MCID: ULC006
MIFTS: 26

Ulceroglandular Tularemia

Categories: Infectious diseases

Aliases & Classifications for Ulceroglandular Tularemia

MalaCards integrated aliases for Ulceroglandular Tularemia:

Name: Ulceroglandular Tularemia 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:11990
ICD10 33 A21.0
ICD9CM 35 021.0
SNOMED-CT 68 37722001
UMLS 73 C0152941

Summaries for Ulceroglandular Tularemia

Disease Ontology : 12 A tularemia that results in painful regional lymphadenopathy and an ulcerated skin lesion.

MalaCards based summary : Ulceroglandular Tularemia is related to tularemia and guillain-barre syndrome. An important gene associated with Ulceroglandular Tularemia is STAB2 (Stabilin 2), and among its related pathways/superpathways are Necroptosis and Immune response IFN gamma signaling pathway. Affiliated tissues include skin, and related phenotypes are cardiovascular system and neoplasm

Related Diseases for Ulceroglandular Tularemia

Diseases related to Ulceroglandular Tularemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 15)
# Related Disease Score Top Affiliating Genes
1 tularemia 31.4 CASP1 PDE6B STAB2
2 guillain-barre syndrome 10.4
3 erysipelas 10.2
4 pneumonia 10.2
5 glandular tularemia 10.1 CRP STAB2
6 paratyphoid fever 10.1 CASP1 CRP
7 tuberculous peritonitis 10.1 CRP PDE6B
8 typhoid fever 10.1 CASP1 CRP
9 muckle-wells syndrome 10.0 CASP1 CRP
10 salmonellosis 10.0 CASP1 STAT1
11 severe acute respiratory syndrome 10.0 CRP STAT1
12 primary bacterial infectious disease 10.0 CRP PDE6B
13 familial mediterranean fever 9.9 CASP1 CRP
14 chlamydia 9.9 CASP1 CRP
15 chronic active epstein-barr virus infection 9.9 GBP1 TNFAIP6

Graphical network of the top 20 diseases related to Ulceroglandular Tularemia:



Diseases related to Ulceroglandular Tularemia

Symptoms & Phenotypes for Ulceroglandular Tularemia

MGI Mouse Phenotypes related to Ulceroglandular Tularemia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.43 CASP1 CRP PDE6B STAB2 STAT1 TNFSF10
2 neoplasm MP:0002006 9.02 CASP1 PSME2 STAB2 STAT1 TNFSF10

Drugs & Therapeutics for Ulceroglandular Tularemia

Search Clinical Trials , NIH Clinical Center for Ulceroglandular Tularemia

Genetic Tests for Ulceroglandular Tularemia

Anatomical Context for Ulceroglandular Tularemia

MalaCards organs/tissues related to Ulceroglandular Tularemia:

41
Skin

Publications for Ulceroglandular Tularemia

Articles related to Ulceroglandular Tularemia:

(show all 24)
# Title Authors Year
1
A case of ulceroglandular tularemia presenting with lymphadenopathy and an ulcer on a linear morphoea lesion surrounded by erysipelas. ( 30519119 )
2018
2
Clinical Characteristics of Ulceroglandular Tularemia in Two Bulgarian Regions, 2014-2015: a Report of Five Cases. ( 29341950 )
2017
3
Imaging Findings of Ulceroglandular Tularemia. ( 28580063 )
2017
4
Ulceroglandular Tularemia Following Contact with a Boar. ( 26658527 )
2016
5
Cluster of ulceroglandular tularemia cases in Slovenia. ( 27496749 )
2016
6
About three cases of ulceroglandular tularemia, is this the re-emergence of F. tularensis in Belgium? ( 25847026 )
2015
7
Ulceroglandular tularemia complicated by pneumonia--a case report. ( 25391005 )
2014
8
Guillain-BarrAc syndrome and ulceroglandular tularemia. ( 23712689 )
2013
9
Guillain-Barré syndrome and ulceroglandular tularemia. ( 23896779 )
2013
10
Ulceroglandular tularemia. ( 20678093 )
2011
11
Ulceroglandular tularemia. ( 21501382 )
2011
12
Ulceroglandular tularemia in a toddler in Germany after a mosquito bite. ( 19132387 )
2009
13
Ulceroglandular tularemia in a nonendemic area. ( 17396737 )
2007
14
Localized cutaneous infection with Francisella tularensis resembling ulceroglandular tularemia in a cat. ( 14974853 )
2004
15
Rapid laboratory diagnosis of ulceroglandular tularemia with polymerase chain reaction. ( 11440227 )
2001
16
Comparative analysis of PCR versus culture for diagnosis of ulceroglandular tularemia. ( 10618057 )
2000
17
Index of suspicion. Case 2. Diagnosis: ulceroglandular tularemia. ( 8992473 )
1996
18
Use of RNA hybridization in the diagnosis of a case of ulceroglandular tularemia. ( 1702055 )
1990
19
Ulceroglandular tularemia: a typical case of relapse. ( 2606733 )
1989
20
Tick-borne ulceroglandular tularemia. ( 6579402 )
1983
21
Hepatic abscess complicating ulceroglandular tularemia. ( 6652596 )
1983
22
GUILLAIN-BARRE SYNDROME ASSOCIATED WITH ULCEROGLANDULAR TULAREMIA. ( 14215606 )
1964
23
Ulceroglandular tularemia treated by chloromycetin. ( 24541925 )
1952
24
Ulceroglandular tularemia treated with streptomycin; a report of two cases. ( 18908319 )
1948

Variations for Ulceroglandular Tularemia

Expression for Ulceroglandular Tularemia

Search GEO for disease gene expression data for Ulceroglandular Tularemia.

Pathways for Ulceroglandular Tularemia

Pathways related to Ulceroglandular Tularemia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.57 CASP1 STAT1 TNFSF10
2
Show member pathways
11.51 CASP1 STAT1 TNFSF10
3 10.82 GBP1 STAT1
4 10.77 CRP PDE6B STAT1
5 10.49 CRP PDE6B STAT1

GO Terms for Ulceroglandular Tularemia

Biological processes related to Ulceroglandular Tularemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 9.77 CASP1 PDE6B STAT1 TNFAIP6 TNFSF10
2 interferon-gamma-mediated signaling pathway GO:0060333 9.32 GBP1 STAT1
3 cellular response to cytokine stimulus GO:0071345 9.26 CASP1 STAT1
4 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280 9.16 CASP1 TNFSF10
5 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 9.13 CASP1 SECTM1 TNFSF10
6 cellular response to interferon-gamma GO:0071346 8.8 CASP1 GBP1 STAT1

Molecular functions related to Ulceroglandular Tularemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tumor necrosis factor receptor binding GO:0005164 9.26 STAT1 TNFSF10
2 hyaluronic acid binding GO:0005540 9.16 STAB2 TNFAIP6
3 identical protein binding GO:0042802 9.1 CASP1 CRP GBP1 PSME2 STAT1 TNFSF10
4 low-density lipoprotein particle binding GO:0030169 8.96 CRP STAB2

Sources for Ulceroglandular Tularemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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