MCID: TBR009
MIFTS: 35

Tuberculous Empyema

Categories: Respiratory diseases

Aliases & Classifications for Tuberculous Empyema

MalaCards integrated aliases for Tuberculous Empyema:

Name: Tuberculous Empyema 12 15 17
Empyema, Tuberculous 45 74
Empyema Tuberculous 56

Classifications:



External Ids:

Disease Ontology 12 DOID:14305
MeSH 45 D004654
NCIt 51 C34575
SNOMED-CT 69 14527007
UMLS 74 C0014014

Summaries for Tuberculous Empyema

Disease Ontology : 12 A pleural empyema which involves presence of pus in the pleural cavity and calcified visceral pleura. It results from a large number of mycobacteria spilling into the pleural space, usually from rupture of a cavity or an adjacent paranchymal focus via a bronchopleural fistula.

MalaCards based summary : Tuberculous Empyema, also known as empyema, tuberculous, is related to pleurisy and pulmonary tuberculosis. An important gene associated with Tuberculous Empyema is ADA (Adenosine Deaminase), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Selenium Micronutrient Network. Affiliated tissues include b cells, neutrophil and testes, and related phenotypes are growth/size/body region and cardiovascular system

Related Diseases for Tuberculous Empyema

Diseases related to Tuberculous Empyema via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
# Related Disease Score Top Affiliating Genes
1 pleurisy 29.7 ADA IL2
2 pulmonary tuberculosis 29.4 ADA IL2
3 pleural empyema 10.9
4 lymphoma 10.2
5 melanoacanthoma 10.2 CEACAM5 SALL1
6 tuberculous peritonitis 10.2 ADA CEACAM5
7 blue toe syndrome 10.1 PLG SERPINE1
8 congenital epulis 10.1 AVPR2 CEACAM5
9 pleural disease 10.1 ADA CEACAM5
10 dysbaric osteonecrosis 10.1 PLG SERPINE1
11 livedoid vasculitis 10.1 PLG SERPINE1
12 acute cor pulmonale 10.1 PLG SERPINE1
13 acute pulmonary heart disease 10.1 PLG SERPINE1
14 lemierre's syndrome 10.1 PLG SERPINE1
15 inappropriate adh syndrome 10.1 AVPR2 POMC
16 hepatic vascular disease 10.1 PLG SERPINE1
17 syndrome of inappropriate antidiuretic hormone 10.1 AVPR2 POMC
18 femoral neuropathy 10.1 CEACAM5 PLG
19 hepatic veno-occlusive disease 10.1 PLG SERPINE1
20 diabetes insipidus, neurohypophyseal 10.1 AVPR2 POMC
21 diabetes insipidus 10.1 AVPR2 POMC
22 vein disease 10.1 PLG SERPINE1
23 ectopic cushing syndrome 10.1 AVPR2 POMC
24 thrombophilia due to activated protein c resistance 10.0 PLG SERPINE1
25 lymphoma, hodgkin, classic 10.0
26 lymphoma, non-hodgkin, familial 10.0
27 pneumothorax 10.0
28 arteries, anomalies of 10.0 PLG SERPINE1
29 severe combined immunodeficiency, x-linked 10.0 ADA IL2
30 combined t cell and b cell immunodeficiency 10.0 ADA IL2
31 overnutrition 9.9 POMC SERPINE1
32 cell type benign neoplasm 9.9 CEACAM5 POMC
33 primary bacterial infectious disease 9.9 ADA IL2
34 splenic tuberculosis 9.9 CEACAM5 IL2
35 hairy cell leukemia 9.9 ADA IL2
36 glucose metabolism disease 9.9 POMC SERPINE1
37 conjunctivitis 9.9 IL2 PLG
38 diffuse large b-cell lymphoma 9.9
39 subdural empyema 9.9
40 purpura 9.9
41 berylliosis 9.9 IL2 POMC
42 speech and communication disorders 9.9 PLG POMC
43 pericardial tuberculosis 9.8 ADA CEACAM5 POMC
44 vernal conjunctivitis 9.8 IL2 POMC
45 acquired metabolic disease 9.8 POMC SERPINE1
46 chronic fatigue syndrome 9.7 IL2 POMC
47 intestinal disease 9.7 CEACAM5 IL2
48 urinary system disease 9.7 IL2 POMC

Graphical network of the top 20 diseases related to Tuberculous Empyema:



Diseases related to Tuberculous Empyema

Symptoms & Phenotypes for Tuberculous Empyema

MGI Mouse Phenotypes related to Tuberculous Empyema:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.91 ADA AVPR2 IL2 PLG POMC SALL1
2 cardiovascular system MP:0005385 9.88 ADA IL2 PLG POMC SALL1 SERPINE1
3 hematopoietic system MP:0005397 9.8 ADA AVPR2 IL2 PLG POMC SERPINE1
4 mortality/aging MP:0010768 9.7 ADA AVPR2 IL2 PLG POMC SALL1
5 liver/biliary system MP:0005370 9.65 ADA IL2 PLG POMC SERPINE1
6 neoplasm MP:0002006 9.26 IL2 PLG POMC SERPINE1
7 renal/urinary system MP:0005367 9.1 ADA AVPR2 PLG POMC SALL1 SERPINE1

Drugs & Therapeutics for Tuberculous Empyema

Search Clinical Trials , NIH Clinical Center for Tuberculous Empyema

Cochrane evidence based reviews: empyema, tuberculous

Genetic Tests for Tuberculous Empyema

Anatomical Context for Tuberculous Empyema

MalaCards organs/tissues related to Tuberculous Empyema:

42
B Cells, Neutrophil, Testes, T Cells

Publications for Tuberculous Empyema

Articles related to Tuberculous Empyema:

(show top 50) (show all 128)
# Title Authors Year
1
Treatment of chronic tuberculous empyema by intrapleural injection of anhydrous ethanol. ( 30505678 )
2019
2
Tuberculous Empyema Necessitatis. ( 30847490 )
2019
3
Salmonella houtenae-induced Empyema Complicated with Chronic Tuberculous Empyema. ( 29279480 )
2018
4
Comparison of closed-chest drainage with rib resection closed drainage for treatment of chronic tuberculous empyema. ( 29600066 )
2018
5
Reply: a typical manifestations of tuberculous empyema an neutrophil-predominant effusions. ( 30165391 )
2018
6
Atypical manifestations of tuberculous empyema and neutrophil-predominant tuberculous pleural effusions. ( 30165694 )
2018
7
Tuberculous Empyema Post Bilateral Lung Transplant. ( 28431715 )
2017
8
Outcomes after implementing the enhanced recovery after surgery protocol for patients undergoing tuberculous empyema operations. ( 28840005 )
2017
9
Thoracoscopic Decortication of Stage III Tuberculous Empyema Is Effective and Safe in Selected Cases. ( 28964422 )
2017
10
Analysis of Cytokine Levers in Pleural Effusions of Tuberculous Pleurisy and Tuberculous Empyema. ( 27034588 )
2016
11
Pseudochylous pleural effusion as a potential complication of tuberculous empyema. ( 26163079 )
2016
12
Treatment of Tuberculous Empyema by Intrathoracic Transposition of a Latissimus Dorsi Muscle Flap. ( 26848463 )
2016
13
Endoscopic Bronchial Occlusion with Silicon Spigots for the Treatment of an Alveolar-pleural Fistula during Anti-tuberculosis Therapy for Tuberculous Empyema. ( 27477414 )
2016
14
Tuberculous Empyema Necessitatis in a 40-Year-Old Immunocompetent Male. ( 27555974 )
2016
15
Diffuse Large B-cell Lymphoma Arising from Chronic Tuberculous Empyema. ( 25705606 )
2015
16
50th anniversary landmark commentary on Eloesser L. Of an operation for tuberculous empyema. Ann Thorac Surg 1969;8:355-7. ( 25742809 )
2015
17
Images in emergency medicine. Woman with severe dyspnea. Tuberculous empyema. ( 25805025 )
2015
18
Outcomes of Video-Assisted Thoracic Surgical Decortication in 274 Patients with Tuberculous Empyema. ( 25818121 )
2015
19
Therapeutic drug monitoring and the conservative management of chronic tuberculous empyema: case report and review of the literature. ( 26265445 )
2015
20
Application of Thoracoscopic Hybrid Surgery in the Treatment of Stage III Tuberculous Empyema. ( 26278117 )
2015
21
Evaluation of decortication in patients with chronic tuberculous empyema by three-dimensional computed tomography densitometry. ( 22388580 )
2013
22
Intrathoracic muscular transposition in chronic tuberculous empyema. ( 22730069 )
2013
23
Endobronchial Watanabe spigot embolisation in the treatment of bronchopleural fistula due to tuberculous empyema in intensive care unit. ( 22785549 )
2013
24
Tuberculous empyema presenting as a persistent chest wall mass: case report. ( 24432283 )
2013
25
Bilateral suspected tuberculous empyema thoracis. ( 22953307 )
2012
26
PET appearance of tuberculous empyema necessitans. ( 21892055 )
2011
27
Vesicular pleuritis in a case of tuberculous empyema thoracis. ( 21045445 )
2010
28
Factors affecting morbidity in chronic tuberculous empyema. ( 18278685 )
2008
29
Tuberculous empyema necessitatis. A rare cause of cutaneous abscess in the XXI century. ( 18627713 )
2008
30
Treatment of a tuberculous empyema with simultaneous oral and intrapleural antituberculosis drugs. ( 18716684 )
2008
31
Pulmonary tuberculosis accompanied by a transient increase in serum carcinoembryonic antigen level with tuberculous empyema drainage. ( 17978537 )
2007
32
Chronic tuberculous empyema: relationships between preoperative CT findings and postoperative improvement measured by pulmonary function testing. ( 15767108 )
2005
33
Tuberculous empyema necessitatis. ( 15031577 )
2004
34
Rupture of tuberculous spinal abscess resulting in tuberculous empyema and chylothorax. ( 12815373 )
2003
35
Combined spinal subdural tuberculous empyema and intramedullary tuberculoma in an HIV-positive patient. ( 12942291 )
2003
36
Rifampicin induced pneumonitis or bronchogenic spread of tuberculous empyema through a bronchopleural fistula? ( 14514951 )
2003
37
Tuberculous empyema necessitatis in a man infected with the human immunodeficiency virus. ( 12144082 )
2002
38
Parietal pleura and extrapleural space in chronic tuberculous empyema: CT-pathologic correlation. ( 11176286 )
2001
39
Tuberculous pleural effusion and tuberculous empyema. ( 16088708 )
2001
40
Management of tuberculous empyema. ( 10758384 )
2000
41
Tuberculous empyema. ( 10197400 )
1999
42
Tuberculous empyema. ( 10201053 )
1998
43
Malignant lymphoma arising from chronic tuberculous empyema. A case report. ( 9332239 )
1997
44
Primary Epstein-Barr virus-related non-Hodgkin's lymphoma of the pleural cavity following long-standing tuberculous empyema. ( 8629908 )
1996
45
Open drainage of massive tuberculous empyema with progressive reexpansion of the lung: an old concept revisited. ( 8678646 )
1996
46
[Prognosis of the surgical treatment for non-Hodgkin lymphoma originating from chronic tuberculous empyema--analysis of 11 cases with pleuropneumonectomy]. ( 8666866 )
1996
47
Failure of drug penetration and acquisition of drug resistance in chronic tuberculous empyema. ( 7496011 )
1995
48
Tuberculous empyema presenting after oleothorax. ( 7709003 )
1995
49
Fast spin-echo MR imaging of non-Hodgkin lymphoma arising from chronic tuberculous empyema. ( 7891400 )
1995
50
The "reversed" latissimus dorsi muscle flap with conditioning delay for closure of a lower thoracic tuberculous empyema. ( 7940490 )
1994

Variations for Tuberculous Empyema

Expression for Tuberculous Empyema

Search GEO for disease gene expression data for Tuberculous Empyema.

Pathways for Tuberculous Empyema

GO Terms for Tuberculous Empyema

Cellular components related to Tuberculous Empyema according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.55 CEACAM5 IL2 PLG POMC SERPINE1
2 extracellular space GO:0005615 9.02 ADA IL2 PLG POMC SERPINE1
3 platelet alpha granule lumen GO:0031093 8.96 PLG SERPINE1

Biological processes related to Tuberculous Empyema according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription by RNA polymerase II GO:0045944 9.71 IL2 POMC SALL1 SERPINE1
2 regulation of signaling receptor activity GO:0010469 9.63 IL2 POMC SERPINE1
3 positive regulation of inflammatory response GO:0050729 9.43 IL2 SERPINE1
4 hemostasis GO:0007599 9.37 AVPR2 PLG
5 positive regulation of B cell proliferation GO:0030890 9.32 ADA IL2
6 fibrinolysis GO:0042730 9.26 PLG SERPINE1
7 positive regulation of T cell differentiation GO:0045582 9.16 ADA IL2
8 embryonic digestive tract development GO:0048566 8.96 ADA SALL1
9 negative regulation of fibrinolysis GO:0051918 8.62 PLG SERPINE1

Molecular functions related to Tuberculous Empyema according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 8.8 PLG POMC SERPINE1

Sources for Tuberculous Empyema

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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