MCID: TYP027
MIFTS: 20

Type 1 Diabetes Mellitus 10

Categories: Metabolic diseases, Endocrine diseases

Aliases & Classifications for Type 1 Diabetes Mellitus 10

MalaCards integrated aliases for Type 1 Diabetes Mellitus 10:

Name: Type 1 Diabetes Mellitus 10 12 15
Diabetes Mellitus, Insulin-Dependent, 10 73
Insulin-Dependent Diabetes Mellitus 10 12
Iddm10 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0110749
ICD10 33 E10
UMLS 73 C1866040

Summaries for Type 1 Diabetes Mellitus 10

Disease Ontology : 12 A type 1 diabetes mellitus that has material basis in mutation of the IL2RA gene on chromosome 10p15.1.

MalaCards based summary : Type 1 Diabetes Mellitus 10, also known as diabetes mellitus, insulin-dependent, 10, is related to diabetes mellitus, insulin-dependent, 10 and congenital aphakia. An important gene associated with Type 1 Diabetes Mellitus 10 is MTPAP (Mitochondrial Poly(A) Polymerase), and among its related pathways/superpathways are Immune response IFN gamma signaling pathway and Rheumatoid arthritis.

Related Diseases for Type 1 Diabetes Mellitus 10

Graphical network of the top 20 diseases related to Type 1 Diabetes Mellitus 10:



Diseases related to Type 1 Diabetes Mellitus 10

Symptoms & Phenotypes for Type 1 Diabetes Mellitus 10

Drugs & Therapeutics for Type 1 Diabetes Mellitus 10

Search Clinical Trials , NIH Clinical Center for Type 1 Diabetes Mellitus 10

Genetic Tests for Type 1 Diabetes Mellitus 10

Anatomical Context for Type 1 Diabetes Mellitus 10

Publications for Type 1 Diabetes Mellitus 10

Articles related to Type 1 Diabetes Mellitus 10:

# Title Authors Year
1
Prolonged effect of intensive therapy on the risk of retinopathy complications in patients with type 1 diabetes mellitus: 10 years after the Diabetes Control and Complications Trial. ( 19064853 )
2008

Variations for Type 1 Diabetes Mellitus 10

Expression for Type 1 Diabetes Mellitus 10

Search GEO for disease gene expression data for Type 1 Diabetes Mellitus 10.

Pathways for Type 1 Diabetes Mellitus 10

Pathways related to Type 1 Diabetes Mellitus 10 according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.27 CXCL12 IL16 IL17A TNFRSF10A
2 10.75 CTLA4 CXCL12 IL17A
3 10.65 CAT SOD2

GO Terms for Type 1 Diabetes Mellitus 10

Biological processes related to Type 1 Diabetes Mellitus 10 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to hypoxia GO:0001666 9.43 CAT CXCL12 HMOX2
2 regulation of calcium ion transport GO:0051924 9.16 CXCL12 IL16
3 immune response GO:0006955 9.02 CTLA4 CXCL12 IL16 IL17A TNFRSF10A
4 induction of positive chemotaxis GO:0050930 8.96 CXCL12 IL16

Sources for Type 1 Diabetes Mellitus 10

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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