MCID: TRC016
MIFTS: 20

Tracheal Calcification

Categories: Respiratory diseases

Aliases & Classifications for Tracheal Calcification

MalaCards integrated aliases for Tracheal Calcification:

Name: Tracheal Calcification 12 30 15
Calcification of Trachea 12 74

Classifications:



External Ids:

Disease Ontology 12 DOID:14224
NCIt 51 C35314
SNOMED-CT 69 81089005
UMLS 74 C0264324

Summaries for Tracheal Calcification

MalaCards based summary : Tracheal Calcification, also known as calcification of trachea, is related to hypervitaminosis d and hypophosphatemic rickets, x-linked dominant. An important gene associated with Tracheal Calcification is KL (Klotho), and among its related pathways/superpathways are mTOR signalling and Signaling by FGFR2. Affiliated tissues include trachea.

Related Diseases for Tracheal Calcification

Graphical network of the top 20 diseases related to Tracheal Calcification:



Diseases related to Tracheal Calcification

Symptoms & Phenotypes for Tracheal Calcification

Drugs & Therapeutics for Tracheal Calcification

Search Clinical Trials , NIH Clinical Center for Tracheal Calcification

Genetic Tests for Tracheal Calcification

Genetic tests related to Tracheal Calcification:

# Genetic test Affiliating Genes
1 Tracheal Calcification 30

Anatomical Context for Tracheal Calcification

MalaCards organs/tissues related to Tracheal Calcification:

42
Trachea

Publications for Tracheal Calcification

Articles related to Tracheal Calcification:

# Title Authors Year
1
Tracheal calcification. ( 18663210 )
2008

Variations for Tracheal Calcification

Expression for Tracheal Calcification

Search GEO for disease gene expression data for Tracheal Calcification.

Pathways for Tracheal Calcification

Pathways related to Tracheal Calcification according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.56 FGF23 KL
2
Show member pathways
11.24 FGF23 KL
3 10.65 FGF23 KL

GO Terms for Tracheal Calcification

Cellular components related to Tracheal Calcification according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.13 FGF23 KL NPPB
2 extracellular space GO:0005615 8.8 FGF23 KL NPPB

Biological processes related to Tracheal Calcification according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 MAPK cascade GO:0000165 9.4 FGF23 KL
2 positive regulation of protein kinase B signaling GO:0051897 9.37 FGF23 KL
3 phosphatidylinositol phosphorylation GO:0046854 9.32 FGF23 KL
4 fibroblast growth factor receptor signaling pathway GO:0008543 9.26 FGF23 KL
5 phosphatidylinositol-3-phosphate biosynthetic process GO:0036092 9.16 FGF23 KL
6 regulation of signaling receptor activity GO:0010469 9.13 FGF23 KL NPPB
7 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway GO:0090080 8.62 FGF23 KL

Molecular functions related to Tracheal Calcification according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Ras guanyl-nucleotide exchange factor activity GO:0005088 9.32 FGF23 KL
2 hormone activity GO:0005179 9.26 KL NPPB
3 phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 9.16 FGF23 KL
4 1-phosphatidylinositol-3-kinase activity GO:0016303 8.96 FGF23 KL
5 fibroblast growth factor receptor binding GO:0005104 8.62 FGF23 KL

Sources for Tracheal Calcification

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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