MCID: TRM002
MIFTS: 25

Traumatic Glaucoma

Categories: Eye diseases

Aliases & Classifications for Traumatic Glaucoma

MalaCards integrated aliases for Traumatic Glaucoma:

Name: Traumatic Glaucoma 12 15
Glaucoma Associated with Ocular Trauma 12 71

Classifications:



External Ids:

Disease Ontology 12 DOID:13060
ICD9CM 34 365.65
SNOMED-CT 67 68241007
UMLS 71 C0339594

Summaries for Traumatic Glaucoma

MalaCards based summary : Traumatic Glaucoma, also known as glaucoma associated with ocular trauma, is related to corneal edema and open-angle glaucoma. An important gene associated with Traumatic Glaucoma is SERPINA9 (Serpin Family A Member 9), and among its related pathways/superpathways is Benzodiazepine Pathway, Pharmacodynamics. The drugs Triamcinolone and Pharmaceutical Solutions have been mentioned in the context of this disorder. Affiliated tissues include eye, and related phenotype is no phenotypic analysis.

Related Diseases for Traumatic Glaucoma

Graphical network of the top 20 diseases related to Traumatic Glaucoma:



Diseases related to Traumatic Glaucoma

Symptoms & Phenotypes for Traumatic Glaucoma

MGI Mouse Phenotypes related to Traumatic Glaucoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 no phenotypic analysis MP:0003012 8.92 AFAP1 LTBP2 MYOC SLC6A13

Drugs & Therapeutics for Traumatic Glaucoma

Drugs for Traumatic Glaucoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Triamcinolone Approved, Vet_approved Phase 2, Phase 3 124-94-7 31307
2 Pharmaceutical Solutions Phase 2, Phase 3
3 Immunologic Factors Phase 2, Phase 3
4 Hormone Antagonists Phase 2, Phase 3
5 triamcinolone acetonide Phase 2, Phase 3
6 Anti-Inflammatory Agents Phase 2, Phase 3
7 Triamcinolone diacetate Phase 2, Phase 3
8 glucocorticoids Phase 2, Phase 3
9 Immunosuppressive Agents Phase 2, Phase 3
10 Hormones Phase 2, Phase 3
11 Triamcinolone hexacetonide Phase 2, Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Effect of Intracameral Triesence (Triamcinolone Acetonide Injectable Suspension) on Ocular Inflammation After Trabeculectomy, Tube Shunt Implantation or Combined Trabeculectomy With Cataract Surgery Completed NCT00853905 Phase 2, Phase 3 Triesence;balanced salt solution BSS

Search NIH Clinical Center for Traumatic Glaucoma

Genetic Tests for Traumatic Glaucoma

Anatomical Context for Traumatic Glaucoma

MalaCards organs/tissues related to Traumatic Glaucoma:

40
Eye

Publications for Traumatic Glaucoma

Articles related to Traumatic Glaucoma:

(show top 50) (show all 102)
# Title Authors PMID Year
1
Work tool-related eye injuries: Helsinki Ocular Trauma Study. 61
31811447 2019
2
Incidence, clinical profile, and short-term outcomes of post-traumatic glaucoma in pediatric eyes. 61
30900584 2019
3
Profile of childhood glaucoma at a tertiary center in South India. 61
30777953 2019
4
Chronic Intraocular Inflammation as a Risk Factor for XEN Gel Stent Occlusion: A Case of Microscopic Examination of a Fibrin-obstructed XEN Stent. 61
29877971 2018
5
Optical Coherence Tomography Angiography Description of Ocular Decompression Retinopathy After Deep Sclerectomy in Traumatic Glaucoma. 61
29303876 2018
6
Traumatic glaucoma due to paintball injuries: A case series. 61
29270481 2017
7
Knocked by the shuttlecock: twelve sight-threatening blunt-eye injuries in Australian badminton players. 61
27998001 2017
8
Combined vitrectomy and glaucoma drainage device implantation surgical approach for complex pediatric glaucomas. 61
28254440 2017
9
Surgical Outcomes of Ahmed or Baerveldt Tube Shunt Implantation for medically Uncontrolled Traumatic Glaucoma. 61
28138213 2017
10
Artificial iris implantation in a male with post-traumatic aniridia - case report. 61
29715406 2016
11
Abnormal increase of intraocular pressure in fellow eye after severe ocular trauma: A case report. 61
27495058 2016
12
Glaucoma After Open-globe Injury at a Tertiary Care University Hospital: Cumulative Causes and Management. 61
25265009 2016
13
Transpupillary Argon Laser Cyclophotocoagulation in a Refractory Traumatic Glaucoma Patient with Aphakia and Aniridia. 61
27800256 2016
14
Trabecular micro-bypass stent implantation during small-incision cataract surgery for open-angle glaucoma or ocular hypertension: Long-term results. 61
26796447 2015
15
Incidence and risk factors for traumatic intraocular pressure elevation and traumatic glaucoma after open-globe injury. 61
26381097 2015
16
Glaucoma after open globe injury. 61
26155083 2015
17
Vitreous occlusion of tube implant in a phakic patient with traumatic glaucoma. 61
25378882 2014
18
Traumatic Glaucoma in Children. 61
26997810 2014
19
[Post-traumatic lens dislocation presenting as an eclipse in a patient demonstrating monocular blindness secondary to post-traumatic glaucoma]. 61
24680036 2014
20
Profile of pediatric glaucoma patients in Shanghai Eye, Ear, Nose and Throat Hospital. 61
24762583 2014
21
Traumatic glaucoma with features of unilateral pigment dispersion. 61
25097455 2014
22
[A case of ring melanoma found while treating traumatic glaucoma]. 61
23767193 2013
23
Glaucoma after open globe injury at a tertiary care university hospital in Central Saudi Arabia. Cumulative incidence and risk factors. 61
23552590 2013
24
Central serous retinal detachment following glaucoma filtration surgery. 61
22705275 2012
25
[Non-penetrating glaucoma surgery]. 61
22911357 2012
26
Comparison of optical coherence tomography findings in a patient with central retinal artery occlusion in one eye and end-stage glaucoma in the fellow eye. 61
22623869 2012
27
Factors related to prognosis of refractory glaucoma with diode laser transscleral cyclophotocoagulation treatment. 61
22207920 2011
28
Blunt eye trauma: empirical histopathologic paintball impact thresholds in fresh mounted porcine eyes. 61
21508104 2011
29
An unusual case of glaucoma: traumatic glaucoma probably caused by shock waves. 61
20220403 2010
30
[The evaluation of efficacy of Ahmed valve implantation in the surgical treatment of glaucoma in children and adolescents]. 61
20825062 2010
31
Epidemiology of hospitalized pediatric glaucoma patients in Beijing Tongren Hospital. 61
19493464 2009
32
Causes and treatments of traumatic secondary glaucoma. 61
19253235 2009
33
Early predictors of traumatic glaucoma after closed globe injury: trabecular pigmentation, widened angle recess, and higher baseline intraocular pressure. 61
18625937 2008
34
Current profile of secondary glaucomas. 61
18579986 2008
35
Long-term outcome of trans-scleral diode laser cyclophotocoagulation in refractory glaucoma. 61
17494956 2007
36
[Prevalence of glaucomas in a Black Cameroonian population]. 61
17116629 2006
37
[Traumatic glaucoma--a survey]. 61
16240269 2005
38
[Molteno/von Denffer drainage implants in therapy-refractory glaucomas]. 61
16240278 2005
39
[Dramatic alteration in optic nerve head topography after filtering surgery in an adult patient with traumatic glaucoma]. 61
16218440 2005
40
Ocular injury in hurling. 61
16046328 2005
41
[Clinical analysis of early secondary glaucoma associated with ocular trauma]. 61
15938810 2005
42
[Ahmed drainage device implant. Our experience between 1995 and 2003]. 61
15852165 2005
43
Ocular blood flow evaluation in injured and healthy fellow eyes. 61
15751239 2005
44
Glaucoma following penetrating ocular trauma: a cohort study of the United States Eye Injury Registry. 61
15652833 2005
45
[Post-traumatic glaucoma with irido-corneal angle injuries in Cameroon]. 61
16422218 2005
46
[Surgical management of secondary angle closure glaucoma after trauma]. 61
15343448 2004
47
Bottle-cork injury to the eye: a review of 13 cases. 61
12747650 2003
48
Endoscopic cyclophotocoagulation. 61
12446381 2002
49
[Long-term experience with glaucoma silicone implants in a multicenter study]. 61
12181878 2002
50
Progressive axial myopia in a juvenile patient with traumatic glaucoma. 61
11992870 2002

Variations for Traumatic Glaucoma

Expression for Traumatic Glaucoma

Search GEO for disease gene expression data for Traumatic Glaucoma.

Pathways for Traumatic Glaucoma

Pathways related to Traumatic Glaucoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
9.88 SLC6A13 SLC6A12

GO Terms for Traumatic Glaucoma

Cellular components related to Traumatic Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.02 SLC6A13 NUDT5 MYOC LTBP2 GMDS

Biological processes related to Traumatic Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neurotransmitter transport GO:0006836 8.96 SLC6A13 SLC6A12
2 gamma-aminobutyric acid transport GO:0015812 8.62 SLC6A13 SLC6A12

Molecular functions related to Traumatic Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 symporter activity GO:0015293 9.16 SLC6A13 SLC6A12
2 neurotransmitter binding GO:0042165 8.96 SLC6A13 SLC6A12
3 gamma-aminobutyric acid:sodium symporter activity GO:0005332 8.62 SLC6A13 SLC6A12

Sources for Traumatic Glaucoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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