Aliases & Classifications for Trichilemmal Cyst 1

MalaCards integrated aliases for Trichilemmal Cyst 1:

Name: Trichilemmal Cyst 1 57 13 73
Tricholemmal Cyst 57
Pilar Tumor 73
Pilar Cyst 57
Tricy1 57

Characteristics:

OMIM:

57
Inheritance:
autosomal dominant

Miscellaneous:
onset usually in adolescence


HPO:

32
trichilemmal cyst 1:
Inheritance autosomal dominant inheritance


External Ids:

OMIM 57 609649
MedGen 42 C1864801
SNOMED-CT via HPO 69 263681008 199879009 95320005

Summaries for Trichilemmal Cyst 1

OMIM : 57 Trichilemmal cysts, also known as pilar cysts or tricholemmal cysts, are derived from the outer root sheath of the deeper parts of a hair follicle and consist of a well-keratinized epidermal wall surrounding semisolid hair keratin. They occur predominantly on the scalp, are easily enucleated, and appear as a firm, smooth, white-walled cyst without a punctum (McGavran and Binnington, 1966; Pinkus, 1969; Leppard and Sanderson, 1976). (609649)

MalaCards based summary : Trichilemmal Cyst 1, also known as tricholemmal cyst, is related to proliferating trichilemmal cyst and dowling-degos disease. An important gene associated with Trichilemmal Cyst 1 is TRICY1 (Trichilemmal Cyst 1). Affiliated tissues include skin, and related phenotype is abnormality of the skin.

Related Diseases for Trichilemmal Cyst 1

Diseases related to Trichilemmal Cyst 1 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
# Related Disease Score Top Affiliating Genes
1 proliferating trichilemmal cyst 11.6
2 dowling-degos disease 11.2
3 perrault syndrome 1 11.1
4 nail disorder, nonsyndromic congenital, 3 9.9
5 steatocystoma multiplex 9.9
6 dermatofibrosarcoma protuberans 9.9
7 cholesteatoma of middle ear 9.9
8 flotch syndrome 9.9
9 friedel heid grosshans syndrome 9.9
10 leukonychia totalis 9.9
11 preauricular sinus 9.9

Graphical network of the top 20 diseases related to Trichilemmal Cyst 1:



Diseases related to Trichilemmal Cyst 1

Symptoms & Phenotypes for Trichilemmal Cyst 1

Symptoms via clinical synopsis from OMIM:

57
Skin Nails Hair Skin:
trichilemmal cysts
cyst occur most often on the scalp (89%)
cysts occur less commonly on any part of the body where hair grows
cysts may be solitary (30%)
cysts may be multiple (70%)
more
Skin Nails Hair Skin Histology:
cysts are lined by epidermal cells
cysts may contain degenerated keratin
cysts may become calcified


Clinical features from OMIM:

609649

Human phenotypes related to Trichilemmal Cyst 1:

32
# Description HPO Frequency HPO Source Accession
1 abnormality of the skin 32 HP:0000951

Drugs & Therapeutics for Trichilemmal Cyst 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Comparison of Excision Versus Punch Incision in the Treatment of Epidermal Cysts Completed NCT00165958 Phase 4

Search NIH Clinical Center for Trichilemmal Cyst 1

Genetic Tests for Trichilemmal Cyst 1

Anatomical Context for Trichilemmal Cyst 1

MalaCards organs/tissues related to Trichilemmal Cyst 1:

41
Skin

Publications for Trichilemmal Cyst 1

Articles related to Trichilemmal Cyst 1:

# Title Authors Year
1
Proliferating tricholemmal cyst should always be considered as a low-grade carcinoma. ( 9252767 )
1997
2
Proliferating tricholemmal cyst: a possible pitfall in cytological diagnosis. ( 8807257 )
1996

Variations for Trichilemmal Cyst 1

Expression for Trichilemmal Cyst 1

Search GEO for disease gene expression data for Trichilemmal Cyst 1.

Pathways for Trichilemmal Cyst 1

GO Terms for Trichilemmal Cyst 1

Sources for Trichilemmal Cyst 1

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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