IDDM4
MCID: TYP030
MIFTS: 21

Type 1 Diabetes Mellitus 4 (IDDM4)

Categories: Blood diseases, Endocrine diseases, Genetic diseases, Metabolic diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Type 1 Diabetes Mellitus 4

MalaCards integrated aliases for Type 1 Diabetes Mellitus 4:

Name: Type 1 Diabetes Mellitus 4 12 15
Diabetes Mellitus, Insulin-Dependent, 4 72
Insulin-Dependent Diabetes Mellitus 4 12
Iddm4 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0110743
ICD10 33 E10
UMLS 72 C1838261

Summaries for Type 1 Diabetes Mellitus 4

Disease Ontology : 12 A type 1 diabetes mellitus that has material basis in mutation of the locus at chromosome 11q13.

MalaCards based summary : Type 1 Diabetes Mellitus 4, also known as diabetes mellitus, insulin-dependent, 4, is related to diabetes mellitus, insulin-dependent, 4 and diabetes mellitus, insulin-dependent. An important gene associated with Type 1 Diabetes Mellitus 4 is FGF3 (Fibroblast Growth Factor 3). The drugs Insulin glargine and Gliclazide have been mentioned in the context of this disorder. Related phenotype is skeleton.

Related Diseases for Type 1 Diabetes Mellitus 4

Graphical network of the top 20 diseases related to Type 1 Diabetes Mellitus 4:



Diseases related to Type 1 Diabetes Mellitus 4

Symptoms & Phenotypes for Type 1 Diabetes Mellitus 4

MGI Mouse Phenotypes related to Type 1 Diabetes Mellitus 4:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 skeleton MP:0005390 8.92 FGF3 KMT5B LRP5 SPTBN2

Drugs & Therapeutics for Type 1 Diabetes Mellitus 4

Drugs for Type 1 Diabetes Mellitus 4 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Insulin glargine Approved Phase 4 160337-95-1
2
Gliclazide Approved Phase 4 21187-98-4 3475
3
Zinc Approved, Investigational Phase 4 7440-66-6 32051
4 insulin Phase 4
5 Insulin, Globin Zinc Phase 4
6 Hypoglycemic Agents Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Phase 4 Study of Comparison of Combination Therapy of Gliclazide MR and Basal Insulin With Pre-mix Insulin Monotherapy for the Patients With Type 2 Diabetes Mellitus Completed NCT00736515 Phase 4 Gliclazide MR and Insulin Glargine Injection;Biosynthetic Human Insulin Injection
2 Islet Cell Transplantation Alone in Patients With Type 1 Diabetes Mellitus: Steroid-Free Immunosuppression Active, not recruiting NCT00306098 Phase 2 islets

Search NIH Clinical Center for Type 1 Diabetes Mellitus 4

Genetic Tests for Type 1 Diabetes Mellitus 4

Anatomical Context for Type 1 Diabetes Mellitus 4

Publications for Type 1 Diabetes Mellitus 4

Articles related to Type 1 Diabetes Mellitus 4:

# Title Authors PMID Year
1
Pegylated interferon alfa-2b plus ribavirin for the treatment of chronic hepatitis C genotype 4 in adolescents. 38
20526008 2010
2
[Cardiovascular autonomic neuropathy and nephropathy in patients with type-1 diabetes mellitus]. 38
15518324 2004
3
Linkage and association mapping of the LRP5 locus on chromosome 11q13 in type 1 diabetes. 38
12700977 2003
4
A 3-Mb sequence-ready contig map encompassing the multiple disease gene cluster on chromosome 11q13.1-q13.3. 38
9405936 1997
5
[A case of NIDDM with non-clostridial gas-producing infection in the lower limb--the effects of hyperbaric oxygen therapy]. 38
8151155 1994
6
Preclinical and manifest diabetes mellitus in young patients with Friedreich's ataxia: no evidence of immune process behind the islet cell destruction. 38
2668085 1989

Variations for Type 1 Diabetes Mellitus 4

Expression for Type 1 Diabetes Mellitus 4

Search GEO for disease gene expression data for Type 1 Diabetes Mellitus 4.

Pathways for Type 1 Diabetes Mellitus 4

GO Terms for Type 1 Diabetes Mellitus 4

Sources for Type 1 Diabetes Mellitus 4

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....