T1D6
MCID: TYP032
MIFTS: 21

Type 1 Diabetes Mellitus 6 (T1D6)

Categories: Endocrine diseases, Genetic diseases, Immune diseases, Metabolic diseases, Rare diseases

Aliases & Classifications for Type 1 Diabetes Mellitus 6

MalaCards integrated aliases for Type 1 Diabetes Mellitus 6:

Name: Type 1 Diabetes Mellitus 6 57 12 15
Diabetes Mellitus, Insulin-Dependent, 6 57 13 70
Insulin-Dependent Diabetes Mellitus 6 57 12
Iddm6 57 12
Diabetes Mellitus, Insulin-Dependent, 6; Iddm6 57
T1d6 57

Characteristics:

OMIM®:

57 (Updated 20-May-2021)
Inheritance:
autosomal locus and allelic heterogeneity


Classifications:



External Ids:

Disease Ontology 12 DOID:0110745
OMIM® 57 601941
ICD10 32 E10
MedGen 41 C1866041
SNOMED-CT via HPO 68 73211009
UMLS 70 C1866041

Summaries for Type 1 Diabetes Mellitus 6

Disease Ontology : 12 A type 1 diabetes mellitus that has material basis in mutation of the locus at chromosome 18q21.

MalaCards based summary : Type 1 Diabetes Mellitus 6, also known as diabetes mellitus, insulin-dependent, 6, is related to diabetes mellitus and severe combined immunodeficiency. An important gene associated with Type 1 Diabetes Mellitus 6 is IDDM6 (Insulin Dependent Diabetes Mellitus 6), and among its related pathways/superpathways is Colorectal Cancer Metastasis. Related phenotypes are diabetes mellitus and immune system

More information from OMIM: 601941

Related Diseases for Type 1 Diabetes Mellitus 6

Graphical network of the top 20 diseases related to Type 1 Diabetes Mellitus 6:



Diseases related to Type 1 Diabetes Mellitus 6

Symptoms & Phenotypes for Type 1 Diabetes Mellitus 6

Human phenotypes related to Type 1 Diabetes Mellitus 6:

31
# Description HPO Frequency HPO Source Accession
1 diabetes mellitus 31 HP:0000819

Symptoms via clinical synopsis from OMIM®:

57 (Updated 20-May-2021)
Endocrine:
diabetes mellitus, insulin-dependent

Clinical features from OMIM®:

601941 (Updated 20-May-2021)

MGI Mouse Phenotypes related to Type 1 Diabetes Mellitus 6:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.02 DCC FUT2 HLA-DQB1 TCF4 ZNF236

Drugs & Therapeutics for Type 1 Diabetes Mellitus 6

Search Clinical Trials , NIH Clinical Center for Type 1 Diabetes Mellitus 6

Genetic Tests for Type 1 Diabetes Mellitus 6

Anatomical Context for Type 1 Diabetes Mellitus 6

Publications for Type 1 Diabetes Mellitus 6

Articles related to Type 1 Diabetes Mellitus 6:

# Title Authors PMID Year
1
Evidence for a new Graves disease susceptibility locus at chromosome 18q21. 57
10762555 2000
2
Evidence by allelic association-dependent methods for a type 1 diabetes polygene (IDDM6) on chromosome 18q21. 57
9215667 1997
3
Close genetic linkage between diabetes mellitus and kidd blood group. 57
6117683 1981
4
Calculation of HbA1c and glycated albumin from serially measured self-monitored blood glucose in patients with type 1 diabetes mellitus. 61
23933122 2013

Variations for Type 1 Diabetes Mellitus 6

Expression for Type 1 Diabetes Mellitus 6

Search GEO for disease gene expression data for Type 1 Diabetes Mellitus 6.

Pathways for Type 1 Diabetes Mellitus 6

Pathways related to Type 1 Diabetes Mellitus 6 according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.84 TCF4 DCC

GO Terms for Type 1 Diabetes Mellitus 6

Sources for Type 1 Diabetes Mellitus 6

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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