MCID: TRC121
MIFTS: 23

Trichomonas Vaginalis Trichomoniasis

Categories: Infectious diseases, Reproductive diseases

Aliases & Classifications for Trichomonas Vaginalis Trichomoniasis

MalaCards integrated aliases for Trichomonas Vaginalis Trichomoniasis:

Name: Trichomonas Vaginalis Trichomoniasis 12
Trichomonas Vaginitis 43 17
Urogenital Trichomonas 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0050269
MeSH 43 D014247
NCIt 49 C35083
ICD10 32 A59.00

Summaries for Trichomonas Vaginalis Trichomoniasis

Disease Ontology : 12 A trichomoniasis that involves infection of the urogenital tract, has material basis in Trichomonas vaginalis, which is transmitted through sexual contact. Symptoms include inflammation of the cervix, urethra and vagina which produce an itching or burning sensation, and yellow-green, itchy, frothy foul-smelling vaginal discharge.

MalaCards based summary : Trichomonas Vaginalis Trichomoniasis, also known as trichomonas vaginitis, is related to vaginitis and trichomoniasis. The drugs Lidocaine and Tinidazole have been mentioned in the context of this disorder. Affiliated tissues include cervix, testes and breast.

Related Diseases for Trichomonas Vaginalis Trichomoniasis

Diseases related to Trichomonas Vaginalis Trichomoniasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)
# Related Disease Score Top Affiliating Genes
1 vaginitis 11.2
2 trichomoniasis 10.5
3 candidiasis 10.5
4 chlamydia 10.3
5 vulvovaginal candidiasis 10.2
6 bacterial vaginosis 10.2
7 bacterial infectious disease 10.0
8 fungal infectious disease 10.0
9 enthesopathy 10.0
10 cervix carcinoma 10.0
11 vaginal discharge 10.0
12 syphilis 10.0
13 reactive arthritis 10.0
14 candida glabrata 10.0

Graphical network of the top 20 diseases related to Trichomonas Vaginalis Trichomoniasis:



Diseases related to Trichomonas Vaginalis Trichomoniasis

Symptoms & Phenotypes for Trichomonas Vaginalis Trichomoniasis

Drugs & Therapeutics for Trichomonas Vaginalis Trichomoniasis

Drugs for Trichomonas Vaginalis Trichomoniasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
2
Tinidazole Approved, Investigational Phase 4 19387-91-8 5479
3
Metronidazole Approved Phase 3 443-48-1 4173
4
leucovorin Approved Phase 3 58-05-9 6006 143
5
Sulfadoxine Approved, Investigational Phase 3 2447-57-6 17134
6
Pyrimethamine Approved, Investigational, Vet_approved Phase 3 58-14-0 4993
7
Folic acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
8
Dihydroartemisinin Experimental, Investigational Phase 3 71939-50-9 6918483
9
Piperaquine Experimental, Investigational Phase 3 4085-31-8 5079497
10 Antiparasitic Agents Phase 3
11 Antiprotozoal Agents Phase 3
12 Anti-Bacterial Agents Phase 3
13 Anti-Infective Agents Phase 3
14 Vitamin B Complex Phase 3
15 Folic Acid Antagonists Phase 3
16 Fanasil, pyrimethamine drug combination Phase 3
17 Folate Phase 3
18 Vitamin B9 Phase 3
19 Antimalarials Phase 3
20
Clotrimazole Approved, Vet_approved 23593-75-1 2812
21
Miconazole Approved, Investigational, Vet_approved 22916-47-8 4189
22 Vaccines
23 Cytochrome P-450 Enzyme Inhibitors
24 Hormone Antagonists
25 Hormones
26 Antifungal Agents
27 Cytochrome P-450 CYP3A Inhibitors

Interventional clinical trials:

(show all 15)
# Name Status NCT ID Phase Drugs
1 A National, Multi-central, Open-label, Single-arm, Phase IV Study to Evaluate Efficacy and Safety of Gynomax® XL Ovule in the Treatment of Trichomonal Vaginitis, Bacterial Vaginosis, Candidal Vulvovaginitis and Mixed Vaginal Infections Completed NCT03839875 Phase 4 Gynomax® XL Vaginal Ovule
2 Intravaginal Treatment of Disturbances of Vaginal Flora Among HIV Infected and Uninfected Women in Malawi Completed NCT00140764 Phase 3 Metronidazole gel versus placebo gel
3 Trichomonas Vaginalis Repeat Infections Among HIV Negative Women Completed NCT01832480 Phase 3 MTZ 500 mg twice daily x 7 days;MTZ 2 g
4 Effects of Metronidazole Plus Intermittent Preventive Treatment of Malaria in Pregnancy on Birth Outcomes: a Randomised Controlled Trial in Zambia Recruiting NCT04189744 Phase 3 IPTp-sulphadoxine-pyrimethamine plus metronidazole;IPTp-dihydroartemisinin-piperaquine plus metronidazole;IPTp-sulphadoxine-pyrimethamine
5 Neo-Penotran Forte Vaginal Suppository for Vaginal Trichomoniasis Completed NCT01361048 Phase 2 oral metronidazole;neo penotran forte;neo penotran forte once a day
6 A Randomized, Placebo-controlled, Double-blind Trial to Assess Expanded Safety, Acceptability and Preliminary Effectiveness of PC-515 (Lambda Carrageenan) for Vaginal Use as a Possible Microbicide Completed NCT00213031 Phase 2 Carraguard (PC-515)
7 A Trial to Assess Expanded Safety, Acceptability and Preliminary Effectiveness of Carraguard™ (PC-515) in Preventing STI/HIV Transmission Completed NCT00213018 Phase 2 Carraguard (PC-515)
8 A Randomized, Placebo-controlled, Double-blind Trial to Assess Expanded Safety and Acceptability of Carraguard™ (PC-515) Vaginal Gel Among Heterosexual Couples in Chiang Rai Completed NCT00213057 Phase 1 Carraguard (PC-515)
9 Re-enrolling Young South African Mothers in School as a Social Vaccine Against HIV Transmission Unknown status NCT03090802
10 Non-Invasive Sexually Transmitted Disease Testing in Women Seeking Emergency Contraception or Urine Pregnancy Testing: Meeting the Needs of an At-Risk Population Completed NCT00978848
11 Trichomoniasis: Genotype and Phenotype Correlations in African American Women Completed NCT00998530
12 Observational Program Neo-Penotran® Forte Completed NCT01335373 Metronidazole/Miconazole (Neo-Penotran Forte, BAY86-5276)
13 DNA Clearance of Uncomplicated Trichomonas Vaginalis Infections in HIV Negative Women Completed NCT01874158
14 Evaluation of a Rapid Microscopic Diagnostic System for Different Vaginitis Conditions Not yet recruiting NCT04219605
15 Trichomonas Vaginalis Genotyping in Upper Egypt Not yet recruiting NCT03614286

Search NIH Clinical Center for Trichomonas Vaginalis Trichomoniasis

Cochrane evidence based reviews: trichomonas vaginitis

Genetic Tests for Trichomonas Vaginalis Trichomoniasis

Anatomical Context for Trichomonas Vaginalis Trichomoniasis

MalaCards organs/tissues related to Trichomonas Vaginalis Trichomoniasis:

40
Cervix, Testes, Breast

Publications for Trichomonas Vaginalis Trichomoniasis

Articles related to Trichomonas Vaginalis Trichomoniasis:

(show top 50) (show all 260)
# Title Authors PMID Year
1
Antiviral effect of Chinese herbal prescription JieZe-1 on adhesion and penetration of VK2/E6E7 with herpes simplex viruses type 2. 61
31743766 2020
2
Clinical Validation of the Aptima Bacterial Vaginosis and Aptima Candida/Trichomonas Vaginitis Assays: Results from a Prospective Multicenter Clinical Study. 61
31748322 2020
3
Evaluation of reliability of self-collected vaginal swabs over physician-collected samples for diagnosis of bacterial vaginosis, candidiasis and trichomoniasis, in a resource-limited setting: a cross-sectional study in India. 61
31462459 2019
4
Aerobic vaginitis in late pregnancy and outcomes of pregnancy. 61
30467614 2019
5
An evaluation study of the Becton-Dickinson ProbeTec Qx (BDQx) Trichomonas vaginalis trichomoniasis molecular diagnostic test in two large, urban STD services. 61
28108699 2018
6
Risk of high-risk human papillomavirus infection and cervical precancerous lesions with past or current trichomonas infection: a pooled analysis of 25,054 women in rural China. 61
29396352 2018
7
Vulvovaginite : Dépistage et prise en charge de la trichomonase, de la candidose vulvovaginale et de la vaginose bactérienne. 61
28063567 2016
8
Anti-Trichomonas vaginalis activity of betulinic acid derivatives. 61
27685791 2016
9
Sustained high prevalence of viral hepatitis and sexually transmissible infections among female sex workers in China: a systematic review and meta-analysis. 61
26732281 2016
10
Sexually transmitted infections in pediatric renal transplant recipients: Time to take notice! 61
26108149 2015
11
Metronidazole for the treatment of vaginal infections. 61
25887246 2015
12
Vulvovaginitis: screening for and management of trichomoniasis, vulvovaginal candidiasis, and bacterial vaginosis. 61
26001874 2015
13
Comparison of the Effect of Vaginal Zataria multiflora Cream and Oral Metronidazole Pill on Results of Treatments for Vaginal Infections including Trichomoniasis and Bacterial Vaginosis in Women of Reproductive Age. 61
26266260 2015
14
Oral tinidazole for refractory Trichomonas vaginitis. 61
24911187 2014
15
An association between Trichomonas vaginalis and high-risk human papillomavirus in rural Tanzanian women undergoing cervical cancer screening. 61
24417784 2014
16
Clinical characteristics of aerobic vaginitis and its association to vaginal candidiasis, trichomonas vaginitis and bacterial vaginosis. 61
25568514 2013
17
Correlation of leukorrhea and Trichomonas vaginalis infection. 61
23678058 2013
18
A cross-sectional study of gynaecological morbidity among married women in field practice area of community health centre Rajapur, Gulbarga. 61
24475557 2013
19
Lipid peroxidation and antioxidant status in vagina microenvironment of patients with several common vaginitis. 61
24283159 2013
20
Clinical and laboratory evidence of Trichomonas vaginalis infection among women of reproductive age in rural area. 61
22885198 2012
21
[One case of of trichomonas vaginitis complicated with gonorrhea]. 61
22908810 2012
22
Combined screening of cervical cancer, breast cancer and reproductive tract infections in rural China. 61
22994789 2012
23
A population-based study on the risks of cervical lesion and human papillomavirus infection among women in Beijing, People's Republic of China. 61
20719907 2010
24
[Analysis of high risk factors associated with cervical intraepithelial neoplasia in married women aged 25 - 54 years in Beijing between 2007 - 2008]. 61
21176557 2010
25
[Factors associated with abnormal cervical cytology in pregnant women]. 61
20420780 2010
26
Accuracy of vaginal symptom self-diagnosis algorithms for deployed military women. 61
20010039 2010
27
Sexually transmissible infections among female sex workers: an international review with an emphasis on hard-to-access populations. 61
18361849 2008
28
Prevalence of reproductive tract infections amongst ever married women and sociocultural factors associated with it. 61
17822170 2007
29
Study on the transmission of Toxoplasma gondii by semen in rabbits. 61
17094613 2006
30
Antibiotics for bacterial vaginosis or Trichomonas vaginalis in pregnancy: a systematic review. 61
15802417 2005
31
[Investigation on reproductive tract infection among floating married women of childbearing age in Fengtai district in Beijing]. 61
14521786 2003
32
Military women's risk factors for and symptoms of genitourinary infections during deployment. 61
12901470 2003
33
[Treatment of trichomonas vaginitis in pregnant women]. 61
12025703 2002
34
Over-the-counter antifungal drug misuse associated with patient-diagnosed vulvovaginal candidiasis. 61
11864668 2002
35
Reproductive health needs of young persons in markets and motor parks in south west Nigeria. 61
14510129 2001
36
The effect of treatment of vaginal infections on shedding of human immunodeficiency virus type 1. 61
11237825 2001
37
Determinants of incident vulvovaginal candidiasis in human immunodeficiency virus-positive women. 61
10968602 2000
38
Systematic review of diagnostic tests for vaginal trichomoniasis. 61
11220487 2000
39
Managing Resistant Trichomonas Vaginitis. 61
11095814 1999
40
Treatment of vaginal infections: candidiasis, bacterial vaginosis, and trichomoniasis. 61
9479409 1997
41
An incremental dosing protocol for women with severe vaginal trichomoniasis and adverse reaction to metronidazole. 61
8633672 1996
42
Trichomoniasis as seen in a chronic vaginitis clinic. 61
18476071 1996
43
Rapid antigen tests for Neisseria gonorrhoeae and Chlamydia trachomatis are not accurate for screening women with disturbed vaginal lactobacillary flora. 61
9060056 1996
44
The preterm prediction study: significance of vaginal infections. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. 61
7485327 1995
45
Bacterial vaginosis and HIV seroprevalence among female commercial sex workers in Chiang Mai, Thailand. 61
8527084 1995
46
Detection and identification of amines in bacterial vaginosis. 61
8591111 1995
47
Prevalence of vaginitis, syphilis and HIV infection in women in the Orange Free State. 61
7839281 1994
48
Is Trichomonas vaginalis a cause of cervical neoplasia? Results from a combined analysis of 24 studies. 61
8002180 1994
49
Vaginal infections: diagnosis and management. 61
8498288 1993
50
Vaginal PO2 in healthy women and in women infected with Trichomonas vaginalis: potential implications for metronidazole therapy. 61
1536244 1992

Variations for Trichomonas Vaginalis Trichomoniasis

Expression for Trichomonas Vaginalis Trichomoniasis

Search GEO for disease gene expression data for Trichomonas Vaginalis Trichomoniasis.

Pathways for Trichomonas Vaginalis Trichomoniasis

GO Terms for Trichomonas Vaginalis Trichomoniasis

Sources for Trichomonas Vaginalis Trichomoniasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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