Ureter Squamous Cell Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Ureter Squamous Cell Carcinoma

MalaCards integrated aliases for Ureter Squamous Cell Carcinoma:

Name: Ureter Squamous Cell Carcinoma ¹¹ ¹⁴ ⁷¹

Ureteral Epidermoid Carcinoma ¹¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Skin diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:5539

NCIt ⁴⁹ C6154

UMLS ⁷¹ C1336879

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Summaries for Ureter Squamous Cell Carcinoma

Disease Ontology: ¹¹ A squamous cell carcinoma that is located in the ureter.

MalaCards based summary: Ureter Squamous Cell Carcinoma, also known as ureteral epidermoid carcinoma, is related to adenofibroma and serous cystadenocarcinoma, and has symptoms including flank pain An important gene associated with Ureter Squamous Cell Carcinoma is CDKN2B-AS1 (CDKN2B Antisense RNA 1). The drugs Nivolumab and Ipilimumab have been mentioned in the context of this disorder. Affiliated tissues include ureter.

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Related Diseases for Ureter Squamous Cell Carcinoma

Diseases related to Ureter Squamous Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 286)

#	Related Disease	Score	Top Affiliating Genes
1	adenofibroma	10.2	NAPSA KRT7
2	serous cystadenocarcinoma	10.2	NAPSA KRT7
3	cervical mucinous adenocarcinoma	10.2	NAPSA KRT7
4	cervical clear cell adenocarcinoma	10.2	NAPSA KRT7
5	ovarian endodermal sinus tumor	10.1	NAPSA KRT7
6	ovarian primitive germ cell tumor	10.1	NAPSA KRT7
7	bladder clear cell adenocarcinoma	10.1	NAPSA KRT7
8	laryngeal adenoid cystic carcinoma	10.1	KRT7 KRT5
9	ceruminoma	10.1	KRT7 KRT5
10	seminal vesicle adenocarcinoma	10.1	KRT7 KLK3
11	subareolar duct papillomatosis	10.1	KRT7 KRT5
12	nipple benign neoplasm	10.1	KRT7 KRT5
13	vulvar sebaceous carcinoma	10.1	KRT7 KRT5
14	rete testis neoplasm	10.1	KRT7 KRT5
15	urethra cancer	10.1	KRT7 KLK3
16	adenosquamous gallbladder carcinoma	10.1	KRT7 KRT5
17	endometrial squamous cell carcinoma	10.1	KRT7 KRT5
18	rectum squamous cell carcinoma	10.1	KRT7 KRT5
19	middle ear adenoma	10.1	KRT7 KRT5
20	rete testis adenocarcinoma	10.1	KRT7 KRT5
21	necrotizing sialometaplasia	10.1	KRT7 KRT5
22	auditory system benign neoplasm	10.1	KRT7 KRT5
23	breast mucoepidermoid carcinoma	10.1	KRT7 KRT5
24	papillary squamous carcinoma	10.1	KRT7 KRT5
25	benign breast adenomyoepithelioma	10.1	KRT7 KRT5
26	breast adenomyoepithelioma	10.1	KRT7 KRT5
27	ceruminous adenocarcinoma	10.1	KRT7 KRT5
28	breast papillary carcinoma	10.1	KRT7 KRT5
29	cystitis cystica	10.1	KRT7 KLK3
30	mixed epithelial stromal tumour	10.1	KRT7 KLK3
31	breast myoepithelial neoplasm	10.1	KRT7 KRT5
32	gastric squamous cell carcinoma	10.1	KRT7 KRT5
33	sublingual gland cancer	10.1	KRT7 KRT5
34	breast metaplastic carcinoma	10.1	KRT7 KRT5
35	metatypical basal cell carcinoma	10.1	KRT7 KRT5
36	balloon cell malignant melanoma	10.1	KRT7 KRT5
37	sensory organ benign neoplasm	10.1	KRT7 KRT5
38	breast secretory carcinoma	10.1	KRT7 KRT5
39	breast adenoid cystic carcinoma	10.1	KRT7 KRT5
40	sinonasal undifferentiated carcinoma	10.1	KRT7 KRT5
41	esophageal neuroendocrine tumor	10.1	NAPSA KRT5
42	breast leiomyosarcoma	10.1	KRT7 KRT5
43	prostatic adenoma	10.1	KLK3 CDKN2B-AS1
44	middle ear adenocarcinoma	10.1	KRT7 KRT5
45	penile urethral cancer	10.1	KRT5 KLK3
46	epithelial-myoepithelial carcinoma	10.1	KRT7 KRT5
47	myoepithelial carcinoma	10.1	KRT7 KRT5
48	thymus large cell carcinoma	10.1	KRT7 KRT5
49	prostate neuroendocrine neoplasm	10.1	KRT7 KLK3
50	cribriform carcinoma	10.1	KRT7 KRT5

Graphical network of the top 20 diseases related to Ureter Squamous Cell Carcinoma:

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Symptoms & Phenotypes for Ureter Squamous Cell Carcinoma

UMLS symptoms related to Ureter Squamous Cell Carcinoma:

flank pain

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Drugs & Therapeutics for Ureter Squamous Cell Carcinoma

Drugs for Ureter Squamous Cell Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Nivolumab

Approved

Phase 2

946414-94-4

2

Ipilimumab

Approved

Phase 2

477202-00-9

3

Immunoglobulins

Phase 2

4

Immune Checkpoint Inhibitors

Phase 2

5

Antibodies, Monoclonal

Phase 2

6

Antibodies

Phase 2

7

Antineoplastic Agents, Immunological

Phase 2

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	DART: Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors	Recruiting	NCT02834013	Phase 2

Search NIH Clinical Center for Ureter Squamous Cell Carcinoma

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Genetic Tests for Ureter Squamous Cell Carcinoma

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Anatomical Context for Ureter Squamous Cell Carcinoma

Organs/tissues related to Ureter Squamous Cell Carcinoma:

FMA: Ureter

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Publications for Ureter Squamous Cell Carcinoma

Articles related to Ureter Squamous Cell Carcinoma:

#	Title	Authors	PMID	Year
1	Primary renal pelvis and ureter squamous cell carcinoma (SCC): a rare case report and review of literature. ⁶²	Salehipour M...Tayebi S	31303798	2019
2	[Primary squamous cell carcinoma of the ureter: a case report]. ⁶²	Yasui T...Kohri K	7645455	1995
3	An inherited form of large bowel cancer: Muir's syndrome. ⁶²	Anderson DE	7357506	1980

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Genes for Ureter Squamous Cell Carcinoma

Genes related to Ureter Squamous Cell Carcinoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	CDKN2B-AS1	CDKN2B Antisense RNA 1	RNA Gene	5.38	DISEASES inferred ¹⁴
2	NAPSA	Napsin A Aspartic Peptidase	Protein Coding	4.37	DISEASES inferred ¹⁴
3	KRT7	Keratin 7	Protein Coding	4.24	DISEASES inferred ¹⁴
4	KRT5	Keratin 5	Protein Coding	3.63	DISEASES inferred ¹⁴
5	GATA3	GATA Binding Protein 3	Protein Coding	3.41	DISEASES inferred ¹⁴
6	CEACAM5	CEA Cell Adhesion Molecule 5	Protein Coding	2.96	DISEASES inferred ¹⁴
7	KLK3	Kallikrein Related Peptidase 3	Protein Coding	2.82	DISEASES inferred ¹⁴

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Variations for Ureter Squamous Cell Carcinoma

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Expression for Ureter Squamous Cell Carcinoma

Search GEO for disease gene expression data for Ureter Squamous Cell Carcinoma.

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Pathways for Ureter Squamous Cell Carcinoma

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GO Terms for Ureter Squamous Cell Carcinoma

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Sources for Ureter Squamous Cell Carcinoma

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: URT021 MIFTS: 21	Ureter Squamous Cell Carcinoma Categories: Cancer diseases, Skin diseases	Data Licensing For inquiries, contact: [email protected]
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