MCID: TRN003
MIFTS: 34

Transverse Colon Cancer

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Transverse Colon Cancer

MalaCards integrated aliases for Transverse Colon Cancer:

Name: Transverse Colon Cancer 12 15
Malignant Neoplasm of Transverse Colon 74
Malignant Tumor of Transverse Colon 12
Ca Transverse Colon 12

Classifications:



External Ids:

Disease Ontology 12 DOID:261
ICD9CM 36 153.1
SNOMED-CT 69 94105000
ICD10 34 C18.4
UMLS 74 C0153434

Summaries for Transverse Colon Cancer

MalaCards based summary : Transverse Colon Cancer, also known as malignant neoplasm of transverse colon, is related to appendix adenocarcinoma and krukenberg carcinoma. An important gene associated with Transverse Colon Cancer is KRT20 (Keratin 20), and among its related pathways/superpathways are Developmental Biology and Keratinization. The drugs Fluorouracil and Cola have been mentioned in the context of this disorder. Affiliated tissues include colon, appendix and lymph node.

Related Diseases for Transverse Colon Cancer

Diseases related to Transverse Colon Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 103)
# Related Disease Score Top Affiliating Genes
1 appendix adenocarcinoma 30.0 KRT20 KRT7
2 krukenberg carcinoma 30.0 KRT20 KRT7
3 mucinous adenocarcinoma 30.0 KRT20 KRT7
4 colorectal cancer 10.5
5 cystic basal cell carcinoma 10.1 KRT20 KRT7
6 basal cell carcinoma 10.1 KRT20 KRT7
7 seminal vesicle adenocarcinoma 10.1 KRT20 KRT7
8 malignant syringoma 10.1 KRT20 KRT7
9 glandular cystitis 10.1 KRT20 KRT7
10 papillary transitional carcinoma 10.1 KRT20 KRT7
11 eyelid carcinoma 10.1 KRT20 KRT7
12 large intestine adenocarcinoma 10.1 KRT20 KRT7
13 linitis plastica 10.1 KRT20 KRT7
14 lung acinar adenocarcinoma 10.1 KRT20 KRT7
15 small cell carcinoma of the bladder 10.1 KRT20 KRT7
16 small cell carcinoma 10.1 KRT20 KRT7
17 adenoid squamous cell carcinoma 10.1 KRT20 KRT7
18 intratubular embryonal carcinoma 10.1 KRT20 KRT7
19 vulval paget's disease 10.1 KRT20 KRT7
20 bile duct cystadenocarcinoma 10.1 KRT20 KRT7
21 bile duct adenoma 10.1 KRT20 KRT7
22 jejunal adenocarcinoma 10.1 KRT20 KRT7
23 ovarian mucinous adenocarcinoma 10.1 KRT20 KRT7
24 thymus adenocarcinoma 10.1 KRT20 KRT7
25 appendix disease 10.1 KRT20 KRT7
26 gastric diffuse adenocarcinoma 10.1 KRT20 KRT7
27 meibomian cyst 10.1 KRT20 KRT7
28 bladder lymphoma 10.1 KRT20 KRT7
29 papillary serous adenocarcinoma 10.1 KRT20 KRT7
30 bladder adenocarcinoma 10.1 KRT20 KRT7
31 chronic cystitis 10.1 KRT20 KRT7
32 vulva adenocarcinoma 10.1 KRT20 KRT7
33 medulloepithelioma 10.1 KRT20 KRT7
34 glycogen-rich clear cell breast carcinoma 10.1 KRT20 KRT7
35 rectum adenocarcinoma 10.1 KRT20 KRT7
36 renal pelvis carcinoma 10.1 KRT20 KRT7
37 paget disease, extramammary 10.1 KRT20 KRT7
38 mucinous bronchioloalveolar adenocarcinoma 10.1 KRT20 KRT7
39 ampulla of vater adenocarcinoma 10.1 KRT20 KRT7
40 biliary papillomatosis 10.1 KRT20 KRT7
41 papilloma 10.1 KRT20 KRT7
42 lymphoepithelioma-like carcinoma 10.1 KRT20 KRT7
43 endocervical adenocarcinoma 10.1 KRT20 KRT7
44 cervical adenocarcinoma 10.1 KRT20 KRT7
45 eccrine sweat gland neoplasm 10.1 KRT20 KRT7
46 dermoid cyst 10.1 KRT20 KRT7
47 infiltrative basal cell carcinoma 10.1 KRT20 KRT7
48 cystadenofibroma 10.1 KRT20 KRT7
49 ovarian mucinous neoplasm 10.1 KRT20 KRT7
50 thymus lipoma 10.1 KRT20 KRT7

Comorbidity relations with Transverse Colon Cancer via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Ascending Colon Cancer
Cecal Benign Neoplasm Colorectal Cancer
Deficiency Anemia Intestinal Obstruction
Iron Deficiency Anemia Paralytic Ileus
Protein-Energy Malnutrition Rectosigmoid Junction Neoplasm

Graphical network of the top 20 diseases related to Transverse Colon Cancer:



Diseases related to Transverse Colon Cancer

Symptoms & Phenotypes for Transverse Colon Cancer

Drugs & Therapeutics for Transverse Colon Cancer

Drugs for Transverse Colon Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fluorouracil Approved Phase 3 51-21-8 3385
2 Cola Phase 3,Phase 2,Not Applicable
3 Antimetabolites, Antineoplastic Phase 3
4 Antimetabolites Phase 3
5 Immunosuppressive Agents Phase 3
6 Immunologic Factors Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Intra-operative Chemotherapy With 5-FU for Colorectal Cancer Patients Receiving Curative Resection: Efficacy and Safety Active, not recruiting NCT01465451 Phase 3 intra-operative 5-FU chemotherapy
2 Randomized Controlled Trial Between Laparoscopic and Open Surgery in Transverse and Descending Colon Cancer Patients Unknown status NCT01861691 Phase 2
3 Comparison of D2 vs D3 Lymph Node Dissection for Right Colon Cancer (RICON) Recruiting NCT03200834 Not Applicable

Search NIH Clinical Center for Transverse Colon Cancer

Genetic Tests for Transverse Colon Cancer

Anatomical Context for Transverse Colon Cancer

MalaCards organs/tissues related to Transverse Colon Cancer:

42
Colon, Appendix, Lymph Node, Kidney, Thymus, Pancreas, Bone Marrow

Publications for Transverse Colon Cancer

Articles related to Transverse Colon Cancer:

(show top 50) (show all 65)
# Title Authors Year
1
Four-directional approach to the meso-transverse attachment combined with preoperative radiological vascular simulation facilitates short-term surgical outcomes in laparoscopic transverse colon cancer surgery. ( 29963764 )
2019
2
Surgical techniques for advanced transverse colon cancer using the pincer approach of the transverse mesocolon. ( 30353241 )
2019
3
Short- and long-term outcomes after transverse versus extended colectomy for transverse colon cancer. A systematic review and meta-analysis. ( 30402767 )
2019
4
Spontaneous regression of transverse colon cancer with high-frequency microsatellite instability: a case report and literature review. ( 30646898 )
2019
5
Benefit from anti-EGFRs in RAS and BRAF wild-type metastatic transverse colon cancer: a clinical and molecular proof of concept study. ( 30962964 )
2019
6
Reduced-Port Laparoscopic Surgery for Patients With Proximal Transverse Colon Cancer With Situs Inversus Totalis: A Case Report. ( 30630305 )
2018
7
A Transverse Colectomy is as Safe as an Extended Right or Left Colectomy for Mid-Transverse Colon Cancer. ( 29556881 )
2018
8
Optimal Surgery for Mid-Transverse Colon Cancer: Laparoscopic Extended Right Hemicolectomy Versus Laparoscopic Transverse Colectomy. ( 29610931 )
2018
9
Localised perforation of locally advanced transverse colon cancer with spontaneous colocutaneous fistula formation: a clinical challenge. ( 29674405 )
2018
10
Is Robotic Complete Mesocolic Excision Feasible for Transverse Colon Cancer? ( 29878855 )
2018
11
Metachronous rectal metastasis from primary transverse colon cancer: a case report. ( 30094696 )
2018
12
Vascular anatomy of the transverse mesocolon and bidirectional laparoscopic D3 lymph node dissection for patients with advanced transverse colon cancer. ( 30334162 )
2018
13
Short- and long-term outcomes of laparoscopic complete mesocolic excision for transverse colon cancer. ( 30358198 )
2018
14
Laparoscopic complete mesocolic excision via combined medial and cranial approaches for transverse colon cancer. ( 27566603 )
2017
15
Perioperative and short-term oncological outcomes of single-port surgery for transverse colon cancer. ( 27699489 )
2017
16
Comparison of short-term outcomes between laparoscopic-assisted and open complete mesocolic excision (CME) for the treatment of transverse colon cancer. ( 28285536 )
2017
17
Laparoscopic vs open approach for transverse colon cancer. A systematic review and meta-analysis of short and long term outcomes. ( 28344158 )
2017
18
Laparoscopic Colectomy Versus Open Colectomy for Treatment of Transverse Colon Cancer: A Systematic Review and Meta-Analysis. ( 28355104 )
2017
19
Spontaneous regression of transverse colon cancer: a case report. ( 28488173 )
2017
20
Metastases of transverse colon cancer to bilateral ovaries (Krukenberg tumor) and the left breast: A case report. ( 28693131 )
2017
21
A comparison of laparoscopic and open D3 lymphadenectomy for transverse colon cancer. ( 28879395 )
2017
22
Whether partial colectomy is oncologically safe for patients with transverse colon cancer: a large population-based study. ( 29190993 )
2017
23
Perforated Transverse Colon Cancer Presenting as an Incarcerated Inguinal Hernia. ( 28206924 )
2016
24
Pseudo-Meigs' syndrome secondary to metachronous ovarian metastases from transverse colon cancer. ( 27182170 )
2016
25
Laparoscopic Complete Mesocolic Excision versus Open Complete Mesocolic Excision for Transverse Colon Cancer: Long-Term Survival Results of a Prospective Single Centre Non-Randomized Study. ( 26734758 )
2016
26
Laparoscopic resection of transverse colon cancer at splenic flexure: technical aspects and results. ( 27015933 )
2016
27
Delayed cecal perforation after successful colonic metal stenting in a patient with transverse colon cancer. ( 27059038 )
2016
28
Short- and long-term outcomes of laparoscopic surgery vs open surgery for transverse colon cancer: a retrospective multicenter study. ( 27143915 )
2016
29
Perforated Transverse Colon Cancer Presenting as an Incarcerated Inguinal Hernia. ( 28877795 )
2016
30
Ten-millimeter advanced transverse colon cancer accompanied by a sessile serrated adenoma and/or polyp. ( 25892059 )
2015
31
Bullous pemphigoid with IgG autoantibodies to BP180 C-terminal domain and desmocollin 3 associated with transverse colon cancer. ( 26693637 )
2015
32
Metastatic mucinous adenocarcinoma of the distal common bile duct, from transverse colon cancer presenting as obstructive jaundice. ( 26379735 )
2015
33
Laparoscopic versus open resection for transverse colon cancer. ( 25303924 )
2015
34
Preoperative assessment of vascular anatomy by multidetector computed tomography before laparoscopic colectomy for transverse colon cancer: report of a case. ( 25692419 )
2015
35
Transverse colon cancer occurring at a colostomy site 35 years after colostomy: a case report. ( 25943390 )
2015
36
Comparison of long-term follow up of laparoscopic versus open colectomy for transverse colon cancer. ( 26130871 )
2015
37
Outcome of Laparoscopic Versus Open Resection for Transverse Colon Cancer. ( 26197767 )
2015
38
Hematochezia due to Caecal Angiodysplazia led to Diagnosis of a Transverse Colon Cancer in a Young Female Patient: Case Report and Literature Review. ( 26305206 )
2015
39
Initial experience of robotic versus laparoscopic colectomy for transverse colon cancer: a matched case-control study. ( 26452727 )
2015
40
Robotic transverse colectomy for mid-transverse colon cancer: surgical techniques and oncologic outcomes. ( 26531113 )
2015
41
Laparoscopic Surgery for Transverse Colon Cancer: Short- and Long-Term Outcomes in Comparison with Conventional Open Surgery. ( 26583447 )
2015
42
Laparoscopic colectomy for transverse colon cancer: comparative analysis of short- and long-term outcomes. ( 26629108 )
2015
43
Short- and long-term results of laparoscopic surgery for transverse colon cancer. ( 23934542 )
2014
44
Long-term outcomes of laparoscopic surgery for advanced transverse colon cancer. ( 24449001 )
2014
45
Gastrocolic fistula secondary to transverse colon cancer. ( 24717990 )
2014
46
Comparative study of oncologic outcomes for laparoscopic vs. open surgery in transverse colon cancer. ( 24761404 )
2014
47
Transverse colon cancer presenting as acute abdominal wall abscess. ( 24798363 )
2014
48
A Report of Disseminated Carcinomatosis of the Bone Marrow Originating from Transverse Colon Cancer Successfully Treated with Chemotherapy Using XELOX plus Bevacizumab. ( 25126072 )
2014
49
A long adult intussusception secondary to transverse colon cancer. ( 23801849 )
2013
50
Laparoscopic colectomy for transverse colon cancer in an automated peritoneal dialysis patient: A case report. ( 23706995 )
2013

Variations for Transverse Colon Cancer

Expression for Transverse Colon Cancer

Search GEO for disease gene expression data for Transverse Colon Cancer.

Pathways for Transverse Colon Cancer

Pathways related to Transverse Colon Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.47 DSC2 DSC3 KRT20 KRT7
2
Show member pathways
11.38 DSC2 DSC3 KRT20 KRT7

GO Terms for Transverse Colon Cancer

Cellular components related to Transverse Colon Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornified envelope GO:0001533 8.96 DSC2 DSC3
2 desmosome GO:0030057 8.62 DSC2 DSC3

Biological processes related to Transverse Colon Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.26 DSC2 DSC3 KRT20 KRT7
2 cellular response to starvation GO:0009267 9.16 DSC2 KRT20
3 cornification GO:0070268 8.92 DSC2 DSC3 KRT20 KRT7

Sources for Transverse Colon Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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