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MCID: URT014
MIFTS: 43

Ureterolithiasis

Categories: Nephrological diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Ureterolithiasis

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MalaCards integrated aliases for Ureterolithiasis:

Name: Ureterolithiasis 12 44 15 17 71
Calculus of Ureter 12 32
Ureteric Calculus 12
Ureteral Calculi 71
Ureteric Stone 12

Classifications:

MalaCards categories:
Anatomical: Nephrological diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:14146
ICD9CM 34 592.1
MeSH 44 D053039
NCIt 50 C114696
SNOMED-CT 67 31054009
ICD10 32 N20.1
UMLS 71 C0041952 C1456865
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Summaries for Ureterolithiasis

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Disease Ontology : 12 An ureteral disease this is characterized by the formation of stoney concentrations in the ureter.

MalaCards based summary : Ureterolithiasis, also known as calculus of ureter, is related to nephrolithiasis and adenine phosphoribosyltransferase deficiency. An important gene associated with Ureterolithiasis is APRT (Adenine Phosphoribosyltransferase), and among its related pathways/superpathways are cGMP-PKG signaling pathway and Calcium signaling pathway. The drugs Sodium citrate and Morphine have been mentioned in the context of this disorder. Affiliated tissues include kidney, colon and adrenal gland, and related phenotype is Decreased substrate adherent cell growth.

Wikipedia : 74 Kidney stone disease, also known as nephrolithiasis or urolithiasis, is when a solid piece of material... more...

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Related Diseases for Ureterolithiasis

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Diseases related to Ureterolithiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 81)
# Related Disease Score Top Affiliating Genes
1 nephrolithiasis 30.6 PTH APRT AGXT
2 adenine phosphoribosyltransferase deficiency 29.9 APRT AGXT
3 hydronephrosis 10.4
4 ureteral obstruction 10.4
5 urolithiasis 10.3
6 pyelonephritis 10.2
7 prostatic hyperplasia, benign 10.2 PDE5A ADRA1A
8 appendicitis 10.2
9 dental abscess 10.2 PTH CRP
10 suppurative thyroiditis 10.2 PTH CRP
11 parametritis 10.2 PTH CRP
12 pulmonary valve insufficiency 10.2 PDE5A CRP
13 enthesopathy 10.2 PTH CRP
14 spondylolisthesis 10.2 PTH CRP
15 raynaud disease 10.2 PDE5A CRP
16 renal tuberculosis 10.1 CRP AGXT
17 spondylosis 10.1 PTH CRP
18 nasopharyngitis 10.1 PDE5A CRP
19 d-glyceric aciduria 10.1 GLYCTK AGXT
20 tricuspid valve disease 10.1 PDE5A CRP
21 peritonitis 10.1
22 tricuspid valve insufficiency 10.1 PDE5A CRP
23 lactose intolerance 10.1 PTH CRP
24 priapism 10.1 PDE5A ADRA1A
25 xanthinuria 10.1 APRT AGXT
26 urinary tract infection 10.1
27 urinary tract obstruction 10.1
28 chronic kidney disease 10.1
29 neurogenic bladder 10.0 PDE5A CRP
30 mineral metabolism disease 10.0 PTH CRP
31 chromosome 2q37 deletion syndrome 10.0 PTH AGXT
32 bladder exstrophy 10.0
33 prostatic hypertrophy 10.0
34 transitional cell carcinoma 10.0
35 nephrolithiasis, calcium oxalate 10.0
36 ureterocele 10.0
37 vesicoureteral reflux 1 10.0
38 hyperparathyroidism 10.0
39 endometriosis 10.0
40 anuria 10.0
41 kidney disease 10.0
42 acute pyelonephritis 10.0
43 diverticulitis 10.0
44 disease by infectious agent 9.9
45 thrombosis 9.9
46 covid-19 9.9
47 adult respiratory distress syndrome 9.9
48 male infertility 9.9
49 azoospermia 9.9
50 severe acute respiratory syndrome 9.9

Comorbidity relations with Ureterolithiasis via Phenotypic Disease Network (PDN): (show all 12)


Acute Cystitis Bladder Neck Obstruction
Hydronephrosis Nephrolithiasis, Uric Acid
Nephrolithiasis, X-Linked Recessive, with Renal Failure Paralytic Ileus
Prostate Cancer Prostatic Hypertrophy
Pyelonephritis Urethral Calculus
Urethral Stricture Urinary Tract Obstruction

Graphical network of the top 20 diseases related to Ureterolithiasis:



Diseases related to Ureterolithiasis
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Symptoms & Phenotypes for Ureterolithiasis

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GenomeRNAi Phenotypes related to Ureterolithiasis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased substrate adherent cell growth GR00193-A-1 8.8 ADRA1A ADRA1B ADRA1D
Sources

Drugs & Therapeutics for Ureterolithiasis

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Drugs for Ureterolithiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 55)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sodium citrate Approved, Investigational Phase 4 68-04-2
2
Morphine Approved, Investigational Phase 4 57-27-2 5288826
3
Ketoprofen Approved, Vet_approved Phase 4 22071-15-4 3825
4
Nefopam Approved, Investigational Phase 4 13669-70-0
5
Acetaminophen Approved Phase 4 103-90-2 1983
6
parecoxib Approved Phase 4 198470-84-7
7
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
8
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
9
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
10
Tadalafil Approved, Investigational Phase 4 171596-29-5 110635
11
Tamsulosin Approved, Investigational Phase 4 106133-20-4 129211
12
Silodosin Approved Phase 4 160970-54-7
13
Citric acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
14 Citrate Phase 4
15 Sildenafil Citrate Phase 4 171599-83-0
16 Antipyretics Phase 4
17 Antibiotics, Antitubercular Phase 4
18 Anti-Bacterial Agents Phase 4
19 Anti-Infective Agents Phase 4
20 Cytochrome P-450 Enzyme Inhibitors Phase 4
21 Narcotics Phase 4
22 Analgesics, Opioid Phase 4
23 Vasodilator Agents Phase 4
24 Phosphodiesterase Inhibitors Phase 4
25 Phosphodiesterase 5 Inhibitors Phase 4
26
Prazosin Approved Phase 3 19216-56-9 4893
27
Doxazosin Approved Phase 3 74191-85-8 3157
28
Nifedipine Approved Phase 3 21829-25-4 4485
29
Tramadol Approved, Investigational Phase 3 27203-92-5 33741
30
Aceclofenac Approved, Investigational Phase 3 89796-99-6 71771
31 Naftopidil Investigational Phase 3 57149-07-2
32 Tocolytic Agents Phase 3
33 Antihypertensive Agents Phase 3
34 Hormones Phase 3
35 Calcium, Dietary Phase 3
36 calcium channel blockers Phase 3
37 Platelet Aggregation Inhibitors Phase 3
38
Calcium Nutraceutical Phase 3 7440-70-2 271
39
Mirabegron Approved Phase 2 223673-61-8 9865528
40 Adrenergic beta-Agonists Phase 2
41 Adrenergic beta-3 Receptor Agonists Phase 2
42 Adrenergic Agonists Phase 2
43
Lidocaine Approved, Vet_approved 137-58-6 3676
44
Ibuprofen Approved 15687-27-1 3672
45
Racepinephrine Approved 329-65-7 838
46
Epinephrine Approved, Vet_approved 51-43-4 5816
47
tannic acid Approved 1401-55-4
48
Benzocaine Approved, Investigational 1994-09-7, 94-09-7 2337
49
Manganese Approved, Nutraceutical 7439-96-5 27854
50 Sodium Channel Blockers

Interventional clinical trials:

(show top 50) (show all 83)
# Name Status NCT ID Phase Drugs
1 Role of Phosphodiesterase 5 Inhibitors (PDE5i) (Sildenafil) in Management of Distal Ureteral Stone Unknown status NCT02519153 Phase 4 Sildenafil
2 A Comparison Between Flexible Ureteroscopy, Semirigid Ureteroscopy and Extracorporeal Shockwaves Lithotripsy (SWL) in The Management of Proximal Ureteric Stones. A Randomized Controlled Trial Unknown status NCT02469766 Phase 4
3 Efficacy of Tamsulosin OCAS in the Conjunctive Medical Treatment of Distal Ureteral Stones.A Randomized, Double-blind, Placebo-controlled Study Unknown status NCT01167062 Phase 4 Tamsulosin Hydrochloride OCAS 0.4 mg
4 The Use of Medical-Expulsive Therapy With Alfuzocine xl 10mg x1/d for Distal Ureterolithiasis.a Randomized Prospective Study Unknown status NCT00489112 Phase 4 Alfuzocine XL 10 mg once a day
5 The Efficacy of Alpha-blockers for Expulsion of Distal Ureteral Stones Unknown status NCT00451061 Phase 4 Alfuzosin;Tamsulosin
6 A 4-week, Double-blind, Randomized, Comparative and Multi-center Clinical Trial to Evaluate the Efficacy and Safety of Silodosin in the Treatment of Natural Expulsion in Patients With Ureteral Stones. Completed NCT01533389 Phase 4 Silodosin;Placebo
7 Interest of Néfopam in the Treatment of Pain During the Intense Ureteral Calculi Uncomplicated in Adults in Emergencies Unit. Completed NCT00639574 Phase 4 Néfopam
8 Parecoxib vs Paracetamol in the Treatment of Acute Renal Colic Due to Ureteric Calculi: Randomized Controlled Trial Completed NCT03704623 Phase 4 Paracetamol;Parecoxib
9 Study of Tamsulosin for Urolithiasis in the Emergency Department Completed NCT00382265 Phase 4 tamsulosin
10 A Multicenter Randomized Controlled Trial Assessing the Efficacy of Antimicrobial Prophylaxis for Extracorporeal Shock Wave Lithotripsy on Reducing Urinary Tract Infection Recruiting NCT03692715 Phase 4 Ciprofloxacin;Placebo
11 Study of Ketorolac Versus Opioid for Pain After Endoscopy (SKOPE): A Double-blinded Randomized Control Trial Comparing Outpatient Analgesic Efficacy of NSAIDs and Opioids in Patients Undergoing Ureteroscopy for Kidney Stones Recruiting NCT03888144 Phase 4 Oxycodone;Ketorolac
12 Comparative Study Between Tadalafil Versus Tamsulosin as a Medical Expulsive Therapy for Lower Ureteric Stones Active, not recruiting NCT04641507 Phase 4 Tadalafil versus tamsulosin as MET
13 Comparison of Silodosin vs. Tamsulosin on Spontaneous Passage of Acutely Obstructing Ureteral Calculi in Medical Expulsive Therapy Terminated NCT02369744 Phase 4 Silodosin;Tamsulosin
14 Efectividad de la Tamsulosina Como Tratamiento Adyuvante Previo a Ureterolitotomia Endoscopica Terminated NCT03614052 Phase 4 Tamsulosin Hydrochloride 0.4 milligrams;Placebo Oral Tablet
15 Celecoxib in the Management of Acute Renal Colic Withdrawn NCT00304317 Phase 4 celecoxib
16 Evaluation of Alfuzosin as Medical Expulsion Therapy for Ureteral Stones Unknown status NCT00713739 Phase 3 Alfuzosin;nifedipine;doxazosin;prazosin
17 Interest of a Treatment With the alpha1-blocker Tamsulosin in the Elimination of Pelvis Ureteral Stones Completed NCT00151567 Phase 3 Tamsulosin;Placebo
18 Effect of Perioperative Selective alpha1-blockers in Non-stented Ureteroscopic Laser Lithotripsy for Ureteric Stones Completed NCT04557202 Phase 3 Tamsulosin Oral Capsule;Placebo
19 Alfuzosin Hydrochloride to Promote Passage of Distal Ureteral Calculi Completed NCT00177086 Phase 3
20 Medical Expulsive Therapy for Ureter Stone Using Naftopidil: Multicenter, Randomized, Double-blind, Placebo Controlled Study Completed NCT01952314 Phase 3 Naftopidil 75mg;Placebo for Naftopidil;Standard treatment
21 To Investigate if Alpha-blocker Therapy (Alfuzosin) Increases Stone Free Rates and Improves Pain Control After ESWL (Extra-corporeal Shock Wave Lithotripsy) for Renal and Ureteric Stones. Withdrawn NCT00388271 Phase 3 Alfuzosin (Xatral);standard treatment
22 Phase II Study Comparing Two Groups of Patients Undergoing ESWL Treated With Ureteral Stents Versus Expulsion Therapy With Tamsulosin Unknown status NCT00478998 Phase 2 Tamsulosin
23 Prospective Randomized Placebo Controlled Blinded Study to Evaluate the Efficacy of Alfuzosin (Alpha Blocker) on the Success Rates Following SWL. Unknown status NCT00409227 Phase 2 Alpha blocker-alfuzosin;placebo
24 A Double-Blind, Placebo-Controlled Study of Silodosin to Facilitate Urinary Stone Passage Completed NCT01144949 Phase 2 silodosin;placebo
25 A Double Blind Placebo Control Trial of Mirabegron for Medical Expulsive Therapy and to Manage Stent Pain for Ureteral Stones(Protocol # 01-16-20-02) Completed NCT02744430 Phase 2 Mirabegron
26 Efficacy and Safety of Renalof® in the Removal of Calculi Smaller Than 10 mm Located in the Reno-Ureteral Tract Completed NCT04695951 Phase 2
27 URIPRENE: Feasibility Study to Evaluate the Preliminary Safety and Effectiveness of the Uriprene Stent Following Uncomplicated Ureteroscopy Completed NCT02032316 Phase 1
28 The Alternating Bidirectional Versus The Standard Approach During Shock Wave Lithotripsy For Renal And Upper Lumbar Ureteric Stones. A Randomized Clinical Trial Unknown status NCT03243682
29 The Use of Tamsulosin in Treatment of (10-15 mm) Lower Ureteric Stones in Adults With Non-emergent Symptoms: A Prospective Randomized Study Unknown status NCT03274700 Early Phase 1 Tamsulosin.;Placebo.
30 External Physical Vibration Lithecbole(EPVL) Versus Traditional Treatment for 4-10 mm Ureteral Stone: A Multi-center Prospective Randomized Controlled Trial Unknown status NCT03730389
31 Ultrasound Guided Ureteroscopy for the Treatment of Lower Third Ureteric Stones in Adults Unknown status NCT03404986
32 Impact of Low Dose Fluoroscopy in Ureteroscopy Unknown status NCT02704949
33 The Impact of Silent Ureteral Stone on Renal Function and Kidney Anatomy: a Prospective Analysis Unknown status NCT01884870
34 Comparative Study in Patients With Lower Ureteral Stones Treated With 10 MG Alfuzosin,10 MG Alfuzosin With Rowatinex, and Rowatinex Alone Unknown status NCT00397397
35 Intraureteral of Alkalinized Lidocaine as Novel Approach to Post-Ureteroscopy Pain: Double-blind Prospective Randomized Controlled Trial Unknown status NCT01450566 Lidocaine;Saline
36 Prospective Comparison Between Different Laser Settings for Ureteral \ Kidney Stones Treatment During Unknown status NCT02279927
37 Ultrasound Non-contrast Computed Tomography Real-time Fusion for Urinary Stones Follow up Unknown status NCT02539004
38 Staged Ureteroscopy After Initial Urinary Drainage Versus Direct Ureteroscopy in the Treatment of Pediatric Obstructive Calcular Anuria Unknown status NCT02139059
39 Shockwave Lithotripsy (SWL) Under Regular General Anesthesia and Under General Anesthesia Using Bronchial Blocker. Unknown status NCT01008267
40 Optimal Method of Decompression of the Renal Collecting System in Acute Obstruction: a Prospective Randomised Trial Unknown status NCT02929160
41 Ultraslow Full-power SWL Versus Slow SWL in Stones With High Attenuation Value Completed NCT03795545
42 The Role of Flexible Cystoscopy in Laparoscopic Stone Surgery: a Single Surgeon Experience Completed NCT01277198
43 Comparing Uretersocopy With Versus Without Use of Guide-wire in Treatment of Ureteral Stone Completed NCT03726502
44 The Use of Non-contrast Helical Computerized Tomogram in Predicting Treatment Outcome of Upper Ureteric Stone by Extracorporeal Shock Wave Lithotripsy Using the Sonolith 4000+ Lithotripter Completed NCT00517205
45 Comparative Study of Extracorporeal Shock Wave Lithotripsy and Ureteroscopy in Management of Upper Third Ureteral Calculi Completed NCT03559738
46 Evaluation of the Effect of Masturbation on Distal Ureteral Stones: A Prospective Randomized Controlled Study Completed NCT04550559
47 Medical Expulsive Therapy of Single Distal Ureteral Stones. A Randomised, Double-blind and Placebo-controlled Study Completed NCT00831701 Tamsulosin;Placebo
48 Is Prophylactic Antibiotics Necessary In Otherwise Healthy Adult Patients Undergoing Ureteroscopic Procedures for Ureteral Stones? Completed NCT02635490
49 The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients Completed NCT00448123 Tamsulosin;Placebo
50 The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients Completed NCT00600405 tamsulosin;Standard therapy with ibuprofen and oxycodone.

Search NIH Clinical Center for Ureterolithiasis

Cochrane evidence based reviews: ureterolithiasis

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Genetic Tests for Ureterolithiasis

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Anatomical Context for Ureterolithiasis

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MalaCards organs/tissues related to Ureterolithiasis:

40
Kidney, Colon, Adrenal Gland, Ovary, Neutrophil
Sources

Publications for Ureterolithiasis

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Articles related to Ureterolithiasis:

(show top 50) (show all 343)
# Title Authors PMID Year
1
Rare late presentation of bilateral single system intravesical ureteroceles complicated with ureterolithiasis: Case report and literature review. 61
33489768 2021
2
The burden of the pandemic on the non-SARS-CoV-2 emergencies: A multicenter study. 61
33429189 2021
3
[A severe course of struvite stones in the upper and lower urinary tract of a 52-year-old man]. 61
32876698 2020
4
Immediate Shockwave Lithotripsy vs Delayed Shockwave Lithotripsy After Urgent Ureteral Stenting in Patients with Ureteral or Pyeloureteral Urolithiasis: A Matched-Pair Analysis. 61
33218266 2020
5
The Use of Serum Procalcitonin in the Setting of Infected Ureteral Stones: A Prospective Observational Study. 61
32998591 2020
6
Validity of STONE Score in Clinical Prediction of Ureteral Stone Disease. 61
33235599 2020
7
Re: Shared Decision Making in Patients With Suspected Uncomplicated Ureterolithiasis: A Decision Aid Development Study. 61
33277743 2020
8
A Tale From the Early Stone Age: Pediatric Ureterolithiasis as Appendicitis Mimic - A Case Report and Management Overview. 61
33123450 2020
9
Renal pelvic rupture, intrapelvic haematoma and retroperitoneal haemorrhage associated with obstructive ureterolithiasis in a cat. 61
32909260 2020
10
Placement of ureteral stents in three rabbits for the treatment of obstructive ureterolithiasis. 61
32767358 2020
11
Shared Decision Making in Patients With Suspected Uncomplicated Ureterolithiasis: A Decision Aid Development Study. 61
32064724 2020
12
Outcome of SUB placement for the treatment of benign ureteral obstruction in dogs: nine dogs and 12 renal units (2013 to 2017). 61
32352170 2020
13
Boari-Flap reconstrution due to a total ureteral avulsion in a patient with ipslateral ureterolithiasis and contralateral renal nodule. 61
32025494 2020
14
Uretero-Cutaneous Fistula and Renal Abscessation as a Complication of Ureteral Stenting in a Dog. 61
32182106 2020
15
Identification of ureteral stones at reduced radiation exposure: a pilot study comparing conventional versus digital low-dosage linear slot scanning (Lodox®) radiography. 61
31165230 2020
16
Renal Forniceal Rupture in the Setting of Obstructing Ureteral Stones: An Analysis of Stone Characterization and Urologic Intervention Pattern. 61
31950872 2020
17
Ultra-Low-Dose CT: An Effective Follow-Up Imaging Modality for Ureterolithiasis. 61
31663371 2020
18
Evaluation of Preoperative Tamsulosin Role in Facilitating Ureteral Orifice Navigation for School-Age Pediatric Ureteroscopy. 61
33235880 2020
19
Asymptomatic Obstructive Ureterolithiasis Due to a Periureteral Venous Ring. 61
33457714 2020
20
Comparison of the Diagnostic Values of Leukocytes, Neutrophils, Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Distinguishing between Acute Appendicitis and Right Ureterolithiasis. 61
32013359 2020
21
Effectiveness of medical expulsive therapy with the ɲ-adrenergic blocker tamsulosin for distal ureterolithiasis in adults attended in an emergency department in Chile. 61
31777212 2019
22
Renal Tuberculosis: The Masquerader. 61
32041921 2019
23
[Abdominal ultrasound in emergency and critical care medicine]. 61
30840096 2019
24
Narcotic Pain Control for Ureterolithiasis Is Associated With Unnecessary Repeat Imaging in the Emergency Department. 61
30358635 2019
25
Dynamic thiol/disulfide homeostasis as a novel indicator of oxidative stress in patients with urolithiasis. 61
31294135 2019
26
Limited sensitivity and size over measurements of ultrasound affect medical decisions for ureteral stone compared to non-contrasted computed tomography. 61
30109485 2019
27
Medical and Interventional Management of Upper Urinary Tract Uroliths. 61
30736892 2019
28
Unconventional natural gas development and hospitalizations: evidence from Pennsylvania, United States, 2003-2014. 61
30677623 2019
29
Clinical Effects of Polymyxin B Hemoperfusion in Patients With Septic Shock Caused by Urinary Tract Infection. 61
30209889 2019
30
Interest of URS-L in the Treatment of Ureterolithiasis in Preschool Children. 61
31555620 2019
31
Re: Minimizing the Cost of Treating Asymptomatic Ureterolithiasis. 61
30577359 2019
32
Early ureteroscopic treatment in patients with urosepsis associated with ureteral calculi is a safe approach. A pilot study. 61
31482023 2019
33
Alteplase Instillation for Upper Urinary Tract Clot Dissolution. 61
32760798 2019
34
Ureterolithiasis and the quest for rational use of diagnostic imaging methods. 61
30559568 2018
35
Use of a subcutaneous ureteral bypass device for treatment of benign ureteral obstruction in cats: 174 ureters in 134 cats (2009-2015). 61
30398425 2018
36
Bilateral ureterolithiasis: A true positive and false negative PoCUS exam in a patient with renal colic. 61
29606152 2018
37
Acute synchronous appendicitis and obstructing ureterolithiasis. 61
30108673 2018
38
Epidemiological and imaging features that can affect the detection of ureterolithiasis on ultrasound. 61
30369654 2018
39
CONTACT ULTRASOUND LITHOTRIPSY DURING URETEROLITHIASIS THERAPY. AN ANALYSIS OF LATE POSTOPERATIVE COMPLICATIONS. 61
30358535 2018
40
Perinephric Fat Stranding Is Associated with Elevated Creatinine Among Patients with Acutely Obstructing Ureterolithiasis. 61
29943669 2018
41
Does fasting in Ramadan increase the risk of developing urinary stones? 61
29738008 2018
42
Outcome of ureteral stent placement for treatment of benign ureteral obstruction in dogs: 44 cases (2010-2013). 61
29504861 2018
43
[Results of laparoscopic ureterolithotomy depending on the type of laparoscopic approach and location of the stone]. 61
29634145 2018
44
Predictive value of secondary signs of obstruction in follow-up computed tomography of ureteral stones: a study with dynamic computed tomography. 61
29037128 2018
45
Differential diagnoses of magnetic resonance imaging for suspected acute appendicitis in pregnant patients. 61
29290892 2018
46
Treatment of fungal pyelonephritis and ureterolithiasis with a subcutaneous ureteral bypass system and systemic antifungal medication in a cat. 61
30568915 2018
47
An Accurate Diagnostic Pathway Helps to Correctly Distinguish Between the Possible Causes of Acute Scrotum. 61
29468000 2018
48
Influence of acetylsalicylic acid and low-molecular weight heparins on the formation of renal hematoma after shock wave lithotripsy. 61
28702844 2017
49
[Biomarkers of renal injury in contact ureteral lithotripsy]. 61
29135147 2017
50
Emergency Ureteral Stone Treatment Score Predicts Outcomes of Ureteroscopic Intervention in Acute Obstructive Uropathy Secondary to Urolithiasis. 61
28637368 2017
Sources

Variations for Ureterolithiasis

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Expression for Ureterolithiasis

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Search GEO for disease gene expression data for Ureterolithiasis.
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Pathways for Ureterolithiasis

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Pathways related to Ureterolithiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
cGMP-PKG signaling pathway 36
Show member pathways
 12.06 PDE5A ADRA1D ADRA1B ADRA1A
2
Calcium signaling pathway 36
11.99 ADRA1D ADRA1B ADRA1A
3
Myometrial Relaxation and Contraction Pathways 1
Show member pathways
 11.95 CHRM4 ADRA1D ADRA1B ADRA1A
4
AMPK Enzyme Complex Pathway 63
Show member pathways
 11.78 ADRA1D ADRA1B ADRA1A
5
Translation Translation regulation by Alpha-1 adrenergic receptors 23
Show member pathways
 11.58 ADRA1D ADRA1B ADRA1A
6
Monoamine GPCRs 1
Show member pathways
 11.3 CHRM4 ADRA1D ADRA1B ADRA1A
7
Glyoxylate and dicarboxylate metabolism 36
10.88 GLYCTK AGXT
8
Sympathetic Nerve Pathway (Neuroeffector Junction) 60
10.16 ADRA1D ADRA1B ADRA1A
Sources

GO Terms for Ureterolithiasis

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Biological processes related to Ureterolithiasis according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 G protein-coupled receptor signaling pathway GO:0007186 9.92 PTH CHRM4 ADRA1D ADRA1B ADRA1A
2 positive regulation of cytosolic calcium ion concentration GO:0007204 9.67 ADRA1D ADRA1B ADRA1A
3 cell-cell signaling GO:0007267 9.67 PTH ADRA1D ADRA1B ADRA1A
4 positive regulation of MAPK cascade GO:0043410 9.58 ADRA1D ADRA1B ADRA1A
5 activation of phospholipase C activity GO:0007202 9.51 PTH ADRA1A
6 phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200 9.5 ADRA1D ADRA1B ADRA1A
7 regulation of cardiac muscle contraction GO:0055117 9.48 ADRA1B ADRA1A
8 regulation of vasoconstriction GO:0019229 9.46 ADRA1B ADRA1A
9 regulation of muscle contraction GO:0006937 9.43 ADRA1B ADRA1A
10 positive regulation of vasoconstriction GO:0045907 9.43 ADRA1D ADRA1B ADRA1A
11 adenylate cyclase-activating adrenergic receptor signaling pathway GO:0071880 9.33 ADRA1D ADRA1B ADRA1A
12 adrenergic receptor signaling pathway GO:0071875 9.13 ADRA1D ADRA1B ADRA1A
13 positive regulation of heart rate by epinephrine-norepinephrine GO:0001996 8.8 ADRA1D ADRA1B ADRA1A

Molecular functions related to Ureterolithiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 adrenergic receptor activity GO:0004935 9.13 ADRA1D ADRA1B ADRA1A
2 alpha1-adrenergic receptor activity GO:0004937 8.8 ADRA1D ADRA1B ADRA1A
Sources

Sources for Ureterolithiasis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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