MCID: TRN019
MIFTS: 24

Transitional Papilloma

Categories: Cancer diseases

Aliases & Classifications for Transitional Papilloma

MalaCards integrated aliases for Transitional Papilloma:

Name: Transitional Papilloma 12 15
Transitional Cell Papilloma, Benign 12 73
Transitional Cell Papilloma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2670
NCIt 50 C4115
SNOMED-CT 68 44342003 45083001
UMLS 73 C0334266

Summaries for Transitional Papilloma

MalaCards based summary : Transitional Papilloma, also known as transitional cell papilloma, benign, is related to bladder transitional cell papilloma and inverted transitional papilloma. An important gene associated with Transitional Papilloma is KRT13 (Keratin 13), and among its related pathways/superpathways are Circadian entrainment and Cytoskeletal Signaling. Affiliated tissues include kidney and liver, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Transitional Papilloma

Diseases related to Transitional Papilloma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 bladder transitional cell papilloma 12.5
2 inverted transitional papilloma 12.3
3 papilloma 9.9
4 ovarian brenner tumor 9.9 KRT13 KRT18
5 leiomyoma 9.9
6 bladder leiomyoma 9.9
7 basaloid squamous cell carcinoma 9.8 KRT13 KRT17
8 intraneural perineurioma 9.8 KRT13 KRT18 SOX10
9 primary cutaneous amyloidosis 9.8 KRT17 KRT18
10 polycystic liver disease 1 with or without kidney cysts 9.7 KRT13 KRT17

Graphical network of the top 20 diseases related to Transitional Papilloma:



Diseases related to Transitional Papilloma

Symptoms & Phenotypes for Transitional Papilloma

GenomeRNAi Phenotypes related to Transitional Papilloma according to GeneCards Suite gene sharing:

26 (show all 24)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-154 9.76 KRT18
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-17 9.76 KRT18 SOX10
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-18 9.76 SOX10
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.76 KRT18
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.76 KRT18
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.76 KRT18
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.76 SOX10
8 Increased shRNA abundance (Z-score > 2) GR00366-A-107 9.55 KRT17
9 Increased shRNA abundance (Z-score > 2) GR00366-A-110 9.55 KRT13
10 Increased shRNA abundance (Z-score > 2) GR00366-A-166 9.55 KRT17
11 Increased shRNA abundance (Z-score > 2) GR00366-A-174 9.55 KRT17
12 Increased shRNA abundance (Z-score > 2) GR00366-A-189 9.55 KRT13 KRT17
13 Increased shRNA abundance (Z-score > 2) GR00366-A-196 9.55 KRT17
14 Increased shRNA abundance (Z-score > 2) GR00366-A-198 9.55 KRT17
15 Increased shRNA abundance (Z-score > 2) GR00366-A-199 9.55 KRT17
16 Increased shRNA abundance (Z-score > 2) GR00366-A-21 9.55 KRT13
17 Increased shRNA abundance (Z-score > 2) GR00366-A-30 9.55 KRT13
18 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.55 KRT17
19 Increased shRNA abundance (Z-score > 2) GR00366-A-45 9.55 KRT17
20 Increased shRNA abundance (Z-score > 2) GR00366-A-46 9.55 KRT17
21 Increased shRNA abundance (Z-score > 2) GR00366-A-49 9.55 KRT17
22 Increased shRNA abundance (Z-score > 2) GR00366-A-50 9.55 KRT13
23 Increased shRNA abundance (Z-score > 2) GR00366-A-81 9.55 KRT13
24 Increased cell death HMECs cells GR00103-A-0 9.13 KRT13 KRT18 SOX10

Drugs & Therapeutics for Transitional Papilloma

Search Clinical Trials , NIH Clinical Center for Transitional Papilloma

Genetic Tests for Transitional Papilloma

Anatomical Context for Transitional Papilloma

MalaCards organs/tissues related to Transitional Papilloma:

41
Kidney, Liver

Publications for Transitional Papilloma

Articles related to Transitional Papilloma:

# Title Authors Year
1
Transitional papilloma of the middle ear. ( 1527461 )
1992
2
Transitional papilloma of the nasal cavity and paranasal sinuses. Clinical course, viral etiology and malignant transformation. ( 2554233 )
1989

Variations for Transitional Papilloma

Expression for Transitional Papilloma

Search GEO for disease gene expression data for Transitional Papilloma.

Pathways for Transitional Papilloma

GO Terms for Transitional Papilloma

Cellular components related to Transitional Papilloma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.67 KRT13 KRT17 KRT18 NDRG1
2 cell-cell adherens junction GO:0005913 9.32 KRT18 NDRG1
3 keratin filament GO:0045095 9.26 KRT13 KRT18
4 cell periphery GO:0071944 9.16 KRT17 KRT18
5 intermediate filament cytoskeleton GO:0045111 8.96 KRT13 KRT17
6 intermediate filament GO:0005882 8.8 KRT13 KRT17 KRT18

Biological processes related to Transitional Papilloma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoskeleton organization GO:0007010 9.26 KRT13 KRT17
2 anatomical structure morphogenesis GO:0009653 9.16 KRT18 SOX10
3 keratinization GO:0031424 9.13 KRT13 KRT17 KRT18
4 cornification GO:0070268 8.8 KRT13 KRT17 KRT18

Molecular functions related to Transitional Papilloma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 8.8 KRT13 KRT17 KRT18

Sources for Transitional Papilloma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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