MCID: URM001
MIFTS: 22

Uremic Neuropathy

Categories: Nephrological diseases, Neuronal diseases

Aliases & Classifications for Uremic Neuropathy

MalaCards integrated aliases for Uremic Neuropathy:

Name: Uremic Neuropathy 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:4675
NCIt 49 C27055
SNOMED-CT 67 11659006
UMLS 71 C0268708

Summaries for Uremic Neuropathy

MalaCards based summary : Uremic Neuropathy is related to polyneuropathy and uremia. An important gene associated with Uremic Neuropathy is PTH (Parathyroid Hormone). Affiliated tissues include heart, kidney and testes.

Related Diseases for Uremic Neuropathy

Diseases related to Uremic Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 50, show less)
# Related Disease Score Top Affiliating Genes
1 polyneuropathy 30.0 PMP22 EPO B2M
2 uremia 29.9 PTH EPO B2M
3 peripheral nervous system disease 29.0 TRPM8 PMP22 EPO B2M ARHGEF10
4 neuropathy 10.8
5 end stage renal disease 10.2
6 osteitis fibrosa 10.2 PTH B2M
7 mineral metabolism disease 10.2 PTH B2M
8 tracheal calcification 10.1 PTH EPO
9 ulnar neuropathy 10.1 PMP22 ARHGEF10
10 calciphylaxis 10.1 PTH EPO
11 fanconi syndrome 10.1 PTH B2M
12 mononeuropathy 10.1 PMP22 ARHGEF10
13 charcot-marie-tooth disease, demyelinating, type 1a 10.1 PMP22 ARHGEF10
14 guillain-barre syndrome 10.1
15 kidney disease 10.1
16 paget's disease of bone 10.1 PTH B2M
17 renal osteodystrophy 10.0 PTH EPO
18 parathyroid gland disease 10.0 PTH EPO
19 blood protein disease 10.0 EPO B2M
20 carpal tunnel syndrome 10.0 PMP22 B2M
21 motor peripheral neuropathy 10.0 PMP22 ARHGEF10
22 restless legs syndrome 10.0
23 dysautonomia 10.0
24 paresthesia 10.0
25 hypophosphatemia 9.9 PTH B2M
26 secondary hyperparathyroidism 9.9 PTH EPO B2M
27 cystic kidney disease 9.9 PTH EPO B2M
28 urinary system disease 9.8 PTH EPO B2M
29 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 9.8
30 slowed nerve conduction velocity, autosomal dominant 9.8
31 microvascular complications of diabetes 3 9.8
32 microvascular complications of diabetes 4 9.8
33 microvascular complications of diabetes 6 9.8
34 microvascular complications of diabetes 7 9.8
35 graft-versus-host disease 9.8
36 osteonecrosis 9.8
37 autonomic neuropathy 9.8
38 pericarditis 9.8
39 impotence 9.8
40 constipation 9.8
41 myopathy 9.8
42 chronic inflammatory demyelinating polyradiculoneuropathy 9.8
43 demyelinating polyneuropathy 9.8
44 muscular atrophy 9.8
45 encephalopathy 9.8
46 bone disease 9.8 PTH EPO B2M
47 nerve compression syndrome 9.7 PTH PMP22 B2M ARHGEF10
48 chronic kidney disease 9.6 PTH EPO B2M
49 diabetic neuropathy 9.5 TRPM8 PMP22 EPO
50 myeloma, multiple 9.4 PTH EPO B2M

Graphical network of the top 20 diseases related to Uremic Neuropathy:



Diseases related to Uremic Neuropathy

Symptoms & Phenotypes for Uremic Neuropathy

Drugs & Therapeutics for Uremic Neuropathy

Search Clinical Trials , NIH Clinical Center for Uremic Neuropathy

Genetic Tests for Uremic Neuropathy

Anatomical Context for Uremic Neuropathy

MalaCards organs/tissues related to Uremic Neuropathy:

40
Heart, Kidney, Testes

Publications for Uremic Neuropathy

Articles related to Uremic Neuropathy:

(showing 142, show less)
# Title Authors PMID Year
1
Acute Fulminant Uremic Neuropathy Following Coronary Angiography Mimicking Guillain Barre Syndrome. 61
31562732 2019
2
Uremic neuropathy: an overview of the current literature. 61
30994849 2019
3
Uremic neuropathy: an overview of the current literature. 61
30892456 2019
4
The role of urea in neuronal degeneration and sensitization: An in vitro model of uremic neuropathy. 61
31549574 2019
5
A Clinical and Electrophysiological Study of Peripheral Neuropathies in Predialysis and Dialysis Patients: Our Experience from South India. 61
31331132 2018
6
Acute Fulminant Uremic Neuropathy Following Coronary Angiography Mimicking Guillain-Barre Syndrome. 61
28706599 2017
7
Impact of nocturnal hemodialysis on peripheral uremic neuropathy. 61
26264143 2015
8
Identifying Common Genetic Risk Factors of Diabetic Neuropathies. 61
26074879 2015
9
Chronic renal disease progression: treatment strategies and potassium intake. 61
23953806 2013
10
Uremic neuropathy. 61
23931805 2013
11
A community-based epidemiological study of peripheral neuropathies in Assiut, Egypt. 61
23146298 2012
12
Rapid reversal of uremic neuropathy following renal transplantation in an adolescent. 61
22188489 2012
13
The prevalence of peripheral neuropathy in hemodialysis patients. 61
22595389 2012
14
Exploring the potential of flunarizine for Cisplatin-induced painful uremic neuropathy in rats. 61
22087421 2011
15
A case of end-stage renal disease initially manifested with visual loss caused by uremic optic neuropathy. 61
21624044 2011
16
A case of an accelerated uremic neuropathy. 61
21401366 2011
17
[Electrophysiological diagnosis of severe carpal tunnel syndrome in patients on maintenance hemodialysis with created arterio-venous fistula and concomitant polyneuropathy]. 61
20687372 2010
18
[Uremic pruritus: an unresolved challenge]. 61
19802804 2009
19
Autonomic neuropathy in hemodialysis patients: questionnaires versus clinical tests. 61
19153803 2009
20
Clinical course of uremic neuropathy in long-term hemodialysis. 61
18982751 2008
21
Nerve conduction studies and prediction of mortality in hemodialysis patients. 61
18704818 2008
22
Uremic neuropathy: clinical features and new pathophysiological insights. 61
17195171 2007
23
Neurophysiologic changes in live related kidney transplant children and adolescents. 61
16176413 2005
24
Association between carpel tunnel syndrome and arteriovenous fistula in hemodialysis patients. 61
16079682 2005
25
Severe proximal myopathy in advanced renal failure. Diagnosis and management. 61
15977450 2004
26
Effect of propranolol on heart rate variability in patients with end-stage renal disease: a double-blind, placebo-controlled, randomized crossover pilot trial. 61
15182126 2004
27
Effect of erythropoietin therapy on polyneuropathy in predialytic patients. 61
12649543 2003
28
Neurophysiologic parameters and symptoms in chronic renal failure. 61
12115978 2002
29
[Uremic neuropathy is more frequent in male patients]. 61
11865591 2001
30
Uremic neuropathy and the analysis of electrophysiological changes. 61
11284054 2001
31
[Uremic neuropathy, uremic encephalopathy]. 61
11057310 2000
32
Improvement of uremic autonomic dysfunction after renal transplantation: a heart rate variability study. 61
9730704 1998
33
[Uremic neuropathy--II. Is pruritus in dialyzed patients related to neuropathy?]. 61
10085700 1998
34
Features of uremic neuropathy in long-term dialysis. 61
10097427 1998
35
[Uremic neuropathy--I. Is uremic neuropathy related to patient age, duration of nephropathy and dialysis treatment?]. 61
10085699 1998
36
Distinctive electrophysiological features of denervated muscle in uremic patients. 61
9458061 1997
37
[Non-uremic neuropathy in hemodialysis patients]. 61
9282368 1997
38
Reversible uremic deafness: is it correlated with the degree of anemia? 61
9153103 1997
39
[Uremic neuropathy]. 61
9277685 1997
40
Paradoxical heat sensation in uremic polyneuropathy. 61
7783767 1995
41
[Improvement of temperature and vibration sense in chronic uremia after a single dialysis]. 61
7672749 1995
42
Metabolic encephalopathy as a complication of renal failure: mechanisms and mediators. 61
7804801 1994
43
Accelerated neuropathy of renal failure. 61
8387770 1993
44
Heart rate variability. 61
8439119 1993
45
Morbidity and mortality of CAPD and hemodialysis. 61
8445838 1993
46
The function of large and small nerve fibers in renal failure. 61
1313545 1992
47
[Uremic neuropathy in chronic kidney failure with dialysis]. 61
1315886 1992
48
Ascorbic acid derivatives in two different fractions of uremic toxins. 61
1783448 1991
49
Uremic neuropathy. A case presentation. 61
1663549 1991
50
Nerve conduction studies and vibration perception thresholds in diabetic and uremic neuropathy. 61
1848989 1991
51
Effect of hemodialysis and hemodiafiltration on uremic neuropathy. 61
1668062 1991
52
Restoration by biotin of the in vitro microtubule formation inhibited by uremic toxins. 61
2020347 1991
53
Circadian blood pressure variations under different pathophysiological conditions. 61
2095380 1990
54
Does ambulatory blood pressure monitoring improve the diagnosis of secondary hypertension? 61
2082001 1990
55
Axoplasmic electrolyte contents measured by X-ray microanalysis in experimental uremic neuropathy. 61
2174479 1990
56
[Neuroelectrophysiological study in patients on long-term hemodialysis]. 61
2160548 1990
57
[Myopathy in uremic patients]. 61
2187233 1990
58
Recovery of uremic neuropathy after renal transplantation. 61
2154362 1990
59
Esophageal dysfunction in chronic hemodialysis patients. 61
2392192 1990
60
Audiological findings in elderly patients with chronic renal failure. 61
2087980 1990
61
[Study of vibration sensation in the aspect of disorders of calcium-phosphate metabolism in patients with chronic renal failure]. 61
2642222 1989
62
Uremic neuropathy and treatment with renal transplantation. 61
2549887 1989
63
[Uremic neuropathy]. 61
2553356 1989
64
The effects of hemodialysis with different membranes on middle molecules and uremic neuropathy. 61
2538398 1989
65
Proximal vs. distal nerve conduction measurements in uremic neuropathy. 61
2854787 1988
66
Osteonecrosis of the femoral head after renal transplantation. Pathogenetic considerations. 61
3069464 1988
67
Nervous system complications in uremia. 61
2837930 1988
68
The natural history of uremic neuropathy. 61
2844471 1988
69
Rapid improvement of uremic neuropathy on short high-efficiency hemodialysis with special reference to middle molecules. 61
3675953 1987
70
Polymethylmethacrylate in chronic hemodialysis. Is it of benefit in patients with uremic neuropathy? 61
3675957 1987
71
Colchicine myopathy and neuropathy. 61
3035372 1987
72
Transplant osteonecrosis: can it be due to uremic neuropathy? 61
2821420 1987
73
Experimental studies on pathogenesis and progression of uremic neuropathy in rats. I. Development of chronic renal failure in rats. 61
3427261 1986
74
Experimental studies on pathogenesis and progression of uremic neuropathy in rats. II. Is plasma myoinositol a uremic neurotoxin? 61
3427262 1986
75
[The F-wave in uremic neuropathy]. 61
3022562 1986
76
[Uremic neuropathy. Clinical and neurophysiological data on patients on chronic hemodialysis treatment]. 61
3742981 1986
77
Inhibition of microtubule formation by uremic toxins: action mechanism and hypothesis about the active component. 61
3698354 1986
78
Vibratory perception threshold compared with nerve conduction velocity in the evaluation of uremic neuropathy. 61
4003031 1985
79
Thermal sensitivity in uremic neuropathy. 61
4003032 1985
80
Uremic polyneuropathy: different effects of hemodialysis and continuous ambulatory peritoneal dialysis. 61
4083083 1985
81
Evaluation of uremic neuropathy by visual (VEP) and brainstem auditory (BAEP) evoked potentials. 61
3837513 1985
82
Uremic neuropathy: clinical and neurophysiological investigation of dialysis patients using different chemical membranes. 61
4065159 1985
83
Experimental uremic neuropathy. Part 2. Sodium permeability decrease and inactivation in potential clamped nerve fibers. 61
6088705 1984
84
Experimental uremic neuropathy. Part 1. Decreased nerve conduction velocity in rats. 61
6470744 1984
85
Neuropathy in end-stage renal disease secondary to primary renal disease and diabetes. 61
6324717 1984
86
Control of uremic neuropathy by equilibrium peritoneal dialysis. 61
6329962 1984
87
Improvement of uremic neuropathy and hypogeusia by dialysate zinc supplementation: a double-blind study. 61
6330425 1983
88
Different patterns of uremic polyneuropathy: clinicopathologic study. 61
6682496 1983
89
Improved separation and quantification of the "middle molecule" b4-2 in uremia. 61
6831703 1983
90
[Gangliosides: a new prospective therapy of uremic neuropathy]. 61
6861458 1983
91
[Suggestion for a methodology for studying uremic neuropathy]. 61
6296929 1982
92
[Uremic neuropathy and the type of dialysis]. 61
6326249 1982
93
[Uremic neuropathy in diabetic nephropathy and primary nephropathy]. 61
7145219 1982
94
[Uremic neuropathy: clinical evolution and therapeutic results in a 5-year period of observation]. 61
7049810 1982
95
Progress of peripheral uremic neuropathy during continuous ambulatory peritoneal dialysis (CAPD). 61
6298985 1982
96
Uremic neuropathy: correlations between electroneurographic parameters and serum levels of parathyroid hormone and aluminum. 61
6293832 1982
97
[Studies on uremic neuropathy: with reference to uremic toxin (author's transl)]. 61
6276436 1981
98
Biochemistry of renal failure. 61
7023344 1981
99
Blood levels of middle molecules and their effects on motor nerve conduction velocity. 61
7295082 1981
100
Peripheral neuropathy in uremic patients and in renal transplant recipients. 61
6263034 1981
101
Erythrocyte transketolase activity in uremia. 61
6256098 1980
102
Tibial nerve H-reflex and F-wave studies in patients with uremic neuropathy. 61
6252459 1980
103
Detection of uremic neuropathy by reflex response latency. 61
6251176 1980
104
Peripheral neuropathies associated with chronic renal failure. 61
6250697 1980
105
[Electrophysiological aspects of uremic neuropathy. I: electromyography, neural motor and sensory conduction and reflex responses]. 61
7394221 1980
106
[Electrophysiological aspects of uremic neuropathy. II. effects of ischemia on the evoked sensory potential]. 61
7394222 1980
107
Malrecognition of taste in uremia. 61
7393376 1980
108
Motor nerve conduction indicators in uremic neuropathy. 61
7356822 1980
109
H-reflex latency in uremic neuropathy: correlation with NCV and clinical findings. 61
224838 1979
110
[Clinical and electromyographic data for the identification and classification of uremic neuropathy; a method for data standardization]. 61
553293 1979
111
Screening for peripheral neuropathy in patients treated by chronic hemodialysis. 61
233738 1978
112
[Determination of "middle molecules" presenting vitamin B12 molecular size in normal and uremic body fluids (author's transl)]. 61
670358 1978
113
[Uremic neuropathy]. 61
211298 1978
114
Search for the uremic toxin. Decreased motor-nerve conduction velocity and elevated parathyroid hormone in uremia. 61
205786 1978
115
Uremic neuropathy: evidence of middle molecule toxicity. 61
687020 1978
116
[Neural conduction velocity in uremic neuropathy]. 61
231817 1978
117
[Effects of short-term dialysis with broad-surface capillary kidneys on the peripheral uremic neuropathy]. 61
741932 1978
118
Tissue culture studies of possible uremic neurotoxins: myoinositol. 61
562436 1977
119
[Uremic neuropathy. Study of the motor conduction rate in patients treated with maintenance hemodialysis and peritoneal dialysis]. 61
193173 1977
120
Short dialysis, middle molecules, and uremia. 61
835933 1977
121
Letter: Carbamazepine in uremic neuropathy. 61
176912 1976
122
Electrophysiologic changes in uremic neuropathy after successful renal transplantation. 61
176611 1976
123
[Study of nerve conduction velocity in uremic neuropathy]. 61
1052935 1976
124
Uremic neuropathy. III. Controlled study of restricted protein and fluid diet and infrequent hemodialysis versus conventional hemodialysis treatment. 61
171524 1975
125
[Electrophysiological examination of uremic neuropathy (author's transl)]. 61
1157060 1975
126
Preservation of peripheral nerve function in severe uremia during treatment with low protein high calorie diet and surplus of essential amino acids. 61
1114881 1975
127
[Uremic neuropathy. A clinical electrophysiological correlation (author's transl)]. 61
4850062 1974
128
Uremic neuropathy. Monitoring of transketolase activity inhibition in a child. 61
4265477 1973
129
[Uremic neuropathy in relation duration of dialysis and dialyzer]. 61
4339543 1972
130
Relationship of nervous tissue transketolase to the neuropathy in chronic uremia. 61
5096513 1971
131
Uremic neuropathy. 61
4328348 1971
132
[Ultrastructure of the sural nerve in the convalescent stage of acute uremic neuropathy due to sodium bromate intoxication]. 61
4338750 1971
133
Segmental demyelination secondary to axonal degeneration in uremic neuropathy. 61
4326086 1971
134
Effects of renal transplantation on uremic neuropathy. A clinical and electrophysiologic study. 61
4324615 1971
135
Recovery from uremic neuropathy. 61
4324616 1971
136
[Uremic neuropathy]. 61
4331073 1971
137
Effect of hemodialysis on the inhibition of nervous tissue transketolase and on uremic neuropathy. 61
5158138 1971
138
Transketolase inhibition as a mechanism in uremic neuropathy. 61
5164301 1971
139
Observations on plasma magnesium levels in patients with uremic neuropathy under treatment by periodic hemodialysis. 61
5466463 1970
140
[Latent uremic neuropathy. Electromyographic and electroencephalographic observations in chronic renal patients treated with conservative therapy and with peritoneal dialysis]. 61
5760426 1968
141
Uremic neuropathy. 61
4378313 1967
142
Restless legs syndrome in uremic neuropathy. 61
4286316 1966

Variations for Uremic Neuropathy

Expression for Uremic Neuropathy

Search GEO for disease gene expression data for Uremic Neuropathy.

Pathways for Uremic Neuropathy

GO Terms for Uremic Neuropathy

Biological processes related to Uremic Neuropathy according to GeneCards Suite gene sharing:

(showing 2, show less)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of neuron projection development GO:0010977 8.96 PMP22 B2M
2 response to cadmium ion GO:0046686 8.62 PTH B2M

Sources for Uremic Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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