MCID: TRM002
MIFTS: 23

Traumatic Glaucoma

Categories: Eye diseases

Aliases & Classifications for Traumatic Glaucoma

MalaCards integrated aliases for Traumatic Glaucoma:

Name: Traumatic Glaucoma 12 15
Glaucoma Associated with Ocular Trauma 12 74

Classifications:



External Ids:

Disease Ontology 12 DOID:13060
ICD9CM 36 365.65
SNOMED-CT 69 68241007
UMLS 74 C0339594

Summaries for Traumatic Glaucoma

MalaCards based summary : Traumatic Glaucoma, also known as glaucoma associated with ocular trauma, is related to glaucoma 1, open angle, a and myopia. An important gene associated with Traumatic Glaucoma is SLC6A12 (Solute Carrier Family 6 Member 12), and among its related pathways/superpathways are Neurotransmitter Release Cycle and Benzodiazepine Pathway, Pharmacodynamics. The drugs Triamcinolone and Triamcinolone hexacetonide have been mentioned in the context of this disorder. Affiliated tissues include eye.

Related Diseases for Traumatic Glaucoma

Diseases related to Traumatic Glaucoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 glaucoma 1, open angle, a 11.2
2 myopia 9.8
3 glaucoma, primary open angle 9.5 PHEX SLC6A13

Symptoms & Phenotypes for Traumatic Glaucoma

Drugs & Therapeutics for Traumatic Glaucoma

Drugs for Traumatic Glaucoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Triamcinolone Approved, Vet_approved Phase 2, Phase 3 124-94-7 31307
2 Triamcinolone hexacetonide Phase 2, Phase 3
3 Anti-Inflammatory Agents Phase 2, Phase 3
4 Hormones Phase 2, Phase 3
5 Immunosuppressive Agents Phase 2, Phase 3
6 Hormone Antagonists Phase 2, Phase 3
7 Immunologic Factors Phase 2, Phase 3
8 Triamcinolone diacetate Phase 2, Phase 3
9 triamcinolone acetonide Phase 2, Phase 3
10 glucocorticoids Phase 2, Phase 3
11 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2, Phase 3
12 Pharmaceutical Solutions Phase 2, Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Will the Use of Triesence During Glaucoma Surgery Provide Lower Eye Pressure and Improve the Results of the Surgery? Completed NCT00853905 Phase 2, Phase 3 Triesence;balanced salt solution BSS
2 Laminar Drainage Implant: Safety of a Novel Surgical Treatment for Refractory Glaucoma. Completed NCT03166566 Not Applicable
3 Patch Graft Material Safety and Effectiveness in Covering Glaucoma Drainage Device Tube Terminated NCT01301378 Not Applicable

Search NIH Clinical Center for Traumatic Glaucoma

Genetic Tests for Traumatic Glaucoma

Anatomical Context for Traumatic Glaucoma

MalaCards organs/tissues related to Traumatic Glaucoma:

42
Eye

Publications for Traumatic Glaucoma

Articles related to Traumatic Glaucoma:

(show all 23)
# Title Authors Year
1
Incidence, clinical profile, and short-term outcomes of post-traumatic glaucoma in pediatric eyes. ( 30900584 )
2019
2
Optical Coherence Tomography Angiography Description of Ocular Decompression Retinopathy after Deep Sclerectomy in Traumatic Glaucoma. ( 29303876 )
2018
3
Traumatic glaucoma due to paintball injuries: A case series. ( 29270481 )
2017
4
Surgical Outcomes of Ahmed or Baerveldt Tube Shunt Implantation for medically Uncontrolled Traumatic Glaucoma. ( 28138213 )
2017
5
Transpupillary Argon Laser Cyclophotocoagulation in a Refractory Traumatic Glaucoma Patient with Aphakia and Aniridia. ( 27800256 )
2016
6
Incidence and risk factors for traumatic intraocular pressure elevation and traumatic glaucoma after open-globe injury. ( 26381097 )
2015
7
Vitreous occlusion of tube implant in a phakic patient with traumatic glaucoma. ( 25378882 )
2014
8
Traumatic Glaucoma in Children. ( 26997810 )
2014
9
Traumatic glaucoma with features of unilateral pigment dispersion. ( 25097455 )
2014
10
An unusual case of glaucoma: traumatic glaucoma probably caused by shock waves. ( 20220403 )
2010
11
Early predictors of traumatic glaucoma after closed globe injury: trabecular pigmentation, widened angle recess, and higher baseline intraocular pressure. ( 18625937 )
2008
12
Progressive axial myopia in a juvenile patient with traumatic glaucoma. ( 11992870 )
2002
13
Long-term follow-up of traumatic glaucoma treated with Molteno implants. ( 11581051 )
2001
14
Traumatic glaucoma. ( 11816998 )
2001
15
Traumatic glaucoma. ( 11711845 )
2001
16
Transpupillary argon laser cyclophotocoagulation in the treatment of traumatic glaucoma. ( 10529935 )
1999
17
Traumatic glaucoma. ( 7493239 )
1995
18
Trabecular damage due to blunt anterior segment injury and its relationship to traumatic glaucoma. ( 406709 )
1977
19
Traumatic glaucoma--the thief of sight. ( 1152637 )
1975
20
Traumatic glaucoma. ( 4825066 )
1974
21
The management of traumatic glaucoma. ( 5133221 )
1971
22
Traumatic glaucoma. ( 5607317 )
1967
23
Use of radium for traumatic glaucoma. ( 14937033 )
1952

Variations for Traumatic Glaucoma

Expression for Traumatic Glaucoma

Search GEO for disease gene expression data for Traumatic Glaucoma.

Pathways for Traumatic Glaucoma

GO Terms for Traumatic Glaucoma

Cellular components related to Traumatic Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuron projection GO:0043005 8.96 SLC6A12 SLC6A13
2 integral component of plasma membrane GO:0005887 8.8 PHEX SLC6A12 SLC6A13

Biological processes related to Traumatic Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane transport GO:0055085 9.16 SLC6A12 SLC6A13
2 neurotransmitter transport GO:0006836 8.96 SLC6A12 SLC6A13
3 gamma-aminobutyric acid transport GO:0015812 8.62 SLC6A12 SLC6A13

Molecular functions related to Traumatic Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 symporter activity GO:0015293 9.16 SLC6A12 SLC6A13
2 neurotransmitter binding GO:0042165 8.96 SLC6A12 SLC6A13
3 gamma-aminobutyric acid:sodium symporter activity GO:0005332 8.62 SLC6A12 SLC6A13

Sources for Traumatic Glaucoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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