MCID: UND004
MIFTS: 24

Undetermined Colitis

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Undetermined Colitis

MalaCards integrated aliases for Undetermined Colitis:

Name: Undetermined Colitis 58
Indeterminate Colitis 71 32

Classifications:

Orphanet: 58  
Rare gastroenterological diseases


External Ids:

ICD10 32 K52.3
ICD10 via Orphanet 33 K52.3
Orphanet 58 ORPHA103920
UMLS 71 C0341332

Summaries for Undetermined Colitis

MalaCards based summary : Undetermined Colitis, also known as indeterminate colitis, is related to pouchitis and crohn's disease. The drugs Neomycin and Ciprofloxacin have been mentioned in the context of this disorder. Affiliated tissues include colon, bone and liver.

Related Diseases for Undetermined Colitis

Diseases related to Undetermined Colitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 25)
# Related Disease Score Top Affiliating Genes
1 pouchitis 11.8
2 crohn's disease 10.7
3 inflammatory bowel disease 10.6
4 ileitis 10.1
5 megacolon 10.1
6 proctitis 10.1
7 familial adenomatous polyposis 10.0
8 toxic megacolon 10.0
9 graft-versus-host disease 9.9
10 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.9
11 diversion colitis 9.9
12 sensorineural hearing loss 9.9
13 diarrhea 9.9
14 rectum cancer 9.9
15 endometriosis 9.9
16 adenocarcinoma 9.9
17 plague 9.9
18 intestinal disease 9.9
19 herpes zoster 9.9
20 irritable bowel syndrome 9.9
21 cytokine deficiency 9.9
22 tremor 9.9
23 colitis 9.8
24 crohn's colitis 9.8
25 ulcerative colitis 9.8

Graphical network of the top 20 diseases related to Undetermined Colitis:



Diseases related to Undetermined Colitis

Symptoms & Phenotypes for Undetermined Colitis

Drugs & Therapeutics for Undetermined Colitis

Drugs for Undetermined Colitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 24)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Neomycin Approved, Vet_approved Phase 2 1404-04-2 8378
2
Ciprofloxacin Approved, Investigational Phase 2 85721-33-1 2764
3
Fluconazole Approved, Investigational Phase 2 86386-73-4 3365
4
Clotrimazole Approved, Vet_approved Phase 2 23593-75-1 2812
5
Vancomycin Approved Phase 2 1404-90-6 14969 441141
6
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
7 Hormone Antagonists Phase 2
8 Laxatives Phase 2
9 Cytochrome P-450 Enzyme Inhibitors Phase 2
10 Anti-Infective Agents Phase 2
11 Cathartics Phase 2
12 Hormones Phase 2
13 Antifungal Agents Phase 2
14 Anti-Bacterial Agents Phase 2
15 Gastrointestinal Agents Phase 2
16 Polyethylene glycol 3350 Phase 2
17
Infliximab Approved 170277-31-3
18 Antibodies, Monoclonal
19 Antibodies
20 Immunoglobulins
21 Adjuvants, Immunologic
22 Dermatologic Agents
23 Antirheumatic Agents
24 Janus Kinase Inhibitors

Interventional clinical trials:

(show all 26)
# Name Status NCT ID Phase Drugs
1 An Open-Label Pilot Study of Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease Active, not recruiting NCT03476317 Phase 2 Vancomycin;Neomycin;Ciprofloxacin;Polyethylene Glycol 3350;Fluconazole
2 A Study for Evaluation of Clinical Response to Single vs. Maintenance Fecal Microbiota Transplantation in Pediatric Patients With Refractory Crohn's Disease Not yet recruiting NCT03747718 Phase 1
3 Safety of Anti-TNF Antibodies, Including Biosimilars, in Treatment of Inflammatory Bowel Disease: Multicentre Cohort Observational Study (SATIMOS) Unknown status NCT02066272
4 Endomicroscopy for Assessment of Structural and Functional Changes in IBD Patients Treated With Anti-TNFalpha - Insights in the Process in Mucosal Healing Unknown status NCT01417728
5 CALFE Stool Sample Collection Protocol Completed NCT03143517
6 Clinical Study of the BÜHLMANN fCAL™ ELISA as an Aid in the Differentiation of Inflammatory Bowel Disease From Irritable Bowel Syndrome Completed NCT02351635
7 Surgical Decision Making Among People With Inflammatory Bowel Disease Completed NCT00438711
8 Study of Anti-glycan Antibodies Stability in Saint-Etienne IBD Cohort - A Monocentric Study Completed NCT02502552
9 Treatment and Long-term Outcomes of Pediatric Patient With Penetrating Crohn's Disease: the Multicenter Cross-sectional Study Completed NCT04119635
10 Comparison of the Use of Wireless Capsule Endoscopy With Magnetic Resonance Enterography in Children With Inflammatory Bowel Disease Completed NCT02182947
11 Telephone Consultation as a Substitute for Routine Out-patient Face-to-face Consultation for Children With Inflammatory Bowel Disease: Randomised Controlled Trial and Economic Evaluation. Completed NCT02319798
12 Infectious Agents in Pediatric Crohn's Disease Completed NCT00237055
13 Growth Relapse and Outcomes With Therapy 1:Factors Determining Poor Outcomes in Pediatric Crohn"s Disease Completed NCT00711945
14 Colitis Prospective Cohort Study: Determining the Aetiologies of Acute Colitis and Developing a Diagnostic Score to Identify Patients Requiring Specific Investigations Completed NCT02709213
15 Investigation of Vascular Endothelial Dysfunction, Thromboembolism and Structural Arterial Disease in Paediatric and Adolescent Inflammatory Bowel Disease (IBD) Completed NCT02161640
16 A 5-year Longitudinal Observational Study of Patients Undergoing Therapy for Inflammatory Bowel Disease Recruiting NCT03251118
17 Multi-Center African-American Inflammatory Bowel Disease Study (MAAIS) Recruiting NCT01169194
18 Prospective and Multicenter Study About the Epidemiology and the Characteristics "Omics" in Patients Recently Diagnosed of Inflammatory Bowel Disease in Spain Recruiting NCT03689257
19 Fecal Microbial Transplantation in Patients With Medication Refractory Clostridium Difficile and/or Ulcerative Colitis or Indeterminate Colitis Active, not recruiting NCT03268213 Early Phase 1
20 Johns Hopkins Crohn's Disease and Ulcerative Colitis Study Active, not recruiting NCT01169207
21 A Multicenter, Prospective, Long-term, Observational Registry of Pediatric Patients With Inflammatory Bowel Disease Active, not recruiting NCT00606346 No Biologics
22 Gene Expression in Inflammatory Bowel Disease Active, not recruiting NCT01171872
23 An Epidemiological Study of the Incidence of Inflammatory Bowel Disease in Spain Active, not recruiting NCT02686892
24 Short Versus Long Interval to Loop Ileostomy Reversal After Ileal Pouch Surgery in Patients With Ulcerative Colitis (SLIRPS) Trial Enrolling by invitation NCT03587519
25 Corrona Inflammatory Bowel Disease (IBD) Registry Enrolling by invitation NCT03162549
26 TARGET Registry A Project of the German Network for Intestinal Diseases in Cooperation With the German Association of Gastroenterologists in Private Practice (Bng) and Other Corporate Partners Not yet recruiting NCT04031482

Search NIH Clinical Center for Undetermined Colitis

Genetic Tests for Undetermined Colitis

Anatomical Context for Undetermined Colitis

MalaCards organs/tissues related to Undetermined Colitis:

40
Colon, Bone, Liver, Skin, Testes, Endothelial, Neutrophil

Publications for Undetermined Colitis

Articles related to Undetermined Colitis:

(show top 50) (show all 721)
# Title Authors PMID Year
1
Rectal stump management in inflammatory bowel disease: a cohort study, systematic review and proportional analysis of perioperative complications. 61
32236745 2020
2
Conditional Survival After IPAA for Ulcerative and Indeterminate Colitis: Does Long-term Pouch Survival Improve or Worsen With Time? 61
32243352 2020
3
A cross-sectional survey on the psychological impact of the COVID-19 pandemic on inflammatory bowel disease patients in Saudi Arabia. 61
32567580 2020
4
Isoflavones and inflammatory bowel disease. 61
32548137 2020
5
Pulmonary Manifestations in Adolescents With Inflammatory Bowel Disease. 61
32146830 2020
6
Malnutrition and quality of life among adult inflammatory bowel disease patients. 61
32514453 2020
7
Systematic Review: Psychosocial Correlates of Pain in Pediatric Inflammatory Bowel Disease. 61
32458966 2020
8
Toxicity profile of thiopurines in inflammatory bowel disease: a retrospective cohort analysis. 61
32548844 2020
9
Characteristics of Fecal Microbiota Transplantation Use in Inflammatory Bowel Disease Cohort. 61
32421761 2020
10
Inflammatory Bowel Disease in Children: Experience and Constraints in a Resource-limited Setting. 61
32483499 2020
11
Articular manifestations in patients with inflammatory bowel disease treated with vedolizumab. 61
32259251 2020
12
Usefulness of magnetic resonance enterography in the clinical decision-making process for patients with inflammatory bowel disease. 61
32349904 2020
13
Efficacy and safety of endoscopic balloon dilation in inflammatory bowel disease: results of the large multicenter study of the ENEIDA registry. 61
31144122 2020
14
The effect of diversion on readmission following ileal pouch-anal anastomosis in children. 61
31818436 2020
15
Treatment Adherence in Inflammatory Bowel Disease Patients from Argentina: A Multicenter Study. 61
32411197 2020
16
Nutritional status and body composition in children with inflammatory bowel disease: a prospective, controlled, and longitudinal study. 61
31919419 2020
17
Outcome of Ileal Pouch Anal Anastomosis in Patients with Indeterminate Colitis: A Systematic Review and Meta-analysis. 61
31912129 2020
18
Is diverting loop ileostomy necessary for completion proctectomy with ileal pouch-anal anastomosis? A multicenter randomized trial of the GETAID Chirurgie group (IDEAL trial): rationale and design (NCT03872271). 61
31830976 2019
19
Efficacy of Fecal Microbiota Transplantation for Recurrent C. Difficile Infection in Inflammatory Bowel Disease. 61
31821444 2019
20
Presentation and outcomes among inflammatory bowel disease patients with concurrent pneumatosis intestinalis: a case series and systematic review. 61
31671928 2019
21
Allergic and Immunologic Perspectives of Inflammatory Bowel Disease. 61
29754190 2019
22
Altering the Traditional Approach to Restorative Proctocolectomy After Subtotal Colectomy in Pediatric Patients. 61
31408401 2019
23
The Incidence and Definition of Crohn's Disease of the Pouch: A Systematic Review and Meta-analysis. 61
30698715 2019
24
RNase-L Deficiency-Associated Intractable Indeterminate Colitis in Children. 61
31077295 2019
25
Comparison of the use of wireless capsule endoscopy with magnetic resonance enterography in children with inflammatory bowel disease. 61
31391775 2019
26
Microscopic/"Backwash" Ileitis and Its Association With Colonic Disease in New Onset Pediatric Ulcerative Colitis. 61
31124991 2019
27
Colectomies in children with inflammatory bowel disease: a national referral centre experience. 61
30847603 2019
28
Impact of anti-TNF-alpha therapy on colectomy rate and indications for colectomy in ulcerative colitis: comparison of two patient cohorts from 2005 to 2007 and from 2014 to 2016. 61
31136207 2019
29
Ileal Pouch Excision: A Contemporary Observational Cohort. 61
30451759 2019
30
Analysis of DNA Methylation at Specific Loci in Stool Samples Detects Colorectal Cancer and High-Grade Dysplasia in Patients With Inflammatory Bowel Disease. 61
29775793 2019
31
Reporting Colonic Biopsies in Patients With Inflammatory Bowel Disease; a Practical Approach. 61
30256953 2019
32
The Relationship Between Sleep Disturbance and Disease Activity in Pediatric Patients With Inflammatory Bowel Disease. 61
30256267 2019
33
Vedolizumab Drug Level Correlation With Clinical Remission, Biomarker Normalization, and Mucosal Healing in Inflammatory Bowel Disease. 61
30165638 2019
34
A Comprehensive Approach to Pouch Disorders. 61
30124882 2019
35
Probiotics for inflammatory bowel diseases: a promising adjuvant treatment. 61
29804478 2019
36
Colon Surgery Risk With Corticosteroids Versus Immunomodulators or Biologics in Inflammatory Bowel Disease Patients With Clostridium difficile Infection. 61
30260451 2019
37
Microscopic / "Backwash" Ileitis and its Association with Colonic Disease in New Onset Pediatric Ulcerative Colitis. 61
30676522 2019
38
The Human Mesenteric Lymph Node Microbiome Differentiates Between Crohn's Disease and Ulcerative Colitis. 61
30239655 2019
39
Influence of Crohn's disease related polymorphisms in innate immune function on ileal microbiome. 61
30818349 2019
40
Disseminated tuberculosis and hemophagocytic syndrome although TB prophylaxis in patients with inflammatory bowel disease treated with Infliximab. 61
31024797 2019
41
Diagnostic Radiation Exposure in Patients with Inflammatory Bowel Disease. 61
31281802 2019
42
Inflammatory Bowel Disease Registry and Monitoring: Feasibility Study and Application (Isfahan Inflammatory Bowel Disease Surveillance Project). 61
31807260 2019
43
Incidence and predictors of new persistent opioid use following inflammatory bowel disease flares treated with oral corticosteroids. 61
30430615 2019
44
Refractory inflammatory bowel disease: is there a role for Epstein-Barr virus? A case-controlled study using highly sensitive Epstein-Barr virus-encoded small RNA1 in situ hybridization. 61
30120969 2018
45
Robotic-assisted subtotal colectomy for synchronous colon cancers in a patient with indeterminate colitis - a video vignette. 61
30238595 2018
46
Change of treatment modalities over the last 10 years in pediatric patients with inflammatory bowel disease in Switzerland. 61
29985208 2018
47
Influences and Impact of Anxiety and Depression in the Setting of Inflammatory Bowel Disease. 61
29788469 2018
48
Outcome of Cytomegalovirus Colitis in Inflammatory Bowel Disease with Different Regimes of Ganciclovir. 61
31049169 2018
49
Identification of Candidate Biomarkers Associated with Response to Vedolizumab in Inflammatory Bowel Disease. 61
29372476 2018
50
Revisional and Reconstructive Surgery for Failing IPAA is Associated with Good Function and Pouch Salvage in Highly Selected Patients. 61
29944583 2018

Variations for Undetermined Colitis

Expression for Undetermined Colitis

Search GEO for disease gene expression data for Undetermined Colitis.

Pathways for Undetermined Colitis

GO Terms for Undetermined Colitis

Sources for Undetermined Colitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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