MCID: TYP038
MIFTS: 22

Type 1 Diabetes Mellitus 15

Categories: Metabolic diseases, Endocrine diseases

Aliases & Classifications for Type 1 Diabetes Mellitus 15

MalaCards integrated aliases for Type 1 Diabetes Mellitus 15:

Name: Type 1 Diabetes Mellitus 15 12 15
Diabetes Mellitus, Insulin-Dependent, 15 73
Insulin-Dependent Diabetes Mellitus 15 12
Iddm15 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0110753
ICD10 33 E10
UMLS 73 C1866519

Summaries for Type 1 Diabetes Mellitus 15

Disease Ontology : 12 A type 1 diabetes mellitus that has material basis in mutation of the locus at chromosome 6q21.

MalaCards based summary : Type 1 Diabetes Mellitus 15, also known as diabetes mellitus, insulin-dependent, 15, is related to diabetes mellitus, insulin-dependent and diabetes mellitus. An important gene associated with Type 1 Diabetes Mellitus 15 is PIK3CG (Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma), and among its related pathways/superpathways are PI3K-Akt signaling pathway and Common Cytokine Receptor Gamma-Chain Family Signaling Pathways.

Related Diseases for Type 1 Diabetes Mellitus 15

Graphical network of the top 20 diseases related to Type 1 Diabetes Mellitus 15:



Diseases related to Type 1 Diabetes Mellitus 15

Symptoms & Phenotypes for Type 1 Diabetes Mellitus 15

Drugs & Therapeutics for Type 1 Diabetes Mellitus 15

Search Clinical Trials , NIH Clinical Center for Type 1 Diabetes Mellitus 15

Genetic Tests for Type 1 Diabetes Mellitus 15

Anatomical Context for Type 1 Diabetes Mellitus 15

Publications for Type 1 Diabetes Mellitus 15

Variations for Type 1 Diabetes Mellitus 15

Expression for Type 1 Diabetes Mellitus 15

Search GEO for disease gene expression data for Type 1 Diabetes Mellitus 15.

Pathways for Type 1 Diabetes Mellitus 15

Pathways related to Type 1 Diabetes Mellitus 15 according to GeneCards Suite gene sharing:

(show all 24)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.59 HRAS INS PIK3CG
2
Show member pathways
12.48 HRAS INS PIK3CG
3
Show member pathways
12.33 HRAS INS PIK3CG
4 12.19 HRAS INS PIK3CG
5
Show member pathways
12.06 HRAS INS PIK3CG
6
Show member pathways
12.01 HRAS INS PIK3CG
7
Show member pathways
11.88 HRAS INS PIK3CG
8
Show member pathways
11.79 GCG HRAS INS PIK3CG
9
Show member pathways
11.76 HRAS INS
10 11.75 HRAS PIK3CG
11
Show member pathways
11.75 HRAS INS PIK3CG
12
Show member pathways
11.73 HRAS PIK3CG
13 11.71 HRAS INS
14 11.65 HRAS PIK3CG
15 11.6 HRAS INS
16
Show member pathways
11.54 HRAS PIK3CG
17
Show member pathways
11.53 INS PIK3CG
18
Show member pathways
11.52 HRAS INS PIK3CG
19
Show member pathways
11.44 HRAS PIK3CG
20
Show member pathways
11.16 GCG INS
21 11.11 HRAS INS
22 10.98 HRAS INS
23 10.96 HRAS PIK3CG
24 10.8 HRAS PIK3CG

GO Terms for Type 1 Diabetes Mellitus 15

Cellular components related to Type 1 Diabetes Mellitus 15 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 secretory granule lumen GO:0034774 8.62 GCG INS

Biological processes related to Type 1 Diabetes Mellitus 15 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 animal organ morphogenesis GO:0009887 9.16 HCCS HRAS
2 positive regulation of MAP kinase activity GO:0043406 8.96 HRAS PIK3CG
3 positive regulation of DNA replication GO:0045740 8.62 HRAS INS

Molecular functions related to Type 1 Diabetes Mellitus 15 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.62 GCG INS

Sources for Type 1 Diabetes Mellitus 15

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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