MCID: TYP010
MIFTS: 27

Type C Thymoma

Categories: Cancer diseases, Genetic diseases, Immune diseases, Rare diseases

Aliases & Classifications for Type C Thymoma

MalaCards integrated aliases for Type C Thymoma:

Name: Type C Thymoma 12 15
Thymoma, Type C 12 70

Classifications:



External Ids:

Disease Ontology 12 DOID:4554
NCIt 50 C7612
SNOMED-CT 67 15949004
UMLS 70 C1322286

Summaries for Type C Thymoma

MalaCards based summary : Type C Thymoma, also known as thymoma, type c, is related to thymic carcinoma and thymus cancer. An important gene associated with Type C Thymoma is SSTR2 (Somatostatin Receptor 2). Affiliated tissues include thymus, pituitary and thyroid.

Wikipedia : 73 Thymic carcinoma is a rare type of thymus gland cancer. It usually spreads, has a high risk of... more...

Related Diseases for Type C Thymoma

Diseases in the Thymoma family:

Thymoma, Familial Invasive Malignant Thymoma
Type C Thymoma Malignant Type Ab Thymoma
Malignant Type a Thymoma Thymoma Type a
Thymoma Type B Thymoma Type Ab

Diseases related to Type C Thymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 92)
# Related Disease Score Top Affiliating Genes
1 thymic carcinoma 31.9 KIT CD5
2 thymus cancer 31.8 KIT CD5
3 gastrointestinal neuroendocrine tumor 10.2 SSTR2 SST
4 carcinoid tumors, intestinal 10.2 SSTR2 SST
5 hormone producing pituitary cancer 10.2 SSTR2 SST
6 pulmonary neuroendocrine tumor 10.2 SSTR2 SST
7 hyperpituitarism 10.2 SSTR2 SST
8 meningothelial meningioma 10.2 SSTR2 SERPINA3
9 pituitary carcinoma 10.2 SSTR2 SST
10 somatostatinoma 10.2 SSTR2 SST
11 skull base cancer 10.2 SST SERPINA3
12 thyroid gland medullary carcinoma 10.2 SSTR2 SST
13 skull base meningioma 10.2 SST SERPINA3
14 pancreatic cystadenoma 10.2 SSTR2 SST
15 non-langerhans-cell histiocytosis 10.2 SST SERPINA3
16 functioning pituitary adenoma 10.2 SSTR2 SST
17 pancreatoblastoma 10.2 SST SERPINA3
18 acth-secreting pituitary adenoma 10.2 SSTR2 SST
19 growth hormone secreting pituitary adenoma 10.2 SSTR2 SST
20 gastrinoma 10.2 SSTR2 SST
21 appendix lymphoma 10.2 SST CD5
22 gastric hemangioma 10.2 SST KIT
23 cryptosporidiosis 10.1 SST CEMP1
24 rare tumor 10.1 SST KIT
25 tooth resorption 10.1 SERPINA3 CEMP1
26 small intestine benign neoplasm 10.1 SST KIT
27 active peptic ulcer disease 10.1 SST KIT
28 meckel diverticulum 10.1 SST KIT
29 vein disease 10.1 SST SERPINA3
30 cutaneous solitary mastocytoma 10.1 SERPINA3 KIT
31 breast malignant phyllodes tumor 10.1 SERPINA3 KIT
32 gastrointestinal lymphoma 10.1 SERPINA3 CD5
33 embryonal sarcoma 10.1 SERPINA3 KIT
34 heart cancer 10.1 SERPINA3 KIT
35 tenosynovial giant cell tumor 10.1 SERPINA3 KIT
36 malignant spindle cell melanoma 10.1 SERPINA3 KIT
37 bladder sarcoma 10.1 SERPINA3 KIT
38 perivascular tumor 10.1 SERPINA3 KIT
39 fibrosarcoma of bone 10.1 SERPINA3 KIT
40 pleomorphic liposarcoma 10.1 SERPINA3 KIT
41 adenosarcoma 10.1 SERPINA3 KIT
42 pseudosarcomatous fibromatosis 10.1 SERPINA3 KIT
43 mixed cell type cancer 10.1 SERPINA3 KIT
44 amelanotic melanoma 10.1 SERPINA3 KIT
45 islet cell tumor 10.1 SST SERPINA3
46 plasma protein metabolism disease 10.1 SERPINA3 CD5
47 autoimmune disease of blood 10.1 SERPINA3 CD5
48 hemangiopericytoma, malignant 10.1 SERPINA3 KIT
49 mesenchymal cell neoplasm 10.1 SERPINA3 KIT
50 thyroid carcinoma, familial medullary 10.1 SSTR2 SST

Graphical network of the top 20 diseases related to Type C Thymoma:



Diseases related to Type C Thymoma

Symptoms & Phenotypes for Type C Thymoma

Drugs & Therapeutics for Type C Thymoma

Search Clinical Trials , NIH Clinical Center for Type C Thymoma

Genetic Tests for Type C Thymoma

Anatomical Context for Type C Thymoma

MalaCards organs/tissues related to Type C Thymoma:

40
Thymus, Pituitary, Thyroid, Bone, Heart, Smooth Muscle, Skeletal Muscle

Publications for Type C Thymoma

Articles related to Type C Thymoma:

(show all 20)
# Title Authors PMID Year
1
Surgery Resection of a Massive Thymic Carcinoma during Urgent Coronary Artery Bypass Grafting. 61
29983810 2018
2
Inflammatory myopathy associated with myasthenia gravis with and without thymic pathology: Report of four cases and literature review. 61
28414153 2017
3
Identification of prognostic and subtype-specific potential miRNAs in thymoma. 61
28517980 2017
4
Pathologic Finding of Thymic Carcinoma Accompanied by Myasthenia Gravis. 61
26320843 2015
5
Recurrence after thymoma resection according to the extent of the resection. 61
24646138 2014
6
Stiff man syndrome with invasive thymic carcinoma. 61
23432176 2013
7
Different characteristics of thymomas with and without myasthenia gravis. 61
21879277 2012
8
Management of thymic tumors: a survey of current practice among members of the European Society of Thoracic Surgeons. 61
21266921 2011
9
Thymic basaloid carcinoma: a clinicopathologic study of 12 cases, with a general discussion of basaloid carcinoma and its relationship with adenoid cystic carcinoma. 61
19461509 2009
10
[Histologic subtyping and prognosis of thymoma: a study of 108 cases]. 61
19035114 2008
11
Advanced pediatric inoperable thymus carcinoma (type C thymoma): case report on a novel therapeutic approach. 61
17984697 2007
12
Malignant thymoma associated with mixed connective tissue disease: a case report. 61
16010443 2006
13
Expression of neurotrophin receptors in surgically resected thymic epithelial tumors. 61
16125946 2005
14
WHO histologic classification is a prognostic indicator in thymoma. 61
15063231 2004
15
Hepatoid thymic carcinoma: report of a case. 61
15043316 2004
16
Expression of matrix metalloproteinases 2 and 7 in tumor cells correlates with the World Health Organization classification subtype and clinical stage of thymic epithelial tumors. 61
14691910 2003
17
Clusters of chromosomal imbalances in thymic epithelial tumours are associated with the WHO classification and the staging system according to Masaoka. 61
12712440 2003
18
Proliferative activity and apoptosis in thymic epithelial neoplasms. 61
12481014 2002
19
[Assessment of mode of recurrence after surgical treatment for thymic carcinoma]. 61
12391696 2002
20
Pseudodicentric (16;12)(q11;p11.2) in a type AB (mixed) thymoma. 61
11734317 2001

Variations for Type C Thymoma

Cosmic variations for Type C Thymoma:

9 (show all 36)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM105695698 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.376T>A p.Y126N 17:7675236-7675236 3
2 COSM142891951 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.376T>A p.Y126N 17:7675236-7675236 3
3 COSM87975416 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.376T>A p.Y126N 17:7675236-7675236 3
4 COSM142627127 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.259T>A p.Y87N 17:7675236-7675236 3
5 COSM121944830 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.-21T>A p.? 17:7675236-7675236 3
6 COSM106116533 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.376T>A p.Y126N 17:7675236-7675236 3
7 COSM144072853 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.343T>A p.Y115N 17:7675236-7675236 3
8 COSM144363948 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.259T>A p.Y87N 17:7675236-7675236 3
9 COSM122332176 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.-21T>A p.? 17:7675236-7675236 3
10 COSM93250189 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.376T>A p.Y126N 17:7675236-7675236 3
11 COSM145076506 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.259T>A p.Y87N 17:7675236-7675236 3
12 COSM122804157 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.-21T>A p.? 17:7675236-7675236 3
13 COSM144718880 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.259T>A p.Y87N 17:7675236-7675236 3
14 COSM144140974 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.-102T>A p.? 17:7675236-7675236 3
15 COSM112319052 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.376T>A p.Y126N 17:7675236-7675236 3
16 COSM143214478 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.-102T>A p.? 17:7675236-7675236 3
17 COSM143433019 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.259T>A p.Y87N 17:7675236-7675236 3
18 COSM111826108 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.376T>A p.Y126N 17:7675236-7675236 3
19 COSM144005441 TP53 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.-102T>A p.? 17:7675236-7675236 3
20 COSM103083119 SMAD4 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.1081C>T p.R361C 18:51065548-51065548 3
21 COSM139771670 SMAD4 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.793C>T p.R265C 18:51065548-51065548 3
22 COSM91380576 SMAD4 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.1081C>T p.R361C 18:51065548-51065548 3
23 COSM88596522 PREX2 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.107G>T p.R36L 8:67952501-67952501 3
24 COSM88408638 NOTCH2 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.3359G>A p.C1120Y 1:119937445-119937445 3
25 COSM87667907 KMT2D thymus,NS,thymic carcinoma,undifferentiated carcinoma c.12634C>T p.R4212W 12:49032071-49032071 3
26 COSM88314740 KIT thymus,NS,thymic carcinoma,undifferentiated carcinoma c.1657T>A p.Y553N 4:54727425-54727425 3
27 COSM132270273 KDM6A thymus,NS,thymic carcinoma,undifferentiated carcinoma c.2768C>T p.A923V 23:45078488-45078488 3
28 COSM101719617 KDM6A thymus,NS,thymic carcinoma,undifferentiated carcinoma c.2870C>T p.A957V 23:45078488-45078488 3
29 COSM145420036 KDM6A thymus,NS,thymic carcinoma,undifferentiated carcinoma c.*1915C>T p.? 23:45078488-45078488 3
30 COSM143359668 KDM6A thymus,NS,thymic carcinoma,undifferentiated carcinoma c.3005C>T p.A1002V 23:45078488-45078488 3
31 COSM102181889 KDM6A thymus,NS,thymic carcinoma,undifferentiated carcinoma c.2921C>T p.A974V 23:45078488-45078488 3
32 COSM132025397 KDM6A thymus,NS,thymic carcinoma,undifferentiated carcinoma c.2714C>T p.A905V 23:45078488-45078488 3
33 COSM85170206 IL7R thymus,NS,thymic carcinoma,undifferentiated carcinoma c.537+1G>T p.? 5:35871214-35871214 3
34 COSM121730466 IL7R thymus,NS,thymic carcinoma,undifferentiated carcinoma c.537+1G>T p.? 5:35871214-35871214 3
35 COSM143857324 FAT1 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.12712A>G p.K4238E 4:186596834-186596834 3
36 COSM110448949 FAT1 thymus,NS,thymic carcinoma,undifferentiated carcinoma c.12706A>G p.K4236E 4:186596834-186596834 3

Expression for Type C Thymoma

Search GEO for disease gene expression data for Type C Thymoma.

Pathways for Type C Thymoma

GO Terms for Type C Thymoma

Biological processes related to Type C Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hemopoiesis GO:0030097 8.62 KIT FOXN1

Sources for Type C Thymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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