MCID: TRC025
MIFTS: 31

Tracheal Cancer

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Tracheal Cancer

MalaCards integrated aliases for Tracheal Cancer:

Name: Tracheal Cancer 12 15 37
Malignant Neoplasm of Trachea 71 32
Tracheal Carcinoma 17 71
Pulmonary Sulcus Neoplasm 71
Tracheal Neoplasms 71
Pancoast Syndrome 71
Pancoast Tumor 71

Classifications:



External Ids:

Disease Ontology 12 DOID:11920
ICD9CM 34 162.0
NCIt 49 C9346
ICD10 32 C33
UMLS 71 C0030271 C0040582 C0153489 more

Summaries for Tracheal Cancer

Disease Ontology : 12 A respiratory system cancer that is located in the trachea.

MalaCards based summary : Tracheal Cancer, also known as malignant neoplasm of trachea, is related to trachea carcinoma in situ and adenoid cystic carcinoma. An important gene associated with Tracheal Cancer is ACCS (1-Aminocyclopropane-1-Carboxylate Synthase Homolog (Inactive)). The drugs Cisplatin and Vindesine have been mentioned in the context of this disorder. Affiliated tissues include trachea, lung and bone.

Related Diseases for Tracheal Cancer

Graphical network of the top 20 diseases related to Tracheal Cancer:



Diseases related to Tracheal Cancer

Symptoms & Phenotypes for Tracheal Cancer

Drugs & Therapeutics for Tracheal Cancer

Drugs for Tracheal Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 19)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cisplatin Approved Phase 2 15663-27-1 84093 441203 2767
2
Vindesine Approved, Investigational Phase 2 59917-39-4, 53643-48-4 40839
3
Etoposide Approved Phase 2 33419-42-0 36462
4
Docetaxel Approved, Investigational Phase 2 114977-28-5 148124
5 Alkylating Agents Phase 2
6 Anti-Bacterial Agents Phase 2
7 Antibiotics, Antitubercular Phase 2
8 Mitomycins Phase 2
9 Antimitotic Agents Phase 2
10 Etoposide phosphate Phase 2
11 Topoisomerase Inhibitors Phase 2
12
Fluorouracil Approved Phase 1 51-21-8 3385
13
Belinostat Approved, Investigational Phase 1 866323-14-0
14
Parathyroid hormone Approved, Investigational Phase 1 9002-64-6
15 Immunosuppressive Agents Phase 1
16 Immunologic Factors Phase 1
17 Antimetabolites Phase 1
18 Histone Deacetylase Inhibitors Phase 1
19 Androgens Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Replacement of the Airways and/or the Pulmonary Vessels Using a Cryopreserved Arterial Allograft Unknown status NCT01331863 Phase 1, Phase 2
2 A Phase II Trial of Pre-operative Chemoradiotherapy Followed by Surgical Resection in Pancoast Tumors: Initial Report of Japan Clinical Oncology Group Trial (JCOG 9806) Completed NCT00128037 Phase 2 mitomycin C, vindesine, cisplatin and radiotherapy
3 A Phase II Trial of Induction Chemoradiotherapy With Cisplatin/Etoposide Followed by Surgical Resection, Followed by Docetaxel, for Non-Small Cell Lung Cancer Involving the Superior Sulcus (Pancoast Tumors) Completed NCT00062439 Phase 2 cisplatin;docetaxel;etoposide
4 A Phase I Safety, Pharmacodynamic, Anti-Tumor Activity, and Pharmacokinetic Study of PXD101 Alone and in Combination With 5-Fluorouracil in Patients With Advanced Solid Tumors Completed NCT00413322 Phase 1 belinostat;5-Fluorouracil (5-FU)

Search NIH Clinical Center for Tracheal Cancer

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Tracheal Cancer cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Tracheal Cancer:
InBreath System, a nanofiber scaffold seeded with mononuclear cells for tracheal injuries
Embryonic/Adult Cultured Cells Related to Tracheal Cancer:
Bone marrow-derived mononuclear cells (family)

Genetic Tests for Tracheal Cancer

Anatomical Context for Tracheal Cancer

The Foundational Model of Anatomy Ontology organs/tissues related to Tracheal Cancer:

19
Trachea

MalaCards organs/tissues related to Tracheal Cancer:

40
Trachea, Lung, Bone, Thyroid, Brain

Publications for Tracheal Cancer

Articles related to Tracheal Cancer:

(show top 50) (show all 159)
# Title Authors PMID Year
1
Effects of adjuvant radiation therapy on survival for patients with resected primary tracheal carcinoma: an analysis of the National Cancer Database. 61
30977818 2019
2
Complete Tumor Response of Tracheal Squamous Cell Carcinoma After Treatment With Pembrolizumab. 61
30326234 2019
3
Competing risk analysis of primary tracheal carcinoma based on SEER database. 61
30774433 2019
4
Primary Tracheal Carcinoma. 61
29659419 2018
5
Clinical Characteristics and Prognosis of Primary Tracheal Cancer: A Single Institution Experience. 61
30774830 2018
6
Rare case of radiation-induced primary tracheal carcinoma. 61
29546552 2018
7
Tracheal segmental resection for tracheal cancer: comparison of cervical collar incision with median sternotomy and posterolateral incision. 61
30093998 2018
8
Management of Malignant Tracheoesophageal Fistula. 61
30054077 2018
9
Survival trends in patients with tracheal carcinoma from 1973 to 2011. 61
28927948 2017
10
Successful one-lung ventilation using a bronchial blocker tube for a large tracheal carcinoma resection. 61
28494897 2017
11
Tracheal cancer - treatment results, prognostic factors and incidence of other neoplasms. 61
27904449 2016
12
Marital status is an independent prognostic factor for tracheal cancer patients: an analysis of the SEER database. 61
27780931 2016
13
Diseases Neglected by the Media in Espírito Santo, Brazil in 2011-2012. 61
27115486 2016
14
Dose reconstruction technique using non-rigid registration to evaluate spatial correspondence between high-dose region and late radiation toxicity: a case of tracheobronchial stenosis after external beam radiotherapy combined with endotracheal brachytherapy for tracheal cancer. 61
27257421 2016
15
Resected Tracheal Adenoid Cystic Carcinoma: Improvements in Outcome at a Single Institution. 61
26431923 2016
16
Malignant tracheal tumors: a review of current diagnostic and management strategies. 61
25978628 2015
17
Treatment of tracheal mucoepidermoid carcinoma by argon plasma coagulation during pregnancy. 61
26011218 2015
18
Patient-specific carbon nanocomposite tracheal prosthesis. 61
25633892 2015
19
Sequential stenting for extensive malignant airway stenosis. 61
25273272 2015
20
Intractable obstructive endobronchial granulation caused by surgical materials after sleeve resection for tracheal carcinoma. 61
25468088 2014
21
Pathology of tracheal tumors. 61
24295655 2014
22
Treatment approaches to primary tracheal cancer. 61
24295662 2014
23
Management and prognosis of primary tracheal cancer: a national analysis. 61
23868448 2014
24
Characterization of stem-like cells in mucoepidermoid tracheal paediatric tumor. 61
25229469 2014
25
Diagnosis of laryngotracheal stenosis from routine pulmonary physiology using the expiratory disproportion index. 61
23686716 2013
26
Successful treatment of a tracheal squamous cell carcinoma with a combination of cryoablation and photodynamic therapy. 61
28920198 2013
27
The left thoracotomy approach for excision of distal tracheal carcinoma in the presence of right-sided aorta. 61
23315182 2013
28
Tracheal replacement for primary tracheal cancer. 61
23385784 2013
29
Photodynamic therapy (PDT) may provide effective palliation in the treatment of primary tracheal carcinoma: a small case series. 61
23003123 2012
30
The use of radiation therapy appears to improve outcome in patients with malignant primary tracheal tumors: a SEER-based analysis. 61
22365629 2012
31
Scots Pine (Pinus sylvestris L.) Growth Suppression and Adverse Effects on Human Health Due to Air Pollution in the Upper Silesian Industrial District (USID), Southern Poland. 61
22707804 2012
32
Bioartificial tracheobronchial transplantation. Interview with Paolo Macchiarini. 61
21999257 2011
33
Primary tracheal adenocystic carcinoma and tracheal tumors during pregnancy. 61
22066040 2011
34
Population based cancer registry analysis of primary tracheal carcinoma. 61
20087156 2011
35
Tracheal cancer treated with a short course of external and endoluminal radio-chemotherapy combined with cetuximab - a case report. 61
27853478 2010
36
A primary squamous cell carcinoma of the trachea: case report and review of the literature. 61
21253287 2010
37
Clinical aspects and treatment of primary tracheal malignancies. 61
20569185 2010
38
Bronchoscopic debulking of tracheal carcinoma in 3 cats using a wire snare. 61
20492486 2010
39
[Anesthetic management of laser surgery using PCPS for tracheal tumor]. 61
20560380 2010
40
Indications and results of anterior mediastinal tracheostomy for malignancies. 61
20417783 2010
41
Tracheal cancer: Role of radiation therapy. 61
24376936 2010
42
A simple myocutaneous flap for short-stump mediastinal tracheostomy. 61
19699959 2009
43
[Metastasis to the lateral skull base]. 61
18340421 2009
44
Aortotracheal fistula secondary to bacterial aortitis. 61
19492894 2009
45
Tracheal replacement with cryopreserved, decellularized, or glutaraldehyde-treated aortic allografts. 61
19231406 2009
46
Undertreatment of tracheal carcinoma: multidisciplinary audit of epidemiologic data. 61
19037701 2009
47
Invasion of the recurrent laryngeal nerve by tracheal tumor: an unusual presentation with coincidental huge multinodular goiter. 61
19098590 2008
48
A primary tracheal carcinoid tumor masquerading as chronic obstructive pulmonary disease. 61
18414165 2008
49
A new bronchoscopic treatment of tracheomediastinal fistula using autologous adipose-derived stem cells. 61
18364447 2008
50
Tracheal carcinoma ex pleomorphic adenoma: a rare tumour with potential problems in diagnosis. 61
17916072 2007

Variations for Tracheal Cancer

Expression for Tracheal Cancer

Search GEO for disease gene expression data for Tracheal Cancer.

Pathways for Tracheal Cancer

GO Terms for Tracheal Cancer

Sources for Tracheal Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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