MCID: TRN019
MIFTS: 27

Transitional Papilloma

Categories: Cancer diseases

Aliases & Classifications for Transitional Papilloma

MalaCards integrated aliases for Transitional Papilloma:

Name: Transitional Papilloma 12 15
Transitional Cell Papilloma, Benign 12 74
Transitional Cell Papilloma 12 17

Classifications:



External Ids:

Disease Ontology 12 DOID:2670
NCIt 51 C4115
SNOMED-CT 69 44342003 45083001
UMLS 74 C0334266

Summaries for Transitional Papilloma

MalaCards based summary : Transitional Papilloma, also known as transitional cell papilloma, benign, is related to bladder transitional cell papilloma and inverted transitional papilloma. An important gene associated with Transitional Papilloma is KRT13 (Keratin 13), and among its related pathways/superpathways are Circadian entrainment and Cytoskeletal Signaling. Affiliated tissues include cervix and kidney, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Transitional Papilloma

Diseases related to Transitional Papilloma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
# Related Disease Score Top Affiliating Genes
1 bladder transitional cell papilloma 12.5
2 inverted transitional papilloma 12.3
3 papilloma 10.0
4 ovarian brenner tumor 9.9 KRT13 KRT18
5 hydronephrosis 9.9
6 leiomyoma 9.9
7 bladder leiomyoma 9.9
8 squamous cell papilloma 9.8
9 basaloid squamous cell carcinoma 9.7 KRT13 KRT17
10 intraneural perineurioma 9.6 KRT13 KRT18 SOX10
11 primary cutaneous amyloidosis 9.6 KRT17 KRT18
12 polycystic liver disease 1 with or without kidney cysts 9.5 KRT13 KRT17

Graphical network of the top 20 diseases related to Transitional Papilloma:



Diseases related to Transitional Papilloma

Symptoms & Phenotypes for Transitional Papilloma

GenomeRNAi Phenotypes related to Transitional Papilloma according to GeneCards Suite gene sharing:

27 (show all 25)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-154 9.76 KRT18
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-17 9.76 KRT18 SOX10
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-18 9.76 SOX10
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.76 KRT18
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.76 KRT18
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.76 KRT18
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.76 SOX10
8 Increased shRNA abundance (Z-score > 2) GR00366-A-107 9.58 KRT17
9 Increased shRNA abundance (Z-score > 2) GR00366-A-110 9.58 KRT13
10 Increased shRNA abundance (Z-score > 2) GR00366-A-116 9.58 KRT13
11 Increased shRNA abundance (Z-score > 2) GR00366-A-166 9.58 KRT17
12 Increased shRNA abundance (Z-score > 2) GR00366-A-174 9.58 KRT17
13 Increased shRNA abundance (Z-score > 2) GR00366-A-189 9.58 KRT13 KRT17
14 Increased shRNA abundance (Z-score > 2) GR00366-A-196 9.58 KRT17
15 Increased shRNA abundance (Z-score > 2) GR00366-A-198 9.58 KRT17
16 Increased shRNA abundance (Z-score > 2) GR00366-A-199 9.58 KRT17
17 Increased shRNA abundance (Z-score > 2) GR00366-A-21 9.58 KRT13
18 Increased shRNA abundance (Z-score > 2) GR00366-A-30 9.58 KRT13
19 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.58 KRT17
20 Increased shRNA abundance (Z-score > 2) GR00366-A-45 9.58 KRT17
21 Increased shRNA abundance (Z-score > 2) GR00366-A-46 9.58 KRT17
22 Increased shRNA abundance (Z-score > 2) GR00366-A-49 9.58 KRT17
23 Increased shRNA abundance (Z-score > 2) GR00366-A-50 9.58 KRT13
24 Increased shRNA abundance (Z-score > 2) GR00366-A-81 9.58 KRT13
25 Increased cell death HMECs cells GR00103-A-0 9.13 KRT13 KRT18 SOX10

Drugs & Therapeutics for Transitional Papilloma

Search Clinical Trials , NIH Clinical Center for Transitional Papilloma

Genetic Tests for Transitional Papilloma

Anatomical Context for Transitional Papilloma

MalaCards organs/tissues related to Transitional Papilloma:

42
Cervix, Kidney

Publications for Transitional Papilloma

Articles related to Transitional Papilloma:

(show all 17)
# Title Authors Year
1
Accidentally diagnosed transitional cell papilloma of the lacrimal sac. ( 28860918 )
2017
2
Hematuria and transitional cell papilloma of the renal pelvis treated via unilateral nephrectomy in an alpaca. ( 18412535 )
2008
3
Transitional cell papilloma and leiomyoma of the urinary bladder in two goats. ( 17220524 )
2007
4
Silibinin activates p53-caspase 2 pathway and causes caspase-mediated cleavage of Cip1/p21 in apoptosis induction in bladder transitional-cell papilloma RT4 cells: evidence for a regulatory loop between p53 and caspase 2. ( 16777994 )
2006
5
Transitional cell papilloma of the bladder in a child: a case report and review of literature. ( 18947598 )
2006
6
Silibinin down-regulates survivin protein and mRNA expression and causes caspases activation and apoptosis in human bladder transitional-cell papilloma RT4 cells. ( 14651997 )
2003
7
Transitional cell papilloma of the penis associated with human papilloma virus infection. Report of two cases. ( 12728314 )
2003
8
Urothelial (transitional cell) papilloma of the urinary bladder: a clinicopathologic study of 26 cases. ( 12861056 )
2003
9
Inverted transitional cell papilloma of the uterine cervix. ( 11842379 )
2002
10
Urinary bladder transitional cell papilloma in a shorthorn heifer. ( 11062838 )
2000
11
Unusual histological type of oral papilloma, mimicking sinonasal tract papilloma (transitional cell papilloma) ( 10922174 )
2000
12
Transitional cell papilloma in the fossa navicularis is positive for human papillomavirus. ( 9624566 )
1998
13
Accumulation of p53 protein in inverted transitional cell papilloma of the urinary bladder. ( 16696044 )
1996
14
[Inverted transitional-cell papilloma: the expression of the Ki-67 nuclear antigen as a prognostic factor]. ( 8554393 )
1995
15
Transitional papilloma of the middle ear. ( 1527461 )
1992
16
Transitional papilloma of the nasal cavity and paranasal sinuses. Clinical course, viral etiology and malignant transformation. ( 2554233 )
1989
17
Transitional cell papilloma of the ureter causing hydronephrosis in a child. ( 6626907 )
1983

Variations for Transitional Papilloma

Expression for Transitional Papilloma

Search GEO for disease gene expression data for Transitional Papilloma.

Pathways for Transitional Papilloma

GO Terms for Transitional Papilloma

Cellular components related to Transitional Papilloma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.67 KRT13 KRT17 KRT18 NDRG1
2 cell-cell adherens junction GO:0005913 9.32 KRT18 NDRG1
3 keratin filament GO:0045095 9.26 KRT13 KRT18
4 cell periphery GO:0071944 9.16 KRT17 KRT18
5 intermediate filament cytoskeleton GO:0045111 8.96 KRT13 KRT17
6 intermediate filament GO:0005882 8.8 KRT13 KRT17 KRT18

Biological processes related to Transitional Papilloma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoskeleton organization GO:0007010 9.26 KRT13 KRT17
2 anatomical structure morphogenesis GO:0009653 9.16 KRT18 SOX10
3 keratinization GO:0031424 9.13 KRT13 KRT17 KRT18
4 cornification GO:0070268 8.8 KRT13 KRT17 KRT18

Molecular functions related to Transitional Papilloma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 8.8 KRT13 KRT17 KRT18

Sources for Transitional Papilloma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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