MCID: TRC006
MIFTS: 36

Trichosporonosis

Categories: Infectious diseases

Aliases & Classifications for Trichosporonosis

MalaCards integrated aliases for Trichosporonosis:

Name: Trichosporonosis 12 45 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:0050290
MeSH 45 D060586
UMLS 74 C0343939

Summaries for Trichosporonosis

Disease Ontology : 12 An opportunistic mycosis that results in disseminated infection, has material basis in Trichosporon and results in_formation_of nontender erythematous nodules anywhere on the body.

MalaCards based summary : Trichosporonosis is related to acquired immunodeficiency syndrome and chronic granulomatous disease. An important gene associated with Trichosporonosis is PTX3 (Pentraxin 3), and among its related pathways/superpathways are Cytokine Signaling in Immune system and T cell receptor signaling pathway. Affiliated tissues include bone, bone marrow and myeloid, and related phenotypes are behavior/neurological and hematopoietic system

Wikipedia : 77 Trichosporonosis is a systemic disease associated with fungi in the genus... more...

Related Diseases for Trichosporonosis

Diseases related to Trichosporonosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 116)
# Related Disease Score Top Affiliating Genes
1 acquired immunodeficiency syndrome 30.1 CSF2 IFNG TNF
2 chronic granulomatous disease 29.7 CSF2 CSF3 DECR1 IFNG
3 engraftment syndrome 10.4 CSF2 CSF3
4 felty syndrome 10.3 CSF2 CSF3
5 large granular lymphocyte leukemia 10.3 CSF2 IFNG
6 mucormycosis 10.3 CSF2 IFNG
7 candida glabrata 10.3 CSF2 IFNG
8 carotid artery thrombosis 10.3 CSF2 IFNG
9 human t-cell leukemia virus type 2 10.3 CSF2 IFNG
10 burns 10.3 CSF2 TNF
11 anemia of prematurity 10.3 CSF2 CSF3
12 staphylococcal toxic shock syndrome 10.3 IFNG TNF
13 autoimmune myocarditis 10.3 IFNG TNF
14 hemorrhagic fever 10.3 IFNG TNF
15 chronic beryllium disease 10.3 IFNG TNF
16 ecthyma 10.3 CSF2 CSF3
17 scleritis 10.3 IFNG TNF
18 miliary tuberculosis 10.3 IFNG TNF
19 chronic graft versus host disease 10.3 IFNG TNF
20 clonorchiasis 10.3 IFNG TNF
21 microscopic colitis 10.3 IFNG TNF
22 crohn's colitis 10.3 IFNG TNF
23 cryptococcal meningitis 10.3 CSF2 IFNG
24 central nervous system vasculitis 10.2 IFNG TNF
25 soft tissue sarcoma 10.2 IFNG TNF
26 tuberculous peritonitis 10.2 IFNG TNF
27 systemic onset juvenile idiopathic arthritis 10.2 IL18 TNF
28 intermediate uveitis 10.2 IFNG TNF
29 orofacial granulomatosis 10.2 IFNG TNF
30 primary systemic mycosis 10.2 IFNG TNF
31 posterior uveitis 10.2 IFNG TNF
32 poliomyelitis 10.2 IFNG TNF
33 eales disease 10.2 IFNG TNF
34 lichen disease 10.2 IFNG TNF
35 erythema multiforme 10.2 IFNG TNF
36 spotted fever 10.2 IFNG TNF
37 listeria meningitis 10.2 IL18 TNF
38 coccidiosis 10.2 IFNG TNF
39 hematopoietic stem cell transplantation 10.2 IFNG TNF
40 suppurative lymphadenitis 10.2 DECR1 IFNG
41 melanoma metastasis 10.2 IL18 TNF
42 aseptic meningitis 10.2 IFNG TNF
43 stachybotrys chartarum 10.2 IL18 TNF
44 ileitis 10.2 CSF2 TNF
45 inflammatory bowel disease 3 10.2 IL18 TNF
46 plasmodium vivax malaria 10.2 IFNG TNF
47 hypersensitivity reaction type iv disease 10.2 IFNG TNF
48 cyclic neutropenia 10.2 CSF2 CSF3 IFNG
49 leprosy 3 10.2 IFNG TNF
50 q fever 10.2 IFNG TNF

Graphical network of the top 20 diseases related to Trichosporonosis:



Diseases related to Trichosporonosis

Symptoms & Phenotypes for Trichosporonosis

MGI Mouse Phenotypes related to Trichosporonosis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.87 CA7 CBSL CSF2 DECR1 IFNG IL18
2 hematopoietic system MP:0005397 9.8 CBSL CSF2 CSF3 IFNG IL18 PTX3
3 immune system MP:0005387 9.7 CBSL CSF2 CSF3 IFNG IL18 PTX3
4 integument MP:0010771 9.43 CBSL CSF2 CSF3 IFNG IL18 TNF
5 respiratory system MP:0005388 9.02 CBSL CSF2 IFNG PTX3 TNF

Drugs & Therapeutics for Trichosporonosis

Search Clinical Trials , NIH Clinical Center for Trichosporonosis

Cochrane evidence based reviews: trichosporonosis

Genetic Tests for Trichosporonosis

Anatomical Context for Trichosporonosis

MalaCards organs/tissues related to Trichosporonosis:

42
Bone, Bone Marrow, Myeloid

Publications for Trichosporonosis

Articles related to Trichosporonosis:

(show top 50) (show all 73)
# Title Authors Year
1
Invasive trichosporonosis treated with voriconazole. ( 29693071 )
2018
2
Trichosporonosis ( 29494084 )
2018
3
Systemic trichosporonosis mimicking disseminated varicella zoster viral infection during blinatumomab therapy. ( 29032509 )
2018
4
Disseminated Trichosporonosis with Atypical Histology Findings in a Patient with Acute Lymphocytic Leukemia. ( 30468020 )
2018
5
In vivo pathogenicity of Trichosporon asahii isolates with different in vitro enzymatic profiles in an immunocompetent murine model of systemic trichosporonosis. ( 28992352 )
2017
6
Disseminated Cutaneous Trichosporonosis in an Adult Bone Marrow Transplant Patient. ( 28584756 )
2017
7
Trichosporonosis in Pediatric Patients With a Hematologic Disorder. ( 28510690 )
2017
8
Purpuric and cream-colored plaques in an immunocompromised person: A case of disseminated trichosporonosis. ( 27486593 )
2016
9
Recurrent trichosporonosis with central nervous system involvement in an allogeneic hematopoietic stem cell transplant recipient. ( 27425395 )
2016
10
Disseminated trichosporonosis due to Trichosporon asahii in a diabetic patient. ( 25885147 )
2015
11
Primary Cutaneous Trichosporonosis Responsive to Voriconazole. ( 26061448 )
2015
12
Invasive trichosporonosis in an AIDS patient: case report and review of the literature. ( 23970618 )
2014
13
Therapeutic efficacy of posaconazole in a murine model of disseminated trichosporonosis. ( 24252752 )
2013
14
Opportunistic yeast infections: candidiasis, cryptococcosis, trichosporonosis and geotrichosis. ( 23621330 )
2013
15
Development of a peptide nucleic acid probe to Trichosporon species and identification of trichosporonosis by use of in situ hybridization in formalin-fixed and paraffin-embedded (FFPE) sections. ( 23100341 )
2013
16
Breakthrough trichosporonosis in patients receiving echinocandins: case report and literature review. ( 22882952 )
2012
17
Primary cutaneous trichosporonosis caused by Trichosporon dermatis in an immunocompetent man. ( 21763573 )
2011
18
Current knowledge of Trichosporon spp. and Trichosporonosis. ( 21976604 )
2011
19
Fatal invasive trichosporonosis due to Trichosporon loubieri in a patient with T-lymphoblastic lymphoma. ( 20950223 )
2011
20
Probable invasive pulmonary trichosporonosis in a diabetic patient. ( 22003150 )
2011
21
Disseminated trichosporonosis in a burn patient: meningitis and cerebral abscess due to Trichosporon asahii. ( 22012010 )
2011
22
Differential diagnosis of trichosporonosis using conventional histopathological stains and electron microscopy. ( 20459537 )
2010
23
Invasive trichosporonosis caused by Trichosporon asahii and other unusual Trichosporon species at a medical center in Taiwan. ( 19489711 )
2009
24
Early detection of breakthrough trichosporonosis by serum PCR in a cord blood transplant recipient being prophylactically treated with voriconazole. ( 19131780 )
2008
25
Pathogenicity of Trichosporon asahii in a murine model of disseminated trichosporonosis. ( 19187595 )
2008
26
Quantitative PCR assay used to monitor serum Trichosporon asahii DNA concentrations in disseminated trichosporonosis. ( 18845986 )
2008
27
Real-time PCR assay to detect DNA in sera for the diagnosis of deep-seated trichosporonosis. ( 17579275 )
2007
28
Invasive trichosporonosis due to Trichosporon asahii in a non-immunocompromised host: a rare case report. ( 17377356 )
2007
29
Supplemental utility of nested PCR for the pathological diagnosis of disseminated trichosporonosis. ( 17786472 )
2007
30
The prophylactic effectiveness of various antifungal agents against the progression of trichosporonosis fungemia to disseminated disease in a neutropenic mouse model. ( 17189098 )
2007
31
Efficacy of voriconazole in a guinea pig model of invasive trichosporonosis. ( 16723595 )
2006
32
Breakthrough trichosporonosis in patients with acute myeloid leukemia receiving micafungin. ( 16840220 )
2006
33
Breakthrough trichosporonosis in patients with hematologic malignancies receiving micafungin. ( 16477548 )
2006
34
Efficacy of micafungin in combination with other drugs in a murine model of disseminated trichosporonosis. ( 15673724 )
2005
35
Trichosporon asahii as an emerging etiologic agent of disseminated trichosporonosis: a case report and an update. ( 17642680 )
2004
36
Trichosporonosis in a tertiary care cancer center: risk factors, changing spectrum and determinants of outcome. ( 15370667 )
2004
37
Disseminated trichosporonosis caused by Trichosporon loubieri. ( 14605194 )
2003
38
Vulvovaginal trichosporonosis. ( 14627220 )
2003
39
Disseminated trichosporonosis in a murine model of chronic granulomatous disease. ( 12868577 )
2003
40
[Pathogenesis of Trichosporon asahii and strategies for infectious control of disseminated trichosporonosis]. ( 12913806 )
2003
41
Disseminated trichosporonosis in China. ( 14641628 )
2003
42
Trichosporonosis, an unusual fungal infection in neonates. ( 11840086 )
2002
43
Trichosporonosis due to Trichosporon beigelli in two hospitalized patients. ( 12785180 )
2002
44
Breakthrough trichosporonosis in a bone marrow transplant recipient receiving caspofungin acetate. ( 12115115 )
2002
45
Identification of the first isolates of Trichosporon asahii var asahii from disseminated trichosporonosis in China. ( 12376026 )
2002
46
Deep-seated trichosporonosis in an immunocompetent patient: a case report of uterine trichosporonosis-correction. ( 12060890 )
2002
47
Trichosporonosis in a previously healthy child in Nepal. ( 11418736 )
2001
48
A nested PCR assay to detect DNA in sera for the diagnosis of deep-seated trichosporonosis. ( 11293480 )
2001
49
Deep-seated trichosporonosis in an immunocompetent patient: a case report of uterine trichosporonosis. ( 10987737 )
2000
50
Experimental model of progressive disseminated trichosporonosis in mice with latent trichosporonemia. ( 10970368 )
2000

Variations for Trichosporonosis

Expression for Trichosporonosis

Search GEO for disease gene expression data for Trichosporonosis.

Pathways for Trichosporonosis

Pathways related to Trichosporonosis according to GeneCards Suite gene sharing:

(show all 30)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.15 CSF2 CSF3 IFNG IL18 TNF
2
Show member pathways
12.23 CSF2 IFNG TNF
3
Show member pathways
12.14 CSF2 CSF3 IFNG TNF
4 12.05 IFNG IL18 TNF
5
Show member pathways
11.89 IFNG IL18 TNF
6
Show member pathways
11.87 CSF2 IFNG TNF
7 11.77 CSF2 CSF3 IFNG TNF
8 11.75 CSF2 CSF3 TNF
9 11.73 CSF2 IFNG TNF
10 11.68 CSF2 IFNG IL18
11 11.64 IFNG IL18 TNF
12 11.63 CSF2 IFNG IL18 TNF
13
Show member pathways
11.6 CSF2 IFNG TNF
14 11.58 CSF2 IFNG TNF
15
Show member pathways
11.5 CSF2 IFNG TNF
16 11.47 CSF2 IFNG IL18 TNF
17 11.36 CSF2 CSF3 PTX3 TNF
18 11.35 IFNG IL18 TNF
19 11.29 ICAM3 IFNG
20 11.2 IFNG IL18 TNF
21 11.15 CSF2 CSF3 IL18 TNF
22 11.11 IFNG IL18 TNF
23 11.08 IFNG IL18
24 11.03 IFNG IL18
25 11.01 CSF2 CSF3 IL18 TNF
26 10.95 IL18 TNF
27 10.95 CSF3 IFNG IL18 TNF
28 10.91 IFNG IL18
29 10.83 CSF2 CSF3 IL18 TNF
30 10.39 CSF2 CSF3 IFNG TNF

GO Terms for Trichosporonosis

Cellular components related to Trichosporonosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.43 CSF2 CSF3 IFNG IL18 PTX3 TNF
2 extracellular space GO:0005615 9.1 CSF2 CSF3 IFNG IL18 PTX3 TNF

Biological processes related to Trichosporonosis according to GeneCards Suite gene sharing:

(show all 24)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.81 CSF2 IFNG IL18 TNF
2 cytokine-mediated signaling pathway GO:0019221 9.78 CSF2 CSF3 IL18 TNF
3 MAPK cascade GO:0000165 9.77 CSF2 IL18 TNF
4 extracellular matrix organization GO:0030198 9.77 ICAM3 PTX3 TNF
5 positive regulation of protein kinase B signaling GO:0051897 9.74 CSF3 IL18 TNF
6 cellular response to lipopolysaccharide GO:0071222 9.73 CSF2 CSF3 TNF
7 immune response GO:0006955 9.72 CSF2 CSF3 IFNG IL18 TNF
8 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.63 CSF3 IL18 TNF
9 positive regulation of phagocytosis GO:0050766 9.62 PTX3 TNF
10 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.61 CSF2 TNF
11 lipopolysaccharide-mediated signaling pathway GO:0031663 9.61 IL18 TNF
12 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.61 CSF2 IFNG IL18
13 negative regulation of myoblast differentiation GO:0045662 9.58 IL18 TNF
14 positive regulation of protein complex assembly GO:0031334 9.58 IFNG TNF
15 positive regulation of osteoclast differentiation GO:0045672 9.55 IFNG TNF
16 positive regulation of macrophage derived foam cell differentiation GO:0010744 9.54 CSF2 IL18
17 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.52 IFNG TNF
18 positive regulation of podosome assembly GO:0071803 9.49 CSF2 TNF
19 positive regulation of neuroinflammatory response GO:0150078 9.4 IL18 TNF
20 positive regulation of interleukin-23 production GO:0032747 9.37 CSF2 IFNG
21 regulation of signaling receptor activity GO:0010469 9.35 CSF2 CSF3 IFNG IL18 TNF
22 positive regulation of nitric oxide biosynthetic process GO:0045429 9.33 IFNG PTX3 TNF
23 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.26 IFNG TNF
24 positive regulation of vitamin D biosynthetic process GO:0060557 8.62 IFNG TNF

Molecular functions related to Trichosporonosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 CSF2 CSF3 IFNG IL18 TNF

Sources for Trichosporonosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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