MCID: TRM002
MIFTS: 24

Traumatic Glaucoma

Categories: Eye diseases

Aliases & Classifications for Traumatic Glaucoma

MalaCards integrated aliases for Traumatic Glaucoma:

Name: Traumatic Glaucoma 12 15
Glaucoma Associated with Ocular Trauma 12 72

Classifications:



External Ids:

Disease Ontology 12 DOID:13060
ICD9CM 35 365.65
SNOMED-CT 68 68241007
UMLS 72 C0339594

Summaries for Traumatic Glaucoma

MalaCards based summary : Traumatic Glaucoma, also known as glaucoma associated with ocular trauma, is related to glaucoma 1, open angle, a and intraocular pressure quantitative trait locus. An important gene associated with Traumatic Glaucoma is SLC6A12 (Solute Carrier Family 6 Member 12), and among its related pathways/superpathways are Transmission across Chemical Synapses and Neurotransmitter Release Cycle. The drugs Triamcinolone and Triamcinolone hexacetonide have been mentioned in the context of this disorder. Affiliated tissues include eye.

Related Diseases for Traumatic Glaucoma

Diseases related to Traumatic Glaucoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 17)
# Related Disease Score Top Affiliating Genes
1 glaucoma 1, open angle, a 11.3
2 intraocular pressure quantitative trait locus 10.6
3 yemenite deaf-blind hypopigmentation syndrome 10.0
4 retinal detachment 10.0
5 open-angle glaucoma 9.9
6 cataract 9.9
7 aniridia 1 9.8
8 glaucoma, primary open angle 9.8
9 siderosis 9.8
10 corneal edema 9.8
11 lens subluxation 9.8
12 myopia 9.8
13 sympathetic ophthalmia 9.8
14 neovascular glaucoma 9.8
15 melanoma 9.8
16 ocular hypertension 9.8
17 hypertonia 9.8

Graphical network of the top 20 diseases related to Traumatic Glaucoma:



Diseases related to Traumatic Glaucoma

Symptoms & Phenotypes for Traumatic Glaucoma

Drugs & Therapeutics for Traumatic Glaucoma

Drugs for Traumatic Glaucoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Triamcinolone Approved, Vet_approved Phase 2, Phase 3 124-94-7 31307
2 Triamcinolone hexacetonide Phase 2, Phase 3
3 Immunologic Factors Phase 2, Phase 3
4 triamcinolone acetonide Phase 2, Phase 3
5 Triamcinolone diacetate Phase 2, Phase 3
6 glucocorticoids Phase 2, Phase 3
7 Anti-Inflammatory Agents Phase 2, Phase 3
8 Hormones Phase 2, Phase 3
9 Pharmaceutical Solutions Phase 2, Phase 3
10 Immunosuppressive Agents Phase 2, Phase 3
11 Hormone Antagonists Phase 2, Phase 3
12 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2, Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Effect of Intracameral Triesence (Triamcinolone Acetonide Injectable Suspension) on Ocular Inflammation After Trabeculectomy, Tube Shunt Implantation or Combined Trabeculectomy With Cataract Surgery Completed NCT00853905 Phase 2, Phase 3 Triesence;balanced salt solution BSS

Search NIH Clinical Center for Traumatic Glaucoma

Genetic Tests for Traumatic Glaucoma

Anatomical Context for Traumatic Glaucoma

MalaCards organs/tissues related to Traumatic Glaucoma:

41
Eye

Publications for Traumatic Glaucoma

Articles related to Traumatic Glaucoma:

(show top 50) (show all 101)
# Title Authors PMID Year
1
Incidence, clinical profile, and short-term outcomes of post-traumatic glaucoma in pediatric eyes. 38
30900584 2019
2
Profile of childhood glaucoma at a tertiary center in South India. 38
30777953 2019
3
Chronic Intraocular Inflammation as a Risk Factor for XEN Gel Stent Occlusion: A Case of Microscopic Examination of a Fibrin-obstructed XEN Stent. 38
29877971 2018
4
Optical Coherence Tomography Angiography Description of Ocular Decompression Retinopathy After Deep Sclerectomy in Traumatic Glaucoma. 38
29303876 2018
5
Traumatic glaucoma due to paintball injuries: A case series. 38
29270481 2017
6
Knocked by the shuttlecock: twelve sight-threatening blunt-eye injuries in Australian badminton players. 38
27998001 2017
7
Combined vitrectomy and glaucoma drainage device implantation surgical approach for complex pediatric glaucomas. 38
28254440 2017
8
Surgical Outcomes of Ahmed or Baerveldt Tube Shunt Implantation for medically Uncontrolled Traumatic Glaucoma. 38
28138213 2017
9
Artificial iris implantation in a male with post-traumatic aniridia - case report. 38
29715406 2016
10
Abnormal increase of intraocular pressure in fellow eye after severe ocular trauma: A case report. 38
27495058 2016
11
Glaucoma After Open-globe Injury at a Tertiary Care University Hospital: Cumulative Causes and Management. 38
25265009 2016
12
Transpupillary Argon Laser Cyclophotocoagulation in a Refractory Traumatic Glaucoma Patient with Aphakia and Aniridia. 38
27800256 2016
13
Trabecular micro-bypass stent implantation during small-incision cataract surgery for open-angle glaucoma or ocular hypertension: Long-term results. 38
26796447 2015
14
Incidence and risk factors for traumatic intraocular pressure elevation and traumatic glaucoma after open-globe injury. 38
26381097 2015
15
Glaucoma after open globe injury. 38
26155083 2015
16
Vitreous occlusion of tube implant in a phakic patient with traumatic glaucoma. 38
25378882 2014
17
[Post-traumatic lens dislocation presenting as an eclipse in a patient demonstrating monocular blindness secondary to post-traumatic glaucoma]. 38
24680036 2014
18
Traumatic Glaucoma in Children. 38
26997810 2014
19
Traumatic glaucoma with features of unilateral pigment dispersion. 38
25097455 2014
20
Profile of pediatric glaucoma patients in Shanghai Eye, Ear, Nose and Throat Hospital. 38
24762583 2014
21
[A case of ring melanoma found while treating traumatic glaucoma]. 38
23767193 2013
22
Glaucoma after open globe injury at a tertiary care university hospital in Central Saudi Arabia. Cumulative incidence and risk factors. 38
23552590 2013
23
Central serous retinal detachment following glaucoma filtration surgery. 38
22705275 2012
24
[Non-penetrating glaucoma surgery]. 38
22911357 2012
25
Comparison of optical coherence tomography findings in a patient with central retinal artery occlusion in one eye and end-stage glaucoma in the fellow eye. 38
22623869 2012
26
Factors related to prognosis of refractory glaucoma with diode laser transscleral cyclophotocoagulation treatment. 38
22207920 2011
27
Blunt eye trauma: empirical histopathologic paintball impact thresholds in fresh mounted porcine eyes. 38
21508104 2011
28
An unusual case of glaucoma: traumatic glaucoma probably caused by shock waves. 38
20220403 2010
29
[The evaluation of efficacy of Ahmed valve implantation in the surgical treatment of glaucoma in children and adolescents]. 38
20825062 2010
30
Epidemiology of hospitalized pediatric glaucoma patients in Beijing Tongren Hospital. 38
19493464 2009
31
Causes and treatments of traumatic secondary glaucoma. 38
19253235 2009
32
Current profile of secondary glaucomas. 38
18579986 2008
33
Early predictors of traumatic glaucoma after closed globe injury: trabecular pigmentation, widened angle recess, and higher baseline intraocular pressure. 38
18625937 2008
34
Long-term outcome of trans-scleral diode laser cyclophotocoagulation in refractory glaucoma. 38
17494956 2007
35
[Prevalence of glaucomas in a Black Cameroonian population]. 38
17116629 2006
36
[Traumatic glaucoma--a survey]. 38
16240269 2005
37
[Molteno/von Denffer drainage implants in therapy-refractory glaucomas]. 38
16240278 2005
38
[Dramatic alteration in optic nerve head topography after filtering surgery in an adult patient with traumatic glaucoma]. 38
16218440 2005
39
Ocular injury in hurling. 38
16046328 2005
40
[Clinical analysis of early secondary glaucoma associated with ocular trauma]. 38
15938810 2005
41
[Ahmed drainage device implant. Our experience between 1995 and 2003]. 38
15852165 2005
42
Ocular blood flow evaluation in injured and healthy fellow eyes. 38
15751239 2005
43
Glaucoma following penetrating ocular trauma: a cohort study of the United States Eye Injury Registry. 38
15652833 2005
44
[Post-traumatic glaucoma with irido-corneal angle injuries in Cameroon]. 38
16422218 2005
45
[Surgical management of secondary angle closure glaucoma after trauma]. 38
15343448 2004
46
Bottle-cork injury to the eye: a review of 13 cases. 38
12747650 2003
47
Endoscopic cyclophotocoagulation. 38
12446381 2002
48
[Long-term experience with glaucoma silicone implants in a multicenter study]. 38
12181878 2002
49
Progressive axial myopia in a juvenile patient with traumatic glaucoma. 38
11992870 2002
50
Cumulative effect of risk factors on short-term surgical success of mitomycin augmented trabeculectomy. 38
12215687 2002

Variations for Traumatic Glaucoma

Expression for Traumatic Glaucoma

Search GEO for disease gene expression data for Traumatic Glaucoma.

Pathways for Traumatic Glaucoma

GO Terms for Traumatic Glaucoma

Cellular components related to Traumatic Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuron projection GO:0043005 8.62 SLC6A13 SLC6A12

Biological processes related to Traumatic Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane transport GO:0055085 9.16 SLC6A13 SLC6A12
2 neurotransmitter transport GO:0006836 8.96 SLC6A13 SLC6A12
3 gamma-aminobutyric acid transport GO:0015812 8.62 SLC6A13 SLC6A12

Molecular functions related to Traumatic Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 symporter activity GO:0015293 9.16 SLC6A13 SLC6A12
2 neurotransmitter binding GO:0042165 8.96 SLC6A13 SLC6A12
3 gamma-aminobutyric acid:sodium symporter activity GO:0005332 8.62 SLC6A13 SLC6A12

Sources for Traumatic Glaucoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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