MCID: TRC025
MIFTS: 30

Tracheal Cancer

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Tracheal Cancer

MalaCards integrated aliases for Tracheal Cancer:

Name: Tracheal Cancer 39 12 15
Tracheal Carcinoma 17 74
Malignant Neoplasm of Trachea 74
Pulmonary Sulcus Neoplasm 74
Tracheal Neoplasms 74
Pancoast Syndrome 74
Pancoast Tumor 74

Classifications:



External Ids:

Disease Ontology 12 DOID:11920
ICD9CM 36 162.0
NCIt 51 C9346
ICD10 34 C33

Summaries for Tracheal Cancer

Disease Ontology : 12 A respiratory system cancer that is located in the trachea.

MalaCards based summary : Tracheal Cancer, also known as tracheal carcinoma, is related to trachea carcinoma in situ and trachea carcinoma. An important gene associated with Tracheal Cancer is PGRMC1 (Progesterone Receptor Membrane Component 1). The drugs nivolumab and Ipilimumab have been mentioned in the context of this disorder. Affiliated tissues include trachea, thyroid and brain.

Related Diseases for Tracheal Cancer

Diseases related to Tracheal Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)
# Related Disease Score Top Affiliating Genes
1 trachea carcinoma in situ 11.2
2 trachea carcinoma 11.1
3 trachea adenoid cystic carcinoma 9.9 MYB PGRMC1
4 anus adenocarcinoma 9.9 CEACAM5 SLC5A7
5 splenic tuberculosis 9.8 CEACAM5 GRP
6 pneumoconiosis 9.7
7 respiratory failure 9.7
8 pleomorphic adenoma carcinoma 9.7
9 pleomorphic adenoma 9.7
10 adenoma 9.7
11 respiratory system cancer 9.7 CEACAM5 GRP
12 respiratory system disease 9.7 CEACAM5 GRP
13 thyroid carcinoma, familial medullary 9.6 CEACAM5 GRP
14 small cell cancer of the lung 9.5 CEACAM5 GRP

Graphical network of the top 20 diseases related to Tracheal Cancer:



Diseases related to Tracheal Cancer

Symptoms & Phenotypes for Tracheal Cancer

Drugs & Therapeutics for Tracheal Cancer

Drugs for Tracheal Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
nivolumab Approved Phase 2 946414-94-4
2
Ipilimumab Approved Phase 2 477202-00-9
3 Immunoglobulins Phase 2
4 Antibodies, Monoclonal Phase 2
5 Antineoplastic Agents, Immunological Phase 2
6 Antibodies Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2

Search NIH Clinical Center for Tracheal Cancer

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Tracheal Cancer cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Tracheal Cancer:
InBreath System, a nanofiber scaffold seeded with mononuclear cells for tracheal injuries
Embryonic/Adult Cultured Cells Related to Tracheal Cancer:
Bone marrow-derived mononuclear cells (family)

Genetic Tests for Tracheal Cancer

Anatomical Context for Tracheal Cancer

MalaCards organs/tissues related to Tracheal Cancer:

42
Trachea, Thyroid, Brain

The Foundational Model of Anatomy Ontology organs/tissues related to Tracheal Cancer:

20
The Trachea

Publications for Tracheal Cancer

Articles related to Tracheal Cancer:

(show all 48)
# Title Authors Year
1
Competing risk analysis of primary tracheal carcinoma based on SEER database. ( 30774433 )
2019
2
Effects of adjuvant radiation therapy on survival for patients with resected primary tracheal carcinoma: an analysis of the National Cancer Database. ( 30977818 )
2019
3
Tracheal segmental resection for tracheal cancer: comparison of cervical collar incision with median sternotomy and posterolateral incision. ( 30093998 )
2018
4
Clinical Characteristics and Prognosis of Primary Tracheal Cancer: A Single Institution Experience. ( 30774830 )
2018
5
Rare case of radiation-induced primary tracheal carcinoma. ( 29546552 )
2018
6
Primary Tracheal Carcinoma. ( 29659419 )
2018
7
Successful one-lung ventilation using a bronchial blocker tube for a large tracheal carcinoma resection. ( 28494897 )
2017
8
Survival trends in patients with tracheal carcinoma from 1973 to 2011. ( 28927948 )
2017
9
Dose reconstruction technique using non-rigid registration to evaluate spatial correspondence between high-dose region and late radiation toxicity: a case of tracheobronchial stenosis after external beam radiotherapy combined with endotracheal brachytherapy for tracheal cancer. ( 27257421 )
2016
10
Marital status is an independent prognostic factor for tracheal cancer patients: an analysis of the SEER database. ( 27780931 )
2016
11
Tracheal cancer - treatment results, prognostic factors and incidence of other neoplasms. ( 27904449 )
2016
12
Management and prognosis of primary tracheal cancer: a national analysis. ( 23868448 )
2014
13
Treatment approaches to primary tracheal cancer. ( 24295662 )
2014
14
Intractable obstructive endobronchial granulation caused by surgical materials after sleeve resection for tracheal carcinoma. ( 25468088 )
2014
15
Tracheal replacement for primary tracheal cancer. ( 23385784 )
2013
16
The left thoracotomy approach for excision of distal tracheal carcinoma in the presence of right-sided aorta. ( 23315182 )
2013
17
Photodynamic therapy (PDT) may provide effective palliation in the treatment of primary tracheal carcinoma: a small case series. ( 23003123 )
2012
18
Population based cancer registry analysis of primary tracheal carcinoma. ( 20087156 )
2011
19
Tracheal cancer: Role of radiation therapy. ( 24376936 )
2010
20
Tracheal cancer treated with a short course of external and endoluminal radio-chemotherapy combined with cetuximab - a case report. ( 27853478 )
2010
21
Bronchoscopic debulking of tracheal carcinoma in 3 cats using a wire snare. ( 20492486 )
2010
22
Undertreatment of tracheal carcinoma: multidisciplinary audit of epidemiologic data. ( 19037701 )
2009
23
Tracheal carcinoma ex pleomorphic adenoma: a rare tumour with potential problems in diagnosis. ( 17916072 )
2007
24
Incidence and treatment of tracheal cancer: a nationwide study in the Netherlands. ( 17139460 )
2007
25
Advanced tracheal carcinoma--a therapeutic significance of HDR brachytherapy in palliative treatment. ( 15254664 )
2004
26
Clinicopathological investigation of 20 cases of primary tracheal cancer. ( 12493495 )
2003
27
Therapy of rat tracheal carcinoma IC-12 in SCID mice: vascular targeting with [213Bi]-MAb TES-23. ( 12044516 )
2002
28
Tracheal cancer in Denmark: a nationwide study. ( 11251276 )
2001
29
Treatment of primary tracheal carcinoma. The role of external and endoluminal radiotherapy. ( 10650832 )
2000
30
Role of radiation therapy in the treatment of primary tracheal carcinoma. ( 9607345 )
1998
31
Tracheal carcinoma and mixed pneumoconiosis. A causal relationship? ( 7716357 )
1995
32
Symptoms and signs and their prognostic value in tracheal carcinoma. ( 8286101 )
1993
33
Treatment of primary tracheal carcinoma in Finland in 1967-1985. ( 8323765 )
1993
34
Diagnosis of tracheal carcinoma at chest radiography. ( 1449878 )
1992
35
Occurrence of tracheal carcinoma in Finland. ( 1763640 )
1991
36
Long-term survival after brain metastases from tracheal carcinoma. ( 2319697 )
1990
37
Primary tracheal carcinoma presenting with acute respiratory failure. ( 3345665 )
1988
38
Tracheal carcinoma in a dog. ( 3443693 )
1987
39
Primary tracheal carcinoma: two case reports. ( 3733412 )
1986
40
Tracheal carcinoma following short term tracheostomy in childhood (a case report). ( 3746119 )
1986
41
Tracheal carcinoma presenting as a thyroid cyst. ( 3885927 )
1985
42
Tracheal carcinoma. ( 4057722 )
1985
43
A case report of primary tracheal cancer from leprosy autopsy series with a review of the literature. ( 6520059 )
1984
44
Tracheal carcinoma presenting as a thyroid tumor. ( 6088894 )
1984
45
Tracheal carcinoma obscured by an endotracheal tube. ( 6420755 )
1983
46
Secondary tracheal carcinoma. ( 7288281 )
1981
47
Tracheal carcinoma after tracheostomy. ( 454293 )
1979
48
Primary tracheal carcinoma. A case report. ( 5854617 )
1965

Variations for Tracheal Cancer

Expression for Tracheal Cancer

Search GEO for disease gene expression data for Tracheal Cancer.

Pathways for Tracheal Cancer

GO Terms for Tracheal Cancer

Sources for Tracheal Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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