MCID: TYP040
MIFTS: 18

Type 1 Diabetes Mellitus 18

Categories: Metabolic diseases, Endocrine diseases

Aliases & Classifications for Type 1 Diabetes Mellitus 18

MalaCards integrated aliases for Type 1 Diabetes Mellitus 18:

Name: Type 1 Diabetes Mellitus 18 12 15
Diabetes Mellitus, Insulin-Dependent, 18 73
Insulin-Dependent Diabetes Mellitus 18 12
Iddm18 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0110755
ICD10 33 E10
UMLS 73 C1854125

Summaries for Type 1 Diabetes Mellitus 18

Disease Ontology : 12 A type 1 diabetes mellitus that has material basis in mutation of the locus at chromosome 5q31.1-q33.1.

MalaCards based summary : Type 1 Diabetes Mellitus 18, also known as diabetes mellitus, insulin-dependent, 18, is related to diabetes mellitus, insulin-dependent, 18 and diabetes mellitus, insulin-dependent. An important gene associated with Type 1 Diabetes Mellitus 18 is TNFRSF25 (TNF Receptor Superfamily Member 25), and among its related pathways/superpathways are Immune response IFN gamma signaling pathway and Apoptosis and Autophagy.

Related Diseases for Type 1 Diabetes Mellitus 18

Graphical network of the top 20 diseases related to Type 1 Diabetes Mellitus 18:



Diseases related to Type 1 Diabetes Mellitus 18

Symptoms & Phenotypes for Type 1 Diabetes Mellitus 18

Drugs & Therapeutics for Type 1 Diabetes Mellitus 18

Search Clinical Trials , NIH Clinical Center for Type 1 Diabetes Mellitus 18

Genetic Tests for Type 1 Diabetes Mellitus 18

Anatomical Context for Type 1 Diabetes Mellitus 18

Publications for Type 1 Diabetes Mellitus 18

Variations for Type 1 Diabetes Mellitus 18

Expression for Type 1 Diabetes Mellitus 18

Search GEO for disease gene expression data for Type 1 Diabetes Mellitus 18.

Pathways for Type 1 Diabetes Mellitus 18

Pathways related to Type 1 Diabetes Mellitus 18 according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.97 TNFRSF10A TNFRSF25
2 10.89 TNFRSF10A TNFRSF25

GO Terms for Type 1 Diabetes Mellitus 18

Biological processes related to Type 1 Diabetes Mellitus 18 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.43 TNFRSF10A TNFRSF25
2 regulation of apoptotic process GO:0042981 9.4 TNFRSF10A TNFRSF25
3 cell surface receptor signaling pathway GO:0007166 9.37 TNFRSF10A TNFRSF25
4 regulation of cell proliferation GO:0042127 9.32 TNFRSF10A TNFRSF25
5 response to lipopolysaccharide GO:0032496 9.26 TNFRSF10A TNFRSF25
6 positive regulation of MAPK cascade GO:0043410 9.16 TNFRSF10A TNFRSF25
7 tumor necrosis factor-mediated signaling pathway GO:0033209 8.96 TNFRSF10A TNFRSF25
8 apoptotic signaling pathway GO:0097190 8.62 TNFRSF10A TNFRSF25

Molecular functions related to Type 1 Diabetes Mellitus 18 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor activity GO:0038023 8.96 TNFRSF10A TNFRSF25
2 tumor necrosis factor-activated receptor activity GO:0005031 8.62 TNFRSF10A TNFRSF25

Sources for Type 1 Diabetes Mellitus 18

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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