MCID: TRN014
MIFTS: 34

Transient Arthritis

Categories: Bone diseases, Skin diseases

Aliases & Classifications for Transient Arthritis

MalaCards integrated aliases for Transient Arthritis:

Name: Transient Arthritis 12 15 72

Classifications:



External Ids:

Disease Ontology 12 DOID:2092
ICD9CM 35 716.4 716.40
NCIt 50 C35761
SNOMED-CT 68 66191007
ICD10 33 M12.8
UMLS 72 C0152083 C3887596

Summaries for Transient Arthritis

MalaCards based summary : Transient Arthritis is related to tenosynovitis and arthritis. An important gene associated with Transient Arthritis is MRAP (Melanocortin 2 Receptor Accessory Protein), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Response to elevated platelet cytosolic Ca2+. Affiliated tissues include bone, b cells and t cells, and related phenotypes are cellular and hematopoietic system

Related Diseases for Transient Arthritis

Diseases in the Arthritis family:

Transient Arthritis

Diseases related to Transient Arthritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 85)
# Related Disease Score Top Affiliating Genes
1 tenosynovitis 30.0 TNFRSF1B MRAP COMP
2 arthritis 29.0 TNFRSF1B TGFB1 IL6 IL1A ACAN
3 palindromic rheumatism 28.8 TNFRSF1B TNFRSF10A PRTN3 MRAP
4 rheumatoid arthritis 27.2 TNFRSF1B TGFB1 PRTN3 IL6 IL1A COMP
5 bone chondrosarcoma 10.6 COMP ACAN
6 pyuria 10.5 MRAP ALB
7 meningovascular neurosyphilis 10.5 MBP ALB
8 geniculate herpes zoster 10.5 TNFRSF10A SERPINA1
9 cartilage disease 10.4 TNFRSF10A COMP ACAN
10 pustulosis of palm and sole 10.4 TNFRSF1B MRAP
11 pneumocystosis 10.4 CLEC7A CD40LG ALB
12 scleral disease 10.4 TNFRSF1B MRAP
13 gastritis, familial giant hypertrophic 10.4 SERPINA1 ALB
14 iritis 10.4 TNFRSF1B MRAP
15 orbital plasma cell granuloma 10.3 TNFRSF1B MRAP
16 constrictive pericarditis 10.3 SERPINA1 ALB
17 heparin-induced thrombocytopenia 10.3 F3 CD40LG
18 hepatic tuberculosis 10.3 SERPINA1 ALB
19 chronic graft versus host disease 10.3 IL1A ALB
20 leukoregulin 10.3 TGFB1 IL1A
21 juvenile ankylosing spondylitis 10.3 TNFRSF1B MRAP IL6
22 chondromalacia 10.3 TNFRSF1B TNFRSF10A COMP
23 keratoconjunctivitis sicca 10.2 IL6 IL1A ALB
24 uveal disease 10.2 TNFRSF1B MRAP IL6
25 exanthema subitum 10.2 TNFRSF1B IL6 CD40LG
26 proteasome-associated autoinflammatory syndrome 1 10.2 IL6 IL1A ALB
27 kidney hypertrophy 10.2 TGFB1 ALB
28 laryngitis 10.2 TGFB1 IL6
29 rhinoscleroma 10.2 TNFRSF1B SERPINA1
30 peripheral nervous system disease 10.1 MBP IL6 ALB
31 nervous system disease 10.1 MBP IL6 ALB
32 aortic valve disease 1 10.1 TGFB1 MRAP ACAN
33 carpal tunnel syndrome 10.1 TGFB1 IL6 ACAN
34 primary bacterial infectious disease 10.1 TNFRSF1B IL6 ALB
35 gingival disease 10.1 TGFB1 IL6 IL1A
36 gastrointestinal system disease 10.1 SERPINA1 IL6 ALB
37 fournier gangrene 10.1 F3 CD40LG ALB
38 gingival overgrowth 10.0 TGFB1 IL6 IL1A
39 guillain-barre syndrome 10.0 TNFRSF1B MBP ALB
40 euthyroid sick syndrome 10.0 IL6 ALB
41 catastrophic antiphospholipid syndrome 10.0 F3 CD40LG
42 end stage renal failure 10.0 TGFB1 IL6 ALB
43 meningoencephalitis 10.0 MBP IL6 CD40LG ALB
44 interstitial lung disease 10.0 TGFB1 IL6 IL1A
45 pneumoconiosis 10.0 TGFB1 SERPINA1 IL6
46 giant hemangioma 10.0 TGFB1 F3
47 posterior urethral valves 10.0 TGFB1 IL6
48 posterior scleritis 10.0 TNFRSF10A PRTN3 MRAP
49 dengue hemorrhagic fever 9.9 IL6 F3 ALB
50 peripheral vascular disease 9.9 IL6 F3 ALB

Graphical network of the top 20 diseases related to Transient Arthritis:



Diseases related to Transient Arthritis

Symptoms & Phenotypes for Transient Arthritis

MGI Mouse Phenotypes related to Transient Arthritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.02 ALB CD40LG COMP F3 IL6 MBP
2 hematopoietic system MP:0005397 9.96 CD40LG CLEC7A F3 IL1A IL6 MBP
3 homeostasis/metabolism MP:0005376 9.9 ALB CD40LG CLEC7A COMP F3 IL1A
4 immune system MP:0005387 9.7 CD40LG CLEC7A COMP F3 IL1A IL6
5 neoplasm MP:0002006 9.17 ALB F3 IL1A IL6 TGFB1 TNFRSF10A

Drugs & Therapeutics for Transient Arthritis

Search Clinical Trials , NIH Clinical Center for Transient Arthritis

Genetic Tests for Transient Arthritis

Anatomical Context for Transient Arthritis

MalaCards organs/tissues related to Transient Arthritis:

41
Bone, B Cells, T Cells, Lung, Testes, Bone Marrow

Publications for Transient Arthritis

Articles related to Transient Arthritis:

(show top 50) (show all 64)
# Title Authors PMID Year
1
Does early seronegative arthritis develop into rheumatoid arthritis? A 10-year observational study. 38
29998832 2019
2
Evaluation of a pressure sensitive walkway for objective gait analysis in normal and arthritic domestic ducks (Cairina moschata domestica). 38
31344125 2019
3
Diagnosis of Systemic Lupus Erythematosus in a Polynesian Male with a History of Rheumatic Fever: A Case Report and Literature Review. 38
30693131 2018
4
Local cryotherapy improves adjuvant-induced arthritis through down-regulation of IL-6 / IL-17 pathway but independently of TNF╬▒. 38
28759646 2017
5
Activated partial thromboplastin time sensitivity to lupus anticoagulant in a patient with transient arthritis and lupus anticoagulant-hypoprothrombinemia syndrome. 38
25380995 2015
6
Lyme disease with effusion either in hip or knee in children from Podlaskie region treated in clinic in 2004-2010. 38
25394303 2014
7
Differences in MRI findings between subgroups of recent-onset childhood arthritis. 38
21136049 2011
8
Rapid release of high mobility group box protein-1 (HMGB-1) in transient arthritis. 38
20483058 2010
9
Dissecting the contribution of innate and antigen-specific pathways to the breach of self-tolerance observed in a murine model of arthritis. 38
18635595 2009
10
Henoch-Schönlein purpura: a long-term prospective study in Greek children. 38
18703982 2008
11
Recent-onset childhood arthritis--association with Streptococcus pyogenes in a population-based study. 38
18420659 2008
12
Incidence and characteristics of arthritis in Norwegian children: a population-based study. 38
18227193 2008
13
A role for fungal {beta}-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice. 38
15781585 2005
14
Antigen-specific B cells are required as APCs and autoantibody-producing cells for induction of severe autoimmune arthritis. 38
15749919 2005
15
A mouse herpesvirus induces relapse of experimental autoimmune arthritis by infection of the inflammatory target tissue. 38
15470069 2004
16
Bone marrow cells carrying the env-pX transgene play a role in the severity but not prolongation of arthritis in human T-cell leukaemia virus type-I transgenic rats: a possible role of articular tissues carrying the transgene in the prolongation of arthritis. 38
15312124 2004
17
A pruritic linear urticarial rash, fever, and systemic inflammatory disease in five adolescents: adult-onset still disease or systemic juvenile idiopathic arthritis sine arthritis? 38
15461768 2004
18
Inducing experimental arthritis and breaking self-tolerance to joint-specific antigens with trackable, ovalbumin-specific T cells. 38
15210769 2004
19
[Exotic viral arthritis: role of alphavirus]. 38
15224565 2004
20
[The use of real-time polymerase chain reaction and enzyme immunoassay for the diagnosis of acute parvovirus B19 infections in immunosuppressed patients]. 38
14748265 2003
21
Long term follow up of serostatus after maternofetal parvovirus B19 infection. 38
12598382 2003
22
Induction of transient arthritis by the adoptive transfer of a collagen II specific Th1 clone to HLA-DR4 (B1*0401) transgenic mice. 38
12367557 2002
23
Severity of group B streptococcal arthritis is correlated with beta-hemolysin expression. 38
10950777 2000
24
Normalization of creatine kinase level during arthritis in a patient with Becker muscular dystrophy. 38
9921868 1999
25
Chronic arthritis and carpo:metacarpal ratio in Japanese patients with adult Still's disease. 38
9858437 1998
26
Common commercial cosmetic products induce arthritis in the DA rat. 38
9417771 1998
27
Cartilage macromolecules in knee joint synovial fluid. Markers of the disease course in patients with acute oligoarthritis. 38
9496157 1997
28
Long-term prognosis of reactive salmonella arthritis. 38
9370874 1997
29
Risk of chronic arthropathy among women after rubella vaccination. Vaccine Safety Datalink Team. 38
9268275 1997
30
A case of prolonged human parvovirus B19 DNA-emia associated with polyclonal B cell activation. 38
8840543 1996
31
Preferential induction of septic arthritis and mortality by superantigen-producing staphylococci. 38
7558340 1995
32
Specific and long-lasting protection from collagen-induced arthritis and oil-induced arthritis in DA rats by administration of immunogens. 38
7543214 1995
33
Association between human parvovirus B19 infection and arthritis. 38
7632094 1995
34
Percutaneous exposure of adjuvant oil causes arthritis in DA rats. 38
8187335 1994
35
Cell migration studies in the adoptive transfer of adjuvant arthritis in the Lewis rat. 38
8206515 1994
36
[Polyarthritis in 4 patients treated with intravesical BCG-therapy for carcinoma of the bladder]. 38
8136810 1993
37
Human parvovirus B19 and rheumatoid arthritis. 38
1486749 1992
38
Acceleration of onset of collagen-induced arthritis by intra-articular injection of tumour necrosis factor or transforming growth factor-beta. 38
1638767 1992
39
Transient arthritis with positive tests for rheumatoid factor as presenting sign of shunt nephritis. 38
2015013 1991
40
[The protease-antiprotease system in pathogenesis of transient arthritis of a single joint in children]. 38
1369947 1990
41
Clinical, HLA, and roentgenological follow up study of patients with juvenile arthritis: comparison between the long term outcome of transient and persistent arthritis in children. 38
2531995 1989
42
Lyme disease: musculoskeletal manifestations. 38
2685923 1989
43
Demonstration and characterization of a transient arthritis in rats following sensitization of synovial mast cells with antigen-specific IgE and parenteral challenge with specific antigen. 38
2457375 1988
44
Tenosynovitis and transient arthritis associated with Haemophilus influenzae type b bacteremia. 38
3261417 1988
45
Exacerbation of arthritis by IL-1 in rat joints previously injured by peptidoglycan-polysaccharide. 38
3283241 1988
46
The immune response of guinea-pigs to type II collagen: poor cross-reactivity with homologous type II collagen accounts for resistance to collagen-induced arthritis. 38
3366471 1988
47
Infections and related risk factors of arthritis in children. A case-control study. 38
3602947 1987
48
Routine analysis of synovial fluid cells is of value in the differential diagnosis of arthritis in children. 38
3560094 1986
49
Incidence of arthritis in urban Finnish children. A prospective study. 38
3768057 1986
50
Isolation and identification of a South African lentivirus from jaagsiekte lungs. 38
3008059 1986

Variations for Transient Arthritis

Expression for Transient Arthritis

Search GEO for disease gene expression data for Transient Arthritis.

Pathways for Transient Arthritis

Pathways related to Transient Arthritis according to GeneCards Suite gene sharing:

(show all 21)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.19 TNFRSF1B TGFB1 PRTN3 IL6 IL1A CD40LG
2
Show member pathways
13.15 TNFRSF10A TGFB1 SERPINA1 PRTN3 F3 ALB
3
Show member pathways
13.13 TNFRSF1B TNFRSF10A TGFB1 IL6 IL1A CD40LG
4
Show member pathways
12.71 TNFRSF1B TGFB1 IL6 IL1A CD40LG
5
Show member pathways
12.5 TNFRSF1B TGFB1 IL6 IL1A CD40LG
6
Show member pathways
12.38 TGFB1 IL6 IL1A CD40LG
7 12.01 TGFB1 IL6 IL1A CLEC7A
8
Show member pathways
11.81 TNFRSF1B TNFRSF10A TGFB1 IL6 IL1A
9 11.79 TGFB1 SERPINA1 IL6 ALB
10 11.78 TGFB1 IL6 IL1A
11 11.7 TGFB1 IL6 IL1A
12 11.61 TNFRSF1B TGFB1 IL6 IL1A
13
Show member pathways
11.5 IL6 IL1A CD40LG
14 11.49 TGFB1 SERPINA1 IL6
15 11.46 TGFB1 IL6 IL1A F3
16 11.43 TGFB1 COMP ACAN
17 11.3 TNFRSF1B IL6 IL1A
18 11.1 TGFB1 MBP IL6 IL1A ACAN
19 10.96 TGFB1 IL6 IL1A
20 10.95 TGFB1 IL6 COMP CD40LG
21 10.85 TGFB1 IL6 IL1A CD40LG ACAN

GO Terms for Transient Arthritis

Cellular components related to Transient Arthritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.81 TGFB1 SERPINA1 PRTN3 IL6 IL1A F3
2 cell surface GO:0009986 9.72 TNFRSF10A TGFB1 MBP F3 CD40LG
3 platelet alpha granule lumen GO:0031093 9.43 TGFB1 SERPINA1 ALB
4 collagen-containing extracellular matrix GO:0062023 9.43 TGFB1 SERPINA1 PRTN3 F3 COMP ACAN
5 extracellular region GO:0005576 9.36 TNFRSF1B TGFB1 SERPINA1 PRTN3 IL6 IL1A

Biological processes related to Transient Arthritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.72 TNFRSF1B MBP IL6 IL1A CD40LG
2 platelet degranulation GO:0002576 9.61 TGFB1 SERPINA1 ALB
3 inflammatory response GO:0006954 9.43 TNFRSF1B TGFB1 IL6 IL1A CLEC7A CD40LG
4 negative regulation of protein localization to plasma membrane GO:1903077 9.4 TGFB1 MRAP
5 negative regulation of phagocytosis GO:0050765 9.37 TGFB1 PRTN3
6 extrinsic apoptotic signaling pathway GO:0097191 9.33 TNFRSF1B TNFRSF10A TGFB1
7 connective tissue replacement involved in inflammatory response wound healing GO:0002248 9.26 TGFB1 IL1A
8 cytokine-mediated signaling pathway GO:0019221 9.1 TNFRSF1B TGFB1 PRTN3 IL6 IL1A F3

Molecular functions related to Transient Arthritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.83 TNFRSF1B TNFRSF10A TGFB1 SERPINA1 PRTN3 MRAP
2 cytokine activity GO:0005125 9.46 TGFB1 IL6 IL1A CD40LG
3 protease binding GO:0002020 9.02 TNFRSF10A SERPINA1 MBP F3 COMP

Sources for Transient Arthritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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