MCID: TRM003
MIFTS: 54

Tremor

Categories: Genetic diseases, Neuronal diseases, Oral diseases, Rare diseases

Aliases & Classifications for Tremor

Summaries for Tremor

MedlinePlus : 42 What is a tremor? A tremor is a rhythmic shaking movement in one or more parts of your body. It is involuntary, meaning that you cannot control it. This shaking happens because of muscle contractions. A tremor is most often in your hands, but it could also affect your arms, head, vocal cords, trunk, and legs. It may come and go, or it may be constant. Tremor can happen on its own or be caused by another disorder. What are the types of tremor? There are several types of tremor, including Essential tremor, sometimes called benign essential tremor. This is the most common type. It usually affects your hands, but it can also affect your head, voice, tongue, legs, and trunk. Parkinsonian tremor, which is a common symptom in people who have Parkinson's disease. It is usually affects one or both hands when they are at rest, but it can affect the chin, lips, face, and legs. Dystonic tremor, which happens in people who have dystonia. Dystonia is a movement disorder in which you have involuntary muscle contractions. The contractions cause you to have twisting and repetitive movements. It can affect any muscle in the body. What causes tremor? Generally, tremor is caused by a problem in the deep parts of the brain that control movements. For most types, the cause is unknown. Some types are inherited and run in families. There can also be other causes, such as Neurologic disorders, including multiple sclerosis, Parkinson's disease, stroke, and traumatic brain injury Certain medicines, such as asthma medicines, amphetamines, caffeine, corticosteroids, and medicines used for certain psychiatric and neurological disorders Alcohol use disorder or alcohol withdrawal Mercury poisoning Hyperthyroidism (overactive thyroid) Liver or kidney failure Anxiety or panic Who is at risk for tremor? Anyone can get tremor, but it is most common in middle-aged and older adults. For certain types, having a family history raises your risk of getting it. What are the symptoms of tremor? Symptoms of tremor may include Rhythmic shaking in the hands, arms, head, legs, or torso Shaky voice Difficulty writing or drawing Problems holding and controlling utensils, such as a spoon How is tremor diagnosed? To make a diagnosis, your health care provider Will take your medical history Will do a physical exam, which includes checking Whether the tremor happens when the muscles are at rest or in action The location of the tremor How often you have the tremor and how strong it is Will do a neurological exam, including checking for Problems with balance Problems with speech Increased muscle stiffness May do blood or urine tests to look for the cause May do imaging tests to help figure out if the cause is damage in your brain May do tests which check your abilities to do daily tasks such as handwriting and holding a fork or cup May do an electromyogram. This is a test which measures involuntary muscle activity and how your muscles respond to nerve stimulation What are the treatments for tremor? There is no cure for most forms of tremor, but there are treatments to help manage symptoms. In some cases, the symptoms may be so mild that you do not need treatment. Finding the right treatment depends on getting the right diagnosis of the cause. Tremor caused by another medical condition may get better or go away when you treat that condition. If your tremor is caused by a certain medicine, stopping that medicine usually makes the tremor go away. Treatments for tremor where the cause is not found include Medicines. There are different medicines for the specific types of tremor. Another option is Botox injections, which can treat several different types. Surgery may be used for severe cases that do not get better with medicines. The most common type is deep brain stimulation (DBS). Physical, speech-language, and occupational therapy, which may help to control tremor and deal with the daily challenges caused by the tremor If you find that caffeine and other stimulants trigger your tremors, it may be helpful to cut them from your diet. NIH: National Institute of Neurological Disorders and Stroke

MalaCards based summary : Tremor, also known as tremors, is related to fragile x tremor/ataxia syndrome and benign adult familial myoclonic epilepsy. An important gene associated with Tremor is C19orf12 (Chromosome 19 Open Reading Frame 12), and among its related pathways/superpathways are Neuroscience and Parkinsons Disease Pathway. The drugs Acetylcholine and Donepezil have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and subthalamic nucleus, and related phenotypes are behavior/neurological and integument

NINDS : 53 Tremor is an unintentional, rhythmic, muscle movement involving to-and-fro movements of one or more parts of the body. Most tremors occur in the hands, although they can also affect the arms, head, face, voice, torso, and legs. Generally, tremor is caused by a problem in the deep parts of the brain that control movements.  Some forms of tremor are inherited and run in families, while others have no known cause. Sometimes tremor is a symptom of another neurological disorder or a side effect of certain drugs, but the most common form occurs in otherwise healthy people. Excessive alcohol consumption or alcohol withdrawal can kill certain nerve cells, resulting in tremor, especially in the hand. Other causes include an overactive thyroid and the use of certain drugs. Tremor may occur at any age but is most common in middle-aged and older adults. There are several types of tremor, one of the most common of which is essential tremor (sometimes called benign essential tremor). The hands are most often affected but the head, voice, tongue, legs, and trunk may also be involved. Head tremor may be seen as a "yes-yes" or "no-no" motion. Onset is most common after age 40, although symptoms can appear at any age. Parkinsonian tremor is caused by damage to structures within the brain that control movement. The tremor is classically seen as a "pill-rolling" action of the hands but may also affect the chin, face, lips, and legs. Dystonic tremor occurs in individuals of all ages who are affected by dystonia, a movement disorder which causes muscles to be over-active, resulting in abnormal postures or sustained, unwanted movements.

Wikipedia : 74 A tremor is an involuntary, somewhat rhythmic, muscle contraction and relaxation involving oscillations... more...

Related Diseases for Tremor

Diseases in the Tremor family:

Tremor, Hereditary Essential, 1 Tremor, Hereditary Essential, 2
Tremor, Hereditary Essential, 3 Tremor, Hereditary Essential, 4
Tremor, Hereditary Essential, 5 Essential Tremor
Rare Tremor Disorder

Diseases related to Tremor via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 836, show less)
# Related Disease Score Top Affiliating Genes
1 fragile x tremor/ataxia syndrome 34.6 LOC108684022 FMR1
2 benign adult familial myoclonic epilepsy 32.4 SAMD12 CNTN2
3 multiple system atrophy 1 32.0 SNCA PRKN MAPT LRRK2 FMR1
4 essential tremor 31.7 TENM4 SNCA PRKN MAPT LRRK2 HTRA2
5 parkinson disease 2, autosomal recessive juvenile 31.6 SNCA PRKN LRRK2 HTRA2
6 machado-joseph disease 31.6 SNCA PRKN ATXN2
7 dystonia 31.5 PRKN LRRK2 FUS DRD3 C19orf12
8 perry syndrome 31.5 SNCA MAPT FUS
9 movement disease 31.4 SNCA PRKN MAPT LRRK2 GBA FUS
10 dementia, lewy body 31.4 SNCA PRKN MAPT LRRK2 GBA FUS
11 neurodegeneration with brain iron accumulation 31.1 SNCA PRKN LRRK2 C19orf12
12 fmr1 disorders 31.0 LOC108684022 FMR1
13 parkinson disease 15, autosomal recessive early-onset 30.9 SNCA PRKN LRRK2 C19orf12
14 aceruloplasminemia 30.7 SNCA MAPT FMR1 C19orf12 ATXN2
15 kufor-rakeb syndrome 30.7 SNCA PRKN LRRK2 C19orf12
16 amyotrophic lateral sclerosis 1 30.4 SNCA PRKN MAPT LRRK2 HTRA2 FUS
17 dysautonomia 30.3 SNCA GBA DNAJC13
18 rem sleep behavior disorder 30.2 SNCA MAPT LRRK2 GBA
19 corticobasal degeneration 30.1 MAPT LRRK2 GBA
20 neuronal intranuclear inclusion disease 30.0 SNCA MAPT
21 parkinson disease, late-onset 29.9 SNCA PRKN MAPT LRRK2 HTRA2 GBA
22 aphasia 29.9 SNCA MAPT LRRK2 FUS
23 motor neuron disease 29.8 SNCA PRKN MAPT FUS
24 olivopontocerebellar atrophy 29.8 SNCA MAPT ATXN2
25 supranuclear palsy, progressive, 1 29.6 SNCA PRKN MAPT LRRK2 FUS ATXN2
26 early-onset parkinson's disease 29.5 SNCA PRKN LRRK2 GBA DRD3
27 frontotemporal dementia 29.5 SNCA MAPT LRRK2 FUS CHCHD2
28 postencephalitic parkinson disease 29.4 SNCA PRKN MAPT LRRK2
29 autosomal dominant cerebellar ataxia 29.4 SNCA PRKN MAPT LRRK2 FUS FMR1
30 restless legs syndrome 29.2 SNCA PRKN MAPT LOC108684022 FMR1 DRD3
31 dementia 29.0 SNCA PRKN MAPT LRRK2 GBA FUS
32 frontotemporal dementia and/or amyotrophic lateral sclerosis 1 28.9 SAMD12 MAPT FUS ATXN2
33 tremor, hereditary essential, 1 12.7
34 primary orthostatic tremor 12.6
35 tremor, hereditary essential, 4 12.6
36 fragile x-associated tremor/ataxia syndrome 12.6
37 tremor, hereditary essential, 5 12.6
38 myopathy, congenital, with tremor 12.6
39 tremor, hereditary essential, 2 12.6
40 tremor, hereditary essential, 3 12.5
41 tremor, nystagmus, and duodenal ulcer 12.3
42 tremor, hereditary essential, and idiopathic normal pressure hydrocephalus 12.3
43 tremor of intention, ataxia, and lipofuscinosis 12.2
44 rare genetic tremor disorder 12.1
45 rare tremor disorder 12.1
46 sensorineural hearing loss-early graying-essential tremor syndrome 12.1
47 epilepsy, familial adult myoclonic, 5 12.1
48 epilepsy, familial adult myoclonic, 1 12.0
49 epilepsy, familial adult myoclonic, 2 12.0
50 leukodystrophy, hypomyelinating, 7, with or without oligodontia and/or hypogonadotropic hypogonadism 12.0
51 polr3-related leukodystrophy 11.9
52 epilepsy, familial adult myoclonic, 3 11.9
53 mental retardation, x-linked, syndromic, cabezas type 11.9
54 epilepsy, familial adult myoclonic, 6 11.8
55 epilepsy, familial adult myoclonic, 7 11.8
56 mental retardation, autosomal recessive 48 11.8
57 hereditary geniospasm 11.8
58 myoclonic cerebellar dyssynergia 11.7
59 psychogenic movement 11.7
60 epilepsy, familial adult myoclonic, 4 11.6
61 multiple sclerosis 11.5
62 hypertrophic olivary degeneration 11.5
63 hyperthyroidism 11.4
64 epilepsy, progressive myoclonic, 4, with or without renal failure 11.4
65 roussy-levy hereditary areflexic dystasia 11.4
66 wilson disease 11.4
67 spinal and bulbar muscular atrophy, x-linked 1 11.4
68 cerebellar degeneration 11.4
69 dystonia 1, torsion, autosomal dominant 11.4
70 spinocerebellar ataxia 2 11.4
71 graves' disease 11.4
72 spinal muscular atrophy 11.4
73 spinocerebellar ataxia 6 11.3
74 pelizaeus-merzbacher disease 11.3
75 central pontine myelinolysis 11.3
76 48,xxyy syndrome 11.3
77 cervical dystonia 11.3
78 neurodegeneration with brain iron accumulation 3 11.3
79 japanese encephalitis 11.3
80 dystonia 11, myoclonic 11.3
81 spinocerebellar ataxia 12 11.3
82 parkinson disease 21 11.3
83 west nile encephalitis 11.3
84 deep brain stimulation for movement disorders 11.3
85 focal dystonia 11.3
86 47,xyy 11.2
87 leukoencephalopathy with dystonia and motor neuropathy 11.2
88 charcot-marie-tooth disease 11.2
89 hypogonadotropic hypogonadism 11.2
90 schizophrenia 11.2
91 cerebral palsy 11.2
92 basal ganglia calcification, idiopathic, 1 11.2
93 abetalipoproteinemia 11.2
94 mercury poisoning 11.2
95 angelman syndrome 11.2
96 spinocerebellar ataxia 1 11.2
97 parkinson disease 4, autosomal dominant 11.2
98 parkinson disease 11, autosomal dominant 11.2
99 cerebral beriberi 11.2
100 serotonin syndrome 11.2
101 neuroaxonal dystrophy renal tubular acidosis 11.1
102 spinocerebellar ataxia 29 11.1
103 dystonia 3, torsion, x-linked 11.1
104 leukodystrophy, hypomyelinating, 2 11.1
105 spinocerebellar ataxia 27 11.1
106 parkinsonism-dystonia, infantile, 1 11.1
107 hypermanganesemia with dystonia 11.1
108 ramsay hunt syndrome i 11.1
109 spinocerebellar ataxia 31 11.0
110 dystonia, dopa-responsive 11.0
111 spinal muscular atrophy with progressive myoclonic epilepsy 11.0
112 optic atrophy 3, autosomal dominant 11.0
113 parkinson disease 1, autosomal dominant 11.0
114 agenesis of the corpus callosum with peripheral neuropathy 11.0
115 neurodegeneration with brain iron accumulation 5 11.0
116 anemia, sideroblastic, and spinocerebellar ataxia 11.0
117 leber optic atrophy 11.0
118 cerebellar ataxia, cayman type 11.0
119 nemaline myopathy 5 11.0
120 parkinson disease 7, autosomal recessive early-onset 11.0
121 blepharospasm, benign essential 11.0
122 spinocerebellar ataxia 21 11.0
123 spinocerebellar ataxia 35 11.0
124 triosephosphate isomerase deficiency 11.0
125 parkinson disease 19a, juvenile-onset 11.0
126 myopathy with extrapyramidal signs 11.0
127 spinocerebellar ataxia 40 11.0
128 spastic paraplegia 9b, autosomal recessive 11.0
129 developmental delay and seizures with or without movement abnormalities 11.0
130 leukodystrophy, hypomyelinating, 16 11.0
131 neurodevelopmental disorder with impaired speech and hyperkinetic movements 11.0
132 spinocerebellar ataxia type 19/22 11.0
133 unverricht-lundborg syndrome 11.0
134 von economo's disease 11.0
135 adcy5-related dyskinesia 11.0
136 autosomal dominant leukodystrophy with autonomic disease 11.0
137 ataxia and polyneuropathy, adult-onset 11.0
138 cerebral amyloid angiopathy, itm2b-related, 2 10.9
139 dystonia 12 10.9
140 cockayne syndrome b 10.9
141 myopathy, distal, 1 10.9
142 ceroid lipofuscinosis, neuronal, 4b, autosomal dominant 10.9
143 mccune-albright syndrome 10.9
144 cerebral amyloid angiopathy, itm2b-related, 1 10.9
145 gillespie syndrome 10.9
146 argininemia 10.9
147 argininosuccinic aciduria 10.9
148 cerebellar ataxia, early-onset, with retained tendon reflexes 10.9
149 chediak-higashi syndrome 10.9
150 cockayne syndrome a 10.9
151 leukoencephalopathy, hereditary diffuse, with spheroids 10.9
152 glutathionuria 10.9
153 kuru 10.9
154 megalocornea 10.9
155 metachromatic leukodystrophy 10.9
156 parkinson-dementia syndrome 10.9
157 hyperphenylalaninemia, bh4-deficient, d 10.9
158 wiedemann-rautenstrauch syndrome 10.9
159 spinocerebellar degeneration and corneal dystrophy 10.9
160 sudanophilic cerebral sclerosis 10.9
161 wernicke-korsakoff syndrome 10.9
162 mental retardation, x-linked, syndromic 13 10.9
163 brunner syndrome 10.9
164 phosphoglycerate kinase 1 deficiency 10.9
165 parkinsonism with spasticity, x-linked 10.9
166 mental retardation, x-linked 12 10.9
167 spinocerebellar ataxia, x-linked 4 10.9
168 partington x-linked mental retardation syndrome 10.9
169 charcot-marie-tooth disease, x-linked recessive, 4, with or without cerebellar ataxia 10.9
170 waisman syndrome 10.9
171 spastic paraparesis and deafness 10.9
172 spastic paraplegia 2, x-linked 10.9
173 leber optic atrophy and dystonia 10.9
174 hypomagnesemia 1, intestinal 10.9
175 myotonic dystrophy 2 10.9
176 spinocerebellar ataxia 10 10.9
177 congenital cataracts, facial dysmorphism, and neuropathy 10.9
178 cerebral palsy, ataxic, autosomal recessive 10.9
179 segawa syndrome, autosomal recessive 10.9
180 parkinson disease 6, autosomal recessive early-onset 10.9
181 spinocerebellar ataxia 15 10.9
182 parkinson disease 8, autosomal dominant 10.9
183 spinocerebellar ataxia 19 10.9
184 dystonia, juvenile-onset 10.9
185 spinocerebellar ataxia 20 10.9
186 striatal degeneration, autosomal dominant 1 10.9
187 parkinson disease 13, autosomal dominant 10.9
188 dystonia, focal, task-specific 10.9
189 dystonia 16 10.9
190 dystonia, dopa-responsive, due to sepiapterin reductase deficiency 10.9
191 cerebral creatine deficiency syndrome 2 10.9
192 parkinson disease 14, autosomal recessive 10.9
193 neurodegeneration due to cerebral folate transport deficiency 10.9
194 nephronophthisis-like nephropathy 1 10.9
195 parkinson disease 5, autosomal dominant 10.9
196 parkinson disease 17 10.9
197 parkinson disease 18, autosomal dominant 10.9
198 basal ganglia calcification, idiopathic, 4 10.9
199 basal ganglia calcification, idiopathic, 5 10.9
200 parkinson disease 20, early-onset 10.9
201 encephalopathy, progressive, with or without lipodystrophy 10.9
202 basal ganglia calcification, idiopathic, 6 10.9
203 leukodystrophy, hypomyelinating, 11 10.9
204 parkinson disease 22, autosomal dominant 10.9
205 parkinson disease 23, autosomal recessive early-onset 10.9
206 jaberi-elahi syndrome 10.9
207 basal ganglia calcification, idiopathic, 7, autosomal recessive 10.9
208 powassan encephalitis 10.9
209 syndromic x-linked intellectual disability cabezas type 10.9
210 primary hypomagnesemia 10.9
211 sleeping sickness 10.9
212 louping ill 10.9
213 st. louis encephalitis 10.9
214 thyroid crisis 10.9
215 cockayne syndrome 10.9
216 glycoproteinosis 10.9
217 striatonigral degeneration 10.9
218 grn-related frontotemporal dementia 10.9
219 mitochondrial membrane protein-associated neurodegeneration 10.9
220 adult neuronal ceroid lipofuscinosis 10.9
221 aids dementia complex 10.9
222 chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids 10.9
223 cockayne syndrome type iii 10.9
224 karak syndrome 10.9
225 spastic paraplegia 15 10.9
226 alg1-congenital disorder of glycosylation 10.9
227 cask-related intellectual disability 10.9
228 chmp2b-related frontotemporal dementia 10.9
229 cln4 disease 10.9
230 frontotemporal dementia with parkinsonism-17 10.9
231 extrapontine myelinolysis 10.9
232 korsakoff's amnesic syndrome 10.9
233 multiple system atrophy with orthostatic hypotension 10.9
234 myelinoclastic diffuse sclerosis 10.9
235 myoclonus 10.7
236 neuropathy 10.5
237 fragile x syndrome 10.5
238 rare surgical neurologic disease 10.5
239 peripheral nervous system disease 10.4
240 pathologic nystagmus 10.4
241 torticollis 10.4
242 epilepsy 10.4
243 spasmodic dysphonia 10.4
244 cerebellar disease 10.4
245 obsolete: laryngeal dyskinesia 10.4
246 encephalopathy 10.4
247 autonomic dysfunction 10.4
248 seizure disorder 10.4
249 visual epilepsy 10.3
250 alcohol dependence 10.3
251 migraine with or without aura 1 10.3
252 paresthesia 10.3
253 chorea, childhood-onset, with psychomotor retardation 10.3
254 choreatic disease 10.3
255 cerebrovascular disease 10.3
256 muscular atrophy 10.3
257 lateral sclerosis 10.3
258 primary lateral sclerosis, adult, 1 10.3 SNCA MAPT
259 tardive dyskinesia 10.3
260 stroke, ischemic 10.3
261 polyneuropathy 10.3
262 nominal aphasia 10.2 MAPT FUS
263 chronic tic disorder 10.2 DRD3 DNAJC13
264 kearns-sayre syndrome 10.2
265 tic disorder 10.2
266 spasticity 10.2
267 huntington disease 10.2
268 lrrk2 parkinson disease 10.2 SNCA PRKN LRRK2
269 alexander disease 10.2
270 hydrocephalus 10.2
271 parkinson disease 10 10.2 SNCA PRKN LRRK2
272 spinocerebellar ataxia 37 10.2 SNCA SAMD12
273 alzheimer disease 10.2
274 anxiety 10.2
275 myopathy 10.2
276 depression 10.2
277 coenzyme q10 deficiency, primary, 1 10.2 SNCA MAPT
278 vitamin b12 deficiency 10.2
279 chronic inflammatory demyelinating polyradiculoneuropathy 10.2
280 encephalitis 10.2
281 cerebral atrophy 10.2
282 dysphagia 10.2
283 head injury 10.2
284 headache 10.2
285 rare movement disorder 10.2
286 tooth disease 10.1
287 blepharospasm 10.1
288 pontine hemorrhage 10.1
289 hypotonia 10.1
290 gaucher's disease 10.1 SNCA PRKN GBA
291 hand skill, relative 10.1
292 graves disease 1 10.1
293 aging 10.1
294 meningioma, radiation-induced 10.1
295 meningioma, familial 10.1
296 segmental dystonia 10.1
297 leukodystrophy 10.1
298 social phobia 10.1
299 spinal meningioma 10.1
300 hepatic encephalopathy 10.1
301 hypothyroidism 10.1
302 alcohol use disorder 10.1
303 secretory meningioma 10.1
304 lymphoplasmacyte-rich meningioma 10.1
305 sleep disorder 10.1
306 athetosis 10.1
307 seizures, benign familial neonatal, 1 10.1
308 premature ovarian failure 1 10.1
309 alacrima, achalasia, and mental retardation syndrome 10.1
310 hepatic coma 10.1
311 personality disorder 10.1
312 constipation 10.1
313 astrocytoma 10.1
314 polyradiculoneuropathy 10.1
315 demyelinating polyneuropathy 10.1
316 charcot-marie-tooth disease, x-linked recessive, 2 10.1 SNCA MPZ
317 echolalia 10.1 MAPT FMR1
318 pervasive developmental disorder 10.1 SNCA LOC108684022 FMR1 DRD3
319 cerebellar hypoplasia 10.0
320 ocular motor apraxia 10.0
321 hemiplegia 10.0
322 diarrhea 10.0
323 vascular disease 10.0
324 early myoclonic encephalopathy 10.0
325 liver cirrhosis 10.0
326 progressive multifocal leukoencephalopathy 10.0
327 48,xyyy 10.0
328 glioma 10.0
329 glial tumor 10.0
330 isolated dystonia 10.0
331 gilles de la tourette syndrome 10.0
332 obsessive-compulsive disorder 10.0
333 arachnoid cysts, intracranial 10.0
334 neurodegeneration with brain iron accumulation 1 10.0
335 canavan disease 10.0
336 withdrawal disorder 10.0
337 apraxia 10.0
338 pain agnosia 10.0
339 arteriovenous malformation 10.0
340 generalized anxiety disorder 10.0
341 avoidant personality disorder 10.0
342 mood disorder 10.0
343 internuclear ophthalmoplegia 10.0
344 paraplegia 10.0
345 severe combined immunodeficiency 10.0
346 acquired immunodeficiency syndrome 10.0
347 47, xxy 10.0
348 sphingolipidosis 10.0 SNCA PRKN LRRK2 GBA
349 hereditary late-onset parkinson disease 10.0 SNCA LRRK2 GBA DNAJC13
350 amyotrophic lateral sclerosis 21 10.0 FUS ATXN2
351 disease of mental health 10.0 SNCA MAPT FMR1 DRD3
352 specific developmental disorder 10.0 MAPT FMR1 DRD3
353 immune deficiency disease 10.0
354 major affective disorder 8 10.0
355 major affective disorder 9 10.0
356 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.0
357 multifocal dystonia 10.0
358 autism spectrum disorder 10.0
359 chronic progressive external ophthalmoplegia 10.0
360 somatization disorder 10.0
361 benign shuddering attacks 10.0
362 demyelinating disease 10.0
363 bipolar disorder 10.0
364 agnosia 10.0
365 benign ependymoma 10.0
366 cellular ependymoma 10.0
367 bronchitis 10.0
368 learning disability 10.0
369 hereditary dystonia 10.0
370 hemiplegic migraine 10.0
371 myoclonus epilepsy 10.0
372 spinocerebellar degeneration 10.0
373 traumatic brain injury 10.0
374 parkinson disease 3, autosomal dominant 10.0 SNCA PRKN MAPT LRRK2
375 toxic encephalopathy 9.9 SNCA PRKN MAPT LRRK2
376 autoimmune disease 9.9
377 hemifacial spasm, familial 9.9
378 stiff-person syndrome 9.9
379 strabismus 9.9
380 celiac disease 1 9.9
381 friedreich ataxia 9.9
382 hydrocephalus, normal-pressure 9.9
383 epilepsy, myoclonic juvenile 9.9
384 3-methylglutaconic aciduria, type iii 9.9
385 phenylketonuria 9.9
386 retinitis pigmentosa 9.9
387 reflex sympathetic dystrophy 9.9
388 body mass index quantitative trait locus 1 9.9
389 human immunodeficiency virus type 1 9.9
390 hemidystonia 9.9
391 hereditary ataxia 9.9
392 stuttering 9.9
393 ptosis 9.9
394 sensorineural hearing loss 9.9
395 neuroretinitis 9.9
396 allergic hypersensitivity disease 9.9
397 algoneurodystrophy 9.9
398 mental depression 9.9
399 conversion disorder 9.9
400 status epilepticus 9.9
401 hemangioma 9.9
402 substance abuse 9.9
403 neurilemmoma 9.9
404 germinoma 9.9
405 brain stem infarction 9.9
406 retinitis 9.9
407 liver disease 9.9
408 intracranial hypotension 9.9
409 poliomyelitis 9.9
410 infertility 9.9
411 scrapie 9.9
412 kidney disease 9.9
413 congestive heart failure 9.9
414 juvenile pilocytic astrocytoma 9.9
415 thyroiditis 9.9
416 axonal neuropathy 9.9
417 cataract 9.9
418 subacute delirium 9.9
419 mechanical strabismus 9.9
420 fetal methylmercury syndrome 9.9
421 paraneoplastic cerebellar degeneration 9.9
422 spastic paraparesis 9.9
423 hemifacial spasm 9.9
424 hypoxia 9.9
425 specific language disorder 9.9
426 spontaneous intracranial hypotension 9.9
427 pitt-hopkins-like syndrome 1 9.9 FMR1 CNTN2
428 mitochondrial complex i deficiency, nuclear type 1 9.8 SNCA PRKN LRRK2 HTRA2
429 gastroesophageal reflux 9.8
430 creutzfeldt-jakob disease 9.8
431 dentatorubral-pallidoluysian atrophy 9.8
432 major affective disorder 1 9.8
433 epidermoid cysts 9.8
434 hashimoto thyroiditis 9.8
435 migraine, familial hemiplegic, 1 9.8
436 mirror movements 1 9.8
437 hypokalemic periodic paralysis, type 1 9.8
438 syringomyelia, noncommunicating isolated 9.8
439 geniospasm 1 9.8
440 ataxia-telangiectasia 9.8
441 autism 9.8
442 congenital heart defects, hamartomas of tongue, and polysyndactyly 9.8
443 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 9.8
444 hydrocephalus due to congenital stenosis of aqueduct of sylvius 9.8
445 myasthenia gravis 9.8
446 myeloma, multiple 9.8
447 body mass index quantitative trait locus 11 9.8
448 branchiootic syndrome 1 9.8
449 apraxia of eyelid opening 9.8
450 spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2 9.8
451 coronary heart disease 1 9.8
452 major depressive disorder 9.8
453 aplastic anemia 9.8
454 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 9.8
455 cavitary optic disc anomalies 9.8
456 glut1 deficiency syndrome 2 9.8
457 diabetes mellitus, ketosis-prone 9.8
458 pulmonary fibrosis and/or bone marrow failure, telomere-related, 2 9.8
459 dystonia 25 9.8
460 carbonic anhydrase va deficiency, hyperammonemia due to 9.8
461 striatal degeneration, autosomal dominant 2 9.8
462 hydrops, lactic acidosis, and sideroblastic anemia 9.8
463 deficiency anemia 9.8
464 2-hydroxyglutaric aciduria 9.8
465 early infantile epileptic encephalopathy 9.8
466 familial hemiplegic migraine 9.8
467 atrial fibrillation 9.8
468 scoliosis 9.8
469 physical disorder 9.8
470 siderosis 9.8
471 lymphocytic leukemia 9.8
472 sarcoma 9.8
473 infant gynecomastia 9.8
474 lyme disease 9.8
475 protein-energy malnutrition 9.8
476 acoustic neuroma 9.8
477 locked-in syndrome 9.8
478 gynecomastia 9.8
479 telangiectasis 9.8
480 guillain-barre syndrome 9.8
481 dissociated nystagmus 9.8
482 megaloblastic anemia 9.8
483 neurosarcoidosis 9.8
484 multiple cranial nerve palsy 9.8
485 niemann-pick disease 9.8
486 cholera 9.8
487 neuritis 9.8
488 impotence 9.8
489 melanoma 9.8
490 hypogonadism 9.8
491 neuroma 9.8
492 post-traumatic stress disorder 9.8
493 focal epilepsy 9.8
494 hereditary spastic paraplegia 9.8
495 sensory peripheral neuropathy 9.8
496 bruxism 9.8
497 adenocarcinoma 9.8
498 syringomyelia 9.8
499 histrionic personality disorder 9.8
500 liposarcoma 9.8
501 hyperglycemia 9.8
502 spindle cell sarcoma 9.8
503 neuromuscular disease 9.8
504 anterior horn cell disease 9.8
505 acute stress disorder 9.8
506 basal ganglia disease 9.8
507 monoclonal gammopathy of uncertain significance 9.8
508 hypogonadotropism 9.8
509 malignant hyperthermia 9.8
510 vasculitis 9.8
511 mitochondrial encephalomyopathy 9.8
512 progressive myoclonus epilepsy 9.8
513 speech disorder 9.8
514 waardenburg's syndrome 9.8
515 exophthalmos 9.8
516 episodic ataxia 9.8
517 refractive error 9.8
518 lingual-facial-buccal dyskinesia 9.8
519 muscular dystrophy 9.8
520 toxoplasmosis 9.8
521 parkin type of early-onset parkinson disease 9.8
522 sgce myoclonus-dystonia 9.8
523 stxbp1 encephalopathy with epilepsy 9.8
524 bobble-head doll syndrome 9.8
525 drug induced dyskinesia 9.8
526 granulocytopenia 9.8
527 brain injury 9.8
528 dementia - subcortical 9.8
529 hereditary neuropathies 9.8
530 hypertonia 9.8
531 ohtahara syndrome 9.8
532 spinal cord injury 9.8
533 audiogenic seizures 9.8
534 posttransplant acute limbic encephalitis 9.8
535 rare neurodegenerative disease 9.8
536 rapidly involuting congenital hemangioma 9.8
537 superficial siderosis 9.8
538 spasmus nutans 9.8
539 periodic paralysis 9.8
540 early-onset generalized limb-onset dystonia 9.8
541 benign idiopathic neonatal seizures 9.8
542 premature aging 9.8
543 oculomotor apraxia 9.8
544 amyotrophic lateral sclerosis 10 with or without frontotemporal dementia 9.8 FUS ATXN2
545 pick disease of brain 9.8 SNCA PRKN MAPT LRRK2 FUS
546 episodic ataxia, type 2 9.7
547 breast cancer 9.7
548 colorectal cancer 9.7
549 hepatocellular carcinoma 9.7
550 carpal tunnel syndrome 9.7
551 sotos syndrome 1 9.7
552 chorea, benign hereditary 9.7
553 coumarin resistance 9.7
554 discrimination, two-point, reduction in 9.7
555 erythermalgia, primary 9.7
556 facial spasm 9.7
557 fibrosis of extraocular muscles, congenital, 1 9.7
558 hirschsprung disease 1 9.7
559 attention deficit-hyperactivity disorder 9.7
560 hypercholesterolemia, familial, 1 9.7
561 inclusion body myositis 9.7
562 kabuki syndrome 1 9.7
563 systemic lupus erythematosus 9.7
564 myoclonus and ataxia 9.7
565 myositis 9.7
566 hyperkalemic periodic paralysis 9.7
567 prostate cancer 9.7
568 proteus syndrome 9.7
569 dowling-degos disease 1 9.7
570 retinal detachment 9.7
571 rheumatoid arthritis 9.7
572 sarcoidosis 1 9.7
573 small cell cancer of the lung 9.7
574 chromosome 2q35 duplication syndrome 9.7
575 thrombophilia due to thrombin defect 9.7
576 trigeminal neuralgia 9.7
577 down syndrome 9.7
578 mitochondrial dna depletion syndrome 4a 9.7
579 anemia, hypochromic microcytic, with iron overload 1 9.7
580 chiari malformation type ii 9.7
581 ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia 9.7
582 behr syndrome 9.7
583 lung cancer 9.7
584 cerebrotendinous xanthomatosis 9.7
585 bile acid synthesis defect, congenital, 4 9.7
586 yunis-varon syndrome 9.7
587 cystic fibrosis 9.7
588 l-2-hydroxyglutaric aciduria 9.7
589 hypoascorbemia 9.7
590 woodhouse-sakati syndrome 9.7
591 krabbe disease 9.7
592 chylomicron retention disease 9.7
593 myoclonic epilepsy of unverricht and lundborg 9.7
594 niemann-pick disease, type a 9.7
595 niemann-pick disease, type c1 9.7
596 pancreatic cancer 9.7
597 papilloma of choroid plexus 9.7
598 polycythemia vera 9.7
599 rett syndrome 9.7
600 helicobacter pylori infection 9.7
601 asthma 9.7
602 suppression of tumorigenicity 12 9.7
603 yemenite deaf-blind hypopigmentation syndrome 9.7
604 body mass index quantitative trait locus 9 9.7
605 xanthomatosis 9.7
606 migraine, familial hemiplegic, 2 9.7
607 macular degeneration, age-related, 1 9.7
608 body mass index quantitative trait locus 8 9.7
609 spastic paraplegia 11, autosomal recessive 9.7
610 orthostatic intolerance 9.7
611 spinocerebellar ataxia 14 9.7
612 gastrointestinal stromal tumor 9.7
613 spinocerebellar ataxia 17 9.7
614 resting heart rate, variation in 9.7
615 body mass index quantitative trait locus 4 9.7
616 body mass index quantitative trait locus 10 9.7
617 amyotrophic lateral sclerosis 6 with or without frontotemporal dementia 9.7
618 body mass index quantitative trait locus 7 9.7
619 spinocerebellar ataxia 8 9.7
620 migraine, familial hemiplegic, 3 9.7
621 spastic paraplegia 31, autosomal dominant 9.7
622 west nile virus 9.7
623 malaria 9.7
624 hamamy syndrome 9.7
625 charcot-marie-tooth disease, type 4j 9.7
626 body mass index quantitative trait locus 12 9.7
627 body mass index quantitative trait locus 14 9.7
628 parkinson disease 16 9.7
629 fatty liver disease, nonalcoholic 1 9.7
630 spinocerebellar ataxia 36 9.7
631 muscle hypertrophy 9.7
632 alpha-methylacyl-coa racemase deficiency 9.7
633 dystonia 24 9.7
634 spinocerebellar ataxia, autosomal recessive 14 9.7
635 body mass index quantitative trait locus 18 9.7
636 spinocerebellar ataxia 42 9.7
637 alkuraya-kucinskas syndrome 9.7
638 body mass index quantitative trait locus 19 9.7
639 phenytoin toxicity 9.7
640 gastrointestinal ulceration, recurrent, with dysfunctional platelets 9.7
641 body mass index quantitative trait locus 20 9.7
642 west syndrome 9.7
643 exanthem 9.7
644 inflammatory bowel disease 9.7
645 hypochromic microcytic anemia 9.7
646 autosomal recessive disease 9.7
647 oculogyric crisis 9.7
648 spasmodic dystonia 9.7
649 sleep apnea 9.7
650 spastic ataxia 9.7
651 hypomyelinating leukoencephalopathy 9.7
652 lymphoma 9.7
653 basal ganglia calcification 9.7
654 hyperekplexia 9.7
655 miyoshi muscular dystrophy 9.7
656 muscular disease 9.7
657 asymptomatic neurosyphilis 9.7
658 cysticercosis 9.7
659 endocarditis 9.7
660 portal hypertension 9.7
661 fourth cranial nerve palsy 9.7
662 obsessive-compulsive personality disorder 9.7
663 dissociative disorder 9.7
664 spastic diplegia 9.7
665 brucellosis 9.7
666 respiratory failure 9.7
667 erysipelas 9.7
668 tetanus 9.7
669 pneumocystosis 9.7
670 megacolon 9.7
671 heart disease 9.7
672 autonomic neuropathy 9.7
673 dysgammaglobulinemia 9.7
674 clubfoot 9.7
675 conn's syndrome 9.7
676 dysthymic disorder 9.7
677 neurogenic bladder 9.7
678 low compliance bladder 9.7
679 aseptic meningitis 9.7
680 neutropenia 9.7
681 bell's palsy 9.7
682 acute leukemia 9.7
683 pseudobulbar palsy 9.7
684 cerebral atherosclerosis 9.7
685 migraine without aura 9.7
686 quadriplegia 9.7
687 plasmodium vivax malaria 9.7
688 carotid stenosis 9.7
689 acute cystitis 9.7
690 ehlers-danlos syndrome 9.7
691 basilar artery occlusion 9.7
692 kwashiorkor 9.7
693 beriberi 9.7
694 squamous cell papilloma 9.7
695 facial paralysis 9.7
696 alcoholic liver cirrhosis 9.7
697 obstructive hydrocephalus 9.7
698 neuroleptic malignant syndrome 9.7
699 dumping syndrome 9.7
700 rheumatic disease 9.7
701 ichthyosis 9.7
702 cannabis dependence 9.7
703 optic nerve disease 9.7
704 enthesopathy 9.7
705 brain germinoma 9.7
706 thrombocytosis 9.7
707 transient cerebral ischemia 9.7
708 leptospirosis 9.7
709 arteriosclerosis 9.7
710 iron metabolism disease 9.7
711 west nile fever 9.7
712 relapsing-remitting multiple sclerosis 9.7
713 wernicke encephalopathy 9.7
714 papilloma 9.7
715 dermoid cyst 9.7
716 cystic teratoma 9.7
717 glioblastoma multiforme 9.7
718 thoracic outlet syndrome 9.7
719 lipid metabolism disorder 9.7
720 progressive muscular atrophy 9.7
721 oligodendroglioma 9.7
722 myelitis 9.7
723 complex regional pain syndrome 9.7
724 ischemia 9.7
725 gm2 gangliosidosis 9.7
726 temporal lobe epilepsy 9.7
727 duodenal obstruction 9.7
728 lactic acidosis 9.7
729 skin disease 9.7
730 gastric adenocarcinoma 9.7
731 cranial nerve palsy 9.7
732 posterior cerebral artery infarction 9.7
733 pancreatic adenocarcinoma 9.7
734 mutism 9.7
735 akinetic mutism 9.7
736 radiculopathy 9.7
737 erdheim-chester disease 9.7
738 central nervous system germinoma 9.7
739 hypokalemia 9.7
740 dysgraphia 9.7
741 ulnar neuropathy 9.7
742 cavernous hemangioma 9.7
743 pilocytic astrocytoma of cerebellum 9.7
744 neurotic disorder 9.7
745 pneumonia 9.7
746 mature teratoma 9.7
747 panic disorder 9.7
748 cerebral meningioma 9.7
749 viral encephalitis 9.7
750 fibrillary astrocytoma 9.7
751 b-cell lymphoma 9.7
752 neuroblastoma 9.7
753 laryngeal disease 9.7
754 frontal convexity meningioma 9.7
755 cocaine abuse 9.7
756 peritonitis 9.7
757 polycythemia 9.7
758 intestinal obstruction 9.7
759 pellagra 9.7
760 retinal degeneration 9.7
761 arthritis 9.7
762 night blindness 9.7
763 chronic fatigue syndrome 9.7
764 herpes simplex 9.7
765 nervous system disease 9.7
766 crohn's disease 9.7
767 lupus erythematosus 9.7
768 narcolepsy 9.7
769 macroglobulinemia 9.7
770 primary cerebellar degeneration 9.7
771 hypopituitarism 9.7
772 intracranial hypertension 9.7
773 pulmonary embolism 9.7
774 congenital nystagmus 9.7
775 pulmonary emphysema 9.7
776 hemorrhoid 9.7
777 irritable bowel syndrome 9.7
778 miliary tuberculosis 9.7
779 cocaine dependence 9.7
780 eosinophilia-myalgia syndrome 9.7
781 hypereosinophilic syndrome 9.7
782 hypoglycemia 9.7
783 microcephaly 9.7
784 adult polyglucosan body disease 9.7
785 glucose transporter type 1 deficiency syndrome 9.7
786 nkx2-1-related disorders 9.7
787 allergic encephalomyelitis 9.7
788 amyloid neuropathy 9.7
789 anaplastic oligodendroglioma 9.7
790 central pain syndrome 9.7
791 chiari malformation 9.7
792 chromosomal triplication 9.7
793 diaphragmatic flutter 9.7
794 gangliosidosis 9.7
795 herpes simplex encephalitis 9.7
796 juvenile amyotrophic lateral sclerosis 9.7
797 limbic encephalitis 9.7
798 multifocal motor neuropathy 9.7
799 neurosyphilis 9.7
800 paroxysmal exertion-induced dyskinesia 9.7
801 periodontal ehlers-danlos syndrome 9.7
802 pineal cyst 9.7
803 pure autonomic failure 9.7
804 sandifer syndrome 9.7
805 transverse myelitis 9.7
806 wallerian degeneration 9.7
807 aneurysm 9.7
808 anoxia 9.7
809 back pain 9.7
810 cavernous malformation 9.7
811 cerebral arteriosclerosis 9.7
812 cumulative trauma disorders 9.7
813 overuse syndrome 9.7
814 paroxysmal choreoathetosis 9.7
815 repetitive motion disorders 9.7
816 spinocerebellar atrophy 9.7
817 whiplash 9.7
818 paroxysmal dystonia 9.7
819 paroxysmal dyskinesia 9.7
820 perioral myoclonia with absences 9.7
821 trisomy 1q 9.7
822 multiple system atrophy, cerebellar type 9.7
823 disorder of copper metabolism 9.7
824 rare paroxysmal movement disorder 9.7
825 manganese poisoning 9.7
826 rare hyperkinetic movement disorder 9.7
827 congenital amyoplasia 9.7
828 bickerstaff brainstem encephalitis 9.7
829 primary lymphedema 9.7
830 lymphedema 9.7
831 early-onset schizophrenia 9.7
832 overgrowth syndrome 9.7
833 multiple system atrophy, parkinsonian type 9.7
834 rare epilepsy 9.7
835 precursor t-cell acute lymphoblastic leukemia 9.7
836 juvenile-onset parkinson's disease 9.6 SNCA PRKN LRRK2 C19orf12

Graphical network of the top 20 diseases related to Tremor:



Diseases related to Tremor

Symptoms & Phenotypes for Tremor

MGI Mouse Phenotypes related to Tremor:

45 (showing 3, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.93 ATXN2 CNTN2 DRD3 FMR1 GBA HTRA2
2 integument MP:0010771 9.56 FMR1 GBA HTRA2 LRRK2 MAPT MPZ
3 nervous system MP:0003631 9.44 ATXN2 CNTN2 DRD3 FMR1 GBA HTRA2

Drugs & Therapeutics for Tremor

Drugs for Tremor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 386, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved, Investigational Phase 4 51-84-3 187
2
Donepezil Approved Phase 4 120014-06-4 3152
3
Carbidopa Approved Phase 4 28860-95-9 34359
4
Levodopa Approved Phase 4 59-92-7 6047
5
Pramipexole Approved, Investigational Phase 4 104632-26-0 59868 119570
6
Pregabalin Approved, Investigational Phase 4 148553-50-8 5486971
7
Memantine Approved, Investigational Phase 4 19982-08-2 4054
8
Levetiracetam Approved Phase 4 102767-28-2 441341
9
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
10
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
11
Clozapine Approved Phase 4 5786-21-0 2818
12
Aripiprazole Approved, Investigational Phase 4 129722-12-9 60795
13
Methadone Approved Phase 4 76-99-3 4095
14
Entacapone Approved, Investigational Phase 4 130929-57-6 5281081
15
Sirolimus Approved, Investigational Phase 4 53123-88-9 5284616 6436030 46835353
16
Morphine Approved, Investigational Phase 4 57-27-2 5288826
17
Apomorphine Approved, Investigational Phase 4 41372-20-7, 58-00-4 6005
18
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
19
Racepinephrine Approved Phase 4 329-65-7 838
20
Lubiprostone Approved, Investigational Phase 4 136790-76-6 656719
21
Amantadine Approved Phase 4 768-94-5 2130
22
Nicotine Approved Phase 4 54-11-5 942 89594
23
Rosiglitazone Approved, Investigational Phase 4 122320-73-4 77999
24
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
25
Polyestradiol phosphate Approved Phase 4 28014-46-2
26
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
27
Cefpirome Approved Phase 4 84957-29-9 5479539
28
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
29
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
30
Selegiline Approved, Investigational, Vet_approved Phase 4 14611-51-9 5195 26757
31
Trimethobenzamide Approved, Investigational Phase 4 138-56-7 5577
32
Bupropion Approved Phase 4 34841-39-9, 34911-55-2 444
33
4-Aminopyridine Approved Phase 4 504-24-5 1727
34
Ziprasidone Approved Phase 4 146939-27-7 60854
35
Histamine Approved, Investigational Phase 4 51-45-6 774
36
Sertraline Approved Phase 4 79617-96-2 68617
37
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
38
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
39
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 5311068 68602
40
Acetaminophen Approved Phase 4 103-90-2 1983
41
Prilocaine Approved Phase 4 721-50-6 4906
42
Ketorolac Approved Phase 4 66635-83-4, 74103-06-3 3826
43
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
44
Remifentanil Approved Phase 4 132875-61-7 60815
45
Sotalol Approved Phase 4 3930-20-9, 959-24-0 5253
46
Iodine Approved, Investigational Phase 4 7553-56-2 807
47
tannic acid Approved Phase 4 1401-55-4
48
Benzocaine Approved, Investigational Phase 4 94-09-7, 1994-09-7 2337