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MCID: TRN014
MIFTS: 33

Transient Arthritis

Categories: Bone diseases, Skin diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Transient Arthritis

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MalaCards integrated aliases for Transient Arthritis:

Name: Transient Arthritis 12 15 74

Classifications:

MalaCards categories:
Anatomical: Bone diseases Skin diseases
See all MalaCards categories (disease lists)
ICD10: 34


External Ids:

Disease Ontology 12 DOID:2092
ICD9CM 36 716.4 716.40
NCIt 51 C35761
SNOMED-CT 69 66191007
ICD10 34 M12.8
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Summaries for Transient Arthritis

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MalaCards based summary : Transient Arthritis is related to enthesopathy and tenosynovitis. An important gene associated with Transient Arthritis is MRAP (Melanocortin 2 Receptor Accessory Protein), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Tuberculosis. Affiliated tissues include testes, skin and kidney, and related phenotypes are Reduced mammosphere formation and cellular

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Related Diseases for Transient Arthritis

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Diseases in the Arthritis family:

Transient Arthritis

Diseases related to Transient Arthritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 81)
# Related Disease Score Top Affiliating Genes
1 enthesopathy 29.9 MRAP PHB2
2 tenosynovitis 29.8 COMP MRAP TNFRSF1B
3 arthritis 29.7 ACAN IL1A IL6 TGFB1 TNFRSF1B
4 palindromic rheumatism 29.3 MRAP PRTN3 TNFRSF10A TNFRSF1B
5 rheumatoid arthritis 28.5 COMP IL1A IL6 PRTN3 TGFB1 TNFRSF1B
6 bone chondrosarcoma 10.4 ACAN COMP
7 balanitis 10.4 MRAP PHB2
8 pyuria 10.3 ALB MRAP
9 tendinitis 10.3 COMP MRAP PHB2
10 geniculate herpes zoster 10.3 SERPINA1 TNFRSF10A
11 meningovascular neurosyphilis 10.3 ALB MBP
12 cartilage disease 10.3 ACAN COMP TNFRSF10A
13 scleral disease 10.3 MRAP TNFRSF1B
14 pustulosis of palm and sole 10.3 MRAP TNFRSF1B
15 gastritis, familial giant hypertrophic 10.2 ALB SERPINA1
16 bursitis 10.2 MRAP PHB2
17 urethritis 10.2 MRAP PHB2
18 constrictive pericarditis 10.2 ALB SERPINA1
19 iritis 10.2 MRAP PHB2 TNFRSF1B
20 diabetic foot ulcers 10.2 IL6 TGFB1
21 orbital plasma cell granuloma 10.2 MRAP TNFRSF1B
22 chondromalacia 10.2 COMP TNFRSF10A TNFRSF1B
23 hepatic tuberculosis 10.2 ALB SERPINA1
24 dysentery 10.2 ALB IL1A PHB2
25 chronic graft versus host disease 10.2 ALB IL1A
26 leukoregulin 10.2 IL1A TGFB1
27 posterior scleritis 10.2 MRAP PRTN3 TNFRSF10A
28 keratoconjunctivitis sicca 10.2 ALB IL1A IL6
29 uveal disease 10.2 IL6 MRAP TNFRSF1B
30 proteasome-associated autoinflammatory syndrome 1 10.1 ALB IL1A IL6
31 meningoencephalitis 10.1 ALB IL6 MBP
32 rhinoscleroma 10.1 SERPINA1 TNFRSF1B
33 fournier gangrene 10.1 ALB F3
34 laryngitis 10.1 IL6 TGFB1
35 kidney hypertrophy 10.1 ALB TGFB1
36 peripheral nervous system disease 10.1 ALB IL6 MBP
37 aortic valve disease 1 10.1 ACAN MRAP TGFB1
38 nervous system disease 10.1 ALB IL6 MBP
39 carpal tunnel syndrome 10.1 ACAN IL6 TGFB1
40 primary bacterial infectious disease 10.1 ALB IL6 TNFRSF1B
41 gingival disease 10.1 IL1A IL6 TGFB1
42 idiopathic neutropenia 10.1 IL1A IL6 TGFB1
43 gastrointestinal system disease 10.0 ALB IL6 SERPINA1
44 gingival overgrowth 10.0 IL1A IL6 TGFB1
45 chronic orbital inflammation 10.0 MRAP PRTN3 TNFRSF1B
46 guillain-barre syndrome 10.0 ALB MBP TNFRSF1B
47 granulomatous myositis 10.0 PRTN3 TNFRSF1B
48 anterior scleritis 10.0 MRAP PRTN3 TNFRSF1B
49 iga glomerulonephritis 10.0 ALB IL6 TGFB1
50 end stage renal failure 10.0 ALB IL6 TGFB1

Graphical network of the top 20 diseases related to Transient Arthritis:



Diseases related to Transient Arthritis
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Symptoms & Phenotypes for Transient Arthritis

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GenomeRNAi Phenotypes related to Transient Arthritis according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.1 ALB CLEC7A PHB2 PRTN3 TGFB1 TNFRSF1B

MGI Mouse Phenotypes related to Transient Arthritis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.96 ALB COMP F3 IL6 MBP PHB2
2 hematopoietic system MP:0005397 9.81 CLEC7A F3 IL1A IL6 MBP PRTN3
3 immune system MP:0005387 9.65 CLEC7A COMP F3 IL1A IL6 MBP
4 neoplasm MP:0002006 9.17 ALB F3 IL1A IL6 TGFB1 TNFRSF10A
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Drugs & Therapeutics for Transient Arthritis

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Search Clinical Trials , NIH Clinical Center for Transient Arthritis

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Genetic Tests for Transient Arthritis

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Anatomical Context for Transient Arthritis

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MalaCards organs/tissues related to Transient Arthritis:

42
Testes, Skin, Kidney, Spinal Cord
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Publications for Transient Arthritis

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Articles related to Transient Arthritis:

# Title Authors Year
1
Activated partial thromboplastin time sensitivity to lupus anticoagulant in a patient with transient arthritis and lupus anticoagulant-hypoprothrombinemia syndrome. ( 25380995 )
2015
2
Rapid release of high mobility group box protein-1 (HMGB-1) in transient arthritis. ( 20483058 )
2010
3
Induction of transient arthritis by the adoptive transfer of a collagen II specific Th1 clone to HLA-DR4 (B1*0401) transgenic mice. ( 12367557 )
2002
4
Transient arthritis with positive tests for rheumatoid factor as presenting sign of shunt nephritis. ( 2015013 )
1991
5
Tenosynovitis and transient arthritis associated with Haemophilus influenzae type b bacteremia. ( 3261417 )
1988
6
Demonstration and characterization of a transient arthritis in rats following sensitization of synovial mast cells with antigen-specific IgE and parenteral challenge with specific antigen. ( 2457375 )
1988
7
Transient arthritis of the hip in children (a study of 74 cases). ( 6469611 )
1984
8
Transient arthritis after rubella vaccination. ( 5794817 )
1969
9
Acute transient arthritis of the adult hip. Its relation to rheumatoid arthritis and to "palindromic rheumatism". ( 14462616 )
1962
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Variations for Transient Arthritis

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Expression for Transient Arthritis

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Search GEO for disease gene expression data for Transient Arthritis.
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Pathways for Transient Arthritis

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Pathways related to Transient Arthritis according to GeneCards Suite gene sharing:

(show all 14)
# Super pathways Score Top Affiliating Genes
1
Response to elevated platelet cytosolic Ca2+ 67
Show member pathways
 13.09 ALB F3 PRTN3 SERPINA1 TGFB1 TNFRSF10A
2
Tuberculosis 38
12.01 CLEC7A IL1A IL6 TGFB1
3
Immune response IFN gamma signaling pathway 23
Show member pathways
 11.78 IL1A IL6 TGFB1 TNFRSF10A TNFRSF1B
4
Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers 66
11.75 ALB IL6 SERPINA1 TGFB1
5
Senescence and Autophagy in Cancer 1
11.73 IL1A IL6 TGFB1
6
Rheumatoid arthritis 38
11.65 IL1A IL6 TGFB1
7
Interleukin-4 and 13 signaling 67
11.51 IL1A IL6 TGFB1 TNFRSF1B
8
Lung fibrosis 1
11.47 IL6 SERPINA1 TGFB1
9
ECM proteoglycans 67
11.41 ACAN COMP TGFB1
10
Interleukin-10 signaling 67
11.3 IL1A IL6 TNFRSF1B
11
Malaria 38
11.27 COMP IL6 TGFB1
12
AGE-RAGE signaling pathway in diabetic complications 38
11.26 F3 IL1A IL6 TGFB1
13
Spinal Cord Injury 1
11.1 ACAN IL1A IL6 MBP TGFB1
14
Cytokines and Inflammatory Response 1
10.9 IL1A IL6 TGFB1
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GO Terms for Transient Arthritis

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Cellular components related to Transient Arthritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.76 ALB COMP F3 IL1A IL6 PRTN3
2 cell surface GO:0009986 9.72 F3 MBP PHB2 TGFB1 TNFRSF10A
3 extracellular region GO:0005576 9.65 ACAN ALB COMP F3 IL1A IL6
4 platelet alpha granule lumen GO:0031093 9.43 ALB SERPINA1 TGFB1
5 collagen-containing extracellular matrix GO:0062023 9.1 ACAN COMP F3 PRTN3 SERPINA1 TGFB1

Biological processes related to Transient Arthritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet degranulation GO:0002576 9.65 ALB SERPINA1 TGFB1
2 negative regulation of protein localization to plasma membrane GO:1903077 9.46 MRAP TGFB1
3 negative regulation of phagocytosis GO:0050765 9.43 PRTN3 TGFB1
4 connective tissue replacement involved in inflammatory response wound healing GO:0002248 9.4 IL1A TGFB1
5 mammary gland branching involved in thelarche GO:0060744 9.37 PHB2 TGFB1
6 inflammatory response GO:0006954 9.35 CLEC7A IL1A IL6 TGFB1 TNFRSF1B
7 extrinsic apoptotic signaling pathway GO:0097191 9.33 TGFB1 TNFRSF10A TNFRSF1B
8 positive regulation of exit from mitosis GO:0031536 9.32 PHB2 TGFB1
9 regulation of branching involved in mammary gland duct morphogenesis GO:0060762 9.26 PHB2 TGFB1
10 cytokine-mediated signaling pathway GO:0019221 9.1 F3 IL1A IL6 PRTN3 TGFB1 TNFRSF1B

Molecular functions related to Transient Arthritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.83 ACAN ALB CLEC7A COMP F3 IL1A
2 protease binding GO:0002020 9.02 COMP F3 MBP SERPINA1 TNFRSF10A
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Sources for Transient Arthritis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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