IDDM6
MCID: TYP032
MIFTS: 20

Type 1 Diabetes Mellitus 6 (IDDM6)

Categories: Blood diseases, Endocrine diseases, Genetic diseases, Metabolic diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Type 1 Diabetes Mellitus 6

MalaCards integrated aliases for Type 1 Diabetes Mellitus 6:

Name: Type 1 Diabetes Mellitus 6 12 15
Diabetes Mellitus, Insulin-Dependent, 6 71
Insulin-Dependent Diabetes Mellitus 6 12
Iddm6 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0110745
ICD10 32 E10
UMLS 71 C1866041

Summaries for Type 1 Diabetes Mellitus 6

Disease Ontology : 12 A type 1 diabetes mellitus that has material basis in mutation of the locus at chromosome 18q21.

MalaCards based summary : Type 1 Diabetes Mellitus 6, also known as diabetes mellitus, insulin-dependent, 6, is related to diabetes mellitus, insulin-dependent, 6 and diabetes mellitus, insulin-dependent. An important gene associated with Type 1 Diabetes Mellitus 6 is ZNF236 (Zinc Finger Protein 236), and among its related pathways/superpathways is Colorectal Cancer Metastasis. The drugs Zinc and Insulin glargine have been mentioned in the context of this disorder. Affiliated tissues include kidney.

Related Diseases for Type 1 Diabetes Mellitus 6

Graphical network of the top 20 diseases related to Type 1 Diabetes Mellitus 6:



Diseases related to Type 1 Diabetes Mellitus 6

Symptoms & Phenotypes for Type 1 Diabetes Mellitus 6

Drugs & Therapeutics for Type 1 Diabetes Mellitus 6

Drugs for Type 1 Diabetes Mellitus 6 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Zinc Approved, Investigational Phase 3 7440-66-6 32051
2
Insulin glargine Approved Phase 3 160337-95-1
3 Hypoglycemic Agents Phase 3
4 Insulin, Globin Zinc Phase 3
5 insulin Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 6-Month, Multicenter, Randomized, Open-label, 2-Arm, Parallel-group Study Comparing the Efficacy and Safety of a New Formulation of Insulin Glargine and Lantus® Injected Once Daily in Children and Adolescents Age 6 - 17 Years With Type 1 Diabetes Mellitus With a 6-month Safety Extension Period Completed NCT02735044 Phase 3 Insulin glargine,300 U/mL;Insulin glargine (100 units /mL);Background therapy

Search NIH Clinical Center for Type 1 Diabetes Mellitus 6

Genetic Tests for Type 1 Diabetes Mellitus 6

Anatomical Context for Type 1 Diabetes Mellitus 6

MalaCards organs/tissues related to Type 1 Diabetes Mellitus 6:

40
Kidney

Publications for Type 1 Diabetes Mellitus 6

Articles related to Type 1 Diabetes Mellitus 6:

# Title Authors PMID Year
1
Kidney biopsy findings in children with sickle cell disease: a Midwest Pediatric Nephrology Consortium study. 61
30945006 2019
2
Calculation of HbA1c and glycated albumin from serially measured self-monitored blood glucose in patients with type 1 diabetes mellitus. 61
23933122 2013
3
[Specific factors of diabetes in the rehabilitation of coronary patients]. 61
11004972 2000
4
Organ-specific autoantibodies in coeliac disease: do they represent an epiphenomenon or the expression of associated autoimmune disorders? 61
9265573 1997
5
Pharmacokinetics of aminoguanidine administration and effects on the diabetes frequency in nonobese diabetic mice. 61
8930185 1996
6
Mutation in the mitochondrial tRNA(leu) at position 3243 and spontaneous abortions in Japanese women attending a clinic for diabetic pregnancies. 61
7556983 1995
7
Use of Doppler flow velocity waveform analysis in detection of initial diabetic microangiopathy. 61
2221466 1990
8
Renal effects of nicardipine, a calcium antagonist, in hypertensive type 2 (non-insulin-dependent) diabetic patients with and without nephropathy. 61
2379527 1990
9
[Studies on urinary C-peptide excretion in normal children and children with insulin-dependent diabetes mellitus]. 61
2659621 1989
10
[Serum levels of receptor assayable insulin-like activity in various diseases]. 61
6365608 1983

Variations for Type 1 Diabetes Mellitus 6

Expression for Type 1 Diabetes Mellitus 6

Search GEO for disease gene expression data for Type 1 Diabetes Mellitus 6.

Pathways for Type 1 Diabetes Mellitus 6

Pathways related to Type 1 Diabetes Mellitus 6 according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.84 TCF4 DCC

GO Terms for Type 1 Diabetes Mellitus 6

Sources for Type 1 Diabetes Mellitus 6

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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