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MCID: TRP009
MIFTS: 39
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Triple X Syndrome
Categories:
Rare diseases, Reproductive diseases, Endocrine diseases, Fetal diseases
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MalaCards integrated aliases for Triple X Syndrome:
Characteristics:Orphanet epidemiological data:59
trisomy x
Inheritance: Not applicable; Age of onset: Childhood,Infancy; Age of death: normal life expectancy; Classifications:
MalaCards categories:
Global: Rare diseases Fetal diseases Anatomical: Reproductive diseases Endocrine diseases
ICD10:
34
Orphanet: 59
Rare infertility disorders
Rare gynaecological and obstetric diseases
Rare endocrine diseases
Developmental anomalies during embryogenesis
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NIH Rare Diseases
:
53
47 XXX syndrome, also called trisomy X or triple X syndrome, is characterized by the presence of an additional (third) X chromosome in each of a female's cells (which normally have two X chromosomes). An extra copy of the X chromosome is associated with tall stature, learning problems, and other features in some girls and women. Seizures or kidney abnormalities occur in about 10 percent of affected females. 47 XXX syndrome is usually caused by a random event during the formation of reproductive cells (eggs and sperm). An error in cell division called nondisjunction can result in reproductive cells with an abnormal number of chromosomes. Treatment typically focuses on specific symptoms, if present. Some females with 47 XXX syndrome have an extra X chromosome in only some of their cells; this is called 46,XX/47,XXX mosaicism.
MalaCards based summary : Triple X Syndrome, also known as xxx syndrome, is related to numeric sex chromosome variations and chromosome xq duplication. An important gene associated with Triple X Syndrome is SHOX (Short Stature Homeobox). The drugs Testosterone and Epinephrine have been mentioned in the context of this disorder. Affiliated tissues include kidney, brain and hypothalamus, and related phenotypes are multicystic kidney dysplasia and tall stature Genetics Home Reference : 25 Triple X syndrome, also called trisomy X or 47,XXX, is characterized by the presence of an additional X chromosome in each of a female's cells. Although females with this condition may be taller than average, this chromosomal change typically causes no unusual physical features. Most females with triple X syndrome have normal sexual development and are able to conceive children. Wikipedia : 76 Triple X syndrome, also known as trisomy X and 47,XXX, is characterized by the presence of an extra X... more... |
Human phenotypes related to Triple X Syndrome:59 32 (show all 21)
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Drugs for Triple X Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):
Interventional clinical trials:
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Genetic tests related to Triple X Syndrome:
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MalaCards organs/tissues related to Triple X Syndrome:41
Kidney,
Brain,
Hypothalamus,
T Cells,
Thyroid,
Bone,
Ovary
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Articles related to Triple X Syndrome:(show all 36)
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Genes related to Triple X Syndrome (0 elite genes):
- Elite gene
- Cancer Census gene in COSMIC
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Search
GEO
for disease gene expression data for Triple X Syndrome.
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