MCID: TRC001
MIFTS: 25

Trachea Leiomyoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Trachea Leiomyoma

MalaCards integrated aliases for Trachea Leiomyoma:

Name: Trachea Leiomyoma 12 15
Tracheal Neoplasms 44 73
Leiomyoma of the Trachea 12
Neoplasm of Trachea 12
Tracheal Leiomyoma 73
Tracheal Neoplasm 12
Trachea Neoplasm 12
Tracheal Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:248
MeSH 44 D014134
NCIt 50 C3419 C6049
SNOMED-CT 68 126703006

Summaries for Trachea Leiomyoma

MalaCards based summary : Trachea Leiomyoma, also known as tracheal neoplasms, is related to tracheal cancer and leiomyoma. An important gene associated with Trachea Leiomyoma is NPAT (Nuclear Protein, Coactivator Of Histone Transcription), and among its related pathways/superpathways is Retinoblastoma (RB) in Cancer. The drugs Glucosamine and Antimetabolites have been mentioned in the context of this disorder. Affiliated tissues include trachea.

Related Diseases for Trachea Leiomyoma

Diseases related to Trachea Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 tracheal cancer 11.1
2 leiomyoma 10.1
3 tracheomalacia 10.0 SLC22A4 TEF
4 tracheal stenosis 9.9 SLC22A4 TEF
5 tracheal disease 9.7 SLC22A4 TEF

Graphical network of the top 20 diseases related to Trachea Leiomyoma:



Diseases related to Trachea Leiomyoma

Symptoms & Phenotypes for Trachea Leiomyoma

Drugs & Therapeutics for Trachea Leiomyoma

Drugs for Trachea Leiomyoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 32)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Glucosamine Approved, Investigational, Nutraceutical Phase 1, Phase 2 3416-24-8 439213
2 Antimetabolites Phase 1, Phase 2
3 Anticoagulants Phase 1, Phase 2
4 Fibrinolytic Agents Phase 1, Phase 2
5 Glucuronyl glucosamine glycan sulfate Phase 1, Phase 2
6 Hypoglycemic Agents Phase 1, Phase 2
7 Hypolipidemic Agents Phase 1, Phase 2
8 Lipid Regulating Agents Phase 1, Phase 2
9
Belinostat Approved, Investigational Phase 1 866323-14-0
10
Fluorouracil Approved Phase 1 51-21-8 3385
11 Androgens Phase 1
12 Antimetabolites, Antineoplastic Phase 1
13 Histone Deacetylase Inhibitors Phase 1
14 Immunosuppressive Agents Phase 1
15
Levobupivacaine Approved, Investigational Not Applicable 27262-47-1 92253
16
Atracurium Approved, Experimental, Investigational Not Applicable 64228-79-1 47319
17
Bupivacaine Approved, Investigational Not Applicable 2180-92-9, 38396-39-3 2474
18
Dexmedetomidine Approved, Vet_approved Not Applicable 113775-47-6 68602 5311068
19
Fentanyl Approved, Illicit, Investigational, Vet_approved Not Applicable 437-38-7 3345
20
Propofol Approved, Investigational, Vet_approved Not Applicable 2078-54-8 4943
21 Anesthetics Not Applicable
22 Anesthetics, Local Not Applicable
23 Central Nervous System Depressants Not Applicable
24 Peripheral Nervous System Agents Not Applicable
25 Adrenergic Agents Not Applicable
26 Adrenergic Agonists Not Applicable
27 Adrenergic alpha-2 Receptor Agonists Not Applicable
28 Adrenergic alpha-Agonists Not Applicable
29 Analgesics Not Applicable
30 Analgesics, Non-Narcotic Not Applicable
31 Hypnotics and Sedatives Not Applicable
32 Neurotransmitter Agents Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Airway and/or Pulmonary Vessels Transplantation Recruiting NCT01331863 Phase 1, Phase 2
2 Study of PXD101 Alone and in Combination With 5-Fluorouracil (5-FU) in Patients With Advanced Solid Tumors Completed NCT00413322 Phase 1 belinostat;5-Fluorouracil (5-FU)
3 Local Wound Infiltration for Tracheal Reconstruction Enrolling by invitation NCT02949661 Not Applicable
4 Dexmedetomidine for Bilateral Superficial Cervical Plexus Block for Reconstructive Tracheal Surgery Not yet recruiting NCT03426527 Not Applicable Levobupivacaine;Levobupivacaine-Dexmedetomidine

Search NIH Clinical Center for Trachea Leiomyoma

Cochrane evidence based reviews: tracheal neoplasms

Genetic Tests for Trachea Leiomyoma

Anatomical Context for Trachea Leiomyoma

MalaCards organs/tissues related to Trachea Leiomyoma:

41
Trachea

Publications for Trachea Leiomyoma

Articles related to Trachea Leiomyoma:

# Title Authors Year
1
Primary leiomyoma of the trachea, bronchus, and pulmonary parenchyma--a single-institutional experience. ( 21767960 )
2012
2
Leiomyoma of the trachea. ( 22269742 )
2012
3
Endotracheal surgery for leiomyoma of the trachea. ( 19597402 )
2009

Variations for Trachea Leiomyoma

Expression for Trachea Leiomyoma

Search GEO for disease gene expression data for Trachea Leiomyoma.

Pathways for Trachea Leiomyoma

Pathways related to Trachea Leiomyoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.57 NPAT TOP2A

GO Terms for Trachea Leiomyoma

Cellular components related to Trachea Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ribonucleoprotein complex GO:1990904 8.62 SRA1 TOP2A

Sources for Trachea Leiomyoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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