MCID: TYP039
MIFTS: 19

Type 1 Diabetes Mellitus 17

Categories: Blood diseases, Endocrine diseases, Genetic diseases, Metabolic diseases

Aliases & Classifications for Type 1 Diabetes Mellitus 17

MalaCards integrated aliases for Type 1 Diabetes Mellitus 17:

Name: Type 1 Diabetes Mellitus 17 12 15
Diabetes Mellitus, Insulin-Dependent, 17 74
Insulin-Dependent Diabetes Mellitus 17 12
Iddm17 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0110754
ICD10 34 E10
UMLS 74 C1864068

Summaries for Type 1 Diabetes Mellitus 17

Disease Ontology : 12 A type 1 diabetes mellitus that has material basis in mutation of the locus at chromosome 10q25.

MalaCards based summary : Type 1 Diabetes Mellitus 17, also known as diabetes mellitus, insulin-dependent, 17, is related to diabetes mellitus, insulin-dependent, 17 and diabetes mellitus, insulin-dependent. An important gene associated with Type 1 Diabetes Mellitus 17 is CASP14 (Caspase 14), and among its related pathways/superpathways are Apoptosis and Autophagy and T Cell Co-Signaling Pathway: Ligand-Receptor Interactions.

Related Diseases for Type 1 Diabetes Mellitus 17

Diseases in the Diabetes Mellitus family:

Diabetes Mellitus, Congenital Autoimmune Type 1 Diabetes Mellitus 2
Type 1 Diabetes Mellitus 3 Type 1 Diabetes Mellitus 4
Type 1 Diabetes Mellitus 5 Type 1 Diabetes Mellitus 6
Type 1 Diabetes Mellitus 7 Type 1 Diabetes Mellitus 8
Type 1 Diabetes Mellitus 10 Type 1 Diabetes Mellitus 11
Type 1 Diabetes Mellitus 12 Type 1 Diabetes Mellitus 13
Type 1 Diabetes Mellitus 15 Type 1 Diabetes Mellitus 17
Type 1 Diabetes Mellitus 18

Diseases related to Type 1 Diabetes Mellitus 17 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 22)
# Related Disease Score Top Affiliating Genes
1 diabetes mellitus, insulin-dependent, 17 11.8
2 diabetes mellitus, insulin-dependent 11.1
3 perrault syndrome 1 11.1
4 adrenal cortical hypofunction 10.1 AIRE TNFRSF25
5 childhood type dermatomyositis 10.0 TNFRSF25 VWF
6 cholangitis, primary sclerosing 10.0 AIRE TNFRSF25
7 type 1 diabetes mellitus 11 9.9 CTLA4 TNFRSF25
8 autoimmune disease of gastrointestinal tract 9.9 CTLA4 TNFRSF25
9 autoimmune addison disease 9.9 AIRE CTLA4
10 immune system disease 9.9 TNFRSF25 VWF
11 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 9.8 AIRE CTLA4
12 vitiligo-associated multiple autoimmune disease susceptibility 1 9.8 AIRE CTLA4
13 celiac disease 1 9.8 CTLA4 TNFRSF25
14 hypoadrenocorticism, familial 9.8 AIRE CTLA4
15 alopecia areata 9.8 AIRE CTLA4
16 autoimmune hepatitis 9.8 AIRE CTLA4
17 myasthenia gravis 9.7 AIRE CTLA4
18 type 1 diabetes mellitus 5 9.6 AIRE CTLA4 TNFRSF25
19 autoimmune disease of endocrine system 9.6 AIRE CTLA4 TNFRSF25
20 thymoma 9.6 AIRE CTLA4
21 hashimoto thyroiditis 9.5 AIRE CTLA4
22 hypothyroidism 9.5 AIRE CTLA4 VWF

Graphical network of the top 20 diseases related to Type 1 Diabetes Mellitus 17:



Diseases related to Type 1 Diabetes Mellitus 17

Symptoms & Phenotypes for Type 1 Diabetes Mellitus 17

Drugs & Therapeutics for Type 1 Diabetes Mellitus 17

Search Clinical Trials , NIH Clinical Center for Type 1 Diabetes Mellitus 17

Genetic Tests for Type 1 Diabetes Mellitus 17

Anatomical Context for Type 1 Diabetes Mellitus 17

Publications for Type 1 Diabetes Mellitus 17

Variations for Type 1 Diabetes Mellitus 17

Expression for Type 1 Diabetes Mellitus 17

Search GEO for disease gene expression data for Type 1 Diabetes Mellitus 17.

Pathways for Type 1 Diabetes Mellitus 17

Pathways related to Type 1 Diabetes Mellitus 17 according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.07 CASP14 CASP7 TNFRSF25
2 10.72 CTLA4 TNFRSF25

GO Terms for Type 1 Diabetes Mellitus 17

Molecular functions related to Type 1 Diabetes Mellitus 17 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cysteine-type endopeptidase activity GO:0004197 8.96 CASP14 CASP7
2 cysteine-type endopeptidase activity involved in apoptotic process GO:0097153 8.62 CASP14 CASP7

Sources for Type 1 Diabetes Mellitus 17

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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