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MCID: URT014
MIFTS: 44

Ureterolithiasis

Categories: Nephrological diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Ureterolithiasis

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MalaCards integrated aliases for Ureterolithiasis:

Name: Ureterolithiasis 12 43 15 17 71
Calculus of Ureter 12 32
Ureteric Calculus 12
Ureteral Calculi 71
Ureteric Stone 12

Classifications:

MalaCards categories:
Anatomical: Nephrological diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:14146
ICD9CM 34 592.1
MeSH 43 D053039
NCIt 49 C114696
SNOMED-CT 67 31054009
ICD10 32 N20.1
UMLS 71 C0041952 C1456865
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Summaries for Ureterolithiasis

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Disease Ontology : 12 An ureteral disease this is characterized by the formation of stoney concentrations in the ureter.

MalaCards based summary : Ureterolithiasis, also known as calculus of ureter, is related to prostatic adenoma and impotence. An important gene associated with Ureterolithiasis is APRT (Adenine Phosphoribosyltransferase), and among its related pathways/superpathways are Calcium signaling pathway and Myometrial Relaxation and Contraction Pathways. The drugs Alfuzosin and Sodium citrate have been mentioned in the context of this disorder. Affiliated tissues include kidney, neutrophil and brain, and related phenotype is cardiovascular system.

Wikipedia : 74 Kidney stone disease, also known as nephrolithiasis or urolithiasis, is when a solid piece of material... more...

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Related Diseases for Ureterolithiasis

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Diseases related to Ureterolithiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 176)
# Related Disease Score Top Affiliating Genes
1 prostatic adenoma 30.7 ADRA1D ADRA1A
2 impotence 30.3 PDE5A ADRA1D ADRA1A
3 low compliance bladder 30.2 PDE5A CHRM3
4 prostatic hypertrophy 30.2 PDE5A ADRA1D ADRA1A
5 priapism 30.1 PDE5A ADRA1A
6 pure autonomic failure 29.8 TTR PDE5A
7 hydronephrosis 10.6
8 nephrolithiasis 10.6
9 ureteral obstruction 10.5
10 urolithiasis 10.5
11 pyelonephritis 10.4
12 male reproductive organ benign neoplasm 10.3 ADRA1D ADRA1A
13 appendicitis 10.3
14 toxic shock syndrome 10.3
15 pyuria 10.3
16 coronary artery vasospasm 10.3 CRP ADRA1A
17 urethral stricture 10.2 PDE5A ADRA1D
18 dental abscess 10.2 PTH CRP
19 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.2
20 back pain 10.2
21 acute cystitis 10.2
22 urinary tract obstruction 10.2
23 pulmonary valve insufficiency 10.2 PDE5A CRP
24 raynaud disease 10.2 PDE5A CRP
25 nephrolithiasis, calcium oxalate 10.1
26 vesicoureteral reflux 1 10.1
27 hyperparathyroidism 10.1
28 endometriosis 10.1
29 anuria 10.1
30 kidney disease 10.1
31 acute pyelonephritis 10.1
32 diverticulitis 10.1
33 47,xyy 10.1
34 ludwig's angina 10.1 NCBP3 CRP
35 mycobacterium tuberculosis 1 10.1
36 peritonitis 10.1
37 male infertility 10.1
38 constipation 10.1
39 gastroenteritis 10.1
40 nasopharyngitis 10.1 PDE5A CRP
41 tricuspid valve insufficiency 10.1 PDE5A CRP
42 tricuspid valve disease 10.1 PDE5A CRP
43 sexual disorder 10.1 PDE5A ADRA1D ADRA1A
44 renal tuberculosis 10.1 NEXMIF CRP
45 urogenital tuberculosis 10.1 NEXMIF CRP
46 triiodothyronine receptor auxiliary protein 10.0
47 prostatic hyperplasia, benign 10.0
48 leptin deficiency or dysfunction 10.0
49 visual epilepsy 10.0
50 bacteriuria 10.0

Comorbidity relations with Ureterolithiasis via Phenotypic Disease Network (PDN): (show all 12)


Acute Cystitis Bladder Neck Obstruction
Hydronephrosis Nephrolithiasis, Uric Acid
Nephrolithiasis, X-Linked Recessive, with Renal Failure Paralytic Ileus
Prostate Cancer Prostatic Hypertrophy
Pyelonephritis Urethral Calculus
Urethral Stricture Urinary Tract Obstruction

Graphical network of the top 20 diseases related to Ureterolithiasis:



Diseases related to Ureterolithiasis
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Symptoms & Phenotypes for Ureterolithiasis

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MGI Mouse Phenotypes related to Ureterolithiasis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.28 ADRA1A ADRA1D CHRM3 CHRM4 CRP NCBP3
Sources

Drugs & Therapeutics for Ureterolithiasis

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Drugs for Ureterolithiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 74)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Alfuzosin Approved, Investigational Phase 4 81403-80-7 2092
2
Sodium citrate Approved, Investigational Phase 4 68-04-2
3
Acetaminophen Approved Phase 4 103-90-2 1983
4
Ketoprofen Approved, Vet_approved Phase 4 22071-15-4 3825
5
Morphine Approved, Investigational Phase 4 57-27-2 5288826
6
Nefopam Approved, Investigational Phase 4 13669-70-0
7
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
8
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
9
Ketorolac Approved Phase 4 66635-83-4, 74103-06-3 3826
10
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
11
Tamsulosin Approved, Investigational Phase 4 106133-20-4 129211
12
Silodosin Approved Phase 4 160970-54-7
13
Citric acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
14 Adrenergic alpha-Antagonists Phase 4
15 Adrenergic Agents Phase 4
16 Adrenergic Antagonists Phase 4
17 Neurotransmitter Agents Phase 4
18 Adrenergic alpha-1 Receptor Antagonists Phase 4
19 Phosphodiesterase Inhibitors Phase 4
20 Citrate Phase 4
21 Phosphodiesterase 5 Inhibitors Phase 4
22 Vasodilator Agents Phase 4
23 Sildenafil Citrate Phase 4 171599-83-0
24 Antipyretics Phase 4
25 Pharmaceutical Solutions Phase 4
26 Anti-Bacterial Agents Phase 4
27 Antibiotics, Antitubercular Phase 4
28 Narcotics Phase 4
29 Analgesics, Opioid Phase 4
30 Cytochrome P-450 Enzyme Inhibitors Phase 4
31 Anti-Infective Agents Phase 4
32
Doxazosin Approved Phase 3 74191-85-8 3157
33
Nifedipine Approved Phase 3 21829-25-4 4485
34
Prazosin Approved Phase 3 19216-56-9 4893
35
Aceclofenac Approved, Investigational Phase 3 89796-99-6
36
Tramadol Approved, Investigational Phase 3 27203-92-5 33741
37 Naftopidil Investigational Phase 3 57149-07-2
38 Tocolytic Agents Phase 3
39 Antihypertensive Agents Phase 3
40 Hormones Phase 3
41 Platelet Aggregation Inhibitors Phase 3
42 Calcium, Dietary Phase 3
43 calcium channel blockers Phase 3
44
Calcium Nutraceutical Phase 3 7440-70-2 271
45
Mirabegron Approved Phase 2 223673-61-8 9865528
46 Adrenergic beta-Agonists Phase 2
47 Adrenergic Agonists Phase 2
48 Adrenergic beta-3 Receptor Agonists Phase 2
49
Lidocaine Approved, Vet_approved 137-58-6 3676
50
Levobupivacaine Approved, Investigational 27262-47-1 92253

Interventional clinical trials:

(show top 50) (show all 73)
# Name Status NCT ID Phase Drugs
1 Efficacy of Tamsulosin OCAS in the Conjunctive Medical Treatment of Distal Ureteral Stones.A Randomized, Double-blind, Placebo-controlled Study Unknown status NCT01167062 Phase 4 Tamsulosin Hydrochloride OCAS 0.4 mg
2 The Use of Medical-Expulsive Therapy With Alfuzocine xl 10mg x1/d for Distal Ureterolithiasis.a Randomized Prospective Study Unknown status NCT00489112 Phase 4 Alfuzocine XL 10 mg once a day
3 A Comparison Between Flexible Ureteroscopy, Semirigid Ureteroscopy and Extracorporeal Shockwaves Lithotripsy (SWL) in The Management of Proximal Ureteric Stones. A Randomized Controlled Trial Unknown status NCT02469766 Phase 4
4 Role of Phosphodiesterase 5 Inhibitors (PDE5i) (Sildenafil) in Management of Distal Ureteral Stone Unknown status NCT02519153 Phase 4 Sildenafil
5 The Efficacy of Alpha-blockers for Expulsion of Distal Ureteral Stones Unknown status NCT00451061 Phase 4 Alfuzosin;Tamsulosin
6 Interest of Néfopam in the Treatment of Pain During the Intense Ureteral Calculi Uncomplicated in Adults in Emergencies Unit. Completed NCT00639574 Phase 4 Néfopam
7 A 4-week, Double-blind, Randomized, Comparative and Multi-center Clinical Trial to Evaluate the Efficacy and Safety of Silodosin in the Treatment of Natural Expulsion in Patients With Ureteral Stones. Completed NCT01533389 Phase 4 Silodosin;Placebo
8 Study of Tamsulosin for Urolithiasis in the Emergency Department Completed NCT00382265 Phase 4 tamsulosin
9 A Double Blind, Multi-arm Randomized Control Trial, for Efficacy of Intramuscular Diclofenac Versus Intravenous Morphine Versus Intravenous Paracetamol, in Renal Colic Emergency Department Pain Management Completed NCT02187614 Phase 4 Diclofenac;Morphine;Paracetamol;Placebos
10 Study of Ketorolac Versus Opioid for Pain After Endoscopy (SKOPE): A Double-blinded Randomized Control Trial Comparing Outpatient Analgesic Efficacy of NSAIDs and Opioids in Patients Undergoing Ureteroscopy for Kidney Stones Recruiting NCT03888144 Phase 4 Oxycodone;Ketorolac
11 A Multicenter Randomized Controlled Trial Assessing the Efficacy of Antimicrobial Prophylaxis for Extracorporeal Shock Wave Lithotripsy on Reducing Urinary Tract Infection Recruiting NCT03692715 Phase 4 Ciprofloxacin;Placebo
12 Efectividad de la Tamsulosina Como Tratamiento Adyuvante Previo a Ureterolitotomia Endoscopica Terminated NCT03614052 Phase 4 Tamsulosin Hydrochloride 0.4 milligrams;Placebo Oral Tablet
13 Comparison of Silodosin vs. Tamsulosin on Spontaneous Passage of Acutely Obstructing Ureteral Calculi in Medical Expulsive Therapy Terminated NCT02369744 Phase 4 Silodosin;Tamsulosin
14 Celecoxib in the Management of Acute Renal Colic Withdrawn NCT00304317 Phase 4 celecoxib
15 Evaluation of Alfuzosin as Medical Expulsion Therapy for Ureteral Stones Unknown status NCT00713739 Phase 3 Alfuzosin;nifedipine;doxazosin;prazosin
16 Alfuzosin Hydrochloride to Promote Passage of Distal Ureteral Calculi Completed NCT00177086 Phase 3
17 Medical Expulsive Therapy for Ureter Stone Using Naftopidil: Multicenter, Randomized, Double-blind, Placebo Controlled Study Completed NCT01952314 Phase 3 Naftopidil 75mg;Placebo for Naftopidil;Standard treatment
18 Interest of a Treatment With the alpha1-blocker Tamsulosin in the Elimination of Pelvis Ureteral Stones Completed NCT00151567 Phase 3 Tamsulosin;Placebo
19 Phase II Study Comparing Two Groups of Patients Undergoing ESWL Treated With Ureteral Stents Versus Expulsion Therapy With Tamsulosin Unknown status NCT00478998 Phase 2 Tamsulosin
20 Prospective Randomized Placebo Controlled Blinded Study to Evaluate the Efficacy of Alfuzosin (Alpha Blocker) on the Success Rates Following SWL. Unknown status NCT00409227 Phase 2 Alpha blocker-alfuzosin;placebo
21 A Double-Blind, Placebo-Controlled Study of Silodosin to Facilitate Urinary Stone Passage Completed NCT01144949 Phase 2 silodosin;placebo
22 A Double Blind Placebo Control Trial of Mirabegron for Medical Expulsive Therapy and to Manage Stent Pain for Ureteral Stones(Protocol # 01-16-20-02) Completed NCT02744430 Phase 2 Mirabegron
23 URIPRENE: Feasibility Study to Evaluate the Preliminary Safety and Effectiveness of the Uriprene Stent Following Uncomplicated Ureteroscopy Completed NCT02032316 Phase 1
24 The Use of Tamsulosin in Treatment of (10-15 mm) Lower Ureteric Stones in Adults With Non-emergent Symptoms: A Prospective Randomized Study Unknown status NCT03274700 Early Phase 1 Tamsulosin.;Placebo.
25 Ultrasound Guided Ureteroscopy for the Treatment of Lower Third Ureteric Stones in Adults Unknown status NCT03404986
26 Prospective Comparison Between Different Laser Settings for Ureteral \ Kidney Stones Treatment During Unknown status NCT02279927
27 Shockwave Lithotripsy (SWL) Under Regular General Anesthesia and Under General Anesthesia Using Bronchial Blocker. Unknown status NCT01008267
28 The Impact of Silent Ureteral Stone on Renal Function and Kidney Anatomy: a Prospective Analysis Unknown status NCT01884870
29 Comparative Study in Patients With Lower Ureteral Stones Treated With 10 MG Alfuzosin,10 MG Alfuzosin With Rowatinex, and Rowatinex Alone Unknown status NCT00397397
30 Intraureteral of Alkalinized Lidocaine as Novel Approach to Post-Ureteroscopy Pain: Double-blind Prospective Randomized Controlled Trial Unknown status NCT01450566 Lidocaine;Saline
31 Comparison Between Symptomps Related to Positioning a Hydrophilic Vortek Double J and a Silicone Double J at the End of a URS for Ureteral Lithiasis Unknown status NCT03344120
32 Ultrasound Non-contrast Computed Tomography Real-time Fusion for Urinary Stones Follow up Unknown status NCT02539004
33 Staged Ureteroscopy After Initial Urinary Drainage Versus Direct Ureteroscopy in the Treatment of Pediatric Obstructive Calcular Anuria Unknown status NCT02139059
34 Ultrasound Imaging of Kidney Stones and Lithotripsy Unknown status NCT02214836
35 Impact of Low Dose Fluoroscopy in Ureteroscopy Unknown status NCT02704949
36 The Alternating Bidirectional Versus The Standard Approach During Shock Wave Lithotripsy For Renal And Upper Lumbar Ureteric Stones. A Randomized Clinical Trial Unknown status NCT03243682
37 Intraluminal Ureteric Injection of High Concentration Alkalinised Long-acting Local Anaesthetic and STeroid Post urEteroscopy: A Prospective Double Blinded Randomised Controlled Trial (LASTE Trial) Unknown status NCT03296189 Levobupivacaine;Dexamethasone Sodium Phosphate;Placebos
38 The Influence of Super-Mini Percutaneous Nephrolithotomy on Renal Pelvic Pressure In Vivo Unknown status NCT02760134
39 The Use of Non-contrast Helical Computerized Tomogram in Predicting Treatment Outcome of Upper Ureteric Stone by Extracorporeal Shock Wave Lithotripsy Using the Sonolith 4000+ Lithotripter Completed NCT00517205
40 Ultraslow Full-power SWL Versus Slow SWL in Stones With High Attenuation Value Completed NCT03795545
41 Is Prophylactic Antibiotics Necessary In Otherwise Healthy Adult Patients Undergoing Ureteroscopic Procedures for Ureteral Stones? Completed NCT02635490
42 The Role of Flexible Cystoscopy in Laparoscopic Stone Surgery: a Single Surgeon Experience Completed NCT01277198
43 Comparing Uretersocopy With Versus Without Use of Guide-wire in Treatment of Ureteral Stone Completed NCT03726502
44 The Predictive Value of Ureteral Jet Assessment With Ultrasound in Patients Presenting With Acute Renal Colic Completed NCT02577146
45 Evaluation of Ureteral Length Measurement by Computed Tomography (CT) to Actual Ureteral Length Measured by Ureteral Catheterization Completed NCT01542593
46 Medical Expulsive Therapy of Single Distal Ureteral Stones. A Randomised, Double-blind and Placebo-controlled Study Completed NCT00831701 Tamsulosin;Placebo
47 Effect of Tamsulosin on Stone Expulsion and Pain Resolution in ED Patients With Ureterolithiasis Completed NCT00762424 Flowmax;placebo
48 Comparative Study of Extracorporeal Shock Wave Lithotripsy and Ureteroscopy in Management of Upper Third Ureteral Calculi Completed NCT03559738
49 Ureteral Stents Versus Percutaneous Nephrostomy for Initial Urinary Drainage in Children With Obstructive Anuria and Acute Renal Failure Due to Ureteral Calculi: a Prospective, Randomized Study Completed NCT02055430
50 The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients Completed NCT00600405 tamsulosin;Standard therapy with ibuprofen and oxycodone.

Search NIH Clinical Center for Ureterolithiasis

Cochrane evidence based reviews: ureterolithiasis

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Genetic Tests for Ureterolithiasis

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Anatomical Context for Ureterolithiasis

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MalaCards organs/tissues related to Ureterolithiasis:

40
Kidney, Neutrophil, Brain, Colon, Liver, Adrenal Gland, Ovary
Sources

Publications for Ureterolithiasis

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Articles related to Ureterolithiasis:

(show top 50) (show all 331)
# Title Authors PMID Year
1
Boari-Flap reconstrution due to a total ureteral avulsion in a patient with ipslateral ureterolithiasis and contralateral renal nodule. 61
32025494 2020
2
Uretero-Cutaneous Fistula and Renal Abscessation as a Complication of Ureteral Stenting in a Dog. 61
32182106 2020
3
Outcome of SUB placement for the treatment of benign ureteral obstruction in dogs: nine dogs and 12 renal units (2013 to 2017). 61
32352170 2020
4
Identification of ureteral stones at reduced radiation exposure: a pilot study comparing conventional versus digital low-dosage linear slot scanning (Lodox®) radiography. 61
31165230 2020
5
Renal Forniceal Rupture in the Setting of Obstructing Ureteral Stones: An Analysis of Stone Characterization and Urologic Intervention Pattern. 61
31950872 2020
6
Ultra-Low-Dose CT: An Effective Follow-Up Imaging Modality for Ureterolithiasis. 61
31663371 2020
7
Shared Decision Making in Patients With Suspected Uncomplicated Ureterolithiasis: A Decision Aid Development Study. 61
32064724 2020
8
Comparison of the Diagnostic Values of Leukocytes, Neutrophils, Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Distinguishing between Acute Appendicitis and Right Ureterolithiasis. 61
32013359 2020
9
Effectiveness of medical expulsive therapy with the ɲ-adrenergic blocker tamsulosin for distal ureterolithiasis in adults attended in an emergency department in Chile. 61
31777212 2019
10
Renal Tuberculosis: The Masquerader. 61
32041921 2019
11
[Abdominal ultrasound in emergency and critical care medicine]. 61
30840096 2019
12
Narcotic Pain Control for Ureterolithiasis Is Associated With Unnecessary Repeat Imaging in the Emergency Department. 61
30358635 2019
13
Dynamic thiol/disulfide homeostasis as a novel indicator of oxidative stress in patients with urolithiasis. 61
31294135 2019
14
Limited sensitivity and size over measurements of ultrasound affect medical decisions for ureteral stone compared to non-contrasted computed tomography. 61
30109485 2019
15
Medical and Interventional Management of Upper Urinary Tract Uroliths. 61
30736892 2019
16
Unconventional natural gas development and hospitalizations: evidence from Pennsylvania, United States, 2003-2014. 61
30677623 2019
17
Clinical Effects of Polymyxin B Hemoperfusion in Patients With Septic Shock Caused by Urinary Tract Infection. 61
30209889 2019
18
Interest of URS-L in the Treatment of Ureterolithiasis in Preschool Children. 61
31555620 2019
19
Early ureteroscopic treatment in patients with urosepsis associated with ureteral calculi is a safe approach. A pilot study. 61
31482023 2019
20
Re: Minimizing the Cost of Treating Asymptomatic Ureterolithiasis. 61
30577359 2019
21
Ureterolithiasis and the quest for rational use of diagnostic imaging methods. 61
30559568 2018
22
Use of a subcutaneous ureteral bypass device for treatment of benign ureteral obstruction in cats: 174 ureters in 134 cats (2009-2015). 61
30398425 2018
23
Bilateral ureterolithiasis: A true positive and false negative PoCUS exam in a patient with renal colic. 61
29606152 2018
24
Acute synchronous appendicitis and obstructing ureterolithiasis. 61
30108673 2018
25
Epidemiological and imaging features that can affect the detection of ureterolithiasis on ultrasound. 61
30369654 2018
26
CONTACT ULTRASOUND LITHOTRIPSY DURING URETEROLITHIASIS THERAPY. AN ANALYSIS OF LATE POSTOPERATIVE COMPLICATIONS. 61
30358535 2018
27
Perinephric Fat Stranding Is Associated with Elevated Creatinine Among Patients with Acutely Obstructing Ureterolithiasis. 61
29943669 2018
28
Does fasting in Ramadan increase the risk of developing urinary stones? 61
29738008 2018
29
Outcome of ureteral stent placement for treatment of benign ureteral obstruction in dogs: 44 cases (2010-2013). 61
29504861 2018
30
[Results of laparoscopic ureterolithotomy depending on the type of laparoscopic approach and location of the stone]. 61
29634145 2018
31
Predictive value of secondary signs of obstruction in follow-up computed tomography of ureteral stones: a study with dynamic computed tomography. 61
29037128 2018
32
Differential diagnoses of magnetic resonance imaging for suspected acute appendicitis in pregnant patients. 61
29290892 2018
33
Treatment of fungal pyelonephritis and ureterolithiasis with a subcutaneous ureteral bypass system and systemic antifungal medication in a cat. 61
30568915 2018
34
An Accurate Diagnostic Pathway Helps to Correctly Distinguish Between the Possible Causes of Acute Scrotum. 61
29468000 2018
35
Influence of acetylsalicylic acid and low-molecular weight heparins on the formation of renal hematoma after shock wave lithotripsy. 61
28702844 2017
36
[Biomarkers of renal injury in contact ureteral lithotripsy]. 61
29135147 2017
37
Emergency Ureteral Stone Treatment Score Predicts Outcomes of Ureteroscopic Intervention in Acute Obstructive Uropathy Secondary to Urolithiasis. 61
28637368 2017
38
Medical expulsive therapy use in emergency department patients diagnosed with ureteral stones. 61
28291706 2017
39
Different Approaches to Detect "Nanobacteria" in Patients with Kidney Stones: an Infectious Cause or a Subset of Life? 61
28853105 2017
40
Comparison between double-pigtail ureteral stents and ureteral bypass devices for treatment of ureterolithiasis in cats. 61
28763282 2017
41
[Questions of terminology, systematization and grading of complications of contact ureteral lithotripsy]. 61
28845938 2017
42
Imaging of Acute Pelvic Pain in Girls: Ovarian Torsion and Beyond☆. 61
28185689 2017
43
Case control study: hyperbaric oxygen treatment of mild traumatic brain injury persistent post-concussion syndrome and post-traumatic stress disorder. 61
29152209 2017
44
A Comparison of Urolithiasis in the Presence and Absence of Microscopic Hematuria in the Emergency Department. 61
28611901 2017
45
Perioperative Occlusion of a Subcutaneous Ureteral Bypass Secondary to a Severe Pyonephrosis in a Birman Cat. 61
28992905 2017
46
Ureterolithiasis: Management in an environment with limited facilities. 61
28513524 2017
47
Medical Expulsive Therapy for Ureterolithiasis: The EAU Recommendations in 2016. 61
27506951 2017
48
Can Doppler ultrasonography twinkling artifact be used as an alternative imaging modality to non-contrast-enhanced computed tomography in patients with ureteral stones? A prospective clinical study. 61
27170278 2017
49
Glomerular filtration rate determination by computed tomography in two pet rabbits with renal disease. 61
28263109 2017
50
Comparison of prone vs. supine unenhanced CT imaging in patients with clinically suspected ureterolithiasis. 61
27670877 2017
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Variations for Ureterolithiasis

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Expression for Ureterolithiasis

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Search GEO for disease gene expression data for Ureterolithiasis.
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Pathways for Ureterolithiasis

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Pathways related to Ureterolithiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Calcium signaling pathway 36
Show member pathways
 11.8 CHRM3 ADRA1D ADRA1A
2
Myometrial Relaxation and Contraction Pathways 1
Show member pathways
 11.75 CHRM4 CHRM3 ADRA1D ADRA1A
3
Salivary secretion 36
Show member pathways
 11.66 CHRM3 ADRA1D ADRA1A
4
Monoamine GPCRs 1
Show member pathways
 10.97 CHRM4 CHRM3 ADRA1D ADRA1A
5
Sympathetic Nerve Pathway (Neuroeffector Junction) 60
10.52 ADRA1D ADRA1A
Sources

GO Terms for Ureterolithiasis

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Biological processes related to Ureterolithiasis according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of vasoconstriction GO:0045907 9.52 ADRA1D ADRA1A
2 G protein-coupled serotonin receptor signaling pathway GO:0098664 9.51 CHRM4 CHRM3
3 activation of phospholipase C activity GO:0007202 9.49 PTH ADRA1A
4 positive regulation of cardiac muscle hypertrophy GO:0010613 9.48 PDE5A ADRA1A
5 regulation of vasoconstriction GO:0019229 9.46 CHRM3 ADRA1A
6 adenylate cyclase-activating adrenergic receptor signaling pathway GO:0071880 9.43 ADRA1D ADRA1A
7 smooth muscle contraction GO:0006939 9.4 CHRM3 ADRA1A
8 G protein-coupled acetylcholine receptor signaling pathway GO:0007213 9.37 CHRM4 CHRM3
9 adrenergic receptor signaling pathway GO:0071875 9.32 ADRA1D ADRA1A
10 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway GO:0007197 9.26 CHRM4 CHRM3
11 positive regulation of heart rate by epinephrine-norepinephrine GO:0001996 9.16 ADRA1D ADRA1A
12 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001994 8.96 ADRA1D ADRA1A
13 positive regulation of smooth muscle contraction GO:0045987 8.8 CHRM3 ADRA1D ADRA1A

Molecular functions related to Ureterolithiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 G protein-coupled serotonin receptor activity GO:0004993 9.26 CHRM4 CHRM3
2 adrenergic receptor activity GO:0004935 9.16 ADRA1D ADRA1A
3 G protein-coupled acetylcholine receptor activity GO:0016907 8.96 CHRM4 CHRM3
4 alpha1-adrenergic receptor activity GO:0004937 8.62 ADRA1D ADRA1A
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Sources for Ureterolithiasis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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