MCID: TYP036
MIFTS: 23

Type 1 Diabetes Mellitus 12

Categories: Blood diseases, Endocrine diseases, Genetic diseases, Metabolic diseases

Aliases & Classifications for Type 1 Diabetes Mellitus 12

MalaCards integrated aliases for Type 1 Diabetes Mellitus 12:

Name: Type 1 Diabetes Mellitus 12 12 15
Diabetes Mellitus, Insulin-Dependent, 12 74
Insulin-Dependent Diabetes Mellitus 12 12
Iddm12 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0110751
ICD10 34 E10
UMLS 74 C1832392

Summaries for Type 1 Diabetes Mellitus 12

Disease Ontology : 12 A type 1 diabetes mellitus that has material basis in mutation of the CTLA4 gene on chromosome 2q33.2.

MalaCards based summary : Type 1 Diabetes Mellitus 12, also known as diabetes mellitus, insulin-dependent, 12, is related to graves' disease and diabetes mellitus. An important gene associated with Type 1 Diabetes Mellitus 12 is CTLA4 (Cytotoxic T-Lymphocyte Associated Protein 4), and among its related pathways/superpathways are Innate Immune System and Class I MHC mediated antigen processing and presentation.

Related Diseases for Type 1 Diabetes Mellitus 12

Diseases in the Diabetes Mellitus family:

Diabetes Mellitus, Congenital Autoimmune Type 1 Diabetes Mellitus 2
Type 1 Diabetes Mellitus 3 Type 1 Diabetes Mellitus 4
Type 1 Diabetes Mellitus 5 Type 1 Diabetes Mellitus 6
Type 1 Diabetes Mellitus 7 Type 1 Diabetes Mellitus 8
Type 1 Diabetes Mellitus 10 Type 1 Diabetes Mellitus 11
Type 1 Diabetes Mellitus 12 Type 1 Diabetes Mellitus 13
Type 1 Diabetes Mellitus 15 Type 1 Diabetes Mellitus 17
Type 1 Diabetes Mellitus 18

Diseases related to Type 1 Diabetes Mellitus 12 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 28)
# Related Disease Score Top Affiliating Genes
1 graves' disease 29.7 CTLA4 HLA-DRB1
2 diabetes mellitus 28.9 CTLA4 HLA-DRB1 INS SUMO4
3 diabetes mellitus, insulin-dependent 28.9 CTLA4 HLA-DRB1 INS SUMO4
4 diabetes mellitus, insulin-dependent, 12 11.3
5 thyroiditis 10.1
6 type 1 diabetes mellitus 11 10.1 CTLA4 INS
7 type 1 diabetes mellitus 2 10.1 FGF3 INS
8 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.1 CTLA4 INS
9 autoimmune addison disease 10.1 CTLA4 HLA-DRB1
10 autoimmune disease of endocrine system 10.0 CTLA4 INS
11 type 1 diabetes mellitus 7 10.0 INS SLC11A1
12 anca-associated vasculitis 10.0 CTLA4 HLA-DRB1
13 pemphigus foliaceus 10.0 CTLA4 HLA-DRB1
14 sympathetic ophthalmia 10.0 CTLA4 HLA-DRB1
15 rheumatoid factor-negative juvenile idiopathic arthritis 10.0 HLA-DRB1 SLC11A1
16 autoimmune pancreatitis 10.0 CTLA4 HLA-DRB1
17 hirata disease 10.0 HLA-DRB1 INS
18 hyperthyroidism 10.0 CTLA4 INS
19 nontuberculous mycobacterial lung disease 9.9 HLA-DRB1 SLC11A1
20 autoimmune hepatitis 9.9 CTLA4 HLA-DRB1
21 juvenile rheumatoid arthritis 9.9 HLA-DRB1 SLC11A1
22 pulmonary tuberculosis 9.8 HLA-DRB1 SLC11A1
23 type 1 diabetes mellitus 13 9.8 CTLA4 INS SLC11A1
24 sarcoidosis 1 9.8 HLA-DRB1 SLC11A1
25 autoimmune disease 9.7 CTLA4 HLA-DRB1 INS
26 leishmaniasis 9.7 HLA-DRB1 SLC11A1
27 rheumatoid arthritis 9.7 CTLA4 HLA-DRB1 SLC11A1
28 type 1 diabetes mellitus 5 9.4 CTLA4 FGF3 INS SUMO4

Graphical network of the top 20 diseases related to Type 1 Diabetes Mellitus 12:



Diseases related to Type 1 Diabetes Mellitus 12

Symptoms & Phenotypes for Type 1 Diabetes Mellitus 12

Drugs & Therapeutics for Type 1 Diabetes Mellitus 12

Search Clinical Trials , NIH Clinical Center for Type 1 Diabetes Mellitus 12

Genetic Tests for Type 1 Diabetes Mellitus 12

Anatomical Context for Type 1 Diabetes Mellitus 12

Publications for Type 1 Diabetes Mellitus 12

Articles related to Type 1 Diabetes Mellitus 12:

# Title Authors Year
1
Twice- rather than once-daily basal insulin is associated with better glycaemic control in Type 1 diabetes mellitus 12 months after skills-based structured education in insulin self-management. ( 25982032 )
2015

Variations for Type 1 Diabetes Mellitus 12

Expression for Type 1 Diabetes Mellitus 12

Search GEO for disease gene expression data for Type 1 Diabetes Mellitus 12.

Pathways for Type 1 Diabetes Mellitus 12

GO Terms for Type 1 Diabetes Mellitus 12

Cellular components related to Type 1 Diabetes Mellitus 12 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 late endosome membrane GO:0031902 8.62 HLA-DRB1 SLC11A1

Biological processes related to Type 1 Diabetes Mellitus 12 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 wound healing GO:0042060 9.16 INS SLC11A1
2 immune response GO:0006955 9.13 CTLA4 HLA-DRB1 SLC11A1
3 negative regulation of T cell proliferation GO:0042130 8.62 CTLA4 HLA-DRB1

Sources for Type 1 Diabetes Mellitus 12

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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