MCID: URC005
MIFTS: 25

Urachal Cyst

Categories: Cancer diseases, Fetal diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Urachal Cyst

MalaCards integrated aliases for Urachal Cyst:

Name: Urachal Cyst 20 58 6

Characteristics:

Orphanet epidemiological data:

58
urachal cyst
Inheritance: Not applicable;

Classifications:

Orphanet: 58  
Rare renal diseases
Developmental anomalies during embryogenesis


External Ids:

MESH via Orphanet 45 D014496
ICD10 via Orphanet 33 Q64.4
UMLS via Orphanet 72 C0041915
Orphanet 58 ORPHA488

Summaries for Urachal Cyst

GARD : 20 A urachal cyst is a sac-like pocket of tissue that develops in the urachus, a primitive structure that connects the umbilical cord to the bladder in the developing baby. Although it normally disappears prior to birth, part of the urachus may remain in some people. Urachal cysts can develop at any age, but typically affect older children and adults. Urachal cysts are often not associated with any signs or symptoms unless there are complications such as infection. In these cases, symptoms may include abdominal pain, fever, pain with urination and/or hematuria. Urachal cysts may be monitored, or they may be treated with surgery to drain the cyst and/or remove the urachus.

MalaCards based summary : Urachal Cyst is related to peritonitis and appendicitis. An important gene associated with Urachal Cyst is XDH (Xanthine Dehydrogenase). Affiliated tissues include small intestine, colon and appendix.

Wikipedia : 74 A urachal cyst is a sinus remaining from the allantois during embryogenesis. It is a cyst which occurs... more...

Related Diseases for Urachal Cyst

Diseases related to Urachal Cyst via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 61)
# Related Disease Score Top Affiliating Genes
1 peritonitis 10.5
2 appendicitis 10.4
3 patent urachus 10.4
4 urachal sinus 10.3
5 umbilical hernia 10.3
6 cystitis 10.3
7 urachal diverticulum 10.3
8 transitional cell carcinoma 10.2
9 urinary tract infection 10.1
10 anuria 10.1
11 mucinous adenocarcinoma 10.1
12 pseudomyxoma peritonei 10.1
13 appendix adenocarcinoma 10.1
14 intestinal obstruction 10.1
15 urachal cancer 10.1
16 hydronephrosis 10.1
17 acute cystitis 10.1
18 bile duct cancer 10.1
19 urachal adenocarcinoma 10.1
20 meckel diverticulum 9.9
21 down syndrome 9.9
22 renal hypodysplasia/aplasia 1 9.9
23 vesicoureteral reflux 1 9.9
24 prostatic hyperplasia, benign 9.9
25 diabetes mellitus, ketosis-prone 9.9
26 abdominal tuberculosis 9.9
27 villous adenoma 9.9
28 bladder exstrophy 9.9
29 paragonimiasis 9.9
30 prostatic hypertrophy 9.9
31 alcoholic hepatitis 9.9
32 leiomyoma 9.9
33 pyuria 9.9
34 prostatitis 9.9
35 urinary system disease 9.9
36 constipation 9.9
37 cystadenoma 9.9
38 benign mesothelioma 9.9
39 prostatic adenoma 9.9
40 adenocarcinoma 9.9
41 acute kidney failure 9.9
42 teratoma 9.9
43 bladder adenocarcinoma 9.9
44 placental insufficiency 9.9
45 bladder urothelial carcinoma 9.9
46 urinary tract obstruction 9.9
47 clear cell adenofibroma 9.9
48 cystadenofibroma 9.9
49 juvenile rheumatoid arthritis 9.9
50 ovarian serous cystadenofibroma 9.9

Graphical network of the top 20 diseases related to Urachal Cyst:



Diseases related to Urachal Cyst

Symptoms & Phenotypes for Urachal Cyst

Drugs & Therapeutics for Urachal Cyst

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Umbilical Pilonidal Sinus: an Underestimated and Little-known Clinical Entity - Report of Two Cases Completed NCT03007173

Search NIH Clinical Center for Urachal Cyst

Genetic Tests for Urachal Cyst

Anatomical Context for Urachal Cyst

MalaCards organs/tissues related to Urachal Cyst:

40
Small Intestine, Colon, Appendix

Publications for Urachal Cyst

Articles related to Urachal Cyst:

(show top 50) (show all 326)
# Title Authors PMID Year
1
Current diagnosis and management of urachal remnants. 20 61
24094971 2013
2
[Infected urachal cyst in an adult manifests as urosepsis]. 61
32219774 2021
3
A Large Abdominal Mass in a Child Presenting with Fever and Urinary Symptoms: An Infected Urachal Cyst. 61
32882259 2021
4
Gossypiboma with perforation of the umbilicus mimicking a complicated urachal cyst: a case report. 61
33069217 2020
5
Demographics and baseline care among newly transitioning adult congenital urology patients. 61
32593616 2020
6
Urinary bladder rupture years after excision of urachal remnant. 61
33100570 2020
7
The urachus revisited: multimodal imaging of benign & malignant urachal pathology. 61
32045264 2020
8
Acute Presentation of Urachal Cyst: A Case Report. 61
32582481 2020
9
Urachal cyst. 61
32124848 2020
10
Unexpected finding of urachal remnant cyst. Tips for laparoscopic approach. 61
33039342 2020
11
An infected urachal cyst presenting as acute abdominal pain in a child: A case report. 61
32000391 2020
12
Inflammatory pseudotumor secondary to urachal cyst: A challenging clinical case report. 61
31927401 2020
13
Imaging of urachal anomalies. 61
31478084 2019
14
Umbilical reconstruction: different techniques, a single aim. 61
31910176 2019
15
The primary considerations and image guided diagnosis of an infected urachal cyst in a pediatric patient. 61
31372192 2019
16
Infected urachal cyst in an adult: A case report. 61
31380223 2019
17
Ultrasound findings of urachal anomalies. A series of interesting cases. 61
31476210 2019
18
Surgical strategy of urachal remnants in children. 61
31384429 2019
19
Acute abdomen due to an infected urachal cyst in a 5-year-old female: case report. 61
31139338 2019
20
An Infected Urachal Cyst in a 4-Year-Old Girl Presenting with Recurrent Abdominal Pain. 61
30879848 2019
21
Management of symptomatic urachal cysts in children. 61
30666029 2019
22
Surgical management for an infected urachal cyst in an adult: Case report and literature review. 61
30959359 2019
23
Cured by Da Vinci Xi: meticulous dissection of an infected urachal cyst presenting with lower urinary tract symptoms in an adult. 61
30591831 2018
24
Urachal Remnants in Patients Presenting to the Emergency Department with Abdominal Pain. 61
30072186 2018
25
[A Case of Urachal Carcinoma Treated with Laparoscopic Resection of Urachal Remnants with Partial Cystectomy that was Difficult to Diagnose Preoperatively by Transurethral Biopsy]. 61
30369224 2018
26
Prolapsed bladder following rupture of patent urachal cyst, mimicking bladder exstrophy: a case report and literature review. 61
29318419 2018
27
Sonographic detection of an infected maternal urachal cyst during pregnancy. 61
28980334 2018
28
Urachal cyst with xanthogranulomatous cystitis: A rare case report. 61
29719338 2018
29
Malignant transformation of a urachal cyst-a case report and literature review. 61
30271532 2018
30
Laparoscopic treatment of an infected urachalcyst and diverticulum in a young adult: Presentation of a case and review of the literature. 61
29966956 2018
31
Urachal Cyst Diagnosed by Point-of-care Ultrasound. 61
29849381 2017
32
[Acute Kidney Failure Due to Urachal Cyst?] 61
28278526 2017
33
Computed tomography localization of the appendix in the pediatric population relative to the lumbar spine. 61
28091700 2017
34
Laparoscopy for Differential Diagnosis and Treatment of a Rarely Remembered Cause of Acute Inflammatory Abdomen in Women: Urachal Cyst Abscess. 61
28343546 2017
35
"Look Before You Leap": Urachal Mass in Adults. 61
28983381 2017
36
[Delayed umbilical cord separation]. 61
29241465 2017
37
Single-Incision Laparoscopy Surgery Excision of an Infected Urachal Cyst: Description of the Technique. 61
28164161 2017
38
Urachal Cyst, Meckel's Diverticulum and Band, and Urachus. 61
28164005 2017
39
Robotic surgery in pediatric urology. 61
29264208 2017
40
Infected Urachal Cyst. 61
28029928 2016
41
Laparoscopic management of urachal cysts. 61
27867852 2016
42
Urachal-sigmoid fistula managed by laparoscopic assisted high anterior resection, primary anastomosis and en bloc resection of the urachal cyst and involved bladder. 61
27217193 2016
43
An umbilical surprise: a collective review on umbilical pilonidal sinus : An uncommon alternative diagnosis in common umbilical symptoms. 61
27193004 2016
44
Infected Urachal Cyst in an Adult: A Laparoscopic Approach. 61
27462196 2016
45
A Rare Urachal Cyst in a Case of Ketamine-induced Cystitis Provides Mechanistic Insights. 61
26743387 2016
46
Prenatal and Postnatal Clinical Course of an Urachus Identified as an Allantoic Cyst in the Umbilical Cord. 61
26981767 2016
47
Laparoendoscopic single site surgery in pediatric urology: does it require specialized tools? 61
27256182 2016
48
Diabetic Ketoacidosis Precipitated by Urachal Cyst Infection. 61
26432079 2016
49
Urachal Cyst Causing Small Bowel Obstruction in an Adult with a Virgin Abdomen. 61
27900227 2016
50
Cystoscopic light assisted mucosa sparing laparoscopic urachal cyst excision. 61
28127464 2016

Variations for Urachal Cyst

ClinVar genetic disease variations for Urachal Cyst:

6
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 XDH NM_000379.4(XDH):c.3647C>A (p.Pro1216His) SNV Uncertain significance 335760 rs143981573 2:31562482-31562482 2:31339616-31339616
2 XDH NM_000379.4(XDH):c.1172C>T (p.Pro391Leu) SNV Uncertain significance 598996 rs1558697792 2:31602803-31602803 2:31379937-31379937

Expression for Urachal Cyst

Search GEO for disease gene expression data for Urachal Cyst.

Pathways for Urachal Cyst

GO Terms for Urachal Cyst

Sources for Urachal Cyst

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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