MCID: ULN002
MIFTS: 31

Ulnar Nerve Lesion

Categories: Neuronal diseases

Aliases & Classifications for Ulnar Nerve Lesion

MalaCards integrated aliases for Ulnar Nerve Lesion:

Name: Ulnar Nerve Lesion 12 15
Lesion of Ulnar Nerve 12 70 32

Classifications:



External Ids:

Disease Ontology 12 DOID:12168
ICD9CM 34 354.2
SNOMED-CT 67 55802003
ICD10 32 G56.2
UMLS 70 C1288279

Summaries for Ulnar Nerve Lesion

MalaCards based summary : Ulnar Nerve Lesion, also known as lesion of ulnar nerve, is related to radial neuropathy and borderline leprosy. An important gene associated with Ulnar Nerve Lesion is CCDC122 (Coiled-Coil Domain Containing 122), and among its related pathways/superpathways are NF-kappaB Signaling and Tuberculosis. Affiliated tissues include bone and heart, and related phenotypes are hematopoietic system and immune system

Related Diseases for Ulnar Nerve Lesion

Diseases related to Ulnar Nerve Lesion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Related Disease Score Top Affiliating Genes
1 radial neuropathy 10.4 TOR1B CCDC122
2 borderline leprosy 10.3 TOR1B CCDC122
3 post-transplant lymphoproliferative disease 10.3 SLC11A1 LTA
4 parkinson disease 10 10.2 PRKN LRRK2
5 gastrointestinal tularemia 10.2 TLR1 SLC11A1
6 color agnosia 10.2 PRKN LRRK2
7 postencephalitic parkinson disease 10.2 PRKN LRRK2
8 parkinson disease 21 10.2 PRKN LRRK2
9 ophthalmomyiasis 10.1 PRKN LRRK2
10 ulnar neuropathy 10.1
11 muscular atrophy 10.1
12 inflammatory bowel disease 15 10.1 TNFSF15 NOD2
13 reflex sympathetic dystrophy 10.1 TOR1B TAC1
14 immunoglobulin a deficiency 1 10.1 TNFRSF25 LTA
15 ocular toxoplasmosis 10.1 TLR1 NOD2
16 punctate epithelial keratoconjunctivitis 10.1 TNFRSF25 TAC1
17 somatization disorder 10.0 TAC1 COMT
18 campylobacteriosis 10.0 VDR SLC11A1
19 inflammatory bowel disease 1 10.0 TNFSF15 RIPK2 NOD2
20 carpal tunnel syndrome 10.0
21 syringomyelia, noncommunicating isolated 10.0
22 chondrocalcinosis 10.0
23 syringomyelia 10.0
24 arthropathy 10.0
25 cutaneous anthrax 10.0
26 anthrax disease 10.0
27 neuropathy 10.0
28 paresthesia 10.0
29 essential tremor 10.0 PRKN LRRK2 COMT
30 inflammatory bowel disease 19 10.0 TNFSF15 NOD2
31 indeterminate leprosy 10.0 TOR1B TLR1 SLC11A1 RIPK2 CCDC122
32 q fever 10.0 TLR1 SLC11A1 NOD2
33 gaucher's disease 10.0 PRKN MRC1 LRRK2
34 acute apical periodontitis 9.9 TAC1 BMP2
35 primary bacterial infectious disease 9.9 TLR1 SLC11A1 NOD2
36 sleep disorder 9.9 TAC1 LRRK2 COMT
37 chromosome 8q21.11 deletion syndrome 9.9 RIPK2 IL7
38 cholangitis, primary sclerosing 9.9 TNFRSF25 NOD2 DLAT
39 erythema nodosum 9.9 VDR NOD2 LTA
40 salmonellosis 9.9 VDR SLC11A1 NOD2
41 lymphadenitis 9.9 VDR SLC11A1 NOD2
42 dementia, lewy body 9.8 PRKN LRRK2 COMT
43 anorectal stricture 9.8 TNFSF15 NOD2
44 degenerative disc disease 9.8 VDR COMT BMP2
45 crohn's disease 9.8 TNFSF15 RIPK2 NOD2 LRRK2
46 autoimmune disease of gastrointestinal tract 9.8 TNFSF15 TNFRSF25 NOD2 DLAT
47 movement disease 9.6 TOR1B TAC1 PRKN LRRK2 COMT
48 radiculopathy 9.6 TAC1 IL7 BMP2
49 disease by infectious agent 9.5 SLC11A1 NOD2 LTA IL7
50 bone disease 9.4 VDR LTA IL7 BMP2

Comorbidity relations with Ulnar Nerve Lesion via Phenotypic Disease Network (PDN):


Hypertension, Essential Mononeuropathy of the Median Nerve, Mild

Graphical network of the top 20 diseases related to Ulnar Nerve Lesion:



Diseases related to Ulnar Nerve Lesion

Symptoms & Phenotypes for Ulnar Nerve Lesion

MGI Mouse Phenotypes related to Ulnar Nerve Lesion:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.8 BMP2 CCDC122 COMT IL7 LRRK2 LTA
2 immune system MP:0005387 9.44 BMP2 COMT IL7 LRRK2 LTA MRC1

Drugs & Therapeutics for Ulnar Nerve Lesion

Search Clinical Trials , NIH Clinical Center for Ulnar Nerve Lesion

Genetic Tests for Ulnar Nerve Lesion

Anatomical Context for Ulnar Nerve Lesion

MalaCards organs/tissues related to Ulnar Nerve Lesion:

40
Bone, Heart

Publications for Ulnar Nerve Lesion

Articles related to Ulnar Nerve Lesion:

(show top 50) (show all 73)
# Title Authors PMID Year
1
Effects of serious games in strength and functionality of patients with ulnar nerve lesion: two single-case reports. 61
32769585 2020
2
Prior to Repair Functional Deficits in Above- and Below-Elbow Ulnar Nerve Injury. 61
31917047 2020
3
Anaplastic lymphoma receptor tyrosine kinase-negative inflammatory myofibroblastic tumor of triceps brachii: Case report. 61
32962596 2020
4
'Bony' cubital tunnel syndrome caused by heterotopic ossification. 61
29020815 2019
5
Risk of ulnar nerve injury during cross-pinning in supine and prone position for supracondylar humeral fractures in children: a recent literature review. 61
31037406 2019
6
Supercharge End-to-Side Nerve Transfer: Systematic Review. 61
30924361 2019
7
Transferring the Motor Branch of the Opponens Pollicis to the Terminal Division of the Deep Branch of the Ulnar Nerve for Pinch Reconstruction. 61
30366737 2019
8
Predictive value of metacarpophalangeal stabilization tests for simulated ulnar nerve lesion measured by a sensor glove. 61
29042158 2019
9
Quantification of hand function by power grip and pinch strength force measurements in ulnar nerve lesion simulated by ulnar nerve block. 61
28655474 2018
10
Comparison of a single approach versus double approaches for the treatment of terrible traid of elbow-A retrospective study. 61
29367033 2018
11
Fat Grafting for Esthetic Correction of the Muscle Atrophy Secondary to Ulnar Nerve Lesion. 61
28614273 2017
12
Treatment of displaced supracondylar humeral fractures in children by humero-ulnar external fixation. 61
27506570 2016
13
Ultrasound Diagnosis of Double Crush Syndrome of the Ulnar Nerve by the Anconeus Epitrochlearis and a Ganglion. 61
26885291 2016
14
Distal humerus prosthetic hemiarthroplasty: midterm results. 61
26311568 2015
15
Ulnar nerve lesion at the wrist and sport: A report of 8 cases compared with 45 non-sport cases. 61
25794696 2015
16
The median nerve consistently drives flexion of the distal phalanx of the ring and little fingers: Interest in finger flexion reconstruction by nerve transfers. 61
25256625 2015
17
[LUCL reconstruction using a triceps tendon graft to treat posterolateral rotatory instability of the elbow]. 61
24253071 2014
18
Electrophysiological pattern of 53 cases of ulnar nerve lesion at the wrist. 61
23540258 2013
19
Ulnar nerve lesion at the wrist related to pisotriquetral joint arthropathy. 61
23463648 2013
20
Functional outcome of flexor tendon repair of the hand at Zone 5 and post operative early mobilization of the fingers. 61
24353505 2013
21
Supracondylar humerus fractures in children treated with closed reduction and percutaneous pinning. 61
22821604 2012
22
Dorsal percutaneous cannulated mini-screw fixation for fractures of the hamate hook. 61
22745102 2012
23
The pattern of muscle involvement in ulnar neuropathy at the elbow. 61
22406777 2012
24
MR neurography in ulnar neuropathy as surrogate parameter for the presence of disseminated neuropathy. 61
23166762 2012
25
[Neurotization of the deep branch of ulnar nerve with anterior interosseous nerve: anatomic study]. 61
22094175 2011
26
An unusual location of ulnar nerve pathology: a perineurioma of the ulnar nerve in the upper arm. 61
21922473 2011
27
[Results of primary repair of injuries to the median and ulnar nerves at the wrist]. 61
19246233 2009
28
Indirect decompression of the carpal tunnel during basal joint arthroplasty of the thumb. 61
18762097 2008
29
Reconstruction of Mason type-III and type-IV radial head fractures with a new fixation device: 23 patients followed 1-4 years. 61
17453407 2007
30
Multifocal acquired demyelinating sensory and motor neuropathy presenting as a peripheral nerve tumor. 61
16609974 2006
31
Frequency of neurogenic thoracic outlet syndrome in patients with definite carpal tunnel syndrome: an electrophysiological evaluation in 100 women. 61
15661102 2005
32
[Anatomical changes and dynamic analysis after anterior submuscular transposition in treating cubital tunnel syndrome]. 61
15323433 2004
33
The ultrasonographic and electrodiagnostic findings of ulnar neuropathy at the elbow. 61
15179657 2004
34
Surgical outcomes of ulnar nerve lesions in children. A retrospective clinical study. 61
15367799 2004
35
[Wartenberg's Sign of Ulnar Nerve Lesion. A Contribution to Pathophysiology and to the Differential Diagnosis]. 61
12968223 2003
36
Use of vein grafts in emergency in peripheral nerve defect. 61
12029234 2002
37
Is the ulnar nerve damaged in 'handball goalie's elbow'? 61
11476431 2001
38
[The actualization of heteronomous monosynaptic connections of IA afferents in the muscle motor centers of the human hand]. 61
10741179 2000
39
Ulnar nerve lesion due to cutaneous anthrax. 61
10597826 1999
40
Ulnar conduction block at the wrist. 61
10527100 1999
41
The effect of a peripheral nerve lesion on calbindin D28k immunoreactivity in the cervical ventral horn of developing and adult rats. 61
10192782 1999
42
Palmaris brevis sign in ulnar neuropathy 1998. 61
9572255 1998
43
Ulnar nerve lesion in the palm: report of an unusual case. 61
9111467 1997
44
Splinting and local steroid injection for the treatment of ulnar neuropathy at the elbow: clinical and electrophysiological evaluation. 61
8831474 1996
45
Lumbrical-interosseous comparison in a distal ulnar nerve lesion. 61
8618571 1996
46
Does an ulnar nerve lesion influence the motion of the index finger? 61
8732411 1996
47
Nerve injury following steroid injection for carpal tunnel syndrome. A report of two cases. 61
8732402 1996
48
Operative treatment of distal humeral fractures in the elderly. 61
8083271 1994
49
[Neurological assessment of health status in dentists]. 61
8084261 1994
50
The importance of neurophysiological evaluation of plexus brachialis injury caused by open heart surgery. 61
8449170 1993

Variations for Ulnar Nerve Lesion

Expression for Ulnar Nerve Lesion

Search GEO for disease gene expression data for Ulnar Nerve Lesion.

Pathways for Ulnar Nerve Lesion

Pathways related to Ulnar Nerve Lesion according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.97 TNFSF15 TNFRSF25 TLR1 RIPK2
2 11.28 VDR TLR1 RIPK2 NOD2 MRC1
3
Show member pathways
11.05 TNFSF15 TNFRSF25 LTA

GO Terms for Ulnar Nerve Lesion

Cellular components related to Ulnar Nerve Lesion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 presynaptic cytosol GO:0099523 8.96 LRRK2 CALB1
2 terminal bouton GO:0043195 8.8 SLC18A3 LRRK2 CALB1

Biological processes related to Ulnar Nerve Lesion according to GeneCards Suite gene sharing:

(show all 33)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 10 VDR SLC11A1 PRKN IL7 BMP2
2 immune response GO:0006955 9.98 TNFSF15 TLR1 SLC11A1 LTA IL7
3 regulation of apoptotic process GO:0042981 9.92 TNFRSF25 RIPK2 PRKN NOD2
4 cell-cell signaling GO:0007267 9.87 TAC1 LTA IL7 BMP2
5 defense response to Gram-positive bacterium GO:0050830 9.81 RIPK2 NOD2 LTA
6 inflammatory response GO:0006954 9.8 TLR1 TAC1 SLC11A1 RIPK2 BMP2
7 positive regulation of interleukin-6 production GO:0032755 9.79 TLR1 RIPK2 NOD2
8 positive regulation of tumor necrosis factor production GO:0032760 9.79 TLR1 RIPK2 NOD2
9 positive regulation of protein ubiquitination GO:0031398 9.73 RIPK2 NOD2 LRRK2
10 cellular response to organic cyclic compound GO:0071407 9.7 NOD2 LRRK2 BMP2
11 positive regulation of interferon-gamma production GO:0032729 9.67 SLC11A1 RIPK2 LTA
12 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway GO:1902236 9.66 PRKN LRRK2
13 response to pain GO:0048265 9.65 TAC1 COMT
14 dopamine metabolic process GO:0042417 9.65 PRKN COMT
15 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.65 NOD2 LRRK2
16 positive regulation of ossification GO:0045778 9.64 TAC1 BMP2
17 cellular response to dopamine GO:1903351 9.63 PRKN LRRK2
18 macrophage activation GO:0042116 9.63 TLR1 SLC11A1
19 short-term memory GO:0007614 9.6 COMT CALB1
20 positive regulation of T-helper 1 type immune response GO:0002827 9.59 SLC11A1 RIPK2
21 positive regulation of cytokine-mediated signaling pathway GO:0001961 9.58 RIPK2 IL7
22 cellular response to manganese ion GO:0071287 9.55 PRKN LRRK2
23 cellular response to muramyl dipeptide GO:0071225 9.54 RIPK2 NOD2
24 nucleotide-binding oligomerization domain containing 2 signaling pathway GO:0070431 9.51 RIPK2 NOD2
25 positive regulation of xenophagy GO:1904417 9.48 RIPK2 NOD2
26 protein localization to mitochondrion GO:0070585 9.46 PRKN LRRK2
27 activation of MAPK activity GO:0000187 9.46 RIPK2 NOD2 LRRK2 BMP2
28 positive regulation of dendritic cell antigen processing and presentation GO:0002606 9.43 SLC11A1 NOD2
29 cellular response to peptidoglycan GO:0071224 9.37 RIPK2 NOD2
30 positive regulation of humoral immune response mediated by circulating immunoglobulin GO:0002925 9.32 NOD2 LTA
31 regulation of synaptic vesicle transport GO:1902803 9.26 PRKN LRRK2
32 positive regulation of protein binding GO:0032092 9.26 RIPK2 PRKN LRRK2 BMP2
33 response to lipopolysaccharide GO:0032496 9.02 TAC1 SLC11A1 NOD2 LTA COMT

Molecular functions related to Ulnar Nerve Lesion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 CARD domain binding GO:0050700 9.16 RIPK2 NOD2
2 co-receptor binding GO:0039706 8.96 LRRK2 BMP2
3 cytokine activity GO:0005125 8.92 TNFSF15 LTA IL7 BMP2

Sources for Ulnar Nerve Lesion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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