MCID: TRC016
MIFTS: 21

Tracheal Calcification

Categories: Respiratory diseases

Aliases & Classifications for Tracheal Calcification

MalaCards integrated aliases for Tracheal Calcification:

Name: Tracheal Calcification 12 29 15
Calcification of Trachea 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:14224
NCIt 50 C35314
SNOMED-CT 68 81089005
UMLS 73 C0264324

Summaries for Tracheal Calcification

MalaCards based summary : Tracheal Calcification, also known as calcification of trachea, is related to hypervitaminosis d and hypophosphatemic rickets, x-linked dominant. An important gene associated with Tracheal Calcification is KL (Klotho), and among its related pathways/superpathways are Negative regulation of FGFR1 signaling and mTOR signalling. Affiliated tissues include trachea and kidney.

Related Diseases for Tracheal Calcification

Graphical network of the top 20 diseases related to Tracheal Calcification:



Diseases related to Tracheal Calcification

Symptoms & Phenotypes for Tracheal Calcification

Drugs & Therapeutics for Tracheal Calcification

Search Clinical Trials , NIH Clinical Center for Tracheal Calcification

Genetic Tests for Tracheal Calcification

Genetic tests related to Tracheal Calcification:

# Genetic test Affiliating Genes
1 Tracheal Calcification 29

Anatomical Context for Tracheal Calcification

MalaCards organs/tissues related to Tracheal Calcification:

41
Trachea, Kidney

Publications for Tracheal Calcification

Articles related to Tracheal Calcification:

# Title Authors Year
1
Tracheal calcification. ( 18663210 )
2008

Variations for Tracheal Calcification

Expression for Tracheal Calcification

Search GEO for disease gene expression data for Tracheal Calcification.

Pathways for Tracheal Calcification

GO Terms for Tracheal Calcification

Cellular components related to Tracheal Calcification according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.13 FGF23 KL NPPB
2 extracellular space GO:0005615 8.8 FGF23 KL NPPB

Biological processes related to Tracheal Calcification according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 MAPK cascade GO:0000165 9.4 FGF23 KL
2 positive regulation of protein kinase B signaling GO:0051897 9.37 FGF23 KL
3 phosphatidylinositol phosphorylation GO:0046854 9.32 FGF23 KL
4 fibroblast growth factor receptor signaling pathway GO:0008543 9.26 FGF23 KL
5 phosphatidylinositol-3-phosphate biosynthetic process GO:0036092 9.16 FGF23 KL
6 regulation of signaling receptor activity GO:0010469 9.13 FGF23 KL NPPB
7 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway GO:0090080 8.62 FGF23 KL

Molecular functions related to Tracheal Calcification according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Ras guanyl-nucleotide exchange factor activity GO:0005088 9.32 FGF23 KL
2 hormone activity GO:0005179 9.26 KL NPPB
3 phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 9.16 FGF23 KL
4 1-phosphatidylinositol-3-kinase activity GO:0016303 8.96 FGF23 KL
5 fibroblast growth factor receptor binding GO:0005104 8.62 FGF23 KL

Sources for Tracheal Calcification

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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