MCID: TRC025
MIFTS: 32

Tracheal Cancer

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Tracheal Cancer

MalaCards integrated aliases for Tracheal Cancer:

Name: Tracheal Cancer 39 12 15
Tracheal Carcinoma 17 74
Malignant Neoplasm of Trachea 74
Pulmonary Sulcus Neoplasm 74
Tracheal Neoplasms 74
Pancoast Syndrome 74
Pancoast Tumor 74

Classifications:



External Ids:

Disease Ontology 12 DOID:11920
ICD9CM 36 162.0
NCIt 51 C9346
ICD10 34 C33

Summaries for Tracheal Cancer

Disease Ontology : 12 A respiratory system cancer that is located in the trachea.

MalaCards based summary : Tracheal Cancer, also known as tracheal carcinoma, is related to trachea carcinoma in situ and trachea carcinoma. An important gene associated with Tracheal Cancer is PGRMC1 (Progesterone Receptor Membrane Component 1). The drugs nivolumab and Ipilimumab have been mentioned in the context of this disorder. Affiliated tissues include trachea, bone and thyroid.

Related Diseases for Tracheal Cancer

Diseases related to Tracheal Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
# Related Disease Score Top Affiliating Genes
1 trachea carcinoma in situ 11.1
2 trachea carcinoma 11.1
3 anus adenocarcinoma 10.1 CEACAM5 SLC5A7
4 bladder calculus 10.0 PGRMC1 SMUG1
5 klatskin's tumor 10.0 PGRMC1 SMUG1
6 liver lymphoma 10.0 CEACAM5 SMUG1
7 gallbladder squamous cell carcinoma 10.0 CEACAM5 SMUG1
8 malignant acrospiroma 10.0 CEACAM5 SMUG1
9 malignant spiradenoma 10.0 CEACAM5 SMUG1
10 tolosa-hunt syndrome 10.0 CEACAM5 SMUG1
11 eccrine adenocarcinoma 10.0 CEACAM5 SMUG1
12 pericardial tuberculosis 10.0 CEACAM5 SMUG1
13 prostate squamous cell carcinoma 10.0 CEACAM5 SMUG1
14 descending colon cancer 9.9 CEACAM5 SMUG1
15 tuberculous peritonitis 9.9 CEACAM5 SMUG1
16 xanthogranulomatous cholecystitis 9.9 CEACAM5 SMUG1
17 pleural disease 9.9 CEACAM5 SMUG1
18 esophageal disease 9.9 CEACAM5 SMUG1
19 intestinal disease 9.9 CEACAM5 SMUG1
20 gastrointestinal system cancer 9.9 CEACAM5 SMUG1
21 endocrine gland cancer 9.9 CEACAM5 SMUG1
22 gastrointestinal system disease 9.8 CEACAM5 SMUG1
23 thyroid cancer, nonmedullary, 2 9.8 CEACAM5 SMUG1
24 trachea adenoid cystic carcinoma 9.8 MYB PGRMC1 SMUG1
25 thyroid carcinoma, familial medullary 9.7 CEACAM5 GRP
26 pneumoconiosis 9.7
27 respiratory failure 9.7
28 pleomorphic adenoma carcinoma 9.7
29 pleomorphic adenoma 9.7
30 adenoma 9.7
31 small cell cancer of the lung 9.6 CEACAM5 GRP
32 pancreas adenocarcinoma 9.6 CEACAM5 SMUG1
33 splenic tuberculosis 9.5 CEACAM5 GRP SMUG1
34 respiratory system cancer 9.5 CEACAM5 GRP SMUG1
35 respiratory system disease 9.5 CEACAM5 GRP SMUG1

Graphical network of the top 20 diseases related to Tracheal Cancer:



Diseases related to Tracheal Cancer

Symptoms & Phenotypes for Tracheal Cancer

Drugs & Therapeutics for Tracheal Cancer

Drugs for Tracheal Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
nivolumab Approved Phase 2 946414-94-4
2
Ipilimumab Approved Phase 2 477202-00-9
3 Immunoglobulins Phase 2
4 Antibodies, Monoclonal Phase 2
5 Antineoplastic Agents, Immunological Phase 2
6 Antibodies Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2

Search NIH Clinical Center for Tracheal Cancer

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Tracheal Cancer cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Tracheal Cancer:
InBreath System, a nanofiber scaffold seeded with mononuclear cells for tracheal injuries
Embryonic/Adult Cultured Cells Related to Tracheal Cancer:
Bone marrow-derived mononuclear cells (family)

Genetic Tests for Tracheal Cancer

Anatomical Context for Tracheal Cancer

MalaCards organs/tissues related to Tracheal Cancer:

42
Trachea, Bone, Thyroid, Brain

The Foundational Model of Anatomy Ontology organs/tissues related to Tracheal Cancer:

20
The Trachea

Publications for Tracheal Cancer

Articles related to Tracheal Cancer:

(show all 45)
# Title Authors Year
1
Competing risk analysis of primary tracheal carcinoma based on SEER database. ( 30774433 )
2019
2
Tracheal segmental resection for tracheal cancer: comparison of cervical collar incision with median sternotomy and posterolateral incision. ( 30093998 )
2018
3
Clinical Characteristics and Prognosis of Primary Tracheal Cancer: A Single Institution Experience. ( 30774830 )
2018
4
Rare case of radiation-induced primary tracheal carcinoma. ( 29546552 )
2018
5
Primary Tracheal Carcinoma. ( 29659419 )
2018
6
Successful one-lung ventilation using a bronchial blocker tube for a large tracheal carcinoma resection. ( 28494897 )
2017
7
Survival trends in patients with tracheal carcinoma from 1973 to 2011. ( 28927948 )
2017
8
Marital status is an independent prognostic factor for tracheal cancer patients: an analysis of the SEER database. ( 27780931 )
2016
9
Dose reconstruction technique using non-rigid registration to evaluate spatial correspondence between high-dose region and late radiation toxicity: a case of tracheobronchial stenosis after external beam radiotherapy combined with endotracheal brachytherapy for tracheal cancer. ( 27257421 )
2016
10
Tracheal cancer - treatment results, prognostic factors and incidence of other neoplasms. ( 27904449 )
2016
11
Management and prognosis of primary tracheal cancer: A national analysis. ( 23868448 )
2014
12
Treatment approaches to primary tracheal cancer. ( 24295662 )
2014
13
Intractable obstructive endobronchial granulation caused by surgical materials after sleeve resection for tracheal carcinoma. ( 25468088 )
2014
14
Tracheal replacement for primary tracheal cancer. ( 23385784 )
2013
15
The left thoracotomy approach for excision of distal tracheal carcinoma in the presence of right-sided aorta. ( 23315182 )
2013
16
Photodynamic therapy (PDT) may provide effective palliation in the treatment of primary tracheal carcinoma: a small case series. ( 23003123 )
2012
17
Population based cancer registry analysis of primary tracheal carcinoma. ( 20087156 )
2011
18
Tracheal cancer: Role of radiation therapy. ( 24376936 )
2010
19
Tracheal cancer treated with a short course of external and endoluminal radio-chemotherapy combined with cetuximab - a case report. ( 27853478 )
2010
20
Bronchoscopic debulking of tracheal carcinoma in 3 cats using a wire snare. ( 20492486 )
2010
21
Undertreatment of tracheal carcinoma: multidisciplinary audit of epidemiologic data. ( 19037701 )
2009
22
Incidence and treatment of tracheal cancer: a nationwide study in the Netherlands. ( 17139460 )
2007
23
Advanced tracheal carcinoma--a therapeutic significance of HDR brachytherapy in palliative treatment. ( 15254664 )
2004
24
Clinicopathological investigation of 20 cases of primary tracheal cancer. ( 12493495 )
2003
25
Therapy of rat tracheal carcinoma IC-12 in SCID mice: vascular targeting with [213Bi]-MAb TES-23. ( 12044516 )
2002
26
Tracheal cancer in Denmark: a nationwide study. ( 11251276 )
2001
27
Treatment of primary tracheal carcinoma. The role of external and endoluminal radiotherapy. ( 10650832 )
2000
28
Role of radiation therapy in the treatment of primary tracheal carcinoma. ( 9607345 )
1998
29
Symptoms and signs and their prognostic value in tracheal carcinoma. ( 8286101 )
1993
30
Treatment of primary tracheal carcinoma in Finland in 1967-1985. ( 8323765 )
1993
31
Diagnosis of tracheal carcinoma at chest radiography. ( 1449878 )
1992
32
Occurrence of tracheal carcinoma in Finland. ( 1763640 )
1991
33
Long-term survival after brain metastases from tracheal carcinoma. ( 2319697 )
1990
34
Primary tracheal carcinoma presenting with acute respiratory failure. ( 3345665 )
1988
35
Tracheal carcinoma in a dog. ( 3443693 )
1987
36
Primary tracheal carcinoma: two case reports. ( 3733412 )
1986
37
Tracheal carcinoma following short term tracheostomy in childhood (a case report). ( 3746119 )
1986
38
Tracheal carcinoma presenting as a thyroid cyst. ( 3885927 )
1985
39
Tracheal carcinoma. ( 4057722 )
1985
40
A case report of primary tracheal cancer from leprosy autopsy series with a review of the literature. ( 6520059 )
1984
41
Tracheal carcinoma presenting as a thyroid tumor. ( 6088894 )
1984
42
Tracheal carcinoma obscured by an endotracheal tube. ( 6420755 )
1983
43
Secondary tracheal carcinoma. ( 7288281 )
1981
44
Tracheal carcinoma after tracheostomy. ( 454293 )
1979
45
Primary tracheal carcinoma. A case report. ( 5854617 )
1965

Variations for Tracheal Cancer

Expression for Tracheal Cancer

Search GEO for disease gene expression data for Tracheal Cancer.

Pathways for Tracheal Cancer

GO Terms for Tracheal Cancer

Sources for Tracheal Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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