MCID: TYP039
MIFTS: 21

Type 1 Diabetes Mellitus 17

Categories: Blood diseases, Endocrine diseases, Genetic diseases, Metabolic diseases

Aliases & Classifications for Type 1 Diabetes Mellitus 17

MalaCards integrated aliases for Type 1 Diabetes Mellitus 17:

Name: Type 1 Diabetes Mellitus 17 12 15
Diabetes Mellitus, Insulin-Dependent, 17 73
Insulin-Dependent Diabetes Mellitus 17 12
Iddm17 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0110754
ICD10 33 E10
UMLS 73 C1864068

Summaries for Type 1 Diabetes Mellitus 17

Disease Ontology : 12 A type 1 diabetes mellitus that has material basis in mutation of the locus at chromosome 10q25.

MalaCards based summary : Type 1 Diabetes Mellitus 17, also known as diabetes mellitus, insulin-dependent, 17, is related to diabetes mellitus, insulin-dependent and diabetes mellitus, insulin-dependent, 17. An important gene associated with Type 1 Diabetes Mellitus 17 is CASP14 (Caspase 14), and among its related pathways/superpathways are Apoptosis and Autophagy and T Cell Co-Signaling Pathway: Ligand-Receptor Interactions. Affiliated tissues include thyroid and t cells.

Related Diseases for Type 1 Diabetes Mellitus 17

Diseases in the Diabetes Mellitus family:

Diabetes Mellitus, Congenital Autoimmune Type 1 Diabetes Mellitus 2
Type 1 Diabetes Mellitus 3 Type 1 Diabetes Mellitus 4
Type 1 Diabetes Mellitus 5 Type 1 Diabetes Mellitus 6
Type 1 Diabetes Mellitus 7 Type 1 Diabetes Mellitus 8
Type 1 Diabetes Mellitus 10 Type 1 Diabetes Mellitus 11
Type 1 Diabetes Mellitus 12 Type 1 Diabetes Mellitus 13
Type 1 Diabetes Mellitus 15 Type 1 Diabetes Mellitus 17
Type 1 Diabetes Mellitus 18

Diseases related to Type 1 Diabetes Mellitus 17 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 22)
# Related Disease Score Top Affiliating Genes
1 diabetes mellitus, insulin-dependent 31.3 AIRE CTLA4 TNFRSF25
2 diabetes mellitus, insulin-dependent, 17 11.8
3 perrault syndrome 1 11.1
4 adrenal cortical hypofunction 10.1 AIRE TNFRSF25
5 type 1 diabetes mellitus 11 10.0 CTLA4 TNFRSF25
6 cholangitis, primary sclerosing 10.0 AIRE TNFRSF25
7 autoimmune disease of gastrointestinal tract 10.0 CTLA4 TNFRSF25
8 autoimmune addison disease 10.0 AIRE CTLA4
9 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.0 AIRE CTLA4
10 vitiligo-associated multiple autoimmune disease susceptibility 1 9.9 AIRE CTLA4
11 childhood type dermatomyositis 9.9 TNFRSF25 VWF
12 hypoadrenocorticism, familial 9.9 AIRE CTLA4
13 autoimmune hepatitis 9.9 AIRE CTLA4
14 alopecia areata 9.9 AIRE CTLA4
15 myasthenia gravis 9.9 AIRE CTLA4
16 thymoma 9.9 AIRE CTLA4
17 type 1 diabetes mellitus 5 9.8 AIRE CTLA4 TNFRSF25
18 autoimmune disease of endocrine system 9.8 AIRE CTLA4 TNFRSF25
19 immune system disease 9.8 AIRE CTLA4 TNFRSF25
20 hashimoto thyroiditis 9.8 AIRE CTLA4
21 celiac disease 1 9.8 CTLA4 TNFRSF25
22 hypothyroidism 9.7 AIRE CTLA4 VWF

Graphical network of the top 20 diseases related to Type 1 Diabetes Mellitus 17:



Diseases related to Type 1 Diabetes Mellitus 17

Symptoms & Phenotypes for Type 1 Diabetes Mellitus 17

Drugs & Therapeutics for Type 1 Diabetes Mellitus 17

Search Clinical Trials , NIH Clinical Center for Type 1 Diabetes Mellitus 17

Genetic Tests for Type 1 Diabetes Mellitus 17

Anatomical Context for Type 1 Diabetes Mellitus 17

MalaCards organs/tissues related to Type 1 Diabetes Mellitus 17:

41
Thyroid, T Cells

Publications for Type 1 Diabetes Mellitus 17

Variations for Type 1 Diabetes Mellitus 17

Expression for Type 1 Diabetes Mellitus 17

Search GEO for disease gene expression data for Type 1 Diabetes Mellitus 17.

Pathways for Type 1 Diabetes Mellitus 17

Pathways related to Type 1 Diabetes Mellitus 17 according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.07 CASP14 CASP7 TNFRSF25
2 10.72 CTLA4 TNFRSF25

GO Terms for Type 1 Diabetes Mellitus 17

Molecular functions related to Type 1 Diabetes Mellitus 17 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cysteine-type endopeptidase activity GO:0004197 8.96 CASP14 CASP7
2 cysteine-type endopeptidase activity involved in apoptotic process GO:0097153 8.62 CASP14 CASP7

Sources for Type 1 Diabetes Mellitus 17

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....