Aliases & Classifications for Ureterocele

MalaCards integrated aliases for Ureterocele:

Name: Ureterocele 56 12 43 15 17

Characteristics:

OMIM:

56
Inheritance:
autosomal dominant


HPO:

31
ureterocele:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

Disease Ontology 12 DOID:4022
OMIM 56 191650
MeSH 43 D014518
NCIt 49 C123159
SNOMED-CT 67 12818004
MedGen 41 C0041960
SNOMED-CT via HPO 68 263681008
UMLS 71 C0041960

Summaries for Ureterocele

Disease Ontology : 12 A ureteral disease that is characterized as a congenital anomaly in which the distal end of the ureter swells as it enters the bladder.

MalaCards based summary : Ureterocele is related to vesicoureteral reflux 1 and urethral diverticulum. An important gene associated with Ureterocele is MCU (Mitochondrial Calcium Uniporter), and among its related pathways/superpathways are SALM protein interactions at the synapses and ID signaling pathway. Affiliated tissues include kidney, prostate and testis, and related phenotypes are ureterocele and duplicated collecting system

Wikipedia : 74 A ureterocele is a congenital abnormality found in the ureter. In this condition the distal ureter... more...

More information from OMIM: 191650

Related Diseases for Ureterocele

Diseases related to Ureterocele via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 100)
# Related Disease Score Top Affiliating Genes
1 vesicoureteral reflux 1 31.1 ZCCHC14 PRUNE1 PAX2 MCU
2 urethral diverticulum 30.3 PAX8 MCU
3 renal hypodysplasia/aplasia 1 29.9 PAX8 PAX2 LHX1
4 skin creases, congenital symmetric circumferential, 1 11.3
5 hydronephrosis 10.8
6 acute cystitis 10.8
7 renal dysplasia 10.5
8 urinary tract obstruction 10.5
9 pyelonephritis 10.5
10 bladder neck obstruction 10.3
11 bladder diverticulum 10.3
12 transitional cell carcinoma 10.3
13 ureteral obstruction 10.3
14 horseshoe kidney 10.3
15 kidney disease 10.2
16 multicystic dysplastic kidney 10.2
17 bacteriuria 10.2
18 cystitis 10.2
19 prostatic hyperplasia, benign 10.1
20 polycystic kidney disease 10.1
21 interstitial nephritis 10.1
22 chronic pyelonephritis 10.1
23 prostatic hypertrophy 10.1
24 bladder calculus 10.1
25 oligohydramnios 10.1
26 ureterolithiasis 10.1
27 prostatic adenoma 10.1
28 acute pyelonephritis 10.1
29 urethral calculus 10.1
30 47,xyy 10.1
31 posterior urethral valves 10.1
32 back pain 10.1
33 urethra adenocarcinoma 10.0 PAX8 PAX2
34 nephrogenic adenoma of urinary bladder 10.0 PAX8 PAX2
35 nephrogenic adenoma 10.0 PAX8 PAX2
36 mayer-rokitansky-kuster-hauser syndrome 10.0 PAX2 LHX1
37 rete testis adenoma 10.0 PAX8 PAX2
38 wolffian duct adenoma 10.0 PAX8 PAX2
39 urethra cancer 10.0 PAX8 PAX2
40 nephrogenic adenoma of the urethra 10.0 PAX8 PAX2
41 hyperuricemic nephropathy, familial juvenile, 1 10.0 PAX2 NPHP1
42 urethral benign neoplasm 10.0 PAX8 PAX2
43 renal adenoma 10.0 PAX8 PAX2
44 epididymis adenocarcinoma 10.0 PAX8 PAX2
45 epididymis cancer 10.0 PAX8 PAX2
46 endosalpingiosis 10.0 PAX8 PAX2
47 nasal cavity olfactory neuroblastoma 10.0 PAX8 PAX2
48 fallopian tube endometrioid adenocarcinoma 10.0 PAX8 PAX2
49 prune belly syndrome 9.9 PRUNE1 PAX2
50 bladder clear cell adenocarcinoma 9.9 PAX8 PAX2

Graphical network of the top 20 diseases related to Ureterocele:



Diseases related to Ureterocele

Symptoms & Phenotypes for Ureterocele

Human phenotypes related to Ureterocele:

31
# Description HPO Frequency HPO Source Accession
1 ureterocele 31 HP:0000070
2 duplicated collecting system 31 HP:0000081

Symptoms via clinical synopsis from OMIM:

56
G U:
ureterocele

Radiology:
double urinary collecting systems on intravenous pyelography

Clinical features from OMIM:

191650

MGI Mouse Phenotypes related to Ureterocele:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.76 LHX1 MREG NPHP1 PAX2 PAX8 PCDH9
2 renal/urinary system MP:0005367 9.43 LHX1 NPHP1 PAX2 PAX8 PTPRF PTPRS
3 vision/eye MP:0005391 9.1 MREG NPHP1 PAX2 PAX8 PTPRF PTPRS

Drugs & Therapeutics for Ureterocele

Search Clinical Trials , NIH Clinical Center for Ureterocele

Cochrane evidence based reviews: ureterocele

Genetic Tests for Ureterocele

Anatomical Context for Ureterocele

MalaCards organs/tissues related to Ureterocele:

40
Kidney, Prostate, Testis, Skin, Eye, Thymus, Heart

Publications for Ureterocele

Articles related to Ureterocele:

(show top 50) (show all 1179)
# Title Authors PMID Year
1
Ureteroceles in siblings. 61 56
7411701 1980
2
Ureterocele--a familial congenital anomaly. 61 56
442384 1979
3
Bilateral ureteral ectopia with urinary incontinence in a mother and daughter. 56
6057859 1967
4
Duplicated collecting system with ectopic prostatic implantation: Therapeutic conservative robot assisted approach, about a case report. 61
31908968 2020
5
Classifying seminal vesicle cysts in the diagnosis and treatment of Zinner syndrome: A report of six cases and review of available literature. 61
31729082 2020
6
Antibiotic Prophylaxis Prescribing Patterns of Pediatric Urologists for Children with Vesicoureteral Reflux and other Congenital Anomalies of the Kidney and Urinary Tract. 61
31758980 2020
7
Multicystic dysplastic kidney - treat each case on its merits. 61
31987520 2020
8
Holmium: Yttrium-aluminum-garnet laser for endoscopic decompression of ureterocele in the first months of life: A comparison with electrosurgery. 61
31983823 2020
9
Virtual Three-Dimensional Magnetic Resonance Fetal Cystoscopy: A Novel Modality for Precise in Utero Evaluation of Urinary Tract. 61
30471075 2020
10
Prenatal imaging features and postnatal outcomes of isolated fetal duplex renal collecting system: A systematic review and meta-analysis. 61
31834636 2019
11
Duplicated or Ectopic Renal Collecting System in Two Adult Emergency Department Patients. 61
31810832 2019
12
Advanced small-cell bladder cancer into a ureterocele: A case report and literature review. 61
31440452 2019
13
Transurethral incision as initial option in treatment guidelines for ectopic ureteroceles associated with duplex systems. 61
30603781 2019
14
Cystoscopic transurethral incision in simplex and duplex ureteroceles-is it the definitive procedure? 61
31402102 2019
15
Combined spinal/caudal catheter anesthesia: extending the boundaries of regional anesthesia for complex pediatric urological surgery. 61
31085139 2019
16
Technical challenges of endoscopic treatment for vesicoureteral reflux after Cohen reimplantation. 61
31103394 2019
17
Open vs robotic infant ureteroureterostomy. 61
31151858 2019
18
A novel approach for an old debate in management of ureterocele: long-term outcomes of double-puncture technique. 61
31175023 2019
19
The association of postnatal urinary tract dilation risk score with clinical outcomes. 61
31164273 2019
20
Antenatally detected ureterocele: Associated anomalies and postnatal prognosis. 61
31307746 2019
21
Impact of de novo vesicoureteral reflux on transurethral surgery outcomes in pediatric patients with ureteroceles. 61
31294139 2019
22
Developmental pathology of congenital kidney and urinary tract anomalies. 61
31198539 2019
23
Suprapubic grasper-assisted transvesical endoscopic ureterocele puncture: a novel technical innovation. 61
31080105 2019
24
Laparoscopic transperitoneal heminephrectomy for treatment of the nonfunctioning moiety of duplex kidney in adults: A case series. 61
31098429 2019
25
Ureteral clipping for the treatment of a non-functioning upper kidney moiety associated with a massive ureterocele: step-by-step description of a novel technique. 61
30981638 2019
26
Urologic Complications After Transplantation of Kidneys With Duplicated Ureter: A Retrospective Study. 61
30979464 2019
27
Endoscopic laser-ablation for the treatment of orthotopic and ectopic ureteroceles in dogs: 13 cases (2008-2017). 61
30740771 2019
28
Ipsilateral ureteroureterostomy: does function of the obstructed moiety matter? 61
30243559 2019
29
Tubulocystic anomalies of the mesonephric duct associated with ipsilateral renal dysgenesis. 61
30446299 2019
30
Endoscopic intact removal of medium-size- or multiple bladder stones with the use of transvesical laparoendoscopic single-site surgery. 61
29955919 2019
31
Benefits of spinal anesthesia for urologic surgery in the youngest of patients. 61
30201472 2019
32
Evaluating Outcomes of Differential Surgical Management of Nonfunctioning Upper Pole Renal Moieties in Duplex Collecting Systems. 61
30031832 2019
33
Minimally Invasive Laser Treatment of Ureterocele. 61
31024867 2019
34
Double collecting system with ectopic ureterocele masquerading as an ovarian torsion. 61
30545543 2018
35
The "cyst within cyst" sign of intravesical ureterocele. 61
29687189 2018
36
Robotic surgery in pediatric urology: Current status. 61
30264441 2018
37
Single-system orthotopic ureterocele with calculus masquerading as a bladder tumour - A case report and review of literature. 61
30211009 2018
38
Duplicated Collecting System with Ectopic Vaginal Implantation. 61
30324182 2018
39
Long-term renal outcome in infants with congenital lower urinary tract obstruction. 61
29980359 2018
40
Cobra head sign: Ureterocele. 61
30309064 2018
41
Robotic repair of congenital vesicovaginal fistula masquerading as a ureterocele in a 10-year-old girl. 61
29988812 2018
42
Use of cystoscopic-guided laser ablation for treatment of unilateral ureterovesicular stenosis and secondary orthotopic ureterocele in a female dog. 61
30058967 2018
43
Ureterocele Causing Bladder Outlet Obstruction. 61
29685621 2018
44
Incidence and risk factors for positive urine culture at the time of pediatric urologic surgery. 61
29785658 2018
45
Pelvic dystopia of right rudimentary multicystic dysplastic kidney as a rare cause of bedwetting in a patient with a single pelvic ectopic left kidney, and agenesis of the uterus and vagina (Mayer-Rokitansky-Küster-Hauser syndrome): a case report. 61
29730988 2018
46
Does endoscopic puncture of ureterocele provide not only an initial solution, but also a definitive treatment in all children? Over the 26 years of experience. 61
29594460 2018
47
The half-loop transurethral incision technique for bilateral ureterocele in adult. 61
29785362 2018
48
Prenatal complicated duplex collecting system and ureterocele-Important risk factors for urinary tract infection. 61
28532765 2018
49
Scar acceptance after pediatric urologic surgery. 61
29433993 2018
50
Re: Editorial comment on: Laser-puncture Versus Electrosurgery-incision of the Ureterocele in Neonatal Patients. 61
29552745 2018

Variations for Ureterocele

Expression for Ureterocele

Search GEO for disease gene expression data for Ureterocele.

Pathways for Ureterocele

Pathways related to Ureterocele according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.28 PTPRS PTPRF
2 9.83 PAX8 PAX2

GO Terms for Ureterocele

Biological processes related to Ureterocele according to GeneCards Suite gene sharing:

(show all 25)
# Name GO ID Score Top Affiliating Genes
1 dephosphorylation GO:0016311 9.79 PTPRS PTPRF PRUNE1
2 branching involved in ureteric bud morphogenesis GO:0001658 9.69 PAX8 PAX2 LHX1
3 metanephros development GO:0001656 9.62 PAX8 LHX1
4 spinal cord development GO:0021510 9.62 PTPRS LHX1
5 synaptic membrane adhesion GO:0099560 9.61 PTPRS PTPRF
6 mesonephric tubule development GO:0072164 9.6 PAX8 LHX1
7 mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9.59 PAX8 PAX2
8 regulation of metanephric nephron tubule epithelial cell differentiation GO:0072307 9.58 PAX8 PAX2
9 metanephric S-shaped body morphogenesis GO:0072284 9.58 PAX8 LHX1
10 metanephric epithelium development GO:0072207 9.57 PAX8 PAX2
11 metanephric nephron tubule formation GO:0072289 9.56 PAX8 PAX2
12 metanephric distal convoluted tubule development GO:0072221 9.55 PAX8 PAX2
13 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 9.54 PAX8 PAX2
14 S-shaped body morphogenesis GO:0072050 9.52 PAX8 LHX1
15 negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 9.49 PAX8 PAX2
16 metanephric comma-shaped body morphogenesis GO:0072278 9.48 PAX8 LHX1
17 positive regulation of metanephric DCT cell differentiation GO:2000594 9.46 PAX8 PAX2
18 negative regulation of apoptotic process involved in metanephric nephron tubule development GO:1900218 9.43 PAX8 PAX2
19 positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 9.43 PAX8 PAX2 LHX1
20 negative regulation of apoptotic process involved in metanephric collecting duct development GO:1900215 9.4 PAX8 PAX2
21 negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis GO:0072305 9.37 PAX8 PAX2
22 urogenital system development GO:0001655 9.33 PAX8 PAX2 LHX1
23 pronephric field specification GO:0039003 9.32 PAX8 PAX2
24 mesonephros development GO:0001823 9.13 PAX8 PAX2 LHX1
25 pronephros development GO:0048793 8.8 PAX8 PAX2 LHX1

Molecular functions related to Ureterocele according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 phosphatase activity GO:0016791 8.8 PTPRS PTPRF PRUNE1

Sources for Ureterocele

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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