TPHA
MCID: TRN053
MIFTS: 25

Transient Pseudohypoaldosteronism (TPHA)

Categories: Blood diseases, Cardiovascular diseases, Endocrine diseases, Genetic diseases, Metabolic diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Transient Pseudohypoaldosteronism

MalaCards integrated aliases for Transient Pseudohypoaldosteronism:

Name: Transient Pseudohypoaldosteronism 59
Tpha 59

Classifications:

Orphanet: 59  
Rare renal diseases


External Ids:

ICD10 via Orphanet 34 N15.8
Orphanet 59 ORPHA93164

Summaries for Transient Pseudohypoaldosteronism

MalaCards based summary : Transient Pseudohypoaldosteronism, also known as tpha, is related to syphilis and pseudohypoaldosteronism. The drugs Penicillin G and Azithromycin have been mentioned in the context of this disorder. Affiliated tissues include testes, whole blood and liver.

Related Diseases for Transient Pseudohypoaldosteronism

Graphical network of the top 20 diseases related to Transient Pseudohypoaldosteronism:



Diseases related to Transient Pseudohypoaldosteronism

Symptoms & Phenotypes for Transient Pseudohypoaldosteronism

Drugs & Therapeutics for Transient Pseudohypoaldosteronism

Drugs for Transient Pseudohypoaldosteronism (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 16)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Penicillin G Approved, Vet_approved Phase 3 61-33-6 5904
2
Azithromycin Approved Phase 3 83905-01-5 447043 55185
3
carbamide peroxide Approved Phase 3 124-43-6
4
Procaine Approved, Investigational, Vet_approved Phase 3 59-46-1 4914
5 Anti-Bacterial Agents Phase 3
6 Antibiotics, Antitubercular Phase 3
7 penicillins Phase 3
8 Anti-Infective Agents Phase 3
9 Penicillin G Procaine Phase 3
10 Penicillin G Benzathine Phase 3
11 Dermatologic Agents Phase 3
12
Sargramostim Approved, Investigational Phase 2 83869-56-1, 123774-72-1
13
Lenograstim Approved, Investigational Phase 2 135968-09-1
14 Adjuvants, Immunologic Phase 2
15 Immunologic Factors Phase 2
16 Liver Extracts

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Single-dose Azithromycin Versus Penicillin G Benzathine for the Treatment of Yaws in Children Completed NCT01382004 Phase 3 Penicillin-G-benzathine;Azithromycin
2 Effect of WHO-yaws Elimination Strategy in Lihir Island, Papua New Guinea Completed NCT01955252 Phase 3 Azithromycin
3 A Open-label, No-treatment-controlled, Parallel, Pilot Phase Ⅱ Study to Evaluate the Efficacy and Safety/Tolerability Profiles of G-CSF in Subjects With Mild to Moderate Alzheimer's Disease Completed NCT03656042 Phase 2 Filgrastim (75mcg/0.3ml)
4 Xijing HOSPITAL, Fourth Military Medical University, China Completed NCT00921648
5 Evaluation of a Rapid Dual Point-of-care Assay for Targeting Antibiotic Treatment for Yaws Eradication: a Prospective Descriptive Study Completed NCT01841203
6 Regional Multicenter Study to Evaluate Tolerability and Efficacy of TAF/FTC/RPV Combination (ODEFSEY ®) in Prevention of Sexual or Blood Exposure to HIV Not yet recruiting NCT03451032
7 2000 HIV Human Functional Genomics Partnership Program Not yet recruiting NCT03994835
8 Qualitative Evaluation of the DPP Syphilis Screen and Confirm Rapid Test to Detect the Presence of Antibodies Against Non-Treponemal and Treponema Pallidum Antigens in Fingerstick Whole Blood, Venous Whole Blood, Serum and Plasma Specimens. Withdrawn NCT01543295

Search NIH Clinical Center for Transient Pseudohypoaldosteronism

Genetic Tests for Transient Pseudohypoaldosteronism

Anatomical Context for Transient Pseudohypoaldosteronism

MalaCards organs/tissues related to Transient Pseudohypoaldosteronism:

41
Testes, Whole Blood, Liver, T Cells, Bone, Skin, Eye

Publications for Transient Pseudohypoaldosteronism

Articles related to Transient Pseudohypoaldosteronism:

(show top 50) (show all 649)
# Title Authors PMID Year
1
Performance of a Dual Human Immunodeficiency Virus/Syphilis Rapid Test Compared With Conventional Serological Testing for Syphilis and Human Immunodeficiency Virus in a Laboratory Setting: Results From the Zimbabwe STI Etiology Study. 38
31181033 2019
2
Neuroretinitis Syphilis in Human Immunodeficiency Virus-Infected Patient. 38
31406542 2019
3
Clinical features of syphilitic myelitis with longitudinally extensive myelopathy on spinal magnetic resonance imaging. 38
31236392 2019
4
Transient pseudohypoaldosteronism: a potentially severe condition affecting infants with urinary tract malformation. 38
30962012 2019
5
[SOME PECULIARITIES OF SYPHILIS MORPHOLOGY AND PATHOLOGY (REVIEW)]. 38
31101787 2019
6
Limited efficacy of nontreponemal test combined with treponemal test in the initial syphilis screening algorithm. 38
30570479 2019
7
Performance evaluation of nine different syphilis serological tests in comparison with the FTA-abs test. 38
30138611 2019
8
Genital Herpes Zoster as Possible Indicator of HIV Infection. 38
30665486 2018
9
Evaluation of Treponema pallidum Hemagglutination Assay among Varying Titers of the Venereal Disease Research Laboratory Test. 38
30504976 2018
10
An infant presenting with failure to thrive and hyperkalaemia owing to transient pseudohypoaldosteronism: case report. 38
28557682 2018
11
The prevalence of transfusion-transmitted infections and nucleic acid testing among blood donors in Majmaah, Saudi Arabia. 38
29703711 2018
12
Features of syphilis seropositive pregnant women raising alarms in Hungary, 2013-2016. 38
30053759 2018
13
[Transient Pseudohypoaldosteronism - an Important Differential Diagnosis to Congenital Adrenal Hyperplasia]. 38
29564839 2018
14
LATE DIAGNOSIS OF CONGENITAL SYPHILIS: A RECURRING REALITY IN WOMEN AND CHILDREN HEALTH CARE IN BRAZIL. 38
30066818 2018
15
Unusual Manifestations of Secondary Syphilis: Case Presentations. 38
29989879 2018
16
Serological Diagnosis of Syphilis: Preliminary Study Searching for an Algorhitm in Turkey. 38
29989871 2018
17
[Multiple Spinal Intradural and Extradural Syphilis Granuloma Mimicking Lumbar Dumbbell Type Neurinoma:A Case Report]. 38
29794319 2018
18
Stroke and syphilis: A retrospective study of 53 patients. 38
29631855 2018
19
Trends and Predictors of Syphilis Prevalence in the General Population: Global Pooled Analyses of 1103 Prevalence Measures Including 136 Million Syphilis Tests. 38
29136161 2018
20
High seroprevalence of syphilis infection among pregnant women in Yiregalem hospital southern Ethiopia. 38
29510664 2018
21
Transient Pseudohypoaldosteronism Caused by Intestinal Abnormalities. 38
29237184 2018
22
Correlation between Venereal Diseases Research Laboratory titers and CD4 T-lymphocyte count determined by flow cytometry in HIV-infected adults: A 5-year study. 38
30187020 2018
23
A retrospective study of the prevalence and outcomes of syphilis in pregnancy in a 5-year period. 38
28980302 2018
24
Clinic-based evaluation study of the diagnostic accuracy of a dual rapid test for the screening of HIV and syphilis in pregnant women in Nigeria. 38
29990336 2018
25
Hidden dangers-prevalence of blood borne pathogens, hepatitis B, C, HIV and syphilis, among blood donors in Sierra Leone in 2016: opportunities for improvement: a retrospective, cross-sectional study. 38
30167071 2018
26
Comparison of RPR and ELISA with TPHA for the Diagnosis of Syphilis: Implication for Updating Syphilis Point-of-Care Tests in Ethiopia. 38
30069486 2018
27
Rapid Response to Syphilis Outbreak among Female Sex Workers. 38
29184321 2017
28
The big imitator strikes again: a case report of neurosyphilis in a patient with newly diagnosed HIV. 38
28220718 2017
29
Syphilis testing practices in the Americas. 38
28653418 2017
30
Congenital Jejunal Membrane Causing Transient Pseudohypoaldosteronism and Hypoprothrombinemia in a 7-Week-Old Infant. 38
28806843 2017
31
Tertiary syphilis in the lumbar spine: a case report. 38
28738852 2017
32
Cerebrospinal Fluid Treponema pallidum Particle Agglutination Assay for Neurosyphilis Diagnosis. 38
28381602 2017
33
Non-malarial infectious diseases of antenatal care in pregnant women in Franceville, Gabon. 38
28606185 2017
34
Transient pseudohypoaldosteronism in infancy secondary to urinary tract infection. 38
28233358 2017
35
Gastric syphilis. 38
28507905 2017
36
Prevalence and risk factors associated with sexually transmitted infections (STIs) among women of reproductive age in Swaziland. 38
28559923 2017
37
Syphilis and HIV infections among pregnant women attending antenatal clinics in Republic of Congo. 38
29138654 2017
38
[Skin and mucosal erosions revealing secondary syphilis with otologic and eye disorders]. 38
27646571 2016
39
[The role of reflectance confocal microscopy in the diagnosis of secondary syphilis of the vulva and anus: A first case report]. 38
27567281 2016
40
Utility of Laboratory Diagnosis for Confirmation of the Syndromic Case Management in Married Indian Women with Vaginal Discharge. 38
27833516 2016
41
Clinical Evaluation of 2 Point-of-Care Lateral Flow Tests for the Diagnosis of Syphilis. 38
27631356 2016
42
Sexually transmitted infections and HIV in self reporting men who have sex with men: A two-year study from India. 38
26776704 2016
43
Secondary or Transient Pseudohypoaldosteronism Associated With Urinary Tract Anomaly and Urinary Infection: A Case Report. 38
27516976 2016
44
Congenital primary adrenal insufficiency and selective aldosterone defects presenting as salt-wasting in infancy: a single center 10-year experience. 38
27485500 2016
45
Reducing risks of Transfusion-transmitted infections in a resource-limited hospital-based blood bank: the case of the Yaoundé University Teaching Hospital, Cameroon. 38
28484511 2016
46
Syphilis detection: evaluation of serological screening and pilot reverse confirmatory assay algorithm in blood donors. 38
26068964 2016
47
Clinical and neuropsychological characteristics of general paresis misdiagnosed as primary psychiatric disease. 38
27400713 2016
48
Evaluation of Multiplex-Based Antibody Testing for Use in Large-Scale Surveillance for Yaws: a Comparative Study. 38
26962086 2016
49
Performances of TPHA, RPR and rapid immuno-chromatographic test in syphilis screening among blood donors at the university teaching hospital of Yaoundé, Cameroon. 38
26655838 2016
50
Seroepidemiology of HIV, syphilis and hepatitis B and C viruses among blood donors in Bangui, Central African Republic. 38
27412978 2016

Variations for Transient Pseudohypoaldosteronism

Expression for Transient Pseudohypoaldosteronism

Search GEO for disease gene expression data for Transient Pseudohypoaldosteronism.

Pathways for Transient Pseudohypoaldosteronism

GO Terms for Transient Pseudohypoaldosteronism

Sources for Transient Pseudohypoaldosteronism

3 CDC
7 CNVD
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10 dbSNP
11 DGIdb
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49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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