MCID: TRC008
MIFTS: 52

Trachoma

Categories: Eye diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Trachoma

MalaCards integrated aliases for Trachoma:

Name: Trachoma 12 77 54 56 45 15 74
Trachoma, Initial Stage 74
Trachoma, Active Stage 74
Active Stage Trachoma 12
Trachoma Dubium 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11265
MeSH 45 D014141

Summaries for Trachoma

Disease Ontology : 12 A commensal bacterial infectious disease that results in infection located in eye, has material basis in Chlamydia trachomatis (A, B, Ba and C serovars), which is transmitted by contact with eye discharge from the infected person and transmitted by congenital method. The infection causes eyelid to turn inward which makes eyelashes to scratch the cornea.

MalaCards based summary : Trachoma, also known as trachoma, initial stage, is related to chlamydia and malaria. An important gene associated with Trachoma is KIR2DL3 (Killer Cell Immunoglobulin Like Receptor, Two Ig Domains And Long Cytoplasmic Tail 3), and among its related pathways/superpathways are Human T-cell leukemia virus 1 infection and Allograft rejection. The drugs Azithromycin and Permethrin have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and t cells, and related phenotype is muscle.

Wikipedia : 77 Trachoma is an infectious disease caused by bacterium Chlamydia trachomatis. The infection causes a... more...

Related Diseases for Trachoma

Diseases related to Trachoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 159)
# Related Disease Score Top Affiliating Genes
1 chlamydia 32.1 HSPD1 IDO1 IL10 TNF
2 malaria 29.4 HLA-B IDO1 IL10 TNF
3 entropion 11.5
4 onchocerciasis 11.5
5 conjunctivitis 10.7
6 inclusion conjunctivitis 10.6
7 ornithosis 10.6
8 lymphogranuloma venereum 10.5
9 intraocular pressure quantitative trait locus 10.3
10 listeriosis 10.3 IDO1 TNF
11 yemenite deaf-blind hypopigmentation syndrome 10.3
12 punctate inner choroidopathy 10.3 IL10 TNF
13 sympathetic ophthalmia 10.3 HLA-C TNF
14 tropical endomyocardial fibrosis 10.3 IL10 TNF
15 endomyocardial fibrosis 10.3 IL10 TNF
16 multifocal choroiditis 10.3 IL10 TNF
17 choroiditis 10.3 IL10 TNF
18 tungiasis 10.3 IL10 TNF
19 yaws 10.3
20 transient hypogammaglobulinemia 10.3 IL10 TNF
21 cow milk allergy 10.3 IL10 TNF
22 trichuriasis 10.3 IL10 TNF
23 idiopathic achalasia 10.3 IL10 TNF
24 mucocutaneous leishmaniasis 10.3 IL10 TNF
25 chronic graft versus host disease 10.3 IL10 TNF
26 clonorchiasis 10.3 IL10 TNF
27 autoimmune gastritis 10.3 IL10 TNF
28 autoimmune disease of eyes, ear, nose and throat 10.3 IL10 TNF
29 orofacial granulomatosis 10.3 IL10 TNF
30 transverse myelitis 10.3 IL10 TNF
31 post-transplant lymphoproliferative disease 10.3 IL10 TNF
32 primary systemic mycosis 10.3 IL10 TNF
33 mycoplasma pneumoniae pneumonia 10.2 IL10 TNF
34 chronic active epstein-barr virus infection 10.2 IDO1 IL10
35 multidrug-resistant tuberculosis 10.2 IL10 TNF
36 cataract 10.2
37 poliomyelitis 10.2 IL10 TNF
38 eales disease 10.2 IL10 TNF
39 spotted fever 10.2 IL10 TNF
40 salpingitis 10.2 HSPD1 TNF
41 coccidiosis 10.2 IL10 TNF
42 aseptic meningitis 10.2 IL10 TNF
43 plasmodium vivax malaria 10.2 IL10 TNF
44 bacterial sepsis 10.2 IL10 TNF
45 lacrimal apparatus disease 10.2 IL10 TNF
46 commensal bacterial infectious disease 10.2 IL10 TNF
47 churg-strauss syndrome 10.2 IL10 TNF
48 epstein-barr virus-associated gastric carcinoma 10.2 IL10 TNF
49 q fever 10.2 IL10 TNF
50 viral encephalitis 10.2 IL10 TNF

Graphical network of the top 20 diseases related to Trachoma:



Diseases related to Trachoma

Symptoms & Phenotypes for Trachoma

MGI Mouse Phenotypes related to Trachoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 muscle MP:0005369 9.02 ENG HSPD1 IDO1 IL10 TNF

Drugs & Therapeutics for Trachoma

Drugs for Trachoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 37)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 4,Phase 3,Phase 2,Not Applicable 83905-01-5 447043 55185
2
Permethrin Approved, Investigational Phase 4,Phase 2 52645-53-1 40326
3
Tetracycline Approved, Vet_approved Phase 4 60-54-8 5353990
4
Albendazole Approved, Vet_approved Phase 4,Phase 3,Not Applicable 54965-21-8 2082
5
Ivermectin Approved, Investigational, Vet_approved Phase 4,Phase 3,Not Applicable 70288-86-7 6474909
6
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
7
Sulfamethoxazole Approved Phase 4 723-46-6 5329
8
Trimethoprim Approved, Vet_approved Phase 4 738-70-5 5578
9 Antibiotics, Antitubercular Phase 4,Phase 2,Phase 3
10 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Not Applicable
11 Anti-Infective Agents Phase 4,Phase 3,Not Applicable
12 Anthelmintics Phase 4,Phase 3,Not Applicable
13 Antimitotic Agents Phase 4,Phase 3,Not Applicable
14 Antiparasitic Agents Phase 4,Phase 3,Not Applicable
15 Antiprotozoal Agents Phase 4,Phase 3,Not Applicable
16 Antitubercular Agents Phase 4
17 Antimalarials Phase 4
18 Anti-Infective Agents, Urinary Phase 4
19 Trimethoprim, Sulfamethoxazole Drug Combination Phase 4
20 Renal Agents Phase 4
21 Immunologic Factors Phase 4,Phase 1
22 Vaccines Phase 4,Phase 1
23
Diethylcarbamazine Approved, Investigational, Vet_approved Phase 3 90-89-1 3052
24 Ophthalmic Solutions Phase 3,Not Applicable
25 Pharmaceutical Solutions Phase 3,Not Applicable
26 Lipoxygenase Inhibitors Phase 3
27 Insect Repellents Phase 2
28 Protective Agents Phase 2
29
Fluorometholone Approved, Investigational Not Applicable 426-13-1 9878
30
Formaldehyde Approved, Vet_approved Not Applicable 50-00-0 712
31 Lubricant Eye Drops Not Applicable
32 Hormone Antagonists Not Applicable
33 Anti-Inflammatory Agents Not Applicable
34 Anti-Allergic Agents Not Applicable
35 glucocorticoids Not Applicable
36 Hormones Not Applicable
37 Hormones, Hormone Substitutes, and Hormone Antagonists Not Applicable

Interventional clinical trials:

(show all 40)
# Name Status NCT ID Phase Drugs
1 Partnership for Rapid Elimination of Trachoma Completed NCT00792922 Phase 4 Azithromycin;Azithromycin
2 Effect of Intensive Fly Control on Trachoma and Ocular Chlamydia Infection in Tanzania Completed NCT00347763 Phase 4
3 Study of Three Alternatives for Mass Treatment in Trachoma Villages of Tanzania Completed NCT00347607 Phase 4
4 Impact of Water and Health Education Programs on Trachoma and Ocular C. Trachomatis in Niger Completed NCT00348478 Phase 4
5 Impact of Two Alternative Dosing Strategies for Trachoma Control in Niger Completed NCT00618449 Phase 4 Azithromcyin;Azithromycin
6 Trachoma Elimination Follow-up Completed NCT00221364 Phase 4 Mass treatment with oral azithromycin to an entire village
7 Tripartite International Research for the Elimination of Trachoma Completed NCT01202331 Phase 4 mass treatment with oral azithromycin
8 Trachoma Amelioration in Northern Amhara (TANA) Completed NCT00322972 Phase 4 Mass treatment with oral azithromycin to an entire community
9 A Trial of Non-absorbable Versus Absorbable Sutures for Trichiasis Surgery Completed NCT00522860 Phase 4
10 Study of Azithromycin to Prevent Recurrent Trichiasis Following Surgery in Ethiopia Completed NCT00347776 Phase 4 azithromycin;topical tetracycline
11 Mortality Reduction After Oral Azithromycin: Mortality Study Completed NCT02047981 Phase 4 Azithromycin;Placebo
12 Sanitation, Water, and Instruction in Face-washing for Trachoma Recruiting NCT02754583 Phase 4 Azithromycin;Tetracycline;Albendazole
13 Azithromycin to Prevent Post-discharge Morbidity and Mortality in Kenyan Children Recruiting NCT02414399 Phase 4 Azithromycin;Placebo
14 Antibiotic Resistance and Microbiome in Children Aged 6-59 Months in Nouna, Burkina Faso Active, not recruiting NCT03187834 Phase 4 Azithromycin;Amoxicillin;Cotrimoxazole;Placebo
15 Mortality Reduction After Oral Azithromycin: Morbidity Study Enrolling by invitation NCT02048007 Phase 4 Azithromycin;Placebo
16 Trachoma Elimination Study by Focused Antibiotic (TESFA) Not yet recruiting NCT03523156 Phase 4 Azithromycin mass treatment;Azithromycin targeted treatment
17 Kebele Elimination of Trachoma for Ocular Health Not yet recruiting NCT03335072 Phase 4 Azithromycin
18 Cluster RCT of Co-administration Azithromycin, Albendazole & Ivermectin Not yet recruiting NCT03570814 Phase 4 Administration of Albendazole on Day 1;Administration of Ivermectin on Day 1;Administration of Azithromycin on Day 1;Administration of Azithromycin on Day 15
19 Community Health Azithromycin Trial in Burkina Faso Not yet recruiting NCT03676764 Phase 4 Azithromycin;Placebos
20 Azithromycin in Control of Trachoma II Withdrawn NCT00286026 Phase 4 Azithromycin
21 Safety Study of Combined Azithromycin, Ivermectin and Albendazole for Trachoma and Lymphatic Filariasis Withdrawn NCT01903057 Phase 4 azithromycin;ivermectin;albendazole;placebo
22 Efficacy and Safety of 2 Dosing Regimens of T1225 Eye Drops 1.5% Versus Oral Azithromycin in Treatment of Trachoma Completed NCT00356720 Phase 3 Azithromycin
23 Safety of Co-administration of IDA and Azithromycin for NTDs ( ComboNTDs ) Completed NCT03676140 Phase 3 Albendazole on Day 1;Ivermectin on Day 1;Diethylcarbamazine on day 1;Azithromycin on Day 1;Azithromycin on Day 8
24 Prevention of Bacterial Infections in Newborn Completed NCT01800942 Phase 3 Azithromycin and Placebo
25 Pre-delivery Administration of Azithromycin to Prevent Neonatal Sepsis & Death Recruiting NCT03199547 Phase 3 Azithromycin;Placebo Oral Tablet
26 Nepal Elimination of Trachoma Study Withdrawn NCT02176057 Phase 2, Phase 3 Azithromycin
27 Testing Insect Repellents Against Musca Sorbens, the Vector of Trachoma Suspended NCT03813069 Phase 2
28 Safety and Immunogenicity of a Chlamydia Vaccine CTH522 Not yet recruiting NCT03926728 Phase 1
29 A Surveillance and Azithromycin Treatment for Newcomers and Travelers Evaluation: The ASANTE Trial Completed NCT01767506 Not Applicable
30 The Effect of Oral Azithromycin in the Treatment of Chlamydial Conjunctivitis Completed NCT01178762 Not Applicable Azithromycin
31 Modified Instrumentation for Surgery to Correct Trichiasis Completed NCT00886015 Not Applicable
32 Water Uptake for Health in Amhara Pilot Completed NCT02373657 Not Applicable
33 Safety of the Co-administration of Three Drugs for Trachoma and Lymphatic Filariasis Elimination Completed NCT01586169 Not Applicable triple co administration at once of the combination of Albendazole + ivermectin + azithromycin
34 Identification of TT Cases by Community Treatment Assistants: An Assessment Completed NCT01783743 Not Applicable
35 Fluorometholone as Ancillary Therapy for TT Surgery Completed NCT01949454 Not Applicable Fluorometholone 0.1% ophthalmic solution
36 The Effect of Long-Term HEAD START Training on Surgical Skill Levels Completed NCT03135080 Not Applicable
37 A Trial of Epilation Verses Surgery for Minor Trichiasis Completed NCT00522912 Not Applicable
38 Comparison of Ultrasonic Pachymetry With Orbscan in Corneal Haze Completed NCT00439114
39 Histology Evaluation of Radiofrequency Ablation Not yet recruiting NCT03947723 Not Applicable
40 Performance of a Photoscreener for Vision Screening in a Haitian Pediatric Population Withdrawn NCT02655432

Search NIH Clinical Center for Trachoma

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: trachoma

Genetic Tests for Trachoma

Anatomical Context for Trachoma

MalaCards organs/tissues related to Trachoma:

42
Eye, Testes, T Cells, Skin, Spleen, Lymph Node, Tongue

The Foundational Model of Anatomy Ontology organs/tissues related to Trachoma:

20
Eye

Publications for Trachoma

Articles related to Trachoma:

(show top 50) (show all 1936)
# Title Authors Year
1
Community-level Association between Clinical Trachoma and Ocular Chlamydia Infection after MASS Azithromycin Distribution in a Mesoendemic Region of Niger. ( 30957594 )
2019
2
Comment on: 'Association of Chlamydia trachomatis ompA genovar with trachoma phenotypes'. ( 30390052 )
2019
3
Prevalence of active trachoma and associated risk factors among children of the pastoralist population in Madda Walabu rural district, Southeast Ethiopia: a community-based cross-sectional study. ( 31035947 )
2019
4
Impact of mass drug administration of azithromycin for trachoma elimination on prevalence and azithromycin resistance of genital Mycoplasma genitalium infection. ( 30981999 )
2019
5
Response to Comments on Khokhar et al (J Pak Med Assoc. 2018; 68(9): 1300) Active trachoma among children of District Dera Ghazi Khan, Punjab, Pakistan: A cross sectional study. ( 30890853 )
2019
6
Comments on Khokhar et al (J Pak Med Assoc. 2018; 68(9): 1300) Active trachoma among children of District Dera Ghazi Khan, Punjab, Pakistan: A cross sectional study - L ETTER TO THE EDITOR. ( 30890852 )
2019
7
Various Manifestations Of Trachoma In Internally Displaced Rural Population - A Free Eye Camp Based Survey. ( 30868779 )
2019
8
Factors shaping the implementation of the SAFE strategy for trachoma using the Consolidated Framework for Implementation Research: a systematic review. ( 30773102 )
2019
9
Sensitivity and specificity of computer vision classification of eyelid photographs for programmatic trachoma assessment. ( 30742639 )
2019
10
Community-level chlamydial serology for assessing trachoma elimination in trachoma-endemic Niger. ( 30689671 )
2019
11
Assessment of trachoma in suspected endemic areas within 16 provinces in mainland China. ( 30689647 )
2019
12
Self-Reported Side Effects following Mass Administration of Azithromycin to Eliminate Trachoma in Amhara, Ethiopia: Results from a Region-Wide Population-Based Survey. ( 30675840 )
2019
13
Population coverage and factors associated with participation following a mass drug administration of azithromycin for trachoma elimination in Amhara, Ethiopia. ( 30674087 )
2019
14
Trachoma in 3 Amerindian Communities, Venezuelan Amazon, 2018. ( 30561321 )
2019
15
Antimicrobial resistance following mass azithromycin distribution for trachoma: a systematic review. ( 30292480 )
2019
16
Management of trachoma in the Pacific: have we got it wrong? ( 30066471 )
2019
17
Serological and PCR-based markers of ocular Chlamydia trachomatis transmission in northern Ghana after elimination of trachoma as a public health problem. ( 30550537 )
2018
18
Detection of Chlamydiaceae and Chlamydia-like organisms on the ocular surface of children and adults from a trachoma-endemic region. ( 29743637 )
2018
19
Conjunctival transcriptome profiling of Solomon Islanders with active trachoma in the absence of Chlamydia trachomatis infection. ( 29467021 )
2018
20
Longitudinal change in the serology of antibodies to Chlamydia trachomatis pgp3 in children residing in a trachoma area. ( 29476106 )
2018
21
Population-based analysis of ocular Chlamydia trachomatis in trachoma-endemic West African communities identifies genomic markers of disease severity. ( 29482619 )
2018
22
Evaluation of the reproducibility of a serological test for antibodies to Chlamydia trachomatis pgp3: A potential surveillance tool for trachoma programs. ( 29501689 )
2018
23
Association of Chlamydia trachomatis ompA genovar with trachoma phenotypes. ( 29503448 )
2018
24
Clinical signs of trachoma are prevalent among Solomon Islanders who have no persistent markers of prior infection with Chlamydia trachomatis. ( 29588922 )
2018
25
Diversity of Chlamydia trachomatis in Trachoma-Hyperendemic Communities Treated With Azithromycin. ( 29617922 )
2018
26
Prevalence of Chlamydia trachomatis-Specific Antibodies before and after Mass Drug Administration for Trachoma in Community-Wide Surveys of Four Communities in Nepal. ( 29141720 )
2018
27
Sequelae from Epidemic Viral Conjunctivitis Can Be Associated with Inflammatory Trachoma in Schoolchildren? ( 27628039 )
2018
28
Trachoma in the Democratic Republic of the Congo: Results of 46 Baseline Prevalence Surveys Conducted with the Global Trachoma Mapping Project. ( 28850014 )
2018
29
Effectiveness of expanding annual mass azithromycin distribution treatment coverage for trachoma in Niger: a cluster randomised trial. ( 28893761 )
2018
30
The Epidemiology of Trachoma in Mozambique: Results of 96 Population-Based Prevalence Surveys. ( 28910562 )
2018
31
Interventions to maximize facial cleanliness and achieve environmental improvement for trachoma elimination: A review of the grey literature. ( 29370169 )
2018
32
Prevalence of trachoma in the Kayes region of Mali eight years after stopping mass drug administration. ( 29432434 )
2018
33
Prevalence of trachoma in school children in the Marajó Archipelago, Brazilian Amazon, and the impact of the introduction of educational and preventive measures on the disease over eight years. ( 29447155 )
2018
34
Population-based coverage survey results following the mass drug administration of azithromycin for the treatment of trachoma in Amhara, Ethiopia. ( 29451881 )
2018
35
Meibography of Eyes With Sequelae of Trachoma. ( 29504955 )
2018
36
Correction: Prevalence of Active and Latent Yaws in the Solomon Islands 18 Months after Azithromycin Mass Drug Administration for Trachoma. ( 29513663 )
2018
37
Trachoma in Yunnan province of southwestern China: findings from trachoma rapid assessment. ( 29665861 )
2018
38
Non-Chlamydial Bacterial Infection and Progression of Conjunctival Scarring in Trachoma. ( 29847638 )
2018
39
School-Based versus Community-Based Sampling for Trachoma Surveillance. ( 29848403 )
2018
40
Models of Trachoma Transmission and Their Policy Implications: From Control to Elimination. ( 29860288 )
2018
41
Baseline trachoma prevalence in Guinea: Results of national trachoma mapping in 31 health districts. ( 29889826 )
2018
42
Strengthening the links between mapping, planning and global engagement for disease elimination: lessons learnt from trachoma. ( 29907634 )
2018
43
Making gains sustainable: partnering with WASH to stop the transmission of trachoma. ( 29915467 )
2018
44
Trachoma elimination, approaching 2020. ( 29965850 )
2018
45
Arthur Ferguson MacCallan CBE, MD, FRCS (1872-1955), trachoma pioneer and the ophthalmic campaign in Egypt 1903-1923. ( 27316693 )
2018
46
Prevalence of Trachoma in Four Local Government Areas of Jigawa State, Nigeria. ( 30806552 )
2018
47
Prevalence of Trachoma in Kogi State, Nigeria: Results of four Local Government Area-Level Surveys from the Global Trachoma Mapping Project. ( 30806551 )
2018
48
Prevalence of trachoma in the Afar Region of Ethiopia: results of seven population-based surveys from the Global Trachoma Mapping Project. ( 30806550 )
2018
49
Epidemiology of trachoma and its implications for implementing the "SAFE" strategy in Somali Region, Ethiopia: results of 14 population-based prevalence surveys. ( 30806549 )
2018
50
Prevalence of and risk factors for trachoma in Kwara state, Nigeria: Results of eight population-based surveys from the Global Trachoma Mapping Project. ( 30806548 )
2018

Variations for Trachoma

Expression for Trachoma

Search GEO for disease gene expression data for Trachoma.

Pathways for Trachoma

Pathways related to Trachoma according to GeneCards Suite gene sharing:

(show all 14)
# Super pathways Score Top Affiliating Genes
1 12.04 HLA-B HLA-C TNF
2
Show member pathways
11.91 HLA-B HLA-C HSPD1 IL10 KIR2DL3 KLRC2
3 11.89 HSPD1 IL10 TNF
4
Show member pathways
11.83 HLA-B HLA-C IL10 TNF
5
Show member pathways
11.83 HLA-B HLA-C KIR2DL3 KLRC2 TNF
6 11.82 HSPD1 IL10 TNF
7 11.78 HLA-B HLA-C KIR2DL3
8 11.67 HLA-B HLA-C KIR2DL3
9 11.52 ENG IL10 KLRC2 TNF
10 11.19 HSPD1 IL10
11 11.05 IL10 TNF
12 11 IDO1 IL10 TNF
13 10.96 IL10 TNF
14 10.88 HLA-B HLA-C

GO Terms for Trachoma

Cellular components related to Trachoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of lumenal side of endoplasmic reticulum membrane GO:0071556 9.16 HLA-B HLA-C
2 cell surface GO:0009986 9.02 ENG HLA-B HLA-C HSPD1 TNF
3 MHC class I protein complex GO:0042612 8.96 HLA-B HLA-C

Biological processes related to Trachoma according to GeneCards Suite gene sharing:

(show all 27)
# Name GO ID Score Top Affiliating Genes
1 regulation of immune response GO:0050776 9.77 HLA-B HLA-C KIR2DL3
2 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.63 IL10 TNF
3 positive regulation of interferon-gamma production GO:0032729 9.63 HSPD1 TNF
4 antigen processing and presentation GO:0019882 9.62 HLA-B HLA-C
5 negative regulation of T cell proliferation GO:0042130 9.61 IDO1 IL10
6 negative regulation of mitotic cell cycle GO:0045930 9.61 IL10 TNF
7 B cell proliferation GO:0042100 9.6 HSPD1 IL10
8 antigen processing and presentation of peptide antigen via MHC class I GO:0002474 9.58 HLA-B HLA-C
9 negative regulation of interleukin-6 production GO:0032715 9.58 IL10 TNF
10 positive regulation of cytokine secretion GO:0050715 9.57 IL10 TNF
11 regulation of synapse organization GO:0050807 9.56 IL10 TNF
12 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent GO:0002479 9.55 HLA-B HLA-C
13 positive regulation of interleukin-12 production GO:0032735 9.54 HSPD1 IDO1
14 positive regulation of T cell mediated cytotoxicity GO:0001916 9.52 HLA-B HLA-C
15 response to lipopolysaccharide GO:0032496 9.51 IDO1 IL10
16 positive regulation of macrophage activation GO:0043032 9.49 HSPD1 IL10
17 negative regulation of growth of symbiont in host GO:0044130 9.48 IL10 TNF
18 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.46 IL10 TNF
19 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent GO:0002480 9.43 HLA-B HLA-C
20 response to organic substance GO:0010033 9.4 IL10 TNF
21 endothelial cell apoptotic process GO:0072577 9.37 IL10 TNF
22 response to activity GO:0014823 9.32 IL10
23 antigen processing and presentation of endogenous peptide antigen via MHC class Ib GO:0002476 9.32 HLA-B HLA-C
24 negative regulation of cytokine secretion involved in immune response GO:0002740 9.26 IL10 TNF
25 response to glucocorticoid GO:0051384 9.16 IL10 TNF
26 immune response GO:0006955 9.02 HLA-B HLA-C IL10 KIR2DL3 TNF
27 receptor biosynthetic process GO:0032800 8.96 IL10 TNF

Molecular functions related to Trachoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptide antigen binding GO:0042605 8.62 HLA-B HLA-C

Sources for Trachoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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