MCID: TRC003
MIFTS: 53

Trichomoniasis

Categories: Infectious diseases, Nephrological diseases, Reproductive diseases

Aliases & Classifications for Trichomoniasis

MalaCards integrated aliases for Trichomoniasis:

Name: Trichomoniasis 12 74 54 42 3 15 32
Trichomonas Infections 43 71
Trichomonas Infection 12 3

Classifications:



External Ids:

Disease Ontology 12 DOID:1947
ICD9CM 34 131
MeSH 43 D014245
NCIt 49 C35720
SNOMED-CT 67 56335008
ICD10 32 A59 A59.9
UMLS 71 C0040921

Summaries for Trichomoniasis

MedlinePlus : 42 Trichomoniasis is a sexually transmitted disease caused by a parasite. It spreads from person to person during sex. Many people do not have any symptoms. If you do get symptoms, they usually happen within 5 to 28 days after being infected. It can cause vaginitis in women. Symptoms include Yellow-green or gray discharge from the vagina Discomfort during sex Vaginal odor Painful urination Itching burning, and soreness of the vagina and vulva Most men do not have symptoms. If they do, they may have Itching or irritation inside the penis Burning after urination or ejaculation Discharge from the penis Trichomoniasis can increase the risk of getting or spreading other sexually transmitted diseases. Pregnant women with trichomoniasis are more likely to give birth too early, and their babies are more likely have a low birth weight. Lab tests can tell if you have the infection. Treatment is with antibiotics. If you are infected, you and your partner must be treated. Correct usage of latex condoms greatly reduces, but does not eliminate, the risk of catching or spreading trichomoniasis. The most reliable way to avoid infection is to not have anal, vaginal, or oral sex. Centers for Disease Control and Prevention

MalaCards based summary : Trichomoniasis, also known as trichomonas infections, is related to pelvic inflammatory disease and oral candidiasis, and has symptoms including fever, pruritus and pelvic pain. An important gene associated with Trichomoniasis is IL2 (Interleukin 2), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Aztreonam and Acetylcysteine have been mentioned in the context of this disorder. Affiliated tissues include testes, cervix and prostate, and related phenotypes are hematopoietic system and immune system

Disease Ontology : 12 A parasitic protozoa infectious disease that is caused by singled-celled protozoan parasites Trichomonas vaginalis or Trichomonas tenax, which infect the urogenital tract and mouth respectively.

CDC : 3 Trichomoniasis (or "trich") is a very common sexually transmitted disease (STD). It is caused by infection with a protozoan parasite called Trichomonas vaginalis. Although symptoms of the disease vary, most people who have the parasite cannot tell they are infected.

Wikipedia : 74 Trichomoniasis (trich) is an infectious disease caused by the parasite Trichomonas vaginalis. About 70%... more...

Related Diseases for Trichomoniasis

Diseases related to Trichomoniasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 601)
# Related Disease Score Top Affiliating Genes
1 pelvic inflammatory disease 30.9 IL2 EPPIN CD40LG CD4
2 oral candidiasis 30.7 SLPI CXCL8 CD4
3 bacterial vaginosis 30.4 TNF LAP3 IL6 IL1B CXCL8
4 pyuria 30.4 IL6 CXCL8 CD40LG
5 genital herpes 30.4 CD40LG CD4 CCR5 ATAD2
6 chlamydia 30.2 TNF IL6 IL1B CXCL8 CD40LG
7 candidiasis 30.2 TNF IL6 IL2 IL1B CXCL8 CD40LG
8 vaginitis 30.0 TNF SLPI LAP3 IL6 IL1B EPPIN
9 syphilis 30.0 TNF IL6 CD40LG CD4 CCR5
10 placenta disease 30.0 TNF IL6 IL1B CXCL8
11 salpingitis 30.0 TNF CD40LG CD4
12 cystitis 30.0 TNF IL6 IL2 CXCL8
13 urethritis 29.9 TNF IL6 IL1B CXCL8 CD40LG CD4
14 prostatitis 29.9 TNF IL6 IL1B CXCL8
15 bronchiectasis 29.9 TNF SLPI IL1B CXCL8
16 amebiasis 29.8 TNF IL1B CXCL8 CD40LG CD4
17 filariasis 29.8 TNF IL6 IL2
18 esophagitis 29.7 TNF IL6 IL1B CXCL8
19 human immunodeficiency virus infectious disease 29.7 TNF SLPI IL2 CD4 CCR5 CCL20
20 endometritis 29.7 TNF IL6 IL1B CXCL8
21 schistosomiasis 29.7 TNF LGMN IL2 CD40LG
22 erythema multiforme 29.6 TNF IL6 IL2 CXCL8
23 human immunodeficiency virus type 1 29.5 TNF SLPI IL2 CD4 CCR5
24 toxoplasmosis 29.5 TNF IL6 IL1B CD40LG CCR5
25 immune deficiency disease 29.4 TNF IL6 IL2 CD40LG CD4 CCR5
26 acute cystitis 29.4 TNF IL6 IL1B CXCL8 CD40LG CD4
27 acute pancreatitis 29.4 TNF IL6 IL1B CXCL8
28 rhinitis 29.4 TNF IL6 IL1B CXCL8
29 lung abscess 29.4 TNF IL6 IL1B CD40LG CD4
30 diarrhea 29.3 TNF IL6 IL2 IL1B CXCL8 CD40LG
31 cervical cancer 29.3 TNF IL6 IL2 IL1B CXCL8 CD4
32 cervicitis 29.3 TNF IL6 IL2 IL1B CXCL8 CD4
33 trypanosomiasis 29.3 TNF IL6 IL2 IL1B CXCL8
34 vaginal discharge 29.3 TNF SLPI LAP3 IL6 IL1B CXCL8
35 chorioamnionitis 29.3 TNF SLPI IL6 IL1B CXCL8
36 sarcoidosis 1 29.0 TNF IL2 IL1B CD40LG CD4 CCR5
37 cystic fibrosis 28.9 TNF SLPI IL6 IL1B CXCL8 CD4
38 cellulitis 28.9 TNF IL6 IL2 IL1B CD40LG CD4
39 bacterial infectious disease 28.9 TNF IL6 IL1B CXCL8 CD40LG CD4
40 pharyngitis 28.9 TNF IL6 IL1B CXCL8 CD40LG CD4
41 fungal infectious disease 28.7 TNF IL6 IL2 IL1B CXCL8 CD40LG
42 stomatitis 28.7 TNF IL6 IL2 IL1B CXCL8 CD40LG
43 peripheral nervous system disease 28.7 TNF IL6 IL2 IL1B CXCL8 CD40LG
44 leishmaniasis 28.6 TNF LMLN IL6 IL2 IL1B CXCL8
45 parasitic protozoa infectious disease 28.3 TNF LMLN IL6 IL2 IL1B CXCL8
46 vaginal disease 28.1 TNF SLPI IL6 IL2 IL1B CXCL8
47 trichomonas vaginalis trichomoniasis 12.6
48 trichomonas tenax trichomoniasis 12.5
49 dientamoebiasis 11.8
50 infertility 10.5

Comorbidity relations with Trichomoniasis via Phenotypic Disease Network (PDN):


Acute Cystitis Hypertension, Essential

Graphical network of the top 20 diseases related to Trichomoniasis:



Diseases related to Trichomoniasis

Symptoms & Phenotypes for Trichomoniasis

UMLS symptoms related to Trichomoniasis:


fever, pruritus, pelvic pain

MGI Mouse Phenotypes related to Trichomoniasis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.7 CCR5 CD4 CD40LG IL1B IL2 IL6
2 immune system MP:0005387 9.36 CCR5 CD4 CD40LG IL1B IL2 IL6

Drugs & Therapeutics for Trichomoniasis

Drugs for Trichomoniasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 51)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aztreonam Approved Phase 4 78110-38-0 5742832 5362041
2
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
3
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
4
Ofloxacin Approved Phase 4 82419-36-1 4583
5
Tinidazole Approved, Investigational Phase 4 19387-91-8 5479
6
Clotrimazole Approved, Vet_approved Phase 4 23593-75-1 2812
7
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
8
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
9
Cysteine Approved, Nutraceutical Phase 4 52-90-4 5862
10 Respiratory System Agents Phase 4
11 Antidotes Phase 4
12 Expectorants Phase 4
13 Antioxidants Phase 4
14 Antiviral Agents Phase 4
15 N-monoacetylcystine Phase 4
16 Antibiotics, Antitubercular Phase 4
17 Protective Agents Phase 4
18 Alkylating Agents Phase 4
19 Cytochrome P-450 Enzyme Inhibitors Phase 4
20 Hormone Antagonists Phase 4
21 Hormones Phase 4
22 Anti-Infective Agents, Local Phase 4
23 Antifungal Agents Phase 4
24 Cytochrome P-450 CYP3A Inhibitors Phase 4
25 Clindamycin phosphate Phase 4
26 Clindamycin palmitate Phase 4
27
Secnidazole Approved Phase 3 3366-95-8
28
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
29
Metronidazole Approved Phase 3 443-48-1 4173
30
leucovorin Approved Phase 3 58-05-9 6006 143
31
Sulfadoxine Approved, Investigational Phase 3 2447-57-6 17134
32
Pyrimethamine Approved, Investigational, Vet_approved Phase 3 58-14-0 4993
33
Folic acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
34
Dihydroartemisinin Experimental, Investigational Phase 3 71939-50-9 6918483
35
Piperaquine Experimental, Investigational Phase 3 4085-31-8 5079497
36 Antiparasitic Agents Phase 3
37 Antiprotozoal Agents Phase 3
38 Anti-Infective Agents Phase 3
39 Anti-Bacterial Agents Phase 3
40 Vitamin B Complex Phase 3
41 Folic Acid Antagonists Phase 3
42 Fanasil, pyrimethamine drug combination Phase 3
43 Folate Phase 3
44 Vitamin B9 Phase 3
45 Antimalarials Phase 3
46
Titanium dioxide Approved Phase 2 13463-67-7
47 Pharmaceutical Solutions Phase 1
48
Terconazole Approved Early Phase 1 67915-31-5 441383
49
Ethanol Approved 64-17-5 702
50 Acidophilus

Interventional clinical trials:

(show top 50) (show all 52)
# Name Status NCT ID Phase Drugs
1 An Open-Lable Multicenter Prospective Non-Randomized Trial to Assess the Efficacy and Safety of Morinidazole With Surgery in Patients With Suppurative or Gangrenous Appendicitis Unknown status NCT03380793 Phase 4 morinidazole
2 Studying the Role of N-Acetyl Cysteine Either Alone or in Combination With Metronidazole in Treatment of Bacterial Vaginosis Unknown status NCT01841411 Phase 4 N-Acetyl cysteine;Metronidazole + N-Acetyl cysteine;metronidazole
3 An Open-Lable Multicenter Prospective Non-Randomized Trial to Assess the Efficacy and Safety of Morinidazole With Levofloxacin and Sequential of Levofloxacin in Women With Pelvic Inflammatory Disease Unknown status NCT03391440 Phase 4 morinidazole
4 Randomized Phase IV Trial of Metronidazole Single Dose Versus 7 Day Dose for Treatment of Trichomonas Vaginalis Among HIV-infected Women Completed NCT01018095 Phase 4 Metronidazole
5 Tinidazole for the Treatment of Bacterial Vaginosis Completed NCT00334633 Phase 4 tinidazole, metronidazole
6 A Comparative Open Labeled Clinical Study to Evaluate the Efficacy and Tolerability of Two Different Intravaginal Formulations Containing a Combination of Clindamycin and Clotrimazole in Vaginal Infections Completed NCT01697826 Phase 4 ClinSupV3 -soft gelatin capsule;ClinSupV3ER- Extended release tablet
7 A Phase 3, Multi-center, Prospective, Randomized, Placebo-Controlled, Delayed Treatment, Double-Blind Study to Evaluate the Effectiveness and Safety of a Single Oral Dose of Solosec® Granules Containing 2 Grams of Secnidazole for the Treatment of Trichomoniasis Completed NCT03935217 Phase 3 Secnidazole;Placebo
8 Trichomonas Vaginalis Repeat Infections Among HIV Negative Women Completed NCT01832480 Phase 3 MTZ 500 mg twice daily x 7 days;MTZ 2 g
9 A Randomised Controlled Trial of Single Dose Tinidazole+Fluconazole Versus Longer Courses of Metronidazole+Clotrimazole in the Management of West African Women With Vaginal Discharge Completed NCT00313131 Phase 3 tinidazole+fluconazole vs metronidazole+clotrimazole
10 Effects of Metronidazole Plus Intermittent Preventive Treatment of Malaria in Pregnancy on Birth Outcomes: a Randomised Controlled Trial in Zambia Recruiting NCT04189744 Phase 3 IPTp-sulphadoxine-pyrimethamine plus metronidazole;IPTp-dihydroartemisinin-piperaquine plus metronidazole;IPTp-sulphadoxine-pyrimethamine
11 Neo-Penotran Forte Vaginal Suppository for Vaginal Trichomoniasis Completed NCT01361048 Phase 2 oral metronidazole;neo penotran forte;neo penotran forte once a day
12 A Double-Blind, Randomized Trial of Monthly Treatment With Topical Metronidazole and Miconazole Co-formulated Vaginal Suppositories Versus Placebo for Preventing Vaginal Infections in HIV-seronegative Women Completed NCT01230814 Phase 2 Neo-Penotran® Forte (active ingredient Metronidazole & Miconazole Nitrate);Placebo
13 Prospective Study for Cost-Effectiveness Strategies to Improve Partner Notification: Female Trichomonas and Male Urethritis Studies Completed NCT00207467 Phase 2
14 HIV/STI Risk Reduction for Incarcerated Women With Interpersonal Violence Completed NCT01907126 Phase 2
15 A Brief, Clinic-Based, Safer Sex Program for Young African-American Men Completed NCT01439503 Phase 2
16 A Single Dose, Two-Period, Two-Treatment, Two-Way Crossover Bioequivalence Study of Tinidazole 500 mg Tablets Under Fed Conditions Completed NCT01591889 Phase 1 Tinidazole;Tinidazole
17 STARS: Sistas Talking About Real Solutions Completed NCT01028157 Phase 1
18 Rapid HIV Testing and Counseling in High Risk Women in Shelters Completed NCT01866046 Phase 1
19 "A Comparison Study of the WaterWorks® Douching Device vs. Commercial OTC Douching Device for the Reduction or Abatement of Perceived Vaginal Odor With or Without Complaints of Discharge in Women With no Infectious Causes of Vaginitis" Unknown status NCT00417365
20 Validation of a Novel Diagnostic, Prognostic Assay for Bacterial Vaginosis Unknown status NCT02185456 Early Phase 1 750 mg metronidazole/ 200 mg miconazole vaginal suppository;Standard of care
21 Relation Between Internal Vaginal Douching and Vaginal Infections in Intrauterine Contraceptive Device Users Unknown status NCT03261804
22 The Impact of Short-term Financial Incentives on Sexual Behavior and HIV Incidence Among Youth: Evidence From a Randomized Controlled Field Trial in Lesotho Unknown status NCT01589965 Early Phase 1
23 Control of Trichomoniasis - A Paradigm for STD Control Completed NCT00334555
24 "Solana™ Trichomonas Assay Field Study" Completed NCT02566447
25 Trichomoniasis: Genotype and Phenotype Correlations in African American Women Completed NCT00998530
26 Comparing NAAT Testing to Standard Methods in Diagnosis of Vaginal Infections in the General Gynecology and Vulvovaginal Referral Offices. Completed NCT02203942
27 Validity of Patient-Collected Wet Mounts Completed NCT02641717
28 Prospective Collection of Female First-catch Urine, Vaginal Swab, Endocervical Swab, and Cervical Specimens for Testing With the APTIMA Trichomonas Vaginalis Assay Completed NCT01427023
29 Non-Invasive Sexually Transmitted Disease Testing in Women Seeking Emergency Contraception or Urine Pregnancy Testing: Meeting the Needs of an At-Risk Population Completed NCT00978848
30 Clinical Evaluation of the Click Sexual Health Test for the Detection of Neisseria Gonorrhoeae (NG), Trichomonas Vaginalis (TV), and Chlamydia Trachomatis (CT) in Women Completed NCT04098900
31 A Validation Study of Genzyme Diagnostics OSOM Trichomonas Rapid Test and BVBlue Test Completed NCT00682851
32 DNA Clearance of Uncomplicated Trichomonas Vaginalis Infections in HIV Negative Women Completed NCT01874158
33 A Validation Study of the Cepheid Xpert CT/NG for Detecting Chlamydia Trachomatis and Neisseria Gonorrhoeae in Rectal Samples Completed NCT02099760
34 Observational Program Neo-Penotran® Forte Completed NCT01335373 Metronidazole/Miconazole (Neo-Penotran Forte, BAY86-5276)
35 Management of Vaginal Complaints: A Pilot Study Within a Practice-Based Research Network Completed NCT00503542 Early Phase 1 Terazol or oral fluconazole for candidal vaginitis;Metronidazole or Clindamycin for Bacterial Vaginosis;Flagyl for definitively diagnosed vaginal trichomoniasis
36 Sexually Transmitted Infections Among African American Women Who Have Sex With Women Completed NCT01546714
37 Prevalence Rates of Sexually Transmitted Infections and Sexual Risk Behaviors Among African American Women Who Have Sex With Women Completed NCT01043081
38 HIV Prevention Preparedness Study Completed NCT00048282
39 Pivotal Study of a Single-Use, Point-of-Care Molecular Diagnostic Device for the Detection of Neisseria Gonorrhoeae (NG), Trichomonas Vaginalis (TV), and Chlamydia Trachomatis (CT) in Women Completed NCT03852316
40 Adapting Project SAFE: Reducing STD/HIV Risk in Women Prisoners Completed NCT01111721
41 Four-Arm RCT of Brief MI vs. Couples-Based HIV/STI Prevention in South Africa Completed NCT01554423
42 A Case Control Study of Women With Multiple Sexual Partners Attending the Jefferson County Department of Health Sexually Transmitted Diseases Clinic Completed NCT01578915
43 Changing the STI Care Model to Reduce Genital Inflammation and HIV Risk in South African Women Completed NCT03407586
44 Use of Condoms in Prevention of Progression of Cervical Intraepithelial Neoplasia: A Randomized Controlled Trial. Completed NCT02907333
45 Evaluating a Microfinance Intervention for Vulnerable Women in Kazakhstan Completed NCT02406482
46 Repeat STI Patients: Tailored Socio-Contextual Intervention to Reduce HIV Risk Completed NCT01510262
47 Oral Probiotics to Reduce Vaginal Group B Streptococcal Colonization in Late Pregnancy: A Randomized Placebo-controlled Double-blinded Trial Completed NCT03008421
48 Impact and Process Evaluation of Integrated Community and Clinic-based HIV-1 Control: a Cluster-randomised Trial in Eastern Zimbabwe Completed NCT00390949
49 Trichomonas Vaginalis Genotyping in Upper Egypt Not yet recruiting NCT03614286
50 Prospective Collection of Female First-catch Urine, Vaginal Swab,Cervical, and Endocervical Swab Specimens for Testing With the APTIMA Assays Terminated NCT01728103

Search NIH Clinical Center for Trichomoniasis

Cochrane evidence based reviews: trichomonas infections

Genetic Tests for Trichomoniasis

Anatomical Context for Trichomoniasis

MalaCards organs/tissues related to Trichomoniasis:

40
Testes, Cervix, Prostate, Colon, Neutrophil, Skin, T Cells

Publications for Trichomoniasis

Articles related to Trichomoniasis:

(show top 50) (show all 3084)
# Title Authors PMID Year
1
Development of a convenient detection method for Trichomonas vaginalis based on loop-mediated isothermal amplification targeting adhesion protein 65. 61 42
32357839 2020
2
IL-6 produced by prostate epithelial cells stimulated with Trichomonas vaginalis promotes proliferation of prostate cancer cells by inducing M2 polarization of THP-1-derived macrophages. 42
32196489 2020
3
Protozoan genital invasions caused by the representatives of trichomonas and giardia. 42
32248179 2020
4
Comparison between secretory leukocytic protease inhibitor and reactive nitrogen intermediates levels in cervicovaginal secretions from symptomatic and asymptomatic trichomoniasis Egyptians patients. 54 61
17153694 2006
5
Cysteine proteases of Trichomonas vaginalis degrade secretory leukocyte protease inhibitor. 61 54
9728551 1998
6
Biochemical and structural characterisation of a protozoan beta-carbonic anhydrase from Trichomonas vaginalis. 61
32515610 2020
7
Actin Gene-Based Molecular Typing of Trichomonas vaginalis Clinical Isolates from the North of Iran. 61
32500506 2020
8
Proteomic signatures of metronidazole-resistant Trichomonas vaginalis reveal novel proteins associated with drug resistance. 61
32487244 2020
9
Trichomonas vaginalis NTPDase inhibited by lycorine modulates the parasite-neutrophil interaction. 61
32524267 2020
10
Data showing differential expression of Monocyte chemoattractant protein-1 in response to symptomatic and asymptomatic T. vaginalis infection. 61
32395589 2020
11
Ethnic variations in sexual partnerships and mixing, and their association with STI diagnosis: findings from a cross-sectional biobehavioural survey of attendees of sexual health clinics across England. 61
31422350 2020
12
The effect of iron on Trichomonas vaginalis TvCP2: a cysteine proteinase found in vaginal secretions of trichomoniasis patients. 61
32174285 2020
13
Developing a new drug against trichomoniasis, new inhibitory compounds of the protein triosephosphate isomerase. 61
32112829 2020
14
Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis among women with genitourinary infection and pregnancy-related complications in Tehran: A cross-sectional study. 61
32517577 2020
15
Early sex work initiation and its association with condomless sex and sexually transmitted infections among female sex workers in Iran. 61
32538329 2020
16
Trichomoniasis in a tertiary hospital of Madrid, Spain (2013-2017): prevalence and pregnancy rate, coinfections, metronidazole resistance, and endosymbiosis. 61
32405804 2020
17
Vaginal probiotic adherence and acceptability in Rwandan women with high sexual risk participating in a pilot randomised controlled trial: a mixed-methods approach. 61
32434932 2020
18
Gellan gum-based hydrogel containing nanocapsules for vaginal indole-3-carbinol delivery in trichomoniasis treatment. 61
32473199 2020
19
STI prevalence among women at risk for HIV exposure initiating safer conception care in rural, southwestern Uganda. 61
32404858 2020
20
Characterising HIV and STIs among transgender female sex workers: a longitudinal analysis. 61
32366602 2020
21
Trichomonas vaginalis in Pregnancy: Patterns and Predictors of Testing, Infection, and Treatment. 61
32282605 2020
22
Response to letter of comments: Comments on a retrospective epidemiological analysis of shared risk factors for bovine trichomoniasis and bovine genital campylobacteriosis in La Pampa province (Argentina). Highlighting a neglected agent: Leptospira sp. 61
31492445 2020
23
Call to action for health systems integration of point-of-care testing to mitigate the transmission and burden of sexually transmitted infections. 61
32241905 2020
24
HIV Testing Among Adolescents With Acute Sexually Transmitted Infections. 61
32179661 2020
25
Technologies, strategies and approaches for testing populations at risk of sexually transmitted infections: a systematic review protocol to inform prevention and control in EU/EEA countries. 61
32213195 2020
26
Diagnostic evaluation of the BD Affirm VPIII assay as a point-of-care test for the diagnosis of bacterial vaginosis, trichomoniasis and candidiasis. 61
32050856 2020
27
PCR Detection and Sequencing of Trichomonas vaginalis in Women with Suspected Vaginitis in the southwestern Iran. 61
32072909 2020
28
2'-Hydroxychalcones as an alternative treatment for trichomoniasis in association with metronidazole. 61
31853622 2020
29
Noncandidal vaginitis: a comprehensive approach to diagnosis and management. 61
31513780 2020
30
Multimodality Screening for Lower Genital Tract Infections Between 18 and 24 Weeks of Pregnancy and its Efficacy in Predicting Spontaneous Preterm Delivery. 61
32030004 2020
31
Antimicrobial resistance in sexually transmitted infections. 61
31840758 2020
32
Declining trends in HIV and other sexually transmitted infections among female sex workers in Iran could be attributable to reduced drug injection: a cross-sectional study. 61
31836679 2020
33
Antiparasitic activity of furanyl N-acylhydrazone derivatives against Trichomonas vaginalis: in vitro and in silico analyses. 61
32046788 2020
34
Impact of Symbiosis Between Trichomonas vaginalis and Mycoplasma hominis on Vaginal Dysbiosis: A Mini Review. 61
32457847 2020
35
Trichomonas Vaginalis Infection Among Women Attending Laboratory Centers in Ilam, Iran. 61
30652653 2020
36
Vaginal dysbiotic bacteria act as pathobionts of the protozoal pathogen Trichomonas vaginalis. 61
31669328 2020
37
Microbiota in vaginal health and pathogenesis of recurrent vulvovaginal infections: a critical review. 61
31992328 2020
38
Fortuitous diagnosis of Trichomoniasis by PCR using panfungal primers. 61
31726227 2020
39
Clinical Validation of the Aptima Bacterial Vaginosis and Aptima Candida/Trichomonas Vaginitis Assays: Results from a Prospective Multicenter Clinical Study. 61
31748322 2020
40
School suspension predicts trichomoniasis five years later in a matched sample. 61
31959144 2020
41
The association between region of birth and sexually transmitted infections among people of black Caribbean ethnicity attending sexual health services in England, 2015. 61
32084155 2020
42
Diagnostic performance of two molecular assays for the detection of vaginitis in symptomatic women. 61
31502121 2020
43
[Evaluation of Microscopic Examination, Culture and Polymerase Chain Reaction Tests in the Diagnosis of Trichomonas vaginalis Infection]. 61
32050884 2020
44
Is there association between Trichomonas vaginalis infection and prostate cancer risk?: A systematic review and meta-analysis. 61
31539586 2019
45
Efficacy of netropsin dihydrochloride against the viability, cytopathogenicity and hemolytic activity of Trichomonas vaginalis clinical isolates. 61
31189504 2019
46
Composite thermoresponsive hydrogel with auranofin-loaded nanoparticles for topical treatment of vaginal trichomonad infection. 61
32377561 2019
47
Prevalence of double-stranded RNA virus in Trichomonas vaginalis isolated in Italy and association with the symbiont Mycoplasma hominis. 61
31701295 2019
48
Major factors associated to persistence of bovine trichomoniasis in a mandatory control plan: A eight year retrospective study in La Pampa, Argentine. 61
31796194 2019
49
Reduced Trichomonas vaginalis viability in mice pretreated with parasite DNA. 61
31391128 2019
50
20S Proteasome as a Drug Target in Trichomonas vaginalis. 61
31451503 2019

Variations for Trichomoniasis

Expression for Trichomoniasis

Search GEO for disease gene expression data for Trichomoniasis.

Pathways for Trichomoniasis

Pathways related to Trichomoniasis according to GeneCards Suite gene sharing:

(show top 50) (show all 61)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.02 WASF3 TNF SLPI LGMN IRF6 IL6
2
Show member pathways
13.87 TNF IL6 IL2 IL1B CXCL8 CD40LG
3
Show member pathways
13.71 TNF IL6 IL2 IL1B CXCL8 CD40LG
4
Show member pathways
13.4 TNF IL6 IL2 IL1B CXCL8 CD40LG
5
Show member pathways
13.33 TNF IRF6 IL6 IL2 IL1B CXCL8
6
Show member pathways
13.24 TNF IL6 IL2 IL1B CXCL8 CD40LG
7
Show member pathways
13.09 TNF IL6 IL2 IL1B CXCL8 CCL4L1
8
Show member pathways
12.96 TNF IL6 IL1B CXCL8 CD4 CCR5
9
Show member pathways
12.86 TNF IL6 IL2 IL1B ENTPD8 CXCL8
10
Show member pathways
12.78 TNF LGMN IL6 IL2 IL1B CXCL8
11
Show member pathways
12.74 TNF IL6 IL2 IL1B CD40LG
12
Show member pathways
12.7 TNF IL1B CD40LG CD4 CCR5
13
Show member pathways
12.64 TNF IL6 IL2 IL1B CD4
14
Show member pathways
12.63 TNF IL6 IL2 IL1B CD4
15 12.61 TNF IRF6 IL2 IL1B CD40LG
16
Show member pathways
12.58 TNF IL6 IL2 IL1B CD40LG CD4
17
Show member pathways
12.38 TNF IL6 IL1B CXCL8 CCL20
18 12.37 TNF IL6 IL2 CD4
19
Show member pathways
12.36 TNF IL6 IL2 IL1B
20 12.35 WASF3 TNF IL6 IL1B CXCL8
21
Show member pathways
12.3 TNF IL1B CD40LG CCR5
22 12.3 WASF3 TNF IL6 IL1B CXCL8
23
Show member pathways
12.3 TNF IRF6 IL6 IL2 IL1B CXCL8
24 12.28 TNF IL6 IL1B CXCL8
25
Show member pathways
12.25 TNF IL6 IL2 IL1B
26 12.22 TNF IL6 IL1B CXCL8
27
Show member pathways
12.21 TNF IL6 IL1B CXCL8 CCL20
28
Show member pathways
12.2 TNF IL6 IL2 CXCL8 CCR5 CCL4L1
29 12.05 TNF IL6 IL2 CD4
30 12.05 TNF IL6 IL2 IL1B CXCL8
31 12.04 TNF IL6 IL1B CXCL8
32 12.02 TNF IL6 IL1B CCL20
33
Show member pathways
12.02 IL2 IL1B CD4 CCR5 CCL4L1
34 11.98 TNF IL6 IL1B CXCL8
35
Show member pathways
11.97 TNF IL6 IL2 IL1B CD4
36 11.96 TNF IL6 IL1B CXCL8
37 11.96 TNF IL6 IL1B CD4
38 11.95 TNF IL1B CXCL8 CD40LG CCL4L1
39 11.92 TNF LTB4R IL6 IL2 IL1B CXCL8
40 11.88 TNF IL6 IL1B CXCL8 CCL20
41 11.84 TNF IL2 IL1B CD4
42 11.82 IL6 IL2 CXCL8
43 11.81 TNF IL6 IL1B CXCL8
44
Show member pathways
11.81 TNF IL2 CXCL8 CD40LG
45 11.72 TNF IL6 IL2 IL1B CD4
46 11.71 TNF IL6 IL1B CXCL8
47 11.65 TNF IL6 IL1B CXCL8
48 11.6 TNF IL6 IL2
49 11.57 TNF IL2 IL1B
50 11.53 TNF IL6 IL1B

GO Terms for Trichomoniasis

Cellular components related to Trichomoniasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.65 TNF SLPI LGMN IL6 IL2 IL1B
2 extracellular space GO:0005615 9.32 TNF SLPI IL6 IL2 IL1B EPPIN

Biological processes related to Trichomoniasis according to GeneCards Suite gene sharing:

(show all 27)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 10.03 TNF IRF6 IL6 IL1B CD4 ATAD2
2 cell-cell signaling GO:0007267 9.93 IL2 IL1B CCR5 CCL20
3 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.91 TNF CD4 CCL4L1 CCL20
4 positive regulation of protein phosphorylation GO:0001934 9.89 TNF IL2 IL1B CD4
5 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.85 TNF IL6 IL1B CD40LG
6 cellular response to interleukin-1 GO:0071347 9.81 CXCL8 CCL4L1 CCL20
7 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.79 TNF IL6 IL2
8 cellular response to lipopolysaccharide GO:0071222 9.77 TNF IL6 IL1B CXCL8 CCR5
9 positive regulation of interleukin-6 production GO:0032755 9.76 TNF IL6 IL1B
10 cytokine-mediated signaling pathway GO:0019221 9.76 TNF IL6 IL2 IL1B CXCL8 CD4
11 neutrophil chemotaxis GO:0030593 9.73 IL1B CXCL8 CCL4L1 CCL20
12 positive regulation of interferon-gamma production GO:0032729 9.71 TNF IL2 IL1B
13 chemokine-mediated signaling pathway GO:0070098 9.71 CXCL8 CCR5 CCL4L1 CCL20
14 monocyte chemotaxis GO:0002548 9.7 IL6 CCL4L1 CCL20
15 negative regulation of neurogenesis GO:0050768 9.65 TNF IL6 IL1B
16 positive regulation of T cell proliferation GO:0042102 9.65 IL6 IL2 IL1B CD40LG CD4
17 positive regulation of glial cell proliferation GO:0060252 9.63 TNF IL6 IL1B
18 negative regulation of lipid storage GO:0010888 9.62 TNF IL6
19 regulation of establishment of endothelial barrier GO:1903140 9.61 TNF IL1B
20 inflammatory response GO:0006954 9.61 TNF LTB4R IL6 IL1B CXCL8 CD40LG
21 fusion of virus membrane with host plasma membrane GO:0019064 9.6 CD4 CCR5
22 regulation of immunoglobulin secretion GO:0051023 9.58 TNF CD40LG
23 positive regulation of fever generation GO:0031622 9.57 TNF IL1B
24 sequestering of triglyceride GO:0030730 9.51 TNF IL1B
25 positive regulation of neuroinflammatory response GO:0150078 9.5 TNF IL6 IL1B
26 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.49 TNF IL1B
27 immune response GO:0006955 9.36 TNF SLPI LTB4R IL6 IL2 IL1B

Molecular functions related to Trichomoniasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.17 TNF IL6 IL2 IL1B CXCL8 CD40LG
2 chemokine activity GO:0008009 9.13 CXCL8 CCL4L1 CCL20

Sources for Trichomoniasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
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48 NCI
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50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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