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MCID: URT014
MIFTS: 42

Ureterolithiasis

Categories: Nephrological diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Ureterolithiasis

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MalaCards integrated aliases for Ureterolithiasis:

Name: Ureterolithiasis 12 43 15 17 71
Calculus of Ureter 12 32
Ureteric Calculus 12
Ureteral Calculi 71
Ureteric Stone 12

Classifications:

MalaCards categories:
Anatomical: Nephrological diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:14146
ICD9CM 34 592.1
MeSH 43 D053039
NCIt 49 C114696
SNOMED-CT 67 31054009 95573009
ICD10 32 N20.1
UMLS 71 C0041952 C1456865
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Summaries for Ureterolithiasis

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MalaCards based summary : Ureterolithiasis, also known as calculus of ureter, is related to pyuria and prostatic adenoma. An important gene associated with Ureterolithiasis is CHRM3 (Cholinergic Receptor Muscarinic 3), and among its related pathways/superpathways are Calcium signaling pathway and Myometrial Relaxation and Contraction Pathways. The drugs Alfuzosin and Sodium citrate have been mentioned in the context of this disorder. Affiliated tissues include kidney, prostate and liver, and related phenotype is cardiovascular system.

Wikipedia : 74 Kidney stone disease, also known as urolithiasis, is when a solid piece of material (kidney stone)... more...

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Related Diseases for Ureterolithiasis

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Diseases related to Ureterolithiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 161)
# Related Disease Score Top Affiliating Genes
1 pyuria 30.7 NEXMIF CRP
2 prostatic adenoma 30.4 ADRA1D ADRA1A
3 low compliance bladder 30.3 PDE5A CHRM3
4 prostatic hypertrophy 30.1 ADRA1D ADRA1A
5 impotence 30.1 PDE5A ADRA1D ADRA1A
6 ureteral disease 30.1 CRP CHRM3
7 priapism 30.0 PDE5A ADRA1A
8 nephrolithiasis, calcium oxalate 29.5 PTH PPARGC1B CRP CHRM3 APRT
9 hydronephrosis 10.6
10 ureteral obstruction 10.5
11 pyelonephritis 10.4
12 appendicitis 10.3
13 urethral stricture 10.3 PDE5A ADRA1D
14 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.3
15 toxic shock syndrome 10.3
16 ascending cholangitis 10.3 CRP CHRM3
17 physical urticaria 10.3 CRP CHRM3
18 back pain 10.2
19 acute cystitis 10.2
20 urinary tract obstruction 10.2
21 raynaud disease 10.2 PDE5A CRP
22 nasopharyngitis 10.2 PDE5A CRP
23 tricuspid valve insufficiency 10.2 PDE5A CRP
24 tricuspid valve disease 10.2 PDE5A CRP
25 plasma protein metabolism disease 10.2 CRP ADRA1D
26 ludwig's angina 10.1 NCBP3 CRP
27 vesicoureteral reflux 1 10.1
28 hyperparathyroidism 10.1
29 endometriosis 10.1
30 anuria 10.1
31 kidney disease 10.1
32 acute pyelonephritis 10.1
33 diverticulitis 10.1
34 47,xyy 10.1
35 male reproductive organ benign neoplasm 10.1 ADRA1D ADRA1A
36 mycobacterium tuberculosis 1 10.1
37 peritonitis 10.1
38 male infertility 10.1
39 constipation 10.1
40 gastroenteritis 10.1
41 pyelitis 10.1 NEXMIF CRP
42 functional gastric disease 10.1 PDE5A CRP
43 nerve compression syndrome 10.0 PTH CRP
44 triiodothyronine receptor auxiliary protein 10.0
45 prostatic hyperplasia, benign 10.0
46 leptin deficiency or dysfunction 10.0
47 visual epilepsy 10.0
48 bacteriuria 10.0
49 rectum cancer 10.0
50 chronic kidney disease 10.0

Comorbidity relations with Ureterolithiasis via Phenotypic Disease Network (PDN): (show all 12)


Acute Cystitis Bladder Neck Obstruction
Hydronephrosis Nephrolithiasis, Uric Acid
Nephrolithiasis, X-Linked Recessive, with Renal Failure Paralytic Ileus
Prostate Cancer Prostatic Hypertrophy
Pyelonephritis Urethral Calculus
Urethral Stricture Urinary Tract Obstruction

Graphical network of the top 20 diseases related to Ureterolithiasis:



Diseases related to Ureterolithiasis
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Symptoms & Phenotypes for Ureterolithiasis

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MGI Mouse Phenotypes related to Ureterolithiasis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.23 ADRA1A ADRA1D CHRM3 CHRM4 CRP NCBP3
Sources

Drugs & Therapeutics for Ureterolithiasis

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Drugs for Ureterolithiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 80)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Alfuzosin Approved, Investigational Phase 4 81403-80-7 2092
2
Sodium citrate Approved, Investigational Phase 4 68-04-2
3
Acetaminophen Approved Phase 4 103-90-2 1983
4
Ketoprofen Approved, Vet_approved Phase 4 22071-15-4 3825
5
Morphine Approved, Investigational Phase 4 57-27-2 5288826
6
Nefopam Approved, Investigational Phase 4 13669-70-0
7
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
8
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
9
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
10
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
11
Tamsulosin Approved, Investigational Phase 4 106133-20-4 129211
12
Silodosin Approved Phase 4 160970-54-7
13
Citric acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
14 Neurotransmitter Agents Phase 4
15 Adrenergic alpha-Antagonists Phase 4
16 Adrenergic Antagonists Phase 4
17 Adrenergic Agents Phase 4
18 Vasodilator Agents Phase 4
19 Phosphodiesterase Inhibitors Phase 4
20 Citrate Phase 4
21 Sildenafil Citrate Phase 4 171599-83-0
22 Phosphodiesterase 5 Inhibitors Phase 4
23 Antipyretics Phase 4
24 Pharmaceutical Solutions Phase 4
25 Antibiotics, Antitubercular Phase 4
26 Anti-Bacterial Agents Phase 4
27 Anti-Infective Agents Phase 4
28 Narcotics Phase 4
29 Analgesics, Opioid Phase 4
30 Ketorolac Tromethamine Phase 4
31 Cytochrome P-450 Enzyme Inhibitors Phase 4
32 Topoisomerase Inhibitors Phase 4
33 Cytochrome P-450 CYP1A2 Inhibitors Phase 4
34
Nifedipine Approved Phase 3 21829-25-4 4485
35
Doxazosin Approved Phase 3 74191-85-8 3157
36
Prazosin Approved Phase 3 19216-56-9 4893
37
Tramadol Approved, Investigational Phase 3 27203-92-5 33741
38
Aceclofenac Approved, Investigational Phase 3 89796-99-6
39
Calcium Approved, Nutraceutical Phase 3 7440-70-2 271
40 Naftopidil Investigational Phase 3 57149-07-2
41 Tocolytic Agents Phase 3
42 Antihypertensive Agents Phase 3
43 Platelet Aggregation Inhibitors Phase 3
44 calcium channel blockers Phase 3
45 Calcium, Dietary Phase 3
46
Mirabegron Approved Phase 2 223673-61-8 9865528
47 Adrenergic Agonists Phase 2
48 Adrenergic beta-3 Receptor Agonists Phase 2
49 Adrenergic beta-Agonists Phase 2
50
Ibuprofen Approved 15687-27-1 3672

Interventional clinical trials:

(show top 50) (show all 73)
# Name Status NCT ID Phase Drugs
1 Efficacy of Tamsulosin OCAS in the Conjunctive Medical Treatment of Distal Ureteral Stones.A Randomized, Double-blind, Placebo-controlled Study Unknown status NCT01167062 Phase 4 Tamsulosin Hydrochloride OCAS 0.4 mg
2 The Use of Medical-Expulsive Therapy With Alfuzocine xl 10mg x1/d for Distal Ureterolithiasis.a Randomized Prospective Study Unknown status NCT00489112 Phase 4 Alfuzocine XL 10 mg once a day
3 A Comparison Between Flexible Ureteroscopy, Semirigid Ureteroscopy and Extracorporeal Shockwaves Lithotripsy (SWL) in The Management of Proximal Ureteric Stones. A Randomized Controlled Trial Unknown status NCT02469766 Phase 4
4 Role of Phosphodiesterase 5 Inhibitors (PDE5i) (Sildenafil) in Management of Distal Ureteral Stone Unknown status NCT02519153 Phase 4 Sildenafil
5 The Efficacy of Alpha-blockers for Expulsion of Distal Ureteral Stones Unknown status NCT00451061 Phase 4 Alfuzosin;Tamsulosin
6 Interest of Néfopam in the Treatment of Pain During the Intense Ureteral Calculi Uncomplicated in Adults in Emergencies Unit. Completed NCT00639574 Phase 4 Néfopam
7 A 4-week, Double-blind, Randomized, Comparative and Multi-center Clinical Trial to Evaluate the Efficacy and Safety of Silodosin in the Treatment of Natural Expulsion in Patients With Ureteral Stones. Completed NCT01533389 Phase 4 Silodosin;Placebo
8 Study of Tamsulosin for Urolithiasis in the Emergency Department Completed NCT00382265 Phase 4 tamsulosin
9 A Double Blind, Multi-arm Randomized Control Trial, for Efficacy of Intramuscular Diclofenac Versus Intravenous Morphine Versus Intravenous Paracetamol, in Renal Colic Emergency Department Pain Management Completed NCT02187614 Phase 4 Diclofenac;Morphine;Paracetamol;Placebos
10 Study of Ketorolac Versus Opioid for Pain After Endoscopy (SKOPE): A Double-blinded Randomized Control Trial Comparing Outpatient Analgesic Efficacy of NSAIDs and Opioids in Patients Undergoing Ureteroscopy for Kidney Stones Recruiting NCT03888144 Phase 4 Oxycodone;Ketorolac
11 Efectividad de la Tamsulosina Como Tratamiento Adyuvante Previo a Ureterolitotomia Endoscopica Recruiting NCT03614052 Phase 4 Tamsulosin Hydrochloride 0.4 milligrams;Placebo Oral Tablet
12 A Multicenter Randomized Controlled Trial Assessing the Efficacy of Antimicrobial Prophylaxis for Extracorporeal Shock Wave Lithotripsy on Reducing Urinary Tract Infection Recruiting NCT03692715 Phase 4 Ciprofloxacin;Placebo
13 Comparison of Silodosin vs. Tamsulosin on Spontaneous Passage of Acutely Obstructing Ureteral Calculi in Medical Expulsive Therapy Terminated NCT02369744 Phase 4 Silodosin;Tamsulosin
14 Celecoxib in the Management of Acute Renal Colic Withdrawn NCT00304317 Phase 4 celecoxib
15 Evaluation of Alfuzosin as Medical Expulsion Therapy for Ureteral Stones Unknown status NCT00713739 Phase 3 Alfuzosin;nifedipine;doxazosin;prazosin
16 Alfuzosin Hydrochloride to Promote Passage of Distal Ureteral Calculi Completed NCT00177086 Phase 3
17 Medical Expulsive Therapy for Ureter Stone Using Naftopidil: Multicenter, Randomized, Double-blind, Placebo Controlled Study Completed NCT01952314 Phase 3 Naftopidil 75mg;Placebo for Naftopidil;Standard treatment
18 Interest of a Treatment With the alpha1-blocker Tamsulosin in the Elimination of Pelvis Ureteral Stones Completed NCT00151567 Phase 3 Tamsulosin;Placebo
19 Phase II Study Comparing Two Groups of Patients Undergoing ESWL Treated With Ureteral Stents Versus Expulsion Therapy With Tamsulosin Unknown status NCT00478998 Phase 2 Tamsulosin
20 Prospective Randomized Placebo Controlled Blinded Study to Evaluate the Efficacy of Alfuzosin (Alpha Blocker) on the Success Rates Following SWL. Unknown status NCT00409227 Phase 2 Alpha blocker-alfuzosin;placebo
21 A Double-Blind, Placebo-Controlled Study of Silodosin to Facilitate Urinary Stone Passage Completed NCT01144949 Phase 2 silodosin;placebo
22 A Double Blind Placebo Control Trial of Mirabegron for Medical Expulsive Therapy and to Manage Stent Pain for Ureteral Stones(Protocol # 01-16-20-02) Recruiting NCT02744430 Phase 2 Mirabegron
23 URIPRENE: Feasibility Study to Evaluate the Preliminary Safety and Effectiveness of the Uriprene Stent Following Uncomplicated Ureteroscopy Completed NCT02032316 Phase 1
24 The Use of Tamsulosin in Treatment of (10-15 mm) Lower Ureteric Stones in Adults With Non-emergent Symptoms: A Prospective Randomized Study Unknown status NCT03274700 Early Phase 1 Tamsulosin.;Placebo.
25 Prospective Comparison Between Different Laser Settings for Ureteral \ Kidney Stones Treatment During Unknown status NCT02279927
26 Shockwave Lithotripsy (SWL) Under Regular General Anesthesia and Under General Anesthesia Using Bronchial Blocker. Unknown status NCT01008267
27 The Impact of Silent Ureteral Stone on Renal Function and Kidney Anatomy: a Prospective Analysis Unknown status NCT01884870
28 Comparative Study in Patients With Lower Ureteral Stones Treated With 10 MG Alfuzosin,10 MG Alfuzosin With Rowatinex, and Rowatinex Alone Unknown status NCT00397397
29 Intraureteral of Alkalinized Lidocaine as Novel Approach to Post-Ureteroscopy Pain: Double-blind Prospective Randomized Controlled Trial Unknown status NCT01450566 Lidocaine;Saline
30 Comparison Between Symptomps Related to Positioning a Hydrophilic Vortek Double J and a Silicone Double J at the End of a URS for Ureteral Lithiasis Unknown status NCT03344120
31 Ultrasound Non-contrast Computed Tomography Real-time Fusion for Urinary Stones Follow up Unknown status NCT02539004
32 Staged Ureteroscopy After Initial Urinary Drainage Versus Direct Ureteroscopy in the Treatment of Pediatric Obstructive Calcular Anuria Unknown status NCT02139059
33 Ultrasound Imaging of Kidney Stones and Lithotripsy Unknown status NCT02214836
34 Impact of Low Dose Fluoroscopy in Ureteroscopy Unknown status NCT02704949
35 The Alternating Bidirectional Versus The Standard Approach During Shock Wave Lithotripsy For Renal And Upper Lumbar Ureteric Stones. A Randomized Clinical Trial Unknown status NCT03243682
36 The Influence of Super-Mini Percutaneous Nephrolithotomy on Renal Pelvic Pressure In Vivo Unknown status NCT02760134
37 The Use of Non-contrast Helical Computerized Tomogram in Predicting Treatment Outcome of Upper Ureteric Stone by Extracorporeal Shock Wave Lithotripsy Using the Sonolith 4000+ Lithotripter Completed NCT00517205
38 Ultraslow Full-power SWL Versus Slow SWL in Stones With High Attenuation Value Completed NCT03795545
39 Is Prophylactic Antibiotics Necessary In Otherwise Healthy Adult Patients Undergoing Ureteroscopic Procedures for Ureteral Stones? Completed NCT02635490
40 Comparing Uretersocopy With Versus Without Use of Guide-wire in Treatment of Ureteral Stone Completed NCT03726502
41 The Role of Flexible Cystoscopy in Laparoscopic Stone Surgery: a Single Surgeon Experience Completed NCT01277198
42 Evaluation of Ureteral Length Measurement by Computed Tomography (CT) to Actual Ureteral Length Measured by Ureteral Catheterization Completed NCT01542593
43 The Predictive Value of Ureteral Jet Assessment With Ultrasound in Patients Presenting With Acute Renal Colic Completed NCT02577146
44 Medical Expulsive Therapy of Single Distal Ureteral Stones. A Randomised, Double-blind and Placebo-controlled Study Completed NCT00831701 Tamsulosin;Placebo
45 Effect of Tamsulosin on Stone Expulsion and Pain Resolution in ED Patients With Ureterolithiasis Completed NCT00762424 Flowmax;placebo
46 Comparative Study of Extracorporeal Shock Wave Lithotripsy and Ureteroscopy in Management of Upper Third Ureteral Calculi Completed NCT03559738
47 Ureteral Stents Versus Percutaneous Nephrostomy for Initial Urinary Drainage in Children With Obstructive Anuria and Acute Renal Failure Due to Ureteral Calculi: a Prospective, Randomized Study Completed NCT02055430
48 The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients Completed NCT00600405 tamsulosin;Standard therapy with ibuprofen and oxycodone.
49 Use of the PercSys MicroStent Device to Alleviate Ureteral Stone Symptoms and Hydronephrosis Completed NCT01637519
50 Management of Ureteral Calculi Using Ultrasound Guidance: A Radiation Free Approach Completed NCT01792765

Search NIH Clinical Center for Ureterolithiasis

Cochrane evidence based reviews: ureterolithiasis

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Genetic Tests for Ureterolithiasis

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Anatomical Context for Ureterolithiasis

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MalaCards organs/tissues related to Ureterolithiasis:

40
Kidney, Prostate, Liver, Bone, Neutrophil, Brain, Colon
Sources

Publications for Ureterolithiasis

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Articles related to Ureterolithiasis:

(show top 50) (show all 327)
# Title Authors PMID Year
1
Boari-Flap reconstrution due to a total ureteral avulsion in a patient with ipslateral ureterolithiasis and contralateral renal nodule. 61
32025494 2020
2
Comparison of the Diagnostic Values of Leukocytes, Neutrophils, Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Distinguishing between Acute Appendicitis and Right Ureterolithiasis. 61
32013359 2020
3
Ultra-Low-Dose CT: An Effective Follow-Up Imaging Modality for Ureterolithiasis. 61
31663371 2020
4
Renal Forniceal Rupture in the Setting of Obstructing Ureteral Stones (FROU): An Analysis of Stone Characterization and Urologic Intervention Pattern. 61
31950872 2020
5
Effectiveness of medical expulsive therapy with the ɲ-adrenergic blocker tamsulosin for distal ureterolithiasis in adults attended in an emergency department in Chile. 61
31777212 2019
6
Narcotic Pain Control for Ureterolithiasis Is Associated With Unnecessary Repeat Imaging in the Emergency Department. 61
30358635 2019
7
[Abdominal ultrasound in emergency and critical care medicine]. 61
30840096 2019
8
Dynamic thiol/disulfide homeostasis as a novel indicator of oxidative stress in patients with urolithiasis. 61
31294135 2019
9
Identification of ureteral stones at reduced radiation exposure: a pilot study comparing conventional versus digital low-dosage linear slot scanning (Lodox®) radiography. 61
31165230 2019
10
Limited sensitivity and size over measurements of ultrasound affect medical decisions for ureteral stone compared to non-contrasted computed tomography. 61
30109485 2019
11
Medical and Interventional Management of Upper Urinary Tract Uroliths. 61
30736892 2019
12
Unconventional natural gas development and hospitalizations: evidence from Pennsylvania, United States, 2003-2014. 61
30677623 2019
13
Clinical Effects of Polymyxin B Hemoperfusion in Patients With Septic Shock Caused by Urinary Tract Infection. 61
30209889 2019
14
Early ureteroscopic treatment in patients with urosepsis associated with ureteral calculi is a safe approach. A pilot study. 61
31482023 2019
15
Re: Minimizing the Cost of Treating Asymptomatic Ureterolithiasis. 61
30577359 2019
16
Interest of URS-L in the Treatment of Ureterolithiasis in Preschool Children. 61
31555620 2019
17
Ureterolithiasis and the quest for rational use of diagnostic imaging methods. 61
30559568 2018
18
Use of a subcutaneous ureteral bypass device for treatment of benign ureteral obstruction in cats: 174 ureters in 134 cats (2009-2015). 61
30398425 2018
19
Bilateral ureterolithiasis: A true positive and false negative PoCUS exam in a patient with renal colic. 61
29606152 2018
20
Acute synchronous appendicitis and obstructing ureterolithiasis. 61
30108673 2018
21
CONTACT ULTRASOUND LITHOTRIPSY DURING URETEROLITHIASIS THERAPY. AN ANALYSIS OF LATE POSTOPERATIVE COMPLICATIONS. 61
30358535 2018
22
Epidemiological and imaging features that can affect the detection of ureterolithiasis on ultrasound. 61
30369654 2018
23
Perinephric Fat Stranding Is Associated with Elevated Creatinine Among Patients with Acutely Obstructing Ureterolithiasis. 61
29943669 2018
24
Does fasting in Ramadan increase the risk of developing urinary stones? 61
29738008 2018
25
Outcome of ureteral stent placement for treatment of benign ureteral obstruction in dogs: 44 cases (2010-2013). 61
29504861 2018
26
[Results of laparoscopic ureterolithotomy depending on the type of laparoscopic approach and location of the stone]. 61
29634145 2018
27
Predictive value of secondary signs of obstruction in follow-up computed tomography of ureteral stones: a study with dynamic computed tomography. 61
29037128 2018
28
Differential diagnoses of magnetic resonance imaging for suspected acute appendicitis in pregnant patients. 61
29290892 2018
29
Treatment of fungal pyelonephritis and ureterolithiasis with a subcutaneous ureteral bypass system and systemic antifungal medication in a cat. 61
30568915 2018
30
An Accurate Diagnostic Pathway Helps to Correctly Distinguish Between the Possible Causes of Acute Scrotum. 61
29468000 2018
31
Influence of acetylsalicylic acid and low-molecular weight heparins on the formation of renal hematoma after shock wave lithotripsy. 61
28702844 2017
32
[Biomarkers of renal injury in contact ureteral lithotripsy]. 61
29135147 2017
33
Emergency Ureteral Stone Treatment Score Predicts Outcomes of Ureteroscopic Intervention in Acute Obstructive Uropathy Secondary to Urolithiasis. 61
28637368 2017
34
Comparison between double-pigtail ureteral stents and ureteral bypass devices for treatment of ureterolithiasis in cats. 61
28763282 2017
35
Different Approaches to Detect "Nanobacteria" in Patients with Kidney Stones: an Infectious Cause or a Subset of Life? 61
28853105 2017
36
Medical expulsive therapy use in emergency department patients diagnosed with ureteral stones. 61
28291706 2017
37
Case control study: hyperbaric oxygen treatment of mild traumatic brain injury persistent post-concussion syndrome and post-traumatic stress disorder. 61
29152209 2017
38
[Questions of terminology, systematization and grading of complications of contact ureteral lithotripsy]. 61
28845938 2017
39
Imaging of Acute Pelvic Pain in Girls: Ovarian Torsion and Beyond☆. 61
28185689 2017
40
A Comparison of Urolithiasis in the Presence and Absence of Microscopic Hematuria in the Emergency Department. 61
28611901 2017
41
Perioperative Occlusion of a Subcutaneous Ureteral Bypass Secondary to a Severe Pyonephrosis in a Birman Cat. 61
28992905 2017
42
Ureterolithiasis: Management in an environment with limited facilities. 61
28513524 2017
43
Medical Expulsive Therapy for Ureterolithiasis: The EAU Recommendations in 2016. 61
27506951 2017
44
Can Doppler ultrasonography twinkling artifact be used as an alternative imaging modality to non-contrast-enhanced computed tomography in patients with ureteral stones? A prospective clinical study. 61
27170278 2017
45
Glomerular filtration rate determination by computed tomography in two pet rabbits with renal disease. 61
28263109 2017
46
Comparison of prone vs. supine unenhanced CT imaging in patients with clinically suspected ureterolithiasis. 61
27670877 2017
47
Paediatric ureterolithotripsy: Tips and tricks - Experience at a single center. 61
29487266 2017
48
Spontaneous proximal ureteric rupture secondary to ureterolithiasis. 61
28069871 2017
49
The Diagnosis and Management of Patients with Renal Colic across a Sample of US Hospitals: High CT Utilization Despite Low Rates of Admission and Inpatient Urologic Intervention. 61
28046001 2017
50
[Extracorporeal and contact lithotripsy for large ureteral stones]. 61
28248059 2016
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Variations for Ureterolithiasis

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Expression for Ureterolithiasis

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Search GEO for disease gene expression data for Ureterolithiasis.
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Pathways for Ureterolithiasis

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Pathways related to Ureterolithiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Calcium signaling pathway 36
Show member pathways
 11.79 CHRM3 ADRA1D ADRA1A
2
Myometrial Relaxation and Contraction Pathways 1
Show member pathways
 11.75 CHRM4 CHRM3 ADRA1D ADRA1A
3
Salivary secretion 36
Show member pathways
 11.65 CHRM3 ADRA1D ADRA1A
4
Monoamine GPCRs 1
Show member pathways
 10.97 CHRM4 CHRM3 ADRA1D ADRA1A
5
Sympathetic Nerve Pathway (Neuroeffector Junction) 60
10.52 ADRA1D ADRA1A
Sources

GO Terms for Ureterolithiasis

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Biological processes related to Ureterolithiasis according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 G protein-coupled receptor signaling pathway GO:0007186 9.93 PTH CHRM4 CHRM3 ADRA1D ADRA1A
2 cell-cell signaling GO:0007267 9.7 PTH ADRA1D ADRA1A
3 positive regulation of vasoconstriction GO:0045907 9.51 ADRA1D ADRA1A
4 G protein-coupled serotonin receptor signaling pathway GO:0098664 9.49 CHRM4 CHRM3
5 activation of phospholipase C activity GO:0007202 9.48 PTH ADRA1A
6 positive regulation of cardiac muscle hypertrophy GO:0010613 9.46 PDE5A ADRA1A
7 regulation of vasoconstriction GO:0019229 9.43 CHRM3 ADRA1A
8 adenylate cyclase-activating adrenergic receptor signaling pathway GO:0071880 9.4 ADRA1D ADRA1A
9 smooth muscle contraction GO:0006939 9.37 CHRM3 ADRA1A
10 G protein-coupled acetylcholine receptor signaling pathway GO:0007213 9.32 CHRM4 CHRM3
11 adrenergic receptor signaling pathway GO:0071875 9.26 ADRA1D ADRA1A
12 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway GO:0007197 9.16 CHRM4 CHRM3
13 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001994 8.96 ADRA1D ADRA1A
14 positive regulation of smooth muscle contraction GO:0045987 8.8 CHRM3 ADRA1D ADRA1A

Molecular functions related to Ureterolithiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neurotransmitter receptor activity GO:0030594 9.32 CHRM4 CHRM3
2 G protein-coupled serotonin receptor activity GO:0004993 9.26 CHRM4 CHRM3
3 adrenergic receptor activity GO:0004935 9.16 ADRA1D ADRA1A
4 G protein-coupled acetylcholine receptor activity GO:0016907 8.96 CHRM4 CHRM3
5 alpha1-adrenergic receptor activity GO:0004937 8.62 ADRA1D ADRA1A
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Sources for Ureterolithiasis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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