MCID: TRN003
MIFTS: 35

Transverse Colon Cancer

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Transverse Colon Cancer

MalaCards integrated aliases for Transverse Colon Cancer:

Name: Transverse Colon Cancer 12 15
Malignant Neoplasm of Transverse Colon 73
Malignant Tumor of Transverse Colon 12
Ca Transverse Colon 12

Classifications:



External Ids:

Disease Ontology 12 DOID:261
ICD10 33 C18.4
ICD9CM 35 153.1
UMLS 73 C0153434

Summaries for Transverse Colon Cancer

MalaCards based summary : Transverse Colon Cancer, also known as malignant neoplasm of transverse colon, is related to krukenberg carcinoma and mucinous adenocarcinoma. An important gene associated with Transverse Colon Cancer is ETFA (Electron Transfer Flavoprotein Subunit Alpha), and among its related pathways/superpathways are Developmental Biology and Keratinization. The drugs Fluorouracil and Antimetabolites have been mentioned in the context of this disorder. Affiliated tissues include colon, lymph node and ovary.

Related Diseases for Transverse Colon Cancer

Diseases related to Transverse Colon Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 106)
# Related Disease Score Top Affiliating Genes
1 krukenberg carcinoma 29.5 KRT20 KRT7
2 mucinous adenocarcinoma 29.3 KRT20 KRT7
3 renal-hepatic-pancreatic dysplasia 10.2 ETFA KRT7
4 syndromic x-linked intellectual disability cabezas type 10.2 DSC2 DSC3
5 subcorneal pustular dermatosis 10.0 DSC2 DSC3
6 paraneoplastic pemphigus 10.0 DSC2 DSC3
7 cystic basal cell carcinoma 10.0 KRT20 KRT7
8 vaginal benign neoplasm 10.0 KRT20 KRT7
9 seminal vesicle adenocarcinoma 10.0 KRT20 KRT7
10 appendix adenocarcinoma 10.0 KRT20 KRT7
11 ovarian large-cell neuroendocrine carcinoma 10.0 KRT20 KRT7
12 vaginal adenoma 10.0 KRT20 KRT7
13 vaginal tubulovillous adenoma 9.9 KRT20 KRT7
14 eyelid neoplasm 9.9 KRT20 KRT7
15 glandular cystitis 9.9 KRT20 KRT7
16 malignant syringoma 9.9 KRT20 KRT7
17 large intestine adenocarcinoma 9.9 KRT20 KRT7
18 linitis plastica 9.9 KRT20 KRT7
19 large cell carcinoma 9.9 DSC3 KRT7
20 lung acinar adenocarcinoma 9.9 KRT20 KRT7
21 small cell carcinoma of the bladder 9.9 KRT20 KRT7
22 adenoid squamous cell carcinoma 9.9 KRT20 KRT7
23 eccrine sweat gland neoplasm 9.9 KRT20 KRT7
24 mucinous bronchioloalveolar adenocarcinoma 9.9 KRT20 KRT7
25 vulval paget's disease 9.9 KRT20 KRT7
26 bile duct cystadenocarcinoma 9.9 KRT20 KRT7
27 intratubular embryonal carcinoma 9.9 KRT20 KRT7
28 ovarian mucinous adenocarcinoma 9.9 KRT20 KRT7
29 thymus adenocarcinoma 9.9 KRT20 KRT7
30 gastric diffuse adenocarcinoma 9.9 KRT20 KRT7
31 meibomian cyst 9.9 KRT20 KRT7
32 bladder lymphoma 9.9 KRT20 KRT7
33 papillary serous adenocarcinoma 9.9 KRT20 KRT7
34 bladder adenocarcinoma 9.9 KRT20 KRT7
35 jejunal adenocarcinoma 9.9 KRT20 KRT7
36 chronic cystitis 9.9 KRT20 KRT7
37 vulva adenocarcinoma 9.9 KRT20 KRT7
38 medulloepithelioma 9.9 KRT20 KRT7
39 glycogen-rich clear cell breast carcinoma 9.9 KRT20 KRT7
40 rectum adenocarcinoma 9.9 KRT20 KRT7
41 renal pelvis carcinoma 9.9 KRT20 KRT7
42 paget disease, extramammary 9.9 KRT20 KRT7
43 ampulla of vater neoplasm 9.9 KRT20 KRT7
44 appendix cancer 9.9 KRT20 KRT7
45 ampulla of vater adenocarcinoma 9.9 KRT20 KRT7
46 mucinous cystadenocarcinoma 9.9 KRT20 KRT7
47 inguinal hernia 9.9
48 adenocarcinoma 9.9
49 biliary papillomatosis 9.9 KRT20 KRT7
50 lymphoepithelioma-like carcinoma 9.9 KRT20 KRT7

Comorbidity relations with Transverse Colon Cancer via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Ascending Colon Cancer
Cecal Benign Neoplasm Colorectal Cancer
Deficiency Anemia Intestinal Obstruction
Iron Deficiency Anemia Paralytic Ileus
Protein-Energy Malnutrition Rectosigmoid Junction Neoplasm

Graphical network of the top 20 diseases related to Transverse Colon Cancer:



Diseases related to Transverse Colon Cancer

Symptoms & Phenotypes for Transverse Colon Cancer

Drugs & Therapeutics for Transverse Colon Cancer

Drugs for Transverse Colon Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fluorouracil Approved Phase 3 51-21-8 3385
2 Antimetabolites Phase 3
3 Antimetabolites, Antineoplastic Phase 3
4 Immunosuppressive Agents Phase 3
5 Cola Nutraceutical Phase 3,Phase 2,Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Intra-operative Chemotherapy With 5-FU for Colorectal Cancer Patients Receiving Curative Resection: Efficacy and Safety Active, not recruiting NCT01465451 Phase 3 intra-operative 5-FU chemotherapy
2 Randomized Controlled Trial Between Laparoscopic and Open Surgery in Transverse and Descending Colon Cancer Patients Unknown status NCT01861691 Phase 2
3 Comparison of D2 vs D3 Lymph Node Dissection for Right Colon Cancer (RICON) Recruiting NCT03200834 Not Applicable

Search NIH Clinical Center for Transverse Colon Cancer

Genetic Tests for Transverse Colon Cancer

Anatomical Context for Transverse Colon Cancer

MalaCards organs/tissues related to Transverse Colon Cancer:

41
Colon, Lymph Node, Ovary, Pancreas, Bone Marrow, Bone, Liver

Publications for Transverse Colon Cancer

Articles related to Transverse Colon Cancer:

(show top 50) (show all 56)
# Title Authors Year
1
Optimal Surgery for Mid-Transverse Colon Cancer: Laparoscopic Extended Right Hemicolectomy Versus Laparoscopic Transverse Colectomy. ( 29610931 )
2018
2
Localised perforation of locally advanced transverse colon cancer with spontaneous colocutaneous fistula formation: a clinical challenge. ( 29674405 )
2018
3
Is Robotic Complete Mesocolic Excision Feasible for Transverse Colon Cancer? ( 29878855 )
2018
4
A Transverse Colectomy is as Safe as an Extended Right or Left Colectomy for Mid-Transverse Colon Cancer. ( 29556881 )
2018
5
Four-directional approach to the meso-transverse attachment combined with preoperative radiological vascular simulation facilitates short-term surgical outcomes in laparoscopic transverse colon cancer surgery. ( 29963764 )
2018
6
Metastases of transverse colon cancer to bilateral ovaries (Krukenberg tumor) and the left breast: A case report. ( 28693131 )
2017
7
Whether partial colectomy is oncologically safe for patients with transverse colon cancer: a large population-based study. ( 29190993 )
2017
8
Spontaneous regression of transverse colon cancer: a case report. ( 28488173 )
2017
9
A comparison of laparoscopic and open D3 lymphadenectomy for transverse colon cancer. ( 28879395 )
2017
10
Laparoscopic vs open approach for transverse colon cancer. A systematic review and meta-analysis of short and long term outcomes. ( 28344158 )
2017
11
Laparoscopic Colectomy Versus Open Colectomy for Treatment of Transverse Colon Cancer: A Systematic Review and Meta-Analysis. ( 28355104 )
2017
12
Comparison of short-term outcomes between laparoscopic-assisted and open complete mesocolic excision (CME) for the treatment of transverse colon cancer. ( 28285536 )
2017
13
Perioperative and short-term oncological outcomes of single-port surgery for transverse colon cancer. ( 27699489 )
2016
14
Laparoscopic resection of transverse colon cancer at splenic flexure: technical aspects and results. ( 27015933 )
2016
15
Laparoscopic complete mesocolic excision via combined medial and cranial approaches for transverse colon cancer. ( 27566603 )
2016
16
Delayed cecal perforation after successful colonic metal stenting in a patient with transverse colon cancer. ( 27059038 )
2016
17
Short- and long-term outcomes of laparoscopic surgery vs open surgery for transverse colon cancer: a retrospective multicenter study. ( 27143915 )
2016
18
Perforated Transverse Colon Cancer Presenting as an Incarcerated Inguinal Hernia. ( 28206924 )
2016
19
Perforated Transverse Colon Cancer Presenting as an Incarcerated Inguinal Hernia. ( 28877795 )
2016
20
Laparoscopic Complete Mesocolic Excision versus Open Complete Mesocolic Excision for Transverse Colon Cancer: Long-Term Survival Results of a Prospective Single Centre Non-Randomized Study. ( 26734758 )
2016
21
Pseudo-Meigs' syndrome secondary to metachronous ovarian metastases from transverse colon cancer. ( 27182170 )
2016
22
Metastatic mucinous adenocarcinoma of the distal common bile duct, from transverse colon cancer presenting as obstructive jaundice. ( 26379735 )
2015
23
Laparoscopic colectomy for transverse colon cancer: comparative analysis of short- and long-term outcomes. ( 26629108 )
2015
24
Preoperative assessment of vascular anatomy by multidetector computed tomography before laparoscopic colectomy for transverse colon cancer: report of a case. ( 25692419 )
2015
25
Ten-millimeter advanced transverse colon cancer accompanied by a sessile serrated adenoma and/or polyp. ( 25892059 )
2015
26
Initial experience of robotic versus laparoscopic colectomy for transverse colon cancer: a matched case-control study. ( 26452727 )
2015
27
Laparoscopic Surgery for Transverse Colon Cancer: Short- and Long-Term Outcomes in Comparison with Conventional Open Surgery. ( 26583447 )
2015
28
Hematochezia due to Caecal Angiodysplazia led to Diagnosis of a Transverse Colon Cancer in a Young Female Patient: Case Report and Literature Review. ( 26305206 )
2015
29
Comparison of long-term follow up of laparoscopic versus open colectomy for transverse colon cancer. ( 26130871 )
2015
30
Robotic transverse colectomy for mid-transverse colon cancer: surgical techniques and oncologic outcomes. ( 26531113 )
2015
31
Bullous pemphigoid with IgG autoantibodies to BP180 C-terminal domain and desmocollin 3 associated with transverse colon cancer. ( 26693637 )
2015
32
Transverse colon cancer occurring at a colostomy site 35 years after colostomy: a case report. ( 25943390 )
2015
33
Outcome of Laparoscopic Versus Open Resection for Transverse Colon Cancer. ( 26197767 )
2015
34
Comparative study of oncologic outcomes for laparoscopic vs. open surgery in transverse colon cancer. ( 24761404 )
2014
35
A Report of Disseminated Carcinomatosis of the Bone Marrow Originating from Transverse Colon Cancer Successfully Treated with Chemotherapy Using XELOX plus Bevacizumab. ( 25126072 )
2014
36
Transverse colon cancer presenting as acute abdominal wall abscess. ( 24798363 )
2014
37
Laparoscopic versus open resection for transverse colon cancer. ( 25303924 )
2014
38
Long-term outcomes of laparoscopic surgery for advanced transverse colon cancer. ( 24449001 )
2014
39
Gastrocolic fistula secondary to transverse colon cancer. ( 24717990 )
2014
40
A long adult intussusception secondary to transverse colon cancer. ( 23801849 )
2013
41
Laparoscopic colectomy for transverse colon cancer in an automated peritoneal dialysis patient: A case report. ( 23706995 )
2013
42
The transverse colon cancer with the reversed rotation of the midgut treated with single incision laparoscopic colectomy. ( 24426562 )
2013
43
Invasive adenocarcinoma arising from a mixed hyperplastic/adenomatous polyp and synchronous transverse colon cancer. ( 23984814 )
2013
44
Short- and long-term results of laparoscopic surgery for transverse colon cancer. ( 23934542 )
2013
45
A new approach to laparoscopic lymph node excision in cases of transverse colon cancer. ( 22269292 )
2012
46
Laparoscopic resection of transverse colon cancer: long-term oncologic outcomes in 58 patients. ( 22690652 )
2012
47
Curative resection of transverse colon cancer via minilaparotomy. ( 21675613 )
2011
48
Surgical resection of locally advanced primary transverse colon cancer--not a worse outcome in stage II tumor. ( 21279365 )
2011
49
Short-term outcomes of laparoscopic colectomy for transverse colon cancer. ( 20224982 )
2010
50
Left paraduodenal hernia incidentally diagnosed during operation for transverse colon cancer. ( 20453424 )
2010

Variations for Transverse Colon Cancer

Expression for Transverse Colon Cancer

Search GEO for disease gene expression data for Transverse Colon Cancer.

Pathways for Transverse Colon Cancer

Pathways related to Transverse Colon Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.47 DSC2 DSC3 KRT20 KRT7
2
Show member pathways
11.38 DSC2 DSC3 KRT20 KRT7

GO Terms for Transverse Colon Cancer

Cellular components related to Transverse Colon Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornified envelope GO:0001533 8.96 DSC2 DSC3
2 desmosome GO:0030057 8.62 DSC2 DSC3

Biological processes related to Transverse Colon Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 9.26 DSC2 DSC3
2 keratinization GO:0031424 9.26 DSC2 DSC3 KRT20 KRT7
3 cellular response to starvation GO:0009267 9.16 DSC2 KRT20
4 cornification GO:0070268 8.92 DSC2 DSC3 KRT20 KRT7

Sources for Transverse Colon Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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