TSG11
MCID: TMR016
MIFTS: 28

Tumor Suppressor Gene on Chromosome 11 (TSG11)

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Tumor Suppressor Gene on Chromosome 11

MalaCards integrated aliases for Tumor Suppressor Gene on Chromosome 11:

Name: Tumor Suppressor Gene on Chromosome 11 57 13 73
Nonsmall Cell Lung Cancer Suppressor 57
Non-Small Cell Lung Carcinoma 73
Nonsmall Cell Lung Cancer 57
Tsg11 57

Classifications:



External Ids:

OMIM 57 603040

Summaries for Tumor Suppressor Gene on Chromosome 11

MalaCards based summary : Tumor Suppressor Gene on Chromosome 11, also known as nonsmall cell lung cancer suppressor, is related to lung cancer and lymphoma. An important gene associated with Tumor Suppressor Gene on Chromosome 11 is TSG11 (Tumor Suppressor Gene On Chromosome 11). The drug Opdivo has been mentioned in the context of this disorder. Affiliated tissues include lung, testes and prostate.

Description from OMIM: 603040

Related Diseases for Tumor Suppressor Gene on Chromosome 11

Diseases related to Tumor Suppressor Gene on Chromosome 11 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 31)
# Related Disease Score Top Affiliating Genes
1 lung cancer 12.5
2 lymphoma 10.4
3 retinoblastoma 10.2
4 squamous cell carcinoma 10.2
5 bladder cancer 10.0
6 glioma susceptibility 1 10.0
7 ataxia-telangiectasia 10.0
8 squamous cell carcinoma, head and neck 10.0
9 xeroderma pigmentosum, variant type 10.0
10 alzheimer disease 5 10.0
11 thrombocytopenia 10.0
12 large cell neuroendocrine carcinoma 10.0
13 colitis 10.0
14 ischemic colitis 10.0
15 mucositis 10.0
16 heart disease 10.0
17 conn's syndrome 10.0
18 patulous eustachian tube 10.0
19 melanoma 10.0
20 hypogonadism 10.0
21 pharyngitis 10.0
22 glioblastoma multiforme 10.0
23 interstitial lung disease 10.0
24 myelitis 10.0
25 thymus cancer 10.0
26 peripheral nervous system disease 10.0
27 lung disease 10.0
28 neuropathy 10.0
29 glioblastoma 10.0
30 hypoxia 10.0
31 radiation myelitis 10.0

Graphical network of the top 20 diseases related to Tumor Suppressor Gene on Chromosome 11:



Diseases related to Tumor Suppressor Gene on Chromosome 11

Symptoms & Phenotypes for Tumor Suppressor Gene on Chromosome 11

Clinical features from OMIM:

603040

Drugs & Therapeutics for Tumor Suppressor Gene on Chromosome 11

FDA approved drugs:

# Drug Name Active Ingredient(s) 18 Company Approval Date
1
Opdivo 18 NIVOLUMAB Bristol-Myers Squibb March 2015

Search Clinical Trials , NIH Clinical Center for Tumor Suppressor Gene on Chromosome 11

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Genetic Tests for Tumor Suppressor Gene on Chromosome 11

Anatomical Context for Tumor Suppressor Gene on Chromosome 11

MalaCards organs/tissues related to Tumor Suppressor Gene on Chromosome 11:

41
Lung, Testes, Prostate, Brain, Kidney, Bone, Thymus

Publications for Tumor Suppressor Gene on Chromosome 11

Articles related to Tumor Suppressor Gene on Chromosome 11:

# Title Authors Year
1
Allelotyping in Wilms tumors identifies a putative third tumor suppressor gene on chromosome 11. ( 7558032 )
1995
2
Putative tumor-suppressor gene on chromosome 11 is important in sporadic endocrine tumor formation. ( 7906100 )
1994

Variations for Tumor Suppressor Gene on Chromosome 11

Expression for Tumor Suppressor Gene on Chromosome 11

Search GEO for disease gene expression data for Tumor Suppressor Gene on Chromosome 11.

Pathways for Tumor Suppressor Gene on Chromosome 11

GO Terms for Tumor Suppressor Gene on Chromosome 11

Sources for Tumor Suppressor Gene on Chromosome 11

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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