MCID: TRC017
MIFTS: 15

Trachea Squamous Cell Carcinoma

Categories: Cancer diseases, Respiratory diseases, Skin diseases

Aliases & Classifications for Trachea Squamous Cell Carcinoma

MalaCards integrated aliases for Trachea Squamous Cell Carcinoma:

Name: Trachea Squamous Cell Carcinoma 12 15
Squamous Cell Carcinoma of Trachea 12 73
Tracheal Epidermoid Carcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12003
NCIt 50 C4448
SNOMED-CT 68 254620000
UMLS 73 C0345946

Summaries for Trachea Squamous Cell Carcinoma

MalaCards based summary : Trachea Squamous Cell Carcinoma, also known as squamous cell carcinoma of trachea, is related to squamous cell carcinoma and papillary carcinoma, and has symptoms including coughing, dyspnea and hemoptysis. An important gene associated with Trachea Squamous Cell Carcinoma is SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1). Affiliated tissues include trachea and thyroid.

Related Diseases for Trachea Squamous Cell Carcinoma

Diseases related to Trachea Squamous Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 squamous cell carcinoma 9.9
2 papillary carcinoma 9.9
3 thyroiditis 9.9

Symptoms & Phenotypes for Trachea Squamous Cell Carcinoma

UMLS symptoms related to Trachea Squamous Cell Carcinoma:


coughing, dyspnea, hemoptysis, hoarseness

Drugs & Therapeutics for Trachea Squamous Cell Carcinoma

Search Clinical Trials , NIH Clinical Center for Trachea Squamous Cell Carcinoma

Genetic Tests for Trachea Squamous Cell Carcinoma

Anatomical Context for Trachea Squamous Cell Carcinoma

MalaCards organs/tissues related to Trachea Squamous Cell Carcinoma:

41
Trachea, Thyroid

Publications for Trachea Squamous Cell Carcinoma

Articles related to Trachea Squamous Cell Carcinoma:

# Title Authors Year
1
Primary Squamous Cell Carcinoma of Trachea Arising 4 Years After Radioiodine Treatment of Papillary Carcinoma of Thyroid. ( 26828143 )
2016

Variations for Trachea Squamous Cell Carcinoma

Cosmic variations for Trachea Squamous Cell Carcinoma:

9
(show all 30)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM10659 TP53 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.817C>T p.R273C 17:7673803-7673803 10
2 COSM10758 TP53 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.659A>G p.Y220C 17:7674872-7674872 10
3 COSM6967489 POLE upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.5734G>A p.E1912K 12:132635969-132635969 10
4 COSM6967493 POLD1 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.34G>A p.G12R 19:50398885-50398885 10
5 COSM6967492 PLCG2 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.77C>A p.T26K 16:81786066-81786066 10
6 COSM775 PIK3CA upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.3140A>G p.H1047R 3:179234297-179234297 10
7 COSM254837 NCOR1 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.1446G>C p.K482N 17:16137374-16137374 10
8 COSM6967485 MYCN upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.1184A>T p.N395I 2:15945886-15945886 10
9 COSM6904425 MAP2K1 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.562C>T p.H188Y 15:66444701-66444701 10
10 COSM6967490 IGF1R upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.2737A>T p.N913Y 15:98924639-98924639 10
11 COSM3131842 FAT1 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.2461G>T p.E821* 4:186707367-186707367 10
12 COSM3131843 FAT1 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.2461G>T p.E821* 4:186707367-186707367 10
13 COSM5696573 ERBB4 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.1045G>T p.D349Y 2:211712129-211712129 10
14 COSM19745 CDH1 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.2512A>G p.S838G 16:68833362-68833362 10
15 COSM6962155 ASXL1 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.2068G>C p.D690H 20:32434780-32434780 10
16 COSM3355993 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.659A>G p.Y220C 17:7674872-7674872 10
17 COSM3355991 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.817C>T p.R273C 17:7673803-7673803 10
18 COSM5696574 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.1045G>T p.D349Y 2:211712129-211712129 10
19 COSM99933 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.817C>T p.R273C 17:7673803-7673803 10
20 COSM1645518 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.817C>T p.R273C 17:7673803-7673803 10
21 COSM99720 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.659A>G p.Y220C 17:7674872-7674872 10
22 COSM6967491 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.77C>A p.T26K 16:81786066-81786066 10
23 COSM6962156 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.2053G>C p.D685H 20:32434780-32434780 10
24 COSM6967488 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.5734G>A p.E1912K 12:132635969-132635969 10
25 COSM4908992 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.1446G>C p.K482N 17:16137374-16137374 10
26 COSM6967494 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.34G>A p.G12R 19:50398885-50398885 10
27 COSM6962154 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.1473G>C p.K491N 17:16137374-16137374 10
28 COSM99719 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.380A>G p.Y127C 17:7674872-7674872 10
29 COSM1644277 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.659A>G p.Y220C 17:7674872-7674872 10
30 COSM99718 upper aerodigestive tract,trachea,carcinoma,squamous cell carcinoma c.659A>G p.Y220C 17:7674872-7674872 10

Expression for Trachea Squamous Cell Carcinoma

Search GEO for disease gene expression data for Trachea Squamous Cell Carcinoma.

Pathways for Trachea Squamous Cell Carcinoma

GO Terms for Trachea Squamous Cell Carcinoma

Sources for Trachea Squamous Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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