MCID: TBR009
MIFTS: 35

Tuberculous Empyema

Categories: Respiratory diseases

Aliases & Classifications for Tuberculous Empyema

MalaCards integrated aliases for Tuberculous Empyema:

Name: Tuberculous Empyema 12 15
Empyema, Tuberculous 44 73
Empyema Tuberculous 55

Classifications:



External Ids:

Disease Ontology 12 DOID:14305
MeSH 44 D004654
NCIt 50 C34575
SNOMED-CT 68 14527007 186184002
UMLS 73 C0014014

Summaries for Tuberculous Empyema

Disease Ontology : 12 A pleural empyema which involves presence of pus in the pleural cavity and calcified visceral pleura. It results from a large number of mycobacteria spilling into the pleural space, usually from rupture of a cavity or an adjacent paranchymal focus via a bronchopleural fistula.

MalaCards based summary : Tuberculous Empyema, also known as empyema, tuberculous, is related to pleurisy and melanoacanthoma. An important gene associated with Tuberculous Empyema is ADA (Adenosine Deaminase), and among its related pathways/superpathways are Folate Metabolism and Glucocorticoid receptor regulatory network. Affiliated tissues include lung, b cells and testes, and related phenotypes are growth/size/body region and cardiovascular system

Related Diseases for Tuberculous Empyema

Diseases related to Tuberculous Empyema via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
# Related Disease Score Top Affiliating Genes
1 pleurisy 29.9 ADA IL2
2 melanoacanthoma 10.4 CEACAM5 SALL1
3 tuberculous peritonitis 10.4 ADA CEACAM5
4 blue toe syndrome 10.3 PLG SERPINE1
5 congenital epulis 10.3 AVPR2 CEACAM5
6 dysbaric osteonecrosis 10.3 PLG SERPINE1
7 acute cor pulmonale 10.2 PLG SERPINE1
8 lemierre's syndrome 10.2 PLG SERPINE1
9 acute pulmonary heart disease 10.2 PLG SERPINE1
10 hepatic vascular disease 10.2 PLG SERPINE1
11 severe combined immunodeficiency, x-linked 10.2 ADA IL2
12 femoral neuropathy 10.2 CEACAM5 PLG
13 hepatic veno-occlusive disease 10.2 PLG SERPINE1
14 lung sarcoma 10.2 IL2 SALL1
15 thrombophilia due to activated protein c resistance 10.1 PLG SERPINE1
16 splenic tuberculosis 10.1 CEACAM5 IL2
17 lymphoma 10.1
18 primary bacterial infectious disease 10.1 ADA IL2
19 hairy cell leukemia 10.0 ADA IL2
20 inappropriate adh syndrome 10.0 AVPR2 POMC
21 combined immunodeficiency, x-linked 10.0 ADA IL2
22 syndrome of inappropriate antidiuretic hormone 10.0 AVPR2 POMC
23 diabetes insipidus, neurohypophyseal 9.9 AVPR2 POMC
24 conjunctivitis 9.9 IL2 PLG
25 ectopic cushing syndrome 9.9 AVPR2 POMC
26 lymphoma, hodgkin, classic 9.9
27 lymphoma, non-hodgkin, familial 9.9
28 pneumothorax 9.9
29 pulmonary tuberculosis 9.9
30 shwartzman phenomenon 9.9 POMC SERPINE1
31 acute thyroiditis 9.8 CEACAM5 POMC
32 arteries, anomalies of 9.8 PLG SERPINE1
33 cloacogenic carcinoma 9.8 CEACAM5 POMC
34 diabetes insipidus 9.8 AVPR2 POMC
35 b-cell lymphomas 9.7
36 diffuse large b-cell lymphoma 9.7
37 purpura 9.7
38 lymphosarcoma 9.7
39 organ system benign neoplasm 9.7 CEACAM5 POMC
40 cell type benign neoplasm 9.6 CEACAM5 POMC
41 endogenous depression 9.6 IL2 POMC
42 vernal conjunctivitis 9.6 IL2 POMC
43 overnutrition 9.6 POMC SERPINE1
44 glucose metabolism disease 9.5 POMC SERPINE1
45 cell type cancer 9.5 CEACAM5 IL2
46 pericardial tuberculosis 9.4 ADA CEACAM5 POMC
47 chronic fatigue syndrome 9.4 IL2 POMC
48 acquired metabolic disease 9.1 POMC SERPINE1

Graphical network of the top 20 diseases related to Tuberculous Empyema:



Diseases related to Tuberculous Empyema

Symptoms & Phenotypes for Tuberculous Empyema

MGI Mouse Phenotypes related to Tuberculous Empyema:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.91 POMC ADA SALL1 AVPR2 SERPINE1 IL2
2 cardiovascular system MP:0005385 9.88 POMC ADA SALL1 SERPINE1 IL2 PLG
3 hematopoietic system MP:0005397 9.8 POMC ADA AVPR2 SERPINE1 IL2 PLG
4 mortality/aging MP:0010768 9.7 POMC ADA SALL1 AVPR2 SERPINE1 IL2
5 liver/biliary system MP:0005370 9.65 POMC ADA SERPINE1 IL2 PLG
6 neoplasm MP:0002006 9.26 POMC SERPINE1 IL2 PLG
7 renal/urinary system MP:0005367 9.1 POMC ADA SALL1 SERPINE1 AVPR2 PLG

Drugs & Therapeutics for Tuberculous Empyema

Search Clinical Trials , NIH Clinical Center for Tuberculous Empyema

Cochrane evidence based reviews: empyema, tuberculous

Genetic Tests for Tuberculous Empyema

Anatomical Context for Tuberculous Empyema

MalaCards organs/tissues related to Tuberculous Empyema:

41
Lung, B Cells, Testes, Liver

Publications for Tuberculous Empyema

Articles related to Tuberculous Empyema:

(show top 50) (show all 119)
# Title Authors Year
1
Comparison of closed-chest drainage with rib resection closed drainage for treatment of chronic tuberculous empyema. ( 29600066 )
2018
2
Thoracoscopic Decortication of Stage III Tuberculous Empyema Is Effective and Safe in Selected Cases. ( 28964422 )
2017
3
Tuberculous Empyema Post Bilateral Lung Transplant. ( 28431715 )
2017
4
Salmonella houtenae-induced Empyema Complicated with Chronic Tuberculous Empyema. ( 29279480 )
2017
5
Outcomes after implementing the enhanced recovery after surgery protocol for patients undergoing tuberculous empyema operations. ( 28840005 )
2017
6
Endoscopic Bronchial Occlusion with Silicon Spigots for the Treatment of an Alveolar-pleural Fistula during Anti-tuberculosis Therapy for Tuberculous Empyema. ( 27477414 )
2016
7
Analysis of Cytokine Levers in Pleural Effusions of Tuberculous Pleurisy and Tuberculous Empyema. ( 27034588 )
2016
8
Tuberculous Empyema Necessitatis in a 40-Year-Old Immunocompetent Male. ( 27555974 )
2016
9
Treatment of Tuberculous Empyema by Intrathoracic Transposition of a Latissimus Dorsi Muscle Flap. ( 26848463 )
2016
10
50th anniversary landmark commentary on Eloesser L. Of an operation for tuberculous empyema. Ann Thorac Surg 1969;8:355-7. ( 25742809 )
2015
11
Therapeutic drug monitoring and the conservative management of chronic tuberculous empyema: case report and review of the literature. ( 26265445 )
2015
12
Diffuse Large B-cell Lymphoma Arising from Chronic Tuberculous Empyema. ( 25705606 )
2015
13
Images in emergency medicine. Woman with severe dyspnea. Tuberculous empyema. ( 25805025 )
2015
14
Application of Thoracoscopic Hybrid Surgery in the Treatment of Stage III Tuberculous Empyema. ( 26278117 )
2015
15
Outcomes of Video-Assisted Thoracic Surgical Decortication in 274 Patients with Tuberculous Empyema. ( 25818121 )
2015
16
Pseudochylous pleural effusion as a potential complication of tuberculous empyema. ( 26163079 )
2015
17
Tuberculous empyema presenting as a persistent chest wall mass: case report. ( 24432283 )
2013
18
Endobronchial Watanabe spigot embolisation in the treatment of bronchopleural fistula due to tuberculous empyema in intensive care unit. ( 22785549 )
2013
19
Intrathoracic muscular transposition in chronic tuberculous empyema. ( 22730069 )
2013
20
Evaluation of decortication in patients with chronic tuberculous empyema by three-dimensional computed tomography densitometry. ( 22388580 )
2013
21
Bilateral suspected tuberculous empyema thoracis. ( 22953307 )
2012
22
PET appearance of tuberculous empyema necessitans. ( 21892055 )
2011
23
Vesicular pleuritis in a case of tuberculous empyema thoracis. ( 21045445 )
2010
24
An operation for tuberculous empyema. 1935. ( 20162801 )
2009
25
Factors affecting morbidity in chronic tuberculous empyema. ( 18278685 )
2008
26
Treatment of a tuberculous empyema with simultaneous oral and intrapleural antituberculosis drugs. ( 18716684 )
2008
27
Tuberculous empyema necessitatis. A rare cause of cutaneous abscess in the XXI century. ( 18627713 )
2008
28
Pulmonary tuberculosis accompanied by a transient increase in serum carcinoembryonic antigen level with tuberculous empyema drainage. ( 17978537 )
2007
29
Chronic tuberculous empyema: relationships between preoperative CT findings and postoperative improvement measured by pulmonary function testing. ( 15767108 )
2005
30
Tuberculous empyema necessitatis. ( 15031577 )
2004
31
Combined spinal subdural tuberculous empyema and intramedullary tuberculoma in an HIV-positive patient. ( 12942291 )
2003
32
Rifampicin induced pneumonitis or bronchogenic spread of tuberculous empyema through a bronchopleural fistula? ( 14514951 )
2003
33
Rupture of tuberculous spinal abscess resulting in tuberculous empyema and chylothorax. ( 12815373 )
2003
34
Tuberculous empyema necessitatis in a man infected with the human immunodeficiency virus. ( 12144082 )
2002
35
Parietal pleura and extrapleural space in chronic tuberculous empyema: CT-pathologic correlation. ( 11176286 )
2001
36
Tuberculous pleural effusion and tuberculous empyema. ( 16088708 )
2001
37
Management of tuberculous empyema. ( 10758384 )
2000
38
Tuberculous empyema. ( 10197400 )
1999
39
Tuberculous empyema. ( 10201053 )
1998
40
Malignant lymphoma arising from chronic tuberculous empyema. A case report. ( 9332239 )
1997
41
Primary Epstein-Barr virus-related non-Hodgkin's lymphoma of the pleural cavity following long-standing tuberculous empyema. ( 8629908 )
1996
42
Open drainage of massive tuberculous empyema with progressive reexpansion of the lung: an old concept revisited. ( 8678646 )
1996
43
[Prognosis of the surgical treatment for non-Hodgkin lymphoma originating from chronic tuberculous empyema--analysis of 11 cases with pleuropneumonectomy]. ( 8666866 )
1996
44
Tuberculous empyema presenting after oleothorax. ( 7709003 )
1995
45
Fast spin-echo MR imaging of non-Hodgkin lymphoma arising from chronic tuberculous empyema. ( 7891400 )
1995
46
Failure of drug penetration and acquisition of drug resistance in chronic tuberculous empyema. ( 7496011 )
1995
47
Treatment of tuberculous empyema with multiple fistulae by reexpansion of the affected lung and restoration of its function: report of a case. ( 7949781 )
1994
48
Tuberculous empyema presenting 62 years after oleothorax: a case report. ( 8036309 )
1994
49
The "reversed" latissimus dorsi muscle flap with conditioning delay for closure of a lower thoracic tuberculous empyema. ( 7940490 )
1994
50
Results of surgical treatment for calcified tuberculous empyema: improved pulmonary function obtained with lung preserving policy. ( 8160180 )
1993

Variations for Tuberculous Empyema

Expression for Tuberculous Empyema

Search GEO for disease gene expression data for Tuberculous Empyema.

Pathways for Tuberculous Empyema

Pathways related to Tuberculous Empyema according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.66 IL2 PLG SERPINE1
2 11.28 IL2 POMC
3 11.11 PLG SERPINE1
4 10.89 CEACAM5 PLG SERPINE1
5 10.85 CEACAM5 PLG
6 10.07 PLG SERPINE1

GO Terms for Tuberculous Empyema

Cellular components related to Tuberculous Empyema according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.02 ADA IL2 PLG POMC SERPINE1
2 platelet alpha granule lumen GO:0031093 8.96 PLG SERPINE1

Biological processes related to Tuberculous Empyema according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription by RNA polymerase II GO:0045944 9.71 IL2 POMC SALL1 SERPINE1
2 regulation of signaling receptor activity GO:0010469 9.63 IL2 POMC SERPINE1
3 positive regulation of inflammatory response GO:0050729 9.43 IL2 SERPINE1
4 hemostasis GO:0007599 9.37 AVPR2 PLG
5 positive regulation of B cell proliferation GO:0030890 9.32 ADA IL2
6 fibrinolysis GO:0042730 9.26 PLG SERPINE1
7 positive regulation of T cell differentiation GO:0045582 9.16 ADA IL2
8 embryonic digestive tract development GO:0048566 8.96 ADA SALL1
9 negative regulation of fibrinolysis GO:0051918 8.62 PLG SERPINE1

Molecular functions related to Tuberculous Empyema according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 8.8 PLG POMC SERPINE1

Sources for Tuberculous Empyema

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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