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MCID: TBR003
MIFTS: 32

Tuberculous Epididymitis

Categories: Infectious diseases, Reproductive diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes
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Aliases & Classifications for Tuberculous Epididymitis

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MalaCards integrated aliases for Tuberculous Epididymitis:

Name: Tuberculous Epididymitis 12 15
Tuberculosis of Epididymis 71

Classifications:

MalaCards categories:
Global: Infectious diseases
Anatomical: Reproductive diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:1251
ICD9CM 34 016.4
SNOMED-CT 67 83652003
UMLS 71 C0152814
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Summaries for Tuberculous Epididymitis

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Disease Ontology : 12 An urogenital tuberculosis that is located in epididymis, has symptom pain and has symptom scrotal swelling.

MalaCards based summary : Tuberculous Epididymitis, also known as tuberculosis of epididymis, is related to epididymo-orchitis and pyuria, and has symptoms including pain and scrotal swelling. An important gene associated with Tuberculous Epididymitis is CGB3 (Chorionic Gonadotropin Subunit Beta 3), and among its related pathways/superpathways are Overview of nanoparticle effects and Transcription_Role of VDR in regulation of genes involved in osteoporosis. Affiliated tissues include epididymis, prostate and skin, and related phenotypes are cardiovascular system and homeostasis/metabolism

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Related Diseases for Tuberculous Epididymitis

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Diseases related to Tuberculous Epididymitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 172)
# Related Disease Score Top Affiliating Genes
1 epididymo-orchitis 30.5 KLK3 CRP AFP
2 pyuria 30.5 KLK3 CRP
3 anal fistula 30.2 TNF AFP
4 pulmonary tuberculosis 29.7 VDR TNF CRP
5 acquired immunodeficiency syndrome 29.7 TNF POMC CRP
6 extrapulmonary tuberculosis 29.3 VDR TNF CRP
7 mixed germ cell tumor 10.5 CGB3 AFP
8 testicular seminoma 10.5 CGB3 AFP
9 chromosomal triplication 10.5 CGB3 AFP
10 liver inflammatory pseudotumor 10.4 CRP AFP
11 testicular infarct 10.4 CRP AFP
12 hematocele of tunica vaginalis testis 10.4 CRP AFP
13 infected hydrocele 10.4 CRP AFP
14 lung oat cell carcinoma 10.4 POMC AVP
15 cardiac tuberculosis 10.4 EHD1 CRP
16 pituitary infarct 10.4 POMC AVP
17 mediastinum teratoma 10.4 POMC CRP
18 glossopharyngeal nerve paralysis 10.4 KLK3 AFP
19 paralytic ileus 10.4 CRP AVP
20 hypothalamic disease 10.4 POMC AVP
21 cavernous sinus thrombosis 10.3 POMC CRP
22 olfactory nerve neoplasm 10.3 POMC AVP
23 cranial nerve malignant neoplasm 10.3 POMC AVP
24 orbital cellulitis 10.3 POMC CRP
25 acute orbital inflammation 10.3 POMC CRP
26 abducens nerve disease 10.3 POMC CRP
27 arachnoiditis 10.3 POMC CRP
28 sheehan syndrome 10.3 POMC AVP
29 epididymis adenocarcinoma 10.3 KLK3 AFP
30 epididymis cancer 10.3 KLK3 AFP
31 cranial nerve neoplasm 10.3 POMC AVP
32 anorectal stricture 10.3 ZNF77 TNF
33 prostate adenoid cystic carcinoma 10.3 POMC KLK3
34 atypical depressive disorder 10.3 POMC CRP
35 germinoma 10.3 CGB3 AVP AFP
36 dental abscess 10.3 CYP27B1 CRP
37 drug reaction with eosinophilia and systemic symptoms 10.3 TNF CRP
38 inappropriate adh syndrome 10.2 POMC AVP
39 rheumatoid arthritis interstitial lung disease 10.2 TNF CRP
40 posterior scleritis 10.2 TNF CRP
41 louse-borne relapsing fever 10.2 TNF CRP
42 bladder cancer 10.2
43 orchitis 10.2
44 hydrocele 10.2
45 opportunistic bacterial infectious disease 10.2 TNF CRP
46 gastrointestinal tuberculosis 10.2 TNF CRP
47 intestinal tuberculosis 10.2 TNF CRP
48 cerebritis 10.2 TNF CRP
49 nocardiosis 10.2 TNF CRP
50 granulomatous hepatitis 10.2 TNF CRP

Graphical network of the top 20 diseases related to Tuberculous Epididymitis:



Diseases related to Tuberculous Epididymitis
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Symptoms & Phenotypes for Tuberculous Epididymitis

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Symptoms:

12
  • • pain
  • • scrotal swelling

MGI Mouse Phenotypes related to Tuberculous Epididymitis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.76 CAPNS1 CD2AP CRP KLK3 PLEKHG5 POMC
2 homeostasis/metabolism MP:0005376 9.7 AFP AVP CAPNS1 CD2AP CRP CYP27B1
3 renal/urinary system MP:0005367 9.1 AVP CD2AP CYP27B1 PLEKHG5 POMC VDR
Sources

Drugs & Therapeutics for Tuberculous Epididymitis

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Search Clinical Trials , NIH Clinical Center for Tuberculous Epididymitis

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Genetic Tests for Tuberculous Epididymitis

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Anatomical Context for Tuberculous Epididymitis

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The Foundational Model of Anatomy Ontology organs/tissues related to Tuberculous Epididymitis:

19
Epididymis

MalaCards organs/tissues related to Tuberculous Epididymitis:

40
Prostate, Skin, Testis, Testes
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Publications for Tuberculous Epididymitis

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Articles related to Tuberculous Epididymitis:

(show top 50) (show all 108)
# Title Authors PMID Year
1
Nodular granulomatous phlebitis of the penis in a patient with antecedent tuberculous epididymitis: The first reported case. 61
31245863 2019
2
Histopathological Spectrum of Tumor and 
Tumor-like Lesions of the Paratestis in a 
Tertiary Care Hospital. 61
26674546 2015
3
Tuberculous Epididymitis. 61
25945724 2015
4
Tuberculous Epididymitis: A Case of Tuberculous Epididymitis That Was the Presenting Manifestation of Extrapulmonary and Pulmonary Tuberculoses. 61
25851823 2015
5
[Tuberculous epididymitis after Bacillus Calmette-Guérin intravesical therapy : a case report]. 61
25001646 2014
6
Sonographic findings of tuberculous vasitis. 61
24764347 2014
7
Unusual isolated tubercolous epididymitis. Case report. 61
24979105 2014
8
[IFN-gamma enzyme-linked immunospot assay versus PPD tuberculin skin test in the diagnosis of tuberculous epididymitis]. 61
22774610 2012
9
Tuberculous epididymitis. 61
22634794 2012
10
Isolated tuberculous epididymitis presenting as a painless scrotal tumor. 61
22721625 2012
11
[A case of tuberculous epididymitis after Bacillus Calmette-Guérin intravesical instillation therapy for bladder cancer]. 61
22450841 2012
12
Tuberculous epididymitis-cytology-based diagnosis. 61
22670514 2012
13
[Unusual locations of tuberculosis: three case reports]. 61
19233520 2009
14
Tuberculous epididymitis presenting as huge scrotal tumor. 61
18619652 2009
15
Tuberculous epididymitis following intravesical Bacillus Calmette-Guérin immunotherapy. 61
19364433 2009
16
Isolated tuberculous epididymitis masquerading as a scrotal tumor. 61
19255699 2008
17
[Diagnosis and treatment of isolated tuberculous epididymitis]. 61
19157104 2008
18
[Case of tuberculous epididymitis caused by intravesical BCG therapy]. 61
18975579 2008
19
Tuberculous epididymo-orchitis and prostatitis: a case report. 61
18336455 2008
20
[The first "fillers", vaseline and paraffin. From miracle to disaster]. 61
16860452 2007
21
Fine needle aspiration of epididymal nodules in Chandigarh, north India: an audit of 228 cases. 61
16879267 2006
22
Tuberculous epididymitis presenting with Addison's disease: a rare case. 61
16895290 2006
23
[Diagnosis and differential diagnosis value of ultrasound in epididymal mass]. 61
16519159 2006
24
[Bilateral tuberculous epididymitis after intravesical Bacillus Calmette-Guerin therapy]. 61
16440736 2005
25
Tuberculosis, bronchiectasis, and infertility: what ailed George Orwell? 61
16267732 2005
26
Tuberculous epididymitis: a case report and literature review. 61
16110362 2005
27
Tuberculous epididymitis and fertility in North Jordan. 61
16127515 2005
28
Isolated tuberculous epididymitis: a review of forty cases. 61
16006701 2005
29
Painless scrotal swelling: ultrasonographical features with pathological correlation. 61
15800728 2005
30
Fine-needle aspiration cytology versus open biopsy for evaluation of chronic epididymal lesions: a prospective study. 61
16118093 2005
31
Tuberculous epididymitis with extensive retroperitoneal and mediastinal involvement. 61
15245961 2004
32
Tuberculous epididymitis associated with abdominal lymphadenopathy (2004:1b). 61
15085800 2004
33
[Tuberculous epididymitis caused by intravesical BCG therapy: a case report]. 61
14598693 2003
34
[Tuberculous epididymitis caused by Mycobacterium bovis]. 61
12731446 2003
35
Differential diagnosis of focal epididymal lesions with gray scale sonographic, color Doppler sonographic, and clinical features. 61
12562118 2003
36
[Epididymal tuberculosis: report of a case with particular color Doppler ultrasonography finding]. 61
12611141 2002
37
[Tuberculous epididymitis following intravesical Bacillus Calmette-Guérin therapy]. 61
12056045 2002
38
[Orchiectomy for tuberculous epididymitis: a report of two cases with intractable to antituberculosis treatment]. 61
11712389 2001
39
Tuberculous epididymitis and epididymo-orchitis: sonographic appearances. 61
11373214 2001
40
[A case of tuberculosis of the prostate presenting as endoscopically cavitary change]. 61
11449704 2001
41
[Lymphotropic therapy with antitubercular agents in the treatment of tuberculous epididymitis]. 61
11523363 2001
42
Chronic tuberculous epididymitis: color Doppler US findings with histopathologic correlation. 61
10931999 2000
43
[A case of tuberculous epididymitis which was difficult to distinguish from a testicular tumor]. 61
11019378 2000
44
Serious complications of tuberculous epididymitis. 61
10879650 2000
45
The outcome of sperm retrieval and intracytoplasmic sperm injection in patients with obstructive azoospermia: impact of previous tuberculous epididymitis. 61
10478323 1999
46
[Epididymal manifestations of urogenital tuberculosis]. 61
9615934 1998
47
Sonographic findings in tuberculous epididymitis and epididymo-orchitis. 61
9282805 1997
48
Treatment of tuberculous epididymitis by intratunical rifampicin injection. 61
8743356 1996
49
[Epididymal manifestations of urogenital tuberculosis]. 61
9827094 1996
50
Tuberculous epididymitis presenting as acute hydrocele. 61
7562703 1995
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Variations for Tuberculous Epididymitis

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Expression for Tuberculous Epididymitis

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Search GEO for disease gene expression data for Tuberculous Epididymitis.
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Pathways for Tuberculous Epididymitis

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Pathways related to Tuberculous Epididymitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Overview of nanoparticle effects 1
10.54 TNF CRP
2
Transcription_Role of VDR in regulation of genes involved in osteoporosis 22
10.45 VDR TNF CYP27B1
3
RXR and RAR heterodimerization with other nuclear receptor 1
10.3 VDR TNF
4
Vitamin D Metabolism 1
9.96 VDR CYP27B1
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GO Terms for Tuberculous Epididymitis

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Cellular components related to Tuberculous Epididymitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.5 TNF POMC KLK3 CRP CGB3 AVP
2 secretory granule GO:0030141 9.33 POMC KLK3 AVP
3 endocytic vesicle GO:0030139 8.8 PLEKHG5 EHD1 CD2AP

Biological processes related to Tuberculous Epididymitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of keratinocyte differentiation GO:0045618 9.26 VDR CYP27B1
2 vitamin D metabolic process GO:0042359 9.16 VDR CYP27B1
3 negative regulation of lipid storage GO:0010888 8.96 TNF CRP
4 positive regulation of vitamin D 24-hydroxylase activity GO:0010980 8.62 VDR CYP27B1

Molecular functions related to Tuberculous Epididymitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.8 POMC CGB3 AVP
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Sources for Tuberculous Epididymitis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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