
26431923 2016
23
Video-assisted thoracoscopic surgery tracheal resection and carinal reconstruction for tracheal adenoid cystic carcinoma. 61
26904230 2016
24
Primary tracheal adenoid cystic carcinoma: adjuvant treatment outcome. 61
25412605 2015
25
Laryngeal preservation in managing advanced tracheal adenoid cystic carcinoma. 61
25878915 2015
26
Tracheal adenoid cystic carcinoma mimicking a thyroid tumor: A case report. 61
25120714 2014
27
Tracheal adenoid cystic carcinoma treated by repeated bronchoscopic argon plasma coagulation as a palliative therapy. 61
23575002 2014
28
A case of tracheal adenoid cystic carcinoma in a worker exposed to rubber fumes. 61
24472110 2013
29
[Tracheal adenoid cystic carcinoma treated by complete carinal reconstruction with the help of an ECMO: about a case]. 61
23597633 2013
30
[Tracheal adenoid cystic carcinoma followed by tracheal squamous cell carcinoma: a case report]. 61
23327876 2013
31
Definitive radiotherapy for unresected adenoid cystic carcinoma of the trachea. 61
22553266 2012
32
Prognostic value of pathologic characteristics and resection margins in tracheal adenoid cystic carcinoma. 61
20356756 2010
33
[Tracheal adenoid cystic carcinoma]. 61
21918708 2010
34
Adenoid cystic carcinoma of the trachea metastatic to the nasal cavity: a case report. 61
20013669 2009
35
Primary tracheal adenoid cystic carcinoma with malignant pleural effusion. 61
18310988 2008
36
A long-term survivor after aggressive treatment for tracheal adenoid cystic carcinoma: a case report. 61
17954991 2007
37
[Clinical analysis of 8 cases of tracheal adenoid cystic carcinoma]. 61
21118655 2007
38
Wide sleeve resection of lower trachea through anterior approach with omentopexy. 61
16432124 2006
39
[Tracheal adenoid cystic carcinoma presenting as a thyroid tumor]. 61
17124443 2006
40
Management of difficult airway in intratracheal tumor surgery. 61
15941480 2005
41
Tracheal adenoid cystic carcinoma masquerading asthma: a case report. 61
15494074 2004
42
[Surgery for primary adenoid cystic carcinoma of cervical trachea]. 61
15142459 2004
43
[Surgical treatment of primary tracheal adenoid cystic carcinoma: report of 11 cases]. 61
12921643 2003
44
[A case of tracheal adenoid cystic carcinoma in a young woman]. 61
11732292 2001
45
Primary adenoid cystic carcinoma of the trachea: a case report of a twelve year survivor. 61
7760533 1995
46
Tracheal adenoid cystic carcinoma. 61
1338781 1992
47
[Long-term prognosis of adenoid cystic carcinoma of the trachea]. 61
1661793 1991
48
[Malignant tracheal tumor--differential diagnosis in bronchial asthma]. 61
1665599 1991
49
[A case of primary tracheal adenoid cystic carcinoma performed curative surgical resection]. 61
2165115 1990
50
[Clinical analysis of 11 cases of primary tracheal adenoid cystic carcinoma and review of literature]. 61
2163826 1990

Variations for Trachea Adenoid Cystic Carcinoma

Expression for Trachea Adenoid Cystic Carcinoma

Search GEO for disease gene expression data for Trachea Adenoid Cystic Carcinoma.

Pathways for Trachea Adenoid Cystic Carcinoma

Pathways related to Trachea Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.17 MYB LPAR3 KIT
2 10.85 MYB KIT
3 10.44 NFIB MYB

GO Terms for Trachea Adenoid Cystic Carcinoma

Biological processes related to Trachea Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 activation of MAPK activity GO:0000187 8.96 LPAR3 KIT
2 positive regulation of MAPK cascade GO:0043410 8.62 LPAR3 KIT

Molecular functions related to Trachea Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 8.62 KIT ALPI

Sources for Trachea Adenoid Cystic Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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