MCID: TRC020
MIFTS: 33

Tracheitis

Categories: Respiratory diseases

Aliases & Classifications for Tracheitis

MalaCards integrated aliases for Tracheitis:

Name: Tracheitis 12 43 15 17 71
Acute Tracheitis 12 71 32
Chronic Tracheitis 12 71
Bacterial Tracheitis 71

Classifications:



External Ids:

Disease Ontology 12 DOID:9392
ICD9CM 34 464.1
MeSH 43 D014136
NCIt 49 C78643
SNOMED-CT 67 26650005 62994001
ICD10 32 J04.1
UMLS 71 C0040584 C0149513 C0264322 more

Summaries for Tracheitis

Disease Ontology : 12 A tracheal disease which involves bacterial infection of the trachea often caused by Staphylococcus aureus and streptococci that follows a recent viral upper respiratory infection. The symptoms include barking croup cough, loud squeaking noise while breathing, scratchy feeling in the throat, high fever, and production of large amounts of pus-filled secretions.

MalaCards based summary : Tracheitis, also known as acute tracheitis, is related to croup and epiglottitis. An important gene associated with Tracheitis is POLI (DNA Polymerase Iota). The drugs Peppermint and Oregano have been mentioned in the context of this disorder. Affiliated tissues include trachea, lung and testes, and related phenotype is Paclitaxel antagonistic effect.

Wikipedia : 74 Tracheitis is an inflammation of the trachea. Although the trachea is usually considered part of the... more...

Related Diseases for Tracheitis

Diseases related to Tracheitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 82)
# Related Disease Score Top Affiliating Genes
1 croup 30.7 SLC22A4 CRP
2 epiglottitis 30.5 SLC22A4 CRP
3 bronchopneumonia 29.4 POLI CRP
4 laryngotracheitis 10.9
5 acute laryngitis 10.8
6 toxic shock syndrome 10.5
7 bronchitis 10.5
8 haemophilus influenzae 10.5
9 herpes simplex 10.4
10 laryngitis 10.4
11 acanthocephaliasis 10.3 POLI BACE1
12 respiratory failure 10.3
13 tracheal stenosis 10.2
14 pneumonia 10.2
15 acquired immunodeficiency syndrome 10.2
16 swine influenza 10.2 POLI BACE1
17 pharyngitis 10.2
18 influenza 10.2
19 bacterial pneumonia 10.2
20 immune deficiency disease 10.1
21 ocular motor apraxia 10.1
22 pulmonary disease, chronic obstructive 10.1
23 lymphoma 10.1
24 adult respiratory distress syndrome 10.1
25 diphtheria 10.1
26 pneumothorax 10.1
27 newcastle disease 10.1
28 conjunctivitis 10.1
29 lung disease 10.1
30 dysphagia 10.1
31 gastroesophageal reflux 9.9
32 ige responsiveness, atopic 9.9
33 otitis media 9.9
34 down syndrome 9.9
35 asthma 9.9
36 human immunodeficiency virus type 1 9.9
37 esophagitis, eosinophilic, 1 9.9
38 aspergillosis 9.9
39 hydrops, lactic acidosis, and sideroblastic anemia 9.9
40 inflammatory bowel disease 9.9
41 follicular lymphoma 9.9
42 colitis 9.9
43 cardiac arrest 9.9
44 neuroretinitis 9.9
45 bacterial infectious disease 9.9
46 tonsillitis 9.9
47 esophagitis 9.9
48 cryptococcosis 9.9
49 necrotizing sialometaplasia 9.9
50 acute cystitis 9.9

Graphical network of the top 20 diseases related to Tracheitis:



Diseases related to Tracheitis

Symptoms & Phenotypes for Tracheitis

GenomeRNAi Phenotypes related to Tracheitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Paclitaxel antagonistic effect GR00113-A-0 8.62 CAMK2G CAMKK1

Drugs & Therapeutics for Tracheitis

Drugs for Tracheitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Peppermint Approved Phase 1, Phase 2
2 Oregano Approved Phase 1, Phase 2
3
Rosemary Experimental Phase 1, Phase 2
4 Eucalyptus Phase 1, Phase 2
5
Clarithromycin Approved 81103-11-9 84029
6 Cytochrome P-450 CYP3A Inhibitors
7 Anti-Infective Agents
8 Cytochrome P-450 Enzyme Inhibitors
9 Anti-Bacterial Agents
10 Anesthetics
11 Antibiotics, Antitubercular
12 Antitubercular Agents
13 Tin Fluorides

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Treatment of Acute Tracheitis and Laryngitis With Essential Oils of Some Aromatic Medical Plants. Completed NCT00611390 Phase 1, Phase 2
2 Evaluation of Effectiveness of the Treatment After Repeated Administration of Klacid®SR in Patients With Upper Respiratory Infection, Exacerbation of Chronic Bronchitis and Mild Community-acquired Pneumonia in Common Clinical Practice in the Czech Republic Completed NCT01130883
3 Evaluation of the Treatment With Klacid SR in Patients With Acute Tracheitis, Tracheobronchitis and Bronchitis, Acute Exacerbation of Chronic Bronchitis and Mild Community-acquired Pneumonia in Common Clinical Practice in Ukraine Completed NCT01095978 Clarithromycin (Klacid SR)
4 Evaluation of the Treatment With Klacid SR in Patients With Acute Tracheitis, Tracheobronchitis and Bronchitis, Acute Exacerbation of Chronic Bronchitis or Mild Community-acquired Bronchopneumonia in Common Clinical Practice in the Slovak Republic Completed NCT01108185
5 Prospective Ⅱ Study of Stereotactic Body Radiation Therapy for Thymoma and Thymic Carcinoma: Therapeutic Effect and Toxicity Assessment Completed NCT03078699
6 Ventilator Associated Complications in Neonate and Small Infant Undergoing Cardiac Surgery Using Cuffed and Uncuffed Tracheal Tubes. The PICU-BG-TT Study Completed NCT03129893
7 Decreasing Antibiotic Use in Infants With Suspected Ventilator-associated Infection Completed NCT03041207

Search NIH Clinical Center for Tracheitis

Cochrane evidence based reviews: tracheitis

Genetic Tests for Tracheitis

Anatomical Context for Tracheitis

MalaCards organs/tissues related to Tracheitis:

40
Trachea, Lung, Testes, Spleen, Spinal Cord, Kidney, Liver

Publications for Tracheitis

Articles related to Tracheitis:

(show top 50) (show all 623)
# Title Authors PMID Year
1
Acute pediatric tracheitis: Distinguishing the disease by tracheostomy status. 61
31884048 2020
2
Research Note: First evidence of infectious bronchitis virus Middle-East GI-23 lineage (Var2-like) in Germany. 61
32036979 2020
3
High Direct Bilirubin Associated With Levoffoxacin Use in a Neonate. 61
31897078 2020
4
Inhibition of IL-6 expression by lignans and other constituents isolated from Schefflera rubriflora C. J. Tseng & G. Hoo. 61
31707125 2020
5
Factors associated with development of early and late pulmonary hypertension in preterm infants with bronchopulmonary dysplasia. 61
31723236 2020
6
Molecular characterization of variant infectious bronchitis virus in China, 2019: Implications for control programmes. 61
31943814 2020
7
Synthesis and characterization of gold nanoparticles from Marsdenia tenacissima and its anticancer activity of liver cancer HepG2 cells. 61
31328556 2019
8
Validation of an Electronic Surveillance Algorithm to Identify Patients With Post-Operative Surgical Site Infections Using National Surgical Quality Improvement Program Pediatric Data. 61
31886513 2019
9
First Report of Isolation of Gallibacterium anatis from Layer Chickens in Morocco with Decrease in Laying Performance. 61
31865689 2019
10
Clinical impact of an antimicrobial stewardship program on high-risk pediatric patients. 61
31311616 2019
11
The relationship between breastfeeding and reported respiratory and gastrointestinal infection rates in young children. 61
31533753 2019
12
Outbreak of Systemic Avian Pox in Canaries (Serinus canaria domestica) Associated with the B1 Subgroup of Avian Pox Viruses. 61
31967439 2019
13
The devil is in the details-Host disease and co-infections are associated with zoonotic pathogen carriage in Norway rats (Rattus norvegicus). 61
31222965 2019
14
Serological, clinical, and risk factors of the Newcastle disease on broilers flocks in Algeria. 61
31528015 2019
15
Measles Hospitalizations at a United States Children's Hospital 2011-2017. 61
31117114 2019
16
Commercial Vaccines and Vaccination Strategies Against Infectious Laryngotracheitis: What We Have Learned and Knowledge Gaps That Remain. 61
31251534 2019
17
Comparison of the short-term and long-term efficacies of the Mycoplasma gallisepticum vaccines ts-11 and 6/85. 61
30773899 2019
18
Fatal necrotic tracheitis by Aviadenovirus in captive Alagoas curassows (Pauxi mitu) extinct from the wild. 61
30663340 2019
19
Epizootic of multi-centric, squamous cell carcinomas in populations of Indo-Pacific humpbacked dolphins Sousa chinensis in Thai waters. 61
31043577 2019
20
Retrospective analysis of infectious laryngotracheitis in backyard chicken flocks in California, 2007-2017, and determination of strain origin by partial ICP4 sequencing. 61
30973073 2019
21
A case of pseudomembranous tracheitis caused by Mycoplasma pneumoniae in an immunocompetent patient. 61
31205923 2019
22
Ammonia induces Treg/Th1 imbalance with triggered NF-κB pathway leading to chicken respiratory inflammation response. 61
30599354 2019
23
Neonatal bronchoscopy: Role in respiratory disease of the newborn-A 7 year experience. 61
30620142 2019
24
Endotracheal intubation results in acute tracheal damage induced by mtDNA/TLR9/NF-κB activity. 61
30548974 2019
25
Retrospective analysis of colistin-resistant bacteria in a tertiary care centre in India. 61
31249209 2019
26
Pediatric Bacterial Tracheitis-A Variable Entity: Case Series with Literature Review. 61
30348058 2019
27
Pathology of wild Norway rats in Vancouver, Canada. 61
30852980 2019
28
[Analysis of the frequency of allocation of Corynebacteria non-diphtheria from patients with inflammatory diseases of the respiratory tract.] 61
31408596 2019
29
Fatal bronchopneumonia caused by skunk adenovirus 1 in an African pygmy hedgehog. 61
30475680 2019
30
Reasons for Donor Lungs Unsuitability After Radiographic Selection. 61
30777535 2019
31
Effect of experimental Ornithobacterium rhinotracheale infection along with live infectious bronchitis vaccination in broiler chickens. 61
30690611 2019
32
FERLAVIRUS-RELATED DEATHS IN A COLLECTION OF VIPERID SNAKES. 61
30592933 2018
33
Mucosal injury following short-term tracheal intubation: A novel animal model and composite tracheal injury score. 61
30186955 2018
34
Safety and utility of direct laryngoscopy and bronchoscopy in patients hospitalized with croup. 61
30138522 2018
35
Autoimmune Tracheal Cartilage Inflammation Responsive to Anti-TNF-α Therapy. 61
29799374 2018
36
A UPLC-MS/MS method for simultaneous determination of five flavonoids from Stellera chamaejasme L. in rat plasma and its application to a pharmacokinetic study. 61
29328498 2018
37
Croup: Diagnosis and Management. 61
29763253 2018
38
Coarse particles and hospital admissions due to respiratory diseases in children. An ecological time series study. 61
29947697 2018
39
Respiratory disease in ball pythons (Python regius) experimentally infected with ball python nidovirus. 61
29329683 2018
40
Performance of the new clinical case definitions of pertussis in pertussis suspected infection and other diagnoses similar to pertussis. 61
30235311 2018
41
The Antitumor Activities of Marsdenia tenacissima. 61
30406035 2018
42
Potential Anti-inflammatory Sesquiterpene Lactones from Eupatorium lindleyanum. 61
28793356 2018
43
Microbiology of Tracheal Secretions: What to Expect with Children and Adolescents with Tracheostomies. 61
29371898 2018
44
Tracheal Resection in a Secretary Bird ( Sagittarius serpentarius) with Granulomatous, Foreign-body Induced Tracheitis. 61
29327961 2017
45
Experimental co-infection of infectious bronchitis and low pathogenic avian influenza H9N2 viruses in commercial broiler chickens. 61
28692924 2017
46
Update on childhood and adult infectious tracheitis. 61
28757125 2017
47
Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study. 61
28770319 2017
48
Pathology and immunohistochemistry study of Newcastle disease field case in chicken in Indonesia. 61
29062196 2017
49
Pseudomonas aeruginosa and post-tracheotomy bacterial respiratory tract infection readmissions. 61
28440922 2017
50
Use of colistin for the treatment of multi drug resistant isolates in neonates. 61
28839297 2017

Variations for Tracheitis

Expression for Tracheitis

Search GEO for disease gene expression data for Tracheitis.

Pathways for Tracheitis

GO Terms for Tracheitis

Molecular functions related to Tracheitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 calmodulin-dependent protein kinase activity GO:0004683 8.62 CAMKK1 CAMK2G

Sources for Tracheitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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