MCID: TRG001
MIFTS: 30

Trigonitis

Categories: Nephrological diseases

Aliases & Classifications for Trigonitis

MalaCards integrated aliases for Trigonitis:

Name: Trigonitis 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:13507
ICD10 33 N30.3
ICD9CM 35 595.3
NCIt 50 C123175
SNOMED-CT 68 74445007
UMLS 73 C1261278

Summaries for Trigonitis

MalaCards based summary : Trigonitis is related to leiomyoma and meningioma, familial. An important gene associated with Trigonitis is PGR (Progesterone Receptor), and among its related pathways/superpathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Signaling by ERBB4. Affiliated tissues include bone, lung and ovary, and related phenotypes are hematopoietic system and integument

Wikipedia : 76 Trigonitis is a condition of inflammation of the trigone region of the bladder. It is more common in... more...

Related Diseases for Trigonitis

Diseases related to Trigonitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 135)
# Related Disease Score Top Affiliating Genes
1 leiomyoma 29.9 CD34 ESR1 PGR
2 meningioma, familial 29.6 CD34 ESR1 PGR
3 bladder trigone cancer 12.3
4 interstitial cystitis 11.6
5 vesicoureteral reflux 1 10.1
6 leiomyomatosis 10.1 ESR1 PGR
7 myoma 10.1 ESR1 PGR
8 vestibular gland benign neoplasm 10.1 ESR1 PGR
9 prostate stromal sarcoma 10.1 CD34 PGR
10 bartholin's gland adenoma 10.1 ESR1 PGR
11 vulvar syringoma 10.1 ESR1 PGR
12 glassy cell carcinoma of the cervix 10.1 ESR1 PGR
13 lung leiomyoma 10.1 ESR1 PGR
14 vulvar benign neoplasm 10.1 ESR1 PGR
15 vulvar leiomyoma 10.1 ESR1 PGR
16 lung meningioma 10.1 CD34 PGR
17 predominantly cortical thymoma 10.1 ESR1 PGR
18 vulvar dystrophy 10.1 CD34 PGR
19 breast medullary carcinoma 10.1 ESR1 PGR
20 breast scirrhous carcinoma 10.1 ESR1 PGR
21 bartholin's gland benign neoplasm 10.1 ESR1 PGR
22 oncocytic breast carcinoma 10.1 ESR1 PGR
23 progesterone-receptor positive breast cancer 10.1 ESR1 PGR
24 progesterone resistance 10.1 ESR1 PGR
25 endometrial squamous cell carcinoma 10.1 ESR1 PGR
26 cribriform carcinoma 10.1 ESR1 PGR
27 endometrial mucinous adenocarcinoma 10.1 ESR1 PGR
28 adenoid basal cell carcinoma 10.1 ESR1 PGR
29 breast adenoid cystic carcinoma 10.1 ESR1 PGR
30 apocrine adenocarcinoma 10.1 ESR1 PGR
31 gender identity disorder 10.1 ESR1 PGR
32 synchronous bilateral breast carcinoma 10.1 ESR1 PGR
33 female reproductive endometrioid cancer 10.1 ESR1 PGR
34 cervical carcinosarcoma 10.1 ESR1 PGR
35 estrogen excess 10.1 ESR1 PGR
36 glycogen-rich clear cell breast carcinoma 10.1 ESR1 PGR
37 mammographic density 10.1 ESR1 PGR
38 cervical clear cell adenocarcinoma 10.1 ESR1 PGR
39 retinitis pigmentosa 47 10.1 ESR1 PGR
40 inflammatory breast carcinoma 10.1 ESR1 PGR
41 retinitis pigmentosa 20 10.1 ESR1 PGR
42 adenosarcoma 10.1 ESR1 PGR
43 luminal breast carcinoma 10.1 ESR1 PGR
44 endometriosis of ovary 10.1 ESR1 PGR
45 endometriosis 10.1 ESR1 PGR
46 breast myofibroblastoma 10.1 CD34 ESR1
47 uterine corpus cancer 10.1 ESR1 PGR
48 lipid-rich carcinoma 10.1 ESR1 PGR
49 smooth muscle tumor 10.1 ESR1 PGR
50 glomangiomyoma 10.1 CD34 ESR1

Comorbidity relations with Trigonitis via Phenotypic Disease Network (PDN):


Acute Cystitis Female Stress Incontinence
Hypertension, Essential Urethral Stricture
Urethritis

Graphical network of the top 20 diseases related to Trigonitis:



Diseases related to Trigonitis

Symptoms & Phenotypes for Trigonitis

MGI Mouse Phenotypes related to Trigonitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.35 AFM CD34 CSF3 ESR1 PGR
2 integument MP:0010771 8.92 CD34 CSF3 ESR1 PGR

Drugs & Therapeutics for Trigonitis

Search Clinical Trials , NIH Clinical Center for Trigonitis

Genetic Tests for Trigonitis

Anatomical Context for Trigonitis

MalaCards organs/tissues related to Trigonitis:

41
Bone, Lung, Ovary, Prostate, Cervix, Smooth Muscle, Bone Marrow

Publications for Trigonitis

Articles related to Trigonitis:

(show all 15)
# Title Authors Year
1
Pseudomembranous trigonitis in a male with Klinefelter syndrome: a case report and evidence of a hormonal etiology. ( 25031763 )
2014
2
Immunohistochemical detection of estrogen and progesterone receptors in the normal urinary bladder and in pseudomembranous trigonitis. ( 1491120 )
1992
3
The fine structure of human pseudomembranous trigonitis. ( 2611616 )
1989
4
Pseudomembranous trigonitis of the bladder: hormonal aetiology. ( 2794080 )
1989
5
Histological findings in pseudomembranous trigonitis. ( 5118826 )
1971
6
Pseudomembranoous trigonitis. ( 5420763 )
1970
7
Trigonitis during pregnancy. A method of treatment. ( 13746217 )
1961
8
Frequency in the female due to urethro-trigonitis caused by intestinal infection. ( 13356048 )
1956
9
Segmental nerve lesions as a cause of the trigonitis syndrome. ( 13056835 )
1953
10
Chronic urethro-trigonitis in the female. ( 15417310 )
1950
11
The aetiology and treatment of trigonitis in the female. ( 18100624 )
1948
12
Clinical report of the frequent association of trigonitis with chronic cervicitis and vaginitis; diagnosis and treatment. ( 20290774 )
1947
13
Epithelium of vaginal type in the female trigone; the clinical problem of trigonitis. ( 20243913 )
1947
14
Urethro-trigonitis in relation to abacterial pyuria. ( 20284829 )
1946
15
OBSCURE PSEUDOMEMBRANOUS TRIGONITIS: TRIGONITIS AREATA ALBA. ( 17856488 )
1935

Variations for Trigonitis

Expression for Trigonitis

Search GEO for disease gene expression data for Trigonitis.

Pathways for Trigonitis

Pathways related to Trigonitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.32 CD34 CSF3
2
Show member pathways
11.19 ESR1 PGR
3 10.94 CD34 CSF3
4
Show member pathways
10.58 ESR1 PGR

GO Terms for Trigonitis

Biological processes related to Trigonitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of DNA-binding transcription factor activity GO:0051091 9.32 CSF3 ESR1
2 negative regulation of neuron death GO:1901215 9.26 CD34 CSF3
3 steroid hormone mediated signaling pathway GO:0043401 9.16 ESR1 PGR
4 negative regulation of gene expression GO:0010629 9.13 CD34 ESR1 PGR
5 paracrine signaling GO:0038001 8.62 CD34 PGR

Molecular functions related to Trigonitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ATPase binding GO:0051117 9.32 ESR1 PGR
2 steroid hormone receptor activity GO:0003707 9.26 ESR1 PGR
3 nuclear receptor activity GO:0004879 9.16 ESR1 PGR
4 enzyme binding GO:0019899 9.13 CSF3 ESR1 PGR
5 steroid binding GO:0005496 8.62 ESR1 PGR

Sources for Trigonitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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