MCID: TRC025
MIFTS: 35

Tracheal Cancer

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Tracheal Cancer

MalaCards integrated aliases for Tracheal Cancer:

Name: Tracheal Cancer 38 12 15
Pancoast Tumor 12 15 73
Malignant Neoplasm of Trachea 12 73
Trachea Carcinoma 12 15
Pancoast Syndrome 44 73
Superior Pulmonary Sulcus Syndrome 12
Malignant Superior Sulcus Tumor 12
Malignant Tumor of Trachea 12
Pulmonary Sulcus Neoplasm 73
Malignant Tracheal Tumor 12
Carcinoma of the Trachea 12
Pulmonary Sulcus Tumor 12
Pancoast's Syndrome 12
Tracheal Neoplasms 73
Tracheal Carcinoma 73
Tracheal Neoplasm 12
Pancoast's Tumour 12
Pancoast's Tumor 12
Ca Trachea 12

Classifications:



Summaries for Tracheal Cancer

Disease Ontology : 12 A respiratory system cancer that is located in the trachea.

MalaCards based summary : Tracheal Cancer, also known as pancoast tumor, is related to trachea carcinoma in situ and trachea leiomyoma. An important gene associated with Tracheal Cancer is NT5C1B (5'-Nucleotidase, Cytosolic IB), and among its related pathways/superpathways are Proteoglycans in cancer and Autophagy - animal. The drugs nivolumab and Antibodies have been mentioned in the context of this disorder. Affiliated tissues include the trachea, trachea and bone.

Related Diseases for Tracheal Cancer

Graphical network of the top 20 diseases related to Tracheal Cancer:



Diseases related to Tracheal Cancer

Symptoms & Phenotypes for Tracheal Cancer

Drugs & Therapeutics for Tracheal Cancer

Drugs for Tracheal Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
nivolumab Approved Phase 2 946414-94-4
2 Antibodies Phase 2
3 Immunoglobulins Phase 2
4 Antibodies, Monoclonal Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2

Search NIH Clinical Center for Tracheal Cancer

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Tracheal Cancer cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Tracheal Cancer:
InBreath System, a nanofiber scaffold seeded with mononuclear cells for tracheal injuries
Embryonic/Adult Cultured Cells Related to Tracheal Cancer:
Bone marrow-derived mononuclear cells (family)

Cochrane evidence based reviews: pancoast syndrome

Genetic Tests for Tracheal Cancer

Anatomical Context for Tracheal Cancer

The Foundational Model of Anatomy Ontology organs/tissues related to Tracheal Cancer:

19
The Trachea

MalaCards organs/tissues related to Tracheal Cancer:

41
Trachea, Bone

Publications for Tracheal Cancer

Articles related to Tracheal Cancer:

(show all 12)
# Title Authors Year
1
Marital status is an independent prognostic factor for tracheal cancer patients: an analysis of the SEER database. ( 27780931 )
2016
2
Dose reconstruction technique using non-rigid registration to evaluate spatial correspondence between high-dose region and late radiation toxicity: a case of tracheobronchial stenosis after external beam radiotherapy combined with endotracheal brachytherapy for tracheal cancer. ( 27257421 )
2016
3
Tracheal cancer - treatment results, prognostic factors and incidence of other neoplasms. ( 27904449 )
2016
4
Management and prognosis of primary tracheal cancer: A national analysis. ( 23868448 )
2014
5
Treatment approaches to primary tracheal cancer. ( 24295662 )
2014
6
Tracheal replacement for primary tracheal cancer. ( 23385784 )
2013
7
Tracheal cancer: Role of radiation therapy. ( 24376936 )
2010
8
Tracheal cancer treated with a short course of external and endoluminal radio-chemotherapy combined with cetuximab - a case report. ( 27853478 )
2010
9
Incidence and treatment of tracheal cancer: a nationwide study in the Netherlands. ( 17139460 )
2007
10
Clinicopathological investigation of 20 cases of primary tracheal cancer. ( 12493495 )
2003
11
Tracheal cancer in Denmark: a nationwide study. ( 11251276 )
2001
12
A case report of primary tracheal cancer from leprosy autopsy series with a review of the literature. ( 6520059 )
1984

Variations for Tracheal Cancer

Expression for Tracheal Cancer

Search GEO for disease gene expression data for Tracheal Cancer.

Pathways for Tracheal Cancer

Pathways related to Tracheal Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.26 CTSL MTOR
2 10.73 CTSL MTOR

GO Terms for Tracheal Cancer

Cellular components related to Tracheal Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endomembrane system GO:0012505 8.96 MTOR PGRMC1
2 organelle membrane GO:0031090 8.62 MTOR PGRMC1

Sources for Tracheal Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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