MCID: TRC025
MIFTS: 31

Tracheal Cancer

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Tracheal Cancer

MalaCards integrated aliases for Tracheal Cancer:

Name: Tracheal Cancer 12 15 37
Malignant Neoplasm of Trachea 71 32
Tracheal Carcinoma 17 71
Pulmonary Sulcus Neoplasm 71
Tracheal Neoplasms 71
Pancoast Syndrome 71
Pancoast Tumor 71

Classifications:



External Ids:

Disease Ontology 12 DOID:11920
ICD9CM 34 162.0
NCIt 49 C9346
SNOMED-CT 67 363432004
ICD10 32 C33
UMLS 71 C0030271 C0040582 C0153489 more

Summaries for Tracheal Cancer

Disease Ontology : 12 A respiratory system cancer that is located in the trachea.

MalaCards based summary : Tracheal Cancer, also known as malignant neoplasm of trachea, is related to trachea carcinoma in situ and adenoid cystic carcinoma. An important gene associated with Tracheal Cancer is ACCS (1-Aminocyclopropane-1-Carboxylate Synthase Homolog (Inactive)). The drugs Vindesine and Cisplatin have been mentioned in the context of this disorder. Affiliated tissues include trachea, lung and bone.

Related Diseases for Tracheal Cancer

Graphical network of the top 20 diseases related to Tracheal Cancer:



Diseases related to Tracheal Cancer

Symptoms & Phenotypes for Tracheal Cancer

Drugs & Therapeutics for Tracheal Cancer

Drugs for Tracheal Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 19)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Vindesine Approved, Investigational Phase 2 59917-39-4, 53643-48-4 40839
2
Cisplatin Approved Phase 2 15663-27-1 2767 441203 84093
3
Docetaxel Approved, Investigational Phase 2 114977-28-5 148124
4
Etoposide Approved Phase 2 33419-42-0 36462
5 Alkylating Agents Phase 2
6 Anti-Bacterial Agents Phase 2
7 Tubulin Modulators Phase 2
8 Mitomycins Phase 2
9 Antibiotics, Antitubercular Phase 2
10 Antimitotic Agents Phase 2
11 Etoposide phosphate Phase 2
12
Fluorouracil Approved Phase 1 51-21-8 3385
13
Parathyroid hormone Approved, Investigational Phase 1 9002-64-6
14
Belinostat Approved, Investigational Phase 1 866323-14-0
15 Immunologic Factors Phase 1
16 Histone Deacetylase Inhibitors Phase 1
17 Androgens Phase 1
18 Immunosuppressive Agents Phase 1
19 Antimetabolites Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Replacement of the Airways and/or the Pulmonary Vessels Using a Cryopreserved Arterial Allograft Unknown status NCT01331863 Phase 1, Phase 2
2 A Phase II Trial of Pre-operative Chemoradiotherapy Followed by Surgical Resection in Pancoast Tumors: Initial Report of Japan Clinical Oncology Group Trial (JCOG 9806) Completed NCT00128037 Phase 2 mitomycin C, vindesine, cisplatin and radiotherapy
3 A Phase II Trial of Induction Chemoradiotherapy With Cisplatin/Etoposide Followed by Surgical Resection, Followed by Docetaxel, for Non-Small Cell Lung Cancer Involving the Superior Sulcus (Pancoast Tumors) Completed NCT00062439 Phase 2 cisplatin;docetaxel;etoposide
4 A Phase I Safety, Pharmacodynamic, Anti-Tumor Activity, and Pharmacokinetic Study of PXD101 Alone and in Combination With 5-Fluorouracil in Patients With Advanced Solid Tumors Completed NCT00413322 Phase 1 belinostat;5-Fluorouracil (5-FU)

Search NIH Clinical Center for Tracheal Cancer

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Tracheal Cancer cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Tracheal Cancer:
InBreath System, a nanofiber scaffold seeded with mononuclear cells for tracheal injuries
Embryonic/Adult Cultured Cells Related to Tracheal Cancer:
Bone marrow-derived mononuclear cells (family)

Genetic Tests for Tracheal Cancer

Anatomical Context for Tracheal Cancer

The Foundational Model of Anatomy Ontology organs/tissues related to Tracheal Cancer:

19
Trachea

MalaCards organs/tissues related to Tracheal Cancer:

40
Trachea, Lung, Bone, Thyroid, Brain

Publications for Tracheal Cancer

Articles related to Tracheal Cancer:

(show top 50) (show all 161)
# Title Authors PMID Year
1
National Utilization of Surgery and Outcomes for Primary Tracheal Cancer in the United States. 61
32335015 2020
2
Cancer incidence and mortality trends in young adults in Metropolitan Lima young adults, 1990-2012. 61
32346391 2020
3
Effects of adjuvant radiation therapy on survival for patients with resected primary tracheal carcinoma: an analysis of the National Cancer Database. 61
30977818 2019
4
Complete Tumor Response of Tracheal Squamous Cell Carcinoma After Treatment With Pembrolizumab. 61
30326234 2019
5
Competing risk analysis of primary tracheal carcinoma based on SEER database. 61
30774433 2019
6
Primary Tracheal Carcinoma. 61
29659419 2018
7
Clinical Characteristics and Prognosis of Primary Tracheal Cancer: A Single Institution Experience. 61
30774830 2018
8
Rare case of radiation-induced primary tracheal carcinoma. 61
29546552 2018
9
Management of Malignant Tracheoesophageal Fistula. 61
30054077 2018
10
Tracheal segmental resection for tracheal cancer: comparison of cervical collar incision with median sternotomy and posterolateral incision. 61
30093998 2018
11
Survival trends in patients with tracheal carcinoma from 1973 to 2011. 61
28927948 2017
12
Successful one-lung ventilation using a bronchial blocker tube for a large tracheal carcinoma resection. 61
28494897 2017
13
Tracheal cancer - treatment results, prognostic factors and incidence of other neoplasms. 61
27904449 2016
14
Marital status is an independent prognostic factor for tracheal cancer patients: an analysis of the SEER database. 61
27780931 2016
15
Dose reconstruction technique using non-rigid registration to evaluate spatial correspondence between high-dose region and late radiation toxicity: a case of tracheobronchial stenosis after external beam radiotherapy combined with endotracheal brachytherapy for tracheal cancer. 61
27257421 2016
16
Diseases Neglected by the Media in Espírito Santo, Brazil in 2011-2012. 61
27115486 2016
17
Resected Tracheal Adenoid Cystic Carcinoma: Improvements in Outcome at a Single Institution. 61
26431923 2016
18
Malignant tracheal tumors: a review of current diagnostic and management strategies. 61
25978628 2015
19
Treatment of tracheal mucoepidermoid carcinoma by argon plasma coagulation during pregnancy. 61
26011218 2015
20
Patient-specific carbon nanocomposite tracheal prosthesis. 61
25633892 2015
21
Sequential stenting for extensive malignant airway stenosis. 61
25273272 2015
22
Intractable obstructive endobronchial granulation caused by surgical materials after sleeve resection for tracheal carcinoma. 61
25468088 2014
23
Pathology of tracheal tumors. 61
24295655 2014
24
Treatment approaches to primary tracheal cancer. 61
24295662 2014
25
Management and prognosis of primary tracheal cancer: a national analysis. 61
23868448 2014
26
Characterization of stem-like cells in mucoepidermoid tracheal paediatric tumor. 61
25229469 2014
27
Diagnosis of laryngotracheal stenosis from routine pulmonary physiology using the expiratory disproportion index. 61
23686716 2013
28
Successful treatment of a tracheal squamous cell carcinoma with a combination of cryoablation and photodynamic therapy. 61
28920198 2013
29
The left thoracotomy approach for excision of distal tracheal carcinoma in the presence of right-sided aorta. 61
23315182 2013
30
Tracheal replacement for primary tracheal cancer. 61
23385784 2013
31
Photodynamic therapy (PDT) may provide effective palliation in the treatment of primary tracheal carcinoma: a small case series. 61
23003123 2012
32
The use of radiation therapy appears to improve outcome in patients with malignant primary tracheal tumors: a SEER-based analysis. 61
22365629 2012
33
Scots Pine (Pinus sylvestris L.) Growth Suppression and Adverse Effects on Human Health Due to Air Pollution in the Upper Silesian Industrial District (USID), Southern Poland. 61
22707804 2012
34
Bioartificial tracheobronchial transplantation. Interview with Paolo Macchiarini. 61
21999257 2011
35
Primary tracheal adenocystic carcinoma and tracheal tumors during pregnancy. 61
22066040 2011
36
Population based cancer registry analysis of primary tracheal carcinoma. 61
20087156 2011
37
Tracheal cancer treated with a short course of external and endoluminal radio-chemotherapy combined with cetuximab - a case report. 61
27853478 2010
38
A primary squamous cell carcinoma of the trachea: case report and review of the literature. 61
21253287 2010
39
Clinical aspects and treatment of primary tracheal malignancies. 61
20569185 2010
40
Bronchoscopic debulking of tracheal carcinoma in 3 cats using a wire snare. 61
20492486 2010
41
[Anesthetic management of laser surgery using PCPS for tracheal tumor]. 61
20560380 2010
42
Indications and results of anterior mediastinal tracheostomy for malignancies. 61
20417783 2010
43
Tracheal cancer: Role of radiation therapy. 61
24376936 2010
44
A simple myocutaneous flap for short-stump mediastinal tracheostomy. 61
19699959 2009
45
[Metastasis to the lateral skull base]. 61
18340421 2009
46
Aortotracheal fistula secondary to bacterial aortitis. 61
19492894 2009
47
Tracheal replacement with cryopreserved, decellularized, or glutaraldehyde-treated aortic allografts. 61
19231406 2009
48
Undertreatment of tracheal carcinoma: multidisciplinary audit of epidemiologic data. 61
19037701 2009
49
Invasion of the recurrent laryngeal nerve by tracheal tumor: an unusual presentation with coincidental huge multinodular goiter. 61
19098590 2008
50
A primary tracheal carcinoid tumor masquerading as chronic obstructive pulmonary disease. 61
18414165 2008

Variations for Tracheal Cancer

Expression for Tracheal Cancer

Search GEO for disease gene expression data for Tracheal Cancer.

Pathways for Tracheal Cancer

GO Terms for Tracheal Cancer

Sources for Tracheal Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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