MCID: TRM002
MIFTS: 25

Traumatic Glaucoma

Categories: Eye diseases

Aliases & Classifications for Traumatic Glaucoma

MalaCards integrated aliases for Traumatic Glaucoma:

Name: Traumatic Glaucoma 12 15
Glaucoma Associated with Ocular Trauma 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:13060
ICD9CM 35 365.65
SNOMED-CT 68 68241007
UMLS 73 C0339594

Summaries for Traumatic Glaucoma

MalaCards based summary : Traumatic Glaucoma, also known as glaucoma associated with ocular trauma, is related to glaucoma 1, open angle, a and chronic closed-angle glaucoma. An important gene associated with Traumatic Glaucoma is OPTN (Optineurin), and among its related pathways/superpathways are Neurotransmitter Release Cycle and Benzodiazepine Pathway, Pharmacodynamics. The drugs Triamcinolone and Hormones have been mentioned in the context of this disorder. Affiliated tissues include eye.

Related Diseases for Traumatic Glaucoma

Diseases related to Traumatic Glaucoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
# Related Disease Score Top Affiliating Genes
1 glaucoma 1, open angle, a 11.1
2 chronic closed-angle glaucoma 10.0 OPTN PHEX
3 phacogenic glaucoma 10.0 OPTN PHEX
4 low tension glaucoma 9.9 OPTN PHEX
5 iris disease 9.9 OPTN PHEX
6 juvenile glaucoma 9.9 OPTN PHEX
7 lens disease 9.9 OPTN PHEX
8 neovascular glaucoma 9.9 OPTN SLC6A13
9 uveal disease 9.8 OPTN PHEX
10 myopia 9.8
11 glaucoma, primary open angle 9.7 OPTN PHEX SLC6A13

Graphical network of the top 20 diseases related to Traumatic Glaucoma:



Diseases related to Traumatic Glaucoma

Symptoms & Phenotypes for Traumatic Glaucoma

Drugs & Therapeutics for Traumatic Glaucoma

Drugs for Traumatic Glaucoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Triamcinolone Approved, Vet_approved Phase 2, Phase 3 124-94-7 31307
2 Hormones Phase 2, Phase 3
3 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2, Phase 3
4 Triamcinolone diacetate Phase 2, Phase 3
5 triamcinolone acetonide Phase 2, Phase 3
6 Hormone Antagonists Phase 2, Phase 3
7 Anti-Inflammatory Agents Phase 2, Phase 3
8 Immunosuppressive Agents Phase 2, Phase 3
9 Immunologic Factors Phase 2, Phase 3
10 Triamcinolone hexacetonide Phase 2, Phase 3
11 Pharmaceutical Solutions Phase 2, Phase 3
12 glucocorticoids Phase 2, Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Will the Use of Triesence During Glaucoma Surgery Provide Lower Eye Pressure and Improve the Results of the Surgery? Completed NCT00853905 Phase 2, Phase 3 Triesence;balanced salt solution BSS
2 Laminar Drainage Implant: Safety of a Novel Surgical Treatment for Refractory Glaucoma. Completed NCT03166566 Not Applicable
3 Patch Graft Material Safety and Effectiveness in Covering Glaucoma Drainage Device Tube Terminated NCT01301378 Not Applicable

Search NIH Clinical Center for Traumatic Glaucoma

Genetic Tests for Traumatic Glaucoma

Anatomical Context for Traumatic Glaucoma

MalaCards organs/tissues related to Traumatic Glaucoma:

41
Eye

Publications for Traumatic Glaucoma

Articles related to Traumatic Glaucoma:

(show all 22)
# Title Authors Year
1
Optical Coherence Tomography Angiography Description of Ocular Decompression Retinopathy after Deep Sclerectomy in Traumatic Glaucoma. ( 29303876 )
2018
2
Traumatic glaucoma due to paintball injuries: A case series. ( 29270481 )
2017
3
Surgical Outcomes of Ahmed or Baerveldt Tube Shunt Implantation for medically Uncontrolled Traumatic Glaucoma. ( 28138213 )
2017
4
Transpupillary Argon Laser Cyclophotocoagulation in a Refractory Traumatic Glaucoma Patient with Aphakia and Aniridia. ( 27800256 )
2016
5
Incidence and risk factors for traumatic intraocular pressure elevation and traumatic glaucoma after open-globe injury. ( 26381097 )
2015
6
Vitreous occlusion of tube implant in a phakic patient with traumatic glaucoma. ( 25378882 )
2014
7
Traumatic Glaucoma in Children. ( 26997810 )
2014
8
Traumatic glaucoma with features of unilateral pigment dispersion. ( 25097455 )
2014
9
An unusual case of glaucoma: traumatic glaucoma probably caused by shock waves. ( 20220403 )
2010
10
Early predictors of traumatic glaucoma after closed globe injury: trabecular pigmentation, widened angle recess, and higher baseline intraocular pressure. ( 18625937 )
2008
11
Progressive axial myopia in a juvenile patient with traumatic glaucoma. ( 11992870 )
2002
12
Long-term follow-up of traumatic glaucoma treated with Molteno implants. ( 11581051 )
2001
13
Traumatic glaucoma. ( 11816998 )
2001
14
Traumatic glaucoma. ( 11711845 )
2001
15
Transpupillary argon laser cyclophotocoagulation in the treatment of traumatic glaucoma. ( 10529935 )
1999
16
Traumatic glaucoma. ( 7493239 )
1995
17
Trabecular damage due to blunt anterior segment injury and its relationship to traumatic glaucoma. ( 406709 )
1977
18
Traumatic glaucoma--the thief of sight. ( 1152637 )
1975
19
Traumatic glaucoma. ( 4825066 )
1974
20
The management of traumatic glaucoma. ( 5133221 )
1971
21
Traumatic glaucoma. ( 5607317 )
1967
22
Use of radium for traumatic glaucoma. ( 14937033 )
1952

Variations for Traumatic Glaucoma

Expression for Traumatic Glaucoma

Search GEO for disease gene expression data for Traumatic Glaucoma.

Pathways for Traumatic Glaucoma

GO Terms for Traumatic Glaucoma

Cellular components related to Traumatic Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 8.8 PHEX SLC6A12 SLC6A13

Biological processes related to Traumatic Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neurotransmitter transport GO:0006836 8.96 SLC6A12 SLC6A13
2 gamma-aminobutyric acid transport GO:0015812 8.62 SLC6A12 SLC6A13

Molecular functions related to Traumatic Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 symporter activity GO:0015293 9.16 SLC6A12 SLC6A13
2 neurotransmitter binding GO:0042165 8.96 SLC6A12 SLC6A13
3 gamma-aminobutyric acid:sodium symporter activity GO:0005332 8.62 SLC6A12 SLC6A13

Sources for Traumatic Glaucoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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