MCID: TRN014
MIFTS: 34

Transient Arthritis

Categories: Bone diseases, Skin diseases

Aliases & Classifications for Transient Arthritis

MalaCards integrated aliases for Transient Arthritis:

Name: Transient Arthritis 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:2092
ICD10 33 M12.8
ICD9CM 35 716.4 716.40
NCIt 50 C35761
SNOMED-CT 68 66191007

Summaries for Transient Arthritis

MalaCards based summary : Transient Arthritis is related to arthritis and tenosynovitis. An important gene associated with Transient Arthritis is MRAP (Melanocortin 2 Receptor Accessory Protein), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Tuberculosis. Affiliated tissues include skin, bone and lung, and related phenotypes are Reduced mammosphere formation and cellular

Related Diseases for Transient Arthritis

Diseases in the Arthritis family:

Transient Arthritis

Diseases related to Transient Arthritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 86)
# Related Disease Score Top Affiliating Genes
1 arthritis 29.8 ACAN IL1A IL6 TGFB1 TNFRSF1B
2 tenosynovitis 29.6 COMP MRAP TNFRSF1B
3 palindromic rheumatism 29.3 MRAP PRTN3 TNFRSF10A TNFRSF1B
4 rheumatoid arthritis 28.8 COMP IL1A IL6 PRTN3 TGFB1 TNFRSF1B
5 balanitis 10.2 MRAP PHB2
6 bone chondrosarcoma 10.2 ACAN COMP
7 geniculate herpes zoster 10.2 SERPINA1 TNFRSF10A
8 pyuria 10.2 ALB MRAP
9 enthesopathy 10.2 MRAP PHB2
10 tendinitis 10.2 COMP MRAP PHB2
11 cartilage disease 10.2 ACAN COMP TNFRSF10A
12 meningovascular neurosyphilis 10.2 ALB MBP
13 gastritis, familial giant hypertrophic 10.2 ALB SERPINA1
14 scleral disease 10.2 MRAP TNFRSF1B
15 pustulosis of palm and sole 10.2 MRAP TNFRSF1B
16 bursitis 10.2 MRAP PHB2
17 constrictive pericarditis 10.1 ALB SERPINA1
18 urethritis 10.1 MRAP PHB2
19 hepatic tuberculosis 10.1 ALB SERPINA1
20 diabetic foot ulcers 10.1 IL6 TGFB1
21 iritis 10.1 MRAP PHB2 TNFRSF1B
22 orbital plasma cell granuloma 10.1 MRAP TNFRSF1B
23 chondromalacia 10.1 COMP TNFRSF10A TNFRSF1B
24 dysentery 10.1 ALB IL1A PHB2
25 chronic graft versus host disease 10.1 ALB IL1A
26 leukoregulin 10.1 IL1A TGFB1
27 posterior scleritis 10.1 MRAP PRTN3 TNFRSF10A
28 keratoconjunctivitis sicca 10.1 ALB IL1A IL6
29 uveal disease 10.1 IL6 MRAP TNFRSF1B
30 rhinoscleroma 10.1 SERPINA1 TNFRSF1B
31 proteasome-associated autoinflammatory syndrome 1 10.1 ALB IL1A IL6
32 fournier gangrene 10.1 ALB F3
33 laryngitis 10.1 IL6 TGFB1
34 kidney hypertrophy 10.1 ALB TGFB1
35 meningoencephalitis 10.1 ALB IL6 MBP
36 aortic valve disease 1 10.1 ACAN MRAP TGFB1
37 carpal tunnel syndrome 10.0 ACAN IL6 TGFB1
38 primary bacterial infectious disease 10.0 ALB IL6 TNFRSF1B
39 gastrointestinal system disease 10.0 ALB IL6 SERPINA1
40 peripheral nervous system disease 10.0 ALB IL6 MBP
41 nervous system disease 10.0 ALB IL6 MBP
42 gingival disease 10.0 IL1A IL6 TGFB1
43 idiopathic neutropenia 10.0 IL1A IL6 TGFB1
44 anca-associated vasculitis 10.0 IL6 PRTN3 SERPINA1
45 gingival overgrowth 10.0 IL1A IL6 TGFB1
46 chronic orbital inflammation 10.0 MRAP PRTN3 TNFRSF1B
47 anterior scleritis 10.0 MRAP PRTN3 TNFRSF1B
48 granulomatous myositis 10.0 PRTN3 TNFRSF1B
49 iga glomerulonephritis 10.0 ALB IL6 TGFB1
50 end stage renal failure 10.0 ALB IL6 TGFB1

Graphical network of the top 20 diseases related to Transient Arthritis:



Diseases related to Transient Arthritis

Symptoms & Phenotypes for Transient Arthritis

GenomeRNAi Phenotypes related to Transient Arthritis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.1 ALB CLEC7A PHB2 PRTN3 TGFB1 TNFRSF1B

MGI Mouse Phenotypes related to Transient Arthritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.96 ALB COMP F3 IL6 MBP PHB2
2 hematopoietic system MP:0005397 9.81 CLEC7A F3 IL1A IL6 MBP PRTN3
3 immune system MP:0005387 9.65 CLEC7A COMP F3 IL1A IL6 MBP
4 neoplasm MP:0002006 9.17 ALB F3 IL1A IL6 TGFB1 TNFRSF10A

Drugs & Therapeutics for Transient Arthritis

Search Clinical Trials , NIH Clinical Center for Transient Arthritis

Genetic Tests for Transient Arthritis

Anatomical Context for Transient Arthritis

MalaCards organs/tissues related to Transient Arthritis:

41
Skin, Bone, Lung, Brain, Kidney, Liver, Spinal Cord

Publications for Transient Arthritis

Articles related to Transient Arthritis:

# Title Authors Year
1
Activated partial thromboplastin time sensitivity to lupus anticoagulant in a patient with transient arthritis and lupus anticoagulant-hypoprothrombinemia syndrome. ( 25380995 )
2014
2
Rapid release of high mobility group box protein-1 (HMGB-1) in transient arthritis. ( 20483058 )
2010
3
Induction of transient arthritis by the adoptive transfer of a collagen II specific Th1 clone to HLA-DR4 (B1*0401) transgenic mice. ( 12367557 )
2002
4
Transient arthritis with positive tests for rheumatoid factor as presenting sign of shunt nephritis. ( 2015013 )
1991
5
Tenosynovitis and transient arthritis associated with Haemophilus influenzae type b bacteremia. ( 3261417 )
1988
6
Demonstration and characterization of a transient arthritis in rats following sensitization of synovial mast cells with antigen-specific IgE and parenteral challenge with specific antigen. ( 2457375 )
1988
7
Transient arthritis of the hip in children (a study of 74 cases). ( 6469611 )
1984
8
Transient arthritis after rubella vaccination. ( 5794817 )
1969
9
Acute transient arthritis of the adult hip. Its relation to rheumatoid arthritis and to "palindromic rheumatism". ( 14462616 )
1962

Variations for Transient Arthritis

Expression for Transient Arthritis

Search GEO for disease gene expression data for Transient Arthritis.

Pathways for Transient Arthritis

GO Terms for Transient Arthritis

Cellular components related to Transient Arthritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.76 ALB COMP F3 IL1A IL6 PRTN3
2 cell surface GO:0009986 9.72 F3 MBP PHB2 TGFB1 TNFRSF10A
3 extracellular region GO:0005576 9.65 ACAN ALB COMP F3 IL1A IL6
4 platelet alpha granule lumen GO:0031093 9.43 ALB SERPINA1 TGFB1
5 collagen-containing extracellular matrix GO:0062023 9.1 ACAN COMP F3 PRTN3 SERPINA1 TGFB1

Biological processes related to Transient Arthritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet degranulation GO:0002576 9.65 ALB SERPINA1 TGFB1
2 negative regulation of protein localization to plasma membrane GO:1903077 9.46 MRAP TGFB1
3 negative regulation of phagocytosis GO:0050765 9.43 PRTN3 TGFB1
4 connective tissue replacement involved in inflammatory response wound healing GO:0002248 9.4 IL1A TGFB1
5 mammary gland branching involved in thelarche GO:0060744 9.37 PHB2 TGFB1
6 inflammatory response GO:0006954 9.35 CLEC7A IL1A IL6 TGFB1 TNFRSF1B
7 extrinsic apoptotic signaling pathway GO:0097191 9.33 TGFB1 TNFRSF10A TNFRSF1B
8 positive regulation of exit from mitosis GO:0031536 9.32 PHB2 TGFB1
9 regulation of branching involved in mammary gland duct morphogenesis GO:0060762 9.26 PHB2 TGFB1
10 cytokine-mediated signaling pathway GO:0019221 9.1 F3 IL1A IL6 PRTN3 TGFB1 TNFRSF1B

Molecular functions related to Transient Arthritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.83 ACAN ALB CLEC7A COMP F3 IL1A
2 protease binding GO:0002020 9.02 COMP F3 MBP SERPINA1 TNFRSF10A

Sources for Transient Arthritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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