MCID: URT031
MIFTS: 42

Ureteral Disease

Categories: Nephrological diseases

Aliases & Classifications for Ureteral Disease

MalaCards integrated aliases for Ureteral Disease:

Name: Ureteral Disease 12 15
Ureteral Diseases 44 72
Ureteral Disorders 43
Disorder of Ureter 72

Classifications:



External Ids:

Disease Ontology 12 DOID:1426
MeSH 44 D014515
NCIt 50 C27148
UMLS 72 C0041954 C0403608

Summaries for Ureteral Disease

MedlinePlus : 43 Your kidneys make urine by filtering wastes and extra water from your blood. The urine travels from the kidneys to the bladder in two thin tubes called ureters. The ureters are about 8 to 10 inches long. Muscles in the ureter walls tighten and relax to force urine down and away from the kidneys. Small amounts of urine flow from the ureters into the bladder about every 10 to 15 seconds. Sometimes the ureters can become blocked or injured. This can block the flow of urine to the bladder. If urine stands still or backs up the ureter, you may get a urinary tract infections. Doctors diagnose problems with the ureters using different tests. These include urine tests, x-rays, and examination of the ureter with a scope called a cystoscope. Treatment depends on the cause of the problem. It may include medicines and, in severe cases, surgery. NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary : Ureteral Disease, also known as ureteral diseases, is related to vesicoureteral reflux 1 and ureterocele. An important gene associated with Ureteral Disease is SLC3A1 (Solute Carrier Family 3 Member 1), and among its related pathways/superpathways are Pathways in cancer and Mesodermal Commitment Pathway. The drugs Tamsulosin and Adrenergic alpha-1 Receptor Antagonists have been mentioned in the context of this disorder. Affiliated tissues include kidney, testes and smooth muscle, and related phenotypes are cardiovascular system and homeostasis/metabolism

Disease Ontology : 12 A urinary system disease that is located in the ureter.

Wikipedia : 75 In human anatomy, the ureters are tubes made of smooth muscle fibers that propel urine from the kidneys... more...

Related Diseases for Ureteral Disease

Diseases related to Ureteral Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
# Related Disease Score Top Affiliating Genes
1 vesicoureteral reflux 1 30.8 UPK3A ROBO2 REN PAX2 MCU
2 ureterocele 11.5
3 hypertrophic scars 10.4 TGFB1 SMAD3 SMAD2
4 peyronie's disease 10.3 TGFB1 SMAD7 SMAD3
5 hypochondrogenesis 10.3 SMAD7 SMAD3 SMAD2
6 spastic paraplegia 3, autosomal dominant 10.3 TGFB1 SMAD2 CDH1
7 familial vesicoureteral reflux 10.2 TGFB1 ROBO2
8 multicystic dysplastic kidney 10.2 REN PAX2
9 clear cell adenocarcinoma 10.2 SMAD3 SMAD2 PAX2
10 obstructive nephropathy 10.2 TGFB1 SMAD3 SMAD2 REN
11 inappropriate adh syndrome 10.2 REN AQP2
12 pauci-immune glomerulonephritis 10.1 SMAD2 CCN2 BMP7
13 ureteral obstruction 10.1 TGFB1 BMP7 AQP2
14 bladder disease 10.1 UPK3A SLC7A9 SLC3A1 CDH1
15 spondylocarpotarsal synostosis syndrome 10.1 SMAD3 SMAD2 CCN2
16 pulmonary fibrosis 9.9 TGFB1 SMAD7 SMAD3 CCN2
17 cystinuria 9.9 SLC7A9 SLC3A2 SLC3A1 PREPL
18 urinary system disease 9.9 TGFB1 REN CCN2 AQP2
19 hydronephrosis 9.8
20 stiff skin syndrome 9.8 TGFB1 CCN2
21 nephrogenic systemic fibrosis 9.8 TGFB1 SMAD7 SMAD3 SMAD2 CCN2
22 liver cirrhosis 9.8 TGFB1 REN CCN2 AQP2
23 pulmonary fibrosis, idiopathic 9.7 TGFB1 SMAD3 SMAD2 CDH1 CCN2
24 hypotonia-cystinuria syndrome 9.7 SLC7A9 SLC3A1 PREPL PPM1B
25 renal tuberculosis 9.7
26 renal hypodysplasia/aplasia 1 9.7
27 wilms tumor 5 9.7
28 renal hypertension 9.7
29 pyelonephritis 9.7
30 renovascular hypertension 9.7
31 transitional cell carcinoma 9.7
32 glomerulonephritis 9.7
33 kidney disease 9.3 TGFB1 REN PAX2 CCN2 BMP7 AQP2
34 urinary tract obstruction 9.1 TGFB1 SMAD7 SMAD3 SMAD2 REN CDH1
35 renal fibrosis 9.0 TGFB1 SMAD7 SMAD3 SMAD2 REN CDH1

Graphical network of the top 20 diseases related to Ureteral Disease:



Diseases related to Ureteral Disease

Symptoms & Phenotypes for Ureteral Disease

MGI Mouse Phenotypes related to Ureteral Disease:

46 (show all 16)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.33 BMP7 CCN2 CDH1 FN1 MCU PAX2
2 homeostasis/metabolism MP:0005376 10.33 AQP2 CCN2 CDH1 FN1 MCU REN
3 growth/size/body region MP:0005378 10.32 AQP2 BMP7 CCN2 CDH1 FN1 MCU
4 cellular MP:0005384 10.28 CCN2 CDH1 FN1 MCU PAX2 ROBO2
5 mortality/aging MP:0010768 10.27 AQP2 BMP7 CCN2 CDH1 FN1 MCU
6 behavior/neurological MP:0005386 10.26 AQP2 BMP7 MCU PREPL REN ROBO2
7 embryo MP:0005380 10.19 BMP7 CCN2 CDH1 FN1 PAX2 PPM1B
8 immune system MP:0005387 10.17 BMP7 CDH1 FN1 REN SLC3A1 SLC3A2
9 digestive/alimentary MP:0005381 10.16 BMP7 CCN2 CDH1 ROBO2 SLC3A2 SMAD2
10 craniofacial MP:0005382 10.07 BMP7 CCN2 FN1 SMAD2 SMAD3 SMAD7
11 integument MP:0010771 10.06 AQP2 BMP7 CCN2 CDH1 FN1 SMAD2
12 muscle MP:0005369 9.92 FN1 MCU PREPL REN ROBO2 SLC3A1
13 normal MP:0002873 9.76 BMP7 CCN2 CDH1 FN1 REN ROBO2
14 neoplasm MP:0002006 9.73 CDH1 FN1 SLC3A2 SMAD2 SMAD3 TGFB1
15 renal/urinary system MP:0005367 9.65 AQP2 BMP7 PAX2 REN ROBO2 SLC3A1
16 reproductive system MP:0005389 9.36 AQP2 BMP7 CDH1 FN1 PAX2 REN

Drugs & Therapeutics for Ureteral Disease

Drugs for Ureteral Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 22)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tamsulosin Approved, Investigational Phase 4 106133-20-4 129211
2 Adrenergic alpha-1 Receptor Antagonists Phase 4
3 Adrenergic alpha-Antagonists Phase 4
4 Adrenergic Antagonists Phase 4
5 Adrenergic Agents Phase 4
6 Neurotransmitter Agents Phase 4
7
Lidocaine Approved, Vet_approved Phase 2 137-58-6 3676
8 Anesthetics, Local Phase 2
9 Sodium Channel Blockers Phase 2
10 Diuretics, Potassium Sparing Phase 2
11 Peripheral Nervous System Agents Phase 2
12 Anesthetics Phase 2
13 Central Nervous System Depressants Phase 2
14 Anti-Arrhythmia Agents Phase 2
15
Gemcitabine Approved Phase 1 95058-81-4 60750
16
Cisplatin Approved Phase 1 15663-27-1 84093 441203 2767
17 Anti-Infective Agents Phase 1
18 Immunosuppressive Agents Phase 1
19 Antiviral Agents Phase 1
20 Antimetabolites, Antineoplastic Phase 1
21 Antimetabolites Phase 1
22 Immunologic Factors Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Effect of Daily Versus Twice Per Day Tamsulosin on Ureteral Stent Symptoms Following Ureteroscopy for Nephrolithiasis Enrolling by invitation NCT03799120 Phase 4 Tamsulosin BID
2 A Randomized Control Trial Comparing Single to Multiple Application Lidocaine Analgesia Prior to Urethral Catheterization Procedures Completed NCT00142064 Phase 2
3 A Phase I/1b Study of Enzalutamide in Combination With Gemcitabine and Cisplatin in Bladder Cancer Completed NCT02300610 Phase 1 Enzalutamide;Cisplatin;Gemcitabine

Search NIH Clinical Center for Ureteral Disease

Cochrane evidence based reviews: ureteral diseases

Genetic Tests for Ureteral Disease

Anatomical Context for Ureteral Disease

MalaCards organs/tissues related to Ureteral Disease:

41
Kidney, Testes, Smooth Muscle, Prostate, Cervix

The Foundational Model of Anatomy Ontology organs/tissues related to Ureteral Disease:

19
Ureter

Publications for Ureteral Disease

Articles related to Ureteral Disease:

(show top 50) (show all 72)
# Title Authors PMID Year
1
Risk Factors for Ureteral Damage in Ureteroscopic stone Treatment: Results of the German Prospective Multicentre Benchmarks of Ureterorenoscopic Stone Treatment-Results in Terms of Complications, Quality of Life, and Stone-Free Rates Project. 17
30481771 2019
2
Tail sign: Phlebolith. 17
30309081 2018
3
Ureteroscopic lithotripsy in the Trendelenburg position for extracting obstructive upper ureteral obstruction stones: a prospective, randomized, comparative trial. 17
30334631 2018
4
In vitro, in vivo, and clinical tests of a novel flexible ureteroscope for the diagnosis and treatment of kidney and ureteral diseases. 38
30182078 2018
5
Interventional Radiology and Interventional Endoscopy in Treatment of Nephroureteral Disease in the Dog and Cat. 38
29909932 2018
6
Therapeutic strategies for upper tract urothelial carcinoma. 38
29848133 2018
7
Feline ureteral obstructions Part 2: surgical management. 38
29781101 2018
8
Numerical analysis of urine flow through the side holes of a double J stent in a ureteral stenosis. 38
28582893 2017
9
Long-Term Outcomes of Laparoscopic Nephroureterectomy with Transurethral Circumferential Excision of the Ureteral Orifice for Urothelial Carcinoma. 38
28385045 2017
10
Analysis of Urine Flow in Three Different Ureter Models. 38
28659992 2017
11
The effect of tumor location on oncologic outcomes in patients with upper urinary tract urothelial carcinoma stratified by pathologic stage. 38
26351152 2016
12
Deep infiltrating endometriosis affecting the urinary tract-surgical treatment and fertility outcomes in 2004-2013. 38
28003801 2016
13
Renal Autotransplantation: 27-Year Experience at 2 Institutions. 38
26055825 2015
14
MULTIDETECTOR-ROW COMPUTED TOMOGRAPHIC CHARACTERISTICS OF PRESUMED PREURETERAL VENA CAVA IN CATS. 38
25786990 2015
15
Oncologic outcomes and prognostic impact of urothelial recurrences in patients undergoing segmental and total ureterectomy for upper tract urothelial carcinoma. 38
26085878 2015
16
Robotic-assisted laparoscopic surgery: recent advances in urology. 38
24993800 2014
17
Effects of furosemide on ureteral diameter and attenuation using computed tomographic excretory urography in normal dogs. 38
22963173 2013
18
Role of routine transurethral biopsy and isolated upper tract cytology after intravesical treatment of high-grade non-muscle invasive bladder cancer. 38
22762480 2012
19
Practical value of intravenous urography combined with add-on CT in diagnosing ureteral abnormalities. 38
22613603 2012
20
Bilateral hydronephrosis secondary to endometriosis managed by endoscopic ureteral stent placement in a captive Guinea baboon (Papio papio). 38
22204076 2011
21
Incidence and survival of patients with carcinoma of the ureter and renal pelvis in the USA, 1973-2005. 38
20825397 2011
22
Wegener's granulomatosis: a rare cause of hydronephrosis. 38
21577265 2011
23
Laparoscopic conservative management of ureteral endometriosis. 38
20610998 2010
24
Laparoscopic management of ureteral endometriosis: the Stanford University hospital experience with 96 consecutive cases. 38
19837436 2009
25
Techniques for laparoscopic and robotic localization of intraluminal ureteral pathology. 38
19147208 2009
26
Arteriovenous fistula in an autotransplanted kidney segment: successful angiographic management. 38
19921990 2009
27
[Bilateral multiple ureteral polyps causing intermittent hydronephrosis: a case report]. 38
18260348 2008
28
Reno-ureteral diseases inducing hypertension in children. 38
19480305 2008
29
Ureteral intussusception due to a polyp. 38
17151895 2007
30
[Holmium: YAG laser lithotripsy under ureteroscopy for treating urinary caluli combined with acute renal failure]. 38
16568567 2006
31
[Radical operative treatment (nephrectomy and nephroureterectomy) in urology. Aspects and opinions]. 38
16042068 2004
32
Evaluation of the ureter and ureterovesicular junction using helical computed tomographic excretory urography in healthy dogs. 38
12718349 2003
33
Endometriosis of the urinary tract. 38
12476526 2002
34
[Spiral CT urography and CT virtual endoscopy in detecting urological diseases]. 38
12133345 2002
35
[Technical solution for single kidney patients with multiple ureteral neoplasms]. 38
11822068 2001
36
In vitro contractile effects of neurokinin receptor blockade in the human ureter. 38
11547127 2001
37
A new generation of semirigid fiberoptic ureteroscopes. 38
10102126 1999
38
Upper ureteral reconstructive surgery. 38
10086059 1999
39
Demonstration of a "renogastric reflex" after rapid distension of renal pelvis and ureter in nonanesthetized patients. 38
9886585 1999
40
A study of the effect of renal pelvic and ureteric distention on the anorectal function with identification of the "reno-anal reflex". 38
9563975 1998
41
Ipsilateral ureteroureterostomy for single ureteral reflux or obstruction in a duplicate system. 38
9474221 1998
42
Subcutaneous ureteral replacement: a canine model. 38
9659639 1998
43
Use of small and large bowel in renal transplantation. 38
9391535 1997
44
[Long-term follow up of patients surgically treated for pyelo-ureteral disease by the Anderson-Hynes technique]. 38
9181916 1997
45
[Damage to the lumbosacral plexus in psoas hitch operation]. 38
8851298 1996
46
Transurethral ureteroscopic ureterotomy assisted by a prior balloon dilation for relieving ureteral strictures. 38
7714955 1995
47
Extensive dilation of distal ureter for endoscopic treatment of large volume ureteral disease. 38
7869503 1995
48
Efficacy of nonsteroidal anti-inflammatory drugs in the treatment of acute renal colic. A meta-analysis. 38
8002690 1994
49
Percutaneous internal ureteral stent placement: review of technical issues and solutions in 50 consecutive cases. 38
8162683 1994
50
[Spontaneous rupture of the ureter with urinothorax: a case report]. 38
1315194 1992

Variations for Ureteral Disease

Expression for Ureteral Disease

Search GEO for disease gene expression data for Ureteral Disease.

Pathways for Ureteral Disease

Pathways related to Ureteral Disease according to GeneCards Suite gene sharing:

(show all 34)
# Super pathways Score Top Affiliating Genes
1 12.76 TGFB1 SMAD3 SMAD2 FN1 CDH1
2
Show member pathways
12.44 TGFB1 SMAD3 SMAD2 BMP7
3
Show member pathways
12.4 TGFB1 SMAD3 SMAD2 BMP7
4 12.28 TGFB1 SMAD3 SMAD2 CDH1
5
Show member pathways
12.22 TGFB1 SMAD7 SMAD3 SMAD2
6
Show member pathways
12.16 TGFB1 SLC7A9 SLC3A2 FN1
7 12.1 TGFB1 SMAD3 SMAD2 CDH1
8 12.08 TGFB1 SMAD3 SMAD2 MCU
9 12 SMAD3 SMAD2 CDH1 CCN2
10 11.99 TGFB1 SMAD3 SMAD2 PAX2 CCN2 BMP7
11 11.98 TGFB1 SMAD3 SMAD2 BMP7
12 11.93 TGFB1 SMAD7 SMAD3 SMAD2 FN1
13
Show member pathways
11.93 TGFB1 SMAD7 SMAD3 SMAD2 CDH1 CCN2
14 11.86 TGFB1 SMAD3 FN1
15 11.83 TGFB1 SMAD3 SMAD2 FN1
16
Show member pathways
11.79 TGFB1 SMAD3 SMAD2
17 11.79 TGFB1 SMAD7 SMAD3 SMAD2
18 11.7 SMAD7 SMAD3 SMAD2
19
Show member pathways
11.69 TGFB1 SMAD3 SMAD2
20 11.69 TGFB1 SMAD7 SMAD3 SMAD2 BMP7
21 11.69 TGFB1 SMAD7 SMAD3 SMAD2 CDH1 CCN2
22 11.65 TGFB1 SMAD7 SMAD3 SMAD2
23 11.64 SMAD3 SMAD2 CDH1
24 11.63 TGFB1 SMAD3 SMAD2 BMP7
25
Show member pathways
11.62 TGFB1 SMAD7 SMAD3 SMAD2
26 11.56 TGFB1 SMAD7 CCN2 BMP7
27 11.5 TGFB1 SMAD7 SMAD3 SMAD2
28 11.26 TGFB1 SMAD7 SMAD3 SMAD2 CCN2
29
Show member pathways
11.25 SLC7A9 SLC3A2 SLC3A1
30 11.2 TGFB1 SMAD3 SMAD2
31 11.11 SMAD3 SMAD2 CCN2
32 10.95 TGFB1 FN1 CDH1 CCN2 BMP7
33 10.94 SMAD3 SMAD2
34 10.28 TGFB1 SMAD3 SMAD2 FN1 CDH1

GO Terms for Ureteral Disease

Cellular components related to Ureteral Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 apical plasma membrane GO:0016324 9.35 UPK3A SLC7A9 SLC3A2 FN1 AQP2
2 SMAD protein complex GO:0071141 9.16 SMAD3 SMAD2
3 heteromeric SMAD protein complex GO:0071144 8.62 SMAD3 SMAD2
4 plasma membrane GO:0005886 10.03 TGFB1 SMAD7 SMAD3 SLC7A9 SLC3A2 SLC3A1

Biological processes related to Ureteral Disease according to GeneCards Suite gene sharing:

(show all 48)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.95 TGFB1 SMAD3 SMAD2 FN1 CCN2 BMP7
2 leukocyte migration GO:0050900 9.94 TGFB1 SLC7A9 SLC3A2 FN1
3 response to estradiol GO:0032355 9.87 TGFB1 CCN2 BMP7
4 response to organic substance GO:0010033 9.86 TGFB1 REN CDH1
5 response to wounding GO:0009611 9.84 TGFB1 FN1 CCN2
6 response to glucose GO:0009749 9.84 TGFB1 SMAD2 CCN2
7 cellular response to transforming growth factor beta stimulus GO:0071560 9.82 TGFB1 SMAD7 SMAD3
8 regulation of MAPK cascade GO:0043408 9.81 TGFB1 REN BMP7
9 transforming growth factor beta receptor signaling pathway GO:0007179 9.81 TGFB1 SMAD7 SMAD3 SMAD2
10 wound healing GO:0042060 9.8 TGFB1 SMAD3 SMAD2 FN1
11 amino acid transport GO:0006865 9.79 SLC7A9 SLC3A2 SLC3A1
12 positive regulation of bone mineralization GO:0030501 9.76 TGFB1 SMAD3 BMP7
13 positive regulation of protein import into nucleus GO:0042307 9.75 TGFB1 SMAD3 CDH1
14 mesoderm formation GO:0001707 9.74 SMAD3 SMAD2 BMP7
15 kidney development GO:0001822 9.73 UPK3A REN BMP7
16 negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 9.73 TGFB1 SMAD7 SMAD3 SMAD2
17 endoderm development GO:0007492 9.72 TGFB1 SMAD3 SMAD2
18 water transport GO:0006833 9.7 UPK3A AQP2
19 positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 9.7 TGFB1 PAX2
20 activin receptor signaling pathway GO:0032924 9.7 SMAD3 SMAD2
21 negative regulation of cell-cell adhesion GO:0022408 9.69 TGFB1 CDH1
22 pathway-restricted SMAD protein phosphorylation GO:0060389 9.68 TGFB1 SMAD7
23 lens fiber cell differentiation GO:0070306 9.68 TGFB1 SMAD3
24 salivary gland morphogenesis GO:0007435 9.68 TGFB1 BMP7
25 response to cholesterol GO:0070723 9.68 TGFB1 SMAD2
26 primary miRNA processing GO:0031053 9.67 SMAD3 SMAD2
27 nodal signaling pathway GO:0038092 9.67 SMAD3 SMAD2
28 SMAD protein signal transduction GO:0060395 9.67 TGFB1 SMAD3 SMAD2 BMP7
29 pericardium development GO:0060039 9.66 SMAD3 SMAD2
30 embryonic foregut morphogenesis GO:0048617 9.65 SMAD3 SMAD2
31 response to laminar fluid shear stress GO:0034616 9.65 TGFB1 SMAD7
32 metanephric collecting duct development GO:0072205 9.64 PAX2 AQP2
33 endocardial cushion formation GO:0003272 9.63 ROBO2 BMP7
34 embryonic pattern specification GO:0009880 9.63 SMAD3 SMAD2 BMP7
35 common-partner SMAD protein phosphorylation GO:0007182 9.62 TGFB1 SMAD2
36 positive regulation of epithelial to mesenchymal transition GO:0010718 9.62 TGFB1 SMAD3 SMAD2 BMP7
37 positive regulation of extracellular matrix assembly GO:1901203 9.61 TGFB1 SMAD3
38 regulation of striated muscle tissue development GO:0016202 9.6 TGFB1 SMAD3
39 L-cystine transport GO:0015811 9.59 SLC7A9 SLC3A1
40 mesonephros development GO:0001823 9.58 REN PAX2 BMP7
41 paraxial mesoderm morphogenesis GO:0048340 9.54 SMAD3 SMAD2
42 evasion or tolerance of host defenses by virus GO:0019049 9.52 TGFB1 SMAD3
43 SMAD protein complex assembly GO:0007183 9.43 TGFB1 SMAD3 SMAD2
44 L-alpha-amino acid transmembrane transport GO:1902475 9.39 SLC7A9
45 regulation of binding GO:0051098 9.33 TGFB1 SMAD3 SMAD2
46 regulation of transforming growth factor beta receptor signaling pathway GO:0017015 9.26 TGFB1 SMAD7 SMAD3 SMAD2
47 ureteric bud development GO:0001657 9.1 TGFB1 SMAD7 SMAD3 SMAD2 ROBO2 BMP7
48 positive regulation of transcription, DNA-templated GO:0045893 10.08 TGFB1 SMAD3 SMAD2 PAX2 CDH1 BMP7

Molecular functions related to Ureteral Disease according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.93 UPK3A TGFB1 SMAD7 SMAD3 SMAD2 SLC7A9
2 beta-catenin binding GO:0008013 9.65 SMAD7 SMAD3 CDH1
3 collagen binding GO:0005518 9.61 SMAD7 SMAD3 FN1
4 enhancer binding GO:0035326 9.52 SMAD3 SMAD2
5 neutral amino acid transmembrane transporter activity GO:0015175 9.51 SLC7A9 SLC3A2
6 co-SMAD binding GO:0070410 9.49 SMAD3 SMAD2
7 I-SMAD binding GO:0070411 9.46 SMAD7 SMAD2
8 primary miRNA binding GO:0070878 9.4 SMAD3 SMAD2
9 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity GO:0030618 9.37 SMAD3 SMAD2
10 type I transforming growth factor beta receptor binding GO:0034713 9.33 TGFB1 SMAD7 SMAD2
11 amino acid transmembrane transporter activity GO:0015171 9.32 SLC7A9 SLC3A1
12 L-cystine transmembrane transporter activity GO:0015184 9.26 SLC7A9 SLC3A1
13 transforming growth factor beta receptor binding GO:0005160 8.92 TGFB1 SMAD3 SMAD2 BMP7

Sources for Ureteral Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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