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IDDM5
MCID: TYP031
MIFTS: 18

Type 1 Diabetes Mellitus 5 (IDDM5)

Categories: Endocrine diseases, Genetic diseases, Metabolic diseases, Rare diseases
Genes Tissues Related diseases Publications Pathways
Sources

Aliases & Classifications for Type 1 Diabetes Mellitus 5

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MalaCards integrated aliases for Type 1 Diabetes Mellitus 5:

Name: Type 1 Diabetes Mellitus 5 12 15
Diabetes Mellitus, Insulin-Dependent, 5 71
Insulin-Dependent Diabetes Mellitus 5 12
Iddm5 12

Classifications:

MalaCards categories:
Global: Metabolic diseases Rare diseases Genetic diseases
Anatomical: Endocrine diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:0110744
ICD10 32 E10
UMLS 71 C1838260
Sources

Summaries for Type 1 Diabetes Mellitus 5

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Disease Ontology : 12 A type 1 diabetes mellitus that has material basis in mutation of the SUMO4 gene on chromosome 6q25.1.

MalaCards based summary : Type 1 Diabetes Mellitus 5, also known as diabetes mellitus, insulin-dependent, 5, is related to diabetes mellitus, insulin-dependent, 5 and diabetes mellitus, type i. An important gene associated with Type 1 Diabetes Mellitus 5 is SUMO4 (Small Ubiquitin Like Modifier 4), and among its related pathways/superpathways is NF-kB(NFkB) Pathway. Affiliated tissues include heart.

Sources

Related Diseases for Type 1 Diabetes Mellitus 5

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Diseases in the Diabetes Mellitus family:

Diabetes Mellitus, Type I Diabetes Mellitus, Congenital Autoimmune
Type 1 Diabetes Mellitus 2 Type 1 Diabetes Mellitus 3
Type 1 Diabetes Mellitus 4 Type 1 Diabetes Mellitus 5
Type 1 Diabetes Mellitus 6 Type 1 Diabetes Mellitus 7
Type 1 Diabetes Mellitus 8 Type 1 Diabetes Mellitus 10
Type 1 Diabetes Mellitus 11 Type 1 Diabetes Mellitus 12
Type 1 Diabetes Mellitus 13 Type 1 Diabetes Mellitus 15
Type 1 Diabetes Mellitus 17 Type 1 Diabetes Mellitus 18
Rare Diabetes Mellitus Type 1 Rare Diabetes Mellitus Type 2
Rare Diabetes Mellitus

Diseases related to Type 1 Diabetes Mellitus 5 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
# Related Disease Score Top Affiliating Genes
1 diabetes mellitus, insulin-dependent, 5 32.7 TAB2 SUMO4
2 diabetes mellitus, type i 10.3
3 diabetes mellitus, insulin-dependent, 3 10.3
4 diabetes mellitus, insulin-dependent, 4 10.3
5 diabetes mellitus, insulin-dependent, 8 10.3
6 rheumatoid arthritis 10.1
7 diabetes mellitus, insulin-dependent, 7 10.1
8 diabetes mellitus, insulin-dependent, 17 10.1
9 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.1
10 juvenile arthritis 10.1
11 juvenile rheumatoid arthritis 10.1
12 diabetic polyneuropathy 10.0
13 polyneuropathy 10.0
14 type 1 diabetes mellitus 4 9.5 FGF3 BBX
15 type 1 diabetes mellitus 12 9.5 TNFRSF25 SUMO4 EFHB
16 type 1 diabetes mellitus 2 9.2 TNFRSF25 BBX

Graphical network of the top 20 diseases related to Type 1 Diabetes Mellitus 5:



Diseases related to Type 1 Diabetes Mellitus 5
Sources

Symptoms & Phenotypes for Type 1 Diabetes Mellitus 5

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Sources

Drugs & Therapeutics for Type 1 Diabetes Mellitus 5

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Search Clinical Trials , NIH Clinical Center for Type 1 Diabetes Mellitus 5

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Genetic Tests for Type 1 Diabetes Mellitus 5

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Anatomical Context for Type 1 Diabetes Mellitus 5

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MalaCards organs/tissues related to Type 1 Diabetes Mellitus 5:

40
Heart
Sources

Publications for Type 1 Diabetes Mellitus 5

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Articles related to Type 1 Diabetes Mellitus 5:

# Title Authors PMID Year
1
Insulin pump therapy: impact on the lives of children/young people with diabetes mellitus and their parents. 61
25108411 2014
2
Metabolic control in children with insulin-dependent diabetes mellitus 5 y after diagnosis. Early detection of patients at risk for poor metabolic control. 61
9736234 1998
3
Results of heart transplantation by extending recipient selection criteria. 61
7995827 1994
4
Visceral afferent neuropathy in diabetic gastroparesis. 61
1797493 1991
Sources

Variations for Type 1 Diabetes Mellitus 5

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Expression for Type 1 Diabetes Mellitus 5

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Search GEO for disease gene expression data for Type 1 Diabetes Mellitus 5.
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Pathways for Type 1 Diabetes Mellitus 5

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Pathways related to Type 1 Diabetes Mellitus 5 according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
NF-kB(NFkB) Pathway 66
10.63 TAB2 SUMO4
Sources

GO Terms for Type 1 Diabetes Mellitus 5

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Sources

Sources for Type 1 Diabetes Mellitus 5

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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