MCID: TBR007
MIFTS: 29

Tuberculum Sellae Meningioma

Categories: Bone diseases, Cancer diseases
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Aliases & Classifications for Tuberculum Sellae Meningioma

MalaCards integrated aliases for Tuberculum Sellae Meningioma:

Name: Tuberculum Sellae Meningioma 11 14 71
Meningioma of the Tuberculum Sellae 11

Classifications:



External Ids:

Disease Ontology 11 DOID:7713
NCIt 49 C5284
UMLS 71 C1336829

Summaries for Tuberculum Sellae Meningioma

MalaCards based summary: Tuberculum Sellae Meningioma, also known as meningioma of the tuberculum sellae, is related to meningioma, familial and abducens palsy, and has symptoms including headache and seizures. An important gene associated with Tuberculum Sellae Meningioma is POMC (Proopiomelanocortin), and among its related pathways/superpathways are Prader-Willi and Angelman syndrome and Splicing factor NOVA regulated synaptic proteins. Affiliated tissues include bone, pituitary and caudate nucleus, and related phenotype is liver/biliary system.

Related Diseases for Tuberculum Sellae Meningioma

Diseases related to Tuberculum Sellae Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 131)
# Related Disease Score Top Affiliating Genes
1 meningioma, familial 30.9 TRAF7 PRL POMC NF2 EPB41
2 abducens palsy 30.5 PRL POMC
3 olfactory groove meningioma 30.5 TRAF7 NF2
4 angiomatous meningioma 30.5 TRAF7 NF2
5 skull base meningioma 30.5 TRAF7 NF2
6 central diabetes insipidus 30.4 PRL POMC
7 pituitary adenoma 30.4 PRL POMC GHRH
8 adenoma 30.3 PRL POMC GHRH
9 pituitary hormone deficiency, combined, 2 29.9 PRL POMC GHRH
10 cerebrospinal fluid leak 10.6
11 3-methylglutaconic aciduria, type iii 10.5
12 vascular disease 10.4
13 pituitary tumors 10.4
14 prostate cancer 10.2
15 hypothyroidism, congenital, nongoitrous, 2 10.2
16 moyamoya disease 1 10.2
17 thyrotropin-releasing hormone deficiency 10.2
18 lymphoproliferative syndrome, x-linked, 1 10.2
19 hypothyroidism, congenital, nongoitrous, 3 10.2
20 ptosis 10.2
21 uveitis 10.2
22 optic nerve disease 10.2
23 hyperostosis 10.2
24 psychotic disorder 10.2
25 gastric antral vascular ectasia 10.2
26 hemangioma 10.2
27 toxic encephalopathy 10.2
28 neuropathy 10.2
29 diabetes insipidus 10.2
30 bacterial meningitis 10.2
31 suprasellar meningioma 10.2 POMC NF2
32 chiasmal syndrome 10.1 PRL POMC
33 cranial nerve malignant neoplasm 10.1 POMC NF2
34 prolactin producing pituitary tumor 10.1 PRL POMC
35 sphenoorbital meningioma 10.1 TRAF7 NF2
36 foramen magnum meningioma 10.1 TRAF7 NF2
37 acidophil adenoma 10.1 PRL POMC
38 chromophobe adenoma 10.1 PRL POMC
39 ectopic cushing syndrome 10.1 PRL POMC
40 childhood meningioma 10.1 TRAF7 NF2
41 cavernous sinus meningioma 10.1 TRAF7 NF2
42 cerebral falx meningioma 10.1 TRAF7 NF2
43 psammomatous meningioma 10.1 TRAF7 NF2
44 parasagittal meningioma 10.1 TRAF7 NF2
45 tsh producing pituitary tumor 10.1 PRL POMC
46 microcystic meningioma 10.1 TRAF7 NF2
47 intraventricular meningioma 10.1 TRAF7 NF2
48 cerebral convexity meningioma 10.1 TRAF7 NF2
49 optic nerve sheath meningioma 10.1 TRAF7 NF2
50 sheehan syndrome 10.1 PRL POMC

Graphical network of the top 20 diseases related to Tuberculum Sellae Meningioma:



Diseases related to Tuberculum Sellae Meningioma

Symptoms & Phenotypes for Tuberculum Sellae Meningioma

UMLS symptoms related to Tuberculum Sellae Meningioma:


headache; seizures

MGI Mouse Phenotypes related to Tuberculum Sellae Meningioma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 liver/biliary system MP:0005370 9.02 EPB41 GHRH NF2 POMC PRL

Drugs & Therapeutics for Tuberculum Sellae Meningioma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Paraoptic Tumors : Study of the Radiological, Ophthalmological and Intraoperative Predictive Factors of Visual Recovery After Neurosurgical Removal Recruiting NCT03567486

Search NIH Clinical Center for Tuberculum Sellae Meningioma

Genetic Tests for Tuberculum Sellae Meningioma

Anatomical Context for Tuberculum Sellae Meningioma

Organs/tissues related to Tuberculum Sellae Meningioma:

MalaCards : Bone, Pituitary, Caudate Nucleus, Brain, Prostate, Kidney

Publications for Tuberculum Sellae Meningioma

Articles related to Tuberculum Sellae Meningioma:

(show top 50) (show all 186)
# Title Authors PMID Year
1
Treatment of Intracranial Tumors With Stereotactic Radiosurgery: Short-Term Results From Cuba. 62
36348852 2022
2
Does Endoscopic Transnasal Optic Nerve Decompression Followed by Radiosurgery Improve Outcomes in the Treatment of Parasellar Meningiomas? 62
36013604 2022
3
Microsurgical Resection of Tuberculum Sellae Meningioma through Pterional Approach with Extradural Optic Canal Unroofing. 62
36068909 2022
4
Predictive Factors of Favorable Visual Outcomes After Surgery of Tuberculum Sellae Meningiomas: A Multicenter Retrospective Cohort Study. 62
35568126 2022
5
Contralateral subfrontal approach for tuberculum sellae meningioma: techniques and clinical outcomes. 62
35901684 2022
6
Optical coherence tomography as a useful adjunct in the early detection of meningioma with optic nerve compression. 62
36248089 2022
7
Management of Internal Carotid Artery Injury During Transsphenoidal Surgery: A Case Series and Suggestion for Optimal Management. 62
35364296 2022
8
How I do it: optic canal unroofing in surgery for tuberculum sellae meningiomas with compression of the optic nerve. 62
35094145 2022
9
Modified Shoelace Dural Closure with Collagen Matrix in Extended Transsphenoidal Surgery. 62
35296586 2022
10
Skull Base Approaches for Tuberculum Sellae Meningiomas: Institutional Experience in a Series of 34 Patients. 62
35454983 2022
11
Dural metastasis from prostate carcinoma mimicking tuberculum sellae meningioma: A case report. 62
36324921 2022
12
Comparison of the Efficacy and Safety of Neuroendoscopic Endonasal Transsphenoidal Surgeries and Intracranial Endoscopic Pterional Approach in Resection of Tuberculum Sellae Meningiomas. 62
35711498 2022
13
Improvement of optic nerve pial blood supply visualized through indocyanine green videoangiography after resection of a tuberculum sellae meningioma: 2-dimensional operative video. 62
36284583 2022
14
Keyhole supraorbital eyebrow approach for the resection of a tuberculum sellae meningioma with intraoperative endoscopic assistance. 62
35399897 2022
15
Surgical management of tuberculum sellae meningioma: Transcranial approach or endoscopic endonasal approach? 62
36117830 2022
16
Keyhole supraorbital eyebrow approach for fully endoscopic resection of tuberculum sellae meningioma. 62
36157417 2022
17
Endoscopic endonasal resection of coexisting pituitary adenoma and meningioma: Two cases' report and literature review. 62
33652068 2021
18
Surgical Management of Tuberculum Sellae Meningioma: Our Experience and Review of the Literature. 62
34979648 2021
19
How I do it: endoscopic endonasal resection of tuberculum sellae meningioma. 62
33665730 2021
20
A caroticocavernous fistula without vascular injury following endoscopic transsphenoidal excision of a tuberculum sellae meningioma-A case report. 62
34026157 2021
21
Sellar and parasellar lesions: multidisciplinary management. 62
34060518 2021
22
Tuberculum sellae meningioma surgery: visual outcomes and surgical aspects of contralateral approach. 62
32180047 2021
23
The expanded endoscopic endonasal approach for treatment of tuberculum sellae meningiomas in a series of 40 consecutive cases. 62
33654211 2021
24
The endoscope-assisted supraorbital "keyhole" approach for anterior skull base meningiomas: an updated meta-analysis. 62
32889640 2021
25
Keyhole Superior Interhemispheric Transfalcine Approach for Tuberculum Sellae Meningioma: Technical Nuances and Visual Outcomes. 62
32891837 2021
26
Familial Tuberculum Sellae Meningiomas. 62
32858607 2021
27
Supraorbital transciliary keyhole approach for removal of tuberculum sellae meningioma: 3D surgical video. 62
33500820 2021
28
Unilateral Subfrontal Approach for Giant Tuberculum Sellae Meningioma: Single Center Experience and Review of the Literature. 62
34434897 2021
29
Extended approach or usage of nasoseptal flap is a risk factor for olfactory dysfunction after endoscopic anterior skullbase surgery: results from 928 patients in a single tertiary center. 62
32662778 2020
30
Do Not Give Up on Ossified Tuberculum Sellae Meningioma - Vision Restored. 62
33150113 2020
31
Limited utility of 5-ALA optical fluorescence in endoscopic endonasal skull base surgery: a multicenter retrospective study. 62
33126212 2020
32
Endoscopic Endonasal Approach for Resection of Tuberculum Sellae Meningioma: A Promising Surgical Approach. 62
32371698 2020
33
Commentary: Expanded Endoscopic Endonasal Transtuberculum Approach for Tuberculum Sellae Meningioma: Operative Video With 360-Degree Fly-Through and Surgical Rehearsal in Virtual Reality: 2-Dimensional Operative Video. 62
32243544 2020
34
Expanded Endoscopic Endonasal Transtuberculum Approach for Tuberculum Sellae Meningioma: Operative Video With 360-Degree Fly-Through and Surgical Rehearsal in Virtual Reality: 2-Dimensional Operative Video. 62
32047909 2020
35
Cushing's disease due to a pituitary adenoma as a component of collision tumor: A case report and review of the literature. 62
32423480 2020
36
[Unruptured Fronto-Orbital Artery Aneurysm Anomalously Originating from the Proximal Segment of the Anterior Cerebral Artery(A1)Concurrent with Tuberculum Sellae Meningioma:A Case Report]. 62
32434956 2020
37
How I do it: contralateral supraorbital approach for tuberculum sellae meningioma. 62
31900657 2020
38
Endoscopic Endonasal Transsphenoidal Approach for Resection of Tuberculum Sella and Planum Sphenoidale Meningiomas: A Snapshot of Our Institutional Experience. 62
32181168 2020
39
Transpalpebral Approach for Microsurgical Removal of Tuberculum Sellae Meningiomas. 62
32181181 2020
40
Multidisciplinary team efforts improve the surgical outcomes of sellar region lesions during pregnancy. 62
31422527 2019
41
Use of the Neurological Pupil Index to Predict Postoperative Visual Function After Resection of a Tuberculum Sellae Meningioma: A Case Report. 62
31807386 2019
42
Combined Multiportal Endoscopic Endonasal and Transcranial Approach for Recurrent Tuberculum Sellae Meningioma: Operative Video. 62
30974272 2019
43
Tuberculum sellae meningioma with possible tacrolimus neurotoxicity manifesting as manic-like psychosis after kidney transplantation. 62
31507644 2019
44
Recurrence of Anterior Skull Base Meningiomas After Endoscopic Endonasal Resection: 10 Years' Experience in a Series of 52 Endoscopic and Transcranial Cases. 62
30077030 2018
45
Olfactory groove and tuberculum sellae meningioma resection by endoscopic endonasal approach versus transcranial approach: A systematic review and meta-analysis of comparative studies. 62
30193170 2018
46
Contralateral Transcranial Approach to Tuberculum Sellae Meningiomas: Long-Term Visual Outcomes and Recurrence Rates. 62
29864568 2018
47
Letter to the Editor. Transcranial versus endonasal approaches in tuberculum sellae meningioma surgery. 62
29799339 2018
48
[Spontaneous Improvement in Visual Symptom after Delivery in a Case of Tuberculum Sellae Meningioma]. 62
30049902 2018
49
[Microsurgical resection of sellar tumors via lateral supraorbital approach: clinical analysis of 20 cases]. 62
29925170 2018
50
Utility of 3-Dimensional-Printed Models in Enhancing the Learning Curve of Surgery of Tuberculum Sellae Meningioma. 62
29432945 2018

Variations for Tuberculum Sellae Meningioma

Expression for Tuberculum Sellae Meningioma

Search GEO for disease gene expression data for Tuberculum Sellae Meningioma.

Pathways for Tuberculum Sellae Meningioma

Pathways related to Tuberculum Sellae Meningioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.93 POMC GHRH
2 10.55 EPB41L2 EPB41
3 9.92 PRL POMC

GO Terms for Tuberculum Sellae Meningioma

Biological processes related to Tuberculum Sellae Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 actomyosin structure organization GO:0031032 9.46 EPB41L2 EPB41
2 cortical actin cytoskeleton organization GO:0030866 9.26 EPB41L2 EPB41
3 positive regulation of protein localization to cell cortex GO:1904778 8.92 EPB41L2 EPB41

Molecular functions related to Tuberculum Sellae Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 spectrin binding GO:0030507 9.46 EPB41L2 EPB41
2 hormone activity GO:0005179 9.35 PRL POMC GHRH
3 cytoskeletal protein binding GO:0008092 8.8 NF2 EPB41L2 EPB41

Sources for Tuberculum Sellae Meningioma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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