Tuberculum Sellae Meningioma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Tuberculum Sellae Meningioma

MalaCards integrated aliases for Tuberculum Sellae Meningioma:

Name: Tuberculum Sellae Meningioma ¹¹ ¹⁴ ⁷¹

Meningioma of the Tuberculum Sellae ¹¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Bone diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:7713

NCIt ⁴⁹ C5284

UMLS ⁷¹ C1336829

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Summaries for Tuberculum Sellae Meningioma

MalaCards based summary: Tuberculum Sellae Meningioma, also known as meningioma of the tuberculum sellae, is related to meningioma, familial and abducens palsy, and has symptoms including headache and seizures. An important gene associated with Tuberculum Sellae Meningioma is POMC (Proopiomelanocortin), and among its related pathways/superpathways are Prader-Willi and Angelman syndrome and Splicing factor NOVA regulated synaptic proteins. Affiliated tissues include bone, pituitary and caudate nucleus, and related phenotype is liver/biliary system.

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Related Diseases for Tuberculum Sellae Meningioma

Diseases related to Tuberculum Sellae Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 131)

#	Related Disease	Score	Top Affiliating Genes
1	meningioma, familial	30.9	TRAF7 PRL POMC NF2 EPB41
2	abducens palsy	30.5	PRL POMC
3	olfactory groove meningioma	30.5	TRAF7 NF2
4	angiomatous meningioma	30.5	TRAF7 NF2
5	skull base meningioma	30.5	TRAF7 NF2
6	central diabetes insipidus	30.4	PRL POMC
7	pituitary adenoma	30.4	PRL POMC GHRH
8	adenoma	30.3	PRL POMC GHRH
9	pituitary hormone deficiency, combined, 2	29.9	PRL POMC GHRH
10	cerebrospinal fluid leak	10.6
11	3-methylglutaconic aciduria, type iii	10.5
12	vascular disease	10.4
13	pituitary tumors	10.4
14	prostate cancer	10.2
15	hypothyroidism, congenital, nongoitrous, 2	10.2
16	moyamoya disease 1	10.2
17	thyrotropin-releasing hormone deficiency	10.2
18	lymphoproliferative syndrome, x-linked, 1	10.2
19	hypothyroidism, congenital, nongoitrous, 3	10.2
20	ptosis	10.2
21	uveitis	10.2
22	optic nerve disease	10.2
23	hyperostosis	10.2
24	psychotic disorder	10.2
25	gastric antral vascular ectasia	10.2
26	hemangioma	10.2
27	toxic encephalopathy	10.2
28	neuropathy	10.2
29	diabetes insipidus	10.2
30	bacterial meningitis	10.2
31	suprasellar meningioma	10.2	POMC NF2
32	chiasmal syndrome	10.1	PRL POMC
33	cranial nerve malignant neoplasm	10.1	POMC NF2
34	prolactin producing pituitary tumor	10.1	PRL POMC
35	sphenoorbital meningioma	10.1	TRAF7 NF2
36	foramen magnum meningioma	10.1	TRAF7 NF2
37	acidophil adenoma	10.1	PRL POMC
38	chromophobe adenoma	10.1	PRL POMC
39	ectopic cushing syndrome	10.1	PRL POMC
40	childhood meningioma	10.1	TRAF7 NF2
41	cavernous sinus meningioma	10.1	TRAF7 NF2
42	cerebral falx meningioma	10.1	TRAF7 NF2
43	psammomatous meningioma	10.1	TRAF7 NF2
44	parasagittal meningioma	10.1	TRAF7 NF2
45	tsh producing pituitary tumor	10.1	PRL POMC
46	microcystic meningioma	10.1	TRAF7 NF2
47	intraventricular meningioma	10.1	TRAF7 NF2
48	cerebral convexity meningioma	10.1	TRAF7 NF2
49	optic nerve sheath meningioma	10.1	TRAF7 NF2
50	sheehan syndrome	10.1	PRL POMC

Graphical network of the top 20 diseases related to Tuberculum Sellae Meningioma:

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Symptoms & Phenotypes for Tuberculum Sellae Meningioma

UMLS symptoms related to Tuberculum Sellae Meningioma:

headache; seizures

MGI Mouse Phenotypes related to Tuberculum Sellae Meningioma:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	liver/biliary system	MP:0005370	9.02	EPB41 GHRH NF2 POMC PRL

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Drugs & Therapeutics for Tuberculum Sellae Meningioma

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Paraoptic Tumors : Study of the Radiological, Ophthalmological and Intraoperative Predictive Factors of Visual Recovery After Neurosurgical Removal	Recruiting	NCT03567486

Search NIH Clinical Center for Tuberculum Sellae Meningioma

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Genetic Tests for Tuberculum Sellae Meningioma

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Anatomical Context for Tuberculum Sellae Meningioma

Organs/tissues related to Tuberculum Sellae Meningioma:

MalaCards : Bone, Pituitary, Caudate Nucleus, Brain, Prostate, Kidney

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Publications for Tuberculum Sellae Meningioma

Articles related to Tuberculum Sellae Meningioma:

(show top 50) (show all 186)

#	Title	Authors	PMID	Year
1	Treatment of Intracranial Tumors With Stereotactic Radiosurgery: Short-Term Results From Cuba. ⁶²	Alvarez Aquino A...Chaurasia B	36348852	2022
2	Does Endoscopic Transnasal Optic Nerve Decompression Followed by Radiosurgery Improve Outcomes in the Treatment of Parasellar Meningiomas? ⁶²	Matousek P...Krejci T	36013604	2022
3	Microsurgical Resection of Tuberculum Sellae Meningioma through Pterional Approach with Extradural Optic Canal Unroofing. ⁶²	Matsuo S...Nakamizo A	36068909	2022
4	Predictive Factors of Favorable Visual Outcomes After Surgery of Tuberculum Sellae Meningiomas: A Multicenter Retrospective Cohort Study. ⁶²	Leclerc A...Emery E	35568126	2022
5	Contralateral subfrontal approach for tuberculum sellae meningioma: techniques and clinical outcomes. ⁶²	Kim YJ...Jung S	35901684	2022
6	Optical coherence tomography as a useful adjunct in the early detection of meningioma with optic nerve compression. ⁶²	Chang EC...Wang IH	36248089	2022
7	Management of Internal Carotid Artery Injury During Transsphenoidal Surgery: A Case Series and Suggestion for Optimal Management. ⁶²	Hong CK...Kim JH	35364296	2022
8	How I do it: optic canal unroofing in surgery for tuberculum sellae meningiomas with compression of the optic nerve. ⁶²	Kozak J...Klener J	35094145	2022
9	Modified Shoelace Dural Closure with Collagen Matrix in Extended Transsphenoidal Surgery. ⁶²	Nagata Y...Saito R	35296586	2022
10	Skull Base Approaches for Tuberculum Sellae Meningiomas: Institutional Experience in a Series of 34 Patients. ⁶²	Alam S...Chaurasia B	35454983	2022
11	Dural metastasis from prostate carcinoma mimicking tuberculum sellae meningioma: A case report. ⁶²	Kobayashi M...Nakada M	36324921	2022
12	Comparison of the Efficacy and Safety of Neuroendoscopic Endonasal Transsphenoidal Surgeries and Intracranial Endoscopic Pterional Approach in Resection of Tuberculum Sellae Meningiomas. ⁶²	Lin Z...Guo A	35711498	2022
13	Improvement of optic nerve pial blood supply visualized through indocyanine green videoangiography after resection of a tuberculum sellae meningioma: 2-dimensional operative video. ⁶²	Ceccato GHW...Borba LAB	36284583	2022
14	Keyhole supraorbital eyebrow approach for the resection of a tuberculum sellae meningioma with intraoperative endoscopic assistance. ⁶²	Revuelta Barbero JM...Pradilla G	35399897	2022
15	Surgical management of tuberculum sellae meningioma: Transcranial approach or endoscopic endonasal approach? ⁶²	Qian K...Jiang X	36117830	2022
16	Keyhole supraorbital eyebrow approach for fully endoscopic resection of tuberculum sellae meningioma. ⁶²	Zheng X...Jiang Z	36157417	2022
17	Endoscopic endonasal resection of coexisting pituitary adenoma and meningioma: Two cases' report and literature review. ⁶²	Bao YY...Hong T	33652068	2021
18	Surgical Management of Tuberculum Sellae Meningioma: Our Experience and Review of the Literature. ⁶²	Sankhla SK...Khan GM	34979648	2021
19	How I do it: endoscopic endonasal resection of tuberculum sellae meningioma. ⁶²	Wiedmann M...Dahlberg D	33665730	2021
20	A caroticocavernous fistula without vascular injury following endoscopic transsphenoidal excision of a tuberculum sellae meningioma-A case report. ⁶²	Ngui JZ...Liew DNS	34026157	2021
21	Sellar and parasellar lesions: multidisciplinary management. ⁶²	Emanuelli E...Denaro L	34060518	2021
22	Tuberculum sellae meningioma surgery: visual outcomes and surgical aspects of contralateral approach. ⁶²	Voznyak O...Hryniv N	32180047	2021
23	The expanded endoscopic endonasal approach for treatment of tuberculum sellae meningiomas in a series of 40 consecutive cases. ⁶²	Yu P...Wang Y	33654211	2021
24	The endoscope-assisted supraorbital "keyhole" approach for anterior skull base meningiomas: an updated meta-analysis. ⁶²	Khan DZ...Marcus HJ	32889640	2021
25	Keyhole Superior Interhemispheric Transfalcine Approach for Tuberculum Sellae Meningioma: Technical Nuances and Visual Outcomes. ⁶²	Wong AK...Wong RH	32891837	2021
26	Familial Tuberculum Sellae Meningiomas. ⁶²	Zhou P...Shao N	32858607	2021
27	Supraorbital transciliary keyhole approach for removal of tuberculum sellae meningioma: 3D surgical video. ⁶²	Cuellar-Hernandez JJ...Valadez-Rodriguez A	33500820	2021
28	Unilateral Subfrontal Approach for Giant Tuberculum Sellae Meningioma: Single Center Experience and Review of the Literature. ⁶²	Xiao F...Zheng X	34434897	2021
29	Extended approach or usage of nasoseptal flap is a risk factor for olfactory dysfunction after endoscopic anterior skullbase surgery: results from 928 patients in a single tertiary center. ⁶²	Seo MY...Hong SD	32662778	2020
30	Do Not Give Up on Ossified Tuberculum Sellae Meningioma - Vision Restored. ⁶²	Candanedo C...Attia M	33150113	2020
31	Limited utility of 5-ALA optical fluorescence in endoscopic endonasal skull base surgery: a multicenter retrospective study. ⁶²	Micko A...Schwartz TH	33126212	2020
32	Endoscopic Endonasal Approach for Resection of Tuberculum Sellae Meningioma: A Promising Surgical Approach. ⁶²	Zhang C...Wu Y	32371698	2020
33	Commentary: Expanded Endoscopic Endonasal Transtuberculum Approach for Tuberculum Sellae Meningioma: Operative Video With 360-Degree Fly-Through and Surgical Rehearsal in Virtual Reality: 2-Dimensional Operative Video. ⁶²	Strickland BA...Zada G	32243544	2020
34	Expanded Endoscopic Endonasal Transtuberculum Approach for Tuberculum Sellae Meningioma: Operative Video With 360-Degree Fly-Through and Surgical Rehearsal in Virtual Reality: 2-Dimensional Operative Video. ⁶²	Jean WC...Singh A	32047909	2020
35	Cushing's disease due to a pituitary adenoma as a component of collision tumor: A case report and review of the literature. ⁶²	Gezer E...Cabuk B	32423480	2020
36	[Unruptured Fronto-Orbital Artery Aneurysm Anomalously Originating from the Proximal Segment of the Anterior Cerebral Artery(A1)Concurrent with Tuberculum Sellae Meningioma:A Case Report]. ⁶²	Hayashi D...Nakamizo A	32434956	2020
37	How I do it: contralateral supraorbital approach for tuberculum sellae meningioma. ⁶²	Peto I...Dehdashti AR	31900657	2020
38	Endoscopic Endonasal Transsphenoidal Approach for Resection of Tuberculum Sella and Planum Sphenoidale Meningiomas: A Snapshot of Our Institutional Experience. ⁶²	Salek MAA...Islam MA	32181168	2020
39	Transpalpebral Approach for Microsurgical Removal of Tuberculum Sellae Meningiomas. ⁶²	Dzhindzhikhadze RS...Salyamova EI	32181181	2020
40	Multidisciplinary team efforts improve the surgical outcomes of sellar region lesions during pregnancy. ⁶²	Zhong HP...Wu ZB	31422527	2019
41	Use of the Neurological Pupil Index to Predict Postoperative Visual Function After Resection of a Tuberculum Sellae Meningioma: A Case Report. ⁶²	Raygor KP...Theodosopoulos PV	31807386	2019
42	Combined Multiportal Endoscopic Endonasal and Transcranial Approach for Recurrent Tuberculum Sellae Meningioma: Operative Video. ⁶²	Restelli F...Locatelli D	30974272	2019
43	Tuberculum sellae meningioma with possible tacrolimus neurotoxicity manifesting as manic-like psychosis after kidney transplantation. ⁶²	Seo EH...Yoon HJ	31507644	2019
44	Recurrence of Anterior Skull Base Meningiomas After Endoscopic Endonasal Resection: 10 Years' Experience in a Series of 52 Endoscopic and Transcranial Cases. ⁶²	Bernat AL...Gentili F	30077030	2018
45	Olfactory groove and tuberculum sellae meningioma resection by endoscopic endonasal approach versus transcranial approach: A systematic review and meta-analysis of comparative studies. ⁶²	Lu VM...Rovin RA	30193170	2018
46	Contralateral Transcranial Approach to Tuberculum Sellae Meningiomas: Long-Term Visual Outcomes and Recurrence Rates. ⁶²	Engelhardt J...Loiseau H	29864568	2018
47	Letter to the Editor. Transcranial versus endonasal approaches in tuberculum sellae meningioma surgery. ⁶²	Marx S...Schroeder HWS	29799339	2018
48	[Spontaneous Improvement in Visual Symptom after Delivery in a Case of Tuberculum Sellae Meningioma]. ⁶²	Sakatsume S...Kinouchi H	30049902	2018
49	[Microsurgical resection of sellar tumors via lateral supraorbital approach: clinical analysis of 20 cases]. ⁶²	Lu XY...Wang L	29925170	2018
50	Utility of 3-Dimensional-Printed Models in Enhancing the Learning Curve of Surgery of Tuberculum Sellae Meningioma. ⁶²	Lin QS...Kang DZ	29432945	2018

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Genes for Tuberculum Sellae Meningioma

Genes related to Tuberculum Sellae Meningioma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	POMC	Proopiomelanocortin	Protein Coding	5.26	DISEASES inferred ¹⁴
2	MCCC1	Methylcrotonyl-CoA Carboxylase Subunit 1	Protein Coding	5.22	DISEASES inferred ¹⁴
3	MTO1	Mitochondrial TRNA Translation Optimization 1	Protein Coding	4.97	DISEASES inferred ¹⁴
4	NF2	NF2, Moesin-Ezrin-Radixin Like (MERLIN) Tumor Suppressor	Protein Coding	4.62	DISEASES inferred ¹⁴
5	TRAF7	TNF Receptor Associated Factor 7	Protein Coding	4.62	DISEASES inferred ¹⁴
6	PRL	Prolactin	Protein Coding	4.51	DISEASES inferred ¹⁴
7	EPB41L2	Erythrocyte Membrane Protein Band 4.1 Like 2	Protein Coding	4.16	DISEASES inferred ¹⁴
8	GHRH	Growth Hormone Releasing Hormone	Protein Coding	4	DISEASES inferred ¹⁴
9	EPB41	Erythrocyte Membrane Protein Band 4.1	Protein Coding	4	DISEASES inferred ¹⁴

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Variations for Tuberculum Sellae Meningioma

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Expression for Tuberculum Sellae Meningioma

Search GEO for disease gene expression data for Tuberculum Sellae Meningioma.

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Pathways for Tuberculum Sellae Meningioma

Pathways related to Tuberculum Sellae Meningioma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Prader-Willi and Angelman syndrome ⁷⁴	10.93	POMC GHRH
2	Splicing factor NOVA regulated synaptic proteins ⁷⁴	10.55	EPB41L2 EPB41
3	Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics ⁶⁰	9.92	PRL POMC

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GO Terms for Tuberculum Sellae Meningioma

Biological processes related to Tuberculum Sellae Meningioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	actomyosin structure organization	GO:0031032	9.46	EPB41L2 EPB41
2	cortical actin cytoskeleton organization	GO:0030866	9.26	EPB41L2 EPB41
3	positive regulation of protein localization to cell cortex	GO:1904778	8.92	EPB41L2 EPB41

Molecular functions related to Tuberculum Sellae Meningioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	spectrin binding	GO:0030507	9.46	EPB41L2 EPB41
2	hormone activity	GO:0005179	9.35	PRL POMC GHRH
3	cytoskeletal protein binding	GO:0008092	8.8	NF2 EPB41L2 EPB41

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Sources for Tuberculum Sellae Meningioma

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: TBR007 MIFTS: 29	Tuberculum Sellae Meningioma Categories: Bone diseases, Cancer diseases	Data Licensing For inquiries, contact: [email protected]
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