MCID: TRP009
MIFTS: 42

Triple X Syndrome

Categories: Endocrine diseases, Fetal diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Triple X Syndrome

MalaCards integrated aliases for Triple X Syndrome:

Name: Triple X Syndrome 74 52 25 58
Xxx Syndrome 52 25 58
Trisomy X 52 25 58
Trisomy X Syndrome 29 71
Triplo X Syndrome 52 25
47,xxx Syndrome 25 58
47,xxx 74 25
Triple-X Chromosome Syndrome 52
Triplo-X Syndrome 58
47 Xxx Syndrome 52
Triple-X Female 52

Characteristics:

Orphanet epidemiological data:

58
trisomy x
Inheritance: Not applicable; Age of onset: Childhood,Infancy; Age of death: normal life expectancy;

Classifications:

Orphanet: 58  
Rare infertility disorders
Rare gynaecological and obstetric diseases
Rare endocrine diseases
Developmental anomalies during embryogenesis


External Ids:

MESH via Orphanet 44 D014314
ICD10 via Orphanet 33 Q97.0
UMLS via Orphanet 72 C0221033
Orphanet 58 ORPHA3375
UMLS 71 C0221033

Summaries for Triple X Syndrome

NIH Rare Diseases : 52 47 XXX syndrome , also called trisomy X or triple X syndrome, is characterized by the presence of an additional (third) X chromosome in each of a female's cells (which normally have two X chromosomes ). An extra copy of the X chromosome is associated with tall stature, learning problems, and other features in some girls and women. Seizures or kidney abnormalities occur in about 10 percent of affected females. 47 XXX syndrome is usually caused by a random event during the formation of reproductive cells (eggs and sperm). An error in cell division called nondisjunction can result in reproductive cells with an abnormal number of chromosomes. Treatment typically focuses on specific symptoms, if present. Some females with 47 XXX syndrome have an extra X chromosome in only some of their cells; this is called 46,XX/47,XXX mosaicism .

MalaCards based summary : Triple X Syndrome, also known as xxx syndrome, is related to numeric sex chromosome variations and chromosome xq duplication. An important gene associated with Triple X Syndrome is SHOX (Short Stature Homeobox). The drugs Metformin and Entecavir have been mentioned in the context of this disorder. Affiliated tissues include breast, lung and kidney, and related phenotypes are abnormality of chromosome segregation and muscular hypotonia

Genetics Home Reference : 25 Triple X syndrome, also called trisomy X or 47,XXX, is characterized by the presence of an additional X chromosome in each of a female's cells. Although females with this condition may be taller than average, this chromosomal change typically causes no unusual physical features. Most females with triple X syndrome have normal sexual development and are able to conceive children. Triple X syndrome is associated with an increased risk of learning disabilities and delayed development of speech and language skills. Delayed development of motor skills (such as sitting and walking), weak muscle tone (hypotonia), and behavioral and emotional difficulties are also possible, but these characteristics vary widely among affected girls and women. Seizures or kidney abnormalities occur in about 10 percent of affected females.

Wikipedia : 74 Triple X syndrome, also known as trisomy X and 47,XXX, is characterized by the presence of an extra X... more...

Related Diseases for Triple X Syndrome

Graphical network of the top 20 diseases related to Triple X Syndrome:



Diseases related to Triple X Syndrome

Symptoms & Phenotypes for Triple X Syndrome

Human phenotypes related to Triple X Syndrome:

58 31 (show all 21)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 abnormality of chromosome segregation 58 31 hallmark (90%) Very frequent (99-80%) HP:0002916
2 muscular hypotonia 58 31 frequent (33%) Frequent (79-30%) HP:0001252
3 global developmental delay 58 31 frequent (33%) Frequent (79-30%) HP:0001263
4 cognitive impairment 58 31 frequent (33%) Frequent (79-30%) HP:0100543
5 epicanthus 58 31 frequent (33%) Frequent (79-30%) HP:0000286
6 specific learning disability 58 31 frequent (33%) Frequent (79-30%) HP:0001328
7 clinodactyly of the 5th finger 58 31 frequent (33%) Frequent (79-30%) HP:0004209
8 tall stature 58 31 frequent (33%) Frequent (79-30%) HP:0000098
9 hypertelorism 58 31 occasional (7.5%) Occasional (29-5%) HP:0000316
10 pectus excavatum 58 31 occasional (7.5%) Occasional (29-5%) HP:0000767
11 seizures 58 31 occasional (7.5%) Occasional (29-5%) HP:0001250
12 depressivity 58 31 occasional (7.5%) Occasional (29-5%) HP:0000716
13 tremor 58 31 occasional (7.5%) Occasional (29-5%) HP:0001337
14 hip dysplasia 58 31 occasional (7.5%) Occasional (29-5%) HP:0001385
15 joint hyperflexibility 58 31 occasional (7.5%) Occasional (29-5%) HP:0005692
16 attention deficit hyperactivity disorder 58 31 occasional (7.5%) Occasional (29-5%) HP:0007018
17 anxiety 58 31 occasional (7.5%) Occasional (29-5%) HP:0000739
18 secondary amenorrhea 58 31 occasional (7.5%) Occasional (29-5%) HP:0000869
19 renal hypoplasia/aplasia 58 31 occasional (7.5%) Occasional (29-5%) HP:0008678
20 upslanted palpebral fissure 58 31 occasional (7.5%) Occasional (29-5%) HP:0000582
21 multicystic kidney dysplasia 58 31 occasional (7.5%) Occasional (29-5%) HP:0000003

Drugs & Therapeutics for Triple X Syndrome

Drugs for Triple X Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 818)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Metformin Approved Phase 4 657-24-9 14219 4091
2
Entecavir Approved, Investigational Phase 4 142217-69-4 153941
3
Pioglitazone Approved, Investigational Phase 4 111025-46-8 4829
4
Bivalirudin Approved, Investigational Phase 4 128270-60-0 16129704
5
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
6
Ertapenem Approved, Investigational Phase 4 153832-46-3 150610
7
Tranexamic Acid Approved Phase 4 1197-18-8 5526
8
Mepivacaine Approved, Vet_approved Phase 4 96-88-8 4062
9
Tetracaine Approved, Vet_approved Phase 4 94-24-6 5411
10
Glyburide Approved Phase 4 10238-21-8 3488
11
Glimepiride Approved Phase 4 93479-97-1 3476
12
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
13
Racepinephrine Approved Phase 4 329-65-7 838
14
Ethanol Approved Phase 4 64-17-5 702
15
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
16
Ciclesonide Approved, Investigational Phase 4 126544-47-6, 141845-82-1 444033
17
Histamine Approved, Investigational Phase 4 51-45-6 774
18
Insulin glargine Approved Phase 4 160337-95-1
19
Tinidazole Approved, Investigational Phase 4 19387-91-8 5479
20
Rabeprazole Approved, Investigational Phase 4 117976-89-3 5029
21
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
22
Modafinil Approved, Investigational Phase 4 68693-11-8 4236
23
Lixisenatide Approved Phase 4 320367-13-3
24
Haloperidol Approved Phase 4 52-86-8 3559
25
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
26
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
27
Methylphenidate Approved, Investigational Phase 4 113-45-1 4158
28
Abciximab Approved Phase 4 143653-53-6
29
Morphine Approved, Investigational Phase 4 57-27-2 5288826
30
Ribavirin Approved Phase 4 36791-04-5 37542
31
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
32
Nystatin Approved, Vet_approved Phase 4 1400-61-9 11953884
33
Efavirenz Approved, Investigational Phase 4 154598-52-4 64139
34
Peginterferon alfa-2a Approved, Investigational Phase 4 198153-51-4 5360545
35
Remifentanil Approved Phase 4 132875-61-7 60815
36
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
37
Oxymetazoline Approved, Investigational Phase 4 1491-59-4 4636
38
Phenylephrine Approved Phase 4 59-42-7 6041
39
Atropine Approved, Vet_approved Phase 4 5908-99-6, 51-55-8 174174
40
Adenosine Approved, Investigational Phase 4 58-61-7 60961
41
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
42
Norepinephrine Approved Phase 4 51-41-2 439260
43
Pseudoephedrine Approved Phase 4 90-82-4 7028
44
Ephedrine Approved Phase 4 299-42-3 9294
45
Ondansetron Approved Phase 4 99614-02-5 4595
46
Loratadine Approved, Investigational Phase 4 79794-75-5 3957
47
Latanoprost Approved, Investigational Phase 4 130209-82-4 5282380 5311221
48
Timolol Approved Phase 4 26839-75-8 33624 5478
49
Dorzolamide Approved Phase 4 120279-96-1 3154 5284549
50
Bimatoprost Approved, Investigational Phase 4 155206-00-1 5311027

Interventional clinical trials:

(show top 50) (show all 1063)
# Name Status NCT ID Phase Drugs
1 Clinical Trial Program of a Medical Instrument Product Unknown status NCT01157455 Phase 4 Aspirin;Clopidogrel;Heparin or Bivalirudin
2 Randomized Phase IV Trial to Compare Cetuximab With Concomitant Radiation Therapy With Concomitant Mitomycin-C and 5-Fluorouracil With Radiation Therapy for Locally Advanced Squamous Cell Carcinomas of the Head and Neck Unknown status NCT02015650 Phase 4 Cetuximab;Mitomycin-C/ 5-Fluorouracil
3 Phase IV Study of the Efficacy of Entecavir in Patients With Chronic Hepatitis B Virus Infection and Persistently Normal Alanine Aminotransferase Unknown status NCT01833611 Phase 4 Entecavir;placebo
4 Cross-reactivity and Tolerability of Ertapenem in Patients With IgE-mediated Allergy to Beta-lactams Unknown status NCT01159379 Phase 4 ertapenem
5 Minimization of Bleeding Complications Through Utilization of Perioperative Tranexamic Acid in Breast Surgery: A Randomized Double-blinded Placebo-controlled Trial Unknown status NCT02615366 Phase 4 Tranexamic Acid;Placebo
6 Pulpal Blood Flow With the Use of Intra-nasal Anesthetic: a Randomized Double-blind Crossover Study Unknown status NCT03368391 Phase 4 tetracaine HCl and oxymetazoline HCL;2% Lidocaine with 1:100,000 epinephrine;3% Mepivacaine with 1:100,000 epinephrine;saline intranasal;saline infiltration
7 A PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF THE SUPPLEMENTATION WITH KIOLIC® IN PATIENTS WITH DIAGNOSIS OF METABOLIC SYNDROME TO IMPROVE ENDOTHELIAL FUNCTION AND INFLAMMATORY STATE. "KYMES" Unknown status NCT01168700 Phase 4 aged garlic extract;Placebo
8 Effects on Incidence of Cardiovascular Events of the Addition of Pioglitazone as Compared With a Sulphonylurea in Type 2 Diabetic Patients Inadequately Controlled With Metformin. Unknown status NCT00700856 Phase 4 add-on pioglitazone;add-on sulphonylurea
9 Vitamin D Increases Serum Levels of the Soluble Receptor for Advanced Glycation End Products in Women With PCOS Completed NCT03644212 Phase 4 Vitamin D3
10 Phase 4 Cost-effectiveness Study of Beclomethasone Versus Ciclesonide as Controller Medications in Pediatric Asthma in a Hospital in Bogotá Completed NCT01333800 Phase 4 Beclomethasone;Ciclesonide
11 A Phase IV Open, Randomized, Controlled Study to Evaluate the Safety and Immunogenicity of a Pediatric Presentation (0.25 ml) of the Virosomal Hepatitis A Virus (HAV) Vaccine HAVpur in Healthy Young Children Aged Between and Including 18 Months to 47 Months, Using a 0/6 Month Immunization Schedule Completed NCT01349829 Phase 4
12 Modified Non-clarithromycin Triple Therapy in Eradicating Helicobacter Pylori Completed NCT02776371 Phase 4 Modified non-clarithromycin triple therapy;Sequential therapy
13 Study of the Effect of Calcifediol Supplementation on Left Ventricular Function in Cardiopathic Patients Undergoing Major Orthopedic Surgery. Completed NCT03403933 Phase 4 Didrogyl
14 A Randomized, Multicenter, Open-Label, Parallel-Group, 28 Days Phase IV Study Comparing The Postprandial Plasma Glucose Profile of Lixisenatide With That of Sitagliptin Add-On to Insulin Glargine in Type 2 Diabetes Mellitus Completed NCT02200991 Phase 4 LIXISENATIDE AVE0010;Sitagliptin;Insulin glargine HOE901
15 Efficacy and Safety of Risperidone Oral Solution Combination Clonazepam Versus Haloperidol IM Injection for Treatment of Acute Psychotic Agitation in Schizophrenia Completed NCT00859872 Phase 4 risperidone oral solution;haloperidol
16 Reveal® XT Performance Trial Completed NCT00680927 Phase 4
17 Respiratory Muscle Stretching in Patients With Chronic Obstructive Pulmonary Disease Submitted a Pulmonary Rehabilitation Program Completed NCT00935181 Phase 4
18 Anti-inflammatory Effects of Intracoronary and Intravenous Abciximab Administration During Primary Percutaneous Coronary Intervention.(Molecole di Adesione Nella Sindrome Coronarica Acuta Completed NCT01757457 Phase 4 Intracoronary administration of an abciximab bolus during primary PCI;Intravenous administration of an abciximab bolus during primary PCI
19 A Feasibility Study: Understanding and Altering Pain Expectations in Subjects With Osteoarthritis of the Knee or Hip Completed NCT02155257 Phase 4 Modafinil;Gabapentin;Placebo
20 Oral Nystatin Prophylaxis to Prevent Systemic Fungal Infection in Very Low Birth Weight Preterm Infants: a Randomized Controlled Trial Completed NCT03390374 Phase 4 Nystatin Oral
21 The Effect of Prior Short Course Combination Antiretroviral Therapy Administered for the Prevention of Mother-to-Child Transmission (pMTCT) of HIV-1 on Subsequent Treatment Efficacy in Treatment-"Nearly Naive" Participants Completed NCT00442962 Phase 4 Efavirenz;Emtricitabine/Tenofovir disoproxil fumarate
22 Target-controlled Infusion of Propofol and Remifentanil During General Anaesthesia Guided by Entropy of the Electroencephalogram: Comparison Between Manual Perfusion and Automated Perfusion Completed NCT00391885 Phase 4
23 Chronic Obstructive Pulmonary Disease and Weaning From Mechanical Ventilation in Difficult to Wean Patients; Randomized Prospective Study Completed NCT00355732 Phase 4
24 Prospective Randomized Trial to Evaluate the Efficacy of Donor Preconditioning With Dopamine on Initial Graft Function After Kidney Transplantation Completed NCT00115115 Phase 4 Dopamine infusion to brain dead organ donors
25 A New Strategy Regarding Discontinuation of Dual Antiplatelet; Real Safety and Efficacy of a 3-month Dual Antiplatelet Therapy Following Zotarolimus-eluting Stents Implantation (RESET Trial) Completed NCT01145079 Phase 4
26 Prospective, Randomized Clinical Trial,to Compare Standard Trabeculectomy to the Ex-PRESS Mini Glaucoma Shunt Implantation Under a Scleral Flap in Eyes With Open-Angle Glaucoma Completed NCT00698438 Phase 4
27 The Effects of Melatonin on Elevated Liver Enzymes During Statins Treatment Completed NCT03121521 Phase 4 Melatonin 10 mg;Placebo
28 A Randomized Trial Comparing Daily Atropine Versus Weekend Atropine Completed NCT00094614 Phase 4 Atropine
29 ADenosine Following Pulmonary Vein Isolation to Target Dormant Conduction Elimination: the ADVICE Trial Completed NCT01058980 Phase 4
30 Effect of Aspirin Intake on Awakening Versus at Bedtime on Circadian Rhythm of Platelet Reactivity in Healthy Subjects Completed NCT01900639 Phase 4
31 Comparison of the Effect of Fluoride Remineralizer Gel and Foam: a Randomized Clinical Trial Completed NCT02490592 Phase 4
32 Crystalloid Coload Combined With Variable Rate Phenylephrine Infusion for Prevention of Hypotension During Spinal Anesthesia for Elective Cesarean Delivery vs Crystalloid Coload Alone Completed NCT01378325 Phase 4 Phenylephrine;saline
33 A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study Evaluating the Pharmacodynamic Effect of a 6-week Treatment With Triamcinolone Acetonide Aqueous Nasal Spray 110 μg and 220 μg Once Daily on Basal Hypothalamic-Pituitary-Adrenal (HPA) Axis Function in Children [>=2 to < 12 Years of Age] With Allergic Rhinitis (AR). Completed NCT01154153 Phase 4 Placebo nasal spray;Triamcinolone acetonide aqueous (TAA-AQ) nasal spray (NASACORT AQ);Placebo nasal spray;Claritin® Syrup
34 Choroidal Thickness and Its Correlations With Ocular Parameters in Cases With Primary Open-angle Glaucoma Completed NCT03966560 Phase 4 Brimonidine Tartrate;Dorzolamide (as Dorzolamide Hydrochloride) 20 Mg/mL and Timolol (as Timolol Maleate) 5 Mg/mL Eye Drops;Brinzolamide/Timolol 10 MG/1 ML-5 MG/1 ML Ophthalmic Suspension;Travoprost and Timolol;Bimatoprost and Timolol;Latanoprost
35 Clinical Evaluation of Day and Night Skin Care Creams Supplemented With MediCell Technology (MCT)'s Composition of Defensins and Supportive Molecules Completed NCT02765763 Phase 4 2-Minute Reveal Masque;24/7 Barrier Repair Cream;8-in-1 BioSerum;Null Formula 2-Minute Reveal Masque;Null Formula 24/7 Barrier Repair Cream;Null Formula 8-in-1 BioSerum
36 Patient-controlled Intermittent Epidural Bolus Versus Epidural Infusion for Posterior Spinal Fusion After Adolescent Idiopathic Scoliosis Completed NCT02669004 Phase 4 Intermittent bolus epidural morphine;continuous epidural morphine
37 A Randomized, Double-blind, Comparator-controlled Trial to Assess the Effect of 12-week Treatment With Dapagliflozin Versus Gliclazide on Renal Physiology and Biomarkers in Metformin-treated Patients With Type 2 Diabetes Mellitus Completed NCT02682563 Phase 4 Dapagliflozin 10mg QD;Gliclazide 30mg QD
38 Randomized Trial of 24 or 48 Weeks of Peginterferon Alfa-2a Plus Ribavirin for Chronic Hepatitis C Virus Genotype 1-infected Patients in Taiwan Completed NCT00495131 Phase 4 Pegylated interferon alfa-2a plus ribavirin;Pegylated interferon alfa-2a plus ribavirin
39 Incontinence & Intimate Partners: Assessing the Contribution of Treatment Completed NCT01559389 Phase 4 Solifenacin
40 Effects of Anemia Correction on Vascular Function, Endothelial Cell Markers and Monocyte Apoptosis in Renal Transplant Recipients Completed NCT00204334 Phase 4 darbopoeitin
41 Impact of Dexmedetomidine on the Incidence of Postoperative Delirium in Patients After Cardiac Surgery: a Randomized, Double-blinded, and Placebo-controlled Clinical Trial Completed NCT02267538 Phase 4 dexmedetomidine hydrochloride for injection;0.9% sodium chloride for injection
42 Effectiveness and Safety of Inactivated EV71 Vaccine (Human Diploid Cell) in 6-71 Months Children: an Open-label Controlled Phase Ⅳ Clinical Study Completed NCT03001986 Phase 4
43 Prospective, Randomized Clinical Trial of a Silver Eluting Dressing System for Prevention of Lower Extremity Revascularization Wound Complications Completed NCT01229358 Phase 4
44 Nasally Inhaled Isopropyl Alcohol Versus Oral Ondansetron for the Treatment of Nausea in the Emergency Department: A Double-Blind Randomized Controlled Trial Completed NCT02760069 Phase 4 Inhaled isopropyl alcohol;Oral ondansetron;Inhaled normal saline;Oral placebo
45 Study of Methylphenidate to Treat Gait Disorders And Attention Deficit In Parkinson's Disease: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicentric Trial Completed NCT00914095 Phase 4 methylphenidate;placebo
46 Effects of Eplerenone on Left Ventricular Hypertrophy in Patients With Resistant Hypertension and Obstructive Sleep Apnoea Completed NCT03186742 Phase 4 Eplerenone 50 mg Tab
47 Midazolam With Meperidine and Dexmedetomidine vs Midazolam With Meperidine for Sedation During ERCP Completed NCT01404689 Phase 4 Dexmedetomidine
48 Nicotine Replacement Therapy Added to Cognitive Behavioral Therapy for Smoking Cessation in Patients With Major Mental Illness Completed NCT00320723 Phase 4 bupropion, transdermal nicotine patch
49 A Randomized Trial of Deep Neuromuscular Blockade Reversed With Sugammadex Versus Moderate Neuromuscular Block Reversed With Neostigmine, on Postoperative Quality of Recovery Completed NCT03034577 Phase 4 Sugammadex;Neostigmine
50 Phase 4 Study of Primary Use of the Vacuum Assisted Laparostomy in Treatment of Severe Peritonitis Completed NCT01531543 Phase 4

Search NIH Clinical Center for Triple X Syndrome

Genetic Tests for Triple X Syndrome

Genetic tests related to Triple X Syndrome:

# Genetic test Affiliating Genes
1 Trisomy X Syndrome 29

Anatomical Context for Triple X Syndrome

MalaCards organs/tissues related to Triple X Syndrome:

40
Breast, Lung, Kidney, Prostate, Heart, Testes, T Cells

Publications for Triple X Syndrome

Articles related to Triple X Syndrome:

(show top 50) (show all 104)
# Title Authors PMID Year
1
Symptomatic Mandibular Fibrous Dysplasia With Concurrent Triple X- and Premutation Stage Fragile-X-Syndrome: Case Report With Short Literature Survey. 61
31810942 2019
2
47, XXX syndrome with infertility, premature ovarian insufficiency, and streak ovaries. 61
31183102 2019
3
Non-invasive prenatal testing for detection of trisomy 13, 18, 21 and sex chromosome aneuploidies in 8594 cases. 61
31165466 2019
4
Sex differences in psychiatric disorders: what we can learn from sex chromosome aneuploidies. 61
30127341 2019
5
Changes in the cohort composition of turner syndrome and severe non-diagnosis of Klinefelter, 47,XXX and 47,XYY syndrome: a nationwide cohort study. 61
30642344 2019
6
Identification of paternal uniparental disomy on chromosome 22 and a de novo deletion on chromosome 18 in individuals with orofacial clefts. 61
30141273 2018
7
Behavioral and psychological features in girls and women with triple-X syndrome. 61
30070765 2018
8
Novel biallelic ATM mutations coexist with a mosaic form of triple X syndrome in an 11-year-old girl at remission after T cell acute leukemia. 61
29492593 2018
9
Vocal and gestural productions of 24-month-old children with sex chromosome trisomies. 61
28726283 2018
10
Genomics-based non-invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women. 61
29125628 2017
11
Sex chromosome aneuploidies and copy-number variants: a further explanation for neurodevelopmental prognosis variability? 61
28612834 2017
12
Generation of integration-free induced pluripotent stem cells (GZHMUi001-A) by reprogramming peripheral blood mononuclear cells from a 47, XXX syndrome patient. 61
28925367 2017
13
A finding in genetic polymorphism analysis study: A case of non-mosaic 47, XXX without manifestations. 61
28697408 2017
14
Detection of Turner syndrome using X-chromosome inactivation specific differentially methylated CpG sites: A pilot study. 61
28284085 2017
15
Noninvasive prenatal screening for fetal common sex chromosome aneuploidies from maternal blood. 61
28357876 2017
16
Cross-sectional study shows that impaired bone mineral status and metabolism are found in nonmosaic triple X syndrome. 61
28090675 2017
17
Gender balance in patients with systemic lupus erythematosus. 61
28137478 2017
18
Expanding the phenotype of Triple X syndrome: A comparison of prenatal versus postnatal diagnosis. 61
27644018 2016
19
Triple X syndrome and puberty: focus on the hypothalamus-hypophysis-gonad axis. 61
26952785 2016
20
High Myopia Associated with Triple X Syndrome. 61
27928398 2016
21
Cytogenetic studies of 1232 patients with different sexual development abnormalities from the Sultanate of Oman. 61
26706459 2016
22
Over-expression of XIST, the Master Gene for X Chromosome Inactivation, in Females With Major Affective Disorders. 61
26425698 2015
23
The Turner syndrome in patient with 45X/47XXX mosaic karyotype--case report. 61
25826153 2015
24
45,X/47,XXX Mosaicism and Short Stature. 61
26137340 2015
25
A case-control study of brain structure and behavioral characteristics in 47,XXX syndrome. 61
25287572 2014
26
Bladder exstrophy-epispadias complex and triple-X syndrome: incidental finding or causality? 61
25200913 2014
27
Structural and numerical changes of chromosome X in patients with esophageal atresia. 61
24398799 2014
28
A case associated with comorbidities among cerebral infarction, idiopathic thrombocytopenic purpura, and triple x syndrome. 61
25035678 2014
29
Craniofacial and dental manifestations of triple X syndrome associated with congenital hypothyroidism: a case report. 61
24117978 2014
30
Poor socio-economic status in 47,XXX --an unexpected effect of an extra X chromosome. 61
23542668 2013
31
Cytogenetic evaluation of patients with clinical spectrum of Turner syndrome. 61
24082654 2013
32
Fetal axillary cystic hygroma: a novel association with triple X syndrome. 61
23109196 2012
33
Triple x syndrome with short stature: case report and literature review. 61
23056899 2012
34
Mosaic triple X syndrome in a female with primary amenorrhea. 61
23162306 2012
35
Autism in association with Triple X syndrome. 61
22311144 2012
36
Triple X syndrome. 61
22755288 2012
37
The psychiatric phenotype in triple X syndrome: new hypotheses illustrated in two cases. 61
22582855 2012
38
Gilles de la Tourette's syndrome in a patient with 47(XXX) syndrome: a case report. 61
22054059 2011
39
Premature ovarian aging in primary infertility: Triple X syndrome. 61
22346085 2011
40
GM1 gangliosidosis and Morquio B disease: an update on genetic alterations and clinical findings. 61
21497194 2011
41
Application of microsatellite loci on the chromosome X for rapid prenatal detection of the chromosome X numerical abnormalities. 61
21674836 2011
42
Maternal de novo triple mosaicism for two single OCRL nucleotide substitutions (c.1736A>T, c.1736A>G) in a Lowe syndrome family. 61
21225285 2011
43
Triple X syndrome: characteristics of 42 Italian girls and parental emotional response to prenatal diagnosis. 61
20473517 2010
44
Human embryonic stem cells as models for aneuploid chromosomal syndromes. 61
20641042 2010
45
Triple X syndrome: a review of the literature. 61
19568271 2010
46
Mortality and incidence in women with 47,XXX and variants. 61
20101696 2010
47
Intestinal atresia, encephalocele, and cardiac malformations in infants with 47,XXX: Expansion of the phenotypic spectrum and a review of the literature. 61
20160426 2010
48
47,XXX/45,X/46,XX mosaicism in a patient with Turner phenotype and spontaneous puberal development. 61
19732877 2009
49
Prenatal diagnosis and prognosis of triple X syndrome: 47, XXX. 61
19762167 2009
50
Triple X syndrome in a patient with partial lipodystrophy discovered using a high-density oligonucleotide microarray: a case report. 61
19830242 2009

Variations for Triple X Syndrome

Expression for Triple X Syndrome

Search GEO for disease gene expression data for Triple X Syndrome.

Pathways for Triple X Syndrome

GO Terms for Triple X Syndrome

Sources for Triple X Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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