MCID: URM001
MIFTS: 22

Uremic Neuropathy

Categories: Nephrological diseases, Neuronal diseases

Aliases & Classifications for Uremic Neuropathy

MalaCards integrated aliases for Uremic Neuropathy:

Name: Uremic Neuropathy 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:4675
NCIt 49 C27055
SNOMED-CT 67 11659006
UMLS 71 C0268708

Summaries for Uremic Neuropathy

MalaCards based summary : Uremic Neuropathy is related to polyneuropathy and uremia. An important gene associated with Uremic Neuropathy is PTH (Parathyroid Hormone). Affiliated tissues include heart, kidney and testes.

Related Diseases for Uremic Neuropathy

Diseases related to Uremic Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 50)
# Related Disease Score Top Affiliating Genes
1 polyneuropathy 30.0 PMP22 EPO B2M
2 uremia 29.9 PTH EPO B2M
3 peripheral nervous system disease 29.0 TRPM8 PMP22 EPO B2M ARHGEF10
4 neuropathy 10.8
5 end stage renal disease 10.2
6 osteitis fibrosa 10.2 PTH B2M
7 mineral metabolism disease 10.2 PTH B2M
8 tracheal calcification 10.1 PTH EPO
9 ulnar neuropathy 10.1 PMP22 ARHGEF10
10 calciphylaxis 10.1 PTH EPO
11 fanconi syndrome 10.1 PTH B2M
12 mononeuropathy 10.1 PMP22 ARHGEF10
13 charcot-marie-tooth disease, demyelinating, type 1a 10.1 PMP22 ARHGEF10
14 guillain-barre syndrome 10.1
15 kidney disease 10.1
16 paget's disease of bone 10.1 PTH B2M
17 renal osteodystrophy 10.0 PTH EPO
18 parathyroid gland disease 10.0 PTH EPO
19 blood protein disease 10.0 EPO B2M
20 carpal tunnel syndrome 10.0 PMP22 B2M
21 motor peripheral neuropathy 10.0 PMP22 ARHGEF10
22 restless legs syndrome 10.0
23 dysautonomia 10.0
24 paresthesia 10.0
25 hypophosphatemia 9.9 PTH B2M
26 secondary hyperparathyroidism 9.9 PTH EPO B2M
27 cystic kidney disease 9.9 PTH EPO B2M
28 urinary system disease 9.8 PTH EPO B2M
29 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 9.8
30 slowed nerve conduction velocity, autosomal dominant 9.8
31 microvascular complications of diabetes 3 9.8
32 microvascular complications of diabetes 4 9.8
33 microvascular complications of diabetes 6 9.8
34 microvascular complications of diabetes 7 9.8
35 graft-versus-host disease 9.8
36 osteonecrosis 9.8
37 autonomic neuropathy 9.8
38 pericarditis 9.8
39 impotence 9.8
40 constipation 9.8
41 myopathy 9.8
42 chronic inflammatory demyelinating polyradiculoneuropathy 9.8
43 demyelinating polyneuropathy 9.8
44 muscular atrophy 9.8
45 encephalopathy 9.8
46 bone disease 9.8 PTH EPO B2M
47 nerve compression syndrome 9.7 PTH PMP22 B2M ARHGEF10
48 chronic kidney disease 9.6 PTH EPO B2M
49 diabetic neuropathy 9.5 TRPM8 PMP22 EPO
50 myeloma, multiple 9.4 PTH EPO B2M

Graphical network of the top 20 diseases related to Uremic Neuropathy:



Diseases related to Uremic Neuropathy

Symptoms & Phenotypes for Uremic Neuropathy

Drugs & Therapeutics for Uremic Neuropathy

Search Clinical Trials , NIH Clinical Center for Uremic Neuropathy

Genetic Tests for Uremic Neuropathy

Anatomical Context for Uremic Neuropathy

MalaCards organs/tissues related to Uremic Neuropathy:

40
Heart, Kidney, Testes

Publications for Uremic Neuropathy

Articles related to Uremic Neuropathy:

(show top 50) (show all 142)
# Title Authors PMID Year
1
Acute Fulminant Uremic Neuropathy Following Coronary Angiography Mimicking Guillain Barre Syndrome. 61
31562732 2019
2
Uremic neuropathy: an overview of the current literature. 61
30994849 2019
3
Uremic neuropathy: an overview of the current literature. 61
30892456 2019
4
The role of urea in neuronal degeneration and sensitization: An in vitro model of uremic neuropathy. 61
31549574 2019
5
A Clinical and Electrophysiological Study of Peripheral Neuropathies in Predialysis and Dialysis Patients: Our Experience from South India. 61
31331132 2018
6
Acute Fulminant Uremic Neuropathy Following Coronary Angiography Mimicking Guillain-Barre Syndrome. 61
28706599 2017
7
Impact of nocturnal hemodialysis on peripheral uremic neuropathy. 61
26264143 2015
8
Identifying Common Genetic Risk Factors of Diabetic Neuropathies. 61
26074879 2015
9
Chronic renal disease progression: treatment strategies and potassium intake. 61
23953806 2013
10
Uremic neuropathy. 61
23931805 2013
11
A community-based epidemiological study of peripheral neuropathies in Assiut, Egypt. 61
23146298 2012
12
Rapid reversal of uremic neuropathy following renal transplantation in an adolescent. 61
22188489 2012
13
The prevalence of peripheral neuropathy in hemodialysis patients. 61
22595389 2012
14
Exploring the potential of flunarizine for Cisplatin-induced painful uremic neuropathy in rats. 61
22087421 2011
15
A case of end-stage renal disease initially manifested with visual loss caused by uremic optic neuropathy. 61
21624044 2011
16
A case of an accelerated uremic neuropathy. 61
21401366 2011
17
[Electrophysiological diagnosis of severe carpal tunnel syndrome in patients on maintenance hemodialysis with created arterio-venous fistula and concomitant polyneuropathy]. 61
20687372 2010
18
[Uremic pruritus: an unresolved challenge]. 61
19802804 2009
19
Autonomic neuropathy in hemodialysis patients: questionnaires versus clinical tests. 61
19153803 2009
20
Clinical course of uremic neuropathy in long-term hemodialysis. 61
18982751 2008
21
Nerve conduction studies and prediction of mortality in hemodialysis patients. 61
18704818 2008
22
Uremic neuropathy: clinical features and new pathophysiological insights. 61
17195171 2007
23
Neurophysiologic changes in live related kidney transplant children and adolescents. 61
16176413 2005
24
Association between carpel tunnel syndrome and arteriovenous fistula in hemodialysis patients. 61
16079682 2005
25
Severe proximal myopathy in advanced renal failure. Diagnosis and management. 61
15977450 2004
26
Effect of propranolol on heart rate variability in patients with end-stage renal disease: a double-blind, placebo-controlled, randomized crossover pilot trial. 61
15182126 2004
27
Effect of erythropoietin therapy on polyneuropathy in predialytic patients. 61
12649543 2003
28
Neurophysiologic parameters and symptoms in chronic renal failure. 61
12115978 2002
29
[Uremic neuropathy is more frequent in male patients]. 61
11865591 2001
30
Uremic neuropathy and the analysis of electrophysiological changes. 61
11284054 2001
31
[Uremic neuropathy, uremic encephalopathy]. 61
11057310 2000
32
Improvement of uremic autonomic dysfunction after renal transplantation: a heart rate variability study. 61
9730704 1998
33
[Uremic neuropathy--II. Is pruritus in dialyzed patients related to neuropathy?]. 61
10085700 1998
34
Features of uremic neuropathy in long-term dialysis. 61
10097427 1998
35
[Uremic neuropathy--I. Is uremic neuropathy related to patient age, duration of nephropathy and dialysis treatment?]. 61
10085699 1998
36
Distinctive electrophysiological features of denervated muscle in uremic patients. 61
9458061 1997
37
[Non-uremic neuropathy in hemodialysis patients]. 61
9282368 1997
38
Reversible uremic deafness: is it correlated with the degree of anemia? 61
9153103 1997
39
[Uremic neuropathy]. 61
9277685 1997
40
Paradoxical heat sensation in uremic polyneuropathy. 61
7783767 1995
41
[Improvement of temperature and vibration sense in chronic uremia after a single dialysis]. 61
7672749 1995
42
Metabolic encephalopathy as a complication of renal failure: mechanisms and mediators. 61
7804801 1994
43
Accelerated neuropathy of renal failure. 61
8387770 1993
44
Heart rate variability. 61
8439119 1993
45
Morbidity and mortality of CAPD and hemodialysis. 61
8445838 1993
46
The function of large and small nerve fibers in renal failure. 61
1313545 1992
47
[Uremic neuropathy in chronic kidney failure with dialysis]. 61
1315886 1992
48
Ascorbic acid derivatives in two different fractions of uremic toxins. 61
1783448 1991
49
Uremic neuropathy. A case presentation. 61
1663549 1991
50
Nerve conduction studies and vibration perception thresholds in diabetic and uremic neuropathy. 61
1848989 1991

Variations for Uremic Neuropathy

Expression for Uremic Neuropathy

Search GEO for disease gene expression data for Uremic Neuropathy.

Pathways for Uremic Neuropathy

GO Terms for Uremic Neuropathy

Biological processes related to Uremic Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of neuron projection development GO:0010977 8.96 PMP22 B2M
2 response to cadmium ion GO:0046686 8.62 PTH B2M

Sources for Uremic Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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