MCID: UND001
MIFTS: 33

Undifferentiated Embryonal Sarcoma of the Liver

Categories: Cancer diseases, Fetal diseases, Liver diseases, Rare diseases

Aliases & Classifications for Undifferentiated Embryonal Sarcoma of the Liver

MalaCards integrated aliases for Undifferentiated Embryonal Sarcoma of the Liver:

Name: Undifferentiated Embryonal Sarcoma of the Liver 60
Undifferentiated Sarcoma of the Liver 60
Embryonal Sarcoma of the Liver 60
Ues 60

Classifications:

Orphanet: 60  
Rare hepatic diseases


External Ids:

Orphanet 60 ORPHA178315

Summaries for Undifferentiated Embryonal Sarcoma of the Liver

MalaCards based summary : Undifferentiated Embryonal Sarcoma of the Liver, also known as undifferentiated sarcoma of the liver, is related to histiocytoma and malignant fibroxanthoma. An important gene associated with Undifferentiated Embryonal Sarcoma of the Liver is CDK4 (Cyclin Dependent Kinase 4), and among its related pathways/superpathways are Retinoblastoma (RB) in Cancer and Regulation of nuclear SMAD2/3 signaling. Affiliated tissues include liver, kidney and brain.

Related Diseases for Undifferentiated Embryonal Sarcoma of the Liver

Diseases related to Undifferentiated Embryonal Sarcoma of the Liver via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 81)
# Related Disease Score Top Affiliating Genes
1 histiocytoma 29.8 MDM2 MYOD1 SERPINA3
2 malignant fibroxanthoma 29.5 CDK4 MDM2 MYOD1 SERPINA3
3 embryonal sarcoma 29.4 CDK4 MALAT1 MDM2 MYOD1 MYOG PEG3
4 rhabdomyosarcoma 29.4 CDK4 MDM2 MYOD1 MYOG
5 sarcoma 11.1
6 spindle cell sarcoma 10.6
7 congenital heart defects, hamartomas of tongue, and polysyndactyly 10.2
8 liposarcoma 10.2 CDK4 MDM2
9 ring chromosome 7 10.2 CDK4 MDM2
10 infiltrating angiolipoma 10.2 CDK4 MDM2
11 spindle cell lipoma 10.2 CDK4 MDM2
12 cellular myxoid liposarcoma 10.2 CDK4 MDM2
13 myxoid liposarcoma 10.2 CDK4 MDM2
14 lipoblastoma 10.2 CDK4 MDM2
15 helicobacter pylori infection 10.2
16 pemphigus foliaceus 10.2
17 laryngitis 10.2
18 dysphagia 10.2
19 bone osteosarcoma 10.2 CDK4 MDM2
20 atypical lipomatous tumor 10.2 CDK4 MDM2
21 mixed liposarcoma 10.2 CDK4 MDM2
22 periosteal chondrosarcoma 10.2 CDK4 MDM2
23 chondroid lipoma 10.2 CDK4 MDM2
24 periosteal osteogenic sarcoma 10.1 CDK4 MDM2
25 ischemic fasciitis 10.1 CDK4 MDM2
26 well-differentiated liposarcoma 10.1 CDK4 MDM2
27 dedifferentiated liposarcoma 10.1 CDK4 MDM2
28 small cell sarcoma 10.1 CDK4 MDM2
29 infiltrating lipoma 10.1 CDK4 MDM2
30 juxtacortical osteosarcoma 10.1 CDK4 MDM2
31 peripheral osteosarcoma 10.1 CDK4 MDM2
32 lipomatosis, multiple 10.1 CDK4 MDM2
33 retinal cancer 10.1 CDK4 MDM2
34 systemic lupus erythematosus 10.1
35 fibrous histiocytoma 10.1
36 appendicitis 10.1
37 lupus erythematosus 10.1
38 hypereosinophilic syndrome 10.1
39 undifferentiated pleomorphic sarcoma 10.1
40 mesenchymoma 10.1 MDM2 MYOD1
41 ocular cancer 10.0 CDK4 MDM2
42 breast rhabdomyosarcoma 10.0 MYOD1 MYOG
43 gallbladder sarcoma 10.0 MYOD1 MYOG
44 grade iii astrocytoma 10.0 CDK4 MDM2
45 inflammatory leiomyosarcoma 10.0 MYOD1 MYOG
46 testicular yolk sac tumor 10.0 MDM2 SERPINA3
47 conventional leiomyosarcoma 10.0 MYOD1 MYOG
48 schizencephaly 10.0
49 kidney disease 10.0
50 achalasia 10.0

Graphical network of the top 20 diseases related to Undifferentiated Embryonal Sarcoma of the Liver:



Diseases related to Undifferentiated Embryonal Sarcoma of the Liver

Symptoms & Phenotypes for Undifferentiated Embryonal Sarcoma of the Liver

Drugs & Therapeutics for Undifferentiated Embryonal Sarcoma of the Liver

Search Clinical Trials , NIH Clinical Center for Undifferentiated Embryonal Sarcoma of the Liver

Genetic Tests for Undifferentiated Embryonal Sarcoma of the Liver

Anatomical Context for Undifferentiated Embryonal Sarcoma of the Liver

MalaCards organs/tissues related to Undifferentiated Embryonal Sarcoma of the Liver:

42
Liver, Kidney, Brain, Smooth Muscle, Adrenal Gland, Tongue, Skeletal Muscle

Publications for Undifferentiated Embryonal Sarcoma of the Liver

Articles related to Undifferentiated Embryonal Sarcoma of the Liver:

(show top 50) (show all 102)
# Title Authors Year
1
Undifferentiated Embryonal Sarcoma of the Liver (UESL) in Adolescents: An Unexpected Diagnosis. ( 29702542 )
2019
2
Undifferentiated embryonal sarcoma of the liver in elderly: Case report and review of the literature. ( 30706877 )
2019
3
Undifferentiated Embryonal Sarcoma of the Liver: a Great Masquerader. ( 30714072 )
2019
4
Undifferentiated embryonal sarcoma of the liver mimicking venolymphatic malformation. ( 31011382 )
2019
5
Hanging Undifferentiated Embryonal Sarcoma of the Liver in Adult: an Unusual Presentation of an Aggressive Tumor. ( 29779073 )
2018
6
Undifferentiated embryonal sarcoma of the liver in adult patient: A report of two cases. ( 30215049 )
2018
7
Pulmonary Metastases from an Undifferentiated Embryonal Sarcoma of the Liver: A Case Report and Review. ( 30254779 )
2018
8
Undifferentiated Embryonal Sarcoma of the Liver in an Adult Patient. ( 30258736 )
2018
9
Characteristics and outcomes in children with undifferentiated embryonal sarcoma of the liver: A report from the National Cancer Database. ( 27781381 )
2017
10
A case of adult undifferentiated embryonal sarcoma of the liver successfully treated with right trisectionectomy: a case report. ( 28144858 )
2017
11
Undifferentiated embryonal sarcoma of the liver in a child: A whole exome sequencing analysis. ( 28539230 )
2017
12
Unresectable Undifferentiated Embryonal Sarcoma of the Liver in an Adult Male Treated with Chemotherapy and Orthotopic Liver Transplantation. ( 29226049 )
2017
13
Undifferentiated Embryonal Sarcoma of the Liver (UESL): A Single-Center Experience and Review of the Literature. ( 26925712 )
2016
14
Undifferentiated embryonal sarcoma of the liver with an unusual presentation: case report and review of the literature. ( 27034807 )
2016
15
Undifferentiated embryonal sarcoma of the liver in an adult patient. ( 27377912 )
2016
16
A single-center experience with undifferentiated embryonal sarcoma of the liver. ( 27427850 )
2016
17
The Role of Liver Transplantation in Undifferentiated Embryonal Sarcoma of the Liver in Children. ( 27438021 )
2016
18
Imaging features of undifferentiated embryonal sarcoma of the liver: a series of 15 children. ( 27562247 )
2016
19
Undifferentiated embryonal sarcoma of the liver in a young female: treatment with portal vein embolization and liver trisectonectomy. ( 27621753 )
2016
20
Repeated hepatic resections and radio-frequency ablations may improve the survival of adult undifferentiated embryonal sarcoma of the liver: report of two cases. ( 26366352 )
2015
21
Pre-operatively misdiagnosed undifferentiated embryonal sarcoma of the liver: analysis of 16 cases. ( 26807408 )
2015
22
Undifferentiated embryonal sarcoma of the liver: a concise review. ( 25611111 )
2015
23
Diagnosis and therapy of primary undifferentiated embryonal sarcoma of the liver. ( 24762610 )
2014
24
Remarkable regression of a lung recurrence from an undifferentiated embryonal sarcoma of the liver treated with a DC vaccine combined with immune cells: a case report. ( 25038546 )
2014
25
Undifferentiated embryonal sarcoma of the liver mistaken for hepatic abscess in an adult. ( 25120683 )
2014
26
A case of an undifferentiated embryonal sarcoma of the liver mimicking a liver abscess. ( 25364566 )
2014
27
Primary undifferentiated embryonal sarcoma of the liver misdiagnosed as hydatid cyst in a child: a case report and review of the literature. ( 25603636 )
2014
28
A Rare Case of Childhood Undifferentiated Embryonal Sarcoma of the Liver Managed Successfully. ( 26157829 )
2014
29
Undifferentiated embryonal sarcoma of the liver in a child: A case report and review of the literature. ( 23426588 )
2013
30
Undifferentiated embryonal sarcoma of the liver with focal osteoid picture-a case report. ( 24054758 )
2013
31
Undifferentiated embryonal sarcoma of the liver in a middle-aged adult with systemic lupus erythematosus. ( 24073982 )
2013
32
Management of undifferentiated embryonal sarcoma of the liver in children: a case series and management review. ( 24079623 )
2013
33
Characterization of translocations in mesenchymal hamartoma and undifferentiated embryonal sarcoma of the liver. ( 24120702 )
2013
34
Treatment of undifferentiated embryonal sarcoma of the liver in children--single center experience. ( 24210186 )
2013
35
Radiologic-pathologic comparison of undifferentiated embryonal sarcoma of the liver in a 61-year-old woman. ( 22421287 )
2012
36
Molecular cytogenetic characterization of undifferentiated embryonal sarcoma of the liver: a case report and literature review. ( 22551002 )
2012
37
Undifferentiated embryonal sarcoma of the liver in an adult patient: case report. ( 22798120 )
2012
38
An undifferentiated embryonal sarcoma of the liver containing adipophilin-positive vesicles in an adult with massive sinusoidal invasion. ( 23071865 )
2012
39
Rare case of adult undifferentiated (embryonal) sarcoma of the liver treated with liver transplantation: excellent long-term survival. ( 25374706 )
2012
40
Undifferentiated embryonal sarcoma of the liver is associated with mesenchymal hamartoma and multiple chromosomal abnormalities: a review of eleven cases. ( 20925497 )
2011
41
Undifferentiated embryonal sarcoma of the liver presenting as a hemorrhagic cystic tumor in an adult. ( 22146632 )
2011
42
Diffuse membranous immunoreactivity of CD56 and paranuclear dot-like staining pattern of cytokeratins AE1/3, CAM5.2, and OSCAR in undifferentiated (embryonal) sarcoma of the liver. ( 19809302 )
2010
43
Fine needle aspiration cytology of undifferentiated embryonal sarcoma of the liver. ( 20105209 )
2010
44
Adult primary undifferentiated embryonal sarcoma of the liver: a case report. ( 20137381 )
2010
45
Paradoxical hepatic tumor: Undifferentiated embryonal sarcoma of the liver. ( 20352000 )
2010
46
Primary undifferentiated embryonal sarcoma of the liver mistaken for hydatid disease. ( 20615265 )
2010
47
Undifferentiated (embryonal) sarcoma of the liver: an intriguing diagnosis in a child. ( 19242910 )
2009
48
Resection of a large, ruptured, undifferentiated (embryonal) sarcoma of the liver in a child: a case report and review of the literature. ( 19278169 )
2009
49
F-18 FDG PET/CT findings in a case of undifferentiated embryonal sarcoma of the liver with lung and adrenal gland metastasis in a child. ( 19352266 )
2009
50
Diagnosis of undifferentiated embryonal sarcoma of the liver-importance of combined studies of ultrasound and CT scan. ( 19770684 )
2009

Variations for Undifferentiated Embryonal Sarcoma of the Liver

Expression for Undifferentiated Embryonal Sarcoma of the Liver

Search GEO for disease gene expression data for Undifferentiated Embryonal Sarcoma of the Liver.

Pathways for Undifferentiated Embryonal Sarcoma of the Liver

Pathways related to Undifferentiated Embryonal Sarcoma of the Liver according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.35 CDK4 MDM2
2 11.25 CDK4 MYOD1
3 11.18 CDK4 MDM2
4 11 MDM2 MYOD1
5 10.82 CDK4 MDM2
6 10.6 CDK4 MDM2
7 10.13 CDK4 MDM2

GO Terms for Undifferentiated Embryonal Sarcoma of the Liver

Cellular components related to Undifferentiated Embryonal Sarcoma of the Liver according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription factor complex GO:0005667 8.8 CDK4 MYOD1 MYOG

Biological processes related to Undifferentiated Embryonal Sarcoma of the Liver according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 cellular response to growth factor stimulus GO:0071363 9.55 MDM2 MYOG
2 positive regulation of cell cycle GO:0045787 9.54 CDK4 MDM2
3 skeletal muscle tissue development GO:0007519 9.52 MYOD1 MYOG
4 skeletal muscle cell differentiation GO:0035914 9.51 MYOD1 MYOG
5 cellular response to estradiol stimulus GO:0071392 9.49 MYOD1 MYOG
6 positive regulation of muscle cell differentiation GO:0051149 9.48 MYOD1 MYOG
7 skeletal muscle fiber development GO:0048741 9.46 MYOD1 MYOG
8 negative regulation of cell cycle arrest GO:0071157 9.43 CDK4 MDM2
9 positive regulation of myoblast differentiation GO:0045663 9.4 MYOD1 MYOG
10 myoblast differentiation GO:0045445 9.37 MYOD1 MYOG
11 positive regulation of myoblast fusion GO:1901741 9.32 MYOD1 MYOG
12 myotube differentiation GO:0014902 9.26 MYOD1 MYOG
13 positive regulation of skeletal muscle fiber development GO:0048743 9.16 MYOD1 MYOG
14 muscle cell fate commitment GO:0042693 8.96 MYOD1 MYOG
15 regulation of gene expression GO:0010468 8.92 CDK4 MDM2 MYOD1 PEG3

Molecular functions related to Undifferentiated Embryonal Sarcoma of the Liver according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromatin DNA binding GO:0031490 8.96 MYOD1 MYOG
2 E-box binding GO:0070888 8.62 MYOD1 MYOG

Sources for Undifferentiated Embryonal Sarcoma of the Liver

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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